Yang Yu, M.D., Ph.D. - Publications

Affiliations: 
Internal Medicine University of Iowa, Iowa City, IA 

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yu Y, Xue B, Irfan NM, Beltz T, Weiss RM, Johnson AK, Felder RB, Wei SG. Reducing brain TACE activity improves neuroinflammation and cardiac function in heart failure rats. Frontiers in Physiology. 13: 1052304. PMID 36439267 DOI: 10.3389/fphys.2022.1052304  0.771
2022 Yu Y, Weiss RM, Wei SG. Brain Interleukin-17A contributes to neuroinflammation and cardiac dysfunction in rats with myocardial infarction. Frontiers in Neuroscience. 16: 1032434. PMID 36312009 DOI: 10.3389/fnins.2022.1032434  0.516
2022 Xue B, Yu Y, Beltz TG, Guo F, Wei SG, Kim Johnson A. Voluntary Exercise Eliminates Maternal Gestational Hypertension-Induced Hypertensive Response Sensitization to Postweaning High-Fat Diet in Male Adult Offspring. Hypertension (Dallas, Tex. : 1979). 101161HYPERTENSIONAH. PMID 35730432 DOI: 10.1161/HYPERTENSIONAHA.122.19608  0.404
2022 Xue B, Yu Y, Beltz TG, Guo F, Wei SG, Johnson AK. Loss of the Protective Effect of Estrogen Contributes to Maternal Gestational Hypertension-Induced Hypertensive Response Sensitization Elicited by Postweaning High-Fat Diet in Female Offspring. Journal of the American Heart Association. e023685. PMID 35014859 DOI: 10.1161/JAHA.121.023685  0.521
2021 Yu Y, Chen E, Weiss RM, Felder RB, Wei SG. Transforming Growth Factor-α Acts in Hypothalamic Paraventricular Nucleus to Upregulate ERK1/2 Signaling and Expression of Sympathoexcitatory Mediators in Heart Failure Rats. Neuroscience. PMID 34968668 DOI: 10.1016/j.neuroscience.2021.12.030  0.741
2021 Cao Y, Yu Y, Xue B, Wang Y, Chen X, Beltz TG, Johnson AK, Wei SG. IL (Interleukin)-17A Acts in the Brain to Drive Neuroinflammation, Sympathetic Activation, and Hypertension. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12118. PMID 34628936 DOI: 10.1161/HYPERTENSIONAHA.121.18219  0.494
2021 Xue B, Yu Y, Beltz TG, Guo F, Felder RB, Wei SG, Kim Johnson A. Maternal Angiotensin II-Induced Hypertension Sensitizes Postweaning High-Fat Diet-Elicited Hypertensive Response Through Increased Brain Reactivity in Rat Offspring. Journal of the American Heart Association. e022170. PMID 34482712 DOI: 10.1161/JAHA.121.022170  0.706
2021 Yu Y, Wei SG, Weiss RM, Felder RB. Silencing Epidermal Growth Factor Receptor in Hypothalamic Paraventricular Nucleus Reduces ERK1/2 Signaling and Sympathetic Excitation in Heart Failure Rats. Neuroscience. PMID 33540053 DOI: 10.1016/j.neuroscience.2021.01.025  0.77
2020 Wei SG, Yu Y, Felder RB. TNF-α-induced Sympathetic Excitation Requires EGFR and ERK1/2 Signaling in Cardiovascular Regulatory Regions of the Forebrain. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33337962 DOI: 10.1152/ajpheart.00606.2020  0.726
2020 Xue B, Xue J, Yu Y, Wei SG, Beltz TG, Felder RB, Johnson AK. Predator Scent-Induced Sensitization of Hypertension and Anxiety-like Behaviors. Cellular and Molecular Neurobiology. PMID 33201417 DOI: 10.1007/s10571-020-01005-y  0.697
2020 Naguib YW, Yu Y, Wei SG, Morris A, Givens BE, Mekkawy AI, Weiss RM, Felder RB, Salem AK. An Injectable Microparticle Formulation Provides Long-Term Inhibition of Hypothalamic ERK1/2 Activity and Sympathetic Excitation in Rats with Heart Failure. Molecular Pharmaceutics. PMID 32786958 DOI: 10.1021/Acs.Molpharmaceut.0C00501  0.747
