| Year |
Citation |
Score |
| 2023 |
Sarno J, Domizi P, Liu Y, Merchant M, Pedersen CB, Jedoui D, Jager A, Nolan GP, Gaipa G, Bendall SC, Bava FA, Davis KL. Dasatinib overcomes glucocorticoid resistance in B-cell acute lymphoblastic leukemia. Nature Communications. 14: 2935. PMID 37217509 DOI: 10.1038/s41467-023-38456-y |
0.346 |
|
| 2023 |
Igarashi KJ, Kucinski I, Chan YY, Tan TK, Khoo HM, Kealy D, Bhadury J, Hsu I, Ho PY, Niizuma K, Hickey JW, Nolan G, Bridge KS, Czechowicz A, Gottgens B, et al. Physioxia improves the selectivity of hematopoietic stem cell expansion cultures. Blood Advances. PMID 36809781 DOI: 10.1182/bloodadvances.2023009668 |
0.452 |
|
| 2021 |
Bai Y, Zhu B, Rovira-Clave X, Chen H, Markovic M, Chan CN, Su TH, McIlwain DR, Estes JD, Keren L, Nolan GP, Jiang S. Adjacent Cell Marker Lateral Spillover Compensation and Reinforcement for Multiplexed Images. Frontiers in Immunology. 12: 652631. PMID 34295327 DOI: 10.3389/fimmu.2021.652631 |
0.304 |
|
| 2020 |
Schürch CM, Bhate SS, Barlow GL, Phillips DJ, Noti L, Zlobec I, Chu P, Black S, Demeter J, McIlwain DR, Samusik N, Goltsev Y, Nolan GP. Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front. Cell. PMID 32763154 DOI: 10.1016/J.Cell.2020.07.005 |
0.343 |
|
| 2020 |
Ji AL, Rubin AJ, Thrane K, Jiang S, Reynolds DL, Meyers RM, Guo MG, George BM, Mollbrink A, Bergenstråhle J, Larsson L, Bai Y, Zhu B, Bhaduri A, Meyers JM, ... ... Nolan GP, et al. Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma. Cell. PMID 32579974 DOI: 10.1016/J.Cell.2020.05.039 |
0.404 |
|
| 2020 |
McElroy AK, Akondy RS, Mcllwain DR, Chen H, Bjornson-Hooper Z, Mukherjee N, Mehta AK, Nolan G, Nichol ST, Spiropoulou CF. Immunologic timeline of Ebola virus disease and recovery in humans. Jci Insight. 5. PMID 32434986 DOI: 10.1172/Jci.Insight.137260 |
0.37 |
|
| 2020 |
Su Y, Ko ME, Cheng H, Zhu R, Xue M, Wang J, Lee JW, Frankiw L, Xu A, Wong S, Robert L, Takata K, Yuan D, Lu Y, Huang S, ... ... Nolan GP, et al. Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line. Nature Communications. 11: 2345. PMID 32393797 DOI: 10.1038/S41467-020-15956-9 |
0.721 |
|
| 2020 |
Chen H, Schürch CM, Noble K, Kim K, Krutzik PO, O'Donnell E, Vander Tuig J, Nolan GP, McIlwain DR. Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes. Bmc Immunology. 21: 15. PMID 32228458 DOI: 10.1186/S12865-020-00345-0 |
0.771 |
|
| 2020 |
Teh CE, Gong JN, Segal D, Tan T, Vandenberg CJ, Fedele PL, Low MSY, Grigoriadis G, Harrison SJ, Strasser A, Roberts AW, Huang DCS, Nolan GP, Gray DHD, Ko ME. Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells. Cell Death and Differentiation. PMID 31988495 DOI: 10.1038/S41418-020-0498-Z |
0.464 |
|
| 2020 |
Ko ME, Williams CM, Fread KI, Goggin SM, Rustagi RS, Fragiadakis GK, Nolan GP, Zunder ER. FLOW-MAP: a graph-based, force-directed layout algorithm for trajectory mapping in single-cell time course datasets. Nature Protocols. PMID 31932774 DOI: 10.1038/S41596-019-0246-3 |
0.413 |
|
| 2020 |
Behbehani GK, Finck R, Samusik N, Sridhar K, Fantl WJ, Greenberg PL, Nolan GP. Profiling myelodysplastic syndromes by mass cytometry demonstrates abnormal progenitor cell phenotype and differentiation. Cytometry. Part B, Clinical Cytometry. PMID 31917512 DOI: 10.1002/Cyto.B.21860 |
0.371 |
|
| 2020 |
Schürch CM, Phillips DJ, Gutierrez BR, Matusiak M, Bhate SS, Barlow GL, Fling SP, Ramchurren N, Pierce RH, Cheever MA, Khodadoust MS, West R, Kim YH, Nolan GP. Abstract 6669: Cellular neighborhoods predict pembrolizumab response in cutaneous T cell lymphoma Immunology. 80: 6669-6669. DOI: 10.1158/1538-7445.Am2020-6669 |
0.408 |
|
| 2020 |
Su Y, Li G, Ko M, Cheng H, Zhu R, Xue M, Robert L, Levine R, Ribas A, Nolan G, Wei W, Plevritis S, Baltimore D, Heath JR. Abstract 6585: Systems biology for investigating drug resistance mechanism of melanoma Cancer Research. 80: 6585-6585. DOI: 10.1158/1538-7445.Am2020-6585 |
0.72 |
|
| 2019 |
Bongen E, Lucian H, Khatri A, Fragiadakis GK, Bjornson ZB, Nolan GP, Utz PJ, Khatri P. Sex Differences in the Blood Transcriptome Identify Robust Changes in Immune Cell Proportions with Aging and Influenza Infection. Cell Reports. 29: 1961-1973.e4. PMID 31722210 DOI: 10.1016/J.Celrep.2019.10.019 |
0.32 |
|
| 2019 |
Ding X, Krutzik PO, Ghaffari AA, Zhaozhi Y, Miranda D, Cheng G, Ho CM, Nolan GP, Sanchez DJ. Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation. Antiviral Research. 104598. PMID 31513822 DOI: 10.1016/J.Antiviral.2019.104598 |
0.701 |
|
| 2019 |
Press MF, Xie B, Davenport S, Zhou Y, Guzman R, Nolan GP, O'Brien N, Palazzolo M, Mak TW, Brugge JS, Slamon DJ. Role for polo-like kinase 4 in mediation of cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31097597 DOI: 10.1073/Pnas.1818820116 |
0.366 |
|
| 2019 |
Hartmann FJ, Simonds EF, Vivanco N, Bruce T, Borges L, Nolan GP, Spitzer MH, Bendall SC. Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis. Methods in Molecular Biology (Clifton, N.J.). 1989: 55-81. PMID 31077099 DOI: 10.1007/978-1-4939-9454-0_5 |
0.66 |
|
| 2019 |
Good Z, Borges L, Vivanco Gonzalez N, Sahaf B, Samusik N, Tibshirani R, Nolan GP, Bendall SC. Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells. Nature Biotechnology. PMID 30742126 DOI: 10.1038/S41587-019-0033-2 |
0.434 |
|
| 2019 |
Duckworth AD, Gherardini PF, Sykorova M, Yasin F, Nolan GP, Slupsky JR, Kalakonda N. Multiplexed profiling of RNA and protein expression signatures in individual cells using flow or mass cytometry. Nature Protocols. PMID 30728478 DOI: 10.1038/S41596-018-0120-8 |
0.389 |
|
| 2019 |
Knapp DJHF, Hammond CA, Wang F, Aghaeepour N, Miller PH, Beer PA, Pellacani D, VanInsberghe M, Hansen C, Bendall SC, Nolan GP, Eaves CJ. A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data. Blood. PMID 30622121 DOI: 10.1182/Blood-2018-10-878025 |
0.462 |
|
| 2019 |
Schuerch CM, Phillips DJ, Bhate SS, Barlow GL, Fling SP, Ramchurren N, Pierce R, Cheever MA, Khodadoust MS, Kim YH, Nolan GP. Dynamics of the Cutaneous T Cell Lymphoma Microenvironment in Patients Treated with Pembrolizumab Revealed By Highly Multiplexed Tissue Imaging Blood. 134: 1521-1521. DOI: 10.1182/Blood-2019-125315 |
0.355 |
|
| 2018 |
Rosental B, Kowarsky M, Seita J, Corey DM, Ishizuka KJ, Palmeri KJ, Chen SY, Sinha R, Okamoto J, Mantalas G, Manni L, Raveh T, Clarke DN, Tsai JM, Newman AM, ... ... Nolan GP, et al. Complex mammalian-like haematopoietic system found in a colonial chordate. Nature. PMID 30518860 DOI: 10.1038/S41586-018-0783-X |
0.403 |
|
| 2018 |
Churko JM, Garg P, Treutlein B, Venkatasubramanian M, Wu H, Lee J, Wessells QN, Chen SY, Chen WY, Chetal K, Mantalas G, Neff N, Jabart E, Sharma A, Nolan GP, et al. Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis. Nature Communications. 9: 4906. PMID 30464173 DOI: 10.1038/S41467-018-07333-4 |
0.36 |
|
| 2018 |
Goltsev Y, Samusik N, Kennedy-Darling J, Bhate S, Hale M, Vazquez G, Black S, Nolan GP. Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging. Cell. PMID 30078711 DOI: 10.1016/J.Cell.2018.07.010 |
0.391 |
|
| 2018 |
Hu Z, Jujjavarapu C, Hughey JJ, Andorf S, Lee HC, Gherardini PF, Spitzer MH, Thomas CG, Campbell J, Dunn P, Wiser J, Kidd BA, Dudley JT, Nolan GP, Bhattacharya S, et al. MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data. Cell Reports. 24: 1377-1388. PMID 30067990 DOI: 10.1016/J.Celrep.2018.07.003 |
0.371 |
|
| 2018 |
Wang X, Allen WE, Wright MA, Sylwestrak EL, Samusik N, Vesuna S, Evans K, Liu C, Ramakrishnan C, Liu J, Nolan GP, Bava FA, Deisseroth K. Three-dimensional intact-tissue sequencing of single-cell transcriptional states. Science (New York, N.Y.). PMID 29930089 DOI: 10.1126/Science.Aat5691 |
0.311 |
|
| 2018 |
Aghaeepour N, Simonds EF, Knapp DJHF, Bruggner R, Sachs K, Culos A, Gherardini PF, Samusik N, Fragiadakis G, Bendall S, Gaudilliere B, Angst MS, Eaves CJ, Weiss WA, Fantl W, ... Nolan G, et al. GateFinder: Projection-based Gating Strategy Optimization for Flow and Mass Cytometry. Bioinformatics (Oxford, England). PMID 29850785 DOI: 10.1093/Bioinformatics/Bty430 |
0.738 |
|
| 2018 |
Sarno J, Savino AM, Buracchi C, Palmi C, Pinto S, Bugarin C, Jager A, Bresolin S, Barber RC, Silvestri D, Israeli S, Dyer MJS, Cazzaniga G, Nolan GP, Biondi A, et al. SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia. Oncotarget. 9: 22872-22885. PMID 29796158 DOI: 10.18632/Oncotarget.25089 |
0.44 |
|
| 2018 |
Anchang B, Davis KL, Fienberg HG, Williamson BD, Bendall SC, Karacosta LG, Tibshirani R, Nolan GP, Plevritis SK. DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29654148 DOI: 10.1073/Pnas.1711365115 |
0.359 |
|
| 2018 |
Ajami B, Samusik N, Wieghofer P, Ho PP, Crotti A, Bjornson Z, Prinz M, Fantl WJ, Nolan GP, Steinman L. Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models. Nature Neuroscience. PMID 29507414 DOI: 10.1038/S41593-018-0100-X |
0.369 |
|
| 2018 |
Good Z, Sarno J, Jager A, Samusik N, Aghaeepour N, Simonds EF, White L, Lacayo NJ, Fantl WJ, Fazio G, Gaipa G, Biondi A, Tibshirani R, Bendall SC, Nolan GP, et al. Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse. Nature Medicine. PMID 29505032 DOI: 10.1016/J.Exphem.2018.06.027 |
0.742 |
|
| 2018 |
Gonzalez VD, Samusik N, Chen TJ, Savig ES, Aghaeepour N, Quigley DA, Huang YW, Giangarrà V, Borowsky AD, Hubbard NE, Chen SY, Han G, Ashworth A, Kipps TJ, Berek JS, ... Nolan GP, et al. Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry. Cell Reports. 22: 1875-1888. PMID 29444438 DOI: 10.1016/J.Celrep.2018.01.053 |
0.425 |
|
| 2018 |
