Paul Smith, Ph.D. - Publications

University of East Anglia University of East Anglia, Norwich, England, United Kingdom 

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Year Citation  Score
2019 Curry L, Almukhtar H, Alahmed J, Roberts R, Smith PA. Simvastatin inhibits L-type Ca2+-channel activity through impairment of mitochondrial function. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30859212 DOI: 10.1093/toxsci/kfz068  0.317
2009 Smith PA. N-type Ca2+-channels in murine pancreatic β-cells are inhibited by an exclusive coupling with somatostatin receptor subtype 1 Endocrinology. 150: 741-748. PMID 18845633 DOI: 10.1210/en.2008-0883  0.319
2006 Daunt M, Dale O, Smith PA. Somatostatin inhibits oxidative respiration in pancreatic β-cells Endocrinology. 147: 1527-1535. PMID 16357046 DOI: 10.1210/en.2005-0873  0.34
2001 Smith PA, Sellers LA, Humphrey PP. Somatostatin activates two types of inwardly rectifying K+ channels in MIN-6 cells. The Journal of Physiology. 532: 127-42. PMID 11283230  0.612
1999 Smith PA, Proks P, Ashcroft FM. Quantal analysis of 5-hydroxytryptamine release from mouse pancreatic beta-cells. The Journal of Physiology. 521: 651-64. PMID 10601496 DOI: 10.1111/J.1469-7793.1999.00651.X  0.533
1999 Dalle S, Smith P, Blache P, Le-Nguyen D, Le Brigand L, Bergeron F, Ashcroft FM, Bataille D. Miniglucagon (glucagon 19-29), a potent and efficient inhibitor of secretagogue-induced insulin release through a Ca2+ pathway. The Journal of Biological Chemistry. 274: 10869-76. PMID 10196164 DOI: 10.1074/Jbc.274.16.10869  0.563
1999 Smith PA, Proks P, Moorhouse A. Direct effects of tolbutamide on mitochondrial function, intracellular Ca2+ and exocytosis in pancreatic β-cells Pflugers Archiv European Journal of Physiology. 437: 577-588. PMID 10089571 DOI: 10.1007/s004240050820  0.315
1998 Smith PA, Proks P. Inhibition of the ATP-sensitive potassium channel from mouse pancreatic β-cells by surfactants British Journal of Pharmacology. 124: 529-539. PMID 9647478 DOI: 10.1038/sj.bjp.0701858  0.305
1998 Hughes SJ, Faehling M, Thorneley CW, Proks P, Ashcroft FM, Smith PA. Electrophysiological and metabolic characterization of single beta-cells and islets from diabetic GK rats. Diabetes. 47: 73-81. PMID 9421377 DOI: 10.2337/Diab.47.1.73  0.554
1997 Smith P, Millard PJ, Fewtrell CM, Ashcroft FM. Heterogeneity of beta-cell Ca2+ responses to glucose. Advances in Experimental Medicine and Biology. 426: 253-7. PMID 9544282 DOI: 10.1007/978-1-4899-1819-2_35  0.58
1997 Smith PA, Sakura H, Coles B, Gummerson N, Proks P, Ashcroft FM. Electrogenic arginine transport mediates stimulus-secretion coupling in mouse pancreatic beta-cells. The Journal of Physiology. 499: 625-35. PMID 9130159 DOI: 10.1113/Jphysiol.1997.Sp021955  0.495
1997 Smith P, Millard PJ, Fewtrell CMS, Ashcroft FM. Heterogeneity of β-cell Ca2+ responses to glucose Advances in Experimental Medicine and Biology. 426: 253-257.  0.493
1996 Eliasson L, Proks P, Ammälä C, Ashcroft FM, Bokvist K, Renström E, Rorsman P, Smith PA. Endocytosis of secretory granules in mouse pancreatic beta-cells evoked by transient elevation of cytosolic calcium. The Journal of Physiology. 493: 755-67. PMID 8799897 DOI: 10.1113/Jphysiol.1996.Sp021420  0.64
1996 Ammälä C, Moorhouse A, Gribble F, Ashfield R, Proks P, Smith PA, Sakura H, Coles B, Ashcroft SJ, Ashcroft FM. Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels. Nature. 379: 545-8. PMID 8596634 DOI: 10.1038/379545A0  0.551
1995 Sakura H, Ammälä C, Smith PA, Gribble FM, Ashcroft FM. Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle. Febs Letters. 377: 338-44. PMID 8549751 DOI: 10.1016/0014-5793(95)01369-5  0.534
1995 Smith PA, Duchen MR, Ashcroft FM. A fluorimetric and amperometric study of calcium and secretion in isolated mouse pancreatic beta-cells. Pflã¼Gers Archiv : European Journal of Physiology. 430: 808-18. PMID 7478937 DOI: 10.1007/Bf00386180  0.572
1994 Smith PA, Williams BA, Ashcroft FM. Block of ATP-sensitive K+ channels in isolated mouse pancreatic beta-cells by 2,3-butanedione monoxime. British Journal of Pharmacology. 112: 143-9. PMID 8032636 DOI: 10.1111/J.1476-5381.1994.Tb13044.X  0.559
1994 Ellory JC, Culliford SJ, Smith PA, Wolowyk MW, Knaus EE. Specific inhibition of Ca-activated K channels in red cells by selected dihydropyridine derivatives British Journal of Pharmacology. 111: 903-905. PMID 8019767 DOI: 10.1111/J.1476-5381.1994.Tb14823.X  0.311
1994 Ashcroft FM, Proks P, Smith PA, Ammälä C, Bokvist K, Rorsman P. Stimulus-secretion coupling in pancreatic beta cells. Journal of Cellular Biochemistry. 55: 54-65. PMID 7929618 DOI: 10.1002/Jcb.240550007  0.665
1994 Ashcroft FM, Coles B, Kenna S, Proks P, Röper J, Reid J, Smith PA, Takano M. The KATP and Kv channels are distinct entities: a reply to Edwards and Weston. Cardiovascular Research. 28: 738-40; discussion 7. PMID 7923273 DOI: 10.1093/Cvr/28.6.738  0.489
1993 Duchen MR, Smith PA, Ashcroft FM. Substrate-dependent changes in mitochondrial function, intracellular free calcium concentration and membrane channels in pancreatic beta-cells. The Biochemical Journal. 294: 35-42. PMID 8363584 DOI: 10.1042/Bj2940035  0.554
1993 Williams BA, Smith PA, Leow K, Shimizu S, Gray DW, Ashcroft FM. Two types of potassium channel regulated by ATP in pancreatic B cells isolated from a type-2 diabetic human. Pflã¼Gers Archiv : European Journal of Physiology. 423: 265-73. PMID 8321630 DOI: 10.1007/Bf00374405  0.575
1993 Smith PA, Ashcroft FM, Fewtrell CMS. Permeation and gating properties of the L-Type calcium channel in mouse pancreatic β cells Journal of General Physiology. 101: 767-797. PMID 7687645  0.319
1990 Smith PA, Ashcroft FM, Rorsman P. Simultaneous recordings of glucose dependent electrical activity and ATP-regulated K(+)-currents in isolated mouse pancreatic beta-cells. Febs Letters. 261: 187-90. PMID 2407553 DOI: 10.1016/0014-5793(90)80667-8  0.659
1990 Bokvist K, Rorsman P, Smith PA. Block of ATP-regulated and Ca2(+)-activated K+ channels in mouse pancreatic beta-cells by external tetraethylammonium and quinine. The Journal of Physiology. 423: 327-42. PMID 2201761 DOI: 10.1113/Jphysiol.1990.Sp018025  0.595
1990 Bokvist K, Rorsman P, Smith PA. Effects of external tetraethylammonium ions and quinine on delayed rectifying K+ channels in mouse pancreatic beta-cells. The Journal of Physiology. 423: 311-25. PMID 2201760 DOI: 10.1113/Jphysiol.1990.Sp018024  0.56
1990 Smith PA, Bokvist K, Arkhammar P, Berggren PO, Rorsman P. Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells. The Journal of General Physiology. 95: 1041-59. PMID 2197368 DOI: 10.1085/Jgp.95.6.1041  0.61
1990 Rorsman P, Berggren PO, Smith PA. Glucose in glucagon release. Nature. 344: 716. PMID 2184365 DOI: 10.1038/344716b0  0.454
1990 Ashcroft FM, Kelly RP, Smith PA. Two types of Ca channel in rat pancreatic beta-cells. Pflã¼Gers Archiv : European Journal of Physiology. 415: 504-6. PMID 1690385 DOI: 10.1007/Bf00373633  0.578
1989 Smith PA, Bokvist K, Rorsman P. Demonstration of A-currents in pancreatic islet cells. PflüGers Archiv : European Journal of Physiology. 413: 441-3. PMID 2648325 DOI: 10.1007/Bf00584497  0.469
1989 Rorsman P, Berggren PO, Bokvist K, Ericson H, Möhler H, Ostenson CG, Smith PA. Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels. Nature. 341: 233-6. PMID 2550826 DOI: 10.1038/341233A0  0.549
1989 Smith PA, Rorsman P, Ashcroft FM. Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic beta-cells. Nature. 342: 550-3. PMID 2479839 DOI: 10.1038/342550A0  0.688
Low-probability matches (unlikely to be authored by this person)
2019 Fedorenko OA, Pulbutr P, Banke E, Akaniro-Ejim NE, Bentley DC, Olofsson CS, Chan S, Smith PA. CaV1.2 and CaV1.3 voltage-gated L-type Ca2+ channels in rat white fat adipocytes. The Journal of Endocrinology. PMID 31770099 DOI: 10.1530/JOE-19-0493  0.295
2002 Virsolvy A, Smith P, Bertrand G, Gros L, Héron L, Salazar G, Puech R, Bataille D. Block of Ca 2+ -channels by alpha-endosulphine inhibits insulin release British Journal of Pharmacology. 135: 1810-1818. PMID 11934823 DOI: 10.1038/sj.bjp.0704635  0.292
2001 Thomas P, Smith PA. Tetrabutylammonium: A selective blocker of the somatostatin-activated hyperpolarizing current in mouse AtT-20 corticotrophs Pflugers Archiv European Journal of Physiology. 441: 816-823. PMID 11316266 DOI: 10.1007/s004240000488  0.288
2014 Bentley DC, Pulbutr P, Chan S, Smith PA. Etiology of the membrane potential of rat white fat adipocytes. American Journal of Physiology. Endocrinology and Metabolism. 307: E161-75. PMID 24865982 DOI: 10.1152/ajpendo.00446.2013  0.281
1990 Oosawa Y, Ashcroft SJH, Smith PA. Ca2+-activated K+ channels from an insulin-secreting β-cell line incorporated into planar lipid bilayers Journal of Physiology. 430: 123P.  0.269
1995 Willmotti NJ, Galionei A, Smith PA. A cADP-ribose antagonist does not inhibit secretagogue-, caffeine- and nitric oxide-induced Ca2+ responses in rat pancreatic β-cells Cell Calcium. 18: 411-419. PMID 8581969 DOI: 10.1016/0143-4160(95)90056-X  0.267
1990 Peers C, Smith PA, Nye PC. Ligustrazine selectively blocks ATP-sensitive K+ channels in mouse pancreatic beta cells. Febs Letters. 261: 5-7. PMID 2407556 DOI: 10.1016/0014-5793(90)80622-P  0.267
2007 Judge SI, Smith PJ, Stewart PE, Bever CT. Potassium channel blockers and openers as CNS neurologic therapeutic agents. Recent Patents On Cns Drug Discovery. 2: 200-28. PMID 18221232 DOI: 10.2174/157488907782411765  0.263
