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James E. Rothman - Publications

Affiliations: 
1978-1988 Biochemistry Stanford University, Palo Alto, CA 
 1988-1991 Molecular Biology Princeton University, Princeton, NJ 
 1991-2004 Cellular Biochemistry and Biophysics Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States 
 2004-2008 Cellular Biophysics Columbia University, New York, NY 
 2008- Cell Biology Yale University, New Haven, CT 
Area:
Secretion, membrane fusion
Website:
https://www.nobelprize.org/nobel_prizes/medicine/laureates/2013/rothman-bio.html
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Year Citation  Score
2024 Schueder F, Rivera-Molina F, Su M, Marin Z, Kidd P, Rothman JE, Toomre D, Bewersdorf J. Unraveling cellular complexity with transient adapters in highly multiplexed super-resolution imaging. Cell. 187: 1769-1784.e18. PMID 38552613 DOI: 10.1016/j.cell.2024.02.033  0.548
2024 Brown C, Ghosh S, McAllister R, Kumar M, Walker G, Sun E, Aman T, Panda A, Kumar S, Li W, Coleman J, Liu Y, Rothman JE, Bhatacharyya M, Gupta K. A proteome-wide quantitative guide for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs. Biorxiv : the Preprint Server For Biology. PMID 38405833 DOI: 10.1101/2024.02.10.579775  0.352
2023 Bera M, Radhakrishnan A, Coleman J, K Sundaram RV, Ramakrishnan S, Pincet F, Rothman JE. Synaptophysin chaperones the assembly of 12 SNAREpins under each ready-release vesicle. Proceedings of the National Academy of Sciences of the United States of America. 120: e2311484120. PMID 37903271 DOI: 10.1073/pnas.2311484120  0.786
2023 Rothman JE, Grushin K, Bera M, Pincet F. Turbocharging synaptic transmission. Febs Letters. 597: 2233-2249. PMID 37643878 DOI: 10.1002/1873-3468.14718  0.305
2023 Kalyana Sundaram RV, Chatterjee A, Bera M, Grushin K, Panda A, Li F, Coleman J, Lee S, Ramakrishnan S, Ernst AM, Gupta K, Rothman JE, Krishnakumar SS. Roles for diacylglycerol in synaptic vesicle priming and release revealed by complete reconstitution of core protein machinery. Proceedings of the National Academy of Sciences of the United States of America. 120: e2309516120. PMID 37590407 DOI: 10.1073/pnas.2309516120  0.739
2023 Bera M, Grushin K, Sundaram RVK, Shahanoor Z, Chatterjee A, Radhakrishnan A, Lee S, Padmanarayana M, Coleman J, Pincet F, Rothman JE, Dittman JS. Two successive oligomeric Munc13 assemblies scaffold vesicle docking and SNARE assembly to support neurotransmitter release. Biorxiv : the Preprint Server For Biology. PMID 37503179 DOI: 10.1101/2023.07.14.549017  0.739
2023 Bera M, Radhakrishnan A, Coleman J, Sundaram RVK, Ramakrishnan S, Pincet F, Rothman JE. Synaptophysin Chaperones the Assembly of 12 SNAREpins under each Ready-Release Vesicle. Biorxiv : the Preprint Server For Biology. PMID 37461465 DOI: 10.1101/2023.07.05.547834  0.768
2023 Sundaram RVK, Chatterjee A, Bera M, Grushin K, Panda A, Li F, Coleman J, Lee S, Ramakrishnan S, Ernst AM, Gupta K, Rothman JE, Krishnakumar SS. Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery. Biorxiv : the Preprint Server For Biology. PMID 37333317 DOI: 10.1101/2023.06.05.543781  0.739
2023 Panda A, Giska F, Duncan AL, Welch AJ, Brown C, McAllister R, Hariharan P, Goder JND, Coleman J, Ramakrishnan S, Pincet F, Guan L, Krishnakumar S, Rothman JE, Gupta K. Direct determination of oligomeric organization of integral membrane proteins and lipids from intact customizable bilayer. Nature Methods. PMID 37106230 DOI: 10.1038/s41592-023-01864-5  0.764
2022 Rothman JE. The gripping story of integrins. Cell. PMID 36174578 DOI: 10.1016/j.cell.2022.09.017  0.235
2022 Zhu J, McDargh ZA, Li F, Krishnakumar SS, Rothman JE, O'Shaughnessy B. Synaptotagmin rings as high-sensitivity regulators of synaptic vesicle docking and fusion. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208337119. PMID 36103579 DOI: 10.1073/pnas.2208337119  0.437
2022 Bera M, Ramakrishnan S, Coleman J, Krishnakumar SS, Rothman JE. Molecular determinants of complexin clamping and activation function. Elife. 11. PMID 35442188 DOI: 10.7554/eLife.71938  0.764
2022 Grushin K, Kalyana Sundaram RV, Sindelar CV, Rothman JE. Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35135883 DOI: 10.1073/pnas.2121259119  0.374
2021 François-Martin C, Bacle A, Rothman JE, Fuchs PFJ, Pincet F. Cooperation of Conical and Polyunsaturated Lipids to Regulate Initiation and Processing of Membrane Fusion. Frontiers in Molecular Biosciences. 8: 763115. PMID 34746239 DOI: 10.3389/fmolb.2021.763115  0.427
2021 Li F, Kalyana Sundaram V, Gatta AT, Coleman J, Ramakrishnan S, Krishnakumar SS, Pincet F, Rothman JE. Vesicle capture by membrane-bound Munc13-1 requires self-assembly into discrete clusters. Febs Letters. PMID 34227103 DOI: 10.1002/1873-3468.14157  0.766
2021 Hao X, Allgeyer ES, Lee DR, Antonello J, Watters K, Gerdes JA, Schroeder LK, Bottanelli F, Zhao J, Kidd P, Lessard MD, Rothman JE, Cooley L, Biederer T, Booth MJ, et al. Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution. Nature Methods. PMID 34059828 DOI: 10.1038/s41592-021-01149-9  0.552
2021 Heo P, Coleman J, Fleury JB, Rothman JE, Pincet F. Nascent fusion pore opening monitored at single-SNAREpin resolution. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33495324 DOI: 10.1073/pnas.2024922118  0.437
2021 Radhakrishnan A, Li X, Grushin K, Krishnakumar SS, Liu J, Rothman JE. Symmetrical arrangement of proteins under release-ready vesicles in presynaptic terminals. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33468631 DOI: 10.1073/pnas.2024029118  0.425
2020 Kalyana Sundaram RV, Jin H, Li F, Shu T, Coleman J, Yang J, Pincet F, Zhang Y, Rothman JE, Krishnakumar SS. Munc13 binds and recruits SNAP25 to chaperone SNARE complex assembly. Febs Letters. PMID 33222163 DOI: 10.1002/1873-3468.14006  0.451
2020 Gruget C, Bello O, Coleman J, Krishnakumar SS, Perez E, Rothman JE, Pincet F, Donaldson SH. Synaptotagmin-1 membrane binding is driven by the C2B domain and assisted cooperatively by the C2A domain. Scientific Reports. 10: 18011. PMID 33093513 DOI: 10.1038/s41598-020-74923-y  0.357
2020 Ziltener P, Rebane AA, Graham M, Ernst AM, Rothman JE. The golgin family exhibits a propensity to form condensates in living cells. Febs Letters. PMID 32668013 DOI: 10.1002/1873-3468.13884  0.65
2020 Raote I, Ernst AM, Campelo F, Rothman JE, Pincet F, Malhotra V. TANGO1 membrane helices create a lipid diffusion barrier at curved membranes. Elife. 9. PMID 32452385 DOI: 10.7554/Elife.57822  0.769
2020 Rothman JE. A tribute to Paul A. Marks, MD, 1926-2020. The Journal of Clinical Investigation. PMID 32420914 DOI: 10.1172/JCI140020  0.185
2020 Ramakrishnan S, Bera M, Coleman J, Rothman JE, Krishnakumar SS. Synergistic roles of Synaptotagmin-1 and complexin in calcium-regulated neuronal exocytosis. Elife. 9. PMID 32401194 DOI: 10.7554/Elife.54506  0.789
2020 Tagliatti E, Bello OD, Mendonça PRF, Kotzadimitriou D, Nicholson E, Coleman J, Timofeeva Y, Rothman JE, Krishnakumar SS, Volynski KE. Synaptotagmin 1 oligomers clamp and regulate different modes of neurotransmitter release. Proceedings of the National Academy of Sciences of the United States of America. PMID 32015138 DOI: 10.1073/pnas.1920403117  0.407
2020 Zhang Y, Schroeder LK, Lessard MD, Kidd P, Chung J, Song Y, Benedetti L, Li Y, Ries J, Grimm JB, Lavis LD, De Camilli P, Rothman JE, Baddeley D, Bewersdorf J. Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging. Nature Methods. PMID 31907447 DOI: 10.1038/S41592-019-0676-4  0.626
2020 Raote I, Ernst AM, Campelo F, Rothman JE, Pincet F, Malhotra V. Author response: TANGO1 membrane helices create a lipid diffusion barrier at curved membranes Elife. DOI: 10.7554/Elife.57822.Sa2  0.632
2020 Ramakrishnan S, Bera M, Coleman J, Rothman JE, Krishnakumar SS. Author response: Synergistic roles of Synaptotagmin-1 and complexin in calcium-regulated neuronal exocytosis Elife. DOI: 10.7554/Elife.54506.Sa2  0.708
2020 Heo P, Rothman J, Pincet F. In vitro physiological membrane‐on‐a‐chip and its application in cell and neuronal biology The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08637  0.331
2020 Ramakrishnan S, Bera M, Coleman J, Pincet F, Rothman J, Krishnakumar SS. Dissecting the Synergistic Roles of Synaptotagmin and Complexin in Ca2+-Regulated Exocytosis Biophysical Journal. 118: 488a. DOI: 10.1016/J.Bpj.2019.11.2702  0.717
2020 Sundaram RVK, Li F, Coleman J, Pincet F, Rothman J, Krishnakumar SS. Munc13 Recruits SNAP25 to Facilitate SNARE Complex Assembly Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.2274  0.414
2020 Zhang Y, Shu T, Rothman J. Munc13-1 and Munc18-1 Cooperatively Chaperone SNARE Assembly through a Tetrameric Complex Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.2273  0.405
2020 Grushin KS, Sundaram RVK, Gibson K, Krishnakumar SS, Sindelar CV, Rothman J. In Vitro Configuration of Munc13-1 Bridging of Phospholipid Bilayers at Resting Conditions Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.2272  0.392
2020 Li F, Sundaram RVK, Coleman J, Krishnakumar SS, Pincet F, Rothman J. Munc13 Clusters Capture Vesicles to Lipid Bilayer Membrane Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1990  0.478
2019 Shu T, Jin H, Rothman JE, Zhang Y. Munc13-1 MUN domain and Munc18-1 cooperatively chaperone SNARE assembly through a tetrameric complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 31888993 DOI: 10.1073/Pnas.1914361117  0.53
2019 Rebane AA, Ziltener P, LaMonica LC, Bauer AH, Zheng H, López-Montero I, Pincet F, Rothman JE, Ernst AM. Liquid-Liquid Phase Separation of the Golgi Matrix Protein GM130. Febs Letters. PMID 31833055 DOI: 10.1002/1873-3468.13715  0.707
2019 Rothman JE. Jim's View: Is the Golgi stack a phase-separated liquid crystal? Febs Letters. PMID 31562650 DOI: 10.1002/1873-3468.13609  0.313
2019 Tiwari N, Graham M, Liu X, Yue X, Zhu L, Meshram D, Choi S, Qian Y, Rothman JE, Lee I. Golgin45-Syntaxin5 Interaction Contributes to Structural Integrity of the Golgi Stack. Scientific Reports. 9: 12465. PMID 31462665 DOI: 10.1038/s41598-019-48875-x  0.485
2019 Rothman JE. Jim's view: Why basic science? Febs Letters. PMID 31301070 DOI: 10.1002/1873-3468.13510  0.307
2019 Rothman JE. Jim's view: What makes transformative basic science possible? Febs Letters. PMID 31301063 DOI: 10.1002/1873-3468.13517  0.314
2019 Rothman JE. Jim's view: Patience vs urgency. Febs Letters. PMID 31301062 DOI: 10.1002/1873-3468.13518  0.306
