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Yi Lu - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
metalloproteins, DNAzymes, nanomaterials
Website:
http://www.chemistry.illinois.edu/faculty/Yi_Lu.html
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325 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Dong R, Wang L, Li Z, Jiao J, Wu Y, Feng Z, Wang X, Chen M, Cui C, Lu Y, Jiang X. Stretchable, Self-Rolled, Microfluidic Electronics Enable Conformable Neural Interfaces of Brain and Vagus Neuromodulation. Acs Nano. PMID 38165231 DOI: 10.1021/acsnano.3c10028  0.506
2023 Wang JX, Vilbert AC, Cui C, Mirts EN, Williams LH, Kim W, Zhang YJ, Lu Y. Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations. Angewandte Chemie (International Ed. in English). e202314019. PMID 37926680 DOI: 10.1002/anie.202314019  0.574
2023 Liu Y, Harnden KA, Van Stappen C, Dikanov SA, Lu Y. A designed Copper Histidine-brace enzyme for oxidative depolymerization of polysaccharides as a model of lytic polysaccharide monooxygenase. Proceedings of the National Academy of Sciences of the United States of America. 120: e2308286120. PMID 37844252 DOI: 10.1073/pnas.2308286120  0.319
2023 Van Stappen C, Dai H, Jose A, Tian S, Solomon EI, Lu Y. Primary and Secondary Coordination Sphere Effects on the Structure and Function of -Nitrosylating Azurin. Journal of the American Chemical Society. PMID 37696009 DOI: 10.1021/jacs.3c07399  0.774
2023 Liu Y, Marshall NM, Yu SS, Kim W, Gao YG, Robinson H, Nilges MJ, Zhang Y, New SY, Lu Y. Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin. Inorganic Chemistry. PMID 37424080 DOI: 10.1021/acs.inorgchem.3c01365  0.48
2023 Fan H, McGhee CE, Lake RJ, Yang Z, Guo Z, Zhang XB, Lu Y. A Highly Selective Mn(II)-Specific DNAzyme and Its Application in Intracellular Sensing. Jacs Au. 3: 1615-1622. PMID 37388692 DOI: 10.1021/jacsau.3c00062  0.586
2023 Lu Y, Liang L, Lu WF, Cheng J, Yao WF, Xie YM, Wang DD, Xu FQ, Xiao ZQ, Zhang JG, Liu JW, Zhang CW, Huang DS. The prognosis of elderly patients with hepatocellular carcinoma after curative hepatectomy a multicenter competing risk analysis. Clinics and Research in Hepatology and Gastroenterology. 47: 102147. PMID 37245639 DOI: 10.1016/j.clinre.2023.102147  0.314
2023 Wu Y, Torabi SF, Lake RJ, Hong S, Yu Z, Wu P, Yang Z, Nelson K, Guo W, Pawel GT, Van Stappen J, Shao X, Mirica LM, Lu Y. Simultaneous Fe/Fe imaging shows Fe over Fe enrichment in Alzheimer's disease mouse brain. Science Advances. 9: eade7622. PMID 37075105 DOI: 10.1126/sciadv.ade7622  0.613
2022 Pawel GT, Ma Y, Wu Y, Lu Y, Peinetti AS. Binding Affinity Measurements Between DNA Aptamers and their Virus Targets Using ELONA and MST. Bio-Protocol. 12. PMID 36505027 DOI: 10.21769/BioProtoc.4548  0.473
2022 Qian RC, Zhou ZR, Wu Y, Yang Z, Guo W, Li DW, Lu Y. Combination Cancer Treatment: Using Engineered DNAzyme Molecular Machines for Dynamic Inter- and Intracellular Regulation. Angewandte Chemie (International Ed. in English). e202210935. PMID 36253586 DOI: 10.1002/anie.202210935  0.447
2022 Zhang KJ, Liang L, Diao YK, Xie YM, Wang DD, Xu FQ, Ye TW, Lu WF, Cheng J, Shen GL, Yao WF, Lu Y, Xiao ZQ, Zhang JG, Zhang CW, et al. Short- and long-term outcomes of laparoscopic versus open liver resection for large hepatocellular carcinoma: a propensity score study. Surgery Today. PMID 35986784 DOI: 10.1007/s00595-022-02576-7  0.309
2022 Van Stappen C, Deng Y, Liu Y, Heidari H, Wang JX, Zhou Y, Ledray AP, Lu Y. Designing Artificial Metalloenzymes by Tuning of the Environment beyond the Primary Coordination Sphere. Chemical Reviews. PMID 35816578 DOI: 10.1021/acs.chemrev.2c00106  0.304
2022 Yu Y, Marshall NM, Garner DK, Nilges MJ, Lu Y. Tuning reduction potentials of type 1 copper center in azurin by replacing a histidine ligand with its isostructural analogues. Journal of Inorganic Biochemistry. 234: 111863. PMID 35691263 DOI: 10.1016/j.jinorgbio.2022.111863  0.817
2022 Shen GL, Lu Y, Liang L, Lu WF, Diao YK, Xiao ZQ, Zhang KJ, Zhang JG, Zhang CW, Liu J. Impact of diabetes mellitus on the long-term prognosis of patients with hepatocellular carcinoma after hepatectomy. Expert Review of Gastroenterology & Hepatology. 1-6. PMID 35387530 DOI: 10.1080/17474124.2022.2063837  0.306
2021 McGhee CE, Yang Z, Guo W, Wu Y, Lyu M, DeLong CJ, Hong S, Ma Y, McInnis MG, O'Shea KS, Lu Y. DNAzyme-Based Lithium-Selective Imaging Reveals Higher Lithium Accumulation in Bipolar Disorder Patient-Derived Neurons. Acs Central Science. 7: 1809-1820. PMID 34841055 DOI: 10.1021/acscentsci.1c00843  0.658
2021 Peinetti AS, Lake RJ, Cong W, Cooper L, Wu Y, Ma Y, Pawel GT, Toimil-Molares ME, Trautmann C, Rong L, Mariñas B, Azzaroni O, Lu Y. Direct detection of human adenovirus or SARS-CoV-2 with ability to inform infectivity using DNA aptamer-nanopore sensors. Science Advances. 7: eabh2848. PMID 34550739 DOI: 10.1126/sciadv.abh2848  0.431
2021 Lyu M, Kong L, Yang Z, Wu Y, McGhee CE, Lu Y. PNA-Assisted DNAzymes to Cleave Double-Stranded DNA for Genetic Engineering with High Sequence Fidelity. Journal of the American Chemical Society. PMID 34156847 DOI: 10.1021/jacs.1c03129  0.667
2021 Tian S, Fan R, Albert T, Khade RL, Dai H, Harnden KA, Hosseinzadeh P, Liu J, Nilges MJ, Zhang Y, Moënne-Loccoz P, Guo Y, Lu Y. Stepwise nitrosylation of the nonheme iron site in an engineered azurin and a molecular basis for nitric oxide signaling mediated by nonheme iron proteins. Chemical Science. 12: 6569-6579. PMID 34040732 DOI: 10.1039/d1sc00364j  0.71
2021 Qian RC, Zhou ZR, Guo W, Wu Y, Yang Z, Lu Y. Cell Surface Engineering Using DNAzymes: Metal Ion Mediated Control of Cell-Cell Interactions. Journal of the American Chemical Society. PMID 33749281 DOI: 10.1021/jacs.1c00060  0.469
2020 Bai Y, Xing H, Bai Y, Tan LH, Hwang K, Li J, Lu Y, Zimmerman SC. Independent control over size, valence, and elemental composition in the synthesis of DNA-nanoparticle conjugates. Chemical Science. 11: 1564-1572. PMID 34084387 DOI: 10.1039/c9sc05656d  0.55
2020 Yu SS, Li JJ, Cui C, Tian S, Chen JJ, Yu HQ, Hou C, Nilges MJ, Lu Y. Structural Basis for a Quadratic Relationship between Electronic Absorption and Electronic Paramagnetic Resonance Parameters of Type 1 Copper Proteins. Inorganic Chemistry. PMID 32689800 DOI: 10.1021/Acs.Inorgchem.0C01065  0.81
2020 Mirts EN, Dikanov SA, Jose A, Solomon EI, Lu Y. A Binuclear Cu Center Designed in an All α-Helical Protein Scaffold. Journal of the American Chemical Society. PMID 32662996 DOI: 10.1021/Jacs.0C04226  0.541
2020 Wu Y, Yang Z, Lu Y. Photocaged functional nucleic acids for spatiotemporal imaging in biology. Current Opinion in Chemical Biology. 57: 95-104. PMID 32652498 DOI: 10.1016/J.Cbpa.2020.05.003  0.517
2020 Wang Z, Lu Y. Functional DNA directed assembly of nanomaterials for biosensing. Journal of Materials Chemistry. 19. PMID 24307758 DOI: 10.1039/B813939C  0.347
2020 Bai Y, Xing H, Bai Y, Tan LH, Hwang K, Li J, Lu Y, Zimmerman SC. Independent control over size, valence, and elemental composition in the synthesis of DNA–nanoparticle conjugates Chemical Science. 11: 1564-1572. DOI: 10.1039/C9Sc05656D  0.558