Sarno J, Pedersen CB, Jager A, Burns T, Gaipa G, Nolan GP, Bava AF, Davis KL. Glucocorticoids-Resistant Leukemic B-Cells Undergo a Phenotypic Change That Increases Sensitivity to SRC/ABL Inhibition Blood. 132: 1546-1546. DOI: 10.1182/Blood-2018-99-117443 |
0.43 |
|
| 2018 |
Schuerch C, Barlow GL, Bhate SS, Samusik N, Nolan GP, Goltsev Y. Dynamics of the Bone Marrow Microenvironment during Leukemic Progression Revealed By Codex Hyper-Parameter Tissue Imaging Blood. 132: 935-935. DOI: 10.1182/Blood-2018-99-111708 |
0.461 |
|
| 2018 |
Anchang B, Davis K, Fienberg H, Bendall S, Karacosta L, Nolan G, Plevritis SK. Abstract 2275: Individualized drug combination based on single-cell drug perturbations Cancer Research. 78: 2275-2275. DOI: 10.1158/1538-7445.Am2018-2275 |
0.354 |
|
| 2018 |
Sarno J, Pedersen C, Jager A, Burns T, Gaipa G, Nolan G, Bava A, Davis K. Glucocorticoids Exert a Dual Role in B-Cell Acute Lymphoblastic Leukemia: Apoptosis and Differentiation of Early B-Cell Populations Experimental Hematology. 64: S100. DOI: 10.1016/J.Exphem.2018.06.140 |
0.355 |
|
| 2017 |
Li YH, Li D, Samusik N, Wang X, Guan L, Nolan GP, Wong WH. Scalable multi-sample single-cell data analysis by Partition-Assisted Clustering and Multiple Alignments of Networks. Plos Computational Biology. 13: e1005875. PMID 29281633 DOI: 10.1371/Journal.Pcbi.1005875 |
0.372 |
|
| 2017 |
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell PJ, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Nolan G, et al. Science Forum: The Human Cell Atlas. Elife. 6. PMID 29206104 DOI: 10.7554/Elife.27041 |
0.404 |
|
| 2017 |
Han G, Chen SY, Gonzalez VD, Zunder ER, Fantl WJ, Nolan GP. Atomic mass tag of bismuth-209 for increasing the immunoassay multiplexing capacity of mass cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 91: 1150-1163. PMID 29205767 DOI: 10.1002/Cyto.A.23283 |
0.338 |
|
| 2017 |
Kleppe M, Spitzer MH, Li S, Hill CE, Dong L, Papalexi E, De Groote S, Bowman RL, Keller M, Koppikar P, Rapaport FT, Teruya-Feldstein J, Gandara J, Mason CE, Nolan GP, et al. Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis. Cell Stem Cell. PMID 28965767 DOI: 10.1016/J.Stem.2017.08.011 |
0.381 |
|
| 2017 |
Aghaeepour N, Ganio EA, Mcilwain D, Tsai AS, Tingle M, Van Gassen S, Gaudilliere DK, Baca Q, McNeil L, Okada R, Ghaemi MS, Furman D, Wong RJ, Winn VD, Druzin ML, ... ... Nolan GP, et al. An immune clock of human pregnancy. Science Immunology. 2. PMID 28864494 DOI: 10.1126/Sciimmunol.Aan2946 |
0.305 |
|
| 2017 |
Aghaeepour N, Kin C, Ganio EA, Jensen KP, Gaudilliere DK, Tingle M, Tsai A, Lancero HL, Choisy B, McNeil LS, Okada R, Shelton AA, Nolan GP, Angst MS, Gaudilliere BL. Deep Immune Profiling of an Arginine-Enriched Nutritional Intervention in Patients Undergoing Surgery. Journal of Immunology (Baltimore, Md. : 1950). PMID 28794234 DOI: 10.4049/Jimmunol.1700421 |
0.348 |
|
| 2017 |
Vadstrup K, Galsgaard ED, Jensen H, Lanier LL, Ryan JC, Chen SY, Nolan GP, Vester-Andersen MK, Pedersen JS, Gerwien J, Jensen T, Bendtsen F. NKG2D ligand expression in Crohn's disease and NKG2D-dependent stimulation of CD8(+) T cell migration. Experimental and Molecular Pathology. PMID 28684217 DOI: 10.1016/J.Yexmp.2017.06.010 |
0.335 |
|
| 2017 |
Mukherjee S, Jensen H, Stewart W, Stewart D, Ray WC, Chen SY, Nolan GP, Lanier LL, Das J. In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells. Science Signaling. 10. PMID 28655861 DOI: 10.1126/Scisignal.Aai9062 |
0.403 |
|
| 2017 |
Porpiglia E, Samusik N, Van Ho AT, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM. High-resolution myogenic lineage mapping by single-cell mass cytometry. Nature Cell Biology. PMID 28414312 DOI: 10.1038/Ncb3507 |
0.376 |
|
| 2017 |
O'Gorman WE, Kong DS, Balboni IM, Rudra P, Bolen CR, Ghosh D, Davis MM, Nolan GP, Hsieh EW. Mass cytometry identifies a distinct monocyte cytokine signature shared by clinically heterogeneous pediatric SLE patients. Journal of Autoimmunity. PMID 28389038 DOI: 10.1016/J.Jaut.2017.03.010 |
0.342 |
|
| 2017 |
Savino AM, Sarno J, Trentin L, Vieri M, Fazio G, Bardini M, Bugarin C, Fossati G, Davis K, Gaipa G, Izraeli S, Meyer LH, Nolan GP, Biondi A, Te Kronnie G, et al. The histone deacetylase inhibitor givinostat (ITF2357) exhibits potent anti-tumor activity against CRLF2-rearranged BCP-ALL. Leukemia. PMID 28331226 DOI: 10.1038/Leu.2017.93 |
0.411 |
|
| 2017 |
Jensen H, Chen SY, Folkersen L, Nolan GP, Lanier LL. EBI3 regulates the NK cell response to mouse cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 28143936 DOI: 10.1073/Pnas.1700231114 |
0.358 |
|
| 2017 |
Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG. Systemic Immunity Is Required for Effective Cancer Immunotherapy. Cell. PMID 28111070 DOI: 10.1016/J.Cell.2016.12.022 |
0.331 |
|
| 2017 |
Ertsås HC, Nolan GP, LaBarge MA, Lorens JB. Microsphere cytometry to interrogate microenvironment-dependent cell signaling. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 28102399 DOI: 10.1039/C6Ib00207B |
0.478 |
|
| 2017 |
Burns TJ, Frei AP, Gherardini PF, Bava FA, Batchelder JE, Yoshiyasu Y, Yu JM, Groziak AR, Kimmey SC, Gonzalez VD, Fantl WJ, Nolan GP. High-throughput precision measurement of subcellular localization in single cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 28094900 DOI: 10.1002/Cyto.A.23054 |
0.431 |
|
| 2017 |
Baca Q, Cosma A, Nolan G, Gaudilliere B. The road ahead: Implementing mass cytometry in clinical studies, one cell at a time. Cytometry. Part B, Clinical Cytometry. 92: 10-11. PMID 27874247 DOI: 10.1002/Cyto.B.21497 |
0.33 |
|
| 2017 |
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Nolan G, et al. Author response: The Human Cell Atlas Elife. DOI: 10.7554/Elife.27041.011 |
0.346 |
|
| 2017 |
Simonds E, Cayanan G, Park J, Bendall S, Nolan G, Weiss W. STEM-22. Single-cell mass cytometry of human glioblastoma reveals phenotypic heterogeneity and distinct cell cycle and epigenetic states among glioma stem cells Neuro-Oncology. 19: vi230-vi230. DOI: 10.1093/Neuonc/Nox168.937 |
0.755 |
|
| 2017 |
Simonds E, Aghaeepour N, Cayanan G, Park J, Nolan G, Weiss W. HGG-21. IDENTIFICATION OF SMALL MOLECULE KINASE INHIBITORS WITH SPECIFIC ACTIVITY IN PEDIATRIC GLIOMA Neuro-Oncology. 19: iv27-iv27. DOI: 10.1093/Neuonc/Nox083.110 |
0.744 |
|
| 2017 |
Eaves C, Knapp D, Hammond C, Hui A, van Loenhout M, Pellacani D, Wang F, Miller P, Lorzadeh A, Aghaeepour N, Moksa M, Vaninsberghe M, Rabu G, Beer P, Humphries R, ... ... Nolan G, et al. Molecular and biological analysis of human hematopoietic stem cells at single-cell resolution Experimental Hematology. 53: S24. DOI: 10.1016/J.Exphem.2017.06.010 |
0.39 |
|
| 2016 |
Fisher DA, Malkova O, Engle EK, Miner C, Fulbright MC, Behbehani GK, Collins TB, Bandyopadhyay S, Zhou A, Nolan GP, Oh ST. Mass cytometry analysis reveals hyperactive NF Kappa B signaling in myelofibrosis and secondary acute myeloid leukemia. Leukemia. PMID 28008177 DOI: 10.1038/Leu.2016.377 |
0.469 |
|
| 2016 |
Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, et al. Distinct signaling programs control human hematopoietic stem cell survival and proliferation. Blood. PMID 27827829 DOI: 10.1182/Blood-2016-09-740654 |
0.439 |
|
| 2016 |
Fragiadakis GK, Baca QJ, Gherardini PF, Ganio EA, Gaudilliere DK, Tingle M, Lancero HL, McNeil LS, Spitzer MH, Wong RJ, Shaw GM, Darmstadt GL, Sylvester KG, Winn VD, Carvalho B, ... ... Nolan GP, et al. Mapping the Fetomaternal Peripheral Immune System at Term Pregnancy. Journal of Immunology (Baltimore, Md. : 1950). PMID 27793998 DOI: 10.4049/Jimmunol.1601195 |
0.353 |
|
| 2016 |
Anchang B, Hart TD, Bendall SC, Qiu P, Bjornson Z, Linderman M, Nolan GP, Plevritis SK. Visualization and cellular hierarchy inference of single-cell data using SPADE. Nature Protocols. 11: 1264-1279. PMID 27310265 DOI: 10.1038/Nprot.2016.066 |
0.422 |
|
| 2016 |
Mitton B, Chae HD, Hsu K, Dutta R, Aldana-Masangkay G, Ferrari R, Davis K, Tiu BC, Kaul A, Lacayo N, Dahl G, Xie F, Li BX, Breese MR, Landaw EM, ... Nolan G, et al. Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. Leukemia. PMID 27211267 DOI: 10.1038/Leu.2016.139 |
0.426 |
|
| 2016 |
Samusik N, Good Z, Spitzer MH, Davis KL, Nolan GP. Automated mapping of phenotype space with single-cell data. Nature Methods. PMID 27183440 DOI: 10.1038/Nmeth.3863 |
0.388 |
|
| 2016 |
Spitzer MH, Nolan GP. Mass Cytometry: Single Cells, Many Features. Cell. 165: 780-91. PMID 27153492 DOI: 10.1016/J.Cell.2016.04.019 |
0.38 |
|
| 2016 |
Frei AP, Bava FA, Zunder ER, Hsieh EW, Chen SY, Nolan GP, Gherardini PF. Highly multiplexed simultaneous detection of RNAs and proteins in single cells. Nature Methods. PMID 26808670 DOI: 10.1038/Nmeth.3742 |
0.385 |
|
| 2016 |
Hotson AN, Gopinath S, Nicolau M, Khasanova A, Finck R, Monack D, Nolan GP. Coordinate actions of innate immune responses oppose those of the adaptive immune system during Salmonella infection of mice. Science Signaling. 9: ra4. PMID 26758212 DOI: 10.1126/Scisignal.Aaa9303 |
0.345 |
|
| 2016 |
Kleppe M, Spitzer MH, Li S, Dong L, Papalexi E, Hill C, De Groote S, Keller M, Koppikar P, Rapaport F, Gandara J, Mason CE, Nolan GP, Levine RL. JAK1 As a Convergent Regulator of Hematopoietic Stem Cell Function and Stress Hematopoiesis Blood. 128: 722-722. DOI: 10.1182/Blood.V128.22.722.722 |
0.452 |
|
| 2016 |
Saxena NS, Davis KL, Inlay MA, Junger A, Yang Y, Krampf ML, Dejene B, Nolan GP, Weissman IL, Weinberg KI. High Resolution Mapping of Human Lymphopoiesis Reveals a Common Lymphoid Progenitor (CLP) Population Blood. 128: 1473-1473. DOI: 10.1182/Blood.V128.22.1473.1473 |
0.307 |
|
| 2016 |