2020 Naguib YW, Givens BE, Ho G, Yu Y, Wei SG, Weiss RM, Felder RB, Salem AK. An injectable microparticle formulation for the sustained release of the specific MEK inhibitor PD98059: in vitro evaluation and pharmacokinetics. Drug Delivery and Translational Research. PMID 32378175 DOI: 10.1007/S13346-020-00758-9  0.705
2020 Cao Y, Xue B, Yu Y, Johnson AK, Wei S. Abstract P136: Effects Of Sex Hormones On The Hemodynamic And Sympathetic Responses To Centrally Administered Tumor Necrosis Factor-α In Rats Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P136  0.624
2020 Bell B, Yu Y, Felder R, Wei S. Effects of Central Intervention of Tumor Necrosis Factor‐α Converting Enzyme (TACE) on Neuroinflammation and Cardiac Function in Heart Failure The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09213  0.689
2020 Yu Y, Cao Y, Felder RB, Wei S. Knockdown of Interleukin 17 Receptor A (IL‐17RA) in Paraventricular Nucleus of Hypothalamus Attenuates IL‐17‐induced Pressor Responses and Sympathetic Excitation The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04549  0.694
2020 Yu Y, Wei S, Weiss RM, Felder RB. Transforming Growth Factor‐α Acts via Epidermal Growth Factor Receptor to Increase p44/42 Mitogen‐Activated Protein Kinase Signaling and Expression of Excitatory Mediators in the Hypothalamic Paraventricular Nucleus in Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03644  0.704
2019 Yu Y, Cao Y, Bell B, Chen X, Weiss RM, Felder RB, Wei SG. Brain TACE (Tumor Necrosis Factor-α-Converting Enzyme) Contributes to Sympathetic Excitation in Heart Failure Rats. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11912. PMID 31154904 DOI: 10.1161/Hypertensionaha.119.12651  0.781
2019 Xue B, Yu Y, Wei SG, Beltz TG, Guo F, Felder RB, Johnson AK. Stress-induced sensitization of angiotensin II hypertension is reversed by blockade of angiotensin-converting enzyme or tumor necrosis factor-α. American Journal of Hypertension. PMID 31063551 DOI: 10.1093/Ajh/Hpz075  0.69
2019 Chen X, Yu Y, Bell B, Cao Y, Wang Y, Felder RB, Wei S. Abstract P2011: Chronic Systemic Administration of Pro-Inflammatory Cytokines Causes Cardiovascular Dysfunction and Downregulates Brain Expression of Regulator of G-Protein Signaling-10 in Rats Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P2011  0.732
2019 Yu Y, Wei S, Weiss RM, Felder RB. Abstract P2010: Silencing Epidermal Growth Factor Receptor Reduces P44/42 Mitogen-Activated Protein Kinase Signaling in the Hypothalamic Paraventricular Nucleus and Ameliorates Sympathetic Excitation in Rats With Heart Failure After Myocardial Infarction Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P2010  0.74
2019 Cao Y, Yu Y, Wang Y, Felder RB, Wei S. Abstract 022: Role of Interleukin-17 in the Regulation of Hemodynamics and Renal Sympathetic Nerve Activity in Rats Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.022  0.703
2018 Yu Y, Wei SG, Weiss RM, Felder RB. Sex Differences in the Central and Peripheral Manifestations of Ischemia-induced Heart Failure in Rats. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30289294 DOI: 10.1152/Ajpheart.00499.2018  0.757
2018 Yu Y, Wei SG, Weiss RM, Felder RB. Angiotensin II type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats. Neuroscience. PMID 29684507 DOI: 10.1016/J.Neuroscience.2018.04.012  0.787
2018 Li HT, Liu HH, Yang YX, Wang T, Zhou XL, Yu Y, Li SN, Zheng Y, Zhang P, Wang RL, Li JY, Wei SZ, Li K, Li PY, Qian LQ. Therapeutic Effects of a Traditional Chinese Medicine Formula Plus Tamoxifen vs. Tamoxifen for the Treatment of Mammary Gland Hyperplasia: A Meta-Analysis of Randomized Trials. Frontiers in Pharmacology. 9: 45. PMID 29456506 DOI: 10.3389/fphar.2018.00045  0.344