2019 Salpietro V, Dixon CL, Guo H, Bello OD, Vandrovcova J, Efthymiou S, Maroofian R, Heimer G, Burglen L, Valence S, Torti E, Hacke M, Rankin J, Tariq H, Colin E, ... ... Rothman JE, et al. AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders. Nature Communications. 10: 3094. PMID 31300657 DOI: 10.1038/S41467-019-10910-W  0.368
2019 Chelban V, Wilson MP, Warman Chardon J, Vandrovcova J, Zanetti MN, Zamba-Papanicolaou E, Efthymiou S, Pope S, Conte MR, Abis G, Liu YT, Tribollet E, Haridy NA, Botía JA, Ryten M, ... ... Rothman JE, et al. PDXK mutations cause polyneuropathy responsive to PLP supplementation. Annals of Neurology. PMID 31187503 DOI: 10.1002/ana.25524  0.315
2019 Grushin K, Wang J, Coleman J, Rothman JE, Sindelar CV, Krishnakumar SS. Structural basis for the clamping and Ca activation of SNARE-mediated fusion by synaptotagmin. Nature Communications. 10: 2413. PMID 31160571 DOI: 10.1038/s41467-019-10391-x  0.535
2019 Heo P, Ramakrishnan S, Coleman J, Rothman JE, Fleury JB, Pincet F. Highly Reproducible Physiological Asymmetric Membrane with Freely Diffusing Embedded Proteins in a 3D-Printed Microfluidic Setup. Small (Weinheim An Der Bergstrasse, Germany). e1900725. PMID 30977975 DOI: 10.1002/Smll.201900725  0.781
2019 Salpietro V, Malintan NT, Llano-Rivas I, Spaeth CG, Efthymiou S, Striano P, Vandrovcova J, Cutrupi MC, Chimenz R, David E, Di Rosa G, Marce-Grau A, Raspall-Chaure M, Martin-Hernandez E, Zara F, ... ... Rothman JE, et al. Mutations in the Neuronal Vesicular SNARE VAMP2 Affect Synaptic Membrane Fusion and Impair Human Neurodevelopment. American Journal of Human Genetics. PMID 30929742 DOI: 10.1016/J.Ajhg.2019.02.016  0.486
2019 Erdmann RS, Baguley SW, Richens JH, Wissner RF, Xi Z, Allgeyer ES, Zhong S, Thompson AD, Lowe N, Butler R, Bewersdorf J, Rothman JE, St Johnston D, Schepartz A, Toomre D. Labeling Strategies Matter for Super-Resolution Microscopy: A Comparison between HaloTags and SNAP-tags. Cell Chemical Biology. PMID 30745239 DOI: 10.1016/J.Chembiol.2019.01.003  0.629
2019 Manca F, Pincet F, Truskinovsky L, Rothman JE, Foret L, Caruel M. SNARE machinery is optimized for ultrafast fusion. Proceedings of the National Academy of Sciences of the United States of America. PMID 30700546 DOI: 10.1073/Pnas.1820394116  0.52
2019 Chelban V, Wilson MP, Chardon JW, Vandrovcova J, Zanetti MN, Zamba-Papanicolaou E, Efthymiou S, Pope S, Conte MR, Abis G, Liu Y, Tribollet E, Haridy NA, Botía JA, Ryten M, ... ... Rothman JE, et al. 15.09 Inherited peripheral neuropathies: analysis of PDXK gene identifies a new treatable disorder Journal of Neurology, Neurosurgery, and Psychiatry. 90. DOI: 10.1136/Jnnp-2019-Abn-2.216  0.367
2019 Montesano R, Schekman R, Rothman J, Perrelet A. In Memoriam: Lelio Orci, 1937–2019 Proceedings of the National Academy of Sciences. 117: 15-17. DOI: 10.1073/Pnas.1920094117  0.576
2018 Ramakrishnan S, Bera M, Coleman J, Krishnakumar SS, Pincet F, Rothman JE. Synaptotagmin oligomers are necessary and can be sufficient to form a Ca -sensitive fusion clamp. Febs Letters. PMID 30570144 DOI: 10.1002/1873-3468.13317  0.777
2018 Li X, Radhakrishnan A, Grushin K, Kasula R, Chaudhuri A, Gomathinayagam S, Krishnakumar SS, Liu J, Rothman JE. Symmetrical Organization of Proteins Under Docked Synaptic-Vesicles. Febs Letters. PMID 30561792 DOI: 10.1002/1873-3468.13316  0.529
2018 Rothman JE. Jim's view: analog to digital conversion in biology. Febs Letters. 592: 4009-4010. PMID 30552677 DOI: 10.1002/1873-3468.13308  0.315
2018 Ernst AM, Syed SA, Zaki O, Bottanelli F, Zheng H, Hacke M, Xi Z, Rivera-Molina F, Graham M, Rebane AA, Björkholm P, Baddeley D, Toomre D, Pincet F, Rothman JE. S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi. Developmental Cell. 47: 479-493.e7. PMID 30458139 DOI: 10.1016/J.Devcel.2018.10.024  0.728
2018 Karatekin E, Rothman JE. FEBS Letters Special Issue on Exocytosis and Endocytosis. Febs Letters. 592: 3477-3479. PMID 30417372 DOI: 10.1002/1873-3468.13274  0.654
2018 Kilian N, Goryaynov A, Lessard MD, Hooker G, Toomre D, Rothman JE, Bewersdorf J. Assessing photodamage in live-cell STED microscopy. Nature Methods. 15: 755-756. PMID 30275592 DOI: 10.1038/S41592-018-0145-5  0.594
2018 Bello OD, Jouannot O, Chaudhuri A, Stroeva E, Coleman J, Volynski KE, Rothman JE, Krishnakumar SS. Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30038018 DOI: 10.1073/Pnas.1808792115  0.447
2018 Rothman JE. Jim's View: "Playing Billiards with Science". Febs Letters. PMID 29920662 DOI: 10.1002/1873-3468.13125  0.308
2018 Ramakrishnan S, Gohlke A, Li F, Coleman J, Xu W, Rothman JE, Pincet F. High-Throughput Monitoring of Single Vesicle Fusion Using Freestanding Membranes and Automated Analysis. Langmuir : the Acs Journal of Surfaces and Colloids. 34: 5849-5859. PMID 29694054 DOI: 10.1021/Acs.Langmuir.8B00116  0.818
2018 Gruget C, Coleman J, Bello O, Krishnakumar SS, Perez E, Rothman JE, Pincet F, Donaldson SH. Rearrangements under confinement lead to increased binding energy of Synaptotagmin-1 with anionic membranes in Mg and Ca. Febs Letters. 592: 1497-1506. PMID 29578584 DOI: 10.1002/1873-3468.13040  0.453
2018 Coleman J, Jouannot O, Ramakrishnan SK, Zanetti MN, Wang J, Salpietro V, Houlden H, Rothman JE, Krishnakumar SS. PRRT2 Regulates Synaptic Fusion by Directly Modulating SNARE Complex Assembly. Cell Reports. 22: 820-831. PMID 29346777 DOI: 10.1016/j.celrep.2017.12.056  0.776
2018 Rothman JE. Jim's View: "Some Thoughts for Young Scientists". Febs Letters. 592: 461-462. PMID 29336035 DOI: 10.1002/1873-3468.12960  0.309
2018 Rebane AA, Wang B, Ma L, Qu H, Coleman J, Krishnakumar S, Rothman JE, Zhang Y. Two Disease-Causing SNAP-25B Mutations Selectively Impair SNARE C-terminal Assembly. Journal of Molecular Biology. 430: 479-490. PMID 29056461 DOI: 10.1016/J.Jmb.2017.10.012  0.494
2018 Gruget C, Coleman J, Bello O, Krishnakumar S, Pincet F, Rothman JE, Donaldson SH. Direct Measurement of Site-Specific Binding Energetics of Synaptotagmin-1 with Anionic Lipid Membranes Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.3318  0.465
2018 Grushin K, Wang J, Coleman J, Rothman JE, Sindelar CV, Krishnakumar SS. Structural Insight into the Interaction of Synaptotagmin-1 and Snare Complex on Lipid Bilayer by Cryo-Electron Microscopy Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1622  0.406
2017 Michalski N, Goutman JD, Auclair SM, Boutet de Monvel J, Tertrais M, Emptoz A, Parrin A, Nouaille S, Guillon M, Sachse M, Ciric D, Bahloul A, Hardelin JP, Sutton RB, Avan P, ... ... Rothman JE, et al. Otoferlin acts as a Ca sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses. Elife. 6. PMID 29111973 DOI: 10.7554/Elife.31013  0.459
2017 Rothman JE, Krishnakumar SS, Grushin K, Pincet F. Hypothesis - buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission. Febs Letters. 591: 3459-3480. PMID 28983915 DOI: 10.1002/1873-3468.12874  0.453
2017 Praschberger R, Lowe SA, Malintan NT, Giachello CNG, Patel N, Houlden H, Kullmann DM, Baines RA, Usowicz MM, Krishnakumar SS, Hodge JJL, Rothman JE, Jepson JEC. Mutations in Membrin/GOSR2 Reveal Stringent Secretory Pathway Demands of Dendritic Growth and Synaptic Integrity. Cell Reports. 21: 97-109. PMID 28978487 DOI: 10.1016/j.celrep.2017.09.004  0.467
2017 Krishnakumar SS, Li F, Coleman J, Schauder CM, Kümmel D, Pincet F, Rothman JE, Reinisch KM. Correction: Re-visiting the trans insertion model for complexin clamping. Elife. 6. PMID 28880147 DOI: 10.7554/Elife.31512  0.331
2017 Dunlop MH, Ernst AM, Schroeder LK, Toomre DK, Lavieu G, Rothman JE. Land-locked mammalian Golgi reveals cargo transport between stable cisternae. Nature Communications. 8: 432. PMID 28874656 DOI: 10.1038/S41467-017-00570-Z  0.809
2017 Wang J, Li F, Bello OD, Sindelar CV, Pincet F, Krishnakumar SS, Rothman JE. Circular oligomerization is an intrinsic property of synaptotagmin. Elife. 6. PMID 28850328 DOI: 10.7554/eLife.27441  0.469
2017 Yue X, Bao M, Christiano R, Li S, Mei J, Zhu L, Mao F, Yue Q, Zhang P, Jing S, Rothman JE, Qian Y, Lee I. ACBD3 functions as a scaffold to organize the Golgi stacking proteins and a Rab33b-GAP. Febs Letters. 591: 2793-2802. PMID 28777890 DOI: 10.1002/1873-3468.12780  0.492
2017 Takakura H, Zhang Y, Erdmann RS, Thompson AD, Lin Y, McNellis B, Rivera-Molina F, Uno SN, Kamiya M, Urano Y, Rothman JE, Bewersdorf J, Schepartz A, Toomre D. Long time-lapse nanoscopy with spontaneously blinking membrane probes. Nature Biotechnology. 35: 773-780. PMID 28671662 DOI: 10.1038/Nbt.3876  0.676
2017 Chelban V, Patel N, Vandrovcova J, Zanetti MN, Lynch DS, Ryten M, Botía JA, Bello O, Tribollet E, Efthymiou S, Davagnanam I, Bashiri FA, Wood NW, Rothman JE, et al. Mutations in NKX6-2 Cause Progressive Spastic Ataxia and Hypomyelination. American Journal of Human Genetics. 100: 969-977. PMID 28575651 DOI: 10.1016/j.ajhg.2017.05.009  0.328
2017 Mostafavi H, Thiyagarajan S, Stratton BS, Karatekin E, Warner JM, Rothman JE, O'Shaughnessy B. Entropic forces drive self-organization and membrane fusion by SNARE proteins. Proceedings of the National Academy of Sciences of the United States of America. 114: 5455-5460. PMID 28490503 DOI: 10.1073/Pnas.1611506114  0.741
2017 Bottanelli F, Kilian N, Ernst AM, Rivera-Molina F, Schroeder LK, Kromann EB, Lessard MD, Erdmann RS, Schepartz A, Baddeley D, Bewersdorf J, Toomre D, Rothman JE. A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi. Molecular Biology of the Cell. 28: 1676-1687. PMID 28428254 DOI: 10.1091/Mbc.E16-12-0863  0.769
2017 Salpietro V, Lin W, Delle Vedove A, Storbeck M, Liu Y, Efthymiou S, Manole A, Wiethoff S, Ye Q, Saggar A, McElreavey K, Krishnakumar SS, Pitt M, Bello OD, ... Rothman JE, et al. Homozygous mutations in VAMP1 cause a presynaptic congenital myasthenic syndrome. Annals of Neurology. 81: 597-603. PMID 28253535 DOI: 10.1002/Ana.24905  0.357
2017 François-Martin C, Rothman JE, Pincet F. Low energy cost for optimal speed and control of membrane fusion. Proceedings of the National Academy of Sciences of the United States of America. 114: 1238-1241. PMID 28115718 DOI: 10.1073/pnas.1621309114  0.51
2017 Michalski N, Goutman JD, Auclair SM, Monvel JBd, Tertrais M, Emptoz A, Parrin A, Nouaille S, Guillon M, Sachse M, Ciric D, Bahloul A, Hardelin J, Sutton RB, Avan P, ... ... Rothman JE, et al. Author response: Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses Elife. DOI: 10.7554/Elife.31013.024  0.439
2017 Wang J, Li F, Bello OD, Sindelar CV, Pincet F, Krishnakumar SS, Rothman JE. Author response: Circular oligomerization is an intrinsic property of synaptotagmin Elife. DOI: 10.7554/Elife.27441.019  0.322
