| Year |
Citation |
Score |
| 2020 |
Hart AC, Abell L, Guo J, Mertzman ME, Padmanabha R, Macor JE, Chaudhry C, Lu H, O'Malley K, Shaw PJ, Weigelt C, Pokross M, Kish K, Kim KS, Cornelius L, et al. Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage. Acs Medicinal Chemistry Letters. 11: 266-271. PMID 32184955 DOI: 10.2210/Pdb6Oko/Pdb |
0.333 |
|
| 2018 |
Johnson JA, Tora G, Pi Z, Phillips M, Yin X, Yang R, Zhao L, Chen AY, Taylor DS, Basso M, Rose A, Behnia K, Onorato J, Chen XQ, Abell LM, ... Lu H, et al. Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase. Acs Medicinal Chemistry Letters. 9: 1263-1268. PMID 30613337 DOI: 10.1021/Acsmedchemlett.8B00424 |
0.314 |
|
| 2018 |
Lu H, Iuliano JN, Tonge PJ. Structure-kinetic relationships that control the residence time of drug-target complexes: insights from molecular structure and dynamics. Current Opinion in Chemical Biology. 44: 101-109. PMID 29986213 DOI: 10.1016/J.Cbpa.2018.06.002 |
0.487 |
|
| 2016 |
Lu H, Feng Y, Wang J, Wu Y, Shao H, Yang L. Responses of periphyton morphology, structure, and function to extreme nutrient loading. Environmental Pollution (Barking, Essex : 1987). 214: 878-884. PMID 27173591 DOI: 10.1016/j.envpol.2016.03.069 |
0.432 |
|
| 2016 |
Lai JL, Tao ZY, Fu Q, Han N, Wu G, Zhang H, Lu H, Luo XG. The chemical toxicity of cesium in Indian mustard (Brassica juncea L.) seedlings. Journal of Environmental Radioactivity. 160: 93-101. PMID 27156168 DOI: 10.1016/j.jenvrad.2016.04.023 |
0.473 |
|
| 2016 |
Yu R, Wu J, Liu M, Zhu G, Chen L, Chang Y, Lu H. Toxicity of binary mixtures of metal oxide nanoparticles to Nitrosomonas europaea. Chemosphere. 153: 187-197. PMID 27016814 DOI: 10.1016/J.Chemosphere.2016.03.065 |
0.428 |
|
| 2016 |
Lu H, Kopcho L, Ghosh K, Witmer M, Parker M, Gupta S, Paul M, Krishnamurthy P, Laksmaiah B, Xie D, Tredup J, Zhang L, Abell LM. Development of a rapidfire mass spectrometry assay and a fluorescence assay for kynurenine aminotransferase II. Analytical Biochemistry. PMID 26874021 DOI: 10.1016/J.Ab.2016.02.003 |
0.307 |
|
| 2015 |
Hu J, Shang D, Xu X, He X, Ni X, Zhang M, Wang Z, Qiu C, Deng S, Lu H, Zhu X, Huang W, Wen Y. Effect of grapefruit juice and food on the pharmacokinetics of pirfenidone in healthy Chinese volunteers: a diet-drug interaction study. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-6. PMID 26407124 DOI: 10.3109/00498254.2015.1089365 |
0.31 |
|
| 2012 |
Schiebel J, Chang A, Lu H, Baxter MV, Tonge PJ, Kisker C. Staphylococcus aureus FabI: inhibition, substrate recognition, and potential implications for in vivo essentiality. Structure (London, England : 1993). 20: 802-13. PMID 22579249 DOI: 10.1016/J.Str.2012.03.013 |
0.556 |
|
| 2012 |
Hirschbeck MW, Kuper J, Lu H, Liu N, Neckles C, Shah S, Wagner S, Sotriffer CA, Tonge PJ, Kisker C. Structure of the Yersinia pestis FabV enoyl-ACP reductase and its interaction with two 2-pyridone inhibitors. Structure (London, England : 1993). 20: 89-100. PMID 22244758 DOI: 10.1016/J.Str.2011.07.019 |
0.685 |
|
| 2010 |
Lu H, Tonge PJ. Drug-target residence time: critical information for lead optimization. Current Opinion in Chemical Biology. 14: 467-74. PMID 20663707 DOI: 10.1016/J.Cbpa.2010.06.176 |
0.525 |
|
| 2010 |
Lu H, Tonge PJ. Mechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia mallei. Biochemistry. 49: 1281-9. PMID 20055482 DOI: 10.1021/Bi902001A |
0.549 |
|
| 2009 |
England K, am Ende C, Lu H, Sullivan TJ, Marlenee NL, Bowen RA, Knudson SE, Knudson DL, Tonge PJ, Slayden RA. Substituted diphenyl ethers as a broad-spectrum platform for the development of chemotherapeutics for the treatment of tularaemia. The Journal of Antimicrobial Chemotherapy. 64: 1052-61. PMID 19734171 DOI: 10.1093/Jac/Dkp307 |
0.646 |
|
| 2009 |
Lu H, England K, am Ende C, Truglio JJ, Luckner S, Reddy BG, Marlenee NL, Knudson SE, Knudson DL, Bowen RA, Kisker C, Slayden RA, Tonge PJ. Slow-onset inhibition of the FabI enoyl reductase from francisella tularensis: residence time and in vivo activity. Acs Chemical Biology. 4: 221-31. PMID 19206187 DOI: 10.1021/Cb800306Y |
0.57 |
|
| 2008 |
Lu H, Tonge PJ. Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway. Accounts of Chemical Research. 41: 11-20. PMID 18193820 DOI: 10.1021/Ar700156E |
0.583 |
|
| 2007 |
Boyne ME, Sullivan TJ, amEnde CW, Lu H, Gruppo V, Heaslip D, Amin AG, Chatterjee D, Lenaerts A, Tonge PJ, Slayden RA. Targeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: evaluation of A-ring-modified diphenyl ethers as high-affinity InhA inhibitors. Antimicrobial Agents and Chemotherapy. 51: 3562-7. PMID 17664324 DOI: 10.1128/Aac.00383-07 |
0.653 |
|
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