2019 Bhagi-Damodaran A, Lu Y. The Periodic Table's Impact on Bioinorganic Chemistry and Biology's Selective Use of Metal Ions. Structure and Bonding. 182: 153-173. PMID 36567794 DOI: 10.1007/430_2019_45  0.764
2019 Lu Y. DNAzyme-Mediated Genetically Encoded Sensors for Ratiometric Imaging of Metal Ions in Living Cells. Angewandte Chemie (International Ed. in English). PMID 31746514 DOI: 10.1002/Anie.201912514  0.376
2019 Lake RJ, Yang Z, Zhang J, Lu Y. DNAzymes as Activity-Based Sensors for Metal Ions: Recent Applications, Demonstrated Advantages, Current Challenges, and Future Directions. Accounts of Chemical Research. PMID 31721559 DOI: 10.1021/Acs.Accounts.9B00419  0.37
2019 Xia L, Han MJ, Zhou L, Huang A, Yang Z, Wang T, Li F, Yu L, Tian C, Zang Z, Yang QZ, Liu C, Hong W, Lu Y, Alfonta L, et al. S-Click Reaction for Isotropic Orientation of Oxidases on Electrodes to Promote Electron Transfer at Low Potentials. Angewandte Chemie (International Ed. in English). PMID 31584750 DOI: 10.1002/Anie.201909203  0.3
2019 Lin Y, Yang Z, Lake RJ, Zheng C, Lu Y. Enzyme-Mediated Endogenous and Bioorthogonal Control of a DNAzyme Fluorescent Sensor for Imaging Metal Ions in Living Cells. Angewandte Chemie (International Ed. in English). PMID 31529664 DOI: 10.1002/Anie.201910343  0.366
2019 Li L, Xing H, Zhang J, Lu Y. Functional DNA Molecules Enable Selective and Stimuli-Responsive Nanoparticles for Biomedical Applications. Accounts of Chemical Research. PMID 31411853 DOI: 10.1021/Acs.Accounts.9B00167  0.596
2019 Hwang K, Mou Q, Lake RJ, Xiong M, Holland B, Lu Y. Metal-Dependent DNAzymes for the Quantitative Detection of Metal Ions in Living Cells: Recent Progress, Current Challenges, and Latest Results on FRET Ratiometric Sensors. Inorganic Chemistry. PMID 31364355 DOI: 10.1021/Acs.Inorgchem.9B01280  0.357
2019 Satyavolu NSR, Loh KY, Tan LH, Lu Y. Discovery of and Insights into DNA "Codes" for Tunable Morphologies of Metal Nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). e1900975. PMID 31074939 DOI: 10.1002/Smll.201900975  0.78
2019 Mirts EN, Bhagi-Damodaran A, Lu Y. Understanding and Modulating Metalloenzymes with Unnatural Amino Acids, Non-Native Metal Ions, and Non-Native Metallocofactors. Accounts of Chemical Research. PMID 30912643 DOI: 10.1021/Acs.Accounts.9B00011  0.799
2019 Dikanov SA, Berry SM, Lu Y. HYSCORE Insights into the Distribution of the Unpaired Spin Density in an Engineered Cu Site in Azurin and Its His120Gly Variant. Inorganic Chemistry. PMID 30869885 DOI: 10.1021/Acs.Inorgchem.8B03604  0.781
2019 Zhang J, Lu Y. Advancing Point-of-Care Diagnostics of Metabolites Through Engineering Semisynthetic Proteins. Clinical Chemistry. PMID 30737207 DOI: 10.1373/Clinchem.2018.298836  0.31
2019 Lu Y. New transition-metal-dependent DNAzymes as efficient endonucleases and as selective metal biosensors. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 4588-96. PMID 12362396 DOI: 10.1002/1521-3765(20021018)8:20<4588::Aid-Chem4588>3.0.Co;2-Q  0.376
2019 Dong J, Zhao D, Lu Y, Sun W. Photoluminescent metal–organic frameworks and their application for sensing biomolecules Journal of Materials Chemistry. 7: 22744-22767. DOI: 10.1039/C9Ta07022B  0.341
2018 Mukherjee S, Mukherjee M, Mukherjee A, Bhagi-Damodaran A, Lu Y, Dey A. O Reduction by Biosynthetic Models of Cytochrome Oxidase: Insights into Role of Proton Transfer Residues from Perturbed Active Sites Models of CcO. Acs Catalysis. 8: 8915-8924. PMID 35693844 DOI: 10.1021/acscatal.8b02240  0.752
2018 Sabuncu S, Reed JH, Lu Y, Moënne-Loccoz P. Nitric oxide reductase activity in heme-nonheme binuclear engineered myoglobins through a one-electron reduction cycle. Journal of the American Chemical Society. PMID 30512937 DOI: 10.1021/Jacs.8B11037  0.369
2018 Yang Z, Loh KY, Chu YT, Feng R, Satyavolu NSR, Xiong M, Huynh SMN, Hwang K, Li L, Xing H, Zhang X, Chemla YR, Gruebele M, Lu Y. Optical control of metal ion probes in cells and zebrafish using highly selective DNAzymes conjugated to upconversion nanoparticles. Journal of the American Chemical Society. PMID 30427666 DOI: 10.1021/Jacs.8B09867  0.802
2018 Mirts EN, Petrik ID, Hosseinzadeh P, Nilges MJ, Lu Y. A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme. Science (New York, N.Y.). 361: 1098-1101. PMID 30213908 DOI: 10.1126/Science.Aat8474  0.335
2018 Bhagi-Damodaran A, Reed JH, Zhu Q, Shi Y, Hosseinzadeh P, Sandoval BA, Harnden KA, Wang S, Sponholtz MR, Mirts EN, Dwaraknath S, Zhang Y, Moënne-Loccoz P, Lu Y. Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase. Proceedings of the National Academy of Sciences of the United States of America. PMID 29802230 DOI: 10.1073/Pnas.1720298115  0.78
2018 Zhang J, Xing H, Lu Y. Translating molecular detections into a simple temperature test using a target-responsive smart thermometer. Chemical Science. 9: 3906-3910. PMID 29780521 DOI: 10.1039/C7Sc05325H  0.587
2018 Cepeda-Plaza M, McGhee C, Lu Y. Evidence of a General Acid/Base Catalysis Mechanism in the 8-17 DNAzyme. Biochemistry. PMID 29389111 DOI: 10.1021/Acs.Biochem.7B01096  0.616
2018 Mukherjee S, Mukherjee M, Mukherjee A, Bhagi-Damodaran A, Lu Y, Dey A. O2 Reduction by Biosynthetic Models of Cytochrome c Oxidase: Insights into Role of Proton Transfer Residues from Perturbed Active Sites Models of CcO Acs Catalysis. 8: 8915-8924. DOI: 10.1021/Acscatal.8B02240  0.766
2017 Zhao J, Gao J, Xue W, Di Z, Xing H, Lu Y, Li L. Upconversion Luminescence-Activated DNA Nanodevice for ATP Sensing in Living Cells. Journal of the American Chemical Society. PMID 29281270 DOI: 10.1021/Jacs.7B11161  0.603
2017 Wang P, Chen K, Liu Q, Wang HW, Azam M, Al-Resayes SI, Lu Y, Sun WY. Fine tuning of catalytic and sorption properties of metal-organic frameworks via in situ ligand exchange. Dalton Transactions (Cambridge, England : 2003). PMID 28813058 DOI: 10.1039/C7Dt02231J  0.333
2017 Cohen MR, Mendelman N, Radoul M, Wilson TD, Savelieff MG, Zimmermann H, Kaminker I, Feintuch A, Lu Y, Goldfarb D. Correction to Thiolate Spin Population of Type I Copper in Azurin Derived from (33)S Hyperfine Coupling. Inorganic Chemistry. PMID 28776989 DOI: 10.1021/Acs.Inorgchem.7B01753  0.702
2017 Reed JH, Shi Y, Zhu Q, Chakraborty S, Mirts EN, Petrik ID, Bhagi-Damodaran A, Ross M, Moënne-Loccoz P, Zhang Y, Lu Y. Manganese and Cobalt in the Nonheme Metal-binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-inactive Mechanism. Journal of the American Chemical Society. PMID 28768416 DOI: 10.1021/Jacs.7B05800  0.825
2017 Xiong F, Lu L, Sun TY, Wu Q, Yan D, Chen Y, Zhang X, Wei W, Lu Y, Sun WY, Li JJ, Zhao J. A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis. Nature Communications. 8: 15912. PMID 28627513 DOI: 10.1038/Ncomms15912  0.301
2017 Wu Z, Fan H, Satyavolu NSR, Wang W, Lake R, Jiang JH, Lu Y. Imaging Endogenous Metal Ions in Living Cells Using a DNAzyme-Catalytic Hairpin Assembly Probe. Angewandte Chemie (International Ed. in English). PMID 28557357 DOI: 10.1002/Anie.201703540  0.343
2017 Ramirez Cohen M, Mendelman N, Radoul M, Wilson TD, Savelieff MG, Zimmermann H, Kaminker I, Feintuch A, Lu Y, Goldfarb D. Thiolate Spin Population of Type I Copper in Azurin Derived from (33)S Hyperfine Coupling. Inorganic Chemistry. PMID 28509562 DOI: 10.1021/Acs.Inorgchem.7B00167  0.743
