Toru Ouchi - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Biology, Cell Biology, Oncology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Katsuta E, Sawant Dessai A, Ebos JM, Yan L, Ouchi T, Takabe K. H2AX mRNA expression reflects DNA repair, cell proliferation, metastasis, and worse survival in breast cancer. American Journal of Cancer Research. 12: 793-804. PMID 35261802  0.396
2015 Sancho SC, Ouchi T. Cell Differentiation and Checkpoint. International Journal of Cancer Research and Molecular Mechanisms. 1. PMID 26998525 DOI: 10.16966/2381-3318.107  0.465
2015 Ouchi M, Fujiuchi N, Sasai K, Katayama H, Minamishima YA, Ongusaha PP, Deng C, Sen S, Lee SW, Ouchi T. BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition. The Journal of Biological Chemistry. 290: 22311. PMID 26341884 DOI: 10.1074/Jbc.A115.311780  0.327
2015 So EY, Ouchi M, Cuesta-Sancho S, Olson SL, Reif D, Shimomura K, Ouchi T. Tumor suppression by resistant maltodextrin, Fibersol-2. Cancer Biology & Therapy. 16: 460-5. PMID 25692338 DOI: 10.1080/15384047.2015.1009269  0.326
2015 Low LH, Chow YL, Li Y, Goh CP, Putz U, Silke J, Ouchi T, Howitt J, Tan SS. Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response. The Journal of Biological Chemistry. 290: 7141-50. PMID 25631046 DOI: 10.1074/jbc.M114.613687  0.52
2014 Ouchi M, Ouchi T. Distinct DNA damage determines differential phosphorylation of Chk2. Cancer Biology & Therapy. 15: 1700-4. PMID 25535901 DOI: 10.4161/15384047.2014.972823  0.555
2014 So EY, Ouchi T. BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunction. Bmc Cancer. 14: 548. PMID 25070371 DOI: 10.1186/1471-2407-14-548  0.431
2014 So EY, Ouchi T. Decreased DNA repair activity in bone marrow due to low expression of DNA damage repair proteins. Cancer Biology & Therapy. 15: 906-10. PMID 24755532 DOI: 10.4161/Cbt.28883  0.462
2013 So EY, Ouchi T. The Potential Role of BRCA1-Associated ATM Activator-1 (BRAT1) in Regulation of mTOR. Journal of Cancer Biology & Research. 1. PMID 25657994  0.502
2013 So EY, Kozicki M, Ouchi T. Roles of DNA Damage Response Proteins in Mitogen-Induced Thp-1 Differentiation into Macrophage. Journal of Cancer Biology & Research. 1. PMID 25654138  0.454
2013 Shionome Y, Lin WH, Shiao HY, Hsieh HP, Hsu JT, Ouchi T. A novel aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment. International Journal of Biological Sciences. 9: 403-11. PMID 23678290 DOI: 10.7150/Ijbs.5806  0.498
2013 Shionome Y, Yan L, Liu S, Saeki T, Ouchi T. Integrity of p53 associated pathways determines induction of apoptosis of tumor cells resistant to Aurora-A kinase inhibitors. Plos One. 8: e55457. PMID 23383195 DOI: 10.1371/journal.pone.0055457  0.452
2012 Jeon GS, Kim KY, Hwang YJ, Jung MK, An S, Ouchi M, Ouchi T, Kowall N, Lee J, Ryu H. Deregulation of BRCA1 leads to impaired spatiotemporal dynamics of γ-H2AX and DNA damage responses in Huntington's disease. Molecular Neurobiology. 45: 550-63. PMID 22580959 DOI: 10.1007/S12035-012-8274-9  0.506
2012 Kang MA, So EY, Ouchi T. Deregulation of DNA damage response pathway by intercellular contact. The Journal of Biological Chemistry. 287: 16246-55. PMID 22431734 DOI: 10.1074/Jbc.M111.337212  0.603
2012 Shih HJ, Chu KL, Wu MH, Wu PH, Chang WW, Chu JS, Wang LH, Takeuchi H, Ouchi T, Hsu HL. The involvement of MCT-1 oncoprotein in inducing mitotic catastrophe and nuclear abnormalities. Cell Cycle (Georgetown, Tex.). 11: 934-52. PMID 22336915 DOI: 10.4161/cc.11.5.19452  0.437
