Vinee Purohit - Publications

Affiliations: 
2019- Harvard University and Broad Institute 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Tang R, Acharya N, Subramanian A, Purohit V, Tabaka M, Hou Y, He D, Dixon KO, Lambden C, Xia J, Rozenblatt-Rosen O, Sobel RA, Wang C, Regev A, Anderson AC, et al. Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function. Science Immunology. 7: eabm0631. PMID 35275752 DOI: 10.1126/sciimmunol.abm0631  0.479
2022 Purohit V, Wagner A, Yosef N, Kuchroo VK. Systems-based approaches to study immunometabolism. Cellular & Molecular Immunology. 19: 409-420. PMID 35121805 DOI: 10.1038/s41423-021-00783-9  0.417
2021 Purohit V, Wang L, Yang H, Li J, Ney GM, Gumkowski ER, Vaidya AJ, Wang A, Bhardwaj A, Zhao E, Dolgalev I, Zamperone A, Abel EV, Magliano MPD, Crawford HC, et al. ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer. Genes & Development. PMID 33446568 DOI: 10.1101/gad.344184.120  0.639
2020 Little AC, Kovalenko I, Goo LE, Hong HS, Kerk SA, Yates JA, Purohit V, Lombard DB, Merajver SD, Lyssiotis CA. High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions. Communications Biology. 3: 271. PMID 32472013 DOI: 10.1038/s42003-020-0988-z  0.527
2020 Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, et al. Cysteine depletion induces pancreatic tumor ferroptosis in mice. Science (New York, N.Y.). 368: 85-89. PMID 32241947 DOI: 10.1126/Science.Aaw9872  0.568
2019 Purohit V, Simeone DM, Lyssiotis CA. Metabolic Regulation of Redox Balance in Cancer. Cancers. 11. PMID 31288436 DOI: 10.3390/Cancers11070955  0.65
2019 Wang L, Yang H, Zamperone A, Diolaiti D, Palmbos PL, Abel EV, Purohit V, Dolgalev I, Rhim AD, Ljungman M, Hadju CH, Halbrook CJ, Bar-Sagi D, di Magliano MP, Crawford HC, et al. ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis. Genes & Development. PMID 31048544 DOI: 10.1101/Gad.323303.118  0.671
2018 Gebregiworgis T, Bhinderwala F, Purohit V, Chaika NV, Singh PK, Powers R. Insights into gemcitabine resistance and the potential for therapeutic monitoring. Metabolomics : Official Journal of the Metabolomic Society. 14: 156. PMID 30830412 DOI: 10.1007/S11306-018-1452-7  0.369
2017 Shukla SK, Purohit V, Mehla K, Gunda V, Chaika NV, Vernucci E, King RJ, Abrego J, Goode GD, Dasgupta A, Illies AL, Gebregiworgis T, Dai B, Augustine JJ, Murthy D, et al. MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer. Cancer Cell. 32: 392. PMID 28898700 DOI: 10.1016/J.Ccell.2017.08.008  0.653
2017 Gebregiworgis T, Purohit V, Shukla SK, Tadros S, Chaika NV, Abrego J, Mulder SE, Gunda V, Singh PK, Powers R. Glucose limitation alters glutamine metabolism in MUC1 overexpressing pancreatic cancer cells. Journal of Proteome Research. PMID 28809118 DOI: 10.1021/Acs.Jproteome.7B00246  0.412
2017 Shukla SK, Purohit V, Mehla K, Gunda V, Chaika NV, Vernucci E, King RJ, Abrego J, Goode GD, Dasgupta A, Illies AL, Gebregiworgis T, Dai B, Augustine JJ, Murthy D, et al. MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer. Cancer Cell. 32: 71-87.e7. PMID 28697344 DOI: 10.1016/J.Ccell.2017.06.004  0.693