2017 Wang W, Satyavolu NSR, Wu Z, Zhang JR, Zhu JJ, Lu Y. Near-Infrared Photothermally Activated DNAzyme-Gold Nanoshells for Imaging Metal Ions in Living Cells. Angewandte Chemie (International Ed. in English). PMID 28471018 DOI: 10.1002/Anie.201701325  0.352
2017 Bhagi-Damodaran A, Kahle M, Shi Y, Zhang Y, Ädelroth P, Lu Y. Insights Into How Heme Reduction Potentials Modulate Enzymatic Activities of a Myoglobin-based Functional Oxidase. Angewandte Chemie (International Ed. in English). PMID 28470988 DOI: 10.1002/Anie.201701916  0.756
2017 McGhee CE, Loh KY, Lu Y. DNAzyme sensors for detection of metal ions in the environment and imaging them in living cells. Current Opinion in Biotechnology. 45: 191-201. PMID 28458112 DOI: 10.1016/J.Copbio.2017.03.002  0.796
2017 Mazumdar D, Lan T, Lu Y. "Dipstick" Colorimetric Detection of Metal Ions Based on Immobilization of DNAzyme and Gold Nanoparticles onto a Lateral Flow Device. Methods in Molecular Biology (Clifton, N.J.). 1571: 389-406. PMID 28281269 DOI: 10.1007/978-1-4939-6848-0_24  0.601
2017 Xing H, Bai Y, Bai Y, Tan LH, Tao J, Pedretti B, Vincil GA, Lu Y, Zimmerman SC. Bottom-Up Strategy To Prepare Nanoparticles with a Single DNA Strand. Journal of the American Chemical Society. PMID 28263067 DOI: 10.1021/Jacs.7B00065  0.602
2017 Bhagi-Damodaran A, Michael MA, Zhu Q, Reed J, Sandoval BA, Mirts EN, Chakraborty S, Moënne-Loccoz P, Zhang Y, Lu Y. Why copper is preferred over iron for oxygen activation and reduction in haem-copper oxidases. Nature Chemistry. 9: 257-263. PMID 28221360 DOI: 10.1038/Nchem.2643  0.788
2017 Fan H, Zhang X, Lu Y. Recent advances in DNAzyme-based gene silencing Science China-Chemistry. 60: 591-601. DOI: 10.1007/S11426-016-0472-1  0.322
2016 Bhagi-Damodaran A, Petrik I, Lu Y. Using Biosynthetic Models of Heme-Copper Oxidase and Nitric Oxide Reductase in Myoglobin to Elucidate Structural Features Responsible for Enzymatic Activities. Israel Journal of Chemistry. 56: 773-790. PMID 27994254 DOI: 10.1002/Ijch.201600033  0.78
2016 Clark KM, Tian S, van der Donk WA, Lu Y. Probing the role of the backbone carbonyl interaction with the CuA center in azurin by replacing the peptide bond with an ester linkage. Chemical Communications (Cambridge, England). PMID 27918029 DOI: 10.1039/C6Cc07274G  0.757
2016 Zhang J, Cheng F, Li J, Zhu JJ, Lu Y. Fluorescent nanoprobes for sensing and imaging of metal ions: recent advances and future perspectives. Nano Today. 11: 309-329. PMID 27818705 DOI: 10.1016/J.Nantod.2016.05.010  0.326
2016 Yu Y, Petrik I, Chacón KN, Hosseinzadeh P, Chen H, Blackburn NJ, Lu Y. Effect of Circular Permutation on the Structure and Function of Type 1 Blue Copper Center in Azurin. Protein Science : a Publication of the Protein Society. PMID 27759897 DOI: 10.1002/Pro.3071  0.353
2016 Hwang K, Hosseinzadeh P, Lu Y. Biochemical and Biophysical Understanding of Metal Ion Selectivity of DNAzymes. Inorganica Chimica Acta. 452: 12-24. PMID 27695134 DOI: 10.1016/J.Ica.2016.04.017  0.343
2016 Bhagi-Damodaran A, Hosseinzadeh P, Mirts E, Reed J, Petrik ID, Lu Y. Design of Heteronuclear Metalloenzymes. Methods in Enzymology. 580: 501-37. PMID 27586347 DOI: 10.1016/Bs.Mie.2016.05.050  0.789
2016 Bai Y, Feng X, Xing H, Xu Y, Kim BK, Baig N, Zhou T, Gewirth AA, Lu Y, Oldfield E, Zimmerman SC. A Highly Efficient Single-Chain Metal-Organic Nanoparticle Catalyst for Alkyne-Azide "Click" Reactions in Water and in Cells. Journal of the American Chemical Society. PMID 27529791 DOI: 10.1021/Jacs.6B04477  0.627
2016 Xing H, Hwang K, Lu Y. Recent Developments of Liposomes as Nanocarriers for Theranostic Applications. Theranostics. 6: 1336-52. PMID 27375783 DOI: 10.7150/Thno.15464  0.599
2016 Nastri F, Chino M, Maglio O, Bhagi-Damodaran A, Lu Y, Lombardi A. Design and engineering of artificial oxygen-activating metalloenzymes. Chemical Society Reviews. PMID 27341693 DOI: 10.1039/C5Cs00923E  0.76
2016 Tian S, Liu J, Cowley RE, Hosseinzadeh P, Marshall NM, Yu Y, Robinson H, Nilges MJ, Blackburn NJ, Solomon EI, Lu Y. Reversible S-nitrosylation in an engineered azurin. Nature Chemistry. 8: 670-7. PMID 27325093 DOI: 10.1038/Nchem.2489  0.807
2016 Xing H, Li J, Xu W, Hwang K, Wu P, Yin Q, Li Z, Cheng J, Lu Y. The Effects of Spacer Length and Composition on Aptamer-Mediated Cell-Specific Targeting with Nanoscale PEGylated Liposomal Doxorubicin. Chembiochem : a European Journal of Chemical Biology. PMID 27123758 DOI: 10.1002/Cbic.201600092  0.586
2016 Hosseinzadeh P, Tian S, Marshall NM, Hemp J, Mullen T, Nilges MJ, Gao YG, Robinson H, Stahl DA, Gennis RB, Lu Y. A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site. Journal of the American Chemical Society. PMID 27120678 DOI: 10.1021/Jacs.5B13128  0.81
2016 Matsumura H, Chakraborty S, Reed J, Lu Y, Moënne-Loccoz P. Effect of outer-sphere sidechain substitutions on the fate of the trans iron-nitrosyl dimer in heme/nonheme engineered myoglobins (FeBMbs): Insights into the mechanism of denitrifying NO reductases. Biochemistry. PMID 27003474 DOI: 10.1021/Acs.Biochem.5B01109  0.344
2016 Chauhan S, Hosseinzadeh P, Lu Y, Blackburn NJ. Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase. Biochemistry. PMID 26982589 DOI: 10.1021/Acs.Biochem.6B00061  0.306
2016 Hosseinzadeh P, Mirts EN, Pfister TD, Gao YG, Mayne C, Robinson H, Tajkhorshid E, Lu Y. Enhancing Mn(II)-binding and manganese peroxidase activity in a designed cytochrome c peroxidase through fine-tuning secondary sphere interactions. Biochemistry. PMID 26885726 DOI: 10.1021/Acs.Biochem.5B01299  0.696
2016 Xing H, Zhang CL, Ruan G, Zhang JJ, Hwang K, Lu Y. Multimodal Detection of a Small Molecule Target Using Stimuli-Responsive Liposome Triggered by Aptamer-Enzyme Conjugate. Analytical Chemistry. PMID 26750765 DOI: 10.1021/Acs.Analchem.5B04031  0.593
2016 Yu Y, Cui C, Wang J, Lu Y. Biosynthetic approach to modeling and understanding metalloproteins using unnatural amino acids Science China Chemistry. 60: 188-200. DOI: 10.1007/S11426-016-0343-2  0.606
2015 Petrik ID, Davydov R, Ross M, Zhao X, Hoffman B, Lu Y. Spectroscopic and crystallographic evidence for the role of a water-containing hydrogen bonding network in oxidase activity of an engineered myoglobin. Journal of the American Chemical Society. PMID 26716352 DOI: 10.1021/Jacs.5B12004  0.717
2015 Hosseinzadeh P, Marshall NM, Chacón KN, Yu Y, Nilges MJ, New SY, Tashkov SA, Blackburn NJ, Lu Y. Design of a single protein that spans the entire 2-V range of physiological redox potentials. Proceedings of the National Academy of Sciences of the United States of America. PMID 26631748 DOI: 10.1073/Pnas.1515897112  0.677
2015 Torabi SF, Lu Y. Identification of the Same Na(+)-Specific DNAzyme Motif from Two In Vitro Selections Under Different Conditions. Journal of Molecular Evolution. PMID 26577294 DOI: 10.1007/S00239-015-9715-7  0.57
2015 Mukherjee S, Mukherjee A, Bhagi-Damodaran A, Mukherjee M, Lu Y, Dey A. A biosynthetic model of cytochrome c oxidase as an electrocatalyst for oxygen reduction. Nature Communications. 6: 8467. PMID 26455726 DOI: 10.1038/Ncomms9467  0.755