2017 Chaudhuri A, Yang Y, Hin Chung KK, Zhang Z, Pincet F, Krishnakumar S, Lin C, Rothman JE, Baddeley D. DNA-Paint Imaging of DNA-Origami Rings Mimicking Biologically Relevant Structures Biophysical Journal. 112: 143a. DOI: 10.1016/J.Bpj.2016.11.786  0.373
2017 Ramakrishnan SK, Gohlke A, Heo P, Rothman J, Pincet F. The Bilat: A Free Standing Lipid Bilayer Microarray Platform for Membrane Fusion Biophysical Journal. 112: 77a. DOI: 10.1016/j.bpj.2016.11.461  0.776
2017 Gruget C, Coleman J, Krishankumar S, Rothman JE, Pincet F, Donaldson S. Synaptotagmin Interactions with Membranes: Measuring the Force of Calcium Triggering of Neurotransmission Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.220  0.556
2016 Zhang X, Rebane AA, Ma L, Li F, Jiao J, Qu H, Pincet F, Rothman JE, Zhang Y. Stability, folding dynamics, and long-range conformational transition of the synaptic t-SNARE complex. Proceedings of the National Academy of Sciences of the United States of America. 113: E8031-E8040. PMID 27911771 DOI: 10.1073/Pnas.1605748113  0.53
2016 Li F, Tiwari N, Rothman JE, Pincet F. Kinetic barriers to SNAREpin assembly in the regulation of membrane docking/priming and fusion. Proceedings of the National Academy of Sciences of the United States of America. 113: 10536-41. PMID 27601655 DOI: 10.1073/pnas.1604000113  0.526
2016 Zanetti MN, Bello OD, Wang J, Coleman J, Cai Y, Sindelar CV, Rothman JE, Krishnakumar SS. Ring-like oligomers of Synaptotagmins and related C2 domain proteins. Elife. 5. PMID 27434670 DOI: 10.7554/Elife.17262  0.48
2016 Huang F, Sirinakis G, Allgeyer ES, Schroeder LK, Duim WC, Kromann EB, Phan T, Rivera-Molina FE, Myers JR, Irnov I, Lessard M, Zhang Y, Handel MA, Jacobs-Wagner C, Lusk CP, ... Rothman JE, et al. Ultra-High Resolution 3D Imaging of Whole Cells. Cell. 166: 1028-1040. PMID 27397506 DOI: 10.1016/J.Cell.2016.06.016  0.612
2016 Pincet F, Adrien V, Yang R, Delacotte J, Rothman JE, Urbach W, Tareste D. FRAP to Characterize Molecular Diffusion and Interaction in Various Membrane Environments. Plos One. 11: e0158457. PMID 27387979 DOI: 10.1371/journal.pone.0158457  0.486
2016 Dancourt J, Zheng H, Bottanelli F, Allgeyer ES, Bewersdorf J, Graham M, Liu X, Rothman JE, Lavieu G. Small cargoes pass through synthetically glued Golgi stacks. Febs Letters. 590: 1675-86. PMID 27174538 DOI: 10.1002/1873-3468.12210  0.836
2016 Yang Y, Wang J, Shigematsu H, Xu W, Shih WM, Rothman JE, Lin C. Self-assembly of size-controlled liposomes on DNA nanotemplates. Nature Chemistry. 8: 476-83. PMID 27102682 DOI: 10.1038/Nchem.2472  0.503
2016 Bello OD, Auclair SM, Rothman JE, Krishnakumar SS. Using ApoE Nanolipoprotein Particles To Analyze SNARE-Induced Fusion Pores. Langmuir : the Acs Journal of Surfaces and Colloids. 32: 3015-23. PMID 26972604 DOI: 10.1021/acs.langmuir.6b00245  0.795
2016 Bottanelli F, Kromann EB, Allgeyer ES, Erdmann RS, Wood Baguley S, Sirinakis G, Schepartz A, Baddeley D, Toomre DK, Rothman JE, Bewersdorf J. Two-colour live-cell nanoscale imaging of intracellular targets. Nature Communications. 7: 10778. PMID 26940217 DOI: 10.1038/Ncomms10778  0.683
2016 Xu W, Nathwani B, Lin C, Wang J, Karatekin E, Pincet F, Shih W, Rothman JE. A Programmable DNA Origami Platform to Organize SNAREs for Membrane Fusion. Journal of the American Chemical Society. 138: 4439-47. PMID 26938705 DOI: 10.1021/Jacs.5B13107  0.754
2016 Zanetti MN, Bello OD, Wang J, Coleman J, Cai Y, Sindelar CV, Rothman JE, Krishnakumar SS. Author response: Ring-like oligomers of Synaptotagmins and related C2 domain proteins Elife. DOI: 10.7554/Elife.17262.018  0.391
2016 François-Martin C, Rothman JE, Pincet F. Experimental Measurement of the Activation Energy of Phospholipid Membrane Fusion Biophysical Journal. 110: 520. DOI: 10.1016/J.Bpj.2015.11.2778  0.545
2016 Zhu J, O'Shaughnessy B, Rothman J. Mathematical Modeling Supports the Hypothesis that Synaptotagmin Rings Clamp Fusion Biophysical Journal. 110: 431a. DOI: 10.1016/J.Bpj.2015.11.2327  0.54
2016 Rebane AA, Krishnakumar S, Rothman JE, Zhang Y. Effect of Two Disease-Causing Mutations on the Energetics and Kinetics of SNARE Assembly Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2324  0.505
2015 Xu W, Wang J, Rothman JE, Pincet F. Accelerating SNARE-Mediated Membrane Fusion by DNA-Lipid Tethers. Angewandte Chemie (International Ed. in English). 54: 14388-92. PMID 26439984 DOI: 10.1002/anie.201506844  0.564
2015 Motta I, Gohlke A, Adrien V, Li F, Gardavot H, Rothman JE, Pincet F. Correction to Formation of Giant Unilamellar Proteo-Liposomes by Osmotic Shock. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 9521. PMID 26293386 DOI: 10.1021/acs.langmuir.5b02955  0.35
2015 Rothman JE. [In Process Citation]. Biologie Aujourd'Hui. 209: 63-85. PMID 26115713 DOI: 10.1051/jbio/2015010  0.304
2015 Motta I, Gohlke A, Adrien V, Li F, Gardavot H, Rothman JE, Pincet F. Formation of Giant Unilamellar Proteo-Liposomes by Osmotic Shock. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 7091-9. PMID 26038815 DOI: 10.1021/acs.langmuir.5b01173  0.552
2015 Krishnakumar SS, Li F, Coleman J, Schauder CM, Kümmel D, Pincet F, Rothman JE, Reinisch KM. Re-visiting the trans insertion model for complexin clamping. Elife. 4. PMID 25831964 DOI: 10.7554/Elife.04463  0.412
2015 Zhu J, Rothman JE. Mechanical Model for Self-Assembly of Synaptotagmin on a Lipid Membrane Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2243  0.538
2015 Rothman JE. Commercial speech, commercial use, and the intellectual property quagmire Virginia Law Review. 101: 1929-2009.  0.17
2014 Wang J, Bello O, Auclair SM, Wang J, Coleman J, Pincet F, Krishnakumar SS, Sindelar CV, Rothman JE. Calcium sensitive ring-like oligomers formed by synaptotagmin. Proceedings of the National Academy of Sciences of the United States of America. 111: 13966-71. PMID 25201968 DOI: 10.1073/pnas.1415849111  0.779
2014 Zorman S, Rebane AA, Ma L, Yang G, Molski MA, Coleman J, Pincet F, Rothman JE, Zhang Y. Common intermediates and kinetics, but different energetics, in the assembly of SNARE proteins. Elife. 3: e03348. PMID 25180101 DOI: 10.7554/Elife.03348  0.515
2014 Lavieu G, Dunlop MH, Lerich A, Zheng H, Bottanelli F, Rothman JE. The Golgi ribbon structure facilitates anterograde transport of large cargoes. Molecular Biology of the Cell. 25: 3028-36. PMID 25103235 DOI: 10.1091/Mbc.E14-04-0931  0.804
2014 Rothman JE. The principle of membrane fusion in the cell (Nobel lecture). Angewandte Chemie (International Ed. in English). 53: 12676-94. PMID 25087728 DOI: 10.1002/anie.201402380  0.557
2014 Cho RW, Kümmel D, Li F, Baguley SW, Coleman J, Rothman JE, Littleton JT. Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111: 10317-22. PMID 24982161 DOI: 10.1073/pnas.1409311111  0.482
2014 Li F, Kümmel D, Coleman J, Reinisch KM, Rothman JE, Pincet F. A half-zippered SNARE complex represents a functional intermediate in membrane fusion. Journal of the American Chemical Society. 136: 3456-64. PMID 24533674 DOI: 10.1021/Ja410690M  0.586
2014 Lee I, Tiwari N, Dunlop MH, Graham M, Liu X, Rothman JE. Membrane adhesion dictates Golgi stacking and cisternal morphology. Proceedings of the National Academy of Sciences of the United States of America. 111: 1849-54. PMID 24449908 DOI: 10.1073/Pnas.1323895111  0.564
2014 Krishnakumar SS, Li F, Coleman J, Schauder CM, Kümmel D, Pincet F, Rothman JE, Reinisch KM. Author response: Re-visiting the trans insertion model for complexin clamping Elife. DOI: 10.7554/Elife.04463.010  0.326
2014 Zorman S, Rebane AA, Ma L, Yang G, Molski MA, Coleman J, Pincet F, Rothman JE, Zhang Y. Author response: Common intermediates and kinetics, but different energetics, in the assembly of SNARE proteins Elife. DOI: 10.7554/Elife.03348.023  0.44
2014 Zorman S, Pincet F, Rothman JE, Zhang Y. Comparative Study of the Snares Zippering with Single Molecule Resolution Biophysical Journal. 106: 5-6. DOI: 10.1016/J.Bpj.2013.11.2831  0.554
2014 Rothman JE. Das Prinzip der Membranfusion in der Zelle (Nobel‐Aufsatz) Angewandte Chemie. 126: 12886-12905. DOI: 10.1002/Ange.201402380  0.295
2013 Krishnakumar SS, Kümmel D, Jones SJ, Radoff DT, Reinisch KM, Rothman JE. Conformational dynamics of calcium-triggered activation of fusion by synaptotagmin. Biophysical Journal. 105: 2507-16. PMID 24314081 DOI: 10.1016/J.Bpj.2013.10.029  0.808
2013 Pellett PA, Dietrich F, Bewersdorf J, Rothman JE, Lavieu G. Inter-Golgi transport mediated by COPI-containing vesicles carrying small cargoes. Elife. 2: e01296. PMID 24137546 DOI: 10.7554/eLife.01296  0.831
2013 Thiam AR, Antonny B, Wang J, Delacotte J, Wilfling F, Walther TC, Beck R, Rothman JE, Pincet F. COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function. Proceedings of the National Academy of Sciences of the United States of America. 110: 13244-9. PMID 23901109 DOI: 10.1073/Pnas.1307685110  0.801
2013 Lavieu G, Zheng H, Rothman JE. Stapled Golgi cisternae remain in place as cargo passes through the stack. Elife. 2: e00558. PMID 23755362 DOI: 10.7554/eLife.00558  0.809
2013 Shi L, Howan K, Shen QT, Wang YJ, Rothman JE, Pincet F. Preparation and characterization of SNARE-containing nanodiscs and direct study of cargo release through fusion pores. Nature Protocols. 8: 935-48. PMID 23598444 DOI: 10.1038/Nprot.2013.048  0.505
2013 Pellett PA, Dietrich F, Bewersdorf J, Rothman JE, Lavieu G. Author response: Inter-Golgi transport mediated by COPI-containing vesicles carrying small cargoes Elife. DOI: 10.7554/Elife.01296.018  0.494
2013 Lavieu G, Zheng H, Rothman JE. Author response: Stapled Golgi cisternae remain in place as cargo passes through the stack Elife. DOI: 10.7554/Elife.00558.020  0.361
2013 Gao Y, Zorman S, Gundersen G, Xi Z, Ma L, Sirinakis G, Rothman JE, Zhang Y. Single Neuronal Snare Complexes Zipper in Three Distinct Stages Biophysical Journal. 104: 89a. DOI: 10.1016/J.Bpj.2012.11.531  0.53
2013 Krishnakumar S, Jones S, Kummel D, Rothman J. Calcium Triggered Membrane Penetration of Synaptotagmin may Provide the Driving Force to Reverse the Complexin Clamp Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.2746  0.525
2013 Jones S, Krishnakumar S, Kummel D, Rothman J. Molecular Mechanisms of Synchronous Synaptic Transmission Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.2745  0.53
2013 Rothman J. Control of Membrane Fusion in Exocytosis Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.089  0.536
