Carl A. Gregory - Publications

Affiliations: 
Biomedical Sciences Tulane University, New Orleans, LA, United States 
Area:
Cell Biology, Molecular Biology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Haskell A, White BP, Rogers RE, Goebel E, Lopez MG, Syvyk AE, de Oliveira DA, Barreda HA, Benton J, Benavides OR, Dalal S, Bae E, Zhang Y, Maitland K, Nikolov Z, ... ... Gregory CA, et al. Scalable manufacture of therapeutic mesenchymal stromal cell products on customizable microcarriers in vertical wheel bioreactors that improve direct visualization, product harvest, and cost. Cytotherapy. PMID 38363250 DOI: 10.1016/j.jcyt.2024.01.009  0.311
2023 Lee RH, Boregowda SV, Shigemoto-Kuroda T, Bae E, Haga CL, Abbery CA, Bayless KJ, Haskell A, Gregory CA, Ortiz LA, Phinney DG. and are coordinately regulated and function as potency biomarkers in human MSCs. Science Advances. 9: eadi2387. PMID 37948519 DOI: 10.1126/sciadv.adi2387  0.369
2023 Benavides OR, Gibbs HC, White BP, Kaunas R, Gregory CA, Walsh AJ, Maitland KC. Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth. Plos One. 18: e0282298. PMID 36976801 DOI: 10.1371/journal.pone.0282298  0.309
2022 MacIver MA, Dobson LK, Gregory CA, Muneoka K, Saunders WB. A three-dimensional (3D), serum-free, Collagen Type I system for chondrogenesis of canine bone marrow-derived multipotent stromal cells (cMSCs). Plos One. 17: e0269571. PMID 35679245 DOI: 10.1371/journal.pone.0269571  0.341
2022 Brokesh AM, Cross LM, Kersey AL, Murali A, Richter C, Gregory CA, Singh I, Gaharwar AK. Dissociation of nanosilicates induces downstream endochondral differentiation gene expression program. Science Advances. 8: eabl9404. PMID 35476448 DOI: 10.1126/sciadv.abl9404  0.335
2021 Dobson LK, Zeitouni S, McNeill EP, Bearden RN, Gregory CA, Saunders WB. Canine Mesenchymal Stromal Cell-Mediated Bone Regeneration is Enhanced in the Presence of Sub-Therapeutic Concentrations of BMP-2 in a Murine Calvarial Defect Model. Frontiers in Bioengineering and Biotechnology. 9: 764703. PMID 34796168 DOI: 10.3389/fbioe.2021.764703  0.498
2021 Rogers RE, Haskell A, White BP, Dalal S, Lopez M, Tahan D, Pan S, Kaur G, Kim H, Barreda H, Woodard SL, Benavides OR, Dai J, Zhao Q, Maitland KC, ... ... Gregory CA, et al. A scalable system for generation of mesenchymal stem cells derived from induced pluripotent cells employing bioreactors and degradable microcarriers. Stem Cells Translational Medicine. PMID 34505405 DOI: 10.1002/sctm.21-0151  0.397
2021 Mota SM, Rogers RE, Haskell AW, McNeill EP, Kaunas R, Gregory CA, Giger ML, Maitland KC. Automated mesenchymal stem cell segmentation and machine learning-based phenotype classification using morphometric and textural analysis. Journal of Medical Imaging (Bellingham, Wash.). 8: 014503. PMID 33542945 DOI: 10.1117/1.JMI.8.1.014503  0.32
2020 Gasson SB, Dobson LK, Chow L, Dow SW, Gregory CA, Saunders WB. Optimizing in vitro osteogenesis in canine autologous and induced pluripotent stem cell-derived mesenchymal stromal cells with dexamethasone and BMP-2. Stem Cells and Development. PMID 33356875 DOI: 10.1089/scd.2020.0144  0.418
2020 Mondragón E, Cowdin M, Taraballi F, Minardi S, Tasciotti E, Gregory CA, Kaunas R. Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties. Frontiers in Bioengineering and Biotechnology. 8: 753. PMID 32719790 DOI: 10.3389/Fbioe.2020.00753  0.571