1991 Kiranadi B, Bangham JA, Smith PA. Inhibition of electrical activity in mouse pancreatic β-cells by the ATP/ADP translocase inhibitor, bongkrekic acid Febs Letters. 283: 93-96. PMID 2037079 DOI: 10.1016/0014-5793(91)80561-G  0.26
1991 Smith PA, Fewtrell C, Ashcroft F. Ba currents through L-type Ca channels in isolated mouse pancreatic β-cells Journal of Physiology. 434: 35P.  0.253
1995 Willmott NJ, Galione A, Smith PA. Nitric oxide induces intracellular Ca2+ mobilization and increases secretion of incorporated 5-hydroxytryptamine in rat pancreatic β-cells Febs Letters. 371: 99-104. PMID 7672132 DOI: 10.1016/0014-5793(95)00848-4  0.244
2009 Judge SI, Smith PJ. Patents related to therapeutic activation of K(ATP) and K(2P) potassium channels for neuroprotection: ischemic/hypoxic/anoxic injury and general anesthetics. Expert Opinion On Therapeutic Patents. 19: 433-60. PMID 19441925 DOI: 10.1517/13543770902765151  0.243
1991 Ashcroft FM, Smith PA, Fewtrell C. L-type Ca-channel activity recorded at a low divalent cation concentration Biomedical Research. 12: 61-63.  0.243
2019 de Koning L, Decaudin D, El Botty R, Nicolas A, Carita G, Schuller M, Ouine B, Cartier A, Naguez A, Fleury J, Cooke V, Wylie A, Smith P, Marangoni E, Gentien D, et al. PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma. Cancers. 11. PMID 31146482 DOI: 10.3390/Cancers11060751  0.236
1993 Smith PA, Williams BA, Ashcroft FM. Block of ATP-sensitive K+ channels in isolated mouse pancreatic β-cells by 2,3-butanedione monoxime Journal of Physiology. 467: 265P.  0.234
1992 Chen H, Smith PA. M-currents in frog sympathetic ganglion cells: manipulation of membrane phosphorylation. British Journal of Pharmacology. 105: 329-34. PMID 1373098 DOI: 10.1111/J.1476-5381.1992.Tb14254.X  0.233
1990 Ashcroft FM, Fewtrell C, Oosawa Y, Rorsman P, Smith PA. ATP-regulated K channels modulate electrical activity in mouse isolated pancreatic β-cells Journal of Physiology. 424: 27P.  0.23
2001 Chen H, Kurennyi DE, Smith PA. Modulation of M-channel conductance by adenosine 5' triphosphate in bullfrog sympathetic B-neurones. Journal of Autonomic Pharmacology. 21: 57-62. PMID 11422579 DOI: 10.1046/J.1365-2680.2001.00208.X  0.229
2016 Austin V, Savary J, Smith P. Burrowing Owls Athene cunicularia (Strigidae) respond with increased vigilance to calls of the Curl-crested Jay Cyanocorax cristatellus (Corvidae) in the Paraguayan Cerrado Revista Brasileira De Ornitologia - Brazilian Journal of Ornithology. 24: 1-8. DOI: 10.1007/Bf03544321  0.221
2018 Real J, Miranda C, Olofsson CS, Smith PA. Lipophilicity predicts the ability of nonsulphonylurea drugs to block pancreatic beta-cell K channels and stimulate insulin secretion; statins as a test case. Endocrinology, Diabetes & Metabolism. 1: e00017. PMID 30815553 DOI: 10.1002/edm2.17  0.22
2020 Meyer N, Bollache L, Dechaume-Moncharmont FX, Moreau J, Afonso E, Angerbjörn A, Bêty J, Ehrich D, Gilg V, Giroux MA, Hansen J, Lanctot RB, Lang J, Lecomte N, McKinnon L, ... ... Smith P, et al. Nest attentiveness drives nest predation in arctic sandpipers Oikos. DOI: 10.1111/Oik.07311  0.22
2017 Elmorsy E, Al-Ghafari A, Helaly ANM, Hisab AS, Oehrle B, Smith PA. Therapeutic concentrations of antidepressants inhibit pancreatic beta-cell function via mitochondrial complex inhibition. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28482088 DOI: 10.1093/toxsci/kfx090  0.218
2004 Horii A, Russell NA, Smith PF, Darlington CL, Bilkey DK. Vestibular influences on CA1 neurons in the rat hippocampus: an electrophysiological study in vivo. Experimental Brain Research. 155: 245-50. PMID 14666395 DOI: 10.1007/s00221-003-1725-9  0.213
2017 Smith P, Matthews A. Breeding observations on Buff-bellied Puffbird Notharchus swainsoni (Piciformes: Bucconidae) at Rancho Laguna Blanca, San Pedro department, Paraguay Revista Brasileira De Ornitologia - Brazilian Journal of Ornithology. 25: 20-23. DOI: 10.1007/Bf03544372  0.206
2018 Palmer PI, O'Doherty S, Allen G, Bower K, Bösch H, Chipperfield MP, Connors S, Dhomse S, Feng L, Finch DP, Gallagher MW, Gloor E, Gonzi S, Harris NRP, Helfter C, ... ... Smith P, et al. A measurement-based verification framework for UK greenhouse gas emissions: an overview of the Greenhouse gAs Uk and Global Emissions (GAUGE) project Atmospheric Chemistry and Physics. 18: 11753-11777. DOI: 10.5194/Acp-18-11753-2018  0.201
2016 Smith P, Garrett KL. The juvenile plumage of Quebracho Crested-Tinamou Eudromia formosa (Aves: Tinamidae) Revista Brasileira De Ornitologia - Brazilian Journal of Ornithology. 24: 335-337. DOI: 10.1007/Bf03544363  0.201
2019 Cabello-Olmo M, Araña M, Radichev I, Smith P, Huarte E, Barajas M. New Insights into Immunotherapy Strategies for Treating Autoimmune Diabetes. International Journal of Molecular Sciences. 20. PMID 31561568 DOI: 10.3390/ijms20194789  0.2
2018 Bianchi B, Smith PA, Abriel H. The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration. Molecular Brain. 11: 41. PMID 29996905 DOI: 10.1186/S13041-018-0385-4  0.2
2014 Smith P, Lesterhuis AJ, Clay RP. Status and distribution of the doraditos (tyrannidae: Pseudocolopteryx ) in Paraguay, including a new country record Revista Brasileira De Ornitologia - Brazilian Journal of Ornithology. 22: 9. DOI: 10.1007/Bf03544244  0.193
2017 Brown S, Gratto-Trevor C, Porter R, Weiser EL, Mizrahi D, Bentzen R, Boldenow M, Clay R, Freeman S, Giroux M, Kwon E, Lank DB, Lecomte N, Liebezeit J, Loverti V, ... ... Smith P, et al. Migratory connectivity of Semipalmated Sandpipers and implications for conservation The Condor. 119: 207-224. DOI: 10.1650/Condor-16-55.1  0.192
2006 Cook GA, Pajewski R, Aburi M, Smith PE, Prakash O, Tomich JM, Gokel GW. NMR structure and dynamic studies of an anion-binding, channel-forming heptapeptide. Journal of the American Chemical Society. 128: 1633-8. PMID 16448136 DOI: 10.1021/Ja055887J  0.19
2008 Goddard M, Zheng Y, Darlington CL, Smith PF. Synaptic protein expression in the medial temporal lobe and frontal cortex following chronic bilateral vestibular loss. Hippocampus. 18: 440-4. PMID 18306302 DOI: 10.1002/hipo.20416  0.188
2014 Hostettler H, Smith P. Long-trained Nightjar (Macropsalis forcipata) (Aves, Caprimulgidae): first Paraguayan record Revista Brasileira De Ornitologia - Brazilian Journal of Ornithology. 22: 413-415. DOI: 10.1007/Bf03544277  0.188
2004 Smith P, Drummond T, Cipolla R. Layered motion segmentation and depth ordering by tracking edges Ieee Transactions On Pattern Analysis and Machine Intelligence. 26: 479-494. PMID 15382652 DOI: 10.1109/Tpami.2004.1265863  0.182
2003 Zheng Y, Kerr DS, Darlington CL, Smith PF. Unilateral inner ear damage results in lasting changes in hippocampal CA1 field potentials in vitro Hippocampus. 13: 873-878. PMID 14750650 DOI: 10.1002/hipo.10174  0.176
2008 Goddard M, Zheng Y, Darlington CL, Smith PF. Monoamine transporter and enzyme expression in the medial temporal lobe and frontal cortex following chronic bilateral vestibular loss. Neuroscience Letters. 437: 107-10. PMID 18436376 DOI: 10.1016/j.neulet.2008.03.073  0.172
2008 Friday BB, Yu C, Dy GK, Smith PD, Wang L, Thibodeau SN, Adjei AA. BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins. Cancer Research. 68: 6145-53. PMID 18676837 DOI: 10.1158/0008-5472.CAN-08-1430  0.159
2010 Hannigan A, Smith P, Kalna G, Lo Nigro C, Orange C, O'Brien DI, Shah R, Syed N, Spender LC, Herrera B, Thurlow JK, Lattanzio L, Monteverde M, Maurer ME, Buffa FM, et al. Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter. The Journal of Clinical Investigation. 120: 2842-57. PMID 20592473 DOI: 10.1172/JCI36125  0.157
2018 Yapa AS, Wang H, Wendel SO, Shrestha TB, Kariyawasam NL, Kalubowilage M, Perera AS, Pyle M, Basel MT, Malalasekera AP, Manawadu H, Yu J, Toledo Y, Ortega R, Thapa PS, ... Smith PE, et al. Peptide nanosponges designed for rapid uptake by leukocytes and neural stem cells. Rsc Advances. 8: 16052-16060. PMID 35542227 DOI: 10.1039/c8ra00717a  0.155
2004 Lindsay L, Liu P, Gliddon C, Zheng Y, Smith PF, Darlington CL. Cytosolic glucocorticoid receptor expression in the rat vestibular nucleus and hippocampus following unilateral vestibular deafferentation. Experimental Brain Research. 162: 309-14. PMID 15580339 DOI: 10.1007/s00221-004-2168-7  0.154
1986 Bangham JA, Smith PA, Croghan PC. Modelling the beta-cell electrical activity Advances in Experimental Medicine and Biology. 211: 265-278. PMID 2440246  0.151
2020 Jiang J, Smith P, van Rossum MCW. Electro-physiology Models of Cells with Spherical Geometry with Non-conducting Center. Bulletin of Mathematical Biology. 82: 147. PMID 33211192 DOI: 10.1007/s11538-020-00828-6  0.151
2014 Tatarkiewicz K, Hargrove DM, Jodka CM, Gedulin BR, Smith PA, Hoyt JA, Lwin A, Collins L, Mamedova L, Levy OE, D'Souza L, Janssen S, Srivastava V, Ghosh SS, Parkes DG. A novel long-acting glucose-dependent insulinotropic peptide analogue: enhanced efficacy in normal and diabetic rodents. Diabetes, Obesity & Metabolism. 16: 75-85. PMID 23859463 DOI: 10.1111/dom.12181  0.148
1989 Zidichouski JA, Kehoe MP, Wong K, Smith PA. Elevation of intracellular cyclic AMP concentration fails to inhibit adrenaline-induced hyperpolarization in amphibian sympathetic neurons. British Journal of Pharmacology. 96: 779-84. PMID 2545297 DOI: 10.1111/J.1476-5381.1989.Tb11883.X  0.148