Bhate SS, Samusik N, Goltsev Y, Nolan GP. Abstract PR14: Automatic identification of cell niches and immune interactions important for clinical outcomes using multiparameter imaging and deep neural networks Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-Pr14 |
0.418 |
|
| 2016 |
Kennedy-Darling J, Nolan GP, Goltsev Y, Samusik N. Abstract A089: Multiparametric immunofluorescence analysis of the tumor microenvironment using CODEX Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A089 |
0.328 |
|
| 2016 |
Good Z, Sarno J, Jager A, Samusik N, Fantl W, Aghaeepour N, Tibshirani R, Bendall SC, Gaipa G, Biondi A, Nolan GP, Davis KL. Abstract 2693: Relapse in BCP-ALL predicted by activated signaling in pro-B cell subsets Cancer Research. 76: 2693-2693. DOI: 10.1158/1538-7445.Am2016-2693 |
0.46 |
|
| 2015 |
Maney SK, McIlwain DR, Polz R, Pandyra AA, Sundaram B, Wolff D, Ohishi K, Maretzky T, Brooke MA, Evers A, Vasudevan AA, Aghaeepour N, Scheller J, Münk C, Häussinger D, ... ... Nolan GP, et al. Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17. Science Signaling. 8: ra109. PMID 26535007 DOI: 10.1126/Scisignal.Aac5356 |
0.38 |
|
| 2015 |
Aghaeepour N, Chattopadhyay P, Chikina M, Dhaene T, Van Gassen S, Kursa M, Lambrecht BN, Malek M, Qian Y, Qiu P, Saeys Y, Stanton R, Tong D, Vens C, Walkowiak S, ... ... Nolan GP, et al. A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 26447924 DOI: 10.1002/Cyto.A.22732 |
0.396 |
|
| 2015 |
Gaudillière B, Ganio EA, Tingle M, Lancero HL, Fragiadakis GK, Baca QJ, Aghaeepour N, Wong RJ, Quaintance C, El-Sayed YY, Shaw GM, Lewis DB, Stevenson DK, Nolan GP, Angst MS. Implementing Mass Cytometry at the Bedside to Study the Immunological Basis of Human Diseases: Distinctive Immune Features in Patients with a History of Term or Preterm Birth. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 26190063 DOI: 10.1002/Cyto.A.22720 |
0.369 |
|
| 2015 |
Schaffert SA, Loh C, Wang S, Arnold CP, Axtell RC, Newell EW, Nolan G, Ansel KM, Davis MM, Steinman L, Chen CZ. mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 26163591 DOI: 10.4049/Jimmunol.1401587 |
0.335 |
|
| 2015 |
Spitzer MH, Gherardini PF, Fragiadakis GK, Bhattacharya N, Yuan RT, Hotson AN, Finck R, Carmi Y, Zunder ER, Fantl WJ, Bendall SC, Engleman EG, Nolan GP. IMMUNOLOGY. An interactive reference framework for modeling a dynamic immune system. Science (New York, N.Y.). 349: 1259425. PMID 26160952 DOI: 10.1126/Science.1259425 |
0.379 |
|
| 2015 |
Raval A, Behbehani GK, Nguyen le XT, Thomas D, Kusler B, Garbuzov A, Ramunas J, Holbrook C, Park CY, Blau H, Nolan GP, Artandi SE, Mitchell BS. Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice. Plos One. 10: e0131722. PMID 26133370 DOI: 10.1371/Journal.Pone.0131722 |
0.361 |
|
| 2015 |
Levine JH, Simonds EF, Bendall SC, Davis KL, Amir ED, Tadmor MD, Litvin O, Fienberg HG, Jager A, Zunder ER, Finck R, Gedman AL, Radtke I, Downing JR, Pe'er D, ... Nolan GP, et al. Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis. Cell. PMID 26095251 DOI: 10.1016/J.Cell.2015.05.047 |
0.736 |
|
| 2015 |
Behbehani GK, Samusik N, Bjornson ZB, Fantl WJ, Medeiros BC, Nolan GP. Mass Cytometric Functional Profiling of Acute Myeloid Leukemia Defines Cell-Cycle and Immunophenotypic Properties That Correlate with Known Responses to Therapy. Cancer Discovery. 5: 988-1003. PMID 26091827 DOI: 10.1158/2159-8290.Cd-15-0298 |
0.4 |
|
| 2015 |
ElSohly AM, Netirojjanakul C, Aanei IL, Jager A, Bendall S, Farkas ME, Nolan GP, Francis MB. Synthetically Modified Viral Capsids as Versatile Carriers for Use in Antibody-based Cell Targeting. Bioconjugate Chemistry. PMID 26076186 DOI: 10.1021/Acs.Bioconjchem.5B00226 |
0.338 |
|
| 2015 |
O'Gorman WE, Hsieh EW, Savig ES, Gherardini PF, Hernandez JD, Hansmann L, Balboni IM, Utz PJ, Bendall SC, Fantl WJ, Lewis DB, Nolan GP, Davis MM. Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus. The Journal of Allergy and Clinical Immunology. PMID 26037552 DOI: 10.1016/J.Jaci.2015.04.008 |
0.317 |
|
| 2015 |
Nair N, Mei HE, Chen SY, Hale M, Nolan GP, Maecker HT, Genovese M, Fathman CG, Whiting CC. Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy. Arthritis Research & Therapy. 17: 127. PMID 25981462 DOI: 10.1186/S13075-015-0644-Z |
0.363 |
|
| 2015 |
Kubagawa H, Carroll MC, Jacob CO, Lang KS, Lee KH, Mak T, McAndrews M, Morse HC, Nolan GP, Ohno H, Richter GH, Seal R, Wang JY, Wiestner A, Coligan JE. Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR. Journal of Immunology (Baltimore, Md. : 1950). 194: 4055-7. PMID 25888699 DOI: 10.4049/Jimmunol.1500222 |
0.3 |
|
| 2015 |
Lujan E, Zunder ER, Ng YH, Goronzy IN, Nolan GP, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 521: 352-6. PMID 25830878 DOI: 10.1038/Nature14274 |
0.45 |
|
| 2015 |
Nishikii H, Kanazawa Y, Umemoto T, Goltsev Y, Matsuzaki Y, Matsushita K, Yamato M, Nolan GP, Negrin R, Chiba S. Unipotent Megakaryopoietic Pathway Bridging Hematopoietic Stem Cells and Mature Megakaryocytes. Stem Cells (Dayton, Ohio). 33: 2196-207. PMID 25753067 DOI: 10.1002/Stem.1985 |
0.394 |
|
| 2015 |
Zunder ER, Lujan E, Goltsev Y, Wernig M, Nolan GP. A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. Cell Stem Cell. 16: 323-37. PMID 25748935 DOI: 10.1016/J.Stem.2015.01.015 |
0.397 |
|
| 2015 |
Zunder ER, Finck R, Behbehani GK, Amir el-AD, Krishnaswamy S, Gonzalez VD, Lorang CG, Bjornson Z, Spitzer MH, Bodenmiller B, Fantl WJ, Pe'er D, Nolan GP. Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm. Nature Protocols. 10: 316-33. PMID 25612231 DOI: 10.1038/Nprot.2015.020 |
0.376 |
|
| 2015 |
McIlwain DR, Grusdat M, Pozdeev VI, Xu HC, Shinde P, Reardon C, Hao Z, Beyer M, Bergthaler A, Häussinger D, Nolan GP, Lang KS, Lang PA. T-cell STAT3 is required for the maintenance of humoral immunity to LCMV. European Journal of Immunology. 45: 418-27. PMID 25393615 DOI: 10.1002/Eji.201445060 |
0.388 |
|
| 2015 |
Sarno J, Davis KL, Savino AM, Bugarin C, Pinto S, Buracchi C, Jager A, Palmi C, Barber RC, Silvestri D, Cazzaniga G, Dyer MJ, Biondi A, Nolan GP, Gaipa G. Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Blood. 126: 906-906. DOI: 10.1182/Blood.V126.23.906.906 |
0.455 |
|
| 2015 |
Davis KL, Sarno J, Biondi A, Jager A, Gaipa G, Good Z, Nolan GP. Increased Frequency of Cells with Activated Ribosomal Protein S6 at Diagnosis Associates with MRD Positivity and Relapse in Childhood BCP ALL Blood. 126: 2616-2616. DOI: 10.1182/Blood.V126.23.2616.2616 |
0.469 |
|
| 2015 |
Savino AM, Sarno J, Trentin L, Vieri M, Fazio G, Bardini M, Bugarin C, Fossati G, Davis KL, Gaipa G, Meyer LH, Nolan GP, Biondi A, Te Kronnie G, Palmi C, et al. Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia Blood. 126: 2534-2534. DOI: 10.1182/Blood.V126.23.2534.2534 |
0.432 |
|
| 2015 |
Levine JH, Simonds EF, Bendall SC, Nolan GP, Pe'er D. Abstract A32: Computational dissection of phenotypic and functional heterogeneity in acute myeloid leukemia. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A32 |
0.741 |
|
| 2015 |
Simonds EF, Nolan GP, Weiss WA. Abstract 2313: Characterizing intratumoral cellular heterogeneity in human glioblastoma xenografts by 30+ parameter single-cell mass cytometry Cancer Research. 75: 2313-2313. DOI: 10.1158/1538-7445.Am2015-2313 |
0.791 |
|
| 2014 |
Mingueneau M, Krishnaswamy S, Spitzer MH, Bendall SC, Stone EL, Hedrick SM, Pe'er D, Mathis D, Nolan GP, Benoist C. Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 16466-71. PMID 25362052 DOI: 10.1073/Pnas.1419337111 |
0.441 |
|
| 2014 |
Krishnaswamy S, Spitzer MH, Mingueneau M, Bendall SC, Litvin O, Stone E, Pe'er D, Nolan GP. Systems biology. Conditional density-based analysis of T cell signaling in single-cell data. Science (New York, N.Y.). 346: 1250689. PMID 25342659 DOI: 10.1126/Science.1250689 |
0.485 |
|
| 2014 |
Sachs Z, LaRue RS, Nguyen HT, Sachs K, Noble KE, Mohd Hassan NA, Diaz-Flores E, Rathe SK, Sarver AL, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon KM, Largaespada DA. NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia. Blood. 124: 3274-83. PMID 25316678 DOI: 10.1182/Blood-2013-08-521708 |
0.374 |
|
| 2014 |
Behbehani GK, Thom C, Zunder ER, Finck R, Gaudilliere B, Fragiadakis GK, Fantl WJ, Nolan GP. Transient partial permeabilization with saponin enables cellular barcoding prior to surface marker staining. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 1011-9. PMID 25274027 DOI: 10.1002/Cyto.A.22573 |
0.315 |
|
| 2014 |
Gaudillière B, Fragiadakis GK, Bruggner RV, Nicolau M, Finck R, Tingle M, Silva J, Ganio EA, Yeh CG, Maloney WJ, Huddleston JI, Goodman SB, Davis MM, Bendall SC, Fantl WJ, ... ... Nolan GP, et al. Clinical recovery from surgery correlates with single-cell immune signatures. Science Translational Medicine. 6: 255ra131. PMID 25253674 DOI: 10.1126/Scitranslmed.3009701 |
0.365 |
|
| 2014 |
Sen N, Mukherjee G, Sen A, Bendall SC, Sung P, Nolan GP, Arvin AM. Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus. Cell Reports. 8: 633-45. PMID 25043183 DOI: 10.1016/J.Celrep.2014.06.024 |
0.414 |
|
| 2014 |
Pyne S, Lee SX, Wang K, Irish J, Tamayo P, Nazaire MD, Duong T, Ng SK, Hafler D, Levy R, Nolan GP, Mesirov J, McLachlan GJ. Joint modeling and registration of cell populations in cohorts of high-dimensional flow cytometric data. Plos One. 9: e100334. PMID 24983991 DOI: 10.1371/Journal.Pone.0100334 |
0.553 |
|
| 2014 |
Bruggner RV, Bodenmiller B, Dill DL, Tibshirani RJ, Nolan GP. Automated identification of stratifying signatures in cellular subpopulations. Proceedings of the National Academy of Sciences of the United States of America. 111: E2770-7. PMID 24979804 DOI: 10.1073/Pnas.1408792111 |
0.433 |
|
| 2014 |
