| Year |
Citation |
Score |
| 2023 |
Chen YC, Yang X, Wang N, Sampson NS. Uncovering the Roles of in Redox and Bioenergetic Homeostasis: Implications for Antitubercular Therapy. Biorxiv : the Preprint Server For Biology. PMID 37873194 DOI: 10.1101/2023.10.02.560593 |
0.489 |
|
| 2023 |
Werman JM, Chen YC, Yuan T, Yang X, Sampson NS. A Chemoproteomic Approach to Elucidate the Mechanism of Action of 6-Azasteroids with Unique Activity in Mycobacteria. Acs Infectious Diseases. 9: 1993-2004. PMID 37774412 DOI: 10.1021/acsinfecdis.3c00296 |
0.673 |
|
| 2022 |
Yang X, Wipperman MF, Nachman S, Sampson NS. Exploring the value of Mycobacterium tuberculosis modified lipoprotein as a potential biomarker for TB detection in children. Bmc Infectious Diseases. 22: 158. PMID 35177035 DOI: 10.1186/s12879-022-07140-9 |
0.722 |
|
| 2021 |
Rosa TLSA, Marques MAM, DeBoard Z, Hutchins K, Silva CAA, Montague CR, Yuan T, Amaral JJ, Atella GC, Rosa PS, Mattos KA, VanderVen BC, Lahiri R, Sampson NS, Brennan PJ, et al. Corrigendum: Reductive Power Generated by Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis. Frontiers in Cellular and Infection Microbiology. 11: 765326. PMID 34650934 DOI: 10.3389/fcimb.2021.765326 |
0.565 |
|
| 2021 |
Rosa TLSA, Marques MAM, DeBoard Z, Hutchins K, Silva CAA, Montague CR, Yuan T, Amaral JJ, Atella GC, Rosa PS, Mattos KA, VanderVen BC, Lahiri R, Sampson NS, Brennan PJ, et al. Reductive Power Generated by Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis. Frontiers in Cellular and Infection Microbiology. 11: 709972. PMID 34395315 DOI: 10.3389/fcimb.2021.709972 |
0.599 |
|
| 2021 |
Yuan T, Werman JM, Sampson NS. The pursuit of mechanism of action: uncovering drug complexity in TB drug discovery. Rsc Chemical Biology. 2: 423-440. PMID 33928253 DOI: 10.1039/d0cb00226g |
0.542 |
|
| 2021 |
Yuan T, Werman JM, Yin X, Yang M, Garcia-Diaz M, Sampson NS. Enzymatic β-Oxidation of the Cholesterol Side Chain in Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA. Acs Infectious Diseases. PMID 33826843 DOI: 10.1021/acsinfecdis.1c00069 |
0.666 |
|
| 2020 |
Boadi FO, Zhang J, Yu X, Bhatia S, Sampson NS. Alternating Ring-Opening Metathesis Polymerization Provides Easy Access to Functional and Fully Degradable Polymers. Macromolecules. 53: 5857-5868. PMID 33776145 DOI: 10.1021/Acs.Macromol.0C01051 |
0.309 |
|
| 2020 |
Bonds A, Yuan T, Werman J, Jang J, Lu R, Nesbitt NM, Garcia-Diaz M, Sampson NS. Post-translational succinylation of enoyl-CoA hydratase EchA19 slows catalytic hydration of cholesterol catabolite 3-oxo-chol-4,22-diene-24-oyl-CoA. Acs Infectious Diseases. PMID 32649175 DOI: 10.1021/Acsinfecdis.0C00329 |
0.66 |
|
| 2020 |
Cervin J, Boucher A, Youn G, Björklund P, Wallenius V, Mottram L, Sampson NS, Yrlid U. Fucose-galactose polymers inhibit cholera toxin binding to fucosylated structures and galactose-dependent intoxication of human enteroids. Acs Infectious Diseases. PMID 32134631 DOI: 10.1021/Acsinfecdis.0C00009 |
0.306 |
|
| 2020 |