2007 Athanasiou A, Smith PA, Vakilpour S, Kumaran NM, Turner AE, Bagiokou D, Layfield R, Ray DE, Westwell AD, Alexander SP, Kendall DA, Lobo DN, Watson SA, Lophatanon A, Muir KA, et al. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications. 354: 50-5. PMID 17214968 DOI: 10.1016/J.Bbrc.2006.12.179  0.147
2010 Gopal YN, Deng W, Woodman SE, Komurov K, Ram P, Smith PD, Davies MA. Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells. Cancer Research. 70: 8736-47. PMID 20959481 DOI: 10.1158/0008-5472.CAN-10-0902  0.143
2004 Ashton JC, Zheng Y, Liu P, Darlington CL, Smith PF. Immunohistochemical characterisation and localisation of cannabinoid CB1 receptor protein in the rat vestibular nucleus complex and the effects of unilateral vestibular deafferentation. Brain Research. 1021: 264-71. PMID 15342275 DOI: 10.1016/j.brainres.2004.06.065  0.142
2010 Errington RJ, Brown MR, Silvestre OF, Njoh KL, Chappell SC, Khan IA, Rees P, Wilks SP, Smith PJ, Summers HD. Single cell nanoparticle tracking to model cell cycle dynamics and compartmental inheritance. Cell Cycle (Georgetown, Tex.). 9: 121-30. PMID 20016285  0.141
1975 Smith PA, Case RM. Effects of cholera toxin on cyclic adenosine 3',5'-monophosphate concentration and secretory processes in the exocrine pancreas. Biochimica Et Biophysica Acta. 399: 277-90. PMID 169903 DOI: 10.1016/0304-4165(75)90258-5  0.138
2020 Ghazaly EA, Miraki-Moud F, Smith P, Gnanaranjan C, Koniali L, Oke A, Saied MH, Petty R, Matthews J, Stronge R, Joel SP, Young BD, Gribben J, Taussig DC. Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function. The Journal of Biological Chemistry. PMID 32161116 DOI: 10.1074/Jbc.Ra119.010467  0.137
2007 Bond JA, Gescher AJ, Verschoyle RD, Lemoine NR, Errington R, Wiltshire M, Smith PJ, Wynford-Thomas D. Cytotoxic action of phorbol esters on human pancreatic cancer cells. International Journal of Cancer. Journal International Du Cancer. 121: 1445-54. PMID 17582609 DOI: 10.1002/ijc.22869  0.136
2006 Malarek MS, Evans DJ, Smith PD, Bleeker AR, White JM, Young CG. Pi-acid/pi-base carbonyloxomolybdenum(IV) complexes and their oxomolybdenum(VI/IV) precursors. Inorganic Chemistry. 45: 2209-16. PMID 16499385 DOI: 10.1021/Ic0510314  0.134
2016 Retamal IN, Hernández R, González-Rivas C, Cáceres M, Arancibia R, Romero A, Martínez C, Tobar N, Martínez J, Smith PC. Methylglyoxal and methylglyoxal-modified collagen as inducers of cellular injury in gingival connective tissue cells. Journal of Periodontal Research. PMID 26847600 DOI: 10.1111/jre.12365  0.131
2005 Liu P, Smith PF, Appleton I, Darlington CL, Bilkey DK. Hippocampal nitric oxide synthase and arginase and age-associated behavioral deficits. Hippocampus. 15: 642-55. PMID 15884044 DOI: 10.1002/hipo.20085  0.128
2010 Meng J, Fang B, Liao Y, Chresta CM, Smith PD, Roth JA. Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim. Plos One. 5: e13026. PMID 20885957 DOI: 10.1371/journal.pone.0013026  0.128
2013 Akagi J, Kordon M, Zhao H, Matuszek A, Dobrucki J, Errington R, Smith PJ, Takeda K, Darzynkiewicz Z, Wlodkowic D. Real-time cell viability assays using a new anthracycline derivative DRAQ7®. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 227-34. PMID 23165976 DOI: 10.1002/Cyto.A.22228  0.127
2016 Chen Y, Derkach VA, Smith PA. Loss of Ca(2+)-permeable AMPA receptors in synapses of tonic firing substantia gelatinosa neurons in the chronic constriction injury model of neuropathic pain. Experimental Neurology. PMID 26948545 DOI: 10.1016/J.Expneurol.2016.03.001  0.127
2013 Wlodkowic D, Akagi J, Dobrucki J, Errington R, Smith PJ, Takeda K, Darzynkiewicz Z. Kinetic viability assays using DRAQ7 probe. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 9.41. PMID 23835805 DOI: 10.1002/0471142956.Cy0941S65  0.127
2013 Al-Saraireh YM, Sutherland M, Springett BR, Freiberger F, Ribeiro Morais G, Loadman PM, Errington RJ, Smith PJ, Fukuda M, Gerardy-Schahn R, Patterson LH, Shnyder SD, Falconer RA. Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration. Plos One. 8: e73366. PMID 23951351 DOI: 10.1371/journal.pone.0073366  0.127
2004 Horii A, Masumura C, Smith PF, Darlington CL, Kitahara T, Uno A, Mitani K, Kubo T. Microarray analysis of gene expression in the rat vestibular nucleus complex following unilateral vestibular deafferentation. Journal of Neurochemistry. 91: 975-982. PMID 15525351 DOI: 10.1111/J.1471-4159.2004.02781.X  0.126
2005 Gliddon CM, Darlington CL, Smith PF. GABA(A) receptor subunit expression in the guinea pig vestibular nucleus complex during the development of vestibular compensation. Experimental Brain Research. 166: 71-7. PMID 16021432 DOI: 10.1007/s00221-005-2344-4  0.126
2021 Saarti M, Almukhtar H, Smith PA, Roberts RE. Effect of mitochondrial complex III inhibitors on the regulation of vascular tone in porcine coronary artery. European Journal of Pharmacology. 173917. PMID 33529727 DOI: 10.1016/j.ejphar.2021.173917  0.125
2013 Smith PJ, Furon E, Wiltshire M, Chappell S, Patterson LH, Shnyder SD, Falconer RA, Errington RJ. NCAM polysialylation during adherence transitions: live cell monitoring using an antibody-mimetic EGFP-endosialidase and the viability dye DRAQ7. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 659-71. PMID 23716295 DOI: 10.1002/cyto.a.22306  0.125
2018 Smith PW, Zuccotto F, Bates RH, Martínez-Martínez MS, Read KD, Peet C, Epemolu O. Perspective: Pharmacokinetics of Beta lactam antibiotics: Clues from the past to help discover long acting oral drugs in the future. Acs Infectious Diseases. PMID 30141902 DOI: 10.1021/Acsinfecdis.8B00160  0.124
2002 Smith PJ, Wiltshire M, Davies S, Chin SF, Campbell AK, Errington RJ. DNA damage-induced [Zn(2+)](i) transients: correlation with cell cycle arrest and apoptosis in lymphoma cells. American Journal of Physiology. Cell Physiology. 283: C609-22. PMID 12107071 DOI: 10.1152/ajpcell.00439.2001  0.122
2015 Elmorsy E, Smith PA. Bioenergetic disruption of human micro-vascular endothelial cells by antipsychotics. Biochemical and Biophysical Research Communications. 460: 857-62. PMID 25824037 DOI: 10.1016/j.bbrc.2015.03.122  0.121
2005 Errington RJ, Marquez N, Chappell SC, Wiltshire M, Smith PJ. Time-lapse microscopy approaches to track cell cycle progression at the single-cell level. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 12.4. PMID 18770815 DOI: 10.1002/0471142956.cy1204s31  0.12
2009 Zheng Y, Masumura C, Chung P, Darlington CL, Smith PF. Cell proliferation and survival in the vestibular nucleus following bilateral vestibular deafferentation in the adult rat. Neuroscience Letters. 468: 85-8. PMID 19878706 DOI: 10.1016/j.neulet.2009.10.070  0.12
2012 Little AS, Balmanno K, Sale MJ, Smith PD, Cook SJ. Tumour cell responses to MEK1/2 inhibitors: acquired resistance and pathway remodelling. Biochemical Society Transactions. 40: 73-8. PMID 22260668 DOI: 10.1042/BST20110647  0.118
2007 Khan IA, Husemann P, Campbell L, White NS, White RJ, Smith PJ, Errington RJ. ProgeniDB: a novel cell lineage database for generation associated phenotypic behavior in cell-based assays. Cell Cycle (Georgetown, Tex.). 6: 868-74. PMID 17387278  0.118
2017 Beloueche-Babari M, Wantuch S, Casals Galobart T, Koniordou M, Parkes HG, Arunan V, Chung YL, Eykyn TR, Smith PD, Leach MO. MCT1 inhibitor AZD3965 increases mitochondrial metabolism, facilitating combination therapy and non-invasive magnetic resonance spectroscopy. Cancer Research. PMID 28923861 DOI: 10.1158/0008-5472.Can-16-2686  0.118
2011 Mack CM, Smith PA, Athanacio JR, Xu K, Wilson JK, Reynolds JM, Jodka CM, Lu MG, Parkes DG. Glucoregulatory effects and prolonged duration of action of davalintide: a novel amylinomimetic peptide. Diabetes, Obesity & Metabolism. 13: 1105-13. PMID 21733060 DOI: 10.1111/j.1463-1326.2011.01465.x  0.118
2010 Brown MR, Summers HD, Rees P, Smith PJ, Chappell SC, Errington RJ. Flow-based cytometric analysis of cell cycle via simulated cell populations. Plos Computational Biology. 6: e1000741. PMID 20419143 DOI: 10.1371/journal.pcbi.1000741  0.118
2013 Errington RJ, Chappell SC, Khan IA, Marquez N, Wiltshire M, Griesdoorn VD, Smith PJ. Time-lapse microscopy approaches to track cell cycle and lineage progression at the single-cell level. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit12.4. PMID 23546776 DOI: 10.1002/0471142956.cy1204s64  0.118
1973 Walker R, Smith P. The ionic mechanism for 5-hydroxytryptamine inhibition on retzius cells of the leech Hirudo medicinalis Comparative Biochemistry and Physiology Part a: Physiology. 45: 979-993. DOI: 10.1016/0300-9629(73)90335-6  0.117
2005 Pors K, Plumb JA, Brown R, Teesdale-Spittle P, Searcey M, Smith PJ, Patterson LH. Development of nonsymmetrical 1,4-disubstituted anthraquinones that are potently active against cisplatin-resistant ovarian cancer cells. Journal of Medicinal Chemistry. 48: 6690-5. PMID 16220985 DOI: 10.1021/jm050438f  0.117
2021 van der Westhuyzen R, Mabhula A, Njaria PM, Müller R, Ngumbu Muhunga D, Taylor D, Lawrence N, Njoroge M, Brunschwig C, Moosa A, Singh V, Rao SPS, Manjunatha UH, Smith PW, Warner DF, et al. Benzoheterocyclic Oxime Carbamates Active against : Synthesis, Structure-Activity Relationship, Metabolism, and Biology Triaging. Journal of Medicinal Chemistry. PMID 34138573 DOI: 10.1021/acs.jmedchem.1c00707  0.117
