| Year |
Citation |
Score |
| 2020 |
Crawford KHD, Eguia R, Dingens AS, Loes AN, Malone KD, Wolf CR, Chu HY, Tortorici MA, Veesler D, Murphy M, Pettie D, King NP, Balazs AB, Bloom JD. Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays. Viruses. 12. PMID 32384820 DOI: 10.3390/V12050513 |
0.555 |
|
| 2020 |
Sourisseau M, Lawrence DJP, Schwarz MC, Storrs CH, Veit EC, Bloom JD, Evans MJ. Deep Mutational Scanning to Map How Zika Envelope Protein Mutations Affect Viral Growth and Antibody Escape Proceedings. 50: 93. DOI: 10.3390/proceedings2020050093 |
0.379 |
|
| 2019 |
Huang Q, Chan KY, Tobey IG, Chan YA, Poterba T, Boutros CL, Balazs AB, Daneman R, Bloom JM, Seed C, Deverman BE. Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids. Plos One. 14: e0225206. PMID 31725765 DOI: 10.1371/Journal.Pone.0225206 |
0.548 |
|
| 2019 |
Sourisseau M, Lawrence DJP, Schwarz MC, Storrs CH, Veit EC, Bloom JD, Evans MJ. Deep mutational scanning comprehensively maps how Zika envelope protein mutations affect viral growth and antibody escape. Journal of Virology. PMID 31511387 DOI: 10.1128/JVI.01291-19 |
0.371 |
|
| 2019 |
Soh YS, Moncla LH, Eguia R, Bedford T, Bloom JD. Comprehensive mapping of adaptation of the avian influenza polymerase protein PB2 to humans. Elife. 8. PMID 31038123 DOI: 10.7554/Elife.45079 |
0.311 |
|
| 2019 |
Hom N, Gentles L, Bloom JD, Lee KK. Deep mutational scan of the highly conserved influenza A M1 matrix protein reveals substantial intrinsic mutational tolerance. Journal of Virology. PMID 31019050 DOI: 10.1128/Jvi.00161-19 |
0.346 |
|
| 2019 |
Drummond DA, Bloom JD. A Nobel Prize for evolution Evolution. 73: 630-631. DOI: 10.1111/Evo.13697 |
0.49 |
|
| 2018 |
Phillips AM, Ponomarenko AI, Chen K, Ashenberg O, Miao J, McHugh SM, Butty VL, Whittaker CA, Moore CL, Bloom JD, Lin YS, Shoulders MD. Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones. Plos Biology. 16: e3000008. PMID 30222731 DOI: 10.1371/Journal.Pbio.3000008 |
0.631 |
|
| 2018 |
Phillips AM, Doud MB, Gonzalez LO, Butty VL, Lin YS, Bloom JD, Shoulders MD. Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin. Elife. 7. PMID 30188321 DOI: 10.7554/Elife.38795 |
0.32 |
|
| 2017 |
Ashenberg O, Padmakumar J, Doud MB, Bloom JD. Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA. Plos Pathogens. 13: e1006288. PMID 28346537 DOI: 10.1371/Journal.Ppat.1006288 |
0.65 |
|
| 2016 |
Doud MB, Bloom JD. Accurate Measurement of the Effects of All Amino-Acid Mutations on Influenza Hemagglutinin. Viruses. 8. PMID 27271655 DOI: 10.3390/v8060155 |
0.32 |
|
| 2015 |
Doud MB, Ashenberg O, Bloom JD. Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs. Molecular Biology and Evolution. 32: 2944-60. PMID 26226986 DOI: 10.1093/Molbev/Msv167 |
0.662 |
|
| 2014 |
Thyagarajan B, Bloom JD. The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin. Elife. 3. PMID 25006036 DOI: 10.7554/eLife.03300 |
0.344 |
|
| 2013 |
Ashenberg O, Gong LI, Bloom JD. Mutational effects on stability are largely conserved during protein evolution. Proceedings of the National Academy of Sciences of the United States of America. 110: 21071-6. PMID 24324165 DOI: 10.1073/Pnas.1314781111 |
0.697 |
|
| 2013 |
Balazs AB, Bloom JD, Hong CM, Rao DS, Baltimore D. Broad protection against influenza infection by vectored immunoprophylaxis in mice. Nature Biotechnology. 31: 647-52. PMID 23728362 DOI: 10.1038/Nbt.2618 |
0.659 |
|
| 2013 |
Gong LI, Suchard MA, Bloom JD. Stability-mediated epistasis constrains the evolution of an influenza protein. Elife. 2: e00631. PMID 23682315 DOI: 10.7554/Elife.00631 |
0.323 |
|
| 2013 |
Ashenberg O, Gong LI, Bloom JD. Mutational effects on stability are largely conserved during protein evolution Proceedings of the National Academy of Sciences of the United States of America. 110: 21071-21076. DOI: 10.1073/pnas.1314781111 |
0.682 |
|
| 2012 |
Liberles DA, Teichmann SA, Bahar I, Bastolla U, Bloom J, Bornberg-Bauer E, Colwell LJ, de Koning AP, Dokholyan NV, Echave J, Elofsson A, Gerloff DL, Goldstein RA, Grahnen JA, Holder MT, et al. The interface of protein structure, protein biophysics, and molecular evolution. Protein Science : a Publication of the Protein Society. 21: 769-85. PMID 22528593 DOI: 10.1002/Pro.2071 |