Gadbery J, Round J, Yuan T, Wipperman MF, Story KT, Crowe A, Casabon I, Liu J, Yang X, Eltis LD, Sampson NS. IpdE1-IpdE2 is a heterotetrameric acyl coenzyme A dehydrogenase that is widely distributed in steroid-degrading bacteria. Biochemistry. PMID 32101684 DOI: 10.1021/Acs.Biochem.0C00005 |
0.774 |
|
| 2019 |
Yuan T, Yang M, Gehring K, Sampson NS. exploits a heterohexameric enoyl-CoA hydratase retro-aldolase complex for cholesterol catabolism. Biochemistry. PMID 31568719 DOI: 10.1021/Acs.Biochem.9B00673 |
0.671 |
|
| 2019 |
Gadbery JE, Sampson NS. A mass spectrometry-based isotope-coded mass tag method to map thiol accessibility in biological systems. Methods in Enzymology. 621: 245-260. PMID 31128782 DOI: 10.1016/Bs.Mie.2019.02.025 |
0.301 |
|
| 2019 |
Yuan T, Sampson NS. Correction to Hit Generation in TB Drug Discovery: From Genome to Granuloma. Chemical Reviews. PMID 31058490 DOI: 10.1021/Acs.Chemrev.9B00244 |
0.577 |
|
| 2019 |
Yang X, Yuan T, Ma R, Chacko K, Smith M, Deikus G, Sebra R, Kasarkskis A, van Bakel H, Franzblau SG, Sampson NS. The Mce3R stress-resistance pathway is vulnerable to small molecule targeting that improves tuberculosis drug activities. Acs Infectious Diseases. PMID 31012313 DOI: 10.1021/Acsinfecdis.9B00099 |
0.701 |
|
| 2018 |
Li G, Sampson NS. Alternating Ring-Opening Metathesis Polymerization (AROMP) of Hydrophobic and Hydrophilic Monomers Provides Oligomers with Side-Chain Sequence Control. Macromolecules. 51: 3932-3940. PMID 30524145 DOI: 10.1021/Acs.Macromol.8B00562 |
0.311 |
|
| 2018 |
Zhang J, Li G, Sampson NS. Incorporation of Large Cycloalkene Rings into Alternating Copolymers Allows Control of Glass Transition and Hydrophobicity. Acs Macro Letters. 7: 1068-1072. PMID 30271676 DOI: 10.1021/Acsmacrolett.8B00510 |
0.305 |
|
| 2018 |
Gadbery JE, Sampson NS. Use of an Isotope-Coded Mass Tag (ICMT) Method To Determine the Orientation of Cholesterol Oxidase on Model Membranes. Biochemistry. PMID 30125103 DOI: 10.1021/Acs.Biochem.8B00788 |
0.338 |
|
| 2018 |
Bonds AC, Sampson NS. More than cholesterol catabolism: regulatory vulnerabilities in Mycobacterium tuberculosis. Current Opinion in Chemical Biology. 44: 39-46. PMID 29906645 DOI: 10.1016/J.Cbpa.2018.05.012 |
0.356 |
|
| 2018 |
Wands AM, Cervin J, Huang H, Zhang Y, Youn G, Brautigam CA, Matson Dzebo M, Bjorklund P, Wallenius V, Bright DK, Bennett CS, Wittung-Stafshede P, Sampson NS, Yrlid U, Kohler JJ. Fucosylated molecules competitively interfere with cholera toxin binding to host cells. Acs Infectious Diseases. PMID 29411974 DOI: 10.1021/Acsinfecdis.7B00085 |
0.305 |
|
| 2018 |
Chen L, Li L, Sampson NS. Access to bicyclo[4.2.0]octene monomers to explore the scope of alternating ring-opening metathesis polymerization. The Journal of Organic Chemistry. PMID 29406722 DOI: 10.1021/Acs.Joc.8B00054 |
0.325 |
|
| 2018 |
Yuan T, Sampson NS. Hit Generation in TB Drug Discovery: From Genome to Granuloma. Chemical Reviews. PMID 29384369 DOI: 10.1021/Acs.Chemrev.7B00602 |
0.601 |
|
| 2017 |
Nelson RK, Ya-Ping J, Gadbery J, Abedeen D, Sampson N, Lin RZ, Frohman MA. Phospholipase D2 loss results in increased blood pressure via inhibition of the endothelial nitric oxide synthase pathway. Scientific Reports. 7: 9112. PMID 28831159 DOI: 10.1038/S41598-017-09852-4 |