2021 van der Westhuyzen R, Mabhula A, Njaria PM, Müller R, Ngumbu Muhunga D, Taylor D, Lawrence N, Njoroge M, Brunschwig C, Moosa A, Singh V, Rao SPS, Manjunatha UH, Smith PW, Warner DF, et al. Benzoheterocyclic Oxime Carbamates Active against : Synthesis, Structure-Activity Relationship, Metabolism, and Biology Triaging. Journal of Medicinal Chemistry. PMID 34138573 DOI: 10.1021/acs.jmedchem.1c00707  0.117
2013 Smith PJ, Wiltshire M, Chappell SC, Cosentino L, Burns PA, Pors K, Errington RJ. Kinetic analysis of intracellular Hoechst 33342--DNA interactions by flow cytometry: misinterpretation of side population status? Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 161-9. PMID 23136081 DOI: 10.1002/cyto.a.22224  0.117
2004 Smith PF. Therapeutic N-methyl-D-aspartate receptor antagonists: will reality meet expectation? Current Opinion in Investigational Drugs (London, England : 2000). 4: 826-32. PMID 14619404  0.117
2007 Smith PJ, Marquez N, Wiltshire M, Chappell S, Njoh K, Campbell L, Khan IA, Silvestre O, Errington RJ. Mitotic bypass via an occult cell cycle phase following DNA topoisomerase II inhibition in p53 functional human tumor cells. Cell Cycle (Georgetown, Tex.). 6: 2071-81. PMID 17721081  0.117
2017 Lank DB, Xu C, Harrington BA, Morrison RIG, Gratto-Trevor CL, Hicklin PW, Sandercock BK, Smith PA, Kwon E, Rausch J, Pirie Dominix LD, Hamilton DJ, Paquet J, Bliss SE, Neima SG, et al. Long-term continental changes in wing length, but not bill length, of a long-distance migratory shorebird. Ecology and Evolution. 7: 3243-3256. PMID 28480022 DOI: 10.1002/Ece3.2898  0.116
2008 Smith PJ, Wiltshire M, Furon E, Beattie JH, Errington RJ. Impact of overexpression of metallothionein-1 on cell cycle progression and zinc toxicity. American Journal of Physiology. Cell Physiology. 295: C1399-408. PMID 18815222 DOI: 10.1152/ajpcell.00342.2008  0.116
2019 Cavanagh RJ, Smith PA, Stolnik S. Exposure to a non-ionic surfactant induces a response akin to heat-shock apoptosis in intestinal epithelial cells: implications for excipients safety. Molecular Pharmaceutics. PMID 30608696 DOI: 10.1021/acs.molpharmaceut.8b00934  0.116
1981 Smith P, Peterson R. Semi-microscopic analysis of multi-nucleon transfer and the 40Ca(α, p)43Sc reaction Nuclear Physics A. 363: 287-300. DOI: 10.1016/0375-9474(81)90257-8  0.116
2014 Elmorsy E, Elzalabany LM, Elsheikha HM, Smith PA. Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood-brain barrier. Brain Research. 1583: 255-68. PMID 25139421 DOI: 10.1016/J.Brainres.2014.08.011  0.115
2006 Smith PF. Cannabinoids as potential anti-epileptic drugs. Current Opinion in Investigational Drugs (London, England : 2000). 6: 680-5. PMID 16044663  0.115
2016 Bindon KA, Li S, Kassara S, Smith PA. The retention of proanthocyanidin in wine-like solution is conferred by a dynamic interaction between soluble and insoluble grape cell wall components. Journal of Agricultural and Food Chemistry. PMID 27616021 DOI: 10.1021/acs.jafc.6b02900  0.115
2019 Hockley A, Berger JI, Smith PA, Palmer AR, Wallace MN. Nitric oxide regulates the firing rate of neuronal subtypes in the guinea pig ventral cochlear nucleus. The European Journal of Neuroscience. PMID 31494975 DOI: 10.1111/Ejn.14572  0.114
2006 Scott C, Langmead CJ, Clarke KL, Wyman P, Smith PW, Starr KR, Dawson LA, Price GW, Hagan JJ, Watson J. SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist. Neuropharmacology. 50: 984-90. PMID 16546225 DOI: 10.1016/j.neuropharm.2006.01.008  0.114
2003 Liu P, Zheng Y, King J, Darlington CL, Smith PF. Nitric oxide synthase and arginase expression in the vestibular nucleus and hippocampus following unilateral vestibular deafferentation in the rat. Brain Research. 966: 19-25. PMID 12646304 DOI: 10.1016/S0006-8993(02)04146-X  0.113
2010 Baek JH, Zheng Y, Darlington CL, Smith PF. Cannabinoid CB(1) receptor expression and affinity in the rat hippocampus following bilateral vestibular deafferentation. Neuroscience Letters. 487: 330-4. PMID 20974221 DOI: 10.1016/j.neulet.2010.10.050  0.113
2005 Syed N, Smith P, Sullivan A, Spender LC, Dyer M, Karran L, O'Nions J, Allday M, Hoffmann I, Crawford D, Griffin B, Farrell PJ, Crook T. Transcriptional silencing of Polo-like kinase 2 (SNK/PLK2) is a frequent event in B-cell malignancies. Blood. 107: 250-6. PMID 16160013 DOI: 10.1182/BLOOD-2005-03-1194  0.113
2017 Curtis NJ, Mooney L, Hopcroft L, Michopoulos F, Whalley N, Zhong H, Murray C, Logie A, Revill M, Byth KF, Benjamin AD, Firth MA, Green S, Smith PD, Critchlow SE. Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity. Oncotarget. 8: 69219-69236. PMID 29050199 DOI: 10.18632/oncotarget.18215  0.112
2017 Curtis NJ, Mooney L, Hopcroft L, Michopoulos F, Whalley N, Zhong H, Murray C, Logie A, Revill M, Byth KF, Benjamin AD, Firth MA, Green S, Smith PD, Critchlow SE. Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity. Oncotarget. PMID 28599272 DOI: 10.18632/oncotarget.18215  0.112
2003 Marquez N, Chappell SC, Sansom OJ, Clarke AR, Court J, Errington RJ, Smith PJ. Single cell tracking reveals that Msh2 is a key component of an early-acting DNA damage-activated G2 checkpoint. Oncogene. 22: 7642-8. PMID 14576827 DOI: 10.1038/sj.onc.1206876  0.112
2007 Ashton JC, Smith PF. Cannabinoids and cardiovascular disease: the outlook for clinical treatments. Current Vascular Pharmacology. 5: 175-85. PMID 17627561 DOI: 10.2174/157016107781024109  0.111
1983 Hunter M, Smith PA, Case RM. The dependence of fluid secretion by mandibular salivary gland and pancreas on extracellular calcium. Cell Calcium. 4: 307-17. PMID 6685573 DOI: 10.1016/0143-4160(83)90007-6  0.111
2003 Maclennan KM, Zheng Y, Sheard PW, Williams SM, Darlington CL, Smith PF. Adrenalectomy-induced cell death in the dentate gyrus: further characterisation using TUNEL and effects of the Ginkgo biloba extract, EGb 761, and ginkgolide B. Hippocampus. 13: 212-25. PMID 12699329 DOI: 10.1002/hipo.10073  0.11
2007 Smith FL, Gabra BH, Smith PA, Redwood MC, Dewey WL. Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice. Pain. 127: 129-39. PMID 16965856 DOI: 10.1016/j.pain.2006.08.009  0.11
1977 Albinus M, Blair EL, Case RM, Coy DH, Gomez-Pan A, Hirst BH, Reed JD, Schally AV, Shaw B, Smith PA, Smy JR. Comparison of the effect of somatostatin on gastrointestinal function in the conscious and anaesthetized cat and on the isolated cat pancreas. The Journal of Physiology. 269: 77-91. PMID 330838 DOI: 10.1113/jphysiol.1977.sp011893  0.11
2014 Cope CL, Gilley R, Balmanno K, Sale MJ, Howarth KD, Hampson M, Smith PD, Guichard SM, Cook SJ. Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation. Journal of Cell Science. 127: 788-800. PMID 24363449 DOI: 10.1242/jcs.137588  0.11
2013 Akagi J, Skommer J, Matuszek A, Takeda K, Fujimura Y, Khoshmanesh K, Kalantar-Zadeh K, Mitchell A, Errington R, Smith PJ, Darzynkiewicz Z, Wlodkowic D. Multivariate analysis of apoptotic markers versus cell cycle phase in living human cancer cells by microfluidic cytometry. Proceedings of Spie--the International Society For Optical Engineering. 8615. PMID 24386542 DOI: 10.1117/12.2001474  0.11
2016 Russ KA, Elvati P, Parsonage TL, Dews A, Jarvis JA, Ray M, Schneider B, Smith PJ, Williamson PT, Violi A, Philbert MA. C60 fullerene localization and membrane interactions in RAW 264.7 immortalized mouse macrophages. Nanoscale. 8: 4134-44. PMID 26866469 DOI: 10.1039/C5Nr07003A  0.11
2011 Rees P, Brown MR, Summers HD, Holton MD, Errington RJ, Chappell SC, Smith PJ. A transfer function approach to measuring cell inheritance. Bmc Systems Biology. 5: 31. PMID 21342507 DOI: 10.1186/1752-0509-5-31  0.11
2010 Zheng Y, Mason-Parker SE, Logan B, Darlington CL, Smith PF, Abraham WC. Hippocampal synaptic transmission and LTP in vivo are intact following bilateral vestibular deafferentation in the rat. Hippocampus. 20: 461-8. PMID 19533678 DOI: 10.1002/hipo.20645  0.109
2004 Sagar DR, Smith PA, Millns PJ, Smart D, Kendall DA, Chapman V. TRPV1 and CB(1) receptor-mediated effects of the endovanilloid/endocannabinoid N-arachidonoyl-dopamine on primary afferent fibre and spinal cord neuronal responses in the rat. The European Journal of Neuroscience. 20: 175-84. PMID 15245490 DOI: 10.1111/J.1460-9568.2004.03481.X  0.109
2014 Zheng Y, Geddes L, Sato G, Stiles L, Darlington CL, Smith PF. Galvanic vestibular stimulation impairs cell proliferation and neurogenesis in the rat hippocampus but not spatial memory. Hippocampus. 24: 541-52. PMID 24449222 DOI: 10.1002/hipo.22247  0.109
2020 Smith PF, Truchet B, Chaillan FA, Zheng Y, Besnard S. Vestibular Modulation of Long-Term Potentiation and NMDA Receptor Expression in the Hippocampus. Frontiers in Molecular Neuroscience. 13: 140. PMID 32848601 DOI: 10.3389/Fnmol.2020.00140  0.109
2003 Shaaban AM, O'Neill PA, Davies MP, Sibson R, West CR, Smith PH, Foster CS. Declining estrogen receptor-beta expression defines malignant progression of human breast neoplasia. The American Journal of Surgical Pathology. 27: 1502-12. PMID 14657709  0.109
2019 Theil D, Smith P, Huck C, Gilbart Y, Kakarieka A, Leppert D, Rauld C, Schmid C, Baumgartner R, Stuber N, Cordoba F, Dubost V, Darribat K, Jivkov M, Frieauff W, et al. Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys. Frontiers in Immunology. 10: 1340. PMID 31281311 DOI: 10.3389/fimmu.2019.01340  0.109
2006 Buckby LE, Jensen TP, Smith PJ, Empson RM. Network stability through homeostatic scaling of excitatory and inhibitory synapses following inactivity in CA3 of rat organotypic hippocampal slice cultures. Molecular and Cellular Neurosciences. 31: 805-16. PMID 16500111 DOI: 10.1016/J.Mcn.2006.01.009  0.108
