Thomas J. Kodadek, Ph.D. - Publications

Affiliations: 
Chemistry and Cancer Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Chemical Biology
Website:
http://www.scripps.edu/kodadek/index.html

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Dickson P, Simanski S, Ngundu JM, Kodadek T. Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11. Chemistry & Biology. PMID 32857986 DOI: 10.1016/J.Chembiol.2020.08.008  0.303
2020 McEnaney P, Balzarini M, Park H, Kodadek T. Structural characterization of a peptoid-inspired conformationally constrained oligomer (PICCO) bound to streptavidin. Chemical Communications (Cambridge, England). PMID 32785302 DOI: 10.1039/D0Cc02588G  0.761
2020 Paciaroni NG, Ndungu JM, Kodadek T. Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy. Chemical Communications (Cambridge, England). PMID 32215395 DOI: 10.1039/D0Cc01474E  0.308
2020 Roy A, Kodadek T. DELs Inside Cells. Trends in Pharmacological Sciences. PMID 32033772 DOI: 10.1016/J.Tips.2020.01.007  0.374
2019 Kodadek T, Paciaroni NG, Balzarini M, Dickson P. Beyond protein binding: recent advances in screening DNA-encoded libraries. Chemical Communications (Cambridge, England). 55: 13330-13341. PMID 31633708 DOI: 10.1039/C9Cc06256D  0.409
2019 Doran TM, Dickson P, Ndungu JM, Ge P, Suponitsky-Kroyter I, An H, Kodadek T. Synthesis and screening of bead-displayed combinatorial libraries. Methods in Enzymology. 622: 91-127. PMID 31155067 DOI: 10.1016/Bs.Mie.2019.02.005  0.735
2018 Shu K, Kodadek T. Solid-Phase Synthesis of β-Hydroxy Ketones Via DNA-Compatible Organocatalytic Aldol Reactions. Acs Combinatorial Science. PMID 29578681 DOI: 10.1021/Acscombsci.8B00001  0.356
2018 Erharuyi O, Simanski S, McEnaney PJ, Kodadek T. Screening one bead one compound libraries against serum using a flow cytometer: Determination of the minimum antibody concentration required for ligand discovery. Bioorganic & Medicinal Chemistry Letters. PMID 29395976 DOI: 10.1016/J.Bmcl.2018.01.033  0.778
2018 Hoang NT, Kodadek T. Solid-Phase Synthesis of β-Amino Ketones Via DNA-Compatible Organocatalytic Mannich Reactions. Acs Combinatorial Science. PMID 29316387 DOI: 10.1021/Acscombsci.7B00151  0.364
2018 Pels K, Dickson P, An H, Kodadek T. DNA-compatible solid-phase combinatorial synthesis of β-cyanoacrylamides and related electrophiles. Acs Combinatorial Science. PMID 29298042 DOI: 10.1021/Acscombsci.7B00169  0.356
2017 Wu H, An H, Mo SC, Kodadek T. Asymmetric synthesis of vinylogous β-amino acids and their incorporation into mixed backbone oligomers. Organic & Biomolecular Chemistry. PMID 28346549 DOI: 10.1039/C7Ob00333A  0.355
2017 Trader DJ, Simanski S, Dickson P, Kodadek T. Establishment of a suite of assays that support the discovery of proteasome stimulators. Biochimica Et Biophysica Acta. 1861: 892-899. PMID 28065760 DOI: 10.1016/J.Bbagen.2017.01.003  0.696
2016 Mendes KR, Malone ML, Ndungu JM, Suponitsky-Kroyter I, Cavett VJ, McEnaney PJ, MacConnell AB, Doran TM, Ronacher K, Stanley K, Utset O, Walzl G, Paegel BM, Kodadek T. High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections. Acs Chemical Biology. PMID 27957856 DOI: 10.1021/Acschembio.6B00855  0.791
2016 Wu H, Mousseau G, Mediouni S, Valente ST, Kodadek T. Cell-Permeable Peptides Containing Cycloalanine Residues. Angewandte Chemie (International Ed. in English). PMID 27529332 DOI: 10.1002/Anie.201605745  0.396
2016 Doran TM, Morimoto J, Simanski S, Koesema EJ, Clark LF, Pels K, Stoops SL, Pugliese A, Skyler JS, Kodadek T. Discovery of Phosphorylated Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus. Cell Chemical Biology. PMID 27185639 DOI: 10.1016/J.Chembiol.2016.04.006  0.713
2016 Gearhart TL, Montelaro RC, Schurdak ME, Pilcher CD, Rinaldo CR, Kodadek T, Park Y, Islam K, Yurko R, Marques ET, Burke DS. Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers. Journal of Immunological Methods. PMID 27182050 DOI: 10.1016/J.Jim.2016.05.001  0.385
2016 Sarma BK, Liu X, Kodadek T. Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library. Bioorganic & Medicinal Chemistry. PMID 27160052 DOI: 10.1016/J.Bmc.2016.04.047  0.755
