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Yvonne Y. Chen, Ph.D. - Publications

Affiliations: 
Chemical Engineering University of California, Los Angeles, Los Angeles, CA 
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cabera A, Edelstein HI, Glykofrydis F, Love KS, Palacios S, Tycko J, Zhang M, Lensch S, Shields CE, Livingston M, Weiss R, Zhao H, Haynes KA, Morsut L, Chen YY, et al. The sound of silence: Transgene silencing in mammalian cell engineering. Cell Systems. 13: 950-973. PMID 36549273 DOI: 10.1016/j.cels.2022.11.005  0.547
2020 Li JH, Chen YY. A Fresh Approach to Targeting Aging Cells: CAR-T Cells Enhance Senolytic Specificity. Cell Stem Cell. 27: 192-194. PMID 32763179 DOI: 10.1016/J.Stem.2020.07.010  0.358
2020 Jayaraman J, Mellody MP, Hou AJ, Desai RP, Fung AW, Pham AHT, Chen YY, Zhao W. CAR-T design: Elements and their synergistic function. Ebiomedicine. 58: 102931. PMID 32739874 DOI: 10.1016/J.Ebiom.2020.102931  0.401
2020 Hong M, Clubb JD, Chen YY. Engineering CAR-T Cells for Next-Generation Cancer Therapy. Cancer Cell. PMID 32735779 DOI: 10.1016/J.Ccell.2020.07.005  0.383
2020 Zah E, Nam E, Bhuvan V, Tran U, Ji BY, Gosliner SB, Wang X, Brown CE, Chen YY. Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma. Nature Communications. 11: 2283. PMID 32385241 DOI: 10.1038/S41467-020-16160-5  0.378
2020 Chang ZL, Hou AJ, Chen YY. Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands. Nature Protocols. PMID 32103205 DOI: 10.1038/S41596-020-0294-8  0.389
2019 Chen YY, Van Deventer JA. Editorial overview: Pharmaceutical biotechnology: new frontiers in protein, gene, and cell therapies. Current Opinion in Biotechnology. PMID 31690473 DOI: 10.1016/J.Copbio.2019.09.022  0.306
2019 Chen LC, Chen YY. Outsmarting and outmuscling cancer cells with synthetic and systems immunology. Current Opinion in Biotechnology. 60: 111-118. PMID 30822698 DOI: 10.1016/J.Copbio.2019.01.016  0.387
2018 Chen YY. Increasing T Cell Versatility with SUPRA CARs. Cell. 173: 1316-1317. PMID 29856949 DOI: 10.1016/J.Cell.2018.05.030  0.356
2018 Chang ZL, Lorenzini MH, Chen X, Tran U, Bangayan NJ, Chen YY. Rewiring T-cell responses to soluble factors with chimeric antigen receptors. Nature Chemical Biology. PMID 29377003 DOI: 10.1038/Nchembio.2565  0.354
2018 Chang ZL, Lorenzini MH, Chen YY. Abstract IA08: Engineering T cells to resist and convert immunosuppressive tumor microenvironments Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-Ia08  0.325
2017 Wong RS, Chen YY, Smolke CD. Regulation of T cell proliferation with drug-responsive microRNA switches. Nucleic Acids Research. PMID 29244152 DOI: 10.1093/Nar/Gkx1228  0.701
2017 Ho P, Chen YY. Mammalian synthetic biology in the age of genome editing and personalized medicine. Current Opinion in Chemical Biology. 40: 57-64. PMID 28628856 DOI: 10.1016/J.Cbpa.2017.06.003  0.346
2017 Ho P, Ede C, Chen YY. Modularly Constructed Synthetic Granzyme B Molecule Enables Interrogation of Intracellular Proteases for Targeted Cytotoxicity. Acs Synthetic Biology. PMID 28510446 DOI: 10.1021/Acssynbio.6B00392  0.395
2017 Chang ZL, Chen YY. CARs: Synthetic Immunoreceptors for Cancer Therapy and Beyond. Trends in Molecular Medicine. PMID 28416139 DOI: 10.1016/J.Molmed.2017.03.002  0.391
2017 Zah E, Lin M, Jensen MC, Silva-Benedict A, Chen YY. Abstract IA12: Combating antigen escape with CD19/CD20 bispecific CAR-T cell therapy Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-Ia12  0.32
2016 Zah E, Lin MY, Silva-Benedict A, Jensen MC, Chen YY. T cells expressing CD19/CD20 bi-specific chimeric antigen receptors prevent antigen escape by malignant B cells. Cancer Immunology Research. PMID 27059623 DOI: 10.1158/2326-6066.Cir-15-0231  0.323
2016 Ede C, Chen X, Lin MY, Chen YY. Quantitative Analyses of Core Promoters Enable Precise Engineering of Regulated Gene Expression in Mammalian Cells. Acs Synthetic Biology. PMID 26883397 DOI: 10.1021/Acssynbio.5B00266  0.36
2016 Chang ZL, Silver PA, Chen YY. Abstract B022: Functional bifurcation in T cells expressing chimeric antigen receptors Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B022  0.368
2015 Liang JH, Gao R, Xia Y, Gale RP, Chen RZ, Yang YQ, Wang L, Qu XY, Qiu HR, Cao L, Hong M, Wang R, Wang Y, Fan L, Chen YY, et al. Prognostic impact of Epstein-Barr Virus (EBV)-DNA copy number at diagnosis in chronic lymphocytic leukemia. Oncotarget. PMID 26539641 DOI: 10.18632/oncotarget.6281  0.365
2015 Chen YY. Efficient Gene Editing in Primary Human T Cells. Trends in Immunology. PMID 26440702 DOI: 10.1016/J.It.2015.09.001  0.376
2015 Chang ZL, Silver PA, Chen YY. Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptors. Journal of Translational Medicine. 13: 161. PMID 25990251 DOI: 10.1186/S12967-015-0519-8  0.363
2013 Wei KY, Chen YY, Smolke CD. A yeast-based rapid prototype platform for gene control elements in mammalian cells. Biotechnology and Bioengineering. 110: 1201-10. PMID 23184812 DOI: 10.1002/Bit.24792  0.667
2012 Chen YY, Galloway KE, Smolke CD. Synthetic biology: advancing biological frontiers by building synthetic systems. Genome Biology. 13: 240. PMID 22348749 DOI: 10.1186/Gb-2012-13-2-240  0.653
2011 Chen YY, Smolke CD. From DNA to targeted therapeutics: bringing synthetic biology to the clinic. Science Translational Medicine. 3: 106ps42. PMID 22030748 DOI: 10.1126/Scitranslmed.3002944  0.606
2011 Beisel CL, Chen YY, Culler SJ, Hoff KG, Smolke CD. Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing. Nucleic Acids Research. 39: 2981-94. PMID 21149259 DOI: 10.1093/Nar/Gkq954  0.646
2010 Chen YY, Jensen MC, Smolke CD. Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems. Proceedings of the National Academy of Sciences of the United States of America. 107: 8531-6. PMID 20421500 DOI: 10.1073/Pnas.1001721107  0.644
2008 Chen YY, Brown CE, Jensen MC, Smolke CD. T cell proliferation control with small molecule-responsive RNA-based regulatory systems Aiche Annual Meeting, Conference Proceedings.  0.591
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