2017 Goode G, Gunda V, Chaika NV, Purohit V, Yu F, Singh PK. Correction: MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer. Plos One. 12: e0179098. PMID 28570622 DOI: 10.1371/Journal.Pone.0179098  0.301
2017 Goode G, Gunda V, Chaika NV, Purohit V, Yu F, Singh PK. MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer. Plos One. 12: e0176820. PMID 28464016 DOI: 10.1371/Journal.Pone.0176820  0.454
2016 Divakar SA, Reddy MVR, Cosenza SC, Baker SJ, Purohit V, Gunda V, Singh PK, Reddy EP. Abstract 3029: Dual targeting of ARK5 and CDK4 pathways with ON 123300 as a therapeutic strategy for colorectal carcinoma Cancer Research. 76: 3029-3029. DOI: 10.1158/1538-7445.Am2016-3029  0.461
2016 Goode GD, Chaika N, Purohit V, Gunda V, Singh P. Abstract 1152: MUC1: A metabolic regulator in triple-negative breast cancer Cancer Research. 76: 1152-1152. DOI: 10.1158/1538-7445.Am2016-1152  0.487
2015 Yang S, Zhang L, Purohit V, Shukla SK, Chen X, Yu F, Fu K, Chen Y, Solheim J, Singh PK, Song W, Dong J. Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3. Oncotarget. PMID 26440309 DOI: 10.18632/Oncotarget.5935  0.488
2014 Shukla SK, Gebregiworgis T, Purohit V, Chaika NV, Gunda V, Radhakrishnan P, Mehla K, Pipinos II, Powers R, Yu F, Singh PK. Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia. Cancer & Metabolism. 2: 18. PMID 25228990 DOI: 10.1186/2049-3002-2-18  0.488
2013 Purohit V, Chaika NV, Gebregiworgis T, Radhakrishnan P, Zhang B, Mehla K, Yu F, Johnson KR, Powers R, Hollingsworth MA, Singh PK. Abstract 5391: MUC1 and HIF-1α signaling interactions modulate glucose flux in pancreatic cancer. Cancer Research. 73: 5391-5391. DOI: 10.1158/1538-7445.Am2013-5391  0.497
2013 Zou Y, Howell GM, Brattain LE, Wang J, Purohit V, Singh P, Brattain MG. Abstract 1005: Ron monoclonal antibody IMC-RON8 sensitizes pancreatic cancer to histone deacetylase inhibitors. Cancer Research. 73: 1005-1005. DOI: 10.1158/1538-7445.Am2013-1005  0.356
2012 Chaika NV, Gebregiworgis T, Lewallen ME, Purohit V, Radhakrishnan P, Liu X, Zhang B, Mehla K, Brown RB, Caffrey T, Yu F, Johnson KR, Powers R, Hollingsworth MA, Singh PK. MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 13787-92. PMID 22869720 DOI: 10.1073/Pnas.1203339109  0.536
2012 Torres MP, Rachagani S, Purohit V, Pandey P, Joshi S, Moore ED, Johansson SL, Singh PK, Ganti AK, Batra SK. Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism. Cancer Letters. 323: 29-40. PMID 22475682 DOI: 10.1016/J.Canlet.2012.03.031  0.531
2012 Chaika NV, Yu F, Purohit V, Mehla K, Lazenby AJ, DiMaio D, Anderson JM, Yeh JJ, Johnson KR, Hollingsworth MA, Singh PK. Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma. Plos One. 7: e32996. PMID 22412968 DOI: 10.1371/Journal.Pone.0032996  0.544
2012 Purohit V, Chaika NV, Gebregiworgis TG, Powers R, Johnson KR, Hollingsworth MA, Singh PK. Abstract 5152: Targeting HIF1α-mediated metabolic alterations in pancreatic cancer Cancer Research. 72: 5152-5152. DOI: 10.1158/1538-7445.Am2012-5152  0.538
2011 Singh PK, Purohit V, Chaika N, Johnson KR, Hollingsworth MA. Abstract 991: Regulation of glucose metabolism by HIF in pancreatic cancer Cellular and Molecular Biology. 71: 991-991. DOI: 10.1158/1538-7445.Am2011-991  0.484
Show low-probability matches.