2013 Smith PJ, Falconer RA, Errington RJ. Micro-community cytometry: sensing changes in cell health and glycoconjugate expression by imaging and flow cytometry. Journal of Microscopy. 251: 113-22. PMID 23763384 DOI: 10.1111/jmi.12060  0.108
2006 Hossain MM, Smith PG, Wu K, Jin JP. Cytoskeletal tension regulates both expression and degradation of h2-calponin in lung alveolar cells. Biochemistry. 45: 15670-83. PMID 17176089 DOI: 10.1021/bi061718f  0.108
2013 Smith PF, Zheng Y. Principal component analysis suggests subtle changes in glutamate receptor subunit expression in the rat hippocampus following bilateral vestibular deafferentation. Neuroscience Letters. 548: 265-8. PMID 23721785 DOI: 10.1016/j.neulet.2013.05.036  0.108
2016 Smith PJ. Cytometric routes to single cell transcriptomics. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 89: 424-6. PMID 27217223 DOI: 10.1002/cyto.a.22869  0.107
2004 Ashton JC, Appleton I, Darlington CL, Smith PF. Cannabinoid CB1 receptor protein expression in the rat choroid plexus: a possible involvement of cannabinoids in the regulation of cerebrospinal fluid. Neuroscience Letters. 364: 40-2. PMID 15193752 DOI: 10.1016/j.neulet.2004.04.016  0.106
2005 Ashton JC, Appleton I, Darlington CL, Smith PF. Immunohistochemical localization of cannabinoid CB1 receptor in inhibitory interneurons in the cerebellum. Cerebellum (London, England). 3: 222-6. PMID 15686100 DOI: 10.1080/14734220410019011  0.106
2014 Harari D, Kuhn N, Abramovich R, Sasson K, Zozulya AL, Smith P, Schlapschy M, Aharoni R, Köster M, Eilam R, Skerra A, Schreiber G. Enhanced in vivo efficacy of a type I interferon superagonist with extended plasma half-life in a mouse model of multiple sclerosis Journal of Biological Chemistry. 289: 29014-29029. PMID 25193661 DOI: 10.1074/jbc.M114.602474  0.106
2008 Kap YS, Smith P, Jagessar SA, Remarque E, Blezer E, Strijkers GJ, Laman JD, Hintzen RQ, Bauer J, Brok HP, 't Hart BA. Fast progression of recombinant human myelin/oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis in marmosets is associated with the activation of MOG34-56-specific cytotoxic T cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 1326-37. PMID 18209026 DOI: 10.4049/jimmunol.180.3.1326  0.104
2014 Zhang W, Ruvolo VR, Gao C, Zhou L, Bornmann W, Tsao T, Schober WD, Smith P, Guichard S, Konopleva M, Andreeff M. Evaluation of apoptosis induction by concomitant inhibition of MEK, mTOR, and Bcl-2 in human acute myelogenous leukemia cells. Molecular Cancer Therapeutics. 13: 1848-59. PMID 24739393 DOI: 10.1158/1535-7163.Mct-13-0576  0.104
2010 Dry JR, Pavey S, Pratilas CA, Harbron C, Runswick S, Hodgson D, Chresta C, McCormack R, Byrne N, Cockerill M, Graham A, Beran G, Cassidy A, Haggerty C, Brown H, ... ... Smith PD, et al. Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244). Cancer Research. 70: 2264-73. PMID 20215513 DOI: 10.1158/0008-5472.CAN-09-1577  0.104
2015 Doonan CJ, Gourlay C, Nielsen DJ, Ng VW, Smith PD, Evans DJ, George GN, White JM, Young CG. d(1) Oxosulfido-Mo(V) Compounds: First Isolation and Unambiguous Characterization of an Extended Series. Inorganic Chemistry. 54: 6386-96. PMID 26046577 DOI: 10.1021/Acs.Inorgchem.5B00708  0.104
2013 Chung EJ, Urick ME, Kurshan N, Shield W, Asano H, Smith PD, Scroggins BS, Burkeen J, Citrin DE. MEK1/2 inhibition enhances the radiosensitivity of cancer cells by downregulating survival and growth signals mediated by EGFR ligands. International Journal of Oncology. 42: 2028-36. PMID 23588995 DOI: 10.3892/ijo.2013.1890  0.103
2006 Russell NA, Horii A, Smith PF, Darlington CL, Bilkey DK. Lesions of the vestibular system disrupt hippocampal theta rhythm in the rat. Journal of Neurophysiology. 96: 4-14. PMID 16772515 DOI: 10.1152/jn.00953.2005  0.103
2010 Garon EB, Finn RS, Hosmer W, Dering J, Ginther C, Adhami S, Kamranpour N, Pitts S, Desai A, Elashoff D, French T, Smith P, Slamon DJ. Identification of common predictive markers of in vitro response to the Mek inhibitor selumetinib (AZD6244; ARRY-142886) in human breast cancer and non-small cell lung cancer cell lines. Molecular Cancer Therapeutics. 9: 1985-94. PMID 20587667 DOI: 10.1158/1535-7163.Mct-10-0037  0.102
1986 Rafuse PE, Smith PA. Alpha 2-adrenergic hyperpolarization is not involved in slow synaptic inhibition in amphibian sympathetic ganglia. British Journal of Pharmacology. 87: 409-16. PMID 2869815 DOI: 10.1111/J.1476-5381.1986.Tb10831.X  0.101
2014 Ruiz-Garcia Y, Smith PA, Bindon KA. Selective extraction of polysaccharide affects the adsorption of proanthocyanidin by grape cell walls. Carbohydrate Polymers. 114: 102-14. PMID 25263870 DOI: 10.1016/j.carbpol.2014.07.024  0.101
2004 Marquez N, Chappell SC, Sansom OJ, Clarke AR, Teesdale-Spittle P, Errington RJ, Smith PJ. Microtubule stress modifies intra-nuclear location of Msh2 in mouse embryonic fibroblasts. Cell Cycle (Georgetown, Tex.). 3: 662-71. PMID 15044851  0.1
2007 Athanasiou A, Clarke AB, Turner AE, Kumaran NM, Vakilpour S, Smith PA, Bagiokou D, Bradshaw TD, Westwell AD, Fang L, Lobo DN, Constantinescu CS, Calabrese V, Loesch A, Alexander SP, et al. Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications. 364: 131-7. PMID 17931597 DOI: 10.1016/J.Bbrc.2007.09.107  0.1
2013 Bode F, da Silva MA, Smith P, Lorenz CD, McCullen S, Stevens MM, Dreiss CA. Hybrid processes in enzymatically gelled gelatin: impact on , macroscopic properties and cellular response. Soft Matter. 9: 6986-99. PMID 25310528 DOI: 10.1039/C3Sm00125C  0.1
2009 Meng F, Manjula BN, Tsai AG, Cabrales P, Intaglietta M, Smith PK, Prabhakaran M, Acharya SA. Hexa-thiocarbamoyl phenyl PEG5K Hb: vasoactivity and structure: influence of rigidity of the conjugation linkage on the PEGylation induced plasma expander-like solution properties of PEG-Hb adducts. The Protein Journal. 28: 199-212. PMID 19653083 DOI: 10.1007/S10930-009-9185-0  0.1
2008 Meng F, Manjula BN, Smith PK, Acharya SA. PEGylation of human serum albumin: reaction of PEG-phenyl-isothiocyanate with protein. Bioconjugate Chemistry. 19: 1352-60. PMID 18572961 DOI: 10.1021/bc7003878  0.1
2004 Darlington CL, Smith PF. Vestibulotoxicity following aminoglycoside antibiotics and its prevention. Current Opinion in Investigational Drugs (London, England : 2000). 4: 841-6. PMID 14619406  0.099
2017 Zheng Y, Gliddon CM, Aitken P, Stiles L, Machado ML, Philoxene B, Denise P, Smith PF, Besnard S. Effects of Acute Altered Gravity During Parabolic Flight and/or Vestibular Loss on Cell Proliferation in the Rat Dentate Gyrus. Neuroscience Letters. PMID 28645788 DOI: 10.1016/J.Neulet.2017.06.033  0.098
2010 Dawson LA, Langmead CJ, Dada A, Watson JM, Wu Z, de la Flor R, Jones GA, Cluderay JE, Southam E, Murkitt GS, Hill MD, Jones DN, Davies CH, Hagan JJ, Smith PW. In vitro and in vivo comparison of two non-peptide tachykinin NK3 receptor antagonists: Improvements in efficacy achieved through enhanced brain penetration or altered pharmacological characteristics. European Journal of Pharmacology. 627: 106-14. PMID 19879867 DOI: 10.1016/J.Ejphar.2009.10.054  0.098
2017 Wang H, Yapa AS, Kariyawasam NL, Shrestha TB, Wendel SO, Yu J, Pyle M, Basel MT, Malalasekera AP, Toledo Y, Ortega R, Thapa PS, Huang H, Sun SX, Smith PE, et al. Rationally Designed Peptide Nanosponges for Cell-Based Cancer Therapy. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28754467 DOI: 10.1016/J.Nano.2017.07.004  0.098
2005 Smith PF, Horii A, Russell N, Bilkey DK, Zheng Y, Liu P, Kerr DS, Darlington CL. The effects of vestibular lesions on hippocampal function in rats. Progress in Neurobiology. 75: 391-405. PMID 15936135 DOI: 10.1016/j.pneurobio.2005.04.004  0.098
2011 Connolly SC, Smith PG, Fairbank NJ, Lall CA, Cole DJ, Mackinnon JD, Maksym GN. Chronic oscillatory strain induces MLCK associated rapid recovery from acute stretch in airway smooth muscle cells. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 955-63. PMID 21737821 DOI: 10.1152/japplphysiol.00812.2009  0.097
2003 Smith PG, Deng L, Fredberg JJ, Maksym GN. Mechanical strain increases cell stiffness through cytoskeletal filament reorganization. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L456-63. PMID 12704020 DOI: 10.1152/Ajplung.00329.2002  0.097
2012 Smith PG, Tanaka H, Chantry A. A novel co-operative mechanism linking TGFβ and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells. Oncotarget. 3: 518-24. PMID 22643838  0.096
2013 Mart RJ, Errington RJ, Watkins CL, Chappell SC, Wiltshire M, Jones AT, Smith PJ, Allemann RK. BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells. Molecular Biosystems. 9: 2597-603. PMID 23942570 DOI: 10.1039/C3Mb70246D  0.096
2008 Morgan EA, Forootan SS, Adamson J, Foster CS, Fujii H, Igarashi M, Beesley C, Smith PH, Ke Y. Expression of cutaneous fatty acid-binding protein (C-FABP) in prostate cancer: potential prognostic marker and target for tumourigenicity-suppression. International Journal of Oncology. 32: 767-75. PMID 18360704  0.096
2010 Bindon KA, Smith PA, Kennedy JA. Interaction between Grape-Derived Proanthocyanidins and Cell Wall Material. 1. Effect on Proanthocyanidin Composition and Molecular Mass Journal of Agricultural and Food Chemistry. 58: 2520-2528. PMID 20092254 DOI: 10.1021/jf9037453  0.096
2005 Smith PF. Neuroprotection against hypoxia-ischemia by insulin-like growth factor-I (IGF-I). Idrugs : the Investigational Drugs Journal. 6: 1173-7. PMID 14666428  0.096
