Amedee des Georges

City University of New York, New York, NY, United States 
Structural biology, translation control
"Amedee des Georges"


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Linda A. Amos grad student 2004-2008 MRC-LMB (Chemistry Tree)
Jan Löwe grad student 2004-2008 MRC-LMB
Joachim Frank post-doc 2009-2015 Columbia University HHMI


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Dominique Gutierrez grad student 2017- CUNY
Da Cui grad student 2018- CUNY
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Dashti A, Mashayekhi G, Shekhar M, et al. (2020) Retrieving functional pathways of biomolecules from single-particle snapshots. Nature Communications. 11: 4734
Santulli G, Lewis D, des Georges A, et al. (2018) Ryanodine Receptor Structure and Function in Health and Disease. Sub-Cellular Biochemistry. 87: 329-352
des Georges A, Clarke OB, Zalk R, et al. (2016) Structural Basis for Gating and Activation of RyR1. Cell. 167: 145-157.e17
des Georges A, Dhote V, Kuhn L, et al. (2015) Structure of mammalian eIF3 in the context of the 43S preinitiation complex. Nature. 525: 491-5
Zalk R, Clarke OB, des Georges A, et al. (2015) Structure of a mammalian ryanodine receptor. Nature. 517: 44-9
des Georges A, Hashem Y, Unbehaun A, et al. (2014) Structure of the mammalian ribosomal pre-termination complex associated with eRF1.eRF3.GDPNP. Nucleic Acids Research. 42: 3409-18
Hashem Y, des Georges A, Dhote V, et al. (2013) Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit. Nature. 503: 539-43
Hashem Y, des Georges A, Dhote V, et al. (2013) Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29. Cell. 153: 1108-19
Hashem Y, des Georges A, Fu J, et al. (2013) High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome. Nature. 494: 385-9
Sharma G, Pallesen J, Das S, et al. (2013) Affinity grid-based cryo-EM of PKC binding to RACK1 on the ribosome. Journal of Structural Biology. 181: 190-4
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