2011 So EY, Ouchi T. Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit. Experimental and Therapeutic Medicine. 2: 443-447. PMID 22977523 DOI: 10.3892/Etm.2011.232  0.562
2011 So EY, Ausman M, Saeki T, Ouchi T. Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis. Cell Death and Disease. 2. PMID 21390062 DOI: 10.1038/Cddis.2011.9  0.676
2010 Ouchi M, Ouchi T. Regulation of ATM/DNA-PKcs Phosphorylation by BRCA1-Associated BAAT1. Genes & Cancer. 1: 1211-4. PMID 21779444 DOI: 10.1177/1947601911404222  0.549
2010 Shukla V, Coumoul X, Lahusen T, Wang RH, Xu X, Vassilopoulos A, Xiao C, Lee MH, Man YG, Ouchi M, Ouchi T, Deng CX. BRCA1 affects global DNA methylation through regulation of DNMT1. Cell Research. 20: 1201-15. PMID 20820192 DOI: 10.1038/Cr.2010.128  0.471
2009 Saeki T, Ouchi M, Ouchi T. Physiological and oncogenic Aurora-A pathway. International Journal of Biological Sciences. 5: 758-62. PMID 20011137 DOI: 10.7150/Ijbs.5.758  0.41
2009 Taga M, Hirooka E, Ouchi T. Essential roles of mTOR/Akt pathway in Aurora-A cell transformation. International Journal of Biological Sciences. 5: 444-50. PMID 19564927 DOI: 10.7150/Ijbs.5.444  0.524
2008 Martin SA, Ouchi T. Cellular commitment to reentry into the cell cycle after stalled DNA is determined by site-specific phosphorylation of Chk1 and PTEN Molecular Cancer Therapeutics. 7: 2509-2516. PMID 18723495 DOI: 10.1158/1535-7163.Mct-08-0199  0.582
2008 Yamamoto K, Nihrane A, Aglipay J, Sironi J, Arkin S, Lipton JM, Ouchi T, Liu JM. Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis. Molecular Medicine (Cambridge, Mass.). 14: 167-74. PMID 18224251 DOI: 10.2119/2007-00122.Yamamoto  0.579
2008 Tawara H, Fujiuchi N, Sironi J, Martin S, Aglipay J, Ouchi M, Taga M, Chen PL, Ouchi T. Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpoint by phosphorylation of p53 SER37. Frontiers in Bioscience : a Journal and Virtual Library. 13: 240-8. PMID 17981542 DOI: 10.2741/2674  0.579
2008 Ouchi M, Ouchi T. Role of IFI16 in DNA damage and checkpoint. Frontiers in Bioscience : a Journal and Virtual Library. 13: 236-9. PMID 17981541 DOI: 10.2741/2673  0.604
2006 Ouchi T. BRCA1 phosphorylation: biological consequences. Cancer Biology & Therapy. 5: 470-5. PMID 16721040 DOI: 10.4161/Cbt.5.5.2845  0.591
2006 Cruz CD, Palosaari H, Parisien JP, Devaux P, Cattaneo R, Ouchi T, Horvath CM. Measles virus V protein inhibits p53 family member p73. Journal of Virology. 80: 5644-50. PMID 16699046 DOI: 10.1128/Jvi.02400-05  0.437
2006 Aglipay JA, Martin SA, Tawara H, Lee SW, Ouchi T. ATM activation by ionizing radiation requires BRCA1-associated BAAT1. The Journal of Biological Chemistry. 281: 9710-8. PMID 16452482 DOI: 10.1074/Jbc.M510332200  0.632
2005 Martin SA, Ouchi T. BRCA1 phosphorylation regulates caspase-3 activation in UV-induced apoptosis Cancer Research. 65: 10657-10662. PMID 16322207 DOI: 10.1158/0008-5472.Can-05-2087  0.537
2005 Yamamoto K, Ouchi T, Liu JM. Heightened Activation of the p53-ATM Axis in Fanconi Anemia Mutant-Derived Primary Cells: Implications for Carcinogenesis. Blood. 106: 1055-1055. DOI: 10.1182/Blood.V106.11.1055.1055  0.63