0.311 |
|
| 2017 |
Lu R, Schaefer C, Nesbitt NM, Kuper J, Kisker C, Sampson NS. Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch. Acs Infectious Diseases. PMID 28786661 DOI: 10.1021/Acsinfecdis.7B00072 |
0.393 |
|
| 2017 |
Huang H, Rodolis MT, Bhatia SR, Sampson NS. Sugars require rigid multivalent displays for activation of mouse sperm acrosomal exocytosis. Biochemistry. PMID 28509550 DOI: 10.1021/Acs.Biochem.7B00166 |
0.4 |
|
| 2016 |
Rodolis MT, Huang H, Sampson NS. Glycopolymer induction of mouse sperm acrosomal exocytosis shows highly cooperative self-antagonism. Biochemical and Biophysical Research Communications. PMID 27150629 DOI: 10.1016/J.Bbrc.2016.05.003 |
0.324 |
|
| 2016 |
Parker KA, Sampson NS. Precision Synthesis of Alternating Copolymers via Ring-Opening Polymerization of 1-Substituted Cyclobutenes. Accounts of Chemical Research. PMID 26914522 DOI: 10.1021/Acs.Accounts.5B00490 |
0.345 |
|
| 2015 |
Lu R, Schmitz W, Sampson NS. α-Methyl Acyl CoA Racemase Provides Mycobacterium tuberculosis Catabolic Access to Cholesterol Esters. Biochemistry. 54: 5669-72. PMID 26348625 DOI: 10.1021/Acs.Biochem.5B00911 |
0.367 |
|
| 2015 |
Touchette MH, Bommineni GR, Delle Bovi RJ, Gadbery JE, Nicora CD, Shukla AK, Kyle JE, Metz TO, Martin DW, Sampson NS, Miller WT, Tonge PJ, Seeliger JC. Diacyltransferase Activity and Chain Length Specificity of Mycobacterium tuberculosis PapA5 in the Synthesis of Alkyl β-Diol Lipids. Biochemistry. 54: 5457-68. PMID 26271001 DOI: 10.1021/Acs.Biochem.5B00455 |
0.387 |
|
| 2015 |
Tan L, Li G, Parker KA, Sampson NS. Ru-Catalyzed Isomerization Provides Access to Alternating Copolymers via Ring-Opening Metathesis Polymerization. Macromolecules. 48: 4793-4800. PMID 26243969 DOI: 10.1021/Acs.Macromol.5B01058 |
0.304 |
|
| 2015 |
Yang M, Lu R, Guja KE, Wipperman MF, St Clair JR, Bonds AC, Garcia-Diaz M, Sampson NS. Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α2β2 Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA. Acs Infectious Diseases. 1: 110-125. PMID 26161441 DOI: 10.1021/Id500033M |
0.763 |
|
| 2015 |
Lee S, Wang W, Lee Y, Sampson NS. Cyclic acetals as cleavable linkers for affinity capture. Organic & Biomolecular Chemistry. PMID 26152933 DOI: 10.1039/C5Ob01056J |
0.477 |
|
| 2015 |
Schaefer CM, Lu R, Nesbitt NM, Schiebel J, Sampson NS, Kisker C. FadA5 a thiolase from Mycobacterium tuberculosis: a steroid-binding pocket reveals the potential for drug development against tuberculosis. Structure (London, England : 1993). 23: 21-33. PMID 25482540 DOI: 10.1016/J.Str.2014.10.010 |
0.387 |
|
| 2014 |
Tan L, Parker KA, Sampson NS. A Bicyclo[4.2.0]octene-Derived Monomer Provides Completely Linear Alternating Copolymers via Alternating Ring-Opening Metathesis Polymerization (AROMP). Macromolecules. 47: 6572-6579. PMID 25328246 DOI: 10.1021/Ma5012039 |
0.342 |
|
| 2014 |
Yang M, Guja KE, Thomas ST, Garcia-Diaz M, Sampson NS. A distinct MaoC-like enoyl-CoA hydratase architecture mediates cholesterol catabolism in Mycobacterium tuberculosis. Acs Chemical Biology. 9: 2632-45. PMID 25203216 DOI: 10.1021/Cb500232H |
0.723 |