2018 Cao Y, Yu Y, Bell BB, Felder RB, Wei S. Abstract P290: Central Angiotensin II and Interleukin-1©¬ Upregulate Brain Tumor Necrosis Factor-¥å Converting Enzyme in the Rat Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P290  0.724
2017 Wei SG, Yu Y, Felder RB. Blood-borne Interleukin-1β Acts upon the Subfornical Organ to Upregulate the Sympathoexcitatory Milieu of the Hypothalamic Paraventricular Nucleus. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00211.2017. PMID 29167166 DOI: 10.1152/Ajpregu.00211.2017  0.722
2017 Xu C, Zhang Y, Yu Y, Li Y, Wei S. Suppression of Arabidopsis flowering by near-null magnetic field is mediated by auxin. Bioelectromagnetics. PMID 28940601 DOI: 10.1002/bem.22086  0.34
2017 Yu Y, Wei SG, Weiss RM, Felder RB. TNF-α receptor 1 knockdown in subfornical organ ameliorates sympathetic excitation and cardiac hemodynamics in heart failure rats. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00280.2017. PMID 28710070 DOI: 10.1152/Ajpheart.00280.2017  0.784
2017 Huang C, Zhu H, Yu Y, Ding Q, Jia F, Zhao B, Wei S, Gong D, Xu W, Ji M. Simultaneous determination of pyrametostrobin and its two metabolites in cucumber and soil using a quick, easy, cheap, effective, rugged, and safe method with HPLC-MS/MS. Journal of Separation Science. PMID 28387044 DOI: 10.1002/jssc.201700109  0.322
2016 Xu C, Yu Y, Zhang Y, Li Y, Wei S. Gibberellins are involved in effect of near-null magnetic field on Arabidopsis flowering. Bioelectromagnetics. PMID 27598690 DOI: 10.1002/bem.22004  0.33
2016 Wei S, Zhang M, Yu Y, Xue H, Lan X, Liu S, Hatch G, Chen L. HNF-4α regulated miR-122 contributes to development of gluconeogenesis and lipid metabolism disorders in Type 2 diabetic mice and in palmitate-treated HepG2 cells. European Journal of Pharmacology. PMID 27592052 DOI: 10.1016/J.Ejphar.2016.08.038  0.386
2016 Wei SG, Yu Y, Weiss RM, Felder RB. Endoplasmic reticulum stress increases brain MAPK signaling, inflammation and renin-angiotensin system activity and sympathetic nerve activity in heart failure. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00362.2016. PMID 27496879 DOI: 10.1152/Ajpheart.00362.2016  0.784
2016 Xue B, Yu Y, Zhang Z, Guo F, Beltz TG, Thunhorst RL, Felder RB, Johnson AK. Leptin Mediates High-Fat Diet Sensitization of Angiotensin II-Elicited Hypertension by Upregulating the Brain Renin-Angiotensin System and Inflammation. Hypertension. PMID 27021010 DOI: 10.1161/Hypertensionaha.115.06736  0.712
2016 Yu Y, Wei SG, Zhang ZH, Weiss RM, Felder RB. ERK1/2 MAPK Signaling in Hypothalamic Paraventricular Nucleus Contributes to Sympathetic Excitation in Rats with Heart Failure after Myocardial Infarction. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00703.2015. PMID 26801309 DOI: 10.1152/Ajpheart.00703.2015  0.771
2016 Yu Y, Wei S, Weiss RM, Felder RB. Tumor Necrosis Factor-α Receptor 1 (TNFR1) Knockdown in Subfornical Organ (SFO) Attenuates Central Expression of Excitatory Mediators and Ameliorates Peripheral Manifestations of Heart Failure in Rats after Myocardial Infarction The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.Lb719  0.738
2015 Xue B, Thunhorst RL, Yu Y, Guo F, Beltz TG, Felder RB, Johnson AK. Central Renin-Angiotensin System Activation and Inflammation Induced by High-Fat Diet Sensitize Angiotensin II-Elicited Hypertension. Hypertension. PMID 26573717 DOI: 10.1161/Hypertensionaha.115.06263  0.677