Bendall SC, Davis KL, Amir el-AD, Tadmor MD, Simonds EF, Chen TJ, Shenfeld DK, Nolan GP, Pe'er D. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Cell. 157: 714-25. PMID 24766814 DOI: 10.1016/J.Cell.2014.04.005 |
0.735 |
|
| 2014 |
Fienberg HG, Nolan GP. Mass cytometry to decipher the mechanism of nongenetic drug resistance in cancer. Current Topics in Microbiology and Immunology. 377: 85-94. PMID 24578267 DOI: 10.1007/82_2014_365 |
0.345 |
|
| 2014 |
Wolchinsky R, Hod-Marco M, Oved K, Shen-Orr SS, Bendall SC, Nolan GP, Reiter Y. Antigen-dependent integration of opposing proximal TCR-signaling cascades determines the functional fate of T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 192: 2109-19. PMID 24489091 DOI: 10.4049/Jimmunol.1301142 |
0.386 |
|
| 2014 |
Davis KL, Samusik N, Jager A, Bendall SC, Simonds EF, Fantl WJ, Nolan GP. Single Cell Developmental Classification of B Cell Precursor Acute Lymphoblastic Leukemia (BCP ALL) Reveals Link Between Phenotype, Signaling, and Drug Response Blood. 124: 488-488. DOI: 10.1182/Blood.V124.21.488.488 |
0.744 |
|
| 2014 |
Behbehani GK, Fantl WJ, Medeiros BC, Nolan GP. Mass Cytometric Analysis of AML Stem and Early Progenitor Cells Reveals Karyotype and Genotype-Specific Immunophenotypes That May Represent Targets for Antibody-Directed Therapies Blood. 124: 2380-2380. DOI: 10.1182/Blood.V124.21.2380.2380 |
0.358 |
|
| 2014 |
Behbehani GK, Fantl WJ, Medeiros BC, Nolan GP. Mass Cytometric Analysis of AML Stem and Early Progenitor Cells Reveals Karyotype and Genotype-Specific Cell Cycle Properties That Correlate with Known Responses to Chemotherapy Blood. 124: 2359-2359. DOI: 10.1182/Blood.V124.21.2359.2359 |
0.427 |
|
| 2014 |
Behbehani GK, Finck R, Samusik N, Gherardini PF, Sridhar KJ, Fantl WJ, Greenberg PL, Nolan GP. Profiling Myelodysplastic Syndromes By Mass Cytometry Demonstrates Distinct Immunophenotypic Aberrancies in Stem and Progenitor Populations Blood. 124: 1903-1903. DOI: 10.1182/Blood.V124.21.1903.1903 |
0.359 |
|
| 2014 |
Fisher DA, Malkova O, Fulbright MC, Behbehani GK, Nolan GP, Oh ST. Single Cell Mass Cytometry Reveals Hyperactivated Signaling Networks in Myeloproliferative Neoplasms Blood. 124: 1884-1884. DOI: 10.1182/Blood.V124.21.1884.1884 |
0.431 |
|
| 2014 |
Sachs Z, LaRue RS, Nguyen HT, Sachs K, Hassan NAM, Diaz-Flores E, Rathe SK, Sarver AL, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon KM, Largaespada DA. Abstract B15: NRASG12V oncogene mediates self-renewal in a murine model of acute myelogenous leukemia Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B15 |
0.391 |
|
| 2014 |
Krishnaswamy S, Spitzer MH, Mingueneau M, Bendall SC, Litvin O, Stone E, Pe'Er D, Nolan GP. Conditional density-based analysis of T cell signaling in single-cell data Science. 346. DOI: 10.1126/science/1250689 |
0.305 |
|
| 2014 |
Hsieh E, O'Gorman W, Savig E, Gherardini PF, Davis M, Nolan G. High Dimensional Single-Cell Mass Cytometry Demonstrates Conserved Human Toll-Like-Receptor Activation Signatures Journal of Allergy and Clinical Immunology. 133: AB244. DOI: 10.1016/J.Jaci.2013.12.869 |
0.346 |
|
| 2014 |
Nolan G. A single cell systems-based view of immunology and cancer Experimental Hematology. 42: S9. DOI: 10.1016/J.Exphem.2014.07.030 |
0.332 |
|
| 2013 |
Kinoshita SM, Kogure A, Taguchi S, Nolan GP. Snapin, positive regulator of stimulation- induced Ca²⁺ release through RyR, is necessary for HIV-1 replication in T cells. Plos One. 8: e75297. PMID 24130701 DOI: 10.1371/Journal.Pone.0075297 |
0.342 |
|
| 2013 |
Bjornson ZB, Nolan GP, Fantl WJ. Single-cell mass cytometry for analysis of immune system functional states. Current Opinion in Immunology. 25: 484-94. PMID 23999316 DOI: 10.1016/J.Coi.2013.07.004 |
0.436 |
|
| 2013 |
Gopinath S, Hotson A, Johns J, Nolan G, Monack D. The systemic immune state of super-shedder mice is characterized by a unique neutrophil-dependent blunting of TH1 responses. Plos Pathogens. 9: e1003408. PMID 23754944 DOI: 10.1371/Journal.Ppat.1003408 |
0.322 |
|
| 2013 |
Amir el-AD, Davis KL, Tadmor MD, Simonds EF, Levine JH, Bendall SC, Shenfeld DK, Krishnaswamy S, Nolan GP, Pe'er D. viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nature Biotechnology. 31: 545-52. PMID 23685480 DOI: 10.1038/Nbt.2594 |
0.701 |
|
| 2013 |
Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Best AJ, et al. The transcriptional landscape of αβ T cell differentiation. Nature Immunology. 14: 619-32. PMID 23644507 DOI: 10.1038/Ni.2590 |
0.391 |
|
| 2013 |
Nolan G. Inner-outer beauty: DNA-binding surface tags as cellular barcodes Nature Methods. 10: 399-401. PMID 23629416 DOI: 10.1038/Nmeth.2452 |
0.337 |
|
| 2013 |
Finck R, Simonds EF, Jager A, Krishnaswamy S, Sachs K, Fantl W, Pe'er D, Nolan GP, Bendall SC. Normalization of mass cytometry data with bead standards. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 483-94. PMID 23512433 DOI: 10.1002/Cyto.A.22271 |
0.695 |
|
| 2013 |
Nolan G. All Roads Lead to Rome: Phenotypic Channeling to Uniform Differentiation Structures from Diverse Leukemia Genotypes by Mass Cytometry Blood. 122: SCI-22-SCI-22. DOI: 10.1182/Blood.V122.21.Sci-22.Sci-22 |
0.438 |
|
| 2013 |
LaRue RS, Nguyen H, Sachs K, Mohd Hassan NA, Diaz-Flores E, Rathe SK, Sarver AG, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon K, Sachs Z, Largaespada DA. Ras-Pathway Inhibition With Targeted Therapies Abrogates Self-Renewal In Acute Myelogenous Leukemia Blood. 122: 819-819. DOI: 10.1182/Blood.V122.21.819.819 |
0.394 |
|
| 2013 |
Fisher DA, Behbehani GK, Nolan GP, Bendall SC, Oh ST. Mass Cytometry Analysis Of Myelofibrosis and Secondary Acute Myeloid Leukemia Reveals Constitutive and Cytokine Induced Signaling Abnormalities With Differential Sensitivities To Ruxolitinib Blood. 122: 1610-1610. DOI: 10.1182/Blood.V122.21.1610.1610 |
0.469 |
|
| 2013 |
Amir ED, Litvin O, Levine J, Bendall SC, Davis KL, Simonds EF, Schild T, Rocco M, Rosen N, Nolan GP, Pe'er D. Abstract IA30: Towards rationale therapy: Dealing with intertumor and intratumor heterogeneity Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia30 |
0.756 |
|
| 2013 |
Simonds EF, Bendall SC, Gedman AL, Levine JH, Davis KL, Fienberg HG, Jager A, Amir ED, Radtke I, Fantl WJ, Pe'er D, Downing JR, Nolan GP. Abstract 3178: Deep sequencing of immunophenotypically distinct subsets in acute myeloid leukemia reveals reservoirs of genetically distinct subclones along a conserved differentiation trajectory. Cancer Research. 73: 3178-3178. DOI: 10.1158/1538-7445.Am2013-3178 |
0.706 |
|
| 2013 |
Sen N, Mukherjee G, Bendall SC, Sen A, Jager A, Sung P, Nolan GP, Johnstone I, Arvin AM. 233 Cytokine. 63: 298. DOI: 10.1016/J.Cyto.2013.06.236 |
0.414 |
|
| 2012 |
Kinoshita SM, Krutzik PO, Nolan GP. COP9 signalosome component JAB1/CSN5 is necessary for T cell signaling through LFA-1 and HIV-1 replication. Plos One. 7: e41725. PMID 22911848 DOI: 10.1371/Journal.Pone.0041725 |
0.7 |
|
| 2012 |
Bodenmiller B, Zunder ER, Finck R, Chen TJ, Savig ES, Bruggner RV, Simonds EF, Bendall SC, Sachs K, Krutzik PO, Nolan GP. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nature Biotechnology. 30: 858-67. PMID 22902532 DOI: 10.1038/Nbt.2317 |
0.817 |
|
| 2012 |
Linderman MD, Bjornson Z, Simonds EF, Qiu P, Bruggner RV, Sheode K, Meng TH, Plevritis SK, Nolan GP. CytoSPADE: high-performance analysis and visualization of high-dimensional cytometry data. Bioinformatics (Oxford, England). 28: 2400-1. PMID 22782546 DOI: 10.1093/Bioinformatics/Bts425 |
0.671 |
|
| 2012 |
Bendall SC, Nolan GP. From single cells to deep phenotypes in cancer. Nature Biotechnology. 30: 639-47. PMID 22781693 DOI: 10.1038/Nbt.2283 |
0.444 |
|
| 2012 |
Behbehani GK, Bendall SC, Clutter MR, Fantl WJ, Nolan GP. Single-cell mass cytometry adapted to measurements of the cell cycle. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 552-66. PMID 22693166 DOI: 10.1002/Cyto.A.22075 |
0.433 |
|
| 2012 |
Fienberg HG, Simonds EF, Fantl WJ, Nolan GP, Bodenmiller B. A platinum-based covalent viability reagent for single-cell mass cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 467-75. PMID 22577098 DOI: 10.1002/Cyto.A.22067 |
0.702 |
|
| 2012 |
Bendall SC, Nolan GP, Roederer M, Chattopadhyay PK. A deep profiler's guide to cytometry. Trends in Immunology. 33: 323-32. PMID 22476049 DOI: 10.1016/J.It.2012.02.010 |
0.431 |
|
| 2012 |
Schulz KR, Danna EA, Krutzik PO, Nolan GP. Single-cell phospho-protein analysis by flow cytometry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 8.17.1-20. PMID 22314834 DOI: 10.1002/0471142735.Im0817S96 |
0.773 |
|
| 2012 |
Gibbs KD, Jager A, Crespo O, Goltsev Y, Trejo A, Richard CE, Nolan GP. Decoupling of tumor-initiating activity from stable immunophenotype in HoxA9-Meis1-driven AML. Cell Stem Cell. 10: 210-7. PMID 22305570 DOI: 10.1016/J.Stem.2012.01.004 |
0.379 |
|
| 2012 |
Newell EW, Sigal N, Bendall SC, Nolan GP, Davis MM. Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. Immunity. 36: 142-52. PMID 22265676 DOI: 10.1016/J.Immuni.2012.01.002 |
0.398 |
|
| 2012 |
Fisher DA, Simonds EF, Behbehani GK, Nolan GP, Bendall SC, Oh ST. Single Cell Mass Cytometry of Dysregulated Signaling Networks in Myeloproliferative Neoplasms and Secondary Acute Myeloid Leukemia Blood. 120: 703-703. DOI: 10.1182/Blood.V120.21.703.703 |
0.76 |
|
| 2012 |
Sachs Z, Nguyen H, Hassan NAM, Rathe SK, Sachs K, Diaz-Flores E, Bendall SC, Diers MD, Nolan GP, Shannon KM, Largaespada DA. Activated NRAS Mediates Self-Renewal Capacity in AML by Facilitating the Mll/AF9-Specified Gene Expression Signature Blood. 120: 5116-5116. DOI: 10.1182/Blood.V120.21.5116.5116 |
0.356 |
|
| 2012 |