2015 Yang Y, Zhou Q, Wang L, Liu X, Zhang W, Hu M, Dong J, Li J, Xiaoxuan L, Ouyang H, Li H, Gao F, Gong W, Lu Y, Wang J. Significant Improvement of Oxidase Activity through the Genetic Incorporation of a Redox-active Unnatural Amino Acid. Chemical Science (Royal Society of Chemistry : 2010). 6: 3881-3885. PMID 26417427 DOI: 10.1039/C5Sc01126D  0.341
2015 Gao L, Li LL, Wang X, Wu P, Cao Y, Liang B, Li X, Lin Y, Lu Y, Guo X. Graphene-DNAzyme Junctions: A Platform for Direct Metal Ion Detection with Ultrahigh Sensitivity. Chemical Science (Royal Society of Chemistry : 2010). 6: 2469-2473. PMID 26417425 DOI: 10.1039/C4Sc03612C  0.372
2015 Chakraborty S, Polen MA, Chacón KN, Wilson TD, Yu Y, Reed J, Nilges MJ, Blackburn NJ, Lu Y. Binuclear CuA Formation in Biosynthetic Models of CuA in Azurin Proceeds via a Novel Cu(Cys)2His Mononuclear Copper Intermediate. Biochemistry. PMID 26352296 DOI: 10.1021/Acs.Biochem.5B00659  0.602
2015 Bhagi-Damodaran A, Lu Y. The Q, Compound Q is Finally Deciphered. Inorganic Chemistry Frontiers. 2: 824-826. PMID 26346336 DOI: 10.1039/C5Qi00117J  0.726
2015 Bai Y, Xing H, Wu P, Feng X, Hwang K, Lee JM, Phang XY, Lu Y, Zimmerman SC. Chemical Control over Cellular Uptake of Organic Nanoparticles by Fine Tuning Surface Functional Groups. Acs Nano. PMID 26327513 DOI: 10.1021/Acsnano.5B03909  0.586
2015 Yu Y, Cui C, Liu X, Petrik ID, Wang J, Lu Y. A Designed Metalloenzyme Achieving the Catalytic Rate of a Native Enzyme. Journal of the American Chemical Society. PMID 26318313 DOI: 10.1021/Jacs.5B07119  0.602
2015 Hosseinzadeh P, Lu Y. Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics. Biochimica Et Biophysica Acta. PMID 26301482 DOI: 10.1016/J.Bbabio.2015.08.006  0.333
2015 Chakraborty S, Reed J, Sage JT, Branagan NC, Petrik ID, Miner KD, Hu MY, Zhao J, Alp EE, Lu Y. Recent Advances in Biosynthetic Modeling of Nitric Oxide Reductases and Insights Gained from Nuclear Resonance Vibrational and Other Spectroscopic Studies. Inorganic Chemistry. PMID 26274098 DOI: 10.1021/Acs.Inorgchem.5B01105  0.628
2015 Farver O, Hosseinzadeh P, Marshall NM, Wherland S, Lu Y, Pecht I. Long-Range Electron Transfer in Engineered Azurins Exhibits Marcus Inverted Region Behavior. The Journal of Physical Chemistry Letters. 6: 100-5. PMID 26263097 DOI: 10.1021/Jz5022685  0.64
2015 Song T, Tang L, Tan LH, Wang X, Satyavolu NS, Xing H, Wang Z, Li J, Liang H, Lu Y. DNA-Encoded Tuning of Geometric and Plasmonic Properties of Nanoparticles Growing from Gold Nanorod Seeds. Angewandte Chemie (International Ed. in English). 54: 8114-8. PMID 26096755 DOI: 10.1002/Anie.201500838  0.712
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2014 Miner KD, Pfister TD, Hosseinzadeh P, Karaduman N, Donald LJ, Loewen PC, Lu Y, Ivancich A. Identifying the elusive sites of tyrosyl radicals in cytochrome c peroxidase: implications for oxidation of substrates bound at a site remote from the heme. Biochemistry. 53: 3781-9. PMID 24901481 DOI: 10.1021/Bi500353P  0.759
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2009 Brown AK, Liu J, He Y, Lu Y. Biochemical characterization of a uranyl ion-specific DNAzyme. Chembiochem : a European Journal of Chemical Biology. 10: 486-92. PMID 19142882 DOI: 10.1002/Cbic.200800632  0.618
2009 Ravel B, Slimmer SC, Meng X, Wong GCL, Lu Y. EXAFS studies of catalytic DNA sensors for mercury contamination of water Radiation Physics and Chemistry. 78. DOI: 10.1016/J.Radphyschem.2009.05.024  0.302
2008 Park JU, Lee JH, Paik U, Lu Y, Rogers JA. Nanoscale patterns of oligonucleotides formed by electrohydrodynamic jet printing with applications in biosensing and nanomaterials assembly. Nano Letters. 8: 4210-6. PMID 19367962 DOI: 10.1021/Nl801832V  0.389
2008 Wang Z, Lee JH, Lu Y. Highly sensitive "turn-on" fluorescent sensor for Hg2+ in aqueous solution based on structure-switching DNA. Chemical Communications. 6005-6007. PMID 19030567 DOI: 10.1039/B812755G  0.411
2008 Lee JH, Wang Z, Liu J, Lu Y. Highly sensitive and selective colorimetric sensors for uranyl (UO2(2+)): development and comparison of labeled and label-free DNAzyme-gold nanoparticle systems. Journal of the American Chemical Society. 130: 14217-26. PMID 18837498 DOI: 10.1021/Ja803607Z  0.571
2008 Yeung N, Lu Y. One heme, diverse functions: using biosynthetic myoglobin models to gain insights into heme-copper oxidases and nitric oxide reductases. Chemistry & Biodiversity. 5: 1437-48. PMID 18729107 DOI: 10.1002/Cbdv.200890134  0.767
2008 Kim HK, Li J, Nagraj N, Lu Y. Probing metal binding in the 8-17 DNAzyme by TbIII luminescence spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 8696-703. PMID 18688837 DOI: 10.1002/Chem.200701789  0.8
2008 Shyr MH, Wernette DP, Wiltzius P, Lu Y, Braun PV. DNA and DNAzyme-mediated 2D colloidal assembly. Journal of the American Chemical Society. 130: 8234-40. PMID 18540602 DOI: 10.1021/Ja711026R  0.77
2008 Savelieff MG, Wilson TD, Elias Y, Nilges MJ, Garner DK, Lu Y. Experimental evidence for a link among cupredoxins: red, blue, and purple copper transformations in nitrous oxide reductase. Proceedings of the National Academy of Sciences of the United States of America. 105: 7919-24. PMID 18535143 DOI: 10.1073/Pnas.0711316105  0.8
2008 Dalavoy TS, Wernette DP, Gong M, Sweedler JV, Lu Y, Flachsbart BR, Shannon MA, Bohn PW, Cropek DM. Immobilization of DNAzyme catalytic beacons on PMMA for Pb2+ detection. Lab On a Chip. 8: 786-93. PMID 18432350 DOI: 10.1039/B718624J  0.792
2008 Zhang JL, Garner DK, Liang L, Chen Q, Lu Y. Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole. Chemical Communications (Cambridge, England). 1665-7. PMID 18368158 DOI: 10.1039/B718915J  0.778
2008 Xie X, Gorelsky SI, Sarangi R, Garner DK, Hwang HJ, Hodgson KO, Hedman B, Lu Y, Solomon EI. Perturbations to the geometric and electronic structure of the CuA site: factors that influence delocalization and their contributions to electron transfer. Journal of the American Chemical Society. 130: 5194-205. PMID 18348522 DOI: 10.1021/Ja7102668  0.792
2008 Sarangi R, Gorelsky SI, Basumallick L, Hwang HJ, Pratt RC, Stack TD, Lu Y, Hodgson KO, Hedman B, Solomon EI. Spectroscopic and density functional theory studies of the blue-copper site in M121SeM and C112SeC azurin: Cu-Se versus Cu-S bonding. Journal of the American Chemical Society. 130: 3866-77. PMID 18314977 DOI: 10.1021/Ja076495A  0.63
2008 Sieracki NA, Hwang HJ, Lee MK, Garner DK, Lu Y. A temperature independent pH (TIP) buffer for biomedical biophysical applications at low temperatures. Chemical Communications (Cambridge, England). 823-5. PMID 18253516 DOI: 10.1039/B714446F  0.75
2008 Yigit MV, Mazumdar D, Lu Y. MRI detection of thrombin with aptamer functionalized superparamagnetic iron oxide nanoparticles. Bioconjugate Chemistry. 19: 412-7. PMID 18173225 DOI: 10.1021/Bc7003928  0.713
2008 Wernette DP, Liu J, Bohn PW, Lu Y. Functional-DNA-based nanoscale materials and devices for sensing trace contaminants in water Mrs Bulletin. 33: 34-41. DOI: 10.1557/Mrs2008.12  0.772