2015 Wei SG, Yu Y, Weiss RM, Felder RB. Inhibition of Brain Mitogen-Activated Protein Kinase Signaling Reduces Central Endoplasmic Reticulum Stress and Inflammation and Sympathetic Nerve Activity in Heart Failure Rats. Hypertension. PMID 26573710 DOI: 10.1161/Hypertensionaha.115.06329  0.772
2015 Yu Y, Xue BJ, Wei SG, Zhang ZH, Beltz TG, Guo F, Johnson AK, Felder RB. Activation of Central PPAR-γ Attenuates Angiotensin II-Induced Hypertension. Hypertension. 66: 403-11. PMID 26101342 DOI: 10.1161/Hypertensionaha.115.05726  0.778
2015 Wei SG, Yu Y, Zhang ZH, Felder RB. Proinflammatory cytokines upregulate sympathoexcitatory mechanisms in the subfornical organ of the rat. Hypertension. 65: 1126-33. PMID 25776070 DOI: 10.1161/Hypertensionaha.114.05112  0.743
2014 Wei SG, Zhang ZH, Yu Y, Felder RB. Central SDF-1/CXCL12 expression and its cardiovascular and sympathetic effects: the role of angiotensin II, TNF-α, and MAP kinase signaling. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1643-54. PMID 25260613 DOI: 10.1152/Ajpheart.00432.2014  0.77
2013 Wei SG, Zhang ZH, Beltz TG, Yu Y, Johnson AK, Felder RB. Subfornical organ mediates sympathetic and hemodynamic responses to blood-borne proinflammatory cytokines. Hypertension. 62: 118-25. PMID 23670302 DOI: 10.1161/Hypertensionaha.113.01404  0.752
2013 Yu Y, Xue BJ, Zhang ZH, Wei SG, Beltz TG, Guo F, Johnson AK, Felder RB. Early interference with p44/42 mitogen-activated protein kinase signaling in hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension. Hypertension. 61: 842-9. PMID 23438934 DOI: 10.1161/Hypertensionaha.111.00080  0.717
2013 Wei N, Yu Y, Schmidt T, Stanford C, Hong L. Effects of glucocorticoid receptor antagonist, RU486, on the proliferative and differentiation capabilities of bone marrow mesenchymal stromal cells in ovariectomized rats. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 760-7. PMID 23280517 DOI: 10.1002/Jor.22298  0.37
2012 Wei SG, Zhang ZH, Yu Y, Weiss RM, Felder RB. Central actions of the chemokine stromal cell-derived factor 1 contribute to neurohumoral excitation in heart failure rats. Hypertension. 59: 991-8. PMID 22493069 DOI: 10.1161/Hypertensionaha.111.188086  0.784
2012 Yu Y, Zhang ZH, Wei SG, Weiss RM, Felder RB. Peroxisome proliferator-activated receptor-γ regulates inflammation and renin-angiotensin system activity in the hypothalamic paraventricular nucleus and ameliorates peripheral manifestations of heart failure. Hypertension. 59: 477-84. PMID 22083161 DOI: 10.1161/Hypertensionaha.111.182345  0.781
2012 Zhang ZH, Yu Y, Wei SG, Felder RB. Aldosterone-induced brain MAPK signaling and sympathetic excitation are angiotensin II type-1 receptor dependent. American Journal of Physiology. Heart and Circulatory Physiology. 302: H742-51. PMID 22081704 DOI: 10.1152/Ajpheart.00856.2011  0.753
2011 Zhang ZH, Yu Y, Wei SG, Nakamura Y, Nakamura K, Felder RB. EP₃ receptors mediate PGE₂-induced hypothalamic paraventricular nucleus excitation and sympathetic activation. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1559-69. PMID 21803943 DOI: 10.1152/Ajpheart.00262.2011  0.709
2011 Xue B, Beltz TG, Yu Y, Guo F, Gomez-Sanchez CE, Hay M, Johnson AK. Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 300: H555-64. PMID 21112947 DOI: 10.1152/Ajpheart.00847.2010  0.446