2004 Fujiuchi N, Aglipay JA, Ohtsuka T, Maehara N, Sahin F, Su GH, Lee SW, Ouchi T. Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation. The Journal of Biological Chemistry. 279: 20339-44. PMID 14990579 DOI: 10.1074/Jbc.M400344200  0.595
2004 Ouchi M, Fujiuchi N, Sasai K, Katayama H, Minamishima YA, Ongusaha PP, Deng C, Sen S, Lee SW, Ouchi T. BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition. The Journal of Biological Chemistry. 279: 19643-8. PMID 14990569 DOI: 10.1074/Jbc.M311780200  0.499
2004 Sironi JJ, Ouchi T. STAT1-induced apoptosis is mediated by caspases 2, 3, and 7. The Journal of Biological Chemistry. 279: 4066-74. PMID 14623896 DOI: 10.1074/Jbc.M307774200  0.429
2003 Aglipay JA, Lee SW, Okada S, Fujiuchi N, Ohtsuka T, Kwak JC, Wang Y, Johnstone RW, Deng C, Qin J, Ouchi T. A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway. Oncogene. 22: 8931-8. PMID 14654789 DOI: 10.1038/Sj.Onc.1207057  0.608
2003 Kwak JC, Ongusaha PP, Ouchi T, Lee SW. IFI16 as a negative regulator in the regulation of p53 and p21(Waf1). The Journal of Biological Chemistry. 278: 40899-904. PMID 12925527 DOI: 10.1074/jbc.M308012200  0.452
2003 Ongusaha PP, Ouchi T, Kim KT, Nytko E, Kwak JC, Duda RB, Deng CX, Lee SW. BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest. Oncogene. 22: 3749-58. PMID 12802282 DOI: 10.1038/Sj.Onc.1206439  0.542
2003 Abramovitch S, Glaser T, Ouchi T, Werner H. BRCA1-Sp1 interactions in transcriptional regulation of the IGF-IR gene. Febs Letters. 541: 149-54. PMID 12706836 DOI: 10.1016/S0014-5793(03)00315-6  0.437
2003 Okada S, Ouchi T. Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization. The Journal of Biological Chemistry. 278: 2015-20. PMID 12427729 DOI: 10.1074/Jbc.M208685200  0.561
2002 Chen A, Kleiman FE, Manley JL, Ouchi T, Pan ZQ. Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase. The Journal of Biological Chemistry. 277: 22085-92. PMID 11927591 DOI: 10.1074/Jbc.M201252200  0.42
2000 Arizti P, Fang L, Park I, Yin Y, Solomon E, Ouchi T, Aaronson SA, Lee SW. Tumor suppressor p53 is required to modulate BRCA1 expression. Molecular and Cellular Biology. 20: 7450-9. PMID 11003642 DOI: 10.1128/Mcb.20.20.7450-7459.2000  0.613
2000 Lee SW, Fang L, Igarashi M, Ouchi T, Lu KP, Aaronson SA. Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53. Proceedings of the National Academy of Sciences of the United States of America. 97: 8302-5. PMID 10890907 DOI: 10.1073/Pnas.150024397  0.582
2000 Shishido T, Akagi T, Ouchi T, Georgescu MM, Langdon WY, Hanafusa H. The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 97: 6439-44. PMID 10829062 DOI: 10.1073/Pnas.060030697  0.392
2000 Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM. Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes. Proceedings of the National Academy of Sciences of the United States of America. 97: 5208-13. PMID 10792030 DOI: 10.1073/Pnas.080469697  0.434
1998 Marmorstein LY, Ouchi T, Aaronson SA. The BRCA2 gene product functionally interacts with p53 and RAD51. Proceedings of the National Academy of Sciences of the United States of America. 95: 13869-74. PMID 9811893 DOI: 10.1073/Pnas.95.23.13869  0.585
1997 Tanaka S, Ouchi T, Hanafusa H. Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G. Proceedings of the National Academy of Sciences of the United States of America. 94: 2356-61. PMID 9122199 DOI: 10.1073/Pnas.94.6.2356  0.414
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