2013 Rothman JE. E-sports as a prism for the role of evolving technology in intellectual property University of Pennsylvania Law Review. 161: 317-329.  0.174
2012 Gao Y, Zorman S, Gundersen G, Xi Z, Ma L, Sirinakis G, Rothman JE, Zhang Y. Single reconstituted neuronal SNARE complexes zipper in three distinct stages. Science (New York, N.Y.). 337: 1340-3. PMID 22903523 DOI: 10.1126/Science.1224492  0.529
2012 Karatekin E, Rothman JE. Fusion of single proteoliposomes with planar, cushioned bilayers in microfluidic flow cells. Nature Protocols. 7: 903-20. PMID 22517259 DOI: 10.1038/Nprot.2012.019  0.728
2012 Shi L, Shen QT, Kiel A, Wang J, Wang HW, Melia TJ, Rothman JE, Pincet F. SNARE proteins: one to fuse and three to keep the nascent fusion pore open. Science (New York, N.Y.). 335: 1355-9. PMID 22422984 DOI: 10.1126/Science.1214984  0.576
2012 Rothman JE. Copyright, custom, and lessons from the common law Intellectual Property and the Common Law. 230-251. DOI: 10.1017/CBO9781139013550.013  0.185
2012 Rothman JE. The inalienable right of publicity Georgetown Law Journal. 101: 185-241.  0.182
2011 Rothman JE, Schekman R. Molecular mechanism of protein folding in the cell. Cell. 146: 851-4. PMID 21907398 DOI: 10.1016/J.Cell.2011.08.041  0.596
2011 Pellett PA, Sun X, Gould TJ, Rothman JE, Xu MQ, Corrêa IR, Bewersdorf J. Two-color STED microscopy in living cells. Biomedical Optics Express. 2: 2364-71. PMID 21833373 DOI: 10.1364/Boe.2.002364  0.604
2011 Kümmel D, Krishnakumar SS, Radoff DT, Li F, Giraudo CG, Pincet F, Rothman JE, Reinisch KM. Complexin cross-links prefusion SNAREs into a zigzag array. Nature Structural & Molecular Biology. 18: 927-33. PMID 21785414 DOI: 10.1038/Nsmb.2101  0.82
2011 Li F, Pincet F, Perez E, Giraudo CG, Tareste D, Rothman JE. Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state. Nature Structural & Molecular Biology. 18: 941-6. PMID 21785413 DOI: 10.1038/nsmb.2102  0.543
2011 Krishnakumar SS, Radoff DT, Kümmel D, Giraudo CG, Li F, Khandan L, Baguley SW, Coleman J, Reinisch KM, Pincet F, Rothman JE. A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion. Nature Structural & Molecular Biology. 18: 934-40. PMID 21785412 DOI: 10.1038/Nsmb.2103  0.8
2011 Cremona ML, Matthies HJ, Pau K, Bowton E, Speed N, Lute BJ, Anderson M, Sen N, Robertson SD, Vaughan RA, Rothman JE, Galli A, Javitch JA, Yamamoto A. Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT. Nature Neuroscience. 14: 469-77. PMID 21399631 DOI: 10.1038/Nn.2781  0.658
2011 Cremona ML, Matthies HJG, Pau K, Bowton E, Speed N, Lute BJ, Anderson M, Sen N, Robertson SD, Vaughan RA, Rothman JE, Galli A, Javitch JA, Yamamoto A. Erratum: Corrigendum: Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT Nature Neuroscience. 14: 1617-1617. DOI: 10.1038/Nn1211-1617A  0.645
2011 Karatekin E, Gohlke A, Smith M, Vavylonis D, Rothman JE. Visualizing Release of Single Fluorophores at Membrane Fusion Sites Biophysical Journal. 100: 185a. DOI: 10.1016/J.Bpj.2010.12.1230  0.725
2010 Rothman J, Scheller R, Südhof T. An interview with the Kavli prize winners. Interview by Claudia Wiedemann. Nature Reviews. Neuroscience. 11: 669-73. PMID 21080540 DOI: 10.1038/nrn2900  0.176
2010 Rothman JE. The future of Golgi research. Molecular Biology of the Cell. 21: 3776-80. PMID 21079007 DOI: 10.1091/mbc.E10-05-0418  0.36
2010 Ji H, Coleman J, Yang R, Melia TJ, Rothman JE, Tareste D. Protein determinants of SNARE-mediated lipid mixing. Biophysical Journal. 99: 553-60. PMID 20643074 DOI: 10.1016/j.bpj.2010.04.060  0.556
2010 Shen J, Rathore SS, Khandan L, Rothman JE. SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion. The Journal of Cell Biology. 190: 55-63. PMID 20603329 DOI: 10.1083/Jcb.201003148  0.535
2010 Lavieu G, Orci L, Shi L, Geiling M, Ravazzola M, Wieland F, Cosson P, Rothman JE. Induction of cortical endoplasmic reticulum by dimerization of a coatomer-binding peptide anchored to endoplasmic reticulum membranes. Proceedings of the National Academy of Sciences of the United States of America. 107: 6876-81. PMID 20351264 DOI: 10.1073/pnas.1002536107  0.813
2010 Karatekin E, Di Giovanni J, Iborra C, Coleman J, O'Shaughnessy B, Seagar M, Rothman JE. A fast, single-vesicle fusion assay mimics physiological SNARE requirements. Proceedings of the National Academy of Sciences of the United States of America. 107: 3517-21. PMID 20133592 DOI: 10.1016/J.Bpj.2009.12.3362  0.741
2010 Rothman JE. Best intentions: Reconsidering best practices statements in the context of fair use and copyright law Journal of the Copyright Society of the U.S.a.. 57: 371-387.  0.181
2010 Rothman JE. Liberating copyright: Thinking beyond free speech Cornell Law Review. 95: 463-534.  0.175
2009 Emr S, Glick BS, Linstedt AD, Lippincott-Schwartz J, Luini A, Malhotra V, Marsh BJ, Nakano A, Pfeffer SR, Rabouille C, Rothman JE, Warren G, Wieland FT. Journeys through the Golgi--taking stock in a new era. The Journal of Cell Biology. 187: 449-53. PMID 19948493 DOI: 10.1083/Jcb.200909011  0.805
2009 Paumet F, Wesolowski J, Garcia-Diaz A, Delevoye C, Aulner N, Shuman HA, Subtil A, Rothman JE. Intracellular bacteria encode inhibitory SNARE-like proteins. Plos One. 4: e7375. PMID 19823575 DOI: 10.1371/Journal.Pone.0007375  0.584
2009 Giraudo CG, Garcia-Diaz A, Eng WS, Chen Y, Hendrickson WA, Melia TJ, Rothman JE. Alternative zippering as an on-off switch for SNARE-mediated fusion. Science (New York, N.Y.). 323: 512-6. PMID 19164750 DOI: 10.1126/Science.1166500  0.594
2009 Südhof TC, Rothman JE. Membrane fusion: grappling with SNARE and SM proteins. Science (New York, N.Y.). 323: 474-7. PMID 19164740 DOI: 10.1126/science.1161748  0.593
2008 Giraudo CG, Garcia-Diaz A, Eng WS, Yamamoto A, Melia TJ, Rothman JE. Distinct domains of complexins bind SNARE complexes and clamp fusion in vitro. The Journal of Biological Chemistry. 283: 21211-9. PMID 18499660 DOI: 10.1074/Jbc.M803478200  0.666
2008 Tareste D, Shen J, Melia TJ, Rothman JE. SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes. Proceedings of the National Academy of Sciences of the United States of America. 105: 2380-5. PMID 18268324 DOI: 10.1073/Pnas.0712125105  0.601
2007 Li F, Pincet F, Perez E, Eng WS, Melia TJ, Rothman JE, Tareste D. Energetics and dynamics of SNAREpin folding across lipid bilayers. Nature Structural & Molecular Biology. 14: 890-6. PMID 17906638 DOI: 10.1038/nsmb1310  0.481
2007 Shen J, Tareste DC, Paumet F, Rothman JE, Melia TJ. Selective activation of cognate SNAREpins by Sec1/Munc18 proteins. Cell. 128: 183-95. PMID 17218264 DOI: 10.1016/J.Cell.2006.12.016  0.576
2007 Rothman JE. The questionable use of custom in intellectual property Virginia Law Review. 93: 1899-1982.  0.19
2006 Mayer T, Jagla B, Wyler MR, Kelly PD, Aulner N, Beard M, Barger G, Többen U, Smith DH, Brandén L, Rothman JE. Cell-based assays using primary endothelial cells to study multiple steps in inflammation. Methods in Enzymology. 414: 266-83. PMID 17110197 DOI: 10.1016/S0076-6879(06)14015-X  0.372
2006 Melia TJ, You D, Tareste DC, Rothman JE. Lipidic antagonists to SNARE-mediated fusion. The Journal of Biological Chemistry. 281: 29597-605. PMID 16887809 DOI: 10.1074/jbc.M601778200  0.568
2006 Giraudo CG, Eng WS, Melia TJ, Rothman JE. A clamping mechanism involved in SNARE-dependent exocytosis. Science (New York, N.Y.). 313: 676-80. PMID 16794037 DOI: 10.1126/science.1129450  0.472
2006 Antinozzi PA, Garcia-Diaz A, Hu C, Rothman JE. Functional mapping of disease susceptibility loci using cell biology. Proceedings of the National Academy of Sciences of the United States of America. 103: 3698-703. PMID 16537450 DOI: 10.1073/pnas.0510521103  0.349
2006 Yamamoto A, Cremona ML, Rothman JE. Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway. The Journal of Cell Biology. 172: 719-31. PMID 16505167 DOI: 10.1083/Jcb.200510065  0.581
2005 Cosson P, Ravazzola M, Varlamov O, Söllner TH, Di Liberto M, Volchuk A, Rothman JE, Orci L. Dynamic transport of SNARE proteins in the Golgi apparatus. Proceedings of the National Academy of Sciences of the United States of America. 102: 14647-52. PMID 16199514 DOI: 10.1073/Pnas.0507394102  0.565
2005 Giraudo CG, Hu C, You D, Slovic AM, Mosharov EV, Sulzer D, Melia TJ, Rothman JE. SNAREs can promote complete fusion and hemifusion as alternative outcomes. The Journal of Cell Biology. 170: 249-60. PMID 16027221 DOI: 10.1083/jcb.200501093  0.442
2005 Jagla B, Aulner N, Kelly PD, Song D, Volchuk A, Zatorski A, Shum D, Mayer T, De Angelis DA, Ouerfelli O, Rutishauser U, Rothman JE. Sequence characteristics of functional siRNAs. Rna (New York, N.Y.). 11: 864-72. PMID 15923373 DOI: 10.1261/Rna.7275905  0.36
2005 Paumet F, Rahimian V, Di Liberto M, Rothman JE. Concerted auto-regulation in yeast endosomal t-SNAREs. The Journal of Biological Chemistry. 280: 21137-43. PMID 15799968 DOI: 10.1074/Jbc.M500841200  0.476
2005 Becker T, Volchuk A, Rothman JE. Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages. Proceedings of the National Academy of Sciences of the United States of America. 102: 4022-6. PMID 15753287 DOI: 10.1073/Pnas.0409219102  0.544
2004 Fix M, Melia TJ, Jaiswal JK, Rappoport JZ, You D, Söllner TH, Rothman JE, Simon SM. Imaging single membrane fusion events mediated by SNARE proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 7311-6. PMID 15123811 DOI: 10.1073/pnas.0401779101  0.596
2004 Fukasawa M, Varlamov O, Eng WS, Söllner TH, Rothman JE. Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation. Proceedings of the National Academy of Sciences of the United States of America. 101: 4815-20. PMID 15044687 DOI: 10.1073/pnas.0401183101  0.577
2004 Paumet F, Rahimian V, Rothman JE. The specificity of SNARE-dependent fusion is encoded in the SNARE motif. Proceedings of the National Academy of Sciences of the United States of America. 101: 3376-80. PMID 14981247 DOI: 10.1073/Pnas.0400271101  0.568
2004 Volchuk A, Ravazzola M, Perrelet A, Eng WS, Di Liberto M, Varlamov O, Fukasawa M, Engel T, Söllner TH, Rothman JE, Orci L. Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack. Molecular Biology of the Cell. 15: 1506-18. PMID 14742712 DOI: 10.1091/Mbc.E03-08-0625  0.483
2004 Varlamov O, Volchuk A, Rahimian V, Doege CA, Paumet F, Eng WS, Arango N, Parlati F, Ravazzola M, Orci L, Söllner TH, Rothman JE. i-SNAREs: inhibitory SNAREs that fine-tune the specificity of membrane fusion. The Journal of Cell Biology. 164: 79-88. PMID 14699088 DOI: 10.1083/Jcb.200307066  0.51