0.355 |
|
| 2011 |
Bloom JD, Nayak JS, Baltimore D. A computational-experimental approach identifies mutations that enhance surface expression of an oseltamivir-resistant influenza neuraminidase. Plos One. 6: e22201. PMID 21799795 DOI: 10.1371/journal.pone.0022201 |
0.465 |
|
| 2010 |
Bloom JD, Gong LI, Baltimore D. Permissive secondary mutations enable the evolution of influenza oseltamivir resistance. Science (New York, N.Y.). 328: 1272-5. PMID 20522774 DOI: 10.1126/science.1187816 |
0.46 |
|
| 2010 |
Jäckel C, Bloom JD, Kast P, Arnold FH, Hilvert D. Consensus protein design without phylogenetic bias. Journal of Molecular Biology. 399: 541-6. PMID 20433850 DOI: 10.1016/J.Jmb.2010.04.039 |
0.556 |
|
| 2009 |
Bloom JD, Arnold FH. In the light of directed evolution: pathways of adaptive protein evolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 9995-10000. PMID 19528653 DOI: 10.1073/Pnas.0901522106 |
0.558 |
|
| 2007 |
Li Y, Drummond DA, Sawayama AM, Snow CD, Bloom JD, Arnold FH. A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments. Nature Biotechnology. 25: 1051-6. PMID 17721510 DOI: 10.1038/Nbt1333 |
0.64 |
|
| 2007 |
Bloom JD, Lu Z, Chen D, Raval A, Venturelli OS, Arnold FH. Evolution favors protein mutational robustness in sufficiently large populations. Bmc Biology. 5: 29. PMID 17640347 DOI: 10.1186/1741-7007-5-29 |
0.539 |
|
| 2007 |
Bloom JD, Romero PA, Lu Z, Arnold FH. Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution. Biology Direct. 2: 17. PMID 17598905 DOI: 10.1186/1745-6150-2-17 |
0.694 |
|
| 2007 |
Bloom JD, Arnold FH, Wilke CO. Breaking proteins with mutations: threads and thresholds in evolution. Molecular Systems Biology. 3: 76. PMID 17262035 DOI: 10.1038/Msb4100119 |
0.449 |
|
| 2007 |
Bloom JD, Raval A, Wilke CO. Thermodynamics of neutral protein evolution. Genetics. 175: 255-66. PMID 17110496 DOI: 10.1534/genetics.106.061754 |
0.377 |
|
| 2007 |
Li Y, Drummond DA, Sawayama AM, Snow CD, Bloom JD, Arnold FH. Erratum: Corrigendum: A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments Nature Biotechnology. 25: 1488-1488. DOI: 10.1038/Nbt1207-1488D |
0.586 |
|
| 2006 |
Bloom JD, Drummond DA, Arnold FH, Wilke CO. Structural determinants of the rate of protein evolution in yeast. Molecular Biology and Evolution. 23: 1751-61. PMID 16782762 DOI: 10.1093/Molbev/Msl040 |
0.642 |
|
| 2006 |
Otey CR, Landwehr M, Endelman JB, Hiraga K, Bloom JD, Arnold FH. Structure-guided recombination creates an artificial family of cytochromes P450. Plos Biology. 4: e112. PMID 16594730 DOI: 10.1371/Journal.Pbio.0040112 |
0.712 |
|
| 2006 |
Bloom JD, Labthavikul ST, Otey CR, Arnold FH. Protein stability promotes evolvability. Proceedings of the National Academy of Sciences of the United States of America. 103: 5869-74. PMID 16581913 DOI: 10.1073/Pnas.0510098103 |
0.565 |
|
| 2005 |
Drummond DA, Bloom JD, Adami C, Wilke CO, Arnold FH. Why highly expressed proteins evolve slowly. Proceedings of the National Academy of Sciences of the United States of America. 102: 14338-43. PMID 16176987 DOI: 10.1073/Pnas.0504070102 |
0.647 |
|
| 2005 |
Wilke CO, Bloom JD, Drummond DA, Raval A. Predicting the tolerance of proteins to random amino acid substitution. Biophysical Journal. 89: 3714-20. PMID 16150971 DOI: 10.1529/Biophysj.105.062125 |
0.541 |
|
| 2005 |
Bloom JD, Meyer MM, Meinhold P, Otey CR, MacMillan D, Arnold FH. Evolving strategies for enzyme engineering. Current Opinion in Structural Biology. 15: 447-52. PMID 16006119 DOI: 10.1016/J.Sbi.2005.06.004 |
0.731 |
|
| 2005 |
Bloom JD, Silberg JJ, Wilke CO, Drummond DA, Adami C, Arnold FH. Thermodynamic prediction of protein neutrality. Proceedings of the National Academy of Sciences of the United States of America. 102: 606-11. PMID 15644440 DOI: 10.1073/Pnas.0406744102 |
0.724 |
|
| 2004 |
Bloom JD, Wilke CO, Arnold FH, Adami C. Stability and the evolvability of function in a model protein. Biophysical Journal. 86: 2758-64. PMID 15111394 DOI: 10.1016/S0006-3495(04)74329-5 |
0.488 |
|
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