2020 McNeill EP, Zeitouni S, Pan S, Haskell A, Cesarek M, Tahan D, Clough BH, Krause U, Dobson LK, Garcia M, Kung C, Zhao Q, Saunders WB, Liu F, Kaunas R, ... Gregory CA, et al. Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities. Nature Communications. 11: 3025. PMID 32541821 DOI: 10.1038/S41467-020-16646-2  0.612
2020 Gregory CA, McNeill EP, Pan S. Preparation of osteogenic matrices from cultured cells. Methods in Cell Biology. 156: 15-43. PMID 32222217 DOI: 10.1016/Bs.Mcb.2019.10.009  0.538
2020 Sears C, Mondragon E, Richards ZI, Sears N, Chimene D, McNeill EP, Gregory CA, Gaharwar AK, Kaunas R. Conditioning of 3D Printed Nanoengineered Ionic-Covalent Entanglement Scaffolds with iP-hMSCs Derived Matrix. Advanced Healthcare Materials. e1901580. PMID 32147960 DOI: 10.1002/Adhm.201901580  0.579
2019 Xin S, Gregory C, Alge DL. Interplay Between Degradability and Integrin Signaling on Mesenchymal Stem Cell Function within Poly(ethylene glycol) Based Microporous Annealed Particle Hydrogels. Acta Biomaterialia. PMID 31711899 DOI: 10.1016/J.Actbio.2019.11.009  0.441
2018 McNeill EP, Reese RW, Tondon A, Clough BH, Pan S, Froese J, Palmer D, Krause U, Loeb DM, Kaunas R, Gregory CA. Three-dimensional in vitro modeling of malignant bone disease recapitulates experimentally accessible mechanisms of osteoinhibition. Cell Death & Disease. 9: 1161. PMID 30478297 DOI: 10.1038/S41419-018-1203-8  0.54
2018 Rowland AL, Xu JJ, Joswig AJ, Gregory CA, Antczak DF, Cummings KJ, Watts AE. In vitro MSC function is related to clinical reaction in vivo. Stem Cell Research & Therapy. 9: 295. PMID 30409211 DOI: 10.1186/S13287-018-1037-4  0.436
2018 Chaput CD, Shar A, Jupiter D, Hubert Z, Clough B, Krause U, Gregory CA. How stem cell composition in bone marrow aspirate relates to clinical outcomes when used for cervical spine fusion. Plos One. 13: e0203714. PMID 30248138 DOI: 10.1371/Journal.Pone.0203714  0.537
2018 Carrow JK, Cross LM, Reese RW, Jaiswal MK, Gregory CA, Kaunas R, Singh I, Gaharwar AK. Widespread changes in transcriptome profile of human mesenchymal stem cells induced by two-dimensional nanosilicates. Proceedings of the National Academy of Sciences of the United States of America. PMID 29643075 DOI: 10.1073/Pnas.1716164115  0.412
2018 Clough BH, Zeitouni S, Krause U, Chaput CD, Cross LM, Gaharwar AK, Gregory CA. Rapid Osteogenic Enhancement of Stem Cells in Human Bone Marrow Using a Glycogen-Synthease-Kinase-3-Beta Inhibitor Improves Osteogenic Efficacy In Vitro and In Vivo. Stem Cells Translational Medicine. PMID 29405665 DOI: 10.1002/Sctm.17-0229  0.588
2018 MacIver M, Dobson L, Muneoka K, Gregory C, Saunders W. Development of a 3D Type I Collagen Assay to Evaluate Chondrogenesis of Canine Bone Marrow-Derived Mesenchymal Stem Cells Veterinary and Comparative Orthopaedics and Traumatology. 31: A1-A25. DOI: 10.1055/S-0038-1668228  0.574
2018 Dobson LK, Zeitouni S, McNeill EP, Gregory CA, Saunders WB. Canine Mesenchymal Stem Cell-Mediated Bone Regeneration is Enhanced in the Presence of Sub-Therapeutic Concentrations of Rhbmp-2 in a Murine Critical-Sized Calvarial Defect Veterinary and Comparative Orthopaedics and Traumatology. 31. DOI: 10.1055/S-0038-1668219  0.569
2017 Zeitouni J, Clough B, Zeitouni S, Saleem M, Al Aisami K, Gregory C. The effects of the Er:YAG laser on trabecular bone micro-architecture: Comparison with conventional dental drilling by micro-computed tomographic and histological techniques. F1000research. 6: 1133. PMID 29416849 DOI: 10.12688/F1000Research.12018.1  0.383