2003 Burri L, Varlamov O, Doege CA, Hofmann K, Beilharz T, Rothman JE, Söllner TH, Lithgow T. A SNARE required for retrograde transport to the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 100: 9873-7. PMID 12893879 DOI: 10.1073/Pnas.1734000100  0.552
2003 Hu C, Ahmed M, Melia TJ, Söllner TH, Mayer T, Rothman JE. Fusion of cells by flipped SNAREs. Science (New York, N.Y.). 300: 1745-9. PMID 12805548 DOI: 10.1126/science.1084909  0.565
2002 Rothman JE. Lasker Basic Medical Research Award. The machinery and principles of vesicle transport in the cell. Nature Medicine. 8: 1059-62. PMID 12357232 DOI: 10.1038/nm770  0.438
2002 Cosson P, Amherdt M, Rothman JE, Orci L. A resident Golgi protein is excluded from peri-Golgi vesicles in NRK cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 12831-4. PMID 12223891 DOI: 10.1073/pnas.192460999  0.529
2002 Melia TJ, Weber T, McNew JA, Fisher LE, Johnston RJ, Parlati F, Mahal LK, Sollner TH, Rothman JE. Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins. The Journal of Cell Biology. 158: 929-40. PMID 12213837 DOI: 10.1083/Jcb.200112081  0.823
2002 Parlati F, Varlamov O, Paz K, McNew JA, Hurtado D, Söllner TH, Rothman JE. Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity. Proceedings of the National Academy of Sciences of the United States of America. 99: 5424-9. PMID 11959998 DOI: 10.1073/Pnas.082100899  0.738
2001 Paumet F, Brügger B, Parlati F, McNew JA, Söllner TH, Rothman JE. A t-SNARE of the endocytic pathway must be activated for fusion. The Journal of Cell Biology. 155: 961-8. PMID 11739407 DOI: 10.1083/Jcb.200104092  0.714
2001 Wimmer C, Hohl TM, Hughes CA, Müller SA, Söllner TH, Engel A, Rothman JE. Molecular mass, stoichiometry, and assembly of 20 S particles. The Journal of Biological Chemistry. 276: 29091-7. PMID 11395481 DOI: 10.1074/Jbc.M011292200  0.636
2001 Rothman JE. Freedom of speech and true threats Harvard Journal of Law and Public Policy. 25: 283-367.  0.163
2000 Pelham HR, Rothman JE. The debate about transport in the Golgi--two sides of the same coin? Cell. 102: 713-9. PMID 11030615 DOI: 10.1016/S0092-8674(00)00060-X  0.56
2000 Sankaranarayanan S, De Angelis D, Rothman JE, Ryan TA. The use of pHluorins for optical measurements of presynaptic activity. Biophysical Journal. 79: 2199-208. PMID 11023924 DOI: 10.1016/S0006-3495(00)76468-X  0.455
2000 Fukuda R, McNew JA, Weber T, Parlati F, Engel T, Nickel W, Rothman JE, Söllner TH. Functional architecture of an intracellular membrane t-SNARE. Nature. 407: 198-202. PMID 11001059 DOI: 10.1038/35025084  0.757
2000 Parlati F, McNew JA, Fukuda R, Miller R, Söllner TH, Rothman JE. Topological restriction of SNARE-dependent membrane fusion. Nature. 407: 194-8. PMID 11001058 DOI: 10.1038/35025076  0.786
2000 McNew JA, Parlati F, Fukuda R, Johnston RJ, Paz K, Paumet F, Söllner TH, Rothman JE. Compartmental specificity of cellular membrane fusion encoded in SNARE proteins. Nature. 407: 153-9. PMID 11001046 DOI: 10.1038/35025000  0.822
2000 Orci L, Amherdt M, Ravazzola M, Perrelet A, Rothman JE. Exclusion of golgi residents from transport vesicles budding from Golgi cisternae in intact cells. The Journal of Cell Biology. 150: 1263-70. PMID 10995433 DOI: 10.1083/jcb.150.6.1263  0.559
2000 Volchuk A, Amherdt M, Ravazzola M, Brügger B, Rivera VM, Clackson T, Perrelet A, Söllner TH, Rothman JE, Orci L. Megavesicles implicated in the rapid transport of intracisternal aggregates across the Golgi stack. Cell. 102: 335-48. PMID 10975524 DOI: 10.1016/S0092-8674(00)00039-8  0.445
2000 Orci L, Ravazzola M, Volchuk A, Engel T, Gmachl M, Amherdt M, Perrelet A, Sollner TH, Rothman JE. Anterograde flow of cargo across the golgi stack potentially mediated via bidirectional "percolating" COPI vesicles. Proceedings of the National Academy of Sciences of the United States of America. 97: 10400-5. PMID 10962035 DOI: 10.1073/Pnas.190292497  0.56
2000 McNew JA, Weber T, Parlati F, Johnston RJ, Melia TJ, Söllner TH, Rothman JE. Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors. The Journal of Cell Biology. 150: 105-17. PMID 10893260 DOI: 10.1083/Jcb.150.1.105  0.818
2000 Castellino F, Boucher PE, Eichelberg K, Mayhew M, Rothman JE, Houghton AN, Germain RN. Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways. The Journal of Experimental Medicine. 191: 1957-64. PMID 10839810 DOI: 10.1084/Jem.191.11.1957  0.438
2000 Weber T, Parlati F, McNew JA, Johnston RJ, Westermann B, Söllner TH, Rothman JE. SNAREpins are functionally resistant to disruption by NSF and alphaSNAP. The Journal of Cell Biology. 149: 1063-72. PMID 10831610 DOI: 10.1083/Jcb.149.5.1063  0.824
2000 Moroi Y, Mayhew M, Trcka J, Hoe MH, Takechi Y, Hartl FU, Rothman JE, Houghton AN. Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70. Proceedings of the National Academy of Sciences of the United States of America. 97: 3485-90. PMID 10725409 DOI: 10.1073/Pnas.97.7.3485  0.354
2000 Brügger B, Nickel W, Weber T, Parlati F, McNew JA, Rothman JE, Söllner T. Putative fusogenic activity of NSF is restricted to a lipid mixture whose coalescence is also triggered by other factors. The Embo Journal. 19: 1272-8. PMID 10716927 DOI: 10.1093/Emboj/19.6.1272  0.731
2000 Rivera VM, Wang X, Wardwell S, Courage NL, Volchuk A, Keenan T, Holt DA, Gilman M, Orci L, Cerasoli F, Rothman JE, Clackson T. Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (New York, N.Y.). 287: 826-30. PMID 10657290 DOI: 10.1126/Science.287.5454.826  0.42
2000 McNew JA, Parlati F, Fukuda R, Johnston RJ, Paz K, Paumet F, Sollner TH, Rothman JE. Compartmental specificity of cellular membrane fusion encoded in snare proteins topological restriction of SNARE-dependent membrane fusion: Topological restriction of SNARE-dependent membrane fusion Chemtracts. 13: 853-858.  0.747
1999 Nickel W, Weber T, McNew JA, Parlati F, Söllner TH, Rothman JE. Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs. Proceedings of the National Academy of Sciences of the United States of America. 96: 12571-6. PMID 10535963 DOI: 10.1073/Pnas.96.22.12571  0.757
1999 Parlati F, Weber T, McNew JA, Westermann B, Söllner TH, Rothman JE. Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain. Proceedings of the National Academy of Sciences of the United States of America. 96: 12565-70. PMID 10535962 DOI: 10.1073/Pnas.96.22.12565  0.72
1999 McNew JA, Weber T, Engelman DM, Söllner TH, Rothman JE. The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion. Molecular Cell. 4: 415-21. PMID 10518222 DOI: 10.1016/S1097-2765(00)80343-3  0.753
1999 Bremser M, Nickel W, Schweikert M, Ravazzola M, Amherdt M, Hughes CA, Söllner TH, Rothman JE, Wieland FT. Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors. Cell. 96: 495-506. PMID 10052452 DOI: 10.1016/S0092-8674(00)80654-6  0.566
1998 Hohl TM, Parlati F, Wimmer C, Rothman JE, Söllner TH, Engelhardt H. Arrangement of subunits in 20 S particles consisting of NSF, SNAPs, and SNARE complexes. Molecular Cell. 2: 539-48. PMID 9844627 DOI: 10.1016/S1097-2765(00)80153-7  0.627
1998 Stamnes M, Schiavo G, Stenbeck G, Söllner TH, Rothman JE. ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles. Proceedings of the National Academy of Sciences of the United States of America. 95: 13676-80. PMID 9811859 DOI: 10.1073/Pnas.95.23.13676  0.673
1998 De Angelis DA, Miesenböck G, Zemelman BV, Rothman JE. PRIM: proximity imaging of green fluorescent protein-tagged polypeptides. Proceedings of the National Academy of Sciences of the United States of America. 95: 12312-6. PMID 9770483 DOI: 10.1073/Pnas.95.21.12312  0.693
1998 Miesenböck G, De Angelis DA, Rothman JE. Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature. 394: 192-5. PMID 9671304 DOI: 10.1038/28190  0.742
1998 Weber T, Zemelman BV, McNew JA, Westermann B, Gmachl M, Parlati F, Söllner TH, Rothman JE. SNAREpins: minimal machinery for membrane fusion. Cell. 92: 759-72. PMID 9529252 DOI: 10.1016/S0092-8674(00)81404-X  0.758
1998 Orci L, Perrelet A, Rothman JE. Vesicles on strings: morphological evidence for processive transport within the Golgi stack. Proceedings of the National Academy of Sciences of the United States of America. 95: 2279-83. PMID 9482876 DOI: 10.1073/pnas.95.5.2279  0.521
1997 Fiedler K, Rothman JE. Sorting determinants in the transmembrane domain of p24 proteins. The Journal of Biological Chemistry. 272: 24739-42. PMID 9312065 DOI: 10.1074/jbc.272.40.24739  0.519
1997 Orci L, Stamnes M, Ravazzola M, Amherdt M, Perrelet A, Söllner TH, Rothman JE. Bidirectional transport by distinct populations of COPI-coated vesicles. Cell. 90: 335-49. PMID 9244307 DOI: 10.1016/S0092-8674(00)80341-4  0.541
1997 McNew JA, Sogaard M, Lampen NM, Machida S, Ye RR, Lacomis L, Tempst P, Rothman JE, Söllner TH. Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport. The Journal of Biological Chemistry. 272: 17776-83. PMID 9211930 DOI: 10.1074/Jbc.272.28.17776  0.752
1997 Rothman JE, Söllner TH. Throttles and dampers: controlling the engine of membrane fusion. Science (New York, N.Y.). 276: 1212-3. PMID 9182331 DOI: 10.1126/science.276.5316.1212  0.528
1997 Paek I, Orci L, Ravazzola M, Erdjument-Bromage H, Amherdt M, Tempst P, Söllner TH, Rothman JE. ERS-24, a mammalian v-SNARE implicated in vesicle traffic between the ER and the Golgi. The Journal of Cell Biology. 137: 1017-28. PMID 9166403 DOI: 10.1083/jcb.137.5.1017  0.472
1997 Miesenböck G, Rothman JE. Patterns of synaptic activity in neural networks recorded by light emission from synaptolucins. Proceedings of the National Academy of Sciences of the United States of America. 94: 3402-7. PMID 9096406 DOI: 10.1073/pnas.94.7.3402  0.704
1997 Schiavo G, Stenbeck G, Rothman JE, Söllner TH. Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proceedings of the National Academy of Sciences of the United States of America. 94: 997-1001. PMID 9023371 DOI: 10.1073/Pnas.94.3.997  0.676
1997 Rothman JE. Machinery and mechanisms of intracellular protein transport and synaptic transmission Biochemical Society Transactions. 25: 377S. DOI: 10.1042/Bst025377S  0.493
1997 Rothman JE. Mechanisms and machinery of intracellular protein transport Faseb Journal. 11: A1012.  0.416
1996 Söllner TH, Rothman JE. Molecular machinery mediating vesicle budding, docking and fusion. Cell Structure and Function. 21: 407-12. PMID 9118248 DOI: 10.1247/Csf.21.407  0.6
1996 Söllner TH, Rothman JE. Molecular machinery mediating vesicle budding, docking and fusion. Experientia. 52: 1021-5. PMID 8988241 DOI: 10.1007/BF01952097  0.599