2016 Doran TM, Sarkar M, Kodadek T. Chemical Tools to Monitor and Manipulate Adaptive Immune Responses. Journal of the American Chemical Society. PMID 27115249 DOI: 10.1021/Jacs.6B02954  0.673
2016 Kodadek T, McEnaney PJ. Towards vast libraries of scaffold-diverse, conformationally constrained oligomers. Chemical Communications (Cambridge, England). PMID 26996593 DOI: 10.1039/C6Cc00617E  0.772
2016 Sarkar M, Liu Y, Qi J, Peng H, Morimoto J, Rader C, Chiorazzi N, Kodadek T. Targeting stereotyped B cell receptors from chronic lymphocytic leukemia patients with synthetic antigen surrogates. The Journal of Biological Chemistry. PMID 26851280 DOI: 10.1074/Jbc.M115.701656  0.314
2016 Doran TM, Sarkar M, Kodadek T. ChemInform Abstract: Chemical Tools to Monitor and Manipulate Adaptive Immune Responses Cheminform. 47. DOI: 10.1002/chin.201635216  0.635
2016 Kodadek T, McEnaney PJ. ChemInform Abstract: Towards Vast Libraries of Scaffold-Diverse, Conformationally Constrained Oligomers Cheminform. 47. DOI: 10.1002/chin.201624270  0.744
2015 Doran TM, Morimoto J, Simanski S, McEnaney PJ, Kodadek T. Reliable diagnosis of murine type 1 diabetes using a panel of autoantigens and "antigen surrogates" mounted onto a liquid array. Molecular Biosystems. 11: 3156-63. PMID 26390856 DOI: 10.1039/C5Mb00521C  0.754
2015 Mendes K, Ndungu JM, Clark LF, Kodadek T. Optimization of the Magnetic Recovery of Hits from One-Bead-One-Compound Library Screens. Acs Combinatorial Science. 17: 506-17. PMID 26221913 DOI: 10.1021/Acscombsci.5B00090  0.346
2015 Doran TM, Gao Y, Simanski S, McEnaney P, Kodadek T. High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type 1 diabetes autoantibodies. Bioorganic & Medicinal Chemistry Letters. 25: 4910-7. PMID 26067174 DOI: 10.1016/J.Bmcl.2015.05.046  0.783
2015 Trader DJ, Simanski S, Kodadek T. A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells. Journal of the American Chemical Society. 137: 6312-9. PMID 25914958 DOI: 10.1021/Jacs.5B02069  0.687
2015 Gao Y, Kodadek T. Direct comparison of linear and macrocyclic compound libraries as a source of protein ligands. Acs Combinatorial Science. 17: 190-5. PMID 25623285 DOI: 10.1021/Co500161C  0.481
2015 Doran TM, Simanski S, Kodadek T. Discovery of native autoantigens via antigen surrogate technology: application to type 1 diabetes. Acs Chemical Biology. 10: 401-12. PMID 25474415 DOI: 10.1021/Cb5007618  0.722
2015 Gao Y, Amar S, Pahwa S, Fields G, Kodadek T. Rapid lead discovery through iterative screening of one bead one compound libraries. Acs Combinatorial Science. 17: 49-59. PMID 25434974 DOI: 10.1021/Co500154E  0.454
2015 Sarma BK, Liu X, Wu H, Gao Y, Kodadek T. Solid phase synthesis of 1,3,4-oxadiazin-5 (6R)-one and 1,3,4-oxadiazol-2-one scaffolds from acyl hydrazides. Organic & Biomolecular Chemistry. 13: 59-63. PMID 25354697 DOI: 10.1039/C4Ob01883D  0.754
2015 Morimoto J, Kodadek T. Synthesis of a large library of macrocyclic peptides containing multiple and diverse N-alkylated residues Molecular Biosystems. 11: 2770-2779. DOI: 10.1039/C5Mb00308C  0.31
2015 Pels K, Kodadek T. Solid-phase synthesis of diverse peptide tertiary amides by reductive amination Acs Combinatorial Science. 17: 152-155. DOI: 10.1021/Acscombsci.5B00007  0.311
2014 Sarkar M, Liu Y, Morimoto J, Peng H, Aquino C, Rader C, Chiorazzi N, Kodadek T. Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates. Chemistry & Biology. 21: 1670-9. PMID 25467125 DOI: 10.1016/J.Chembiol.2014.10.010  0.306
2014 Kodadek T. Chemical tools to monitor and manipulate the adaptive immune system Chemistry and Biology. 21: 1066-1074. PMID 25237855 DOI: 10.1016/J.Chembiol.2014.07.009  0.373
2014 Morimoto J, Sarkar M, Kenrick S, Kodadek T. Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands. Bioconjugate Chemistry. 25: 1479-91. PMID 25073654 DOI: 10.1021/Bc500226J  0.379
2014 Gao Y, Kodadek T. Split-and-pool synthesis and characterization of peptide tertiary amide library Journal of Visualized Experiments. PMID 24998250 DOI: 10.3791/51299  0.509