2008 Bai Z, Liu G, Lu Y, Sun W. Preparation, structure, magnetic and photoluminescence properties of copper(II) and cadmium(II) frameworks with 4,4′-bipyridine-2,2′,6,6′-tetracarboxylate Inorganic Chemistry Communications. 11: 513-517. DOI: 10.1016/J.Inoche.2008.02.004  0.306
2008 Savelieff MG, Lu Y. pH dependent copper binding properties of a CuA azurin variant with both bridging cysteines replaced with serines Inorganica Chimica Acta. 361: 1087-1094. DOI: 10.1016/J.Ica.2007.08.007  0.679
2008 Lu Y, Lu X, Huang Y, Okamura T, Kong L, Sun W, Ueyama N. Syntheses, Structures and Luminescent Properties of Metal Complexes with Imidazole-Containing Polyamine Ligand Zeitschrift FüR Anorganische Und Allgemeine Chemie. 634: 708-713. DOI: 10.1002/Zaac.200700496  0.322
2008 Wang Z, Lee JH, Lu Y. Label-free colorimetric detection of lead ions with a nanomolar detection limit and tunable dynamic range by using gold nanoparticles and DNAzyme Advanced Materials. 20: 3263-3267. DOI: 10.1002/Adma.200703181  0.446
2007 Liu J, Lu Y. Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles. Chemical Communications (Cambridge, England). 4872-4. PMID 18361353 DOI: 10.1039/B712421J  0.523
2007 Denofrio LA, Russell B, Lopatto D, Lu Y. Mentoring: Linking student interests to science curricula Science. 318: 1872-1873. PMID 18096791 DOI: 10.1126/Science.1150788  0.615
2007 Kim HK, Rasnik I, Liu J, Ha T, Lu Y. Dissecting metal ion-dependent folding and catalysis of a single DNAzyme. Nature Chemical Biology. 3: 763-8. PMID 17965708 DOI: 10.1038/Nchembio.2007.45  0.62
2007 Lee JH, Wernette DP, Yigit MV, Liu J, Wang Z, Lu Y. Site-specific control of distances between gold nanoparticles using phosphorothioate anchors on DNA and a short bifunctional molecular fastener. Angewandte Chemie (International Ed. in English). 46: 9006-10. PMID 17960545 DOI: 10.1002/Anie.200702569  0.763
2007 Liu J, Lu Y. Rational design of "turn-on" allosteric DNAzyme catalytic beacons for aqueous mercury ions with ultrahigh sensitivity and selectivity. Angewandte Chemie (International Ed. in English). 46: 7587-90. PMID 17722216 DOI: 10.1002/Anie.200702006  0.495
2007 Yigit MV, Mazumdar D, Kim HK, Lee JH, Odintsov B, Lu Y. Smart "turn-on" magnetic resonance contrast agents based on aptamer-functionalized superparamagnetic iron oxide nanoparticles. Chembiochem : a European Journal of Chemical Biology. 8: 1675-8. PMID 17696177 DOI: 10.1002/Cbic.200700323  0.748
2007 Wernette DP, Mead C, Bohn PW, Lu Y. Surface immobilization of catalytic beacons based on ratiometric fluorescent DNAzyme sensors: a systematic study. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 9513-21. PMID 17676880 DOI: 10.1021/La701303K  0.792
2007 Liu J, Lu Y. A DNAzyme catalytic beacon sensor for paramagnetic Cu2+ ions in aqueous solution with high sensitivity and selectivity. Journal of the American Chemical Society. 129: 9838-9. PMID 17645334 DOI: 10.1021/Ja0717358  0.555
2007 Liu J, Lu Y. Non-base pairing DNA provides a new dimension for controlling aptamer-linked nanoparticles and sensors. Journal of the American Chemical Society. 129: 8634-43. PMID 17567134 DOI: 10.1021/Ja072075+  0.495
2007 Kim HK, Liu J, Li J, Nagraj N, Li M, Pavot CM, Lu Y. Metal-dependent global folding and activity of the 8-17 DNAzyme studied by fluorescence resonance energy transfer. Journal of the American Chemical Society. 129: 6896-902. PMID 17488081 DOI: 10.1021/Ja0712625  0.811
2007 Liu J, Lee JH, Lu Y. Quantum dot encoding of aptamer-linked nanostructures for one-pot simultaneous detection of multiple analytes. Analytical Chemistry. 79: 4120-5. PMID 17477504 DOI: 10.1021/Ac070055K  0.517
2007 Lu Y, Liu J. Smart nanomaterials inspired by biology: dynamic assembly of error-free nanomaterials in response to multiple chemical and biological stimuli. Accounts of Chemical Research. 40: 315-23. PMID 17474707 DOI: 10.1021/Ar600053G  0.452
2007 Liu J, Brown AK, Meng X, Cropek DM, Istok JD, Watson DB, Lu Y. A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity. Proceedings of the National Academy of Sciences of the United States of America. 104: 2056-61. PMID 17284609 DOI: 10.1073/Pnas.0607875104  0.513
2007 Farver O, Hwang HJ, Lu Y, Pecht I. Reorganization energy of the CuA center in purple azurin: impact of the mixed valence-to-trapped valence state transition. The Journal of Physical Chemistry. B. 111: 6690-4. PMID 17274649 DOI: 10.1021/Jp0672555  0.483
2007 Pfister TD, Mirarefi AY, Gengenbach AJ, Zhao X, Danstrom C, Conatser N, Gao YG, Robinson H, Zukoski CF, Wang AH, Lu Y. Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 12: 126-37. PMID 17021923 DOI: 10.1007/S00775-006-0171-0  0.814
2007 Lu Y, Pfister TD. Beyond Heme‐Thiolate Interactions: Roles of the Secondary Coordination Sphere in Cytochrome P450 Systems Metal Ions in Life Sciences. 3: 267-284. DOI: 10.1002/9780470028155.Ch9  0.619
2006 Liu J, Lu Y. Preparation of aptamer-linked gold nanoparticle purple aggregates for colorimetric sensing of analytes. Nature Protocols. 1: 246-52. PMID 17406240 DOI: 10.1038/Nprot.2006.38  0.5
2006 Garner DK, Vaughan MD, Hwang HJ, Savelieff MG, Berry SM, Honek JF, Lu Y. Reduction potential tuning of the blue copper center in Pseudomonas aeruginosa azurin by the axial methionine as probed by unnatural amino acids. Journal of the American Chemical Society. 128: 15608-17. PMID 17147368 DOI: 10.1021/Ja062732I  0.79
2006 Lu Y. Metalloprotein and metallo-DNA/RNAzyme design: Current approaches, success measures, and future challenges Inorganic Chemistry. 45: 9930-9940. PMID 17140190 DOI: 10.1021/Ic052007T  0.364
2006 Liu J, Mazumdar D, Lu Y. A simple and sensitive "dipstick" test in serum based on lateral flow separation of aptamer-linked nanostructures. Angewandte Chemie (International Ed. in English). 45: 7955-9. PMID 17094149 DOI: 10.1002/Anie.200603106  0.624
2006 Lu Y, Liu J. Functional DNA nanotechnology: emerging applications of DNAzymes and aptamers. Current Opinion in Biotechnology. 17: 580-8. PMID 17056247 DOI: 10.1016/J.Copbio.2006.10.004  0.484
2006 Liu J, Lu Y. Design of asymmetric DNAzymes for dynamic control of nanoparticle aggregation states in response to chemical stimuli. Organic & Biomolecular Chemistry. 4: 3435-41. PMID 17036137 DOI: 10.1039/B605799C  0.505
2006 Lu Y. Biosynthetic inorganic chemistry Angewandte Chemie - International Edition. 45: 5588-5601. PMID 16900547 DOI: 10.1002/Anie.200600168  0.307
2006 Liu J, Lu Y. Fluorescent DNAzyme biosensors for metal ions based on catalytic molecular beacons. Methods in Molecular Biology (Clifton, N.J.). 335: 275-88. PMID 16785634 DOI: 10.1385/1-59745-069-3:275  0.532
2006 Liu J, Lu Y. Multi-fluorophore fluorescence resonance energy transfer for probing nucleic acids structure and folding. Methods in Molecular Biology (Clifton, N.J.). 335: 257-71. PMID 16785633 DOI: 10.1385/1-59745-069-3:257  0.482
2006 Zhao X, Yeung N, Russell BS, Garner DK, Lu Y. Catalytic reduction of NO to N2O by a designed heme copper center in myoglobin: implications for the role of metal ions. Journal of the American Chemical Society. 128: 6766-7. PMID 16719438 DOI: 10.1021/Ja058822P  0.823
2006 Hwang HJ, Nagraj N, Lu Y. Spectroscopic characterizations of bridging cysteine ligand variants of an engineered Cu2(Scys)2 CuA azurin. Inorganic Chemistry. 45: 102-7. PMID 16390045 DOI: 10.1021/Ic051375U  0.813