1996 Rothman JE. Felix Hoppe-Seyler Lecture 1996. Mechanisms of intracellular protein transport. Biological Chemistry. 377: 407-10. PMID 8922273 DOI: 10.1515/Bchm3.1996.377.7-8.407  0.581
1996 Schiavo G, Gu QM, Prestwich GD, Söllner TH, Rothman JE. Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin. Proceedings of the National Academy of Sciences of the United States of America. 93: 13327-32. PMID 8917590 DOI: 10.1073/Pnas.93.23.13327  0.589
1996 Rothman JE. The protein machinery of vesicle budding and fusion. Protein Science : a Publication of the Protein Society. 5: 185-94. PMID 8745395 DOI: 10.1002/pro.5560050201  0.55
1996 Fiedler K, Veit M, Stamnes MA, Rothman JE. Bimodal interaction of coatomer with the p24 family of putative cargo receptors. Science (New York, N.Y.). 273: 1396-9. PMID 8703076 DOI: 10.1126/Science.273.5280.1396  0.457
1996 Veit M, Söllner TH, Rothman JE. Multiple palmitoylation of synaptotagmin and the t-SNARE SNAP-25. Febs Letters. 385: 119-23. PMID 8641455 DOI: 10.1016/0014-5793(96)00362-6  0.547
1996 Nagahama M, Orci L, Ravazzola M, Amherdt M, Lacomis L, Tempst P, Rothman JE, Söllner TH. A v-SNARE implicated in intra-Golgi transport. The Journal of Cell Biology. 133: 507-16. PMID 8636227 DOI: 10.1083/jcb.133.3.507  0.528
1996 Rothman JE, Orci L. Budding vesicles in living cells. Scientific American. 274: 70-5. PMID 8607018 DOI: 10.1038/Scientificamerican0396-70  0.468
1996 Rothman JE, Wieland FT. Protein sorting by transport vesicles. Science (New York, N.Y.). 272: 227-34. PMID 8602507 DOI: 10.1126/Science.272.5259.227  0.545
1995 DeBello WM, O'Connor V, Dresbach T, Whiteheart SW, Wang SS, Schweizer FE, Betz H, Rothman JE, Augustine GJ. SNAP-mediated protein-protein interactions essential for neurotransmitter release. Nature. 373: 626-30. PMID 7854421 DOI: 10.1038/373626A0  0.717
1995 Miesenböck G, Rothman JE. The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack. The Journal of Cell Biology. 129: 309-19. PMID 7721936 DOI: 10.1083/Jcb.129.2.309  0.713
1995 Stamnes MA, Craighead MW, Hoe MH, Lampen N, Geromanos S, Tempst P, Rothman JE. An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding. Proceedings of the National Academy of Sciences of the United States of America. 92: 8011-5. PMID 7644530 DOI: 10.1073/pnas.92.17.8011  0.547
1995 Schiavo G, Gmachl MJ, Stenbeck G, Söllner TH, Rothman JE. A possible docking and fusion particle for synaptic transmission. Nature. 378: 733-6. PMID 7501022 DOI: 10.1038/378733A0  0.64
1994 Elazar Z, Mayer T, Rothman JE. Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks Journal of Biological Chemistry. 269: 794-797. PMID 8288626  0.486
1994 Kuge O, Dascher C, Orci L, Rowe T, Amherdt M, Plutner H, Ravazzola M, Tanigawa G, Rothman JE, Balch WE. Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments. The Journal of Cell Biology. 125: 51-65. PMID 8138575 DOI: 10.1083/Jcb.125.1.51  0.748
1994 Hara-Kuge S, Kuge O, Orci L, Amherdt M, Ravazzola M, Wieland FT, Rothman JE. En Bloc incorporation of coatomer subunits during the assembly of COP-coated vesicles Journal of Cell Biology. 124: 883-892. PMID 8132710 DOI: 10.1083/Jcb.124.6.883  0.429
1994 Elazar Z, Orci L, Ostermann J, Amherdt M, Tanigawa G, Rothman JE. ADP-ribosylation factor and coatomer couple fusion to vesicle budding Journal of Cell Biology. 124: 415-424. PMID 8106543 DOI: 10.1083/Jcb.124.4.415  0.577
1994 Whiteheart SW, Rossnagel K, Buhrow SA, Brunner M, Jaenicke R, Rothman JE. N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion. The Journal of Cell Biology. 126: 945-54. PMID 8051214 DOI: 10.1083/Jcb.126.4.945  0.756
1994 Orci L, Perrelet A, Ravazzola M, Amherdt M, Rothman JE, Schekman R. Coatomer-rich endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 91: 11924-8. PMID 7991558 DOI: 10.1073/Pnas.91.25.11924  0.601
1994 Rothman JE. Mechanisms of intracellular protein transport. Nature. 372: 55-63. PMID 7969419 DOI: 10.1038/372055a0  0.616
1994 Søgaard M, Tani K, Ye RR, Geromanos S, Tempst P, Kirchhausen T, Rothman JE, Söllner T. A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell. 78: 937-48. PMID 7923363 DOI: 10.1016/0092-8674(94)90270-4  0.559
1994 Rothman JE, Warren G. Implications of the SNARE hypothesis for intracellular membrane topology and dynamics Current Biology. 4: 220-233. PMID 7922327 DOI: 10.1016/S0960-9822(00)00051-8  0.568
1994 Rothman JE. Intracellular membrane fusion Advances in Second Messenger and Phosphoprotein Research. 29: 81-96. PMID 7848733 DOI: 10.1016/0968-0004(91)90138-L  0.576
1994 Söllner T, Rothman JE. Neurotransmission: harnessing fusion machinery at the synapse Trends in Neurosciences. 17: 344-348. PMID 7526506 DOI: 10.1016/0166-2236(94)90178-3  0.558
1993 Palmer DJ, Helms JB, Beckers CJM, Orci L, Rothman JE. Binding of coatomer to Golgi membranes requires ADP-ribosylation factor Journal of Biological Chemistry. 268: 12083-12089. PMID 8505331  0.441
1993 Stamnes MA, Rothman JE. The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein. Cell. 73: 999-1005. PMID 8500185 DOI: 10.1016/0092-8674(93)90277-W  0.539
1993 Helms JB, Palmer DJ, Rothman JE. Two distinct populations of ARF bound to Golgi membranes Journal of Cell Biology. 121: 751-760. PMID 8491770 DOI: 10.1083/Jcb.121.4.751  0.57
1993 Orci L, Palmer DJ, Ravazzola M, Perrelet A, Amherdt M, Rothman JE. Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins Nature. 362: 651-652. PMID 8464517 DOI: 10.1038/362648A0  0.549
1993 Whiteheart SW, Griff IC, Brunner M, Clary DO, Mayer T, Buhrow SA, Rothman JE. SNAP family of NSF attachment proteins includes a brain-specific isoform. Nature. 362: 353-5. PMID 8455721 DOI: 10.1038/362353A0  0.765
1993 Söllner T, Whiteheart SW, Brunner M, Erdjument-Bromage H, Geromanos S, Tempst P, Rothman JE. SNAP receptors implicated in vesicle targeting and fusion Nature. 362: 318-324. PMID 8455717 DOI: 10.1038/362318A0  0.797
1993 Tagaya M, Wilson DW, Brunner M, Arango N, Rothman JE. Domain structure of an N-ethylmaleimide-sensitive fusion protein involved in vesicular transport Journal of Biological Chemistry. 268: 2662-2666. PMID 8428942  0.413
1993 Orci L, Palmer DJ, Amherdt M, Rothman JE. Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol Nature. 364: 732-734. PMID 8355790 DOI: 10.1038/364732A0  0.524
1993 Kuge O, Hara-Kuge S, Orci L, Ravazzola M, Amherdt M, Tanigawa G, Wieland FT, Rothman JE. ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly Journal of Cell Biology. 123: 1727-1734. PMID 8276893 DOI: 10.1083/Jcb.123.6.1727  0.471
1993 Tanigawa G, Orci L, Amherdt M, Ravazzola M, Helms JB, Rothman JE. Hydrolysis of bound GTP by ARF protein triggers uncoating of golgi-derived COP-coated vesicles Journal of Cell Biology. 123: 1365-1371. PMID 8253837 DOI: 10.1083/Jcb.123.6.1365  0.548
1993 Ostermann J, Orci L, Tani K, Amherdt M, Ravazzola M, Elazar Z, Rothman JE. Stepwise assembly of functionally active transport vesicles Cell. 75: 1015-1025. PMID 8252615 DOI: 10.1016/0092-8674(93)90545-2  0.556
1993 Orci L, Perrelet A, Ravazzola M, Wieland FT, Schekman R, Rothman JE. "BFA bodies": A subcompartment of the endoplasmic reticulum Proceedings of the National Academy of Sciences of the United States of America. 90: 11089-11093. PMID 8248213 DOI: 10.1073/Pnas.90.23.11089  0.598
1993 Söllner T, Bennett MK, Whiteheart SW, Scheller RH, Rothman JE. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell. 75: 409-18. PMID 8221884 DOI: 10.1016/0092-8674(93)90376-2  0.741
1993 Park K, Flynn GC, Rothman JE, Fasman GD. Conformational change of chaperone Hsc70 upon binding to a decapeptide: A circular dichroism study Protein Science. 2: 325-330. PMID 8095833 DOI: 10.1002/Pro.5560020304  0.562
1993 Tagaya M, Wilson D, Brunner M, Arango N, Rothman J. Domain structure of an N-ethylmaleimide-sensitive fusion protein involved in vesicular transport. Journal of Biological Chemistry. 268: 2662-2666. DOI: 10.1016/s0021-9258(18)53825-4  0.626
1992 Rothman JE, Orci L. Molecular dissection of the secretory pathway Nature. 355: 409-415. PMID 1734280 DOI: 10.1038/355409A0  0.457
1992 Kahn RA, Randazzo P, Serafini T, Weiss O, Rulka C, Clark J, Amherdt M, Roller P, Orci L, Rothman JE. The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. The Journal of Biological Chemistry. 267: 13039-46. PMID 1618801  0.408
1992 Whiteheart SW, Brunner M, Wilson DW, Wiedmann M, Rothman JE. Soluble N-ethylmaleimide-sensitive fusion attachment proteins (SNAPs) bind to a multi-SNAP receptor complex in Golgi membranes Journal of Biological Chemistry. 267: 12239-12243. PMID 1601890  0.681
1992 Griff IC, Schekman R, Rothman JE, Kaiser CA. The yeast SEC17 gene product is functionally equivalent to mammalian α-SNAP protein Journal of Biological Chemistry. 267: 12106-12115. PMID 1601878  0.504
1992 Waters MG, Clary DO, Rothman JE. A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack. The Journal of Cell Biology. 118: 1015-26. PMID 1512287 DOI: 10.1083/Jcb.118.5.1015  0.736
1992 Waters MG, Beckers CJ, Rothman JE. Purification of coat protomers. Methods in Enzymology. 219: 331-7. PMID 1488006 DOI: 10.1016/0076-6879(92)19033-3  0.788
1992 Clary DO, Rothman JE. Purification of soluble N-ethylmaleimide-sensitive fusion attachment proteins from bovine brain microsomes. Methods in Enzymology. 219: 319-30. PMID 1488004 DOI: 10.1016/0076-6879(92)19032-2  0.562
1992 Wilson DW, Rothman JE. [29] Expression and purification of recombinant N-ethylmaleimide-sensitive fusion protein from Escherichia coli Methods in Enzymology. 219: 309-318. PMID 1488003 DOI: 10.1016/0076-6879(92)19031-Z  0.329
1992 Block MR, Rothman JE. [28] Purification of N-ethylmaleimide-sensitive fusion protein Methods in Enzymology. 219: 300-309. PMID 1488002 DOI: 10.1016/0076-6879(92)19030-A  0.51
1992 Serafini T, Rothman JE. Purification of Golgi cisternae-derived non-clathrin-coated vesicles. Methods in Enzymology. 219: 286-99. PMID 1488001 DOI: 10.1016/0076-6879(92)19029-6  0.545
1992 Helms JB, Rothman JE. Inhibition by brefeldin a of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF Nature. 360: 352-354. PMID 1448152 DOI: 10.1038/360352A0  0.564
1992 Stenbeck G, Schreiner R, Herrmann D, Auerbach S, Lottspeich F, Rothman JE, Wieland FT. γ-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p Febs Letters. 314: 195-198. PMID 1360908 DOI: 10.1016/0014-5793(92)80973-K  0.465
1992 Bochkareva ES, Lissin NM, Flynn GC, Rothman JE, Girshovich AS. Positive cooperativity in the functioning of molecular chaperone GroEL Journal of Biological Chemistry. 267: 6796-6800. PMID 1348056  0.301