2017 Dosch J, Hadley E, Wiese C, Soderberg M, Houwman T, Ding K, Kharazova A, Collins JL, van Knippenberg B, Gregory C, Kofman A. Time-lapse microscopic observation of non-dividing cells in cultured human osteosarcoma MG-63 cell line. Cell Cycle (Georgetown, Tex.). 1-25. PMID 29169283 DOI: 10.1080/15384101.2017.1395535  0.454
2017 Bearden RN, Huggins SS, Cummings KJ, Smith R, Gregory CA, Saunders WB. In-vitro characterization of canine multipotent stromal cells isolated from synovium, bone marrow, and adipose tissue: a donor-matched comparative study. Stem Cell Research & Therapy. 8: 218. PMID 28974260 DOI: 10.1186/S13287-017-0639-6  0.544
2017 Joswig AJ, Mitchell A, Cummings KJ, Levine GJ, Gregory CA, Smith R, Watts AE. Repeated intra-articular injection of allogeneic mesenchymal stem cells causes an adverse response compared to autologous cells in the equine model. Stem Cell Research & Therapy. 8: 42. PMID 28241885 DOI: 10.1186/S13287-017-0503-8  0.45
2017 Ullah M, Kuroda Y, Bartosh TJ, Liu F, Zhao Q, Gregory C, Reger R, Xu J, Lee RH, Prockop DJ. iPS-derived MSCs from an expandable bank to deliver a prodrug-converting enzyme that limits growth and metastases of human breast cancers. Cell Death Discovery. 3: 16064. PMID 28179988 DOI: 10.1038/Cddiscovery.2016.64  0.438
2016 Clough BH, Ylostalo J, Browder E, McNeill EP, Bartosh TJ, Rawls HR, Nakamoto T, Gregory CA. Theobromine Upregulates Osteogenesis by Human Mesenchymal Stem Cells In Vitro and Accelerates Bone Development in Rats. Calcified Tissue International. PMID 27913821 DOI: 10.1007/S00223-016-0215-6  0.524
2016 Yun YI, Park SY, Lee HJ, Ko JH, Kim MK, Wee WR, Reger RL, Gregory CA, Choi H, Fulcher SF, Prockop DJ, Oh JY. Comparison of the anti-inflammatory effects of induced pluripotent stem cell-derived and bone marrow-derived mesenchymal stromal cells in a murine model of corneal injury. Cytotherapy. PMID 27840134 DOI: 10.1016/J.Jcyt.2016.10.007  0.503
2016 Clough BH, McNeill EP, Palmer D, Krause U, Bartosh TJ, Chaput CD, Gregory CA. An allograft generated from adult stem cells and their secreted products efficiently fuses vertebrae in immune compromised athymic rats and inhibits local immune responses. The Spine Journal : Official Journal of the North American Spine Society. PMID 27765715 DOI: 10.1016/J.Spinee.2016.10.009  0.475
2016 Spees JL, Lee RH, Gregory CA. Mechanisms of mesenchymal stem/stromal cell function. Stem Cell Research & Therapy. 7: 125. PMID 27581859 DOI: 10.1186/S13287-016-0363-7  0.511
2015 Clough BH, McCarley MR, Gregory CA. A simple critical-sized femoral defect model in mice. Journal of Visualized Experiments : Jove. PMID 25867551 DOI: 10.3791/52368  0.492
2015 Zhao Q, Gregory CA, Lee RH, Reger RL, Qin L, Hai B, Park MS, Yoon N, Clough B, McNeill E, Prockop DJ, Liu F. MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs. Proceedings of the National Academy of Sciences of the United States of America. 112: 530-5. PMID 25548183 DOI: 10.1073/Pnas.1423008112  0.443
2015 Clough BH, McCarley MR, Krause U, Zeitouni S, Froese JJ, McNeill EP, Chaput CD, Sampson HW, Gregory CA. Bone regeneration with osteogenically enhanced mesenchymal stem cells and their extracellular matrix proteins. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 83-94. PMID 25130615 DOI: 10.1002/Jbmr.2320  0.568
2015 Gregory CA, Clough B, Chaput CD. Stem Cell-Derived Live Bone Mimics for Superior Spinal Arthrodesis The Spine Journal. 15. DOI: 10.1016/J.Spinee.2015.07.238  0.556