2006 Wernette DP, Swearingen CB, Cropek DM, Lu Y, Sweedler JV, Bohn PW. Incorporation of a DNAzyme into Au-coated nanocapillary array membranes with an internal standard for Pb(ii) sensing. The Analyst. 131: 41-7. PMID 16365661 DOI: 10.1039/B510071B  0.783
2006 Liu J, Lu Y. Smart Nanomaterials Responsive to Multiple Chemical Stimuli with Controllable Cooperativity Advanced Materials. 18: 1667-1671. DOI: 10.1002/Adma.200600525  0.427
2005 Wang N, Zhao X, Lu Y. Role of heme types in heme-copper oxidases: effects of replacing a heme b with a heme o mimic in an engineered heme-copper center in myoglobin. Journal of the American Chemical Society. 127: 16541-7. PMID 16305243 DOI: 10.1021/Ja052659G  0.493
2005 Liu J, Lu Y. Fast colorimetric sensing of adenosine and cocaine based on a general sensor design involving aptamers and nanoparticles. Angewandte Chemie (International Ed. in English). 45: 90-4. PMID 16292781 DOI: 10.1002/Anie.200502589  0.527
2005 Hwang HJ, Carey JR, Brower ET, Gengenbach AJ, Abramite JA, Lu Y. Blue ferrocenium azurin: an organometalloprotein with tunable redox properties. Journal of the American Chemical Society. 127: 15356-7. PMID 16262384 DOI: 10.1021/Ja054983H  0.796
2005 Liu J, Wernette DP, Lu Y. Proofreading and error removal in a nanomaterial assembly. Angewandte Chemie (International Ed. in English). 44: 7290-3. PMID 16229045 DOI: 10.1002/Anie.200501815  0.748
2005 Liu J, Lu Y. Stimuli-responsive disassembly of nanoparticle aggregates for light-up colorimetric sensing. Journal of the American Chemical Society. 127: 12677-83. PMID 16144417 DOI: 10.1021/Ja053567U  0.483
2005 Yim TJ, Liu J, Lu Y, Kane RS, Dordick JS. Highly active and stable DNAzyme-carbon nanotube hybrids. Journal of the American Chemical Society. 127: 12200-1. PMID 16131179 DOI: 10.1021/Ja0541581  0.475
2005 Nelson KE, Bruesehoff PJ, Lu Y. In vitro selection of high temperature Zn(2+)-dependent DNAzymes. Journal of Molecular Evolution. 61: 216-25. PMID 16096680 DOI: 10.1007/S00239-004-0374-3  0.801
2005 Shaikh KA, Ryu KS, Goluch ED, Nam JM, Liu J, Thaxton CS, Chiesl TN, Barron AE, Lu Y, Mirkin CA, Liu C. A modular microfluidic architecture for integrated biochemical analysis. Proceedings of the National Academy of Sciences of the United States of America. 102: 9745-50. PMID 15985549 DOI: 10.1073/Pnas.0504082102  0.567
2005 Chang IH, Tulock JJ, Liu J, Kim WS, Cannon DM, Lu Y, Bohn PW, Sweedler JV, Cropek DM. Miniaturized lead sensor based on lead-specific DNAzyme in a nanocapillary interconnected microfluidic device. Environmental Science & Technology. 39: 3756-61. PMID 15952382 DOI: 10.1021/Es040505F  0.486
2005 Hwang HJ, Berry SM, Nilges MJ, Lu Y. Axial methionine has much less influence on reduction potentials in a CuA center than in a blue copper center. Journal of the American Chemical Society. 127: 7274-5. PMID 15898751 DOI: 10.1021/Ja0501114  0.811
2005 Chen J, Wang X, Zhu Y, Lin J, Yang X, Li Y, Lu Y, Guo Z. An asymmetric dizinc phosphodiesterase model with phenolate and carboxylate bridges. Inorganic Chemistry. 44: 3422-30. PMID 15877422 DOI: 10.1021/Ic048654M  0.317
2005 Zhao X, Nilges MJ, Lu Y. Redox-dependent structural changes in an engineered heme-copper center in myoglobin: Insights into chloride binding to CUB in heme copper oxidases Biochemistry. 44: 6559-6564. PMID 15850389 DOI: 10.1021/Bi047465C  0.377
2005 Seifert JL, Pfister TD, Nocek JM, Lu Y, Hoffman BM. Hopping in the electron-transfer photocycle of the 1:1 complex of Zn-cytochrome c peroxidase with cytochrome c. Journal of the American Chemical Society. 127: 5750-1. PMID 15839648 DOI: 10.1021/Ja042459P  0.66
2005 Lu Y. Design and engineering of metalloproteins containing unnatural amino acids or non-native metal-containing cofactors. Current Opinion in Chemical Biology. 9: 118-26. PMID 15811795 DOI: 10.1016/J.Cbpa.2005.02.017  0.338
2005 Zhao X, Yeung N, Wang Z, Guo Z, Lu Y. Effects of metal ions in the CuB center on the redox properties of heme in heme-copper oxidases: spectroelectrochemical studies of an engineered heme-copper center in myoglobin. Biochemistry. 44: 1210-4. PMID 15667214 DOI: 10.1021/Bi0479151  0.773
2005 Pfister TD, Ohki T, Ueno T, Hara I, Adachi S, Makino Y, Ueyama N, Lu Y, Watanabe Y. Monooxygenation of an aromatic ring by F43W/H64D/V68I myoglobin mutant and hydrogen peroxide. Myoglobin mutants as a model for P450 hydroxylation chemistry. The Journal of Biological Chemistry. 280: 12858-66. PMID 15664991 DOI: 10.1074/Jbc.M410853200  0.666
2005 Swearingen CB, Wernette DP, Cropek DM, Lu Y, Sweedler JV, Bohn PW. Immobilization of a catalytic DNA molecular beacon on Au for Pb(II) detection. Analytical Chemistry. 77: 442-8. PMID 15649039 DOI: 10.1021/Ac0401016  0.791
2004 Liu J, Lu Y. Colorimetric biosensors based on DNAzyme-assembled gold nanoparticles. Journal of Fluorescence. 14: 343-54. PMID 15617377 DOI: 10.1023/B:Jofl.0000031816.06134.D3  0.498
2004 Liu J, Lu Y. Accelerated color change of gold nanoparticles assembled by DNAzymes for simple and fast colorimetric Pb2+ detection. Journal of the American Chemical Society. 126: 12298-305. PMID 15453763 DOI: 10.1021/Ja046628H  0.512
2004 Carey JR, Ma SK, Pfister TD, Garner DK, Kim HK, Abramite JA, Wang Z, Guo Z, Lu Y. A site-selective dual anchoring strategy for artificial metalloprotein design. Journal of the American Chemical Society. 126: 10812-3. PMID 15339144 DOI: 10.1021/Ja046908X  0.798
2004 Hwang HJ, Lu Y. pH-dependent transition between delocalized and trapped valence states of a CuA center and its possible role in proton-coupled electron transfer. Proceedings of the National Academy of Sciences of the United States of America. 101: 12842-7. PMID 15326290 DOI: 10.1073/Pnas.0403473101  0.54
2004 Ralle M, Berry SM, Nilges MJ, Gieselman MD, van der Donk WA, Lu Y, Blackburn NJ. The selenocysteine-substituted blue copper center: spectroscopic investigations of Cys112SeCys Pseudomonas aeruginosa azurin. Journal of the American Chemical Society. 126: 7244-56. PMID 15186162 DOI: 10.1021/Ja031821H  0.789
2004 Hwang HJ, Lu Y. Spectroscopic evidence for interactions between hexacyanoiron(II/III) and an engineered purple CuA azurin. Journal of Inorganic Biochemistry. 98: 797-802. PMID 15134925 DOI: 10.1016/J.Jinorgbio.2004.01.001  0.574
2004 Hwang HJ, Ang M, Lu Y. Determination of reduction potential of an engineered Cu(A) azurin by cyclic voltammetry and spectrochemical titrations. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 489-94. PMID 15127249 DOI: 10.1007/S00775-004-0547-Y  0.498
2004 Liu J, Lu Y. Adenosine-dependent assembly of aptazyme-functionalized gold nanoparticles and its application as a colorimetric biosensor. Analytical Chemistry. 76: 1627-32. PMID 15018560 DOI: 10.1021/Ac0351769  0.5
2004 Liu J, Lu Y. Optimization of a Pb2+-Directed Gold Nanoparticle/DNAzyme Assembly and Its Application as a Colorimetric Biosensor for Pb2+ Chemistry of Materials. 16: 3231-3238. DOI: 10.1021/Cm049453J  0.491
2003 Liu J, Lu Y. Improving fluorescent DNAzyme biosensors by combining inter- and intramolecular quenchers. Analytical Chemistry. 75: 6666-72. PMID 14640743 DOI: 10.1021/Ac034924R  0.504