Knapp DJ, Bendall SC, Miller PH, Cheung AM, Imren S, Humphries RK, Brinkman RR, Oostendorp RA, Nolan GP, Eaves CJ. Short Term Signalling Responses of the Most Primitive Subsets of Human Hematopoietic Cells Stimulated in Vitro Correlate with Their Subsequent Self-Renewal Behaviour. Blood. 120: 2341-2341. DOI: 10.1182/Blood.V120.21.2341.2341 |
0.458 |
|
| 2012 |
Bendall SC, Amir ED, Tadmor M, Davis KL, Simonds EF, Shenfeld D, Levine J, Nolan GP, Pe'er D. Dimensionality Reduction Reveals Distinct Shapes of Normal and Malignant Hematopoietic Cell Populations Blood. 120: 1451-1451. DOI: 10.1182/Blood.V120.21.1451.1451 |
0.739 |
|
| 2012 |
Sachs K, Nolan GP, Fantl WJ, Simonds EF, Bendall SC, Davis KL. Network-Based Discovery of Prognostic Markers in Pediatric AML by Multi-Dimensional Single Cell Mass Cytometry Blood. 120: 1411-1411. DOI: 10.1182/Blood.V120.21.1411.1411 |
0.713 |
|
| 2012 |
Davis KL, Bendall SC, Amir ED, Simonds EF, Jager A, Trejo A, Pe'er D, Nolan GP. Single Cell Trajectory Detection Orders Hallmarks of Early Human B Cell Development Blood. 120: 1044-1044. DOI: 10.1182/Blood.V120.21.1044.1044 |
0.743 |
|
| 2012 |
Neel BG, Stewart JM, Bodenmiller B, Ailles L, Gedye C, Bernardini M, Shaw PA, Fantl W, Nolan GP. Abstract SY35-02: Phenotypic heterogeneity and instability of human serous ovarian cancer tumor-initiating cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy35-02 |
0.445 |
|
| 2012 |
Hsu F, Nolan GP, Chen T, Goltsev Y. Abstract LB-33: Identification of two unrecognized acute myeloid leukemia (AML) subtypes based on cell by cell analysis of leukemic blasts Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-33 |
0.403 |
|
| 2012 |
Gibbs KD, Jager A, Crespo O, Goltsev Y, Tejo A, Richard C, Nolan G. Abstract 3307: Improved survival in AML by in vivo drug targeting of conserved regulatory pathways in phenotypically distinct tumor-initiating compartments Cancer Research. 72: 3307-3307. DOI: 10.1158/1538-7445.Am2012-3307 |
0.406 |
|
| 2012 |
Gaudillière B, Schubert R, Nolan G, Angst M. Multiparameter flow cytometry analysis of opioid-mediated alteration of human immune signaling pathways European Journal of Anaesthesiology. 29: 137-138. DOI: 10.1097/00003643-201206001-00451 |
0.321 |
|
| 2011 |
Nolan GP. Flow cytometry in the post fluorescence era. Best Practice & Research. Clinical Haematology. 24: 505-8. PMID 22127312 DOI: 10.1016/J.Beha.2011.09.005 |
0.408 |
|
| 2011 |
Palazzo AL, Evensen E, Huang YW, Cesano A, Nolan GP, Fantl WJ. Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells Plos One. 6. PMID 22016760 DOI: 10.1371/Journal.Pone.0024592 |
0.43 |
|
| 2011 |
Qiu P, Simonds EF, Bendall SC, Gibbs KD, Bruggner RV, Linderman MD, Sachs K, Nolan GP, Plevritis SK. Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nature Biotechnology. 29: 886-91. PMID 21964415 DOI: 10.1038/Nbt.1991 |
0.724 |
|
| 2011 |
Knijnenburg TA, Roda O, Wan Y, Nolan GP, Aitchison JD, Shmulevich I. A regression model approach to enable cell morphology correction in high-throughput flow cytometry. Molecular Systems Biology. 7: 531. PMID 21952134 DOI: 10.1038/Msb.2011.64 |
0.432 |
|
| 2011 |
Heffner GC, Clutter MR, Nolan GP, Weissman IL. Novel hematopoietic progenitor populations revealed by direct assessment of GATA1 protein expression and cMPL signaling events. Stem Cells (Dayton, Ohio). 29: 1774-82. PMID 21898686 DOI: 10.1002/Stem.719 |
0.444 |
|
| 2011 |
Thomas C, Moraga I, Levin D, Krutzik PO, Podoplelova Y, Trejo A, Lee C, Yarden G, Vleck SE, Glenn JS, Nolan GP, Piehler J, Schreiber G, Garcia KC. Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell. 146: 621-32. PMID 21854986 DOI: 10.1016/J.Cell.2011.06.048 |
0.688 |
|
| 2011 |
Bendall SC, Simonds EF, Qiu P, Amir el-AD, Krutzik PO, Finck R, Bruggner RV, Melamed R, Trejo A, Ornatsky OI, Balderas RS, Plevritis SK, Sachs K, Pe'er D, Tanner SD, ... Nolan GP, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science (New York, N.Y.). 332: 687-96. PMID 21551058 DOI: 10.1126/Science.1198704 |
0.839 |
|
| 2011 |
Gibbs KD, Gilbert PM, Sachs K, Zhao F, Blau HM, Weissman IL, Nolan GP, Majeti R. Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments. Blood. 117: 4226-33. PMID 21357764 DOI: 10.1182/Blood-2010-07-298232 |
0.454 |
|
| 2011 |
Krutzik PO, Clutter MR, Trejo A, Nolan GP. Fluorescent cell barcoding for multiplex flow cytometry. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 6.31. PMID 21207359 DOI: 10.1002/0471142956.Cy0631S55 |
0.716 |
|
| 2011 |
Krutzik PO, Trejo A, Schulz KR, Nolan GP. Phospho flow cytometry methods for the analysis of kinase signaling in cell lines and primary human blood samples. Methods in Molecular Biology (Clifton, N.J.). 699: 179-202. PMID 21116984 DOI: 10.1007/978-1-61737-950-5_9 |
0.768 |
|
| 2011 |
Davis KL, Simonds EF, Bendall SC, Fantl WJ, Nolan GP. Mass Cytometry Organizes the Heterogeneity of Pediatric B Cell Acute Lymphoblastic Leukemia Blood. 118: 753-753. DOI: 10.1182/Blood.V118.21.753.753 |
0.746 |
|
| 2011 |
Behbehani GK, Bendall SC, Clutter M, Medeiros BC, Fantl WJ, Nolan GP. Application of Mass Cytometry to Measure Proliferation During Normal and Malignant Hematopoietic Differentiation Blood. 118: 4782-4782. DOI: 10.1182/Blood.V118.21.4782.4782 |
0.477 |
|
| 2011 |
Simonds EF, Bendall SC, Davis KL, Fienberg HG, Finck RL, Amir ED, Radtke I, Downing JR, Pe'er D, Nolan GP. Signaling and Immunophenotypic Diversity in Pediatric Acute Myeloid Leukemia As Defined by 31-Parameter Single-Cell Mass Cytometry Blood. 118: 2565-2565. DOI: 10.1182/Blood.V118.21.2565.2565 |
0.758 |
|
| 2011 |
Nolan GP. Abstract SY14-01: 34+ parameter single-cell mass cytometry of differential immune and drug responses across healthy human hematopoiesis and related malignancies Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy14-01 |
0.513 |
|
| 2010 |
Bodenmiller B, Wanka S, Kraft C, Urban J, Campbell D, Pedrioli PG, Gerrits B, Picotti P, Lam H, Vitek O, Brusniak MY, Roschitzki B, Zhang C, Shokat KM, Schlapbach R, ... ... Nolan GP, et al. Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast. Science Signaling. 3: rs4. PMID 21177495 DOI: 10.1126/Scisignal.2001182 |
0.386 |
|
| 2010 |
Katzman SD, O'Gorman WE, Villarino AV, Gallo E, Friedman RS, Krummel MF, Nolan GP, Abbas AK. Duration of antigen receptor signaling determines T-cell tolerance or activation. Proceedings of the National Academy of Sciences of the United States of America. 107: 18085-90. PMID 20921406 DOI: 10.1073/Pnas.1010560107 |
0.424 |
|
| 2010 |
Clutter MR, Heffner GC, Krutzik PO, Sachen KL, Nolan GP. Tyramide signal amplification for analysis of kinase activity by intracellular flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 1020-31. PMID 20824632 DOI: 10.1002/Cyto.A.20970 |
0.764 |
|
| 2010 |
Rosen DB, Putta S, Covey T, Huang YW, Nolan GP, Cesano A, Minden MD, Fantl WJ. Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia. Plos One. 5: e12405. PMID 20811632 DOI: 10.1371/Journal.Pone.0012405 |
0.344 |
|
| 2010 |
O'Gorman WE, Sampath P, Simonds EF, Sikorski R, O'Malley M, Krutzik PO, Chen H, Panchanathan V, Chaudhri G, Karupiah G, Lewis DB, Thorne SH, Nolan GP. Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses. Cell Host & Microbe. 8: 174-85. PMID 20709294 DOI: 10.1016/J.Chom.2010.07.008 |
0.789 |
|
| 2010 |
Irish JM, Myklebust JH, Alizadeh AA, Houot R, Sharman JP, Czerwinski DK, Nolan GP, Levy R. B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 12747-54. PMID 20543139 DOI: 10.1073/Pnas.1002057107 |
0.643 |
|
| 2010 |
Oh ST, Simonds EF, Jones C, Hale MB, Goltsev Y, Gibbs KD, Merker JD, Zehnder JL, Nolan GP, Gotlib J. Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. Blood. 116: 988-92. PMID 20404132 DOI: 10.1182/Blood-2010-02-270108 |
0.693 |
|
| 2010 |
Irish JM, Czerwinski DK, Nolan GP, Levy R. Clinical Translation of a Prognostic Follicular Lymphoma Signaling Profile Blood. 116: 636-636. DOI: 10.1182/Blood.V116.21.636.636 |
0.642 |
|
| 2010 |
Sachs Z, Diaz-Flores E, Diers MD, Sachs K, Bendall SC, Fienberg HG, Rathe SK, Nolan GP, Shannon K, Largaespada D. Oncogene Withdrawal Selectively Alters Phosphoprotein States and Shifts Differentiation Status In Myeloid Leukemia Subpopulations Blood. 116: 3160-3160. DOI: 10.1182/Blood.V116.21.3160.3160 |
0.493 |
|
| 2010 |
Oh ST, Zahn JM, Jones CD, Zhang B, Loh ML, Kantarjian H, Simonds EF, Bruggner RV, Abidi P, Natsoulis G, Bell J, Buenrostro J, Nolan GP, Zehnder JL, Ji HP, et al. Identification of Novel LNK Mutations In Patients with Chronic Myeloproliferative Neoplasms and Related Disorders Blood. 116: 315-315. DOI: 10.1182/Blood.V116.21.315.315 |
0.665 |
|
| 2010 |
Gotlib J, Zhang B, Jones CD, Riess J, Wong WB, Simonds EF, Hale MB, Abidi P, McClung J, Nolan GP, Oh ST, Zehnder JL. Identification of a Novel Splice Donor Mutation In the Thrombopoietin Gene In a Philippine Family with Hereditary Thrombocythemia Blood. 116: 3086-3086. DOI: 10.1182/Blood.V116.21.3086.3086 |
0.664 |
|
| 2010 |
Davis KL, Simonds EF, Bendall S, Nolan GP. High-Dimensional Analysis of Intracellular Signaling and Dasatinib Inhibition In High-Risk Pediatric Leukemia by 31-Parameter Mass Cytometry Blood. 116: 2761-2761. DOI: 10.1182/Blood.V116.21.2761.2761 |
0.744 |
|
| 2010 |
Nolan GP. Abstract SY19-03: Single-cell signaling and pathology in primary cell cancers for mechanism and diagnostics Cellular and Molecular Biology. 70. DOI: 10.1158/1538-7445.Am10-Sy19-03 |
0.505 |
|
| 2010 |
Rosen DB, Minden MD, Putta S, Covey T, Huang Y, Cesano A, Nolan GP, Fantl WJ. Abstract 3842: Identification of distinct apoptosis and myeloid signaling profiles within acute myeloid leukemia (AML) blast subpopulations Cancer Research. 70: 3842-3842. DOI: 10.1158/1538-7445.Am10-3842 |