2014 Suwal S, Kodadek T. Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units Organic and Biomolecular Chemistry. 12: 5831-5834. PMID 24976298 DOI: 10.1039/C4Ob00829D  0.753
2014 Doran TM, Gao Y, Mendes K, Dean S, Simanski S, Kodadek T. Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits. Acs Combinatorial Science. 16: 259-70. PMID 24749624 DOI: 10.1021/Co500030F  0.718
2014 Quan J, Lakhanpal A, Reddy MM, Zaman S, Li QZ, German DC, Olsen NJ, Kodadek T, Karp DR. Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates. Journal of Immunological Methods. 402: 23-34. PMID 24269750 DOI: 10.1016/J.Jim.2013.11.004  0.379
2014 Doran TM, Kodadek T. A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions. Acs Chemical Biology. 9: 339-46. PMID 24245981 DOI: 10.1021/Cb400806R  0.731
2013 Rzuczek SG, Gao Y, Tang ZZ, Thornton CA, Kodadek T, Disney MD. Features of modularly assembled compounds that impart bioactivity against an RNA target. Acs Chemical Biology. 8: 2312-21. PMID 24032410 DOI: 10.1021/Cb400265Y  0.417
2013 Sarkar M, Pascal BD, Steckler C, Aquino C, Micalizio GC, Kodadek T, Chalmers MJ. Decoding split and pool combinatorial libraries with electron-transfer dissociation tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 24: 1026-36. PMID 23636859 DOI: 10.1007/S13361-013-0633-X  0.323
2013 Gao Y, Kodadek T. Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides Chemistry and Biology. 20: 360-369. PMID 23521794 DOI: 10.1016/J.Chembiol.2013.01.013  0.481
2013 Raveendra BL, Wu H, Baccala R, Reddy MM, Schilke J, Bennett JL, Theofilopoulos AN, Kodadek T. Discovery of peptoid ligands for anti-aquaporin 4 antibodies. Chemistry & Biology. 20: 351-9. PMID 23521793 DOI: 10.1016/J.Chembiol.2012.12.009  0.44
2013 Suwal S, Kodadek T. Synthesis of libraries of peptidomimetic compounds containing a 2-oxopiperazine unit in the main chain Organic and Biomolecular Chemistry. 11: 2088-2092. PMID 23440085 DOI: 10.1039/C3Ob27476D  0.783
2012 Sarma BK, Kodadek T. Submonomer synthesis of a hybrid peptoid-azapeptoid library Acs Combinatorial Science. 14: 558-564. PMID 22958123 DOI: 10.1021/Co3000852  0.756
2012 Liu X, Dix M, Speers AE, Bachovchin DA, Zuhl AM, Cravatt BF, Kodadek TJ. Rapid development of a potent photo-triggered inhibitor of the serine hydrolase RBBP9. Chembiochem : a European Journal of Chemical Biology. 13: 2082-93. PMID 22907802 DOI: 10.1002/Cbic.201200445  0.313
2012 Simpson LS, Kodadek T. A Cleavable Scaffold Strategy for the Synthesis of One-Bead One-Compound Cyclic Peptoid Libraries That Can Be Sequenced By Tandem Mass Spectrometry. Tetrahedron Letters. 53: 2341-2344. PMID 22736872 DOI: 10.1016/J.Tetlet.2012.02.112  0.342
2012 Udugamasooriya DG, Kodadek T. On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands. Current Protocols in Chemical Biology. 4: 35-48. PMID 22582145 DOI: 10.1002/9780470559277.Ch110199  0.371
2012 Aditya A, Kodadek T. Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries Acs Combinatorial Science. 14: 164-169. PMID 22320121 DOI: 10.1021/Co200195T  0.374
2012 Aquino C, Sarkar M, Chalmers MJ, Mendes K, Kodadek T, Micalizio GC. A biomimetic polyketide-inspired approach to small-molecule ligand discovery. Nature Chemistry. 4: 99-104. PMID 22270625 DOI: 10.1038/Nchem.1200  0.42
2011 Chen X, Wu J, Luo Y, Liang X, Supnet C, Kim MW, Lotz GP, Yang G, Muchowski PJ, Kodadek T, Bezprozvanny I. Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease. Chemistry & Biology. 18: 1113-25. PMID 21944750 DOI: 10.1016/J.Chembiol.2011.06.010  0.316
2011 Kanta Sarma B, Yousufuddin M, Kodadek T. Acyl hydrazides as peptoid sub-monomers Chemical Communications. 47: 10590-10592. PMID 21892506 DOI: 10.1039/C1Cc12750K  0.322
2011 Cai D, Lee AY, Chiang CM, Kodadek T. Peptoid ligands that bind selectively to phosphoproteins Bioorganic and Medicinal Chemistry Letters. 21: 4960-4964. PMID 21742492 DOI: 10.1016/J.Bmcl.2011.06.011  0.421
2011 Kodadek T. The rise, fall and reinvention of combinatorial chemistry Chemical Communications. 47: 9757-9763. PMID 21701754 DOI: 10.1039/C1Cc12102B  0.391
2011 Reddy MM, Wilson R, Wilson J, Connell S, Gocke A, Hynan L, German D, Kodadek T. Identification of candidate IgG biomarkers for alzheimer's disease via combinatorial library screening Cell. 144: 132-142. PMID 21215375 DOI: 10.1016/J.Cell.2010.11.054  0.359