2014 Krause U, Ryan DM, Clough BH, Gregory CA. An unexpected role for a Wnt-inhibitor: Dickkopf-1 triggers a novel cancer survival mechanism through modulation of aldehyde-dehydrogenase-1 activity. Cell Death & Disease. 5: e1093. PMID 24577091 DOI: 10.1038/Cddis.2014.67  0.472
2013 Murphy MB, Suzuki RK, Sand TT, Chaput CD, Gregory CA. Short Term Culture of Human Mesenchymal Stem Cells with Commercial Osteoconductive Carriers Provides Unique Insights into Biocompatibility. Journal of Clinical Medicine. 2: 49-66. PMID 26237062 DOI: 10.3390/Jcm2030049  0.568
2012 Zeitouni S, Krause U, Clough BH, Halderman H, Falster A, Blalock DT, Chaput CD, Sampson HW, Gregory CA. Human mesenchymal stem cell-derived matrices for enhanced osteoregeneration. Science Translational Medicine. 4: 132ra55. PMID 22553253 DOI: 10.1126/Scitranslmed.3003396  0.579
2012 Krause U, Gregory CA. Potential of modulating Wnt signaling pathway toward the development of bone anabolic agent. Current Molecular Pharmacology. 5: 164-73. PMID 21787289 DOI: 10.2174/1874467211205020164  0.519
2012 Zeitouni S, Krause U, Clough BH, Halderman H, Falster A, Blalock DT, Chaput CD, Sampson HW, Gregory CA. Human mesenchymal stem cell-derived matrices for enhanced osteoregeneration (Science Translational Medicine (2012) 4, (149er5)) Science Translational Medicine. 4. DOI: 10.1126/Scitranslmed.3004739  0.457
2011 Krause U, Seckinger A, Gregory CA. Assays of osteogenic differentiation by cultured human mesenchymal stem cells. Methods in Molecular Biology (Clifton, N.J.). 698: 215-30. PMID 21431522 DOI: 10.1007/978-1-60761-999-4_17  0.487
2011 Gunn WG, Krause U, Lee N, Gregory CA. Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model. Blood. 117: 1641-51. PMID 21123822 DOI: 10.1182/Blood-2010-09-308171  0.549
2010 Larson BL, Ylostalo J, Lee RH, Gregory C, Prockop DJ. Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cells. Tissue Engineering. Part A. 16: 3385-94. PMID 20626275 DOI: 10.1089/Ten.Tea.2010.0085  0.531
2010 Krause U, Harris S, Green A, Ylostalo J, Zeitouni S, Lee N, Gregory CA. Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy. Proceedings of the National Academy of Sciences of the United States of America. 107: 4147-52. PMID 20150512 DOI: 10.1073/Pnas.0914360107  0.571
2009 Bakondi B, Shimada IS, Perry A, Munoz JR, Ylostalo J, Howard AB, Gregory CA, Spees JL. CD133 identifies a human bone marrow stem/progenitor cell sub-population with a repertoire of secreted factors that protect against stroke. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1938-47. PMID 19690521 DOI: 10.1038/Mt.2009.185  0.46
2009 Block GJ, Ohkouchi S, Fung F, Frenkel J, Gregory C, Pochampally R, DiMattia G, Sullivan DE, Prockop DJ. Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1. Stem Cells (Dayton, Ohio). 27: 670-81. PMID 19267325 DOI: 10.1002/stem.20080742  0.432
2009 Lee RH, Seo MJ, Pulin AA, Gregory CA, Ylostalo J, Prockop DJ. The CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice. Blood. 113: 816-26. PMID 18818395 DOI: 10.1182/Blood-2007-12-128702  0.484
2009 Whitney MJ, Lee A, Ylostalo J, Zeitouni S, Tucker A, Gregory CA. Leukemia inhibitory factor secretion is a predictor and indicator of early progenitor status in adult bone marrow stromal cells. Tissue Engineering. Part A. 15: 33-44. PMID 18637760 DOI: 10.1089/Ten.Tea.2007.0266  0.589
