Scott Rothbart - Publications

2010-2015 Head, Laboratory of Chromatin and Epigenetic Regulation The Van Andel Institute 

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Colino-Sanguino Y, Cornett EM, Moulder D, Smith GC, Hrit J, Cordeiro-Spinetti E, Vaughan RM, Krajewski K, Rothbart SB, Clark SJ, Valdés-Mora F. A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation. Iscience. PMID 31727574 DOI: 10.1016/j.isci.2019.10.053  0.56
2019 Zhang Y, Jang Y, Lee JE, Ahn J, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, et al. Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nature Communications. 10: 2314. PMID 31127101 DOI: 10.1038/s41467-019-10324-8  0.8
2018 Cornett EM, Dickson BM, Krajewski K, Spellmon N, Umstead A, Vaughan RM, Shaw KM, Versluis PP, Cowles MW, Brunzelle J, Yang Z, Vega IE, Sun ZW, Rothbart SB. A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity. Science Advances. 4: eaav2623. PMID 30498785 DOI: 10.1126/sciadv.aav2623  0.56
2018 Shah RN, Grzybowski AT, Cornett EM, Johnstone AL, Dickson BM, Boone BA, Cheek MA, Cowles MW, Maryanski D, Meiners MJ, Tiedemann RL, Vaughan RM, Arora N, Sun ZW, Rothbart SB, et al. Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies. Molecular Cell. PMID 30244833 DOI: 10.1016/j.molcel.2018.08.015  0.32
2017 Veland N, Hardikar S, Zhong Y, Gayatri S, Dan J, Strahl BD, Rothbart SB, Bedford MT, Chen T. The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer. Cell Reports. 21: 3390-3397. PMID 29262320 DOI: 10.1016/j.celrep.2017.11.082  0.8
2017 Shanle EK, Shinsky SA, Bridgers JB, Bae N, Sagum C, Krajewski K, Rothbart SB, Bedford MT, Strahl BD. Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions. Epigenetics & Chromatin. 10: 12. PMID 28293301 DOI: 10.1186/s13072-017-0117-5  0.8
2016 Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto AL, Yang Y, Ntziachristos P, Rothbart S, Buckley S, Dolgalev I, Stadtfeld M, Strahl BD, Dynlacht BD, Tsirigos A, Aifantis I. Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a. Nature Cell Biology. PMID 27749823 DOI: 10.1038/ncb3424  0.8
2016 Andrews FH, Tong Q, Sullivan KD, Cornett EM, Zhang Y, Ali M, Ahn J, Pandey A, Guo AH, Strahl BD, Costello JC, Espinosa JM, Rothbart SB, Kutateladze TG. Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase. Cell Reports. 16: 3195-207. PMID 27653685 DOI: 10.1016/j.celrep.2016.08.050  0.48
2016 Harrison JS, Cornett EM, Goldfarb D, DaRosa PA, Li ZM, Yan F, Dickson BM, Guo AH, Cantu DV, Kaustov L, Brown PJ, Arrowsmith CH, Erie DA, Major MB, Klevit RE, ... ... Rothbart SB, et al. Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1. Elife. 5. PMID 27595565 DOI: 10.7554/eLife.17101  0.8
2015 Cliffe AR, Arbuckle JH, Vogel JL, Geden MJ, Rothbart SB, Cusack CL, Strahl BD, Kristie TM, Deshmukh M. Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation. Cell Host & Microbe. 18: 649-58. PMID 26651941 DOI: 10.1016/j.chom.2015.11.007  0.48
2015 Agarwal S, Bell CM, Rothbart SB, Moran RG. AMPK control of mTORC1 is p53- and TSC2-independent in pemetrexed-treated carcinoma cells. The Journal of Biological Chemistry. PMID 26391395 DOI: 10.1074/jbc.M115.665133  0.48
2015 Simon JM, Parker JS, Liu F, Rothbart SB, Ait-Si-Ali S, Strahl BD, Jin J, Davis IJ, Mosley AL, Pattenden SG. A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin. The Journal of Biological Chemistry. 290: 26088-102. PMID 26338712 DOI: 10.1074/jbc.M115.654459  0.48
2015 Zhang ZM, Rothbart SB, Allison DF, Cai Q, Harrison JS, Li L, Wang Y, Strahl BD, Wang GG, Song J. An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1. Cell Reports. 12: 1400-6. PMID 26299963 DOI: 10.1016/j.celrep.2015.07.046  0.48
2015 Ali M, Daze KD, Strongin DE, Rothbart SB, Rincon-Arano H, Allen HF, Li J, Strahl BD, Hof F, Kutateladze TG. Molecular insight into inhibition of the methylated histone-plant homeodomain complexes by calixarenes. The Journal of Biological Chemistry. PMID 26229108 DOI: 10.1074/jbc.M115.669333  0.48
2015 Rothbart SB, Dickson BM, Raab JR, Grzybowski AT, Krajewski K, Guo AH, Shanle EK, Josefowicz SZ, Fuchs SM, Allis CD, Magnuson TR, Ruthenburg AJ, Strahl BD. An Interactive Database for the Assessment of Histone Antibody Specificity. Molecular Cell. 59: 502-11. PMID 26212453 DOI: 10.1016/j.molcel.2015.06.022  0.8
2015 Rothbart SB, Dickson BM, Strahl BD. From histones to ribosomes: a chromatin regulator tangoes with translation. Cancer Discovery. 5: 228-30. PMID 25749972 DOI: 10.1158/2159-8290.CD-15-0073  0.48