2010 Lee J, Reddy MM, Kodadek T. Discovery Of An Orexin Receptor Positive Potentiator. Chemical Science (Royal Society of Chemistry : 2010). 1. PMID 24409338 DOI: 10.1039/C0Sc00197J  0.307
2010 Kodadek T. Synthetic receptors with antibody-like binding affinities Current Opinion in Chemical Biology. 14: 713-720. PMID 20674471 DOI: 10.1016/J.Cbpa.2010.07.001  0.391
2010 Kodadek T. Development of antibody surrogates for the treatment of cancers and autoimmune disease Current Opinion in Chemical Biology. 14: 721-727. PMID 20674470 DOI: 10.1016/J.Cbpa.2010.07.002  0.316
2010 Lee J, Udugamasooriya DG, Lim HS, Kodadek T. Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates. Nature Chemical Biology. 6: 258-60. PMID 20228793 DOI: 10.1038/Nchembio.333  0.399
2010 Astle JM, Simpson LS, Huang Y, Reddy MM, Wilson R, Connell S, Wilson J, Kodadek T. Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries. Chemistry & Biology. 17: 38-45. PMID 20142039 DOI: 10.1016/J.Chembiol.2009.12.015  0.419
2009 Kodadek T. Protein binding: Antibody surrogates click into place Nature Chemistry. 1: 183-185. PMID 21378844 DOI: 10.1038/Nchem.228  0.369
2009 Qi X, Astle J, Kodadek T. Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beads Molecular Biosystems. 6: 102-107. PMID 20024071 DOI: 10.1039/B915611A  0.367
2009 Gocke AR, Udugamasooriya DG, Archer CT, Lee J, Kodadek T. Isolation of antagonists of antigen-specific autoimmune T cell proliferation. Chemistry & Biology. 16: 1133-9. PMID 19942136 DOI: 10.1016/J.Chembiol.2009.10.011  0.311
2009 Liu B, Kodadek T. Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides Journal of Medicinal Chemistry. 52: 4604-4612. PMID 19610652 DOI: 10.1021/Jm9002999  0.316
2009 Lim HS, Muralidhar Reddy M, Xiao X, Wilson J, Wilson R, Connell S, Kodadek T. Rapid identification of improved protein ligands using peptoid microarrays Bioorganic and Medicinal Chemistry Letters. 19: 3866-3869. PMID 19380225 DOI: 10.1016/J.Bmcl.2009.03.153  0.406
2009 Simpson LS, Burdine L, Dutta AK, Feranchak AP, Kodadek T. Selective toxin sequestrants for the treatment of bacterial infections. Journal of the American Chemical Society. 131: 5760-2. PMID 19351156 DOI: 10.1021/Ja900852K  0.327
2009 Nalley K, Johnston SA, Kodadek T. Nalley et al. reply Nature. 461: E8. DOI: 10.1038/Nature08407  0.313
2008 Kwon YU, Kodadek T. Encoded combinatorial libraries for the construction of cyclic peptoid microarrays Chemical Communications. 5704-5706. PMID 19009054 DOI: 10.1039/B812735B  0.333
2008 Kodadek T. Proteomes take the electrophilic bait Nature Chemical Biology. 4: 387-388. PMID 18560426 DOI: 10.1038/Nchembio0708-387  0.304
2008 Tan NC, Yu P, Kwon YU, Kodadek T. High-throughput evaluation of relative cell permeability between peptoids and peptides Bioorganic and Medicinal Chemistry. 16: 5853-5861. PMID 18490170 DOI: 10.1016/J.Bmc.2008.04.074  0.303
2008 Udugamasooriya DG, Dineen SP, Brekken RA, Kodadek T. A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity Journal of the American Chemical Society. 130: 5744-5752. PMID 18386897 DOI: 10.1021/Ja711193X  0.359
2008 Shores KS, Udugamasooriya DG, Kodadek T, Knapp DR. Use of peptide analogue diversity library beads for increased depth of proteomic analysis: Application to cerebrospinal fluid Journal of Proteome Research. 7: 1922-1931. PMID 18357977 DOI: 10.1021/Pr7006889  0.331
2008 Marthandan N, Klyza S, Li S, Kwon YU, Kodadek T, Garner HR. Construction and evaluation of an automated light directed protein-detecting microarray synthesizer Ieee Transactions On Nanobioscience. 7: 20-27. PMID 18334452 DOI: 10.1109/Tnb.2008.2000146  0.381
2008 Archer CT, Delahodde A, Gonzalez F, Johnston SA, Kodadek T. Activation domain-dependent monoubiquitylation of Gal4 protein is essential for promoter binding in vivo. The Journal of Biological Chemistry. 283: 12614-23. PMID 18326036 DOI: 10.1074/Jbc.M801050200  0.324
