| Year |
Citation |
Score |
| 2021 |
Ronayne CT, Jonnalagadda SK, Jonnalagadda S, Nelson GL, Solano LN, Palle H, Mani C, Rumbley J, Holy J, Mereddy VR. Synthesis and biological evaluation of a novel anticancer agent CBISC that induces DNA damage response and diminishes levels of mutant-p53. Biochemical and Biophysical Research Communications. 562: 127-132. PMID 34051576 DOI: 10.1016/j.bbrc.2021.05.062 |
0.327 |
|
| 2019 |
Nelson GL, Ronayne CT, Solano LN, Jonnalagadda SK, Jonnalagadda S, Rumbley J, Holy J, Rose-Hellekant T, Drewes LR, Mereddy VR. Development of Novel Silyl Cyanocinnamic Acid Derivatives as Metabolic Plasticity Inhibitors for Cancer Treatment. Scientific Reports. 9: 18266. PMID 31797891 DOI: 10.1038/S41598-019-54709-7 |
0.388 |
|
| 2019 |
Jonnalagadda S, Jonnalagadda SK, Ronayne CT, Nelson GL, Solano LN, Rumbley J, Holy J, Mereddy VR, Drewes LR. Novel N,N-dialkyl cyanocinnamic acids as monocarboxylate transporter 1 and 4 inhibitors. Oncotarget. 10: 2355-2368. PMID 31040927 DOI: 10.18632/Oncotarget.26760 |
0.441 |
|
| 2019 |
Magalhães-Novais S, Bermejo-Millo JC, Loureiro R, Mesquita KA, Domingues MR, Maciel E, Melo T, Baldeiras I, Erickson JR, Holy J, Potes Y, Coto-Montes A, Oliveira PJ, Vega-Naredo I. Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells. Autophagy. PMID 30990357 DOI: 10.1080/15548627.2019.1607694 |
0.321 |
|
| 2018 |
Carvalho FS, Morais CM, Holy J, Krasutsky D, Yemets SV, Krasutsky PA, Moreno AJ, Jurado AS, Oliveira PJ, Serafim TL. Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains. Chemico-Biological Interactions. PMID 30292691 DOI: 10.1016/J.Cbi.2018.10.002 |
0.419 |
|
| 2017 |
Zhou K, Diebel KW, Holy J, Skildum A, Odean E, Hicks DA, Schotl B, Abrahante JE, Spillman MA, Bemis LT. A tRNA fragment, tRF5-Glu, regulates BCAR3 expression and proliferation in ovarian cancer cells. Oncotarget. 8: 95377-95391. PMID 29221134 DOI: 10.18632/Oncotarget.20709 |
0.413 |
|
| 2017 |
Ronayne CT, Solano LN, Nelson GL, Lueth EA, Hubbard SL, Schumacher TJ, Gardner ZS, Jonnalagadda SK, Gurrapu S, Holy J, Mereddy VR. Synthesis and biological evaluation of 2-alkoxycarbonylallyl esters as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters. PMID 28129978 DOI: 10.1016/J.Bmcl.2017.01.037 |
0.31 |
|
| 2015 |
Berens EB, Holy JM, Riegel AT, Wellstein A. A Cancer Cell Spheroid Assay to Assess Invasion in a 3D Setting. Journal of Visualized Experiments : Jove. PMID 26649463 DOI: 10.3791/53409 |
0.319 |
|
| 2014 |
Serafim TL, Carvalho FS, Bernardo TC, Pereira GC, Perkins E, Holy J, Krasutsky DA, Kolomitsyna ON, Krasutsky PA, Oliveira PJ. New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death. Bioorganic & Medicinal Chemistry. 22: 6270-87. PMID 25245673 DOI: 10.1016/J.Bmc.2014.08.013 |
0.513 |
|
| 2014 |
Vega-Naredo I, Loureiro R, Mesquita KA, Barbosa IA, Tavares LC, Branco AF, Erickson JR, Holy J, Perkins EL, Carvalho RA, Oliveira PJ. Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells. Cell Death and Differentiation. 21: 1560-74. PMID 24832466 DOI: 10.1038/Cdd.2014.66 |
0.413 |
|
| 2014 |
Oliveira PJ, Perkins EL, Holy J. Vital imaging of multicellular spheroids. Methods in Molecular Biology (Clifton, N.J.). 1075: 227-41. PMID 24052355 DOI: 10.1007/978-1-60761-847-8_11 |