0.411 |
|
| 2010 |
Oh ST, Simonds EF, Jones C, Hale MB, Goltsev Y, Gibbs KD, Merker JD, Zehnder JL, Nolan GP, Gotlib J. Abstract 239: Mutation of the inhibitory adaptor protein LNK drives potentiated JAK-STAT signaling in patients with JAK2 V617F-negative myeloproliferative neoplasms Cancer Research. 70: 239-239. DOI: 10.1158/1538-7445.Am10-239 |
0.692 |
|
| 2010 |
O'Donnell EA, Nolan GP, Engleman EG, Mende I. Abstract 1916: Robust pro-inflammatory cytokine secretion by tumor-infiltrating t cells despite altered Stat1/Stat3 signaling responses Cancer Research. 70: 1916-1916. DOI: 10.1158/1538-7445.Am10-1916 |
0.795 |
|
| 2010 |
Oh ST, Zahn JM, Simonds EF, Bell J, Natsoulis G, Buenstro J, Jones C, Hale MB, Goltsev Y, Gibbs KD, Merker JD, Zehnder JL, Davis RW, Nolan GP, Ji HP, et al. Abstract B6: Identification of novel mutations in the inhibitory adaptor protein LNK in patients with JAK2 V617F-negative and -positive chronic myeloproliferative neoplasms Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-B6 |
0.673 |
|
| 2010 |
Newell E, Bendall S, Hong D, Lewis D, Nolan G, Davis M. Surveying the Influenza-specific Cytotoxic T Cell Response in Humans and Mice Using Mass-cytometry (CyTOF) and Combinatorial Tetramer Staining Clinical Immunology. 135: S104. DOI: 10.1016/J.Clim.2010.03.312 |
0.331 |
|
| 2010 |
Hsu F, Irish J, Sachs K, Nolan G. Altered T Cell Antigen-specific Receptor Signaling in Tumor Infiltrating T Cells in Follicular Lymphomas Clinical Immunology. 135: S66. DOI: 10.1016/J.Clim.2010.03.202 |
0.58 |
|
| 2010 |
Krutzik PO, Bendall SC, Hale MB, Irish JM, Nolan GP. Phospho Flow Cytometry: Single-Cell Signaling Networks in Next-Generation Drug Discovery and Patient Stratification Flow Cytometry in Drug Discovery and Development. 303-334. DOI: 10.1002/9780470910085.ch15 |
0.755 |
|
| 2009 |
Sachs K, Gentles AJ, Youland R, Itani S, Irish J, Nolan GP, Plevritis SK. Characterization of patient specific signaling via augmentation of Bayesian networks with disease and patient state nodes. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 6624-7. PMID 19963681 DOI: 10.1109/IEMBS.2009.5332563 |
0.513 |
|
| 2009 |
Hale MB, Krutzik PO, Samra SS, Crane JM, Nolan GP. Stage dependent aberrant regulation of cytokine-STAT signaling in murine systemic lupus erythematosus. Plos One. 4: e6756. PMID 19707593 DOI: 10.1371/Journal.Pone.0006756 |
0.721 |
|
| 2009 |
O'Gorman WE, Dooms H, Thorne SH, Kuswanto WF, Simonds EF, Krutzik PO, Nolan GP, Abbas AK. The initial phase of an immune response functions to activate regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 332-9. PMID 19542444 DOI: 10.4049/Jimmunol.0900691 |
0.804 |
|
| 2009 |
Hotson AN, Hardy JW, Hale MB, Contag CH, Nolan GP. The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals. Journal of Immunology (Baltimore, Md. : 1950). 182: 7558-68. PMID 19494279 DOI: 10.4049/Jimmunol.0803666 |
0.413 |
|
| 2009 |
Shachaf CM, Elchuri SV, Koh AL, Zhu J, Nguyen LN, Mitchell DJ, Zhang J, Swartz KB, Sun L, Chan S, Sinclair R, Nolan GP. A novel method for detection of phosphorylation in single cells by surface enhanced Raman scattering (SERS) using composite organic-inorganic nanoparticles (COINs). Plos One. 4: e5206. PMID 19367337 DOI: 10.1371/Journal.Pone.0005206 |
0.319 |
|
| 2009 |
Almogy G, Nolan GP. Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression. Biotechniques. 46: 44-50. PMID 19301621 DOI: 10.2144/000113030 |
0.644 |
|
| 2009 |
Hammer MM, Kotecha N, Irish JM, Nolan GP, Krutzik PO. WebFlow: a software package for high-throughput analysis of flow cytometry data. Assay and Drug Development Technologies. 7: 44-55. PMID 19187010 DOI: 10.1089/Adt.2008.174 |
0.786 |
|
| 2009 |
Gibbs K, Gilbert P, Weissman IL, Blau HM, Nolan GP, Majeti R. Single Cell Phospho-Flow Analysis of Cytokine Stimulation in Human Hematopoietic Progenitors Reveals That G-CSF Acts Directly On Human Hematopoietic Stem Cells. Blood. 114: 3617-3617. DOI: 10.1182/Blood.V114.22.3617.3617 |
0.453 |
|
| 2008 |
Kotecha N, Flores NJ, Irish JM, Simonds EF, Sakai DS, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell. 14: 335-43. PMID 18835035 DOI: 10.1016/J.Ccr.2008.08.014 |
0.813 |
|
| 2008 |
Shachaf CM, Gentles AJ, Elchuri S, Sahoo D, Soen Y, Sharpe O, Perez OD, Chang M, Mitchel D, Robinson WH, Dill D, Nolan GP, Plevritis SK, Felsher DW. Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance Cancer Research. 68: 5132-5142. PMID 18593912 DOI: 10.1158/0008-5472.Can-07-6192 |
0.359 |
|
| 2008 |
Lee AW, Sharp ER, O'Mahony A, Rosenberg MG, Israelski DM, Nolan GP, Nixon DF. Single-cell, phosphoepitope-specific analysis demonstrates cell type- and pathway-specific dysregulation of Jak/STAT and MAPK signaling associated with in vivo human immunodeficiency virus type 1 infection. Journal of Virology. 82: 3702-12. PMID 18216116 DOI: 10.1128/Jvi.01582-07 |
0.395 |
|
| 2008 |
Krutzik PO, Crane JM, Clutter MR, Nolan GP. High-content single-cell drug screening with phosphospecific flow cytometry. Nature Chemical Biology. 4: 132-42. PMID 18157122 DOI: 10.1038/Nchembio.2007.59 |
0.741 |
|
| 2008 |
Irish JM, Houot R, Myklebust JH, Czerwinski DK, Nolan GP, Levy R. Signaling Diversity in Human Lymphoma B Cells and in Tumor Infiltrating T Cells Correlates with Follicular Lymphoma Patient Clinical Outcomes Blood. 112: 377-377. DOI: 10.1182/Blood.V112.11.377.377 |
0.643 |
|
| 2007 |
Schulz KR, Danna EA, Krutzik PO, Nolan GP. Single-cell phospho-protein analysis by flow cytometry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 8.17. PMID 18432997 DOI: 10.1002/0471142735.Im0817S78 |
0.774 |
|
| 2007 |
Shachaf CM, Perez OD, Youssef S, Fan AC, Elchuri S, Goldstein MJ, Shirer AE, Sharpe O, Chen J, Mitchell DJ, Chang M, Nolan GP, Steinman L, Felsher DW. Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis. Blood. 110: 2674-84. PMID 17622571 DOI: 10.1182/Blood-2006-09-048033 |
0.312 |
|
| 2007 |
Nolan GP. What's wrong with drug screening today. Nature Chemical Biology. 3: 187-91. PMID 17372598 DOI: 10.1038/Nchembio0407-187 |
0.318 |
|
| 2007 |
Lehár J, Zimmermann GR, Krueger AS, Molnar RA, Ledell JT, Heilbut AM, Short GF, Giusti LC, Nolan GP, Magid OA, Lee MS, Borisy AA, Stockwell BR, Keith CT. Chemical combination effects predict connectivity in biological systems. Molecular Systems Biology. 3: 80. PMID 17332758 DOI: 10.1038/Msb4100116 |
0.318 |
|
| 2007 |
Perez OD, Mitchell D, Nolan GP. Differential role of ICAM ligands in determination of human memory T cell differentiation Bmc Immunology. 8. PMID 17233909 DOI: 10.1186/1471-2172-8-2 |
0.397 |
|
| 2007 |
Van Meter ME, Díaz-Flores E, Archard JA, Passegué E, Irish JM, Kotecha N, Nolan GP, Shannon K, Braun BS. K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells. Blood. 109: 3945-52. PMID 17192389 DOI: 10.1182/Blood-2006-09-047530 |
0.784 |
|
| 2007 |
Bjørndal B, Myklebust LM, Rosendal KR, Myromslien FD, Lorens JB, Nolan G, Bruland O, Lillehaug JR. RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells. International Journal of Cancer. 120: 961-9. PMID 17149700 DOI: 10.1002/Ijc.22373 |
0.332 |
|
| 2007 |
Zampieri CA, Fortin JF, Nolan GP, Nabel GJ. The ERK mitogen-activated protein kinase pathway contributes to Ebola virus glycoprotein-induced cytotoxicity. Journal of Virology. 81: 1230-40. PMID 17108034 DOI: 10.1128/Jvi.01586-06 |
0.405 |
|
| 2007 |
Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT. Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53. Blood. 109: 2589-96. PMID 17105820 DOI: 10.1182/Blood-2006-02-004234 |
0.576 |
|
| 2007 |
Kotecha N, Flores NJ, Irish JM, Sakaguchi D, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML. A Novel Assay for Juvenile Myelomonocytic Leukemia Based on Aberrant Signaling Networks Measured Via Phospho-Specific Flow Cytometry Reduces Diagnosis Time from Weeks to Days. Blood. 110: 546-546. DOI: 10.1182/Blood.V110.11.546.546 |
0.799 |
|
| 2007 |
Irish JM, Hsu FY, Sharman JP, Houot R, Brody JD, Czerwinski DK, Nolan GP, Levy R. A Profile of 648 Signaling Network Events Identifies Cell Subsets with Diverse, Abnormal Responses to Lymphocyte Stimuli within Follicular Lymphoma Tumors. Blood. 110: 356-356. DOI: 10.1182/Blood.V110.11.356.356 |
0.629 |
|
| 2007 |
Hale M, Krutzik P, Nolan G. Cell-type Specific Changes in Cytokine-STAT Signal Transduction Stage Systemic Lupus Erythematosus Clinical Immunology. 123: S138-S139. DOI: 10.1016/J.Clim.2007.03.032 |
0.712 |
|
| 2007 |
Nolan G. Visualizing Inside the Cell Biology of Blood and Marrow Transplantation. 13: 120-123. DOI: 10.1016/J.Bbmt.2006.11.010 |
0.308 |
|
| 2006 |
Nolan GP. Deeper insights into hematological oncology disorders via single-cell phospho-signaling analysis. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 123-7, 509. PMID 17124050 DOI: 10.1182/Asheducation-2006.1.123 |
0.465 |
|
| 2006 |
He XS, Ji X, Hale MB, Cheung R, Ahmed A, Guo Y, Nolan GP, Pfeffer LM, Wright TL, Risch N, Tibshirani R, Greenberg HB. Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology (Baltimore, Md.). 44: 352-9. PMID 16871572 DOI: 10.1002/Hep.21267 |
0.309 |
|
| 2006 |
Marks KM, Nolan GP. Chemical labeling strategies for cell biology. Nature Methods. 3: 591-6. PMID 16862131 DOI: 10.1038/Nmeth906 |
0.597 |
|
| 2006 |
Irish JM, Czerwinski DK, Nolan GP, Levy R. Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 177: 1581-9. PMID 16849466 DOI: 10.4049/Jimmunol.177.3.1581 |
0.632 |
|
| 2006 |
Irish JM, Czerwinski DK, Nolan GP, Levy R. Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Blood. 108: 3135-42. PMID 16835385 DOI: 10.1182/Blood-2006-02-003921 |