2008 Hanaoka K, Lubag AJ, Castillo-Muzquiz A, Kodadek T, Sherry AD. The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain. Magnetic Resonance Imaging. 26: 608-17. PMID 18234462 DOI: 10.1016/J.Mri.2007.11.002  0.322
2008 Lee J, Yu P, Xiao X, Kodadek T. A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead". Molecular Biosystems. 4: 59-65. PMID 18075676 DOI: 10.1039/B712307H  0.325
2008 Astle JM, Udugamasooriya DG, Smallshaw JE, Kodadek T. A VEGFR2 antagonist and other peptoids evade immune recognition International Journal of Peptide Research and Therapeutics. 14: 223-227. DOI: 10.1007/S10989-008-9136-1  0.336
2007 Lim HS, Cai D, Archer CT, Kodadek T. Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle Journal of the American Chemical Society. 129: 12936-12937. PMID 17929816 DOI: 10.1021/Ja075469+  0.306
2007 Liu B, Archer CT, Burdine L, Gillette TG, Kodadek T. Label transfer chemistry for the characterization of protein-protein interactions Journal of the American Chemical Society. 129: 12348-12349. PMID 17894490 DOI: 10.1021/Ja072904R  0.34
2007 Kwon YU, Kodadek T. Quantitative Comparison of the Relative Cell Permeability of Cyclic and Linear Peptides Chemistry and Biology. 14: 671-677. PMID 17584614 DOI: 10.1016/J.Chembiol.2007.05.006  0.312
2007 Lim HS, Archer CT, Kodadek T. Identification of a peptoid inhibitor of the proteasome 19S regulatory particle Journal of the American Chemical Society. 129: 7750-7751. PMID 17536803 DOI: 10.1021/Ja072027P  0.344
2007 Xiao X, Yu P, Lim HS, Sikder D, Kodadek T. Design and synthesis of a cell-permeable synthetic transcription factor mimic Journal of Combinatorial Chemistry. 9: 592-600. PMID 17530904 DOI: 10.1021/Cc070023A  0.369
2007 Yu P, Liu B, Kodadek T. A convenient, high-throughput assay for measuring the relative cell permeability of synthetic compounds Nature Protocols. 2: 23-30. PMID 17401333 DOI: 10.1038/Nprot.2007.1  0.361
2007 Liu B, Burdine L, Kodadek T. Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins. Journal of the American Chemical Society. 128: 15228-35. PMID 17117875 DOI: 10.1021/Ja065794H  0.318
2006 Alluri P, Liu B, Yu P, Xiao X, Kodadek T. Isolation and characterization of coactivator-binding peptoids from a combinatorial library Molecular Biosystems. 2: 568-579. PMID 17216038 DOI: 10.1039/B608924K  0.378
2005 Archer CT, Burdine L, Kodadek T. Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking. Molecular Biosystems. 1: 366-72. PMID 16881005 DOI: 10.1039/B510019D  0.353
2005 Liu B, Yu P, Alluri PG, Kodadek T. Simple reporter gene-based assays for hairpin poly(amide) conjugate permeability and DNA-binding activity in living cells Molecular Biosystems. 1: 307-317. PMID 16880996 DOI: 10.1039/B511514K  0.343
2005 Kodadek T, Bachhawat-Sikder K. Optimized protocols for the isolation of specific protein-binding peptides or peptoids from combinatorial libraries displayed on beads. Molecular Biosystems. 2: 25-35. PMID 16880920 DOI: 10.1039/B514349G  0.414
2005 Kreishman-Deitrick M, Goley ED, Burdine L, Denison C, Egile C, Li R, Murali N, Kodadek TJ, Welch MD, Rosen MK. NMR analyses of the activation of the Arp2/3 complex by neuronal Wiskott-Aldrich syndrome protein. Biochemistry. 44: 15247-56. PMID 16285728 DOI: 10.1021/Bi051065N  0.309
2005 Reddy MM, Kodadek T. Protein "fingerprinting" in complex mixtures with peptoid microarrays. Proceedings of the National Academy of Sciences of the United States of America. 102: 12672-7. PMID 16123137 DOI: 10.1073/Pnas.0501208102  0.373
2005 Liu B, Alluri PG, Yu P, Kodadek T. A potent transactivation domain mimic with activity in living cells Journal of the American Chemical Society. 127: 8254-8255. PMID 15941237 DOI: 10.1021/Ja0515295  0.327
2005 Yu P, Liu B, Kodadek T. A high-throughput assay for assessing the cell permeability of combinatorial libraries. Nature Biotechnology. 23: 746-51. PMID 15908941 DOI: 10.1038/Nbt1099  0.371
2005 Kodadek T, Duroux-Richard I, Bonnafous JC. Techniques: Oxidative cross-linking as an emergent tool for the analysis of receptor-mediated signalling events. Trends in Pharmacological Sciences. 26: 210-7. PMID 15808346 DOI: 10.1016/J.Tips.2005.02.010  0.313