1992 Beckers CJM, Rothman JE. [2] Transport between Golgi cisternae Methods in Enzymology. 219: 5-12. PMID 1336807 DOI: 10.1016/0076-6879(92)19004-P  0.514
1992 Wilson DW, Whiteheart SW, Wiedmann M, Brunner M, Rothman JE. A multisubunit particle implicated in membrane fusion Journal of Cell Biology. 117: 531-538. PMID 1315316 DOI: 10.1083/Jcb.117.3.531  0.772
1992 Whiteheart S, Brunner M, Wilson D, Wiedmann M, Rothman J. Soluble N-ethylmaleimide-sensitive fusion attachment proteins (SNAPs) bind to a multi-SNAP receptor complex in Golgi membranes. Journal of Biological Chemistry. 267: 12239-12243. DOI: 10.1016/s0021-9258(19)49830-x  0.664
1991 Orci L, Tagaya M, Amherdt M, Perrelet A, Donaldson JG, Lippincott-Schwartz J, Klausner RD, Rothman JE. Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae. Cell. 64: 1183-95. PMID 2004424 DOI: 10.1016/0092-8674(91)90273-2  0.505
1991 Wilson DW, Whiteheart SW, Orci L, Rothman JE. Intracellular membrane fusion. Trends in Biochemical Sciences. 16: 334-7. PMID 1949154 DOI: 10.1016/0968-0004(91)90138-L  0.723
1991 Waters MG, Serafini T, Rothman JE. 'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles. Nature. 349: 248-51. PMID 1898986 DOI: 10.1038/349248a0  0.699
1991 Serafini T, Stenbeck G, Brecht A, Lottspeich F, Orci L, Rothman JE, Wieland FT. A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin. Nature. 349: 215-20. PMID 1898984 DOI: 10.1038/349215a0  0.36
1991 Rothman JE. Enzymology of intracellular membrane fusion Klinische Wochenschrift. 69: 98-104. PMID 1849579 DOI: 10.1007/BF01795952  0.498
1991 Flynn GC, Pohl J, Flocco MT, Rothman JE. Peptide-binding specificity of the molecular chaperone BiP Nature. 353: 726-730. PMID 1834945 DOI: 10.1038/353726A0  0.371
1991 Waters MG, Griff IC, Rothman JE. Proteins involved in vesicular transport and membrane fusion. Current Opinion in Cell Biology. 3: 615-20. PMID 1772655 DOI: 10.1016/0955-0674(91)90031-S  0.743
1991 Serafini T, Orci L, Amherdt M, Brunner M, Kahn RA, Rothman JE. ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell. 67: 239-53. PMID 1680566 DOI: 10.1016/0092-8674(91)90176-Y  0.659
1990 Rothman JE, Orci L. Movement of proteins through the Golgi stack: A molecular dissection of vesicular transport Faseb Journal. 4: 1460-1468. PMID 2407590 DOI: 10.1096/Fasebj.4.5.2407590  0.492
1990 Pfanner N, Glick BS, Arden SR, Rothman JE. Fatty acylation promotes fusion of transport vesicles with Golgi cisternae. The Journal of Cell Biology. 110: 955-61. PMID 2324202 DOI: 10.1083/Jcb.110.4.955  0.707
1990 Helms JB, Karrenbauer A, Wirtz KW, Rothman JE, Wieland FT. Reconstitution of steps in the constitutive secretory pathway in permeabilized cells. Secretion of glycosylated tripeptide and truncated sphingomyelin. The Journal of Biological Chemistry. 265: 20027-32. PMID 2246279  0.418
1990 Rothman JE. Phospholipid transfer market Nature. 347: 519-520. PMID 2215677 DOI: 10.1038/347519A0  0.317
1990 Karrenbauer A, Jeckel D, Just W, Birk R, Schmidt RR, Rothman JE, Wieland FT. The rate of bulk flow from the Golgi to the plasma membrane Cell. 63: 259-267. PMID 2208286 DOI: 10.1016/0092-8674(90)90159-C  0.469
1990 Clary DO, Rothman JE. Purification of three related peripheral membrane proteins needed for vesicular transport. The Journal of Biological Chemistry. 265: 10109-17. PMID 2190980  0.486
1990 Rothman JE. The reconstitution of intracellular protein transport in cell-free systems Harvey Lectures. 86: 65-85. PMID 2152140  0.446
1990 Clary DO, Griff IC, Rothman JE. SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast. Cell. 61: 709-21. PMID 2111733 DOI: 10.1016/0092-8674(90)90482-T  0.582
1990 WILSON D, ROTHMAN J. Heterologous expression of active epitope-tagged NSF Cell Biology International Reports. 14: 236. DOI: 10.1016/0309-1651(90)91043-4  0.317
1990 WILSON D, ROTHMAN J. Function & localisation of NSF during vesicular transport Cell Biology International Reports. 14: 52. DOI: 10.1016/0309-1651(90)90313-N  0.427
1990 Rothman JE. A molecular dissection of vesicular transport Cell Biology International Reports. 14: 2. DOI: 10.1016/0309-1651(90)90123-G  0.423
1989 Pfanner N, Orci L, Glick BS, Amherdt M, Arden SR, Malhotra V, Rothman JE. Fatty acyl-coenzyme A is required for budding of transport vesicles from Golgi cisternae. Cell. 59: 95-102. PMID 2790961 DOI: 10.1016/0092-8674(89)90872-6  0.711
1989 Flynn GC, Chappell TG, Rothman JE. Peptide binding and release by proteins implicated as catalysts of protein assembly Science. 245: 385-390. PMID 2756425 DOI: 10.1126/Science.2756425  0.405
1989 Malhotra V, Serafini T, Orci L, Shepherd JC, Rothman JE. Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack. Cell. 58: 329-36. PMID 2752426 DOI: 10.1016/0092-8674(89)90847-7  0.682
1989 Diaz R, Mayorga LS, Weidman PJ, Rothman JE, Stahl PD. Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport. Nature. 339: 398-400. PMID 2725659 DOI: 10.1038/339398A0  0.828
1989 Wilson DW, Wilcox CA, Flynn GC, Chen E, Kuang WJ, Henzel WJ, Block MR, Ullrich A, Rothman JE. A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast Nature. 339: 355-359. PMID 2657434 DOI: 10.1038/339355a0  0.557
1989 Rothman JE. Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells Cell. 59: 591-601. PMID 2573430 DOI: 10.1016/0092-8674(89)90005-6  0.503
1989 Beckers CJ, Block MR, Glick BS, Rothman JE, Balch WE. Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein. Nature. 339: 397-8. PMID 2542798 DOI: 10.1038/339397A0  0.825
1989 Weidman PJ, Melançon P, Block MR, Rothman JE. Binding of an N-ethylmaleimide-sensitive fusion protein to Golgi membranes requires both a soluble protein(s) and an integral membrane receptor. The Journal of Cell Biology. 108: 1589-96. PMID 2541136 DOI: 10.1083/Jcb.108.5.1589  0.834
1989 Orci L, Malhotra V, Amherdt M, Serafini T, Rothman JE. Dissection of a single round of vesicular transport: sequential intermediates for intercisternal movement in the Golgi stack. Cell. 56: 357-68. PMID 2536591 DOI: 10.1016/0092-8674(89)90239-0  0.656
1989 Melançon P, Glick BS, Malhotra V, Weidman PJ, Serafini T, Orci L, Rothman JE. A role for GTP-binding proteins in vesicular transport through the Golgi complex. Society of General Physiologists Series. 44: 175-88. PMID 2506649  0.815
1989 Rothman JE. GTP and methionine bristles Nature. 340: 433-434. PMID 2502716 DOI: 10.1038/340433A0  0.374
1988 Rothman JE. Reconstruction of organelle function in cell-free systems: introduction Progress in Clinical and Biological Research. 270: 311-316. PMID 3413176  0.226
1988 Malhotra V, Orci L, Glick BS, Block MR, Rothman JE. Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack. Cell. 54: 221-7. PMID 3390865 DOI: 10.1016/0092-8674(88)90554-5  0.759
1988 Block MR, Glick BS, Wilcox CA, Wieland FT, Rothman JE. Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport. Proceedings of the National Academy of Sciences of the United States of America. 85: 7852-6. PMID 3186695 DOI: 10.1073/Pnas.85.21.7852  0.681
1987 Glick BS, Rothman JE. Possible role for fatty acyl-coenzyme A in intracellular protein transport. Nature. 326: 309-12. PMID 3821906 DOI: 10.1038/326309a0  0.667
1987 Rothman JE. Protein sorting by selective retention in the endoplasmic reticulum and Golgi stack Cell. 50: 521-522. PMID 3607878 DOI: 10.1016/0092-8674(87)90024-9  0.456
1987 Wieland FT, Gleason ML, Serafini TA, Rothman JE. The rate of bulk flow from the endoplasmic reticulum to the cell surface. Cell. 50: 289-300. PMID 3594573 DOI: 10.1016/0092-8674(87)90224-8  0.47
1987 Pfeffer SR, Rothman JE. Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Annual Review of Biochemistry. 56: 829-52. PMID 3304148 DOI: 10.1146/Annurev.Bi.56.070187.004145  0.674
1987 Rothman JE. Transport of the vesicular stomatitis glycoprotein to trans Golgi membranes in a cell-free system Journal of Biological Chemistry. 262: 12502-12510. PMID 3040752  0.452
1987 Chappell TG, Konforti BB, Schmid SL, Rothman JE. The ATPase core of a clathrin uncoating protein. The Journal of Biological Chemistry. 262: 746-51. PMID 3027066  0.524
1987 Melançon P, Glick BS, Malhotra V, Weidman PJ, Serafini T, Gleason ML, Orci L, Rothman JE. Involvement of GTP-binding "G" proteins in transport through the Golgi stack. Cell. 51: 1053-62. PMID 2826014 DOI: 10.1016/0092-8674(87)90591-5  0.834
1986 Rothman JE, Kornberg RD. Cell biology. An unfolding story of protein translocation. Nature. 322: 209-10. PMID 3526158 DOI: 10.1038/322209A0  0.459
1986 Dunphy WG, Pfeffer SR, Clary DO, Wattenberg BW, Glick BS, Rothman JE. Yeast and mammals utilize similar cytosolic components to drive protein transport through the Golgi complex. Proceedings of the National Academy of Sciences of the United States of America. 83: 1622-6. PMID 3513182 DOI: 10.1073/Pnas.83.6.1622  0.823
1986 Rothman JE. Cell biology: Life without clathrin Nature. 319: 96-97. PMID 3079886 DOI: 10.1038/319096B0  0.341
1986 Pâquet MR, Pfeffer SR, Burczak JD, Glick BS, Rothman JE. Components responsible for transport between successive Golgi cisternae are highly conserved in evolution. The Journal of Biological Chemistry. 261: 4367-70. PMID 3007452  0.707
1986 Wattenberg BW, Rothman JE. Multiple cytosolic components promote intra-Golgi protein transport. Resolution of a protein acting at a late stage, prior to membrane fusion. The Journal of Biological Chemistry. 261: 2208-13. PMID 3003102  0.434
1986 Wattenberg BW, Balch WE, Rothman JE. A novel prefusion complex formed during protein transport between Golgi cisternae in a cell-free system. The Journal of Biological Chemistry. 261: 2202-7. PMID 3003101  0.718
1986 Chappell TG, Welch WJ, Schlossman DM, Palter KB, Schlesinger MJ, Rothman JE. Uncoating ATPase is a member of the 70 kilodalton family of stress proteins. Cell. 45: 3-13. PMID 2937542 DOI: 10.1016/0092-8674(86)90532-5  0.419
1986 Orci L, Glick BS, Rothman JE. A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell. 46: 171-84. PMID 2872969 DOI: 10.1016/0092-8674(86)90734-8  0.692
1986 Rothman JE, Schmid SL. Enzymatic recycling of clathrin from coated vesicles. Cell. 46: 5-9. PMID 2872968 DOI: 10.1016/0092-8674(86)90852-4  0.581
1985 Brands R, Snider MD, Hino Y, Park SS, Gelboin HV, Rothman JE. Retention of membrane proteins by the endoplasmic reticulum. The Journal of Cell Biology. 101: 1724-32. PMID 3932365 DOI: 10.1083/JCB.101.5.1724  0.511
1985 Rothman JE. The compartmental organization of the Golgi apparatus. Scientific American. 253: 74-89. PMID 3929377 DOI: 10.1038/Scientificamerican0985-74  0.335
