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Federico Forneris - Publications

Affiliations: 
2002-2002 Chemical Sciences University of Trieste, Italy, Trieste, Friuli-Venezia Giulia, Italy 
 2003-2008 Genetics and Microbiology University of Pavia, Pavia, PV, Italy 
 2009-2013 Crystal and Structure Chemistry Utrecht University, Utrecht, Netherlands 
 2014- Biology and Biotechnology University of Pavia, Pavia, PV, Italy 
Area:
Large Macromolecular Complexes, Extracellular Proteins, Enzymes
Website:
http://fornerislab.unipv.it
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Selvanathan A, Nixon CY, Zhu Y, Scietti L, Forneris F, Uribe LMM, Lidral AC, Jezewski PA, Mulliken JB, Murray JC, Buckley MF, Cox TC, Roscioli T. Mutation Distribution and Type Suggests Genetic Differences between the Etiology of Orofacial Clefting and Gastric Cancer. Genes. 11. PMID 32260281 DOI: 10.3390/Genes11040391  0.735
2020 Guarino SR, Canciani A, Forneris F. Dissecting the Extracellular Complexity of Neuromuscular Junction Organizers. Frontiers in Molecular Biosciences. 6: 156. PMID 31998752 DOI: 10.3389/Fmolb.2019.00156  0.743
2019 Marconcini M, Hernandez L, Iovino G, Houé V, Valerio F, Palatini U, Pischedda E, Crawford JE, White BJ, Lin T, Carballar-Lejarazu R, Ometto L, Forneris F, Failloux AB, Bonizzoni M. Polymorphism analyses and protein modelling inform on functional specialization of Piwi clade genes in the arboviral vector Aedes albopictus. Plos Neglected Tropical Diseases. 13: e0007919. PMID 31790401 DOI: 10.1371/Journal.Pntd.0007919  0.413
2019 Ewans LJ, Colley A, Gaston-Massuet C, Gualtieri A, Cowley MJ, McCabe MJ, Anand D, Lachke S, Scietti L, Forneris F, Zhu Y, Ying K, Walsh C, Kirk EP, Miller D, et al. Pathogenic variants in result in a Stickler syndrome-like connective tissue disorder with vascular complications. Journal of Medical Genetics. PMID 31129566 DOI: 10.1136/Jmedgenet-2019-106019  0.729
2019 Marabelli C, Marrocco B, Pilotto S, Chittori S, Picaud S, Marchese S, Ciossani G, Forneris F, Filippakopoulos P, Schoehn G, Rhodes D, Subramaniam S, Mattevi A. A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Reports. 27: 387-399.e7. PMID 30970244 DOI: 10.1016/J.Celrep.2019.03.061  0.628
2019 Canciani A, Catucci G, Forneris F. Structural characterization of the third scavenger receptor cysteine-rich domain of murine neurotrypsin. Protein Science : a Publication of the Protein Society. 28: 746-755. PMID 30748049 DOI: 10.1002/Pro.3587  0.764
2019 Scietti L, Campioni M, Forneris F. SiMPLOD, a Structure-Integrated Database of Collagen Lysyl Hydroxylase (LH/PLOD) Enzyme Variants. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 34: 1376-1382. PMID 30721533 DOI: 10.1002/Jbmr.3692  0.769
2019 Falchetto M, Ciossani G, Scolari F, Di Cosimo A, Nenci S, Field LM, Mattevi A, Zhou JJ, Gasperi G, Forneris F. Structural and biochemical evaluation of Ceratitis capitata odorant-binding protein 22 affinity for odorants involved in intersex communication. Insect Molecular Biology. 28: 431-443. PMID 30548711 DOI: 10.1111/Imb.12559  0.61
2018 Scietti L, Chiapparino A, De Giorgi F, Fumagalli M, Khoriauli L, Nergadze S, Basu S, Olieric V, Cucca L, Banushi B, Profumo A, Giulotto E, Gissen P, Forneris F. Author Correction: Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3. Nature Communications. 9: 3912. PMID 30237434 DOI: 10.1038/S41467-018-06481-X  0.723
2018 Buroni S, Scoffone VC, Fumagalli M, Makarov V, Cagnone M, Trespidi G, Rossi E, Forneris F, Riccardi G, Chiarelli LR. Investigating the Mechanism of Action of Diketopiperazines Inhibitors of the Quorum Sensing Synthase CepI: A Site-Directed Mutagenesis Study. Frontiers in Pharmacology. 9: 836. PMID 30108505 DOI: 10.3389/Fphar.2018.00836  0.436