2014 Bola BM, Chadwick AL, Michopoulos F, Blount KG, Telfer BA, Williams KJ, Smith PD, Critchlow SE, Stratford IJ. Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport. Molecular Cancer Therapeutics. 13: 2805-16. PMID 25281618 DOI: 10.1158/1535-7163.MCT-13-1091  0.096
2019 Nelson N, Lopez-Pelaez M, Palazon A, Poon E, De La Roche M, Barry S, Valge-Archer V, Wilkinson RW, Dovedi SJ, Smith PD. A cell-engineered system to assess tumor cell sensitivity to CD8 T cell-mediated cytotoxicity. Oncoimmunology. 8: 1599635. PMID 31413906 DOI: 10.1080/2162402X.2019.1599635  0.095
2014 Li RW, Kirkland NT, Truong J, Wang J, Smith PN, Birbilis N, Nisbet DR. The influence of biodegradable magnesium alloys on the osteogenic differentiation of human mesenchymal stem cells. Journal of Biomedical Materials Research. Part A. 102: 4346-57. PMID 24677428 DOI: 10.1002/jbm.a.35111  0.095
2015 Gerriets VA, Kishton RJ, Nichols AG, Macintyre AN, Inoue M, Ilkayeva O, Winter PS, Liu X, Priyadharshini B, Slawinska ME, Haeberli L, Huck C, Turka LA, Wood KC, Hale LP, ... Smith PA, et al. Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation. The Journal of Clinical Investigation. 125: 194-207. PMID 25437876 DOI: 10.1172/Jci76012  0.095
2010 Hickinson DM, Klinowska T, Speake G, Vincent J, Trigwell C, Anderton J, Beck S, Marshall G, Davenport S, Callis R, Mills E, Grosios K, Smith P, Barlaam B, Wilkinson RW, et al. AZD8931, an equipotent, reversible inhibitor of signaling by epidermal growth factor receptor, ERBB2 (HER2), and ERBB3: A unique agent for simultaneous ERBB receptor blockade in cancer Clinical Cancer Research. 16: 1159-1169. PMID 20145185 DOI: 10.1158/1078-0432.CCR-09-2353  0.095
2002 Smith PC, Firestein S, Hunt JF. The crystal structure of the olfactory marker protein at 2.3 A resolution. Journal of Molecular Biology. 319: 807-21. PMID 12054872 DOI: 10.1016/S0022-2836(02)00242-5  0.094
2015 Zhang L, Hatzakis E, Nichols RG, Hao R, Correll J, Smith PB, Chiaro CR, Perdew GH, Patterson AD. Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice. Environmental Science & Technology. 49: 8067-77. PMID 26023891 DOI: 10.1021/Acs.Est.5B01389  0.094
2013 Soond SM, Smith PG, Wahl L, Swingler TE, Clark IM, Hemmings AM, Chantry A. Novel WWP2 ubiquitin ligase isoforms as potential prognostic markers and molecular targets in cancer. Biochimica Et Biophysica Acta. 1832: 2127-35. PMID 23938591 DOI: 10.1016/j.bbadis.2013.08.001  0.094
2015 Cai J, Zhang L, Jones RA, Correll JB, Hatzakis E, Smith PB, Gonzalez FJ, Patterson AD. The Anti-Oxidant Drug Tempol Promotes Functional Metabolic Changes in the Gut Microbiota. Journal of Proteome Research. PMID 26696396 DOI: 10.1021/acs.jproteome.5b00957  0.094
2016 Almukhtar H, Garle MJ, Smith PA, Roberts RE. Effect of simvastatin on vascular tone in porcine coronary artery: Potential role of the mitochondria. Toxicology and Applied Pharmacology. PMID 27343404 DOI: 10.1016/j.taap.2016.06.024  0.093
2009 Smith PJ, Furon E, Wiltshire M, Campbell L, Feeney GP, Snyder RD, Errington RJ. ABCG2-associated resistance to Hoechst 33342 and topotecan in a murine cell model with constitutive expression of side population characteristics. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 924-33. PMID 19802874 DOI: 10.1002/cyto.a.20800  0.093
2020 Yuan X, Tang Z, Du R, Yao Z, Cheung SH, Zhang X, Wei J, Zhao Y, Du Y, Liu Y, Hu X, Gong W, Liu Y, Gao Y, Huang Z, ... ... Smith PD, et al. RAF dimer inhibition enhances the antitumor activity of MEK inhibitors in K-RAS mutant tumors. Molecular Oncology. PMID 32336014 DOI: 10.1002/1878-0261.12698  0.093
2014 Boël G, Smith PC, Ning W, Englander MT, Chen B, Hashem Y, Testa AJ, Fischer JJ, Wieden HJ, Frank J, Gonzalez RL, Hunt JF. The ABC-F protein EttA gates ribosome entry into the translation elongation cycle. Nature Structural & Molecular Biology. 21: 143-51. PMID 24389466 DOI: 10.1038/Nsmb.2740  0.093
2015 Smith P, Ho CK, Takagi Y, Djaballah H, Shuman S. Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase. Mbio. 7. PMID 26908574 DOI: 10.1128/Mbio.00058-16  0.093
2019 Choi H, Deng J, Li S, Silk T, Dong L, Brea EJ, Houghton S, Redmond D, Zhong H, Boiarsky J, Akbay EA, Smith PD, Merghoub T, Wong KK, Wolchok JD. Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer. Cell Reports. 27: 806-819.e5. PMID 30995478 DOI: 10.1016/J.Celrep.2019.03.066  0.093
2013 Holder AA, Taylor P, Magnusen AR, Moffett ET, Meyer K, Hong Y, Ramsdale SE, Gordon M, Stubbs J, Seymour LA, Acharya D, Weber RT, Smith PF, Dismukes GC, Ji P, et al. Preliminary anti-cancer photodynamic therapeutic in vitro studies with mixed-metal binuclear ruthenium(II)-vanadium(IV) complexes. Dalton Transactions (Cambridge, England : 2003). 42: 11881-99. PMID 23783642 DOI: 10.1039/C3Dt50547B  0.093
2020 Huarte E, O'Conner RS, Peel MT, Nunez-Cruz S, Leferovich J, Juvekar A, Yang YO, Truong L, Huang T, Naim A, Milone MC, Smith PA. Itacitinib (INCB039110), a JAK1 inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-Cell Therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32998963 DOI: 10.1158/1078-0432.CCR-20-1739  0.093
2014 Qi SD, Smith PD, Choong PF. Nuclear reprogramming and induced pluripotent stem cells: a review for surgeons. Anz Journal of Surgery. 84: 417-23. PMID 24894037 DOI: 10.1111/ans.12419  0.092
2014 Qi SD, Smith PD, Choong PF. Nuclear reprogramming and induced pluripotent stem cells: a review for surgeons. Anz Journal of Surgery. 84: E1-11. PMID 23035845 DOI: 10.1111/j.1445-2197.2012.06282.x  0.092
2022 Smith PJ, McKeown SR, Patterson LH. Targeting DNA topoisomerase IIα (TOP2A) in the hypoxic tumour microenvironment using unidirectional hypoxia-activated prodrugs (uHAPs). Iubmb Life. PMID 35499745 DOI: 10.1002/iub.2619  0.092
2014 Gopal YN, Rizos H, Chen G, Deng W, Frederick DT, Cooper ZA, Scolyer RA, Pupo G, Komurov K, Sehgal V, Zhang J, Patel L, Pereira CG, Broom BM, Mills GB, ... ... Smith PD, et al. Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma. Cancer Research. 74: 7037-47. PMID 25297634 DOI: 10.1158/0008-5472.CAN-14-1392  0.092
2009 Liu P, Smith PF, Darlington CL. Glutamate receptor subunits expression in memory-associated brain structures: regional variations and effects of aging. Synapse (New York, N.Y.). 62: 834-41. PMID 18720514 DOI: 10.1002/syn.20563  0.092
2011 Khan IA, Lupi M, Campbell L, Chappell SC, Brown MR, Wiltshire M, Smith PJ, Ubezio P, Errington RJ. Interoperability of time series cytometric data: a cross platform approach for modeling tumor heterogeneity. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 214-26. PMID 21337698 DOI: 10.1002/cyto.a.21023  0.092
2021 Scuron MD, Fay BL, Connell AJ, Oliver J, Smith PA. The PI3Kδ inhibitor parsaclisib ameliorates pathology and reduces autoantibody formation in preclinical models of systemic lupus erythematosus and Sjӧgren's syndrome. International Immunopharmacology. 98: 107904. PMID 34214886 DOI: 10.1016/j.intimp.2021.107904  0.092
2011 Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, Edwards PA, Smith PD, Cook SJ. A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P. A. W. Edwards, P. D. Smith, S. J. Cook. Science Signaling. 4: er2. PMID 21674991 DOI: 10.1126/scisignal.4170er2  0.091
2018 Hitier M, Sato G, Zhang YF, Besnard S, Smith PF. Effects of Electrical Stimulation of the Rat Vestibular Labyrinth on c-Fos Expression in the Hippocampus. Neuroscience Letters. PMID 29694841 DOI: 10.1016/J.Neulet.2018.04.041  0.091
2003 Phillips TM, Smith P. Analysis of intracellular regulatory proteins by immunoaffinity capillary electrophoresis coupled with laser-induced fluorescence detection. Biomedical Chromatography : Bmc. 17: 182-7. PMID 12717808 DOI: 10.1002/bmc.240  0.091
2004 Smith PJ, Wiltshire M, Errington RJ. DRAQ5 labeling of nuclear DNA in live and fixed cells. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 7.25. PMID 18770802 DOI: 10.1002/0471142956.cy0725s28  0.09
2012 Zhang T, Ploetz EA, Nagy M, Doyle SM, Wickner S, Smith PE, Zolkiewski M. Flexible connection of the N-terminal domain in ClpB modulates substrate binding and the aggregate reactivation efficiency Proteins: Structure, Function and Bioinformatics. 80: 2758-2768. PMID 22890624 DOI: 10.1002/Prot.24159  0.09
2003 Benach J, Chou YT, Fak JJ, Itkin A, Nicolae DD, Smith PC, Wittrock G, Floyd DL, Golsaz CM, Gierasch LM, Hunt JF. Phospholipid-induced monomerization and signal-peptide-induced oligomerization of SecA. The Journal of Biological Chemistry. 278: 3628-38. PMID 12403785 DOI: 10.1074/Jbc.M205992200  0.09
2010 Richter R, Rorbach J, Pajak A, Smith PM, Wessels HJ, Huynen MA, Smeitink JA, Lightowlers RN, Chrzanowska-Lightowlers ZM. A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. The Embo Journal. 29: 1116-25. PMID 20186120 DOI: 10.1038/Emboj.2010.14  0.09
2019 Ponz-Sarvise M, Corbo V, Tiriac H, Engle DD, Frese KK, Oni TE, Hwang CI, Öhlund D, Chio IIC, Baker LA, Filippini D, Wright K, Bapiro TE, Huang PS, Smith PD, et al. Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31492749 DOI: 10.1158/1078-0432.Ccr-19-1398  0.089
2008 Cheung SY, Evans ND, Chappell MJ, Godfrey KR, Smith PJ, Errington RJ. Exploration of the intercellular heterogeneity of topotecan uptake into human breast cancer cells through compartmental modelling. Mathematical Biosciences. 213: 119-34. PMID 18482740 DOI: 10.1016/j.mbs.2008.03.008  0.089