2005 Lin HJ, Kodadek T. Photo-induced oxidative cross-linking as a method to evaluate the specificity of protein-ligand interactions Journal of Peptide Research. 65: 221-228. PMID 15705166 DOI: 10.1111/J.1399-3011.2005.00227.X  0.411
2005 Reddy MM, Bachhawat-Sikder K, Kodadek T. Transformation of low-affinity lead compounds into high-affinity protein capture agents. Chemistry & Biology. 11: 1127-37. PMID 15324814 DOI: 10.1016/J.Chembiol.2004.05.013  0.425
2005 Troitskaya LA, Kodadek T. Peptides as modulators of enzymes and regulatory proteins. Methods (San Diego, Calif.). 32: 406-15. PMID 15003603 DOI: 10.1016/J.Ymeth.2003.10.008  0.344
2004 Smith AH, Vrtis JM, Kodadek T. The potential of protein-detecting microarrays for clinical diagnostics. Advances in Clinical Chemistry. 38: 217-38. PMID 15521193 DOI: 10.1016/S0065-2423(04)38007-8  0.341
2004 Kodadek T, Reddy MM, Olivos HJ, Bachhawat-Sikder K, Alluri PG. Synthetic molecules as antibody replacements Accounts of Chemical Research. 37: 711-718. PMID 15379586 DOI: 10.1021/Ar030145L  0.402
2004 Burdine L, Gillette TG, Lin HJ, Kodadek T. Periodate-triggered cross-linking of DOPA-containing peptide-protein complexes. Journal of the American Chemical Society. 126: 11442-3. PMID 15366882 DOI: 10.1021/Ja045982C  0.362
2004 Li S, Bowerman D, Marthandan N, Klyza S, Luebke KJ, Garner HR, Kodadek T. Photolithographic synthesis of peptoids. Journal of the American Chemical Society. 126: 4088-9. PMID 15053581 DOI: 10.1021/Ja039565W  0.332
2004 Naffin JL, Han Y, Olivos HJ, Reddy MM, Sun T, Kodadek T. Immobilized peptides as high-affinity capture agents for self-associating proteins. Chemistry & Biology. 10: 251-9. PMID 12670539 DOI: 10.1016/S1074-5521(03)00049-8  0.391
2003 Amini F, Denison C, Lin HJ, Kuo L, Kodadek T. Using oxidative crosslinking and proximity labeling to quantitatively characterize protein-protein and protein-Peptide complexes. Chemistry & Biology. 10: 1115-27. PMID 14652079 DOI: 10.1016/J.Chembiol.2003.11.001  0.333
2003 Alluri PG, Reddy MM, Bachhawat-Sikder K, Olivos HJ, Kodadek T. Isolation of Protein Ligands from Large Peptoid Libraries Journal of the American Chemical Society. 125: 13995-14004. PMID 14611236 DOI: 10.1021/Ja036417X  0.411
2003 Liu B, Han Y, Ferdous A, Corey DR, Kodadek T. Transcription activation by a PNA-peptide chimera in a mammalian cell extract. Chemistry & Biology. 10: 909-16. PMID 14583257 DOI: 10.1016/J.Chembiol.2003.09.008  0.325
2003 Bachhawat-Sikder K, Kodadek T. Mixed-element capture agents: a simple strategy for the construction of synthetic, high-affinity protein capture ligands. Journal of the American Chemical Society. 125: 9550-1. PMID 12903996 DOI: 10.1021/Ja034912N  0.368
2002 Sun L, Kodadek T. Removal of impurities from transcription factor preparations that alter their DNA-binding properties. Nucleic Acids Research. 30: e88. PMID 12177316 DOI: 10.1093/Nar/Gnf087  0.319
2002 Kodadek T. Development of protein-detecting microarrays and related devices. Trends in Biochemical Sciences. 27: 295-300. PMID 12069789 DOI: 10.1016/S0968-0004(02)02105-9  0.35
2002 De León-Rodríguez LM, Ortiz A, Weiner AL, Zhang S, Kovacs Z, Kodadek T, Sherry AD. Magnetic resonance imaging detects a specific peptide-protein binding event. Journal of the American Chemical Society. 124: 3514-5. PMID 11929234 DOI: 10.1021/Ja025511V  0.331
2002 Amini F, Kodadek T, Brown KC. Protein Affinity Labeling Mediated by Genetically Encoded Peptide Tags Angewandte Chemie. 114: 366-369. DOI: 10.1002/1521-3757(20020118)114:2<366::Aid-Ange366>3.0.Co;2-6  0.3
2001 Chang C, Gonzalez F, Rothermel B, Sun L, Johnston SA, Kodadek T. The Gal4 activation domain binds Sug2 protein, a proteasome component, in vivo and in vitro. The Journal of Biological Chemistry. 276: 30956-63. PMID 11418596 DOI: 10.1074/Jbc.M102254200  0.337
2001 Zhang Z, Ly T, Kodadek T. An inhibitor of sequence-specific proteolysis that targets the substrate rather than the enzyme Chemistry and Biology. 8: 391-397. PMID 11325594 DOI: 10.1016/S1074-5521(01)00021-7  0.316
2001 Kodadek T. Protein microarrays: prospects and problems. Chemistry & Biology. 8: 105-15. PMID 11251285 DOI: 10.1016/S1074-5521(00)90067-X  0.31