2003 Feng M, Tachikawa H, Wang X, Pfister TD, Gengenbach AJ, Lu Y. Resonance Raman spectroscopy of cytochrome c peroxidase variants that mimic manganese peroxidase. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 8: 699-706. PMID 14505074 DOI: 10.1007/S00775-003-0460-9  0.79
2003 Berry SM, Ralle M, Low DW, Blackburn NJ, Lu Y. Probing the role of axial methionine in the blue copper center of azurin with unnatural amino acids. Journal of the American Chemical Society. 125: 8760-8. PMID 12862470 DOI: 10.1021/Ja029699U  0.786
2003 Brown AK, Li J, Pavot CM-, Lu Y. A Lead-Dependent DNAzyme with a Two-Step Mechanism† Biochemistry. 42: 7152-7161. PMID 12795611 DOI: 10.1021/Bi027332W  0.31
2003 Liu J, Lu Y. A colorimetric lead biosensor using DNAzyme-directed assembly of gold nanoparticles. Journal of the American Chemical Society. 125: 6642-3. PMID 12769568 DOI: 10.1021/Ja034775U  0.485
2003 Lu Y, Liu J, Li J, Bruesehoff PJ, Pavot CM, Brown AK. New highly sensitive and selective catalytic DNA biosensors for metal ions. Biosensors & Bioelectronics. 18: 529-40. PMID 12706559 DOI: 10.1016/S0956-5663(03)00013-7  0.801
2003 Sigman JA, Kim HK, Zhao X, Carey JR, Lu Y. The role of copper and protons in heme-copper oxidases: kinetic study of an engineered heme-copper center in myoglobin. Proceedings of the National Academy of Sciences of the United States of America. 100: 3629-34. PMID 12655052 DOI: 10.1073/pnas.0737308100  0.809
2003 Perera R, Sono M, Sigman JA, Pfister TD, Lu Y, Dawson JH. Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction. Proceedings of the National Academy of Sciences of the United States of America. 100: 3641-6. PMID 12655049 DOI: 10.1073/Pnas.0737142100  0.802
2003 Liu J, Lu Y. FRET study of a trifluorophore-labeled DNAzyme. Journal of the American Chemical Society. 124: 15208-16. PMID 12487596 DOI: 10.1021/Ja027647Z  0.514
2003 Lu Y, Sigman JA, Kim HK, Zhao X, Carey JR. The role of copper and protons in heme-copper oxidases: Kinetic study of an engineered heme-copper center in myoglobin Journal of Inorganic Biochemistry. 96: 183. DOI: 10.1016/S0162-0134(03)80696-7  0.782
2003 Lu Y, Brown AK, Liu J, Li J, Bruesehoff PJ. Biochemical and biophysical study of transition metal ion-dependent DNAzymes Journal of Inorganic Biochemistry. 96: 182. DOI: 10.1016/S0162-0134(03)80695-5  0.788
2003 Lu Y, Berry SM, Gieselman MD, Ralle M, Low DW, van der Donk WA, Blackburn NJ. Introducing unnatural amino acids into protein metal-binding sites and its role in metalloprotein design and engineering Journal of Inorganic Biochemistry. 96: 181. DOI: 10.1016/S0162-0134(03)80694-3  0.784
2003 Lu Y, Liu J, Bruesehoff PJ, Brown AK, Nelson KE, Kim H, Wernette DP. New fluorescent and colorimetric DNAzyme biosensors for metal ions Journal of Inorganic Biochemistry. 96: 30. DOI: 10.1016/S0162-0134(03)80452-X  0.781
2002 Holloway GA, Pavot C, Scaringe SA, Lu Y, Rauchfuss TB. An organometallic route to oligonucleotides containing phosphoroselenoate. Chembiochem : a European Journal of Chemical Biology. 3: 1061-5. PMID 12404630 DOI: 10.1002/1439-7633(20021104)3:11<1061::Aid-Cbic1061>3.0.Co;2-9  0.324
2002 Epel B, Slutter CS, Neese F, Kroneck PM, Zumft WG, Pecht I, Farver O, Lu Y, Goldfarb D. Electron-mediating Cu(A) centers in proteins: a comparative high field (1)H ENDOR study. Journal of the American Chemical Society. 124: 8152-62. PMID 12095361 DOI: 10.1021/Ja012514J  0.369
2002 Lu Y, Sousa A, Franco R, Mangravita A, Ferreira GC, Moura I, Shelnutt JA. Binding of protoporphyrin IX and metal derivatives to the active site of wild-type mouse ferrochelatase at low porphyrin-to-protein ratios. Biochemistry. 41: 8253-62. PMID 12081474 DOI: 10.1021/Bi025569M  0.302
2002 Bruesehoff PJ, Li J, Augustine AJ, Lu Y. Improving metal ion specificity during in vitro selection of catalytic DNA. Combinatorial Chemistry & High Throughput Screening. 5: 327-35. PMID 12052183 DOI: 10.2174/1386207023330264  0.8
2002 Lukoyanov D, Berry SM, Lu Y, Antholine WE, Scholes CP. Role of the coordinating histidine in altering the mixed valency of Cu(A): an electron nuclear double resonance-electron paramagnetic resonance investigation. Biophysical Journal. 82: 2758-66. PMID 11964261 DOI: 10.1016/S0006-3495(02)75616-6  0.783
2002 Berry SM, Gieselman MD, Nilges MJ, van Der Donk WA, Lu Y. An engineered azurin variant containing a selenocysteine copper ligand. Journal of the American Chemical Society. 124: 2084-5. PMID 11878940 DOI: 10.1021/Ja0169163  0.803
2001 Pfister TD, Gengenbach AJ, Syn S, Lu Y. The role of redox-active amino acids on compound I stability, substrate oxidation, and protein cross-linking in yeast cytochrome C peroxidase. Biochemistry. 40: 14942-51. PMID 11732914 DOI: 10.1021/Bi011400H  0.791
2001 Lu Y, Berry SM, Pfister TD. Engineering novel metalloproteins: design of metal-binding sites into native protein scaffolds. Chemical Reviews. 101: 3047-80. PMID 11710062 DOI: 10.1021/Cr0000574  0.802
2001 Sigman JA, Wang X, Lu Y. Coupled oxidation of heme by myoglobin is mediated by exogenous peroxide. Journal of the American Chemical Society. 123: 6945-6. PMID 11448209 DOI: 10.1021/Ja015776U  0.761
2001 DeBeer George S, Metz M, Szilagyi RK, Wang H, Cramer SP, Lu Y, Tolman WB, Hedman B, Hodgson KO, Solomon EI. A quantitative description of the ground-state wave function of Cu(A) by X-ray absorption spectroscopy: comparison to plastocyanin and relevance to electron transfer. Journal of the American Chemical Society. 123: 5757-67. PMID 11403610 DOI: 10.1021/Ja004109I  0.635
2001 Gengenbach A, Wang X, Lu Y. Designing a manganese peroxidase Acs Symposium Series. 785: 487-500.  0.803
2000 Hay MT, Lu Y. Metal-binding properties of an engineered purple CuA center in azurin. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 5: 699-712. PMID 11128997 DOI: 10.1007/S007750000158  0.735
2000 Berry SM, Wang X, Lu Y. Ligand replacement study at the His120 site of purple CuA azurin. Journal of Inorganic Biochemistry. 78: 89-95. PMID 10714710 DOI: 10.1016/S0162-0134(99)00214-7  0.781
2000 Franco R, Ma JG, Lu Y, Ferreira GC, Shelnutt JA. Porphyrin interactions with wild-type and mutant mouse ferrochelatase. Biochemistry. 39: 2517-29. PMID 10704201 DOI: 10.1021/Bi991346T  0.387
2000 Li J, Zheng W, Kwon AH, Lu Y. In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme Nucleic Acids Research. 28: 481-488. PMID 10606646 DOI: 10.1093/Nar/28.2.481  0.377
2000 Sigman JA, Kwok BC, Lu Y. From myoglobin to heme-copper oxidase: Design and engineering of a Cu(B) center into sperm whale myoglobin Journal of the American Chemical Society. 122: 8192-8196. DOI: 10.1021/Ja0015343  0.811
1999 Gengenbach A, Syn S, Wang X, Lu Y. Redesign of cytochrome c peroxidase into a manganese peroxidase: Role of tryptophans in peroxidase activity Biochemistry. 38: 11425-11432. PMID 10471293 DOI: 10.1021/Bi990666+  0.783
1999 Sigman JA, Pond AE, Dawson JH, Lu Y. Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation. Biochemistry. 38: 11122-9. PMID 10460168 DOI: 10.1021/Bi990815O  0.8