2018 Scietti L, Chiapparino A, De Giorgi F, Fumagalli M, Khoriauli L, Nergadze S, Basu S, Olieric V, Cucca L, Banushi B, Profumo A, Giulotto E, Gissen P, Forneris F. Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3. Nature Communications. 9: 3163. PMID 30089812 DOI: 10.1038/S41467-018-05631-5  0.78
2018 Falchetto M, Ciossani G, Scolari F, Cosimo AD, Nenci S, Field LM, Mattevi A, Zhou JJ, Gasperi G, Forneris F. Structural and biochemical evaluation of Ceratitis capitata OBP22 affinity for odorants involved in inter-sex communication Insect Molecular Biology. DOI: 10.2210/Pdb6Hhe/Pdb  0.569
2017 Xue X, Wu J, Ricklin D, Forneris F, Di Crescenzio P, Schmidt CQ, Granneman J, Sharp TH, Lambris JD, Gros P. Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses. Nature Structural & Molecular Biology. PMID 28671664 DOI: 10.1038/Nsmb.3427  0.587
2017 Forneris F, Mattevi A. Expanding the structural biology toolbox with single-molecule holography. Proceedings of the National Academy of Sciences of the United States of America. 114: 1448-1450. PMID 28154136 DOI: 10.1073/Pnas.1620897114  0.607
2017 Forneris F, Canciani A, Ciossani G, Palamini M, Chiapparino A, Gabrieli P, Guarino SR, Campioni M, Nenci S, Magnani F. Versatile medium-throughput strategies for recombinant expression screening in structural biology Acta Crystallographica Section a Foundations and Advances. 73: C1276-C1276. DOI: 10.1107/S2053273317082985  0.734
2016 Palamini M, Canciani A, Forneris F. Identifying and Visualizing Macromolecular Flexibility in Structural Biology. Frontiers in Molecular Biosciences. 3: 47. PMID 27668215 DOI: 10.3389/Fmolb.2016.00047  0.761
2016 Speranzini V, Rotili D, Ciossani G, Pilotto S, Marrocco B, Forgione M, Lucidi A, Forneris F, Mehdipour P, Velankar S, Mai A, Mattevi A. Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features. Science Advances. 2: e1601017. PMID 27626075 DOI: 10.1126/Sciadv.1601017  0.615
2016 Banushi B, Forneris F, Straatman-Iwanowska A, Strange A, Lyne AM, Rogerson C, Burden JJ, Heywood WE, Hanley J, Doykov I, Straatman KR, Smith H, Bem D, Kriston-Vizi J, Ariceta G, et al. Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis. Nature Communications. 7: 12111. PMID 27435297 DOI: 10.1038/Ncomms12111  0.422
2016 Spadaro F, Scoffone VC, Chiarelli LR, Fumagalli M, Buroni S, Riccardi G, Forneris F. The crystal structure of Burkholderia cenocepacia DfsA provides insights into substrate recognition and quorum sensing fatty acid biosynthesis. Biochemistry. PMID 27198181 DOI: 10.1021/Acs.Biochem.6B00178  0.471
2016 Forneris F, Wu J, Xue X, Ricklin D, Lin Z, Sfyroera G, Tzekou A, Volokhina E, Granneman JC, Hauhart R, Bertram P, Liszewski MK, Atkinson JP, Lambris JD, Gros P. Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode. The Embo Journal. PMID 27013439 DOI: 10.15252/Embj.201593673  0.584
2016 Savino S, Ferrandi EE, Forneris F, Rovida S, Riva S, Monti D, Mattevi A. Structural and biochemical insights into 7β-hydroxysteroid dehydrogenase stereoselectivity. Proteins. 84: 859-65. PMID 27006087 DOI: 10.1002/Prot.25036  0.568
2016 Xue X, Wu J, Forneris F, Ricklin D, Di Crescenzio P, Schmidt C, Granneman J, Lambris JD, Gros P. Structural insights into cofactor activity Immunobiology. 221: 1193. DOI: 10.1016/J.Imbio.2016.06.152  0.583
2015 Dzurová L, Forneris F, Savino S, Galuszka P, Vrabka J, Frébort I. The three-dimensional structure of "Lonely Guy" from Claviceps purpurea provides insights into the phosphoribohydrolase function of Rossmann fold-containing lysine decarboxylase-like proteins. Proteins. 83: 1539-46. PMID 26010010 DOI: 10.1002/Prot.24835  0.509