2013 Rao SP, Lakshminarayana SB, Kondreddi RR, Herve M, Camacho LR, Bifani P, Kalapala SK, Jiricek J, Ma NL, Tan BH, Ng SH, Nanjundappa M, Ravindran S, Seah PG, Thayalan P, ... ... Smith PW, et al. Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis. Science Translational Medicine. 5: 214ra168. PMID 24307692 DOI: 10.1126/Scitranslmed.3007355  0.089
2019 Brown AM, Evans RD, Smith PA, Rich LR, Ransom BR. Hypothermic neuroprotection during reperfusion following exposure to aglycemia in central white matter is mediated by acidification. Physiological Reports. 7: e14007. PMID 30834716 DOI: 10.14814/phy2.14007  0.088
2014 Chakravarty AK, Smith P, Jalan R, Shuman S. Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination. Cell Reports. 7: 339-47. PMID 24726365 DOI: 10.1016/J.Celrep.2014.03.034  0.088
2017 Smith PF. Is hippocampal neurogenesis modulated by the sensation of self-motion encoded by the vestibular system? Neuroscience and Biobehavioral Reviews. PMID 28912091 DOI: 10.1016/j.neubiorev.2017.09.013  0.088
2004 Chrzanowska-Lightowlers ZM, Temperley RJ, Smith PM, Seneca SH, Lightowlers RN. Functional polypeptides can be synthesized from human mitochondrial transcripts lacking termination codons. The Biochemical Journal. 377: 725-31. PMID 14585098 DOI: 10.1042/BJ20031556  0.088
2012 Zhang L, Koyyalamudi SR, Jeong SC, Reddy N, Smith PT, Ananthan R, Longvah T. Antioxidant and immunomodulatory activities of polysaccharides from the roots of Sanguisorba officinalis. International Journal of Biological Macromolecules. 51: 1057-62. PMID 22944198 DOI: 10.1016/j.ijbiomac.2012.08.019  0.087
2014 PolaÅ„ski R, Hodgkinson CL, Fusi A, Nonaka D, Priest L, Kelly P, Trapani F, Bishop PW, White A, Critchlow SE, Smith PD, Blackhall F, Dive C, Morrow CJ. Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 926-37. PMID 24277449 DOI: 10.1158/1078-0432.CCR-13-2270  0.087
2020 Morales Torres C, Wu MY, Hobor S, Wainwright EN, Martin MJ, Patel H, Grey W, Grönroos E, Howell S, Carvalho J, Snijders AP, Bustin M, Bonnet D, Smith PD, Swanton C, et al. Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis. Nature Communications. 11: 1792. PMID 32286289 DOI: 10.1038/S41467-020-15615-Z  0.087
2005 Gliddon CM, Darlington CL, Smith PF. GABAergic systems in the vestibular nucleus and their contribution to vestibular compensation. Progress in Neurobiology. 75: 53-81. PMID 15713530 DOI: 10.1016/j.pneurobio.2004.11.001  0.086
2010 Zheng Y, Stiles L, Hamilton E, Smith PF, Darlington CL. The effects of the synthetic cannabinoid receptor agonists, WIN55,212-2 and CP55,940, on salicylate-induced tinnitus in rats. Hearing Research. 268: 145-50. PMID 20630477 DOI: 10.1016/j.heares.2010.05.015  0.086
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI). Neuropharmacology. 48: 648-57. PMID 15814100 DOI: 10.1016/j.neuropharm.2004.12.006  0.086
2005 Heijmans N, Smith PA, Morris-Downes MM, Pryce G, Baker D, Donaldson AVJ, Hart B', Amor S. Encephalitogenic and tolerogenic potential of altered peptide ligands of MOG and PLP in Biozzi ABH mice Journal of Neuroimmunology. 167: 23-33. PMID 16054237 DOI: 10.1016/J.Jneuroim.2005.06.005  0.086
2019 Huck C, Leppert D, Wegert V, Schmid C, Dunn R, Weckbecker G, Smith PA. Low-Dose Subcutaneous Anti-CD20 Treatment Depletes Disease Relevant B Cell Subsets and Attenuates Neuroinflammation. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 31435856 DOI: 10.1007/s11481-019-09872-z  0.086
2011 Smith PJ, Radbruch A. Cyto 2011 - overview of the XXVI ISAC Congress Proceedings Issue of Cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 325-7. PMID 21520398 DOI: 10.1002/Cyto.A.21069  0.086
2007 Smith P, Nicholson LJ, Syed N, Payne A, Hiller L, Garrone O, Occelli M, Gasco M, Crook T. Epigenetic inactivation implies independent functions for insulin-like growth factor binding protein (IGFBP)-related protein 1 and the related IGFBPL1 in inhibiting breast cancer phenotypes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4061-8. PMID 17634530 DOI: 10.1158/1078-0432.CCR-06-3052  0.086
2004 Sullivan A, Syed N, Gasco M, Bergamaschi D, Trigiante G, Attard M, Hiller L, Farrell PJ, Smith P, Lu X, Crook T. Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo. Oncogene. 23: 3328-37. PMID 15077186 DOI: 10.1038/sj.onc.1207428  0.086
2020 Gee S, Nelson N, Bornot A, Carter N, Cuomo ME, Dovedi SJ, Smith PD, Gianni D, Baker DJ. Developing an Arrayed CRISPR-Cas9 Co-Culture Screen for Immuno-Oncology Target ID. Slas Discovery : Advancing Life Sciences R & D. 2472555220916457. PMID 32375580 DOI: 10.1177/2472555220916457  0.086
2022 Merchant R, Galligan C, Munegowda MA, Pearce LB, Lloyd P, Smith P, Merchant F, To MD. Fine-tuned long-acting interleukin-2 superkine potentiates durable immune responses in mice and non-human primate. Journal For Immunotherapy of Cancer. 10. PMID 35058325 DOI: 10.1136/jitc-2021-003155  0.085
2018 Stiles L, Zheng Y, Smith PF. The effects of electrical stimulation of the peripheral vestibular system on neurochemical release in the rat striatum. Plos One. 13: e0205869. PMID 30372453 DOI: 10.1371/journal.pone.0205869  0.085
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Protein Kinase A activity is increased in mouse lumbar spinal cord but not brain following morphine antinociceptive tolerance for 15 days. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 52: 204-10. PMID 16026714 DOI: 10.1016/j.phrs.2005.03.004  0.085
2015 Bartholomeusz C, Xie X, Pitner MK, Kondo K, Dadbin A, Lee J, Saso H, Smith PD, Dalby KN, Ueno NT. MEK inhibitor selumetinib (AZD6244; ARRY-142886) prevents lung metastasis in a triple-negative breast cancer xenograft model. Molecular Cancer Therapeutics. PMID 26384399 DOI: 10.1158/1535-7163.Mct-15-0243  0.085
2002 Darlington CL, Dutia MB, Smith PF. The contribution of the intrinsic excitability of vestibular nucleus neurons to recovery from vestibular damage. The European Journal of Neuroscience. 15: 1719-27. PMID 12081651 DOI: 10.1046/j.1460-9568.2002.02024.x  0.085
2012 Tonkin JA, Rees P, Brown MR, Errington RJ, Smith PJ, Chappell SC, Summers HD. Automated cell identification and tracking using nanoparticle moving-light-displays. Plos One. 7: e40835. PMID 22829889 DOI: 10.1371/journal.pone.0040835  0.085
2015 Willemse H, Theodoratos A, Smith PN, Dulhunty AF. Unexpected dependence of RyR1 splice variant expression in human lower limb muscles on fiber-type composition. Pflugers Archiv : European Journal of Physiology. PMID 26438192 DOI: 10.1007/s00424-015-1738-9  0.085
2003 Davis T, Singhrao SK, Wyllie FS, Haughton MF, Smith PJ, Wiltshire M, Wynford-Thomas D, Jones CJ, Faragher RG, Kipling D. Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms. Journal of Cell Science. 116: 1349-57. PMID 12615976 DOI: 10.1242/jcs.00331  0.085
2021 Huarte E, Peel M, Juvekar A, Dubé P, Sarah S, Stephens L, Stewart B, Long B, Czerniak P, Oliver J, Smith P. Ruxolitinib, a JAK1/JAK2 selective inhibitor, ameliorates acute and chronic steroid-refractory GvHD mouse models. Immunotherapy. PMID 34184542 DOI: 10.2217/imt-2021-0013  0.084
2015 Lee JH, Hornik CP, Testoni D, Laughon MM, Cotten CM, Maldonado RS, Belcastro MR, Clark RH, Smith PB. Insulin, Hyperglycemia, and Severe Retinopathy of Prematurity in Extremely Low-Birth-Weight Infants. American Journal of Perinatology. PMID 26485249 DOI: 10.1055/s-0035-1565999  0.084
2006 Njoh KL, Patterson LH, Zloh M, Wiltshire M, Fisher J, Chappell S, Ameer-Beg S, Bai Y, Matthews D, Errington RJ, Smith PJ. Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 805-14. PMID 16969814 DOI: 10.1002/cyto.a.20308  0.084
2013 Bindon KA, Smith PA. Comparison of the affinity and selectivity of insoluble fibres and commercial proteins for wine proanthocyanidins. Food Chemistry. 136: 917-28. PMID 23122145 DOI: 10.1016/j.foodchem.2012.08.016  0.084
2015 Liu DY, Smith PM, Barton DA, Day DA, Overall RL. Characterisation of Arabidopsis calnexin 1 and calnexin 2 in the endoplasmic reticulum and at plasmodesmata. Protoplasma. PMID 26680228 DOI: 10.1007/S00709-015-0921-3  0.084
2002 Nicholson M, King J, Smith PF, Darlington CL. Vestibulo-ocular, optokinetic and postural function in diabetes mellitus. Neuroreport. 13: 153-7. PMID 11924879 DOI: 10.1097/00001756-200201210-00035  0.084
2016 Clarke DJ, Murray E, Faktor J, Mohtar A, Vojtesek B, MacKay CL, Smith PL, Hupp TR. Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond. Biochimica Et Biophysica Acta. PMID 26876500 DOI: 10.1016/j.bbapap.2016.02.011  0.084
2004 Smith FL, Smith PA, Dewey WL, Javed RR. Effects of mGlu1 and mGlu5 metabotropic glutamate antagonists to reverse morphine tolerance in mice. European Journal of Pharmacology. 492: 137-42. PMID 15178357 DOI: 10.1016/j.ejphar.2004.03.055  0.083
2021 Humphreys LM, Smith P, Chen Z, Fouad S, D'Angiolella V. The role of E3 ubiquitin ligases in the development and progression of glioblastoma. Cell Death and Differentiation. PMID 33432111 DOI: 10.1038/s41418-020-00696-6  0.083
2019 Sale MJ, Balmanno K, Saxena J, Ozono E, Wojdyla K, McIntyre RE, Gilley R, Woroniuk A, Howarth KD, Hughes G, Dry JR, Arends MJ, Caro P, Oxley D, Ashton S, ... ... Smith PD, et al. MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAF amplification whereas KRAS amplification promotes EMT-chemoresistance. Nature Communications. 10: 2030. PMID 31048689 DOI: 10.1038/S41467-019-09438-W  0.083
2016 Nilar SH, Lakshminarayana SB, Ma NL, Keller TH, Blasco F, Smith PW. Artificial Neural Network Analysis of Pharmacokinetic and Toxicity Properties of Lead Molecules for Dengue Fever, Tuberculosis and Malaria. Current Computer-Aided Drug Design. PMID 26777113  0.083