1999 Wang X, Lu Y. Proton NMR Investigation of the Heme Active Site Structure of an Engineered Cytochrome c Peroxidase that Mimics Manganese Peroxidase Biochemistry. 38: 9146-9157. PMID 10413489 DOI: 10.1021/Bi990235R  0.358
1999 Robinson H, Ang MC, Gao YG, Hay MT, Lu Y, Wang AH. Structural basis of electron transfer modulation in the purple CuA center. Biochemistry. 38: 5677-83. PMID 10231517 DOI: 10.1021/Bi9901634  0.807
1999 Nguyen TH, Cunningham LA, Hammond KM, Lu Y. High-resolution preparative-scale purification of RNA using the Prep Cell. Analytical Biochemistry. 269: 216-8. PMID 10094802 DOI: 10.1006/Abio.1999.4030  0.574
1999 Farver O, Lu Y, Ang MC, Pecht I. Enhanced rate of intramolecular electron transfer in an engineered purple CuA azurin. Proceedings of the National Academy of Sciences of the United States of America. 96: 899-902. PMID 9927665 DOI: 10.1073/Pnas.96.3.899  0.746
1999 Wang X, Berry SM, Xia Y, Lu Y. The role of histidine ligands in the structure of purple Cu(A) azurin [23] Journal of the American Chemical Society. 121: 7449-7450. DOI: 10.1021/Ja991304S  0.778
1999 Sigman JA, Kwok BC, Gengenbach A, Lu Y. Design and creation of a Cu(II)-binding site in cytochrome c peroxidase that mimics the Cu(B)-heme center in terminal oxidases [5] Journal of the American Chemical Society. 121: 8949-8950. DOI: 10.1021/Ja991195H  0.797
1999 Wang X, Ang MC, Lu Y. Kinetics of copper incorporation into an engineered purple azurin Journal of the American Chemical Society. 121: 2947-2948. DOI: 10.1021/Ja982636K  0.724
1998 Cunningham LA, Li J, Lu Y. Spectroscopic evidence for inner-sphere coordination of metal ions to the active site of a hammerhead ribozyme Journal of the American Chemical Society. 120: 4518-4519. DOI: 10.1021/Ja973251P  0.645
1998 Gamelin DR, Randall DW, Hay MT, Houser RP, Mulder TC, Canters GW, De Vries S, Tolman WB, Lu Y, Solomon EI. Spectroscopy of mixed-valence Cu(A)-type centers: Ligand-field control of ground-state properties related to electron transfer Journal of the American Chemical Society. 120: 5246-5263. DOI: 10.1021/Ja973161K  0.743
1998 Hay MT, Ang MC, Gamelin DR, Solomon EI, Antholine WE, Ralle M, Blackburn NJ, Massey PD, Wang X, Kwon AH, Lu Y. Spectroscopic Characterization of an Engineered Purple CuACenter in Azurin Inorganic Chemistry. 37: 191-198. DOI: 10.1021/Ic971232A  0.789
1998 Blackburn NJ, Ralle M, Sanders D, Fee JA, De Vries S, Houser RP, Tolman WB, Hay MT, Lu Y. XAS Studies on the CuA Centers of Heme-Copper Oxidases and Loop-Directed Mutants of Azurin: Implications for Redox Reactivity Acs Symposium Series. 692: 241-259.  0.684
1997 Lu Y, Valentine JS. Engineering metal-binding sites in proteins. Current Opinion in Structural Biology. 7: 495-500. PMID 9266170 DOI: 10.1016/S0959-440X(97)80112-1  0.561
1997 Yeung BK, Wang X, Sigman JA, Petillo PA, Lu Y. Construction and characterization of a manganese-binding site in cytochrome c peroxidase: towards a novel manganese peroxidase. Chemistry & Biology. 4: 215-21. PMID 9115415 DOI: 10.1016/S1074-5521(97)90291-X  0.8
1996 Lu Y, Roe JA, Bender CJ, Peisach J, Banci L, Bertini I, Gralla EB, Valentine JS. New Type 2 Copper-Cysteinate Proteins. Copper Site Histidine-to-Cysteine Mutants of Yeast Copper-Zinc Superoxide Dismutase. Inorganic Chemistry. 35: 1692-1700. PMID 11666393 DOI: 10.1021/Ic9513189  0.569
1996 Cunningham L, Kittikamron K, Lu Y. Preparative-Scale Purification of RNA Using an Efficient Method Which Combines Gel Electrophoresis and Column Chromatography Nucleic Acids Research. 24: 3647-3648. PMID 8836197 DOI: 10.1093/Nar/24.18.3647  0.584
1996 Hay M, Richards JH, Lu Y. Construction and characterization of an azurin analog for the purple copper site in cytochrome c oxidase Proceedings of the National Academy of Sciences of the United States of America. 93: 461-464. PMID 8552661 DOI: 10.1073/Pnas.93.1.461  0.723
1996 Hay MT, Milberg RM, Lu Y. Preparation and characterization of mercury and silver derivatives of an engineered purple copper center in azurin Journal of the American Chemical Society. 118: 11976-11977. DOI: 10.1021/Ja962280H  0.725
1995 Andrew CR, Lappalainen P, Saraste M, Hay MT, Lu Y, Dennison C, Canters GW, Fee JA, Slutter CE, Nakamura N, Sanders-Loehr J. Engineered cupredoxins and bacterial cytochrome c oxidases have similar CuA sites: Evidence from resonance Raman spectroscopy Journal of the American Chemical Society. 117: 10759-10760. DOI: 10.1021/Ja00148A025  0.677
1995 Lu Y, Hay MT, Richards JH. Turning a blue copper protein into a purple copper protein: Making protein analogs to the CuA site of cytochrome C oxidase and the copper center in nitrous oxide reductase Journal of Inorganic Biochemistry. 59: 702. DOI: 10.1016/0162-0134(95)97790-W  0.713
1993 Lu Y, Casimiro DR, Bren KL, Richards JH, Gray HB. Structurally engineered cytochromes with unusual ligand-binding properties: expression of Saccharomyces cerevisiae Met-80-->Ala iso-1-cytochrome c. Proceedings of the National Academy of Sciences of the United States of America. 90: 11456-9. PMID 8265573 DOI: 10.1073/Pnas.90.24.11456  0.68
1993 Lu Y, LaCroix LB, Lowery MD, Solomon EI, Bender CJ, Peisach J, Roe JA, Gralla EB, Valentine JS. Construction of a blue copper site at the native zinc site of yeast copper-zinc superoxide dismutase Journal of the American Chemical Society. 115: 5907-5918. DOI: 10.1021/Ja00067A003  0.637
1993 Han J, Loehr TM, Lu Y, Valentine JS, Averill BA, Sanders-Loehr J. Resonance raman excitation profiles indicate multiple cys → Cu charge transfer transitions in type 1 copper proteins Journal of the American Chemical Society. 115: 4256-4263. DOI: 10.1021/Ja00063A048  0.55
1993 Yeom H, Lu Y, Andrew C, Sanders-Loehr J, Gralla E, Valentine J. Probing the active site of yeast copper-zinc SOD with cysteine. Journal of Inorganic Biochemistry. 51: 135. DOI: 10.1016/0162-0134(93)85171-4  0.552
1993 Lu Y, Rennecker J, Di Bilio AJ, Chang I, Casimiro DR, Winkler JR, Valentine JS, Gray HB. Electron-transfer properties of ruthenated yeast Cu-Zn superoxide dismutase mutants. Journal of Inorganic Biochemistry. 51: 109. DOI: 10.1016/0162-0134(93)85145-X  0.684
1993 Lu Y, Casimiro DR, Winkler JR, Richards JH, Gray HB. Expression and purification of the nonfunctional Met80Ala mutant of yeast iso-1-cytochrome c. Journal of Inorganic Biochemistry. 51: 108. DOI: 10.1016/0162-0134(93)85144-W  0.541
1992 Lu Y, Gralla EB, Roe JA, Valentine JS. The redesign of a type 2 into a type 1 copper protein: construction and characterization of yeast copper, zinc superoxide dismutase mutants Journal of the American Chemical Society. 114: 3560-3562. DOI: 10.1021/Ja00035A064  0.476
1992 Valentine JS, Lu Y, Graden JA, Yeom H, Gralla EB. Copper protein ligand redesign: Characterizations of yeast Cu, Zn superoxide dismutase active site mutants Journal of Inorganic Biochemistry. 47: 34. DOI: 10.1016/0162-0134(92)84105-V  0.573
1991 Lu Y, Gralla E, Roe J, Valentine J. The redesign of a type II into a type I copper protein: Construction, expression, purification and spectroscopic characterization of yeast Cu,Zn superoxide dismutase mutants Journal of Inorganic Biochemistry. 43: 184. DOI: 10.1016/0162-0134(91)84176-A  0.547
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