2010 Yu Y, Zhang ZH, Wei SG, Serrats J, Weiss RM, Felder RB. Brain perivascular macrophages and the sympathetic response to inflammation in rats after myocardial infarction. Hypertension. 55: 652-9. PMID 20142564 DOI: 10.1161/Hypertensionaha.109.142836  0.757
2010 Zhang ZH, Yu Y, Wei SG, Felder RB. Centrally administered lipopolysaccharide elicits sympathetic excitation via NAD(P)H oxidase-dependent mitogen-activated protein kinase signaling. Journal of Hypertension. 28: 806-16. PMID 20027123 DOI: 10.1097/Hjh.0B013E3283358B6E  0.739
2009 Felder RB, Yu Y, Zhang ZH, Wei SG. Pharmacological treatment for heart failure: a view from the brain. Clinical Pharmacology and Therapeutics. 86: 216-20. PMID 19553933 DOI: 10.1038/Clpt.2009.117  0.713
2009 Wei SG, Zhang ZH, Yu Y, Felder RB. Systemically administered tempol reduces neuronal activity in paraventricular nucleus of hypothalamus and rostral ventrolateral medulla in rats. Journal of Hypertension. 27: 543-50. PMID 19330914 DOI: 10.1097/Hjh.0B013E3283200442  0.74
2009 Wei SG, Yu Y, Zhang ZH, Felder RB. Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1425-33. PMID 19286949 DOI: 10.1152/Ajpheart.00942.2008  0.714
2008 Wei SG, Yu Y, Zhang ZH, Weiss RM, Felder RB. Mitogen-activated protein kinases mediate upregulation of hypothalamic angiotensin II type 1 receptors in heart failure rats. Hypertension. 52: 679-86. PMID 18768402 DOI: 10.1161/Hypertensionaha.108.113639  0.74
2008 Wei SG, Yu Y, Zhang ZH, Weiss RM, Felder RB. Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats. Hypertension. 52: 342-50. PMID 18574076 DOI: 10.1161/Hypertensionaha.108.110445  0.784
2008 Yu Y, Wei SG, Zhang ZH, Gomez-Sanchez E, Weiss RM, Felder RB. Does aldosterone upregulate the brain renin-angiotensin system in rats with heart failure? Hypertension. 51: 727-33. PMID 18227408 DOI: 10.1161/Hypertensionaha.107.099796  0.774
2008 Zhang ZH, Yu Y, Kang YM, Wei SG, Felder RB. Aldosterone acts centrally to increase brain renin-angiotensin system activity and oxidative stress in normal rats. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1067-74. PMID 18162560 DOI: 10.1152/Ajpheart.01131.2007  0.751
2007 Han Y, Shi Z, Zhang F, Yu Y, Zhong MK, Gao XY, Wang W, Zhu GQ. Reactive oxygen species in the paraventricular nucleus mediate the cardiac sympathetic afferent reflex in chronic heart failure rats. European Journal of Heart Failure. 9: 967-73. PMID 17719272 DOI: 10.1016/j.ejheart.2007.07.004  0.401
2007 Yu Y, Zhang ZH, Wei SG, Chu Y, Weiss RM, Heistad DD, Felder RB. Central gene transfer of interleukin-10 reduces hypothalamic inflammation and evidence of heart failure in rats after myocardial infarction. Circulation Research. 101: 304-12. PMID 17569888 DOI: 10.1161/Circresaha.107.148940  0.752
2007 Yu Y, Kang YM, Zhang ZH, Wei SG, Chu Y, Weiss RM, Felder RB. Increased cyclooxygenase-2 expression in hypothalamic paraventricular nucleus in rats with heart failure: role of nuclear factor kappaB. Hypertension. 49: 511-8. PMID 17242297 DOI: 10.1161/01.Hyp.0000257356.20527.C5  0.762
2006 Kang YM, Zhang ZH, Johnson RF, Yu Y, Beltz T, Johnson AK, Weiss RM, Felder RB. Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure. Circulation Research. 99: 758-66. PMID 16960100 DOI: 10.1161/01.Res.0000244092.95152.86  0.728
2006 Zhang ZH, Kang YM, Yu Y, Wei SG, Schmidt TJ, Johnson AK, Felder RB. 11beta-hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation. Hypertension. 48: 127-33. PMID 16717146 DOI: 10.1161/01.Hyp.0000224296.96235.Dd  0.704
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