0.617 |
|
| 2006 |
Hale MB, Nolan GP. Phospho-specific flow cytometry: intersection of immunology and biochemistry at the single-cell level. Current Opinion in Molecular Therapeutics. 8: 215-24. PMID 16774041 |
0.304 |
|
| 2006 |
Krutzik PO, Nolan GP. Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling. Nature Methods. 3: 361-8. PMID 16628206 DOI: 10.1038/Nmeth872 |
0.759 |
|
| 2006 |
Perez OD, Nolan GP. Phospho-proteomic immune analysis by flow cytometry: From mechanism to translational medicine at the single-cell level Immunological Reviews. 210: 208-228. PMID 16623773 DOI: 10.1111/J.0105-2896.2006.00364.X |
0.365 |
|
| 2006 |
Wehrman TS, von Degenfeld G, Krutzik PO, Nolan GP, Blau HM. Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Nature Methods. 3: 295-301. PMID 16554835 DOI: 10.1038/Nmeth868 |
0.662 |
|
| 2006 |
Irish JM, Kotecha N, Nolan GP. Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nature Reviews. Cancer. 6: 146-55. PMID 16491074 DOI: 10.1038/Nrc1804 |
0.793 |
|
| 2006 |
Danna EA, Nolan GP. Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level. Current Opinion in Chemical Biology. 10: 20-7. PMID 16406766 DOI: 10.1016/J.Cbpa.2005.12.021 |
0.353 |
|
| 2005 |
Clutter MR, Krutzik PO, Nolan GP. Phospho-specific flow cytometry in drug discovery. Drug Discovery Today. Technologies. 2: 295-302. PMID 24981951 DOI: 10.1016/J.Ddtec.2005.08.010 |
0.69 |
|
| 2005 |
Perez OD, Mitchell D, Campos R, Gao GJ, Li L, Nolan GP. Multiparameter analysis of intracellular phosphoepitopes in immunophenotyped cell populations by flow cytometry. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 6.20. PMID 18770823 DOI: 10.1002/0471142956.Cy0620S32 |
0.473 |
|
| 2005 |
Schaap A, Fortin JF, Sommer M, Zerboni L, Stamatis S, Ku CC, Nolan GP, Arvin AM. T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection. Journal of Virology. 79: 12921-33. PMID 16188994 DOI: 10.1128/Jvi.79.20.12921-12933.2005 |
0.389 |
|
| 2005 |
Krutzik PO, Hale MB, Nolan GP. Characterization of the murine immunological signaling network with phosphospecific flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 175: 2366-73. PMID 16081807 DOI: 10.4049/Jimmunol.175.4.2366 |
0.764 |
|
| 2005 |
Krutzik PO, Clutter MR, Nolan GP. Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 175: 2357-65. PMID 16081806 DOI: 10.4049/Jimmunol.175.4.2357 |
0.74 |
|
| 2005 |
Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP. Causal protein-signaling networks derived from multiparameter single-cell data. Science (New York, N.Y.). 308: 523-9. PMID 15845847 DOI: 10.1126/Science.1105809 |
0.417 |
|
| 2005 |
Berquin IM, Pang B, Dziubinski ML, Scott LM, Chen YQ, Nolan GP, Ethier SP. Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells. Oncogene. 24: 3177-86. PMID 15735691 DOI: 10.1038/Sj.Onc.1208504 |
0.337 |
|
| 2005 |
Stitz J, Krutzik PO, Nolan GP. Screening of retroviral cDNA libraries for factors involved in protein phosphorylation in signaling cascades. Nucleic Acids Research. 33: e39. PMID 15731332 DOI: 10.1093/Nar/Gni039 |
0.748 |
|
| 2005 |
Wolkowicz R, Jager GC, Nolan GP. A random peptide library fused to CCR5 for selection of mimetopes expressed on the mammalian cell surface via retroviral vectors. The Journal of Biological Chemistry. 280: 15195-201. PMID 15657029 DOI: 10.1074/Jbc.M500254200 |
0.364 |
|
| 2005 |
Irish J, Hovland R, Krutzik P, Perez O, Bruserud O, Gjertsen B, Nolan G. Potentiated phospho-protein networks in cancer cells Breast Cancer Research. 7: 1-1. DOI: 10.1186/Bcr1194 |
0.778 |
|
| 2005 |
Irish JM, Czerwinski DK, Nolan GP, Levy R. Rapid, Sustained B Cell Receptor Signaling in Lymphoma B Cells Differs from Normal Signaling in Tumor Infiltrating Nonmalignant B Cells. Blood. 106: 283-283. DOI: 10.1182/Blood.V106.11.283.283 |
0.623 |
|
| 2005 |
Van Meter ME, Diaz-Flores E, Archard JA, Kotecha N, Sabnis AJ, Irish JM, Nolan GP, Shannon KM, Braun BS. Multiparameter Flow Cytometric Analysis Reveals Aberrant Phosphorylation of a Network of Effector Molecules in Defined Populations of Kras Mutant Bone Marrow. Blood. 106: 239-239. DOI: 10.1182/Blood.V106.11.239.239 |
0.776 |
|
| 2005 |
Shai E, Condiotti R, Curran MA, Nolan GP, Galun E. 837. Prolonged Gene Expression in Murine Salivary Glands Following FIV-Based Lentiviral Vector Transduction Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.380 |
0.571 |
|
| 2004 |
Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, Gjertsen BT, Nolan GP. Single cell profiling of potentiated phospho-protein networks in cancer cells Cell. 118: 217-228. PMID 15260991 DOI: 10.1016/J.Cell.2004.06.028 |
0.779 |
|
| 2004 |
Condiotti R, Curran MA, Nolan GP, Giladi H, Ketzinel-Gilad M, Gross E, Galun E. Prolonged liver-specific transgene expression by a non-primate lentiviral vector. Biochemical and Biophysical Research Communications. 320: 998-1006. PMID 15240147 DOI: 10.1016/J.Bbrc.2004.06.044 |
0.551 |
|
| 2004 |
Marks KM, Braun PD, Nolan GP. A general approach for chemical labeling and rapid, spatially controlled protein inactivation. Proceedings of the National Academy of Sciences of the United States of America. 101: 9982-7. PMID 15218100 DOI: 10.1073/Pnas.0401609101 |
0.588 |
|
| 2004 |
Marks KM, Rosinov M, Nolan GP. In vivo targeting of organic calcium sensors via genetically selected peptides. Chemistry & Biology. 11: 347-56. PMID 15123264 DOI: 10.1016/J.Chembiol.2004.03.004 |
0.532 |
|
| 2004 |
Perez OD, Mitchell D, Jager GC, Nolan GP. LFA-1 signaling through p44/42 is coupled to perforin degranulation in CD56+CD8+ natural killer cells Blood. 104: 1083-1093. PMID 15113754 DOI: 10.1182/Blood-2003-08-2652 |
0.373 |
|
| 2004 |
Krutzik PO, Irish JM, Nolan GP, Perez OD. Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications Clinical Immunology. 110: 206-221. PMID 15047199 DOI: 10.1016/J.Clim.2003.11.009 |
0.78 |
|
| 2004 |
Perez OD, Krutzik PO, Nolan GP. Flow cytometric analysis of kinase signaling cascades. Methods in Molecular Biology (Clifton, N.J.). 263: 67-94. PMID 14976361 DOI: 10.1385/1-59259-773-4:067 |
0.747 |
|
| 2004 |
Wolkowicz R, Nolan GP, Curran MA. Lentiviral vectors for the delivery of DNA into mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 246: 391-411. PMID 14970606 DOI: 10.1385/1-59259-650-9:391 |
0.584 |
|
| 2004 |
Sachs K, Perez OD, Pe'er D, Nolan GP, Gifford DK, Jaakkola TS, Lauffenburger DA. Analysis of signaling pathways in human T-cells using Bayesian network modeling of single cell data Proceedings - 2004 Ieee Computational Systems Bioinformatics Conference, Csb 2004. 644. |
0.312 |
|
| 2003 |
Tarner IH, Slavin AJ, McBride J, Levicnik A, Smith R, Nolan GP, Contag CH, Fathman CG. Treatment of autoimmune disease by adoptive cellular gene therapy. Annals of the New York Academy of Sciences. 998: 512-9. PMID 14592922 DOI: 10.1196/Annals.1254.067 |
0.373 |
|
| 2003 |
Perez OD, Mitchell D, Jager GC, South S, Murriel C, McBride J, Herzenberg LA, Kinoshita S, Nolan GP. Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1 Nature Immunology. 4: 1083-1092. PMID 14528303 DOI: 10.1038/Ni984 |
0.405 |
|
| 2003 |
Krutzik PO, Nolan GP. Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 55: 61-70. PMID 14505311 DOI: 10.1002/Cyto.A.10072 |
0.741 |
|
| 2003 |
Smith R, Tarner IH, Hollenhorst M, Lin C, Levicnik AU, Fathman CG, Nolan GP. Localized expression of an anti-TNF single-chain antibody prevents development of collagen-induced arthritis. Gene Therapy. 10: 1248-57. PMID 12858190 DOI: 10.1038/Sj.Gt.3301980 |
0.321 |
|
| 2003 |
Scappaticci FA, Contreras A, Boswell CA, Lewis JS, Nolan G. Polyclonal antibodies to xenogeneic endothelial cells induce apoptosis and block support of tumor growth in mice. Vaccine. 21: 2667-77. PMID 12744904 DOI: 10.1016/S0264-410X(02)00693-X |
0.33 |
|
| 2003 |
Wolkowicz R, Nolan GP. Retroviral technology--applications for expressed peptide libraries. Frontiers in Bioscience : a Journal and Virtual Library. 8: d603-19. PMID 12700115 DOI: 10.2741/952 |
0.336 |
|
| 2002 |
Price MA, Case SS, Carbonaro DA, Yu XJ, Petersen D, Sabo KM, Curran MA, Engel BC, Margarian H, Abkowitz JL, Nolan GP, Kohn DB, Crooks GM. Expression from second-generation feline immunodeficiency virus vectors is impaired in human hematopoietic cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 645-52. PMID 12409263 DOI: 10.1016/S1525-0016(02)90725-2 |
0.598 |
|
| 2002 |
Curran MA, Ochoa MS, Molano RD, Pileggi A, Inverardi L, Kenyon NS, Nolan GP, Ricordi C, Fenjves ES. Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1. Transplantation. 74: 299-306. PMID 12177606 DOI: 10.1097/00007890-200208150-00003 |
0.55 |
|
| 2002 |
Fletcher BS, Dragstedt C, Notterpek L, Nolan GP. Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression. Leukemia. 16: 1507-18. PMID 12145692 DOI: 10.1038/Sj.Leu.2402557 |
0.34 |
|
| 2002 |
Curran MA, Nolan GP. Recombinant feline immunodeficiency virus vectors. Preparation and use. Methods in Molecular Medicine. 69: 335-50. PMID 11987787 DOI: 10.1385/1-59259-141-8:335 |
0.501 |
|
| 2002 |
Curran MA, Nolan GP. Nonprimate lentiviral vectors. Current Topics in Microbiology and Immunology. 261: 75-105. PMID 11892254 DOI: 10.1007/978-3-642-56114-6_4 |
0.576 |
|
| 2002 |
Perez OD, Nolan GP, Magda D, Miller RA, Herzenberg LA. Motexafin gadolinium (Gd-Tex) selectively induces apoptosis in HIV-1 infected CD4+ T helper cells Proceedings of the National Academy of Sciences of the United States of America. 99: 2270-2274. PMID 11854523 DOI: 10.1073/Pnas.261711499 |
0.306 |
|
| 2002 |