2015 Pilotto S, Speranzini V, Tortorici M, Durand D, Fish A, Valente S, Forneris F, Mai A, Sixma TK, Vachette P, Mattevi A. Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation. Proceedings of the National Academy of Sciences of the United States of America. 112: 2752-7. PMID 25730864 DOI: 10.1073/Pnas.1419468112  0.609
2014 Forneris F, Burnley BT, Gros P. Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D. Acta Crystallographica. Section D, Biological Crystallography. 70: 733-43. PMID 24598742 DOI: 10.1107/S1399004713032549  0.606
2013 Peng WC, de Lau W, Madoori PK, Forneris F, Granneman JC, Clevers H, Gros P. Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling. Plos One. 8: e83110. PMID 24349440 DOI: 10.1371/Journal.Pone.0083110  0.57
2013 Minde DP, Radli M, Forneris F, Maurice MM, Rüdiger SG. Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations. Plos One. 8: e77257. PMID 24130866 DOI: 10.1371/Journal.Pone.0077257  0.414
2013 Peng WC, de Lau W, Forneris F, Granneman JC, Huch M, Clevers H, Gros P. Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5. Cell Reports. 3: 1885-92. PMID 23809763 DOI: 10.1016/J.Celrep.2013.06.009  0.564
2013 Forneris F, Gros P. Complement Factor D Handbook of Proteolytic Enzymes. 3: 2841-2848. DOI: 10.1016/B978-0-12-382219-2.00630-X  0.43
2012 Hadders MA, Bubeck D, Roversi P, Hakobyan S, Forneris F, Morgan BP, Pangburn MK, Llorca O, Lea SM, Gros P. Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9. Cell Reports. 1: 200-7. PMID 22832194 DOI: 10.1016/J.Celrep.2012.02.003  0.546
2012 Forneris F, Wu J, Gros P. The modular serine proteases of the complement cascade. Current Opinion in Structural Biology. 22: 333-41. PMID 22560446 DOI: 10.1016/J.Sbi.2012.04.001  0.588
2012 Forneris F, Hadders MA, Wu J, Gros P. Modularity and conformational changes as key features of the complement system Acta Crystallographica Section a Foundations of Crystallography. 68: s32-s32. DOI: 10.1107/S0108767312099394  0.513
2011 Forneris F, Ricklin D, Wu J, Tzekou A, Wallace RS, Lambris JD, Gros P. Complement convertase formation based on the structures of C3b in complex with factors B and D Acta Crystallographica Section a Foundations of Crystallography. 67: C23-C24. DOI: 10.1107/S0108767311099545  0.545
2011 Gros P, Forneris F, Hadders M, Wu J. Mechanistic insights into the complement system Acta Crystallographica Section a Foundations of Crystallography. 67: C118-C119. DOI: 10.1107/S0108767311097108  0.543
2010 Forneris F, Ricklin D, Wu J, Tzekou A, Wallace RS, Lambris JD, Gros P. Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science (New York, N.Y.). 330: 1816-20. PMID 21205667 DOI: 10.1126/Science.1195821  0.562
2010 Binda C, Valente S, Romanenghi M, Pilotto S, Cirilli R, Karytinos A, Ciossani G, Botrugno OA, Forneris F, Tardugno M, Edmondson DE, Minucci S, Mattevi A, Mai A. Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2. Journal of the American Chemical Society. 132: 6827-33. PMID 20415477 DOI: 10.1021/Ja101557K  0.634
2010 Zibetti C, Adamo A, Binda C, Forneris F, Toffolo E, Verpelli C, Ginelli E, Mattevi A, Sala C, Battaglioli E. Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2521-32. PMID 20164337 DOI: 10.1523/Jneurosci.5500-09.2010  0.596
2010 Forneris F, Wu J, Wallace RS, Tzekou A, Ricklin D, Lambris JD, Gros P. Crystal structure of C3bB in complex with factor D Molecular Immunology. 47: 2259-2260. DOI: 10.1016/J.Molimm.2010.05.186  0.552
2009 Villa F, Capasso P, Tortorici M, Forneris F, de Marco A, Mattevi A, Musacchio A. Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization. Proceedings of the National Academy of Sciences of the United States of America. 106: 20204-9. PMID 19918049 DOI: 10.1073/Pnas.0908485106  0.581