|
| 2014 |
Wipperman MF, Sampson NS, Thomas ST. Pathogen roid rage: cholesterol utilization by Mycobacterium tuberculosis. Critical Reviews in Biochemistry and Molecular Biology. 49: 269-93. PMID 24611808 DOI: 10.3109/10409238.2014.895700 |
0.779 |
|
| 2014 |
Gao J, Sampson NS. A GMC oxidoreductase homologue is required for acetylation of glycopeptidolipid in Mycobacterium smegmatis. Biochemistry. 53: 611-3. PMID 24444367 DOI: 10.1021/Bi4015083 |
0.469 |
|
| 2014 |
Wu L, Sampson NS. Fucose, mannose, and β-N-acetylglucosamine glycopolymers initiate the mouse sperm acrosome reaction through convergent signaling pathways. Acs Chemical Biology. 9: 468-75. PMID 24252131 DOI: 10.1021/Cb400550J |
0.543 |
|
| 2013 |
Romulus J, Tan L, Weck M, Sampson NS. Alternating ROMP copolymers containing charge-transfer units. Acs Macro Letters. 2: 749-752. PMID 24159424 DOI: 10.1021/Mz4002673 |
0.3 |
|
| 2013 |
Wipperman MF, Yang M, Thomas ST, Sampson NS. Shrinking the FadE proteome of Mycobacterium tuberculosis: insights into cholesterol metabolism through identification of an α2β2 heterotetrameric acyl coenzyme A dehydrogenase family. Journal of Bacteriology. 195: 4331-41. PMID 23836861 DOI: 10.1128/Jb.00502-13 |
0.786 |
|
| 2013 |
Su CY, London E, Sampson NS. Mapping peptide thiol accessibility in membranes using a quaternary ammonium isotope-coded mass tag (ICMT). Bioconjugate Chemistry. 24: 1235-47. PMID 23725486 DOI: 10.1021/Bc400171J |
0.315 |
|
| 2013 |
Thomas ST, Sampson NS. Mycobacterium tuberculosis utilizes a unique heterotetrameric structure for dehydrogenation of the cholesterol side chain. Biochemistry. 52: 2895-904. PMID 23560677 DOI: 10.1021/Bi4002979 |
0.673 |
|
| 2013 |
Slayden RA, Jackson M, Zucker J, Ramirez MV, Dawson CC, Crew R, Sampson NS, Thomas ST, Jamshidi N, Sisk P, Caspi R, Crick DC, McNeil MR, Pavelka MS, Niederweis M, et al. Updating and curating metabolic pathways of TB. Tuberculosis (Edinburgh, Scotland). 93: 47-59. PMID 23375378 DOI: 10.1016/J.Tube.2012.11.001 |
0.63 |
|
| 2011 |
Thomas ST, VanderVen BC, Sherman DR, Russell DG, Sampson NS. Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism. The Journal of Biological Chemistry. 286: 43668-78. PMID 22045806 DOI: 10.1074/Jbc.M111.313643 |
0.676 |
|
| 2011 |
Thomas ST, Yang X, Sampson NS. Inhibition of the M. tuberculosis 3β-hydroxysteroid dehydrogenase by azasteroids. Bioorganic & Medicinal Chemistry Letters. 21: 2216-9. PMID 21439822 DOI: 10.1016/J.Bmcl.2011.03.004 |
0.731 |
|
| 2011 |
Song A, Walker SG, Parker KA, Sampson NS. Antibacterial studies of cationic polymers with alternating, random, and uniform backbones. Acs Chemical Biology. 6: 590-9. PMID 21370918 DOI: 10.1021/Cb100413W |
0.588 |
|
| 2011 |
Yang X, Gao J, Smith I, Dubnau E, Sampson NS. Cholesterol is not an essential source of nutrition for Mycobacterium tuberculosis during infection. Journal of Bacteriology. 193: 1473-6. PMID 21257778 DOI: 10.1128/Jb.01210-10 |
0.615 |
|
| 2010 |
Song A, Parker KA, Sampson NS. Cyclic alternating ring-opening metathesis polymerization (CAROMP). Rapid access to functionalized cyclic polymers. Organic Letters. 12: 3729-31. PMID 20684538 DOI: 10.1021/Ol101432M |