2001 Xie Y, Sun L, Kodadek T. TATA-binding protein and the Gal4 transactivator do not bind to promoters cooperatively. The Journal of Biological Chemistry. 275: 40797-803. PMID 11006288 DOI: 10.1074/Jbc.M007019200  0.342
2000 Xie Y, Denison C, Yang SH, Fancy DA, Kodadek T. Biochemical characterization of the TATA-binding protein-Gal4 activation domain complex. The Journal of Biological Chemistry. 275: 31914-20. PMID 10931832 DOI: 10.1074/Jbc.M003760200  0.343
2000 Zhu W, Williams RS, Kodadek T. A CDC6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor. The Journal of Biological Chemistry. 275: 32098-105. PMID 10896933 DOI: 10.1074/Jbc.M001560200  0.404
2000 Han Y, Kodadek T. Peptides selected to bind the Gal80 repressor are potent transcriptional activation domains in yeast. The Journal of Biological Chemistry. 275: 14979-84. PMID 10809742 DOI: 10.1074/Jbc.275.20.14979  0.341
2000 Zhang Z, Zhu W, Kodadek T. Selection and application of peptide-binding peptides. Nature Biotechnology. 18: 71-4. PMID 10625395 DOI: 10.1038/71951  0.302
1999 Patikoglou GA, Kim JL, Sun L, Yang SH, Kodadek T, Burley SK. TATA element recognition by the TATA box-binding protein has been conserved throughout evolution. Genes & Development. 13: 3217-30. PMID 10617571 DOI: 10.1101/Gad.13.24.3217  0.31
1999 Zhang Z, Murphy A, Hu JC, Kodadek T. Genetic selection of short peptides that support protein oligomerization in vivo. Current Biology : Cb. 9: 417-20. PMID 10226028 DOI: 10.1016/S0960-9822(99)80188-2  0.341
1998 Vashee S, Willie J, Kodadek T. Synergistic activation of transcription by physiologically unrelated transcription factors through cooperative DNA-binding. Biochemical and Biophysical Research Communications. 247: 530-5. PMID 9642164 DOI: 10.1006/Bbrc.1998.8820  0.317
1998 Fancy DA, Kodadek T. A critical role for tyrosine residues in His6Ni-mediated protein cross-linking. Biochemical and Biophysical Research Communications. 247: 420-6. PMID 9642143 DOI: 10.1006/Bbrc.1998.8558  0.309
1998 Vashee S, Melcher K, Ding WV, Johnston SA, Kodadek T. Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein-protein interactions. Current Biology : Cb. 8: 452-8. PMID 9550700 DOI: 10.1016/S0960-9822(98)70179-4  0.335
1997 Jiang H, Salinas F, Kodadek T. The gene 32 single-stranded DNA-binding protein is not bound stably to the phage T4 presynaptic filament. Biochemical and Biophysical Research Communications. 231: 600-5. PMID 9070854 DOI: 10.1006/Bbrc.1997.6160  0.31
1997 Jiang H, Xie Y, Houston P, Stemke-Hale K, Mortensen UH, Rothstein R, Kodadek T. Direct association between the yeast Rad51 and Rad54 recombination proteins. The Journal of Biological Chemistry. 271: 33181-6. PMID 8969173 DOI: 10.1074/Jbc.271.52.33181  0.31
1997 Fancy DA, Melcher K, Johnston SA, Kodadek T. New chemistry for the study of multiprotein complexes: the six-histidine tag as a receptor for a protein crosslinking reagent. Chemistry & Biology. 3: 551-9. PMID 8807887 DOI: 10.1016/S1074-5521(96)90146-5  0.346
1997 Fancy DA, Kodadek T. Site-directed oxidative protein crosslinking Tetrahedron. 53: 11953-11960. DOI: 10.1016/S0040-4020(97)00708-4  0.326
1995 Salinas F, Jiang H, Kodadek T. Homology dependence of UvsX protein-catalyzed joint molecule formation. The Journal of Biological Chemistry. 270: 5181-6. PMID 7890628 DOI: 10.1074/Jbc.270.10.5181  0.324
1995 Salinas F, Kodadek T. Strand exchange through a DNA-protein complex requires a DNA helicase. Biochemical and Biophysical Research Communications. 205: 1004-9. PMID 7802625 DOI: 10.1006/Bbrc.1994.2766  0.309
1995 Brown KC, Yang SH, Kodadek T. Highly specific oxidative cross-linking of proteins mediated by a nickel-peptide complex. Biochemistry. 34: 4733-9. PMID 7718579 DOI: 10.1021/Bi00014A030  0.317
1995 Xu HE, Kodadek T, Johnston SA. A single GAL4 dimer can maximally activate transcription under physiological conditions. Proceedings of the National Academy of Sciences of the United States of America. 92: 7677-80. PMID 7644476 DOI: 10.1073/Pnas.92.17.7677  0.307