2009 Forneris F, Battaglioli E, Mattevi A, Binda C. New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin. The Febs Journal. 276: 4304-12. PMID 19624733 DOI: 10.1111/J.1742-4658.2009.07142.X  0.652
2009 Baron R, Riley C, Chenprakhon P, Thotsaporn K, Winter RT, Alfieri A, Forneris F, van Berkel WJ, Chaiyen P, Fraaije MW, Mattevi A, McCammon JA. Multiple pathways guide oxygen diffusion into flavoenzyme active sites. Proceedings of the National Academy of Sciences of the United States of America. 106: 10603-8. PMID 19541622 DOI: 10.1073/Pnas.0903809106  0.569
2009 Forneris F, Orru R, Bonivento D, Chiarelli LR, Mattevi A. ThermoFAD, a Thermofluor-adapted flavin ad hoc detection system for protein folding and ligand binding. The Febs Journal. 276: 2833-40. PMID 19459938 DOI: 10.1111/J.1742-4658.2009.07006.X  0.582
2009 Karytinos A, Forneris F, Profumo A, Ciossani G, Battaglioli E, Binda C, Mattevi A. A novel mammalian flavin-dependent histone demethylase. The Journal of Biological Chemistry. 284: 17775-82. PMID 19407342 DOI: 10.1074/Jbc.M109.003087  0.634
2008 Forneris F, Mattevi A. Enzymes without borders: mobilizing substrates, delivering products. Science (New York, N.Y.). 321: 213-6. PMID 18621661 DOI: 10.1126/Science.1151118  0.579
2008 Forneris F, Binda C, Battaglioli E, Mattevi A. LSD1: oxidative chemistry for multifaceted functions in chromatin regulation. Trends in Biochemical Sciences. 33: 181-9. PMID 18343668 DOI: 10.1016/J.Tibs.2008.01.003  0.628
2008 Forneris F, Heuts DPHM, Delvecchio M, Rovida S, Fraaije MW, Mattevi A. Structural analysis of the catalytic mechanism and stereoselectivity in Streptomyces coelicolor alditol oxidase Biochemistry. 47: 978-985. PMID 18154360 DOI: 10.1021/Bi701886T  0.63
2008 Mattevi A, Forneris F, Edmondson D, Binda C. Monoamine oxidases and LSD1: similar chemistry for neurotransmitter and chromatin modification Acta Crystallographica Section a Foundations of Crystallography. 64: C37-C38. DOI: 10.1107/S0108767308098814  0.589
2007 Forneris F, Binda C, Adamo A, Battaglioli E, Mattevi A. Structural basis of LSD1-CoREST selectivity in histone H3 recognition. The Journal of Biological Chemistry. 282: 20070-4. PMID 17537733 DOI: 10.1074/Jbc.C700100200  0.638
2006 Forneris F, Binda C, Vanoni M, Mattevi A, Battagliol E. 8 Demethylation pathways for histone methyllysine residues. The Enzymes. 24: 229-42. PMID 26718042 DOI: 10.1016/S1874-6047(06)80010-7  0.622
2006 Forneris F, Rovida S, Heuts DP, Fraaije MW, Mattevi A. Crystallization and preliminary X-ray analysis of an alditol oxidase from Streptomyces coelicolor A3(2). Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1298-300. PMID 17142922 DOI: 10.1107/S1744309106051128  0.525
2006 Forneris F, Binda C, Dall'Aglio A, Fraaije MW, Battaglioli E, Mattevi A. A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1. The Journal of Biological Chemistry. 281: 35289-95. PMID 16987819 DOI: 10.1074/Jbc.M607411200  0.604
2005 Forneris F, Binda C, Vanoni MA, Battaglioli E, Mattevi A. Human histone demethylase LSD1 reads the histone code. The Journal of Biological Chemistry. 280: 41360-5. PMID 16223729 DOI: 10.1074/Jbc.M509549200  0.608
2005 Forneris F, Binda C, Vanoni MA, Mattevi A, Battaglioli E. Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process. Febs Letters. 579: 2203-7. PMID 15811342 DOI: 10.1016/J.Febslet.2005.03.015  0.595
2003 Di Costanzo L, Forneris F, Geremia S, Randaccio L. Phasing protein structures using the group-subgroup relation. Acta Crystallographica. Section D, Biological Crystallography. 59: 1435-9. PMID 12876346 DOI: 10.1107/S0907444903012538  0.669
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