0.373 |
|
| 2013 |
Bernardo TC, Cunha-Oliveira T, Serafim TL, Holy J, Krasutsky D, Kolomitsyna O, Krasutsky P, Moreno AM, Oliveira PJ. Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition. Bioorganic & Medicinal Chemistry. 21: 7239-49. PMID 24156937 DOI: 10.1016/J.Bmc.2013.09.066 |
0.407 |
|
| 2013 |
Zhdankin O, Bomier M, Parke D, Holy J, Rose-Hellekant T. Abstract A03: Tumorigenesis involving expansion of CD24 high CD61 cells is abrogated by tamoxifen in mouse models of luminal breast cancer Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-A03 |
0.411 |
|
| 2013 |
Zhdankin O, Bomier M, Parke D, Holy J, Rose-Hellekant T. Abstract B004: Expansion of lineage negative, CD24high, CD61+ mammary cells is an early step in mammary tumorigenesis in NRL-TGFalpha and MMTV-c-neu but not MMTV-c-myc models of luminal breast cancer Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-B004 |
0.399 |
|
| 2012 |
Branco AF, Sampaio SF, Moreira AC, Holy J, Wallace KB, Baldeiras I, Oliveira PJ, Sardão VA. Differentiation-dependent doxorubicin toxicity on H9c2 cardiomyoblasts. Cardiovascular Toxicology. 12: 326-40. PMID 22744233 DOI: 10.1007/S12012-012-9177-8 |
0.433 |
|
| 2012 |
Vega-Naredo I, Loureiro R, Tavares LC, Branco AF, Burgeiro A, Erickson JR, Holy J, Perkins EL, Carvalho RA, Oliveira PJ. Mitochondrial behavior on cancer stem cells and differentiated cancer cells: A key element for metabolic remodeling and regulation of chemoresistance Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1817: S123-S124. DOI: 10.1016/J.Bbabio.2012.06.332 |
0.441 |
|
| 2011 |
Serafim TL, Carvalho FS, Marques MP, Calheiros R, Silva T, Garrido J, Milhazes N, Borges F, Roleira F, Silva ET, Holy J, Oliveira PJ. Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells. Chemical Research in Toxicology. 24: 763-74. PMID 21504213 DOI: 10.1021/Tx200126R |
0.495 |
|
| 2011 |
Holy J, Perkins E, Yu X. Adhesion, proliferation and differentiation of pluripotent stem cells on multi-walled carbon nanotubes Iet Nanobiotechnology. 5: 41-46. PMID 21495779 DOI: 10.1049/Iet-Nbt.2010.0014 |
0.339 |
|
| 2011 |
Branco AF, Pereira SL, Moreira AC, Holy J, Sardão VA, Oliveira PJ. Isoproterenol cytotoxicity is dependent on the differentiation state of the cardiomyoblast H9c2 cell line. Cardiovascular Toxicology. 11: 191-203. PMID 21455642 DOI: 10.1007/S12012-011-9111-5 |
0.453 |
|
| 2011 |
Fiuza SM, Holy J, Batista de Carvalho LA, Marques MP. Biologic activity of a dinuclear Pd(II)-spermine complex toward human breast cancer. Chemical Biology & Drug Design. 77: 477-88. PMID 21371266 DOI: 10.1111/J.1747-0285.2011.01081.X |
0.314 |
|
| 2010 |
Holy J, Kolomitsyna O, Krasutsky D, Oliveira PJ, Perkins E, Krasutsky PA. Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function. Bioorganic & Medicinal Chemistry. 18: 6080-8. PMID 20673631 DOI: 10.1016/j.bmc.2010.06.075 |
0.352 |
|
| 2010 |
Greene A, Parke D, Gingery A, Zhdankin O, Skildum A, Holy J, Perkins E, Rose‐Hellekant TA. Abstract B88: Local delivery of breast cancer chemopreventives using mesenchymal stem cells Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-B88 |