1995 Vashee S, Kodadek T. The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo. Proceedings of the National Academy of Sciences of the United States of America. 92: 10683-7. PMID 7479865 DOI: 10.1073/Pnas.92.23.10683  0.314
1995 Sessler JL, Lisowski J, Boudreaux KA, Lynch V, Barry J, Kodadek TJ. Synthesis and characterization of diaryl sapphyrins prepared under Lindsey-type conditions The Journal of Organic Chemistry. 60: 5975-5978. DOI: 10.1021/Jo00123A043  0.403
1995 Wolf JR, Hamaker CG, Djukic J, Kodadek T, Woo LK. Shape and stereoselective cyclopropanation of alkenes catalyzed by iron porphyrins. Journal of the American Chemical Society. 117: 9194-9199. DOI: 10.1021/Ja00141A011  0.553
1995 Sessler JL, Lisowski J, Boudreaux KA, Lynch V, Barry J, Kodadek TJ. Synthesis and characterization of Diaryl Sapphyrins prepared under Lindsey-type conditions Journal of Organic Chemistry. 60: 5975-5978.  0.315
1994 Maine IP, Kodadek T. Inhibition of the DNA unwinding and ATP hydrolysis activities of the bacteriophage T4 DDA helicase by a sequence specific DNA-protein complex. Biochemical and Biophysical Research Communications. 198: 1070-7. PMID 8117263 DOI: 10.1006/Bbrc.1994.1152  0.31
1991 Hansen A, Van Hoy M, Kodadek T. Spectroscopic studies of the DNA binding site of the GAL4 "zinc finger" protein. Biochemical and Biophysical Research Communications. 175: 492-9. PMID 2018497 DOI: 10.1016/0006-291X(91)91591-Y  0.318
1990 Kodadek T. Functional interactions between phage T4 and E. coli DNA-binding proteins during the presynapsis phase of homologous recombination. Biochemical and Biophysical Research Communications. 172: 804-10. PMID 2241970 DOI: 10.1016/0006-291X(90)90746-A  0.333
1987 Kodadek T, Alberts BM. Stimulation of protein-directed strand exchange by a DNA helicase. Nature. 326: 312-4. PMID 2950327 DOI: 10.1038/326312A0  0.537
1986 Collman JP, Kodadek T, Brauman JI. Oxygenation of styrene by cytochrome P-450 model systems: A mechanistic study Journal of the American Chemical Society®. 108: 2588-2594. DOI: 10.1002/Chin.198637118  0.546
1986 COLLMAN JP, KODADEK T, BRAUMAN JI. ChemInform Abstract: Oxygenation of Styrene by Cytochrome P-450 Model Systems: A Mechanistic Study. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198637118  0.505
1985 Collman JP, Brauman JI, Meunier B, Hayashi T, Kodadek T, Raybuck SA. Epoxidation of olefins by cytochrome P-450 model compounds: kinetics and stereochemistry of oxygen atom transfer and origin of shape selectivity Journal of the American Chemical Society. 107: 2000-2005. DOI: 10.1021/Ja00293A034  0.572
1985 COLLMAN JP, KODADEK T, RAYBUCK SA, BRAUMAN JI, PAPAZIAN LM. ChemInform Abstract: Mechanism of Oxygen Atom Transfer from High Valent Iron Porphyrins to Olefins: Implications to the Biological Epoxidation of Olefins by Cytochrome P-450. Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198544103  0.519
1985 Kodadek T, Raybuck SA, Collman JP, Brauman JI, Papazian LM. Mechanism of oxygen atom transfer from high valent iron porphyrins to olefins: implications to the biological epoxidation of olefins by cytochrome P-450 Journal of the American Chemical Society. 107: 4343-4345. DOI: 10.1002/Chin.198544103  0.56
1985 COLLMAN JP, BRAUMAN JI, MEUNIER B, HAYASHI T, KODADEK T, RAYBUCK SA. ChemInform Abstract: EPOXIDATION OF OLEFINS BY CYTOCHROME P-450 MODEL COMPOUNDS: KINETICS AND STEREOCHEMISTRY OF OXYGEN ATOM TRANSFER AND ORIGIN OF SHAPE SELECTIVITY Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198533140  0.532
1984 Collman JP, Brauman JI, Meunier B, Raybuck SA, Kodadek T. Epoxidation of olefins by cytochrome P-450 model compounds: mechanism of oxygen atom transfer. Proceedings of the National Academy of Sciences of the United States of America. 81: 3245-8. PMID 6587349 DOI: 10.1073/Pnas.81.10.3245  0.582
1983 Collman JP, Kodadek T, Raybuck SA, Meunier B. Oxygenation of hydrocarbons by cytochrome P-450 model compounds: modification of reactivity by axial ligands. Proceedings of the National Academy of Sciences of the United States of America. 80: 7039-41. PMID 6580626 DOI: 10.1073/Pnas.80.22.7039  0.484
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