1985 Dunphy WG, Rothman JE. Compartmental organization of the golgi stack Cell. 42: 13-21. PMID 3926324 DOI: 10.1016/S0092-8674(85)80097-0  0.627
1985 Hino Y, Rothman JE. Glucosidase II, a glycoprotein of the endoplasmic reticulum membrane. Proteolytic cleavage into enzymatically active fragments. Biochemistry. 24: 800-805. PMID 3888264 DOI: 10.1021/Bi00324A040  0.404
1985 Dunphy WG, Brands R, Rothman JE. Attachment of terminal N-acetylglucosamine to asparagine-linked oligosaccharides occurs in central cisternae of the golgi stack Cell. 40: 463-472. PMID 3155653 DOI: 10.1016/0092-8674(85)90161-8  0.674
1985 Balch WE, Rothman JE. Characterization of protein transport between successive compartments of the Golgi apparatus: asymmetric properties of donor and acceptor activities in a cell-free system. Archives of Biochemistry and Biophysics. 240: 413-25. PMID 2990347 DOI: 10.1016/0003-9861(85)90046-3  0.753
1985 Schmid SL, Braell WA, Rothman JE. ATP catalyzes the sequestration of clathrin during enzymatic uncoating. The Journal of Biological Chemistry. 260: 10057-62. PMID 2862148  0.515
1985 Schmid SL, Rothman JE. Two classes of binding sites for uncoating protein in clathrin triskelions. The Journal of Biological Chemistry. 260: 10050-6. PMID 2862147  0.562
1985 Schmid SL, Rothman JE. Enzymatic dissociation of clathrin cages in a two-stage process. The Journal of Biological Chemistry. 260: 10044-9. PMID 2862146  0.568
1984 Rothman JE, Miller RL, Urbani LJ. Intercompartmental transport in the Golgi complex is a dissociative process: facile transfer of membrane protein between two Golgi populations. The Journal of Cell Biology. 99: 260-71. PMID 6539782 DOI: 10.1083/jcb.99.1.260  0.531
1984 Balch WE, Dunphy WG, Braell WA, Rothman JE. Reconstitution of the transport of protein between successive compartments of the Golgi measured by the coupled incorporation of N-acetylglucosamine. Cell. 39: 405-16. PMID 6498939 DOI: 10.1016/0092-8674(84)90019-9  0.815
1984 Rothman JE, Urbani LJ, Brands R. Transport of protein between cytoplasmic membranes of fused cells: correspondence to processes reconstituted in a cell-free system. The Journal of Cell Biology. 99: 248-59. PMID 6429157 DOI: 10.1083/jcb.99.1.248  0.512
1984 Schmid SL, Braell WA, Schlossman DM, Rothman JE. A role for clathrin light chains in the recognition of clathrin cages by 'uncoating ATPase'. Nature. 311: 228-31. PMID 6148701 DOI: 10.1038/311228A0  0.619
1984 Braell WA, Schlossman DM, Schmid SL, Rothman JE. Dissociation of clathrin coats coupled to the hydrolysis of ATP: role of an uncoating ATPase. The Journal of Cell Biology. 99: 734-41. PMID 6146631 DOI: 10.1083/Jcb.99.2.734  0.578
1984 Schlossman DM, Schmid SL, Braell WA, Rothman JE. An enzyme that removes clathrin coats: purification of an uncoating ATPase. The Journal of Cell Biology. 99: 723-33. PMID 6146630 DOI: 10.1083/Jcb.99.2.723  0.619
1984 Balch WE, Glick BS, Rothman JE. Sequential intermediates in the pathway of intercompartmental transport in a cell-free system. Cell. 39: 525-36. PMID 6096009 DOI: 10.1016/0092-8674(84)90459-8  0.809
1984 Braell WA, Balch WE, Dobbertin DC, Rothman JE. The glycoprotein that is transported between successive compartments of the Golgi in a cell-free system resides in stacks of cisternae. Cell. 39: 511-24. PMID 6096008 DOI: 10.1016/0092-8674(84)90458-6  0.742
1984 Rothman JE, Lenard J. Membrane traffic in animal cells Trends in Biochemical Sciences. 9: 176-178. DOI: 10.1016/0968-0004(84)90132-4  0.534
1984 Rothman JE. Assembly of cell membranes Fresenius Journal of Analytical Chemistry. 317: 616-616. DOI: 10.1007/Bf00593778  0.6
1983 Balch WE, Fries E, Dunphy WH, Urbani LJ, Rothman JE. Transport-coupled oligosaccharide processing in a cell-free system. Methods in Enzymology. 98: 37-47. PMID 6321905 DOI: 10.1016/0076-6879(83)98137-5  0.71
1983 Rothman JE. The Golgi apparatus: roles for distinct 'cis' and 'trans' compartments. Ciba Foundation Symposium. 120-37. PMID 6295718 DOI: 10.1002/9780470720745.CH7  0.327
1983 Dunphy WG, Rothman JE. Compartmentation of asparagine-linked oligosaccharide processing in the Golgi apparatus Journal of Cell Biology. 97: 270-275. PMID 6223041 DOI: 10.1083/Jcb.97.1.270  0.676
1982 Patzer EJ, Schlossman DM, Rothman JE. Release of clathrin from coated vesicles dependent upon a nucleoside triphosphate and a cytosol fraction. Journal of Cell Biology. 93: 230-236. PMID 7068757 DOI: 10.1083/Jcb.93.1.230  0.456
1982 Rothman JE, Fries E, Dunphy WG, Urbani LJ. The Golgi apparatus, coated vesicles, and the sorting problem Cold Spring Harbor Symposia On Quantitative Biology. 46: 797-805. PMID 6955107 DOI: 10.1101/SQB.1982.046.01.075  0.666
1982 Schmid SL, Matsumoto AK, Rothman JE. A domain of clathrin that forms coats. Proceedings of the National Academy of Sciences of the United States of America. 79: 91-5. PMID 6948304 DOI: 10.1073/Pnas.79.1.91  0.56
1981 Rothman JE. The golgi apparatus: two organelles in tandem. Science. 213: 1212-1219. PMID 7268428 DOI: 10.1126/Science.7268428  0.442
1981 Dunphy WG, Fries E, Urbani LJ, Rothman JE. Early and late functions associated with the Golgi apparatus reside in distinct compartments Proceedings of the National Academy of Sciences of the United States of America. 78: 7453-7457. PMID 6801652 DOI: 10.1073/pnas.78.12.7453  0.734
1981 Fries E, Rothman JE. Transient activity of Golgi-like membranes as donors of vesicular stomatitis viral glycoprotein in vitro. The Journal of Cell Biology. 90: 697-704. PMID 6270159 DOI: 10.1083/JCB.90.3.697  0.466
1981 Rubenstein JL, Fine RE, Luskey BD, Rothman JE. Purification of coated vesicles by agarose gel electrophoresis. The Journal of Cell Biology. 89: 357-61. PMID 6265464 DOI: 10.1083/Jcb.89.2.357  0.592
1981 Rothman JE, Fries E. Transport of newly synthesized vesicular stomatitis viral glycoprotein to purified Golgi membranes. Journal of Cell Biology. 89: 162-168. PMID 6262330 DOI: 10.1083/Jcb.89.1.162  0.554
1980 Fries E, Rothman JE. Transport of vesicular stomatitis virus glycoprotein in a cell-free extract Proceedings of the National Academy of Sciences of the United States of America. 77: 3870-3874. PMID 6253996 DOI: 10.1073/Pnas.77.7.3870  0.549
1980 Rothman JE, Bursztyn-Pettegrew H, Fine RE. Transport of the membrane glycoprotein of vesicular stomatitis virus to the cell surface in two stages by clathrin-coated vesicles Journal of Cell Biology. 86: 162-171. PMID 6252211 DOI: 10.1083/Jcb.86.1.162  0.508
1980 Rothman JE, Fine RE. Coated vesicles transport newly synthesized membrane glycoproteins from endoplasmic reticulum to plasma membrane in two successive stages Proceedings of the National Academy of Sciences of the United States of America. 77: 780-784. PMID 6244586 DOI: 10.1073/Pnas.77.2.780  0.532
1979 Lodish HF, Rothman JE. The assembly of cell membranes. Scientific American. 240: 48-63. PMID 451523 DOI: 10.1038/Scientificamerican0179-48  0.616
1978 Rothman JE, Katz FN, Lodish HF. Glycosylation of a membrane protein is restricted to the growing polypeptide chain but is not necessary for insertion as a transmembrane protein. Cell. 15: 1447-54. PMID 215329 DOI: 10.1016/0092-8674(78)90068-5  0.659
1978 Lodish HF, Katz FN, Rothman JE, Knipe DM. Membrane assembly: synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein. Birth Defects Original Article Series. 14: 155-75. PMID 205281  0.56
1977 Rothman JE, Kennedy EP. Rapid transmembrane movement of newly synthesized phospholipids during membrane assembly. Proceedings of the National Academy of Sciences of the United States of America. 74: 1821-5. PMID 405668 DOI: 10.1073/Pnas.74.5.1821  0.67
1977 Rothman JE, Kennedy EP. Asymmetrical distribution of phospholipids in the membrane of Bacillus megaterium. Journal of Molecular Biology. 110: 603-18. PMID 403290 DOI: 10.1016/S0022-2836(77)80114-9  0.678
1977 Rothman JE, Lenard J. Membrane asymmetry. Science (New York, N.Y.). 195: 743-53. PMID 402030 DOI: 10.1126/science.402030  0.494
1977 Katz FN, Rothman JE, Knipe DM, Lodish HF. Membrane assembly: synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein. Journal of Supramolecular Structure. 7: 353-70. PMID 211348 DOI: 10.1002/Jss.400070308  0.637
1977 Rothman JE, Lodish HF. Synchronised transmembrane insertion and glycosylation of a nascent membrane protein. Nature. 269: 775-80. PMID 200844 DOI: 10.1038/269775A0  0.643
1977 Katz FN, Rothman JE, Lingappa VR, Blobel G, Lodish HF. Membrane assembly in vitro: synthesis, glycosylation, and asymmetric insertion of a transmembrane protein. Proceedings of the National Academy of Sciences of the United States of America. 74: 3278-82. PMID 198778 DOI: 10.1073/Pnas.74.8.3278  0.739
1976 Rothman JE, Tsai DK, Dawidowicz EA, Lenard J. Transbilayer phospholipid asymmetry and its maintenance in the membrane of influenza virus. Biochemistry. 15: 2361-70. PMID 1276143 DOI: 10.1021/Bi00656A018  0.524
1976 Lenard J, Rothman JE. Transbilayer distribution and movement of cholesterol and phospholipid in the membrane of influenza virus. Proceedings of the National Academy of Sciences of the United States of America. 73: 391-395. PMID 1061141 DOI: 10.1073/Pnas.73.2.391  0.456
1976 Dawidowicz EA, Rothman JE. Fusion and protein-mediated phospholipid exchange studied with single bilayer phosphatidylcholine vesicles of different density. Biochimica Et Biophysica Acta. 455: 621-30. PMID 999931 DOI: 10.1016/0005-2736(76)90036-5  0.52
1975 Rothman JE, Dawidowicz EA. Asymmetric exchange of vesicle phospholipids catalyzed by the phosphatidylcholine exhange protein. Measurement of inside--outside transitions. Biochemistry. 14: 2809-16. PMID 1148179 DOI: 10.1021/Bi00684A004  0.566
1973 Rothman JE. The molecular basis of mesomorphic phase transitions in phospholipid systems Journal of Theoretical Biology. 38: 1-16. PMID 4707778 DOI: 10.1016/0022-5193(73)90221-X  0.382
1972 Engelman DM, Rothman JE. The planar organization of lecithin-cholesterol bilayers Journal of Biological Chemistry. 247: 3694-3697. PMID 5030638  0.236
1972 Rothman JE, Engelman DM. Molecular mechanism for the interaction of phospholipid with cholesterol Nature: New Biology. 237: 42-44. PMID 4503742 DOI: 10.1038/Newbio237042A0  0.374
1972 Rothman JE, Melchior DL, Morowitz HJ. A Dilatometer for Volume‐Temperature Determinations of Liquids Review of Scientific Instruments. 43: 743-745. DOI: 10.1063/1.1685746  0.574
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