0.579 |
|
| 2010 |
Song A, Lee JC, Parker KA, Sampson NS. Scope of the ring-opening metathesis polymerization (ROMP) reaction of 1-substituted cyclobutenes. Journal of the American Chemical Society. 132: 10513-20. PMID 20614908 DOI: 10.1021/Ja1037098 |
0.586 |
|
| 2010 |
Nesbitt NM, Yang X, Fontán P, Kolesnikova I, Smith I, Sampson NS, Dubnau E. A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol. Infection and Immunity. 78: 275-82. PMID 19822655 DOI: 10.1128/Iai.00893-09 |
0.588 |
|
| 2009 |
Lyubimov AY, Chen L, Sampson NS, Vrielink A. A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase. Acta Crystallographica. Section D, Biological Crystallography. 65: 1222-31. PMID 19923719 DOI: 10.1107/S0907444909037421 |
0.34 |
|
| 2009 |
Kreit J, Sampson NS. Cholesterol oxidase: physiological functions. The Febs Journal. 276: 6844-56. PMID 19843168 DOI: 10.1111/J.1742-4658.2009.07378.X |
0.358 |
|
| 2009 |
Yang X, Nesbitt NM, Dubnau E, Smith I, Sampson NS. Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis. Biochemistry. 48: 3819-21. PMID 19364125 DOI: 10.1021/Bi9005418 |
0.555 |
|
| 2009 |
Baessler KA, Lee Y, Sampson NS. Beta1 integrin is an adhesion protein for sperm binding to eggs. Acs Chemical Biology. 4: 357-66. PMID 19338281 DOI: 10.1021/Cb900013D |
0.741 |
|
| 2009 |
Song A, Parker KA, Sampson NS. Synthesis of copolymers by alternating ROMP (AROMP). Journal of the American Chemical Society. 131: 3444-5. PMID 19275253 DOI: 10.1021/Ja809661K |
0.578 |
|
| 2009 |
Lee Y, Sampson NS. Polymeric ADAM protein mimics interrogate mammalian sperm-egg binding. Chembiochem : a European Journal of Chemical Biology. 10: 929-37. PMID 19229908 DOI: 10.1002/Cbic.200800791 |
0.579 |
|
| 2008 |
Chen L, Lyubimov AY, Brammer L, Vrielink A, Sampson NS. The binding and release of oxygen and hydrogen peroxide are directed by a hydrophobic tunnel in cholesterol oxidase. Biochemistry. 47: 5368-77. PMID 18410129 DOI: 10.1021/Bi800228W |
0.34 |
|
| 2007 |
Lyubimov AY, Heard K, Tang H, Sampson NS, Vrielink A. Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase. Protein Science : a Publication of the Protein Society. 16: 2647-56. PMID 18029419 DOI: 10.1110/Ps.073168207 |
0.372 |
|
| 2007 |
Yang X, Dubnau E, Smith I, Sampson NS. Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase. Biochemistry. 46: 9058-67. PMID 17630785 DOI: 10.1021/Bi700688X |
0.576 |
|
| 2007 |
Nesbitt NM, Sampson NS. Antifungal tradecraft by cholesterol oxidase. Chemistry & Biology. 14: 238-41. PMID 17379137 DOI: 10.1016/J.Chembiol.2007.03.003 |
0.315 |
|
| 2007 |
Kempf JG, Jung JY, Ragain C, Sampson NS, Loria JP. Dynamic requirements for a functional protein hinge. Journal of Molecular Biology. 368: 131-49. PMID 17336327 DOI: 10.1016/J.Jmb.2007.01.074 |
0.314 |
|
| 2006 |
Lee Y, Sampson NS. Romping the cellular landscape: linear scaffolds for molecular recognition. Current Opinion in Structural Biology. 16: 544-50. PMID 16781140 DOI: 10.1016/J.Sbi.2006.05.015 |
0.464 |
|
| 2006 |