0.405 |
|
| 2009 |
Sardão VA, Oliveira PJ, Holy J, Oliveira CR, Wallace KB. Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts. Cancer Chemotherapy and Pharmacology. 64: 811-27. PMID 19184017 DOI: 10.1007/S00280-009-0932-X |
0.348 |
|
| 2009 |
Sardão VA, Oliveira PJ, Holy J, Oliveira CR, Wallace KB. Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets. Cell Biology and Toxicology. 25: 227-43. PMID 18386138 DOI: 10.1007/S10565-008-9070-1 |
0.457 |
|
| 2009 |
Greene A, Parke D, Zhdankin O, Gingery A, Skildum A, Holy J, Perkins E, Rose‐Hellekant T. Abstract A197: Development of an immunocompetent, triple negative, breast cancer model for stem cell based delivery of therapeutics Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A197 |
0.408 |
|
| 2008 |
Serafim TL, Matos JA, Sardão VA, Pereira GC, Branco AF, Pereira SL, Parke D, Perkins EL, Moreno AJ, Holy J, Oliveira PJ. Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells--nuclear vs. mitochondrial effects. Biochemical Pharmacology. 76: 1459-75. PMID 18692024 DOI: 10.1016/j.bcp.2008.07.013 |
0.387 |
|
| 2008 |
Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J. Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line. Cancer Chemotherapy and Pharmacology. 61: 1007-18. PMID 17661039 DOI: 10.1007/s00280-007-0558-9 |
0.342 |
|
| 2007 |
Pereira GC, Branco AF, Matos JA, Pereira SL, Parke D, Perkins EL, Serafim TL, Sardão VA, Santos MS, Moreno AJ, Holy J, Oliveira PJ. Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions. The Journal of Pharmacology and Experimental Therapeutics. 323: 636-49. PMID 17704354 DOI: 10.1124/jpet.107.128017 |
0.33 |
|
| 2007 |
Sardão VA, Oliveira PJ, Holy J, Oliveira CR, Wallace KB. Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death. Bmc Cell Biology. 8: 11. PMID 17362523 DOI: 10.1186/1471-2121-8-11 |
0.404 |
|
| 2004 |
Holy J. Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells. Cell Motility and the Cytoskeleton. 58: 253-68. PMID 15236356 DOI: 10.1002/Cm.20012 |
0.442 |
|
| 2004 |
Rolo AP, Palmeira CM, Holy JM, Wallace KB. Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 196-204. PMID 14976352 DOI: 10.1093/Toxsci/Kfh078 |
0.341 |
|
| 2002 |
Holy JM. Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells. Mutation Research. 518: 71-84. PMID 12063069 |
0.376 |
|
| 1999 |
Pierce T, Worman HJ, Holy J. Neuronal differentiation of NT2/D1 teratocarcinoma cells is accompanied by a loss of lamin A/C expression and an increase in lamin B1 expression Experimental Neurology. 157: 241-250. PMID 10364436 DOI: 10.1006/Exnr.1999.7060 |
0.364 |
|
| 1998 |
Holy J. Chlorpropham [isopropyl N-(3-chlorophenyl) carbamate] disrupts microtubule organization, cell division, and early development of sea urchin embryos Journal of Toxicology and Environmental Health. 54: 319-333. PMID 9638902 DOI: 10.1080/009841098158872 |
0.306 |
|
| 1990 |
Sobkowicz HM, Holy J, Scott GL. Ultrastructure of the intercalated body, a novel organelle associated with fluid forming cells in the organ of Corti. Journal of Electron Microscopy Technique. 15: 301-15. PMID 2374037 DOI: 10.1002/Jemt.1060150309 |
0.388 |
|
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