2012 Zheng Y, Balabhadrapatruni S, Baek JH, Chung P, Gliddon C, Zhang M, Darlington CL, Napper R, Strupp M, Brandt T, Smith PF. The effects of bilateral vestibular loss on hippocampal volume, neuronal number, and cell proliferation in rats. Frontiers in Neurology. 3: 20. PMID 22403568 DOI: 10.3389/fneur.2012.00020  0.082
2011 Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, Edwards PA, Smith PD, Cook SJ. Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells. Science Signaling. 4: ra17. PMID 21447798 DOI: 10.1126/scisignal.2001752  0.082
2015 Mollanazar NK, Smith PK, Yosipovitch G. Mediators of Chronic Pruritus in Atopic Dermatitis: Getting the Itch Out? Clinical Reviews in Allergy & Immunology. PMID 25931325 DOI: 10.1007/s12016-015-8488-5  0.082
2016 Feng S, Shao L, Castro P, Coleman I, Nelson PS, Smith PD, Davies BR, Ittmann M. Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors. Oncotarget. PMID 28008155 DOI: 10.18632/oncotarget.14049  0.082
2004 Javed RR, Dewey WL, Smith PA, Smith FL. PKC and PKA inhibitors reverse tolerance to morphine-induced hypothermia and supraspinal analgesia in mice. European Journal of Pharmacology. 492: 149-57. PMID 15178359 DOI: 10.1016/j.ejphar.2004.03.061  0.082
2016 Unciuleac MC, Smith PC, Shuman S. Crystal structure and biochemical characterization of a Mycobacterium smegmatis AAA-type nucleoside triphosphatase phosphohydrolase (Msm0858). Journal of Bacteriology. PMID 26953339 DOI: 10.1128/Jb.00905-15  0.082
2004 Evans ND, Errington RJ, Shelley M, Feeney GP, Chapman MJ, Godfrey KR, Smith PJ, Chappell MJ. A mathematical model for the in vitro kinetics of the anti-cancer agent topotecan. Mathematical Biosciences. 189: 185-217. PMID 15094319 DOI: 10.1016/j.mbs.2004.01.007  0.081
2006 Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell. 126: 121-34. PMID 16839881 DOI: 10.1016/J.Cell.2006.05.034  0.081
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Chronic Delta9-tetrahydrocannabinol treatment produces antinociceptive tolerance in mice without altering protein kinase A activity in mouse brain and spinal cord. Biochemical Pharmacology. 70: 152-60. PMID 15913565 DOI: 10.1016/j.bcp.2005.04.008  0.081
2021 Smith P, Owen DM, Lorenz CD, Makarova M. Asymmetric glycerophospholipids impart distinctive biophysical properties to lipid bilayers. Biophysical Journal. PMID 33705758 DOI: 10.1016/j.bpj.2021.02.046  0.081
2020 Verma V, Jafarzadeh N, Boi S, Kundu S, Jiang Z, Fan Y, Lopez J, Nandre R, Zeng P, Alolaqi F, Ahmad S, Gaur P, Barry ST, Valge-Archer VE, Smith PD, et al. MEK inhibition reprograms CD8 T lymphocytes into memory stem cells with potent antitumor effects. Nature Immunology. PMID 33230330 DOI: 10.1038/s41590-020-00818-9  0.081
2006 Smith PF, Ashton JC, Darlington CL. The endocannabinoid system: A new player in the neurochemical control of vestibular function? Audiology & Neuro-Otology. 11: 207-12. PMID 16601324 DOI: 10.1159/000092588  0.081
2017 Wilson LJ, Linley A, Hammond DE, Hood FE, Coulson JM, MacEwan DJ, Ross SJ, Slupsky JR, Smith PD, Eyers PA, Prior IA. New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome. Cancer Research. PMID 29254998 DOI: 10.1158/0008-5472.CAN-17-2291  0.081
2017 Aitken P, Zheng Y, Smith PF. Effects of bilateral vestibular deafferentation in rat on hippocampal theta response to somatosensory stimulation, acetylcholine release, and cholinergic neurons in the pedunculopontine tegmental nucleus. Brain Structure & Function. PMID 28349227 DOI: 10.1007/s00429-017-1407-1  0.08
2003 Smith PG, Roy C, Zhang YN, Chauduri S. Mechanical stress increases RhoA activation in airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology. 28: 436-42. PMID 12654632 DOI: 10.1165/rcmb.4754  0.08
2015 Eberlein CA, Stetson D, Markovets AA, Al-Kadhimi KJ, Lai Z, Fisher PR, Meador CB, Spitzler P, Ichihara E, Ross SJ, Ahdesmaki MJ, Ahmed A, Ratcliffe LE, O'Brien EL, Barnes CH, ... ... Smith PD, et al. Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models. Cancer Research. 75: 2489-500. PMID 25870145 DOI: 10.1158/0008-5472.Can-14-3167  0.08
2015 Rule S, Smith P, Johnson PW, Bolam S, Follows G, Gambell J, Hillmen P, Jack A, Johnson S, Kirkwood AA, Kruger A, Pocock C, Seymour JF, Toncheva M, Walewski J, et al. The addition of Rituximab to Fludarabine and Cyclophosphamide chemotherapy results in a significant improvement in overall survival in patients with newly diagnosed mantle cell lymphoma: results of a randomized UK National Cancer Research Institute trial. Haematologica. PMID 26611473 DOI: 10.3324/haematol.2015.128710  0.08
2009 Cox N, Ho FM, Pewnim N, Steffen R, Smith PJ, Havelius KG, Hughes JL, Debono L, Styring S, Krausz E, Pace RJ. The S(1) split signal of photosystem II; a tyrosine-manganese coupled interaction. Biochimica Et Biophysica Acta. 1787: 882-9. PMID 19362068 DOI: 10.1016/J.Bbabio.2009.03.023  0.08
2022 Hamm G, Maglennon G, Williamson B, Macdonald R, Doherty A, Jones S, Harris J, Blades J, Harmer AR, Barton P, Rawlins PB, Smith P, Winter-Holt J, McMurray L, Johansson J, et al. Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment. Archives of Toxicology. PMID 34973110 DOI: 10.1007/s00204-021-03197-8  0.08
2015 Zheng Y, Smithies H, Aitken P, Gliddon C, Stiles L, Darlington CL, Smith PF. Cell proliferation in the cochlear nucleus following acoustic trauma in rat Neuroscience. 303: 524-534. DOI: 10.1016/j.neuroscience.2015.07.033  0.08
2012 Holt SV, Logie A, Davies BR, Alferez D, Runswick S, Fenton S, Chresta CM, Gu Y, Zhang J, Wu YL, Wilkinson RW, Guichard SM, Smith PD. Enhanced apoptosis and tumor growth suppression elicited by combination of MEK (selumetinib) and mTOR kinase inhibitors (AZD8055). Cancer Research. 72: 1804-13. PMID 22271687 DOI: 10.1158/0008-5472.CAN-11-1780  0.08
2005 Doherty M, Smith P, Hughes M, Davison R. Caffeine lowers perceptual response and increases power output during high-intensity cycling. Journal of Sports Sciences. 22: 637-43. PMID 15370494 DOI: 10.1080/02640410310001655741  0.08
2016 Balabhadrapatruni S, Zheng Y, Napper R, Smith PF. Basal Dendritic Length is Reduced in the Rat Hippocampus Following Bilateral Vestibular Deafferentation. Neurobiology of Learning and Memory. PMID 26976094 DOI: 10.1016/j.nlm.2016.03.009  0.079
2002 Marchetti B, Morale MC, Brouwer J, Tirolo C, Testa N, Caniglia S, Barden N, Amor S, Smith PA, Dijkstra CD. Exposure to a dysfunctional glucocorticoid receptor from early embryonic life programs the resistance to experimental autoimmune encephalomyelitis via nitric oxide-induced immunosuppression. Journal of Immunology (Baltimore, Md. : 1950). 168: 5848-59. PMID 12023389 DOI: 10.4049/jimmunol.168.11.5848  0.079
2005 Gliddon CM, Darlington CL, Smith PF. Effects of chronic infusion of a GABAA receptor agonist or antagonist into the vestibular nuclear complex on vestibular compensation in the guinea pig. The Journal of Pharmacology and Experimental Therapeutics. 313: 1126-35. PMID 15687370 DOI: 10.1124/jpet.104.082172  0.079
2017 Aitken P, Zheng Y, Smith PF. The Modulation of Hippocampal Theta Rhythm by the Vestibular System. Journal of Neurophysiology. jn.00548.2017. PMID 29167325 DOI: 10.1152/jn.00548.2017  0.079
2010 Pilla M, Andreoli M, Tessari M, Delle-Fratte S, Roth A, Butler S, Brown F, Shah P, Bettini E, Cavallini P, Benedetti R, Minick D, Smith P, Tehan B, D'Alessandro P, et al. The identification of novel orally active mGluR5 antagonist GSK2210875. Bioorganic & Medicinal Chemistry Letters. 20: 7521-4. PMID 21051228 DOI: 10.1016/j.bmcl.2010.09.120  0.079
2017 Poon E, Mullins S, Watkins A, Williams GS, Koopmann JO, Di Genova G, Cumberbatch M, Veldman-Jones M, Grosskurth SE, Sah V, Schuller A, Reimer C, Dovedi SJ, Smith PD, Stewart R, et al. The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment. Journal For Immunotherapy of Cancer. 5: 63. PMID 28815043 DOI: 10.1186/s40425-017-0268-8  0.079
2017 Poon E, Mullins S, Watkins A, Williams GS, Koopmann JO, Di Genova G, Cumberbatch M, Veldman-Jones M, Grosskurth SE, Sah V, Schuller A, Reimer C, Dovedi SJ, Smith PD, Stewart R, et al. The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment. Journal For Immunotherapy of Cancer. 5: 63. PMID 28807001 DOI: 10.1186/S40425-017-0268-8  0.079
2015 Khraiwesh M, Leed S, Roncal N, Johnson J, Sciotti R, Smith P, Read L, Paris R, Hudson T, Hickman M, Grogl M. Antileishmanial Activity of Compounds Derived from the Medicines for Malaria Venture Open Access Box Against Intracellular Leishmania major Amastigotes. The American Journal of Tropical Medicine and Hygiene. PMID 26503273 DOI: 10.4269/Ajtmh.15-0448  0.079
2002 Smith PJ, Peterson S, Masters VM, Wydrzynski T, Styring S, Krausz E, Pace RJ. Magneto-optical measurements of the pigments in fully active photosystem II core complexes from plants. Biochemistry. 41: 1981-9. PMID 11827545 DOI: 10.1021/Bi0111202  0.079
2015 Hancox U, Cosulich S, Hanson L, Trigwell C, Lenaghan C, Ellston R, Dry H, Crafter C, Barlaam B, Fitzek M, Smith PD, Ogilvie D, D'Cruz C, Castriotta L, Wedge SR, et al. Inhibition of PI3Kβ signaling with AZD8186 inhibits growth of PTEN-deficient breast and prostate tumors alone and in combination with docetaxel. Molecular Cancer Therapeutics. 14: 48-58. PMID 25398829 DOI: 10.1158/1535-7163.MCT-14-0406  0.078
2018 Sewell F, Ragan I, Indans I, Marczylo T, Stallard N, Griffiths D, Holmes T, Smith P, Horgan G. An