Baessler KA, Lee Y, Roberts KS, Facompre N, Sampson NS. Multivalent fertilinbeta oligopeptides: the dependence of fertilization inhibition on length and density. Chemistry & Biology. 13: 251-9. PMID 16638530 DOI: 10.1016/J.Chembiol.2005.12.010 |
0.744 |
|
| 2006 |
Lee JC, Parker KA, Sampson NS. Amino acid-bearing ROMP polymers with a stereoregular backbone. Journal of the American Chemical Society. 128: 4578-9. PMID 16594687 DOI: 10.1021/Ja058801V |
0.338 |
|
| 2004 |
Roberts KS, Sampson NS. A facile synthetic method to prepare fluorescently labeled ROMP polymers. Organic Letters. 6: 3253-5. PMID 15355025 DOI: 10.1021/Ol048935Y |
0.713 |
|
| 2004 |
Xiang J, Jung JY, Sampson NS. Entropy effects on protein hinges: the reaction catalyzed by triosephosphate isomerase. Biochemistry. 43: 11436-45. PMID 15350130 DOI: 10.1021/Bi049208D |
0.565 |
|
| 2004 |
Kursula I, Salin M, Sun J, Norledge BV, Haapalainen AM, Sampson NS, Wierenga RK. Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase. Protein Engineering, Design & Selection : Peds. 17: 375-82. PMID 15166315 DOI: 10.1093/Protein/Gzh048 |
0.488 |
|
| 2004 |
Xiang J, Sampson NS. Library screening studies to investigate substrate specificity in the reaction catalyzed by cholesterol oxidase. Protein Engineering, Design & Selection : Peds. 17: 341-8. PMID 15136716 DOI: 10.1093/Protein/Gzh041 |
0.594 |
|
| 2004 |
Konkar S, Gupta S, Sampson NS. Fertilin beta peptidic liposomes inhibit fertilization by steric blockage. Bioorganic & Medicinal Chemistry Letters. 14: 1381-4. PMID 15006366 DOI: 10.1016/J.Bmcl.2003.09.097 |
0.76 |
|
| 2004 |
Ahn KW, Sampson NS. Cholesterol oxidase senses subtle changes in lipid bilayer structure. Biochemistry. 43: 827-36. PMID 14730988 DOI: 10.1021/Bi035697Q |
0.588 |
|
| 2003 |
Roberts KS, Konkar S, Sampson NS. Comparison of fertilinbeta-peptide-substituted polymers and liposomes as inhibitors of in vitro fertilization. Chembiochem : a European Journal of Chemical Biology. 4: 1229-31. PMID 14613117 DOI: 10.1002/Cbic.200300672 |
0.748 |
|
| 2003 |
Sampson NS, Vrielink A. Cholesterol oxidases: a study of nature's approach to protein design. Accounts of Chemical Research. 36: 713-22. PMID 12974654 DOI: 10.1021/Ar9800587 |
0.33 |
|
| 2003 |
Roberts KS, Sampson NS. Increased polymer length of oligopeptide-substituted polynorbornenes with LiCl. The Journal of Organic Chemistry. 68: 2020-3. PMID 12608828 DOI: 10.1021/Jo0265737 |
0.708 |
|
| 2003 |
Lario PI, Sampson N, Vrielink A. Sub-atomic resolution crystal structure of cholesterol oxidase: What atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox activity Journal of Molecular Biology. 326: 1635-1650. PMID 12595270 DOI: 10.1016/S0022-2836(03)00054-8 |
0.33 |
|
| 2002 |
Yin Y, Liu P, Anderson RG, Sampson NS. Construction of a catalytically inactive cholesterol oxidase mutant: investigation of the interplay between active site-residues glutamate 361 and histidine 447. Archives of Biochemistry and Biophysics. 402: 235-42. PMID 12051668 DOI: 10.1016/S0003-9861(02)00081-4 |
0.556 |
|
| 2001 |
Sampson NS. Dissection of a flavoenzyme active site: the reaction catalyzed by cholesterol oxidase. Antioxidants & Redox Signaling. 3: 839-46. PMID 11761331 DOI: 10.1089/15230860152665019 |