Perez OD, Kinoshita S, Hitoshi Y, Payan DG, Kitamura T, Nolan GP, Lorens JB. Activation of the PKB/AKT pathway by ICAM-2 Immunity. 16: 51-65. PMID 11825565 DOI: 10.1016/S1074-7613(02)00266-2 |
0.388 |
|
| 2002 |
Perez OD, Nolan GP. Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry Nature Biotechnology. 20: 155-162. PMID 11821861 DOI: 10.1038/Nbt0202-155 |
0.456 |
|
| 2001 |
Swift S, Lorens J, Achacoso P, Nolan GP. Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 10.17C. PMID 18432682 DOI: 10.1002/0471142735.Im1017Cs31 |
0.381 |
|
| 2001 |
Scappaticci FA, Contreras A, Smith R, Bonhoure L, Lum B, Cao Y, Engleman EG, Nolan GP. Statin-AE: A novel angiostatin-endostatin fusion protein with enhanced antiangiogenic and antitumor activity Angiogenesis. 4: 263-268. PMID 12197471 DOI: 10.1023/A:1016067717433 |
0.326 |
|
| 2001 |
Berquin IM, Dziubinski ML, Nolan GP, Ethier SP. A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin Oncogene. 20: 4019-4028. PMID 11494130 DOI: 10.1038/Sj.Onc.1204537 |
0.37 |
|
| 2001 |
Staal FJ, Meeldijk J, Moerer P, Jay P, van de Weerdt BC, Vainio S, Nolan GP, Clevers H. Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription. European Journal of Immunology. 31: 285-93. PMID 11265645 DOI: 10.1002/1521-4141(200101)31:1<285::Aid-Immu285>3.0.Co;2-D |
0.387 |
|
| 2001 |
Scappaticci FA, Smith R, Pathak A, Schloss D, Lum B, Cao Y, Johnson F, Engleman EG, Nolan GP. Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice Molecular Therapy. 3: 186-196. PMID 11237675 DOI: 10.1006/Mthe.2000.0243 |
0.312 |
|
| 2001 |
Orentas RJ, Roskopf SJ, Nolan GP, Nishimura MI. Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide Clinical Immunology. 98: 220-228. PMID 11161978 DOI: 10.1006/Clim.2000.4977 |
0.344 |
|
| 2001 |
Xu X, Leo C, Jang Y, Chan E, Padilla D, Huang BCB, Lin T, Gururaja T, Hitoshi Y, Lorens JB, Anderson DC, Sikic B, Luo Y, Payan DG, Nolan GP. Dominant effector genetics in mammalian cells Nature Genetics. 27: 23-29. PMID 11137994 DOI: 10.1038/83717 |
0.374 |
|
| 2000 |
Lorens JB, Bennett MK, Pearsall DM, Throndset WR, Rossi AB, Armstrong RJ, Fox BP, Chan EH, Luo Y, Masuda E, Ferrick DA, Anderson DC, Payan DG, Nolan GP. Retroviral delivery of peptide modulators of cellular functions. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 438-47. PMID 10933965 DOI: 10.1006/Mthe.2000.0063 |
0.401 |
|
| 2000 |
Curran MA, Kaiser SM, Achacoso PL, Nolan GP. Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 31-8. PMID 10933909 DOI: 10.1006/Mthe.1999.0007 |
0.596 |
|
| 2000 |
Costa GL, Benson JM, Seroogy CM, Achacoso P, Fathman CG, Nolan GP. Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 164: 3581-90. PMID 10725713 DOI: 10.4049/Jimmunol.164.7.3581 |
0.38 |
|
| 1999 |
Foo SY, Nolan GP. NF-κB to the rescue: RELs, apoptosis and cellular transformation Trends in Genetics. 15: 229-235. PMID 10354583 DOI: 10.1016/S0168-9525(99)01719-9 |
0.321 |
|
| 1999 |
Vaziri H, Squire JA, Pandita TK, Bradley G, Kuba RM, Zhang H, Gulyas S, Hill RP, Nolan GP, Benchimol S. Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts Molecular and Cellular Biology. 19: 2373-2379. PMID 10022923 DOI: 10.1128/Mcb.19.3.2373 |
0.315 |
|
| 1999 |
Yang S, Delgado R, King SR, Woffendin C, Barker CS, Yang ZY, Xu L, Nolan GP, Nabel GJ. Generation of retroviral vector for clinical studies using transient transfection Human Gene Therapy. 10: 123-132. PMID 10022537 DOI: 10.1089/10430349950019255 |
0.35 |
|
| 1999 |
Park ST, Nolan GP, Sun XH. Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells Journal of Experimental Medicine. 189: 501-508. PMID 9927512 DOI: 10.1084/Jem.189.3.501 |
0.355 |
|
| 1999 |
Dal Canto RA, Shaw MK, Nolan GP, Steinman L, Fathman CG. Local delivery of TNF by retrovirus-transduced T lymphocytes exacerbates experimental autoimmune encephalomyelitis. Clinical Immunology (Orlando, Fla.). 90: 10-4. PMID 9884347 DOI: 10.1006/Clim.1998.4653 |
0.307 |
|
| 1998 |
Hitoshi Y, Lorens J, Kitada SI, Fisher J, LaBarge M, Ring HZ, Francke U, Reed JC, Kinoshita S, Nolan GP. Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. Immunity. 8: 461-71. PMID 9586636 DOI: 10.1016/S1074-7613(00)80551-8 |
0.386 |
|
| 1997 |
Heemskerk MH, Blom B, Nolan G, Stegmann AP, Bakker AQ, Weijer K, Res PC, Spits H. Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. The Journal of Experimental Medicine. 186: 1597-602. PMID 9348318 DOI: 10.1084/Jem.186.9.1597 |
0.411 |
|
| 1997 |
Shaw MK, Lorens JB, Dhawan A, DalCanto R, Tse HY, Tran AB, Bonpane C, Eswaran SL, Brocke S, Sarvetnick N, Steinman L, Nolan GP, Fathman CG. Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 185: 1711-4. PMID 9151908 DOI: 10.1084/Jem.185.9.1711 |
0.311 |
|
| 1997 |
Kinoshita S, Su L, Amano M, Timmerman LA, Kaneshima H, Nolan GP. The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells Immunity. 6: 235-244. PMID 9075924 DOI: 10.1016/S1074-7613(00)80326-X |
0.309 |
|
| 1996 |
Choate KA, Kinsella TM, Williams ML, Nolan GP, Khavari PA. Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. Human Gene Therapy. 7: 2247-53. PMID 8953315 DOI: 10.1089/Hum.1996.7.18-2247 |
0.782 |
|
| 1996 |
Lorincz M, Roederer M, Diwu Z, Herzenberg LA, Nolan GP. Enzyme-generated intracellular fluorescence for single-cell resporter gene analysis utilizing Escherichia coli β-glucuronidase Cytometry. 24: 321-329. PMID 8866216 DOI: 10.1002/(Sici)1097-0320(19960801)24:4<321::Aid-Cyto3>3.0.Co;2-I |
0.319 |
|
| 1996 |
Kinsella TM, Nolan GP. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Human Gene Therapy. 7: 1405-13. PMID 8844199 DOI: 10.1089/Hum.1996.7.12-1405 |
0.778 |
|
| 1996 |
Anderson MT, Tjioe IM, Lorincz MC, Parks DR, Herzenberg LA, Nolan GP. Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins Proceedings of the National Academy of Sciences of the United States of America. 93: 8508-8511. PMID 8710900 DOI: 10.1073/Pnas.93.16.8508 |
0.352 |
|
| 1996 |
Onishi M, Mui ALF, Morikawa Y, Cho L, Kinoshita S, Nolan GP, Gorman DM, Miyajima A, Kitamura T. Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer Blood. 88: 1399-1406. PMID 8695859 DOI: 10.1182/Blood.V88.4.1399.Bloodjournal8841399 |
0.377 |
|
| 1996 |
Hofmann A, Nolan GP, Blau HM. Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette Proceedings of the National Academy of Sciences of the United States of America. 93: 5185-5190. PMID 8643550 DOI: 10.1073/Pnas.93.11.5185 |
0.357 |
|
| 1995 |
Kitamura T, Onishi M, Kinoshita S, Shibuya A, Miyajima A, Nolan GP. Efficient screening of retroviral cDNA expression libraries. Proceedings of the National Academy of Sciences of the United States of America. 92: 9146-50. PMID 7568090 DOI: 10.1073/Pnas.92.20.9146 |
0.341 |
|
| 1994 |
Northrop JP, Ho SN, Chen L, Thomas DJ, Timmerman LA, Nolan GP, Admon A, Crabtree GR. NF-AT components define a family of transcription factors targeted in T-cell activation. Nature. 369: 497-502. PMID 8202141 DOI: 10.1038/369497A0 |
0.327 |
|
| 1994 |
Grandison L, Nolan GP, Pfaff DW. Activation of the transcription factor NF-KB in GH3 pituitary cells. Molecular and Cellular Endocrinology. 106: 9-15. PMID 7895918 DOI: 10.1016/0303-7207(94)90180-5 |
0.305 |
|
| 1992 |
Nolan GP, Baltimore D. The inhibitory ankyrin and activator Rel proteins. Current Opinion in Genetics & Development. 2: 211-20. PMID 1386268 DOI: 10.1016/S0959-437X(05)80276-X |
0.308 |
|
| 1991 |
Kerr WG, Nolan GP, Johnsen JB, Herzenberg LA. In situ detection of stage-specific genes and enhancers in B cell differentiation via gene-search retroviruses. Advances in Experimental Medicine and Biology. 292: 187-200. PMID 1950769 DOI: 10.1007/978-1-4684-5943-2_21 |
0.332 |
|
| 1991 |
Fiering SN, Roederer M, Nolan GP, Micklem DR, Parks DR, Herzenberg LA. Improved FACS-Gal: Flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs Cytometry. 12: 291-301. PMID 1905992 DOI: 10.1002/Cyto.990120402 |
0.338 |
|
| 1991 |
Krasnow MA, Cumberledge S, Manning G, Herzenberg LA, Nolan GP. Whole animal cell sorting of Drosophila embryos. Science (New York, N.Y.). 251: 81-5. PMID 1898782 DOI: 10.1126/Science.1898782 |
0.405 |
|
| 1990 |
Yancopoulos GD, Nolan GP, Pollock R, Prockop S, Li SC, Herzenberg LA, Alt FW. A novel fluorescence-based system for assaying and separating live cells according to VDJ recombinase activity. Molecular and Cellular Biology. 10: 1697-704. PMID 2320007 DOI: 10.1128/mcb.10.4.1697-1704.1990 |
0.375 |
|
| 1990 |
Fiering S, Northrop JP, Nolan GP, Mattila PS, Crabtree GR, Herzenberg LA. Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. Genes & Development. 4: 1823-34. PMID 2123468 DOI: 10.1101/Gad.4.10.1823 |
0.353 |
|
| 1988 |
Nolan GP, Fiering S, Nicolas JF, Herzenberg LA. Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ. Proceedings of the National Academy of Sciences of the United States of America. 85: 2603-7. PMID 3128790 DOI: 10.1073/Pnas.85.8.2603 |
0.389 |
|
| 1987 |
Nakauchi H, Tagawa M, Nolan GP, Herzenberg LA. Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. Nucleic Acids Research. 15: 4337-47. PMID 3495785 DOI: 10.1093/Nar/15.10.4337 |
0.489 |
|
| 1986 |
Tagawa M, Nakauchi H, Herzenberg LA, Nolan GP. Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation. Proceedings of the National Academy of Sciences of the United States of America. 83: 3422-6. PMID 3085089 DOI: 10.1073/Pnas.83.10.3422 |
0.443 |
|
| 1985 |
Nakauchi H, Nolan GP, Hsu C, Huang HS, Kavathas P, Herzenberg LA. Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. Proceedings of the National Academy of Sciences of the United States of America. 82: 5126-30. PMID 3927298 DOI: 10.1073/Pnas.82.15.5126 |
0.431 |
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