2015 Tong Q, Mazur SJ, Rincon-Arano H, Rothbart SB, Kuznetsov DM, Cui G, Liu WH, Gete Y, Klein BJ, Jenkins L, Mer G, Kutateladze AG, Strahl BD, Groudine M, Appella E, et al. An acetyl-methyl switch drives a conformational change in p53. Structure (London, England : 1993). 23: 322-31. PMID 25651062 DOI: 10.1016/j.str.2014.12.010  0.48
2015 Perfetti MT, Baughman BM, Dickson BM, Mu Y, Cui G, Mader P, Dong A, Norris JL, Rothbart SB, Strahl BD, Brown PJ, Janzen WP, Arrowsmith CH, Mer G, McBride KM, et al. Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. Acs Chemical Biology. 10: 1072-81. PMID 25590533 DOI: 10.1021/cb500956g  0.48
2015 Tong Q, Cui G, Botuyan MV, Rothbart SB, Hayashi R, Musselman CA, Singh N, Appella E, Strahl BD, Mer G, Kutateladze TG. Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1. Structure (London, England : 1993). 23: 312-21. PMID 25579814 DOI: 10.1016/j.str.2014.11.013  0.48
2014 Shanle EK, Rothbart SB, Strahl BD. Chromatin biochemistry enters the next generation of code 'seq-ing'. Nature Methods. 11: 799-800. PMID 25075906 DOI: 10.1038/nmeth.3044  0.8
2014 Greer EL, Beese-Sims SE, Brookes E, Spadafora R, Zhu Y, Rothbart SB, Aristizábal-Corrales D, Chen S, Badeaux AI, Jin Q, Wang W, Strahl BD, Colaiácovo MP, Shi Y. A histone methylation network regulates transgenerational epigenetic memory in C. elegans. Cell Reports. 7: 113-26. PMID 24685137 DOI: 10.1016/j.celrep.2014.02.044  0.48
2014 Rothbart SB, Strahl BD. Interpreting the language of histone and DNA modifications. Biochimica Et Biophysica Acta. 1839: 627-43. PMID 24631868 DOI: 10.1016/j.bbagrm.2014.03.001  0.8
2014 Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, et al. Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function. Cell Reports. 6: 892-905. PMID 24565511 DOI: 10.1016/j.celrep.2014.01.029  0.48
2014 Klein BJ, Piao L, Xi Y, Rincon-Arano H, Rothbart SB, Peng D, Wen H, Larson C, Zhang X, Zheng X, Cortazar MA, Peña PV, Mangan A, Bentley DL, Strahl BD, et al. The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers. Cell Reports. 6: 325-35. PMID 24412361 DOI: 10.1016/j.celrep.2013.12.021  0.48
2013 Kinkelin K, Wozniak GG, Rothbart SB, Lidschreiber M, Strahl BD, Cramer P. Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proceedings of the National Academy of Sciences of the United States of America. 110: 15277-82. PMID 24003114 DOI: 10.1073/pnas.1311010110  0.8
2013 Gatchalian J, Fütterer A, Rothbart SB, Tong Q, Rincon-Arano H, Sánchez de Diego A, Groudine M, Strahl BD, Martínez-A C, van Wely KH, Kutateladze TG. Dido3 PHD modulates cell differentiation and division. Cell Reports. 4: 148-58. PMID 23831028 DOI: 10.1016/j.celrep.2013.06.014  0.48
2013 Ali M, Rincón-Arano H, Zhao W, Rothbart SB, Tong Q, Parkhurst SM, Strahl BD, Deng LW, Groudine M, Kutateladze TG. Molecular basis for chromatin binding and regulation of MLL5. Proceedings of the National Academy of Sciences of the United States of America. 110: 11296-301. PMID 23798402 DOI: 10.1073/pnas.1310156110  0.8
2013 Rothbart SB, Dickson BM, Ong MS, Krajewski K, Houliston S, Kireev DB, Arrowsmith CH, Strahl BD. Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation. Genes & Development. 27: 1288-98. PMID 23752590 DOI: 10.1101/gad.220467.113  0.48
2013 Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG. An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Molecular Cell. 49: 571-82. PMID 23273982 DOI: 10.1016/j.molcel.2012.11.026  0.48
2012 Ali M, Yan K, Lalonde ME, Degerny C, Rothbart SB, Strahl BD, Côté J, Yang XJ, Kutateladze TG. Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin. Journal of Molecular Biology. 424: 328-38. PMID 23063713 DOI: 10.1016/j.jmb.2012.10.004  0.48
2012 Rothbart SB, Krajewski K, Nady N, Tempel W, Xue S, Badeaux AI, Barsyte-Lovejoy D, Martinez JY, Bedford MT, Fuchs SM, Arrowsmith CH, Strahl BD. Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. Nature Structural & Molecular Biology. 19: 1155-60. PMID 23022729 DOI: 10.1038/nsmb.2391  0.48
2012 Rothbart SB, Krajewski K, Strahl BD, Fuchs SM. Peptide microarrays to interrogate the "histone code". Methods in Enzymology. 512: 107-35. PMID 22910205 DOI: 10.1016/B978-0-12-391940-3.00006-8  0.48
2012 Rothbart SB, Lin S, Britton LM, Krajewski K, Keogh MC, Garcia BA, Strahl BD. Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies. Scientific Reports. 2: 489. PMID 22761995 DOI: 10.1038/srep00489  0.48
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