0.345 |
|
| 2001 |
Yin Y, Sampson NS, Vrielink A, Lario PI. The presence of a hydrogen bond between asparagine 485 and the pi system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase. Biochemistry. 40: 13779-87. PMID 11705367 DOI: 10.1021/Bi010843I |
0.551 |
|
| 2001 |
Gupta S, Sampson NS. Dimyristoylated peptides incorporated into liposomes are polyvalent fertilin beta mimics. Organic Letters. 3: 3333-5. PMID 11594827 DOI: 10.1021/Ol016573D |
0.546 |
|
| 2001 |
Xiang J, Sun J, Sampson NS. The importance of hinge sequence for loop function and catalytic activity in the reaction catalyzed by triosephosphate isomerase. Journal of Molecular Biology. 307: 1103-12. PMID 11286559 DOI: 10.1006/Jmbi.2001.4536 |
0.649 |
|
| 2000 |
Chen X, Wolfgang DE, Sampson NS. Use of the parallax-quench method to determine the position of the active-site loop of cholesterol oxidase in lipid bilayers. Biochemistry. 39: 13383-9. PMID 11063575 DOI: 10.1021/Bi001407J |
0.351 |
|
| 2000 |
Gupta S, Li H, Sampson NS. Characterization of fertilin beta-disintegrin binding specificity in sperm-egg adhesion. Bioorganic & Medicinal Chemistry. 8: 723-9. PMID 10819161 DOI: 10.1016/S0968-0896(00)00005-5 |
0.719 |
|
| 2000 |
McCann AE, Sampson NS. A C6-flavin adduct is the major product of irreversible inactivation of cholesterol oxidase by 2α,3α-cyclopropano-5α-cholestan-3β-ol Journal of the American Chemical Society. 122: 35-39. DOI: 10.1021/Ja992053Q |
0.31 |
|
| 1999 |
Sun J, Sampson NS. Understanding protein lids: kinetic analysis of active hinge mutants in triosephosphate isomerase. Biochemistry. 38: 11474-81. PMID 10471299 DOI: 10.1021/Bi990862G |
0.504 |
|
| 1999 |
Yue QK, Kass IJ, Sampson NS, Vrielink A. Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants. Biochemistry. 38: 4277-86. PMID 10194345 DOI: 10.1021/Bi982497J |
0.36 |
|
| 1999 |
Chen H, Sampson NS. Mediation of sperm-egg fusion: evidence that mouse egg alpha6beta1 integrin is the receptor for sperm fertilinbeta. Chemistry & Biology. 6: 1-10. PMID 9889149 DOI: 10.1016/S1074-5521(99)80015-5 |
0.354 |
|
| 1998 |
Chen H, Pyluck AL, Janik M, Sampson NS. Peptides corresponding to the epidermal growth factor-like domain of mouse fertilin: synthesis and biological activity. Biopolymers. 47: 299-307. PMID 10036971 DOI: 10.1002/(Sici)1097-0282(1998)47:4<299::Aid-Bip5>3.0.Co;2-X |
0.378 |
|
| 1998 |
Kass IJ, Sampson NS. Evaluation of the role of His447 in the reaction catalyzed by cholesterol oxidase. Biochemistry. 37: 17990-8000. PMID 9922167 DOI: 10.1021/Bi982115+ |
0.316 |
|
| 1998 |
Kass IJ, Sampson NS. The importance of GLU361 position in the reaction catalyzed by cholesterol oxidase. Bioorganic & Medicinal Chemistry Letters. 8: 2663-8. PMID 9873599 DOI: 10.1016/S0960-894X(98)00478-8 |
0.311 |
|
| 1998 |
Sun J, Sampson NS. Determination of the amino acid requirements for a protein hinge in triosephosphate isomerase. Protein Science : a Publication of the Protein Society. 7: 1495-505. PMID 9684881 DOI: 10.1002/Pro.5560070702 |
0.494 |
|
| 1998 |