2008 Zeitouni S, Ford BS, Harris SM, Whitney MJ, Gregory CA, Prockop DJ. Pharmaceutical induction of ApoE secretion by multipotent mesenchymal stromal cells (MSCs). Bmc Biotechnology. 8: 75. PMID 18823563 DOI: 10.1186/1472-6750-8-75  0.407
2007 Lee N, Smolarz AJ, Olson S, David O, Reiser J, Kutner R, Daw NC, Prockop DJ, Horwitz EM, Gregory CA. A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies. British Journal of Cancer. 97: 1552-9. PMID 17987039 DOI: 10.1038/Sj.Bjc.6604069  0.499
2007 Gregory CA. More progress defining the crosstalk between multiple myeloma and mesenchymal stem cells of the bone marrow. Leukemia & Lymphoma. 48: 1896-7. PMID 17917957 DOI: 10.1080/10428190701625115  0.613
2007 Gregory C. Advances in myeloma therapy: breaking the cycle Blood. 109: 1798-1798. DOI: 10.1182/Blood-2006-12-062067  0.385
2006 Gregory CA, Green A, Lee N, Rao A, Gunn W. The promise of canonical Wnt signaling modulators in enhancing bone repair. Drug News & Perspectives. 19: 445-52. PMID 17160144 DOI: 10.1358/Dnp.19.8.1043960  0.546
2006 Gregory CA, Reyes E, Whitney MJ, Spees JL. Enhanced engraftment of mesenchymal stem cells in a cutaneous wound model by culture in allogenic species-specific serum and administration in fibrin constructs. Stem Cells (Dayton, Ohio). 24: 2232-43. PMID 16763199 DOI: 10.1634/Stemcells.2005-0612  0.477
2006 Gunn WG, Conley A, Deininger L, Olson SD, Prockop DJ, Gregory CA. A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma. Stem Cells (Dayton, Ohio). 24: 986-91. PMID 16293576 DOI: 10.1634/Stemcells.2005-0220  0.579
2005 Gregory CA, Ylostalo J, Prockop DJ. Adult bone marrow stem/progenitor cells (MSCs) are preconditioned by microenvironmental "niches" in culture: a two-stage hypothesis for regulation of MSC fate. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe37. PMID 16046665 DOI: 10.1126/Stke.2942005Pe37  0.583
2005 Gregory CA, Gunn WG, Reyes E, Smolarz AJ, Munoz J, Spees JL, Prockop DJ. How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow. Annals of the New York Academy of Sciences. 1049: 97-106. PMID 15965110 DOI: 10.1196/Annals.1334.010  0.597
2005 Gregory CA, Prockop DJ, Spees JL. Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation. Experimental Cell Research. 306: 330-5. PMID 15925588 DOI: 10.1016/J.Yexcr.2005.03.018  0.586
2005 Gregory CA, Perry AS, Reyes E, Conley A, Gunn WG, Prockop DJ. Dkk-1-derived synthetic peptides and lithium chloride for the control and recovery of adult stem cells from bone marrow. The Journal of Biological Chemistry. 280: 2309-23. PMID 15504735 DOI: 10.1074/Jbc.M406275200  0.512
2004 Gregory CA, Gunn WG, Peister A, Prockop DJ. An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction. Analytical Biochemistry. 329: 77-84. PMID 15136169 DOI: 10.1016/J.Ab.2004.02.002  0.33
2004 Spees JL, Gregory CA, Singh H, Tucker HA, Peister A, Lynch PJ, Hsu SC, Smith J, Prockop DJ. Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 747-56. PMID 15120336 DOI: 10.1016/J.Ymthe.2004.02.012  0.535
2003 Prockop DJ, Gregory CA, Spees JL. One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair tissues. Proceedings of the National Academy of Sciences of the United States of America. 100: 11917-23. PMID 13679583 DOI: 10.1073/Pnas.1834138100  0.578
2003 Gregory CA, Singh H, Perry AS, Prockop DJ. The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow. The Journal of Biological Chemistry. 278: 28067-78. PMID 12740383 DOI: 10.1074/Jbc.M300373200  0.515
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