Sampson NS, Kass IJ, Ghoshroy KB. Assessment of the role of an omega loop of cholesterol oxidase: a truncated loop mutant has altered substrate specificity. Biochemistry. 37: 5770-8. PMID 9548964 DOI: 10.1021/Bi973067G |
0.374 |
|
| 1998 |
Sampson NS, Chen X. Increased expression of Brevibacterium sterolicum cholesterol oxidase in Escherichia coli by genetic modification. Protein Expression and Purification. 12: 347-52. PMID 9535702 DOI: 10.1006/Prep.1997.0855 |
0.302 |
|
| 1997 |
Ghoshroy KB, Zhu W, Sampson NS. Investigation of membrane disruption in the reaction catalyzed by cholesterol oxidase. Biochemistry. 36: 6133-40. PMID 9166784 DOI: 10.1021/Bi962190P |
0.353 |
|
| 1997 |
Sampson NS, McCann AE. 4,5-Cyclopropanocholestan-3β-ol Substrates for Cholesterol Oxidase and Their 1H NMR Assignments Journal of Organic Chemistry. 62: 5893-5897. DOI: 10.1021/Jo9706537 |
0.317 |
|
| 1997 |
Sampson NS, Kass IJ. Isomerization, but not oxidation, is suppressed by a single point mutation, E361Q, in the reaction catalyzed by cholesterol oxidase Journal of the American Chemical Society. 119: 855-862. DOI: 10.1021/Ja962258O |
0.346 |
|
| 1997 |
Pyluck A, Yuan R, Galligan E, Primakoff P, Myles DG, Sampson NS. ECD peptides inhibit in vitro fertilization in mice Bioorganic and Medicinal Chemistry Letters. 7: 1053-1058. DOI: 10.1016/S0960-894X(97)00160-1 |
0.327 |
|
| 1995 |
Kass IJ, Sampson NS. The isomerization catalyzed by Brevibacterium sterolicum cholesterol oxidase proceeds stereospecifically with one base. Biochemical and Biophysical Research Communications. 206: 688-93. PMID 7826388 DOI: 10.1006/Bbrc.1995.1097 |
0.316 |
|
| 1992 |
Sampson NS, Knowles JR. Segmental motion in catalysis: investigation of a hydrogen bond critical for loop closure in the reaction of triosephosphate isomerase. Biochemistry. 31: 8488-94. PMID 1390633 DOI: 10.1021/Bi00151A015 |
0.539 |
|
| 1992 |
Sampson NS, Knowles JR. Segmental movement: definition of the structural requirements for loop closure in catalysis by triosephosphate isomerase. Biochemistry. 31: 8482-7. PMID 1390632 DOI: 10.1021/Bi00151A014 |
0.542 |
|
| 1991 |
Bone R, Sampson NS, Bartlett PA, Agard DA. Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. Biochemistry. 30: 2263-72. PMID 1998685 DOI: 10.1021/Bi00222A032 |
0.518 |
|
| 1991 |
Sampson NS, Bartlett PA. Peptidic phosphonylating agents as irreversible inhibitors of serine proteases and models of the tetrahedral intermediates. Biochemistry. 30: 2255-63. PMID 1998684 DOI: 10.1021/Bi00222A031 |
0.478 |
|
| 1991 |
Sampson NS, Bartlett PA. Attempted de novo design, synthesis, and evaluation of a ligand for the allosteric site of phosphofructokinase Journal of Organic Chemistry. 56: 7179-7183. DOI: 10.1021/Jo00025A044 |
0.475 |
|
| 1989 |
SAMPSON NS, BARTLETT PA. ChemInform Abstract: Synthesis of Phosphonic Acid Derivatives by Oxidative Activation of Phosphinate Esters. Cheminform. 20. DOI: 10.1002/chin.198912236 |
0.43 |
|
| 1988 |
Sampson NS, Bartlett PA. Synthesis of phosphonic acid derivatives by oxidative activation of phosphinate esters Journal of Organic Chemistry. 53: 4500-4503. DOI: 10.1021/Jo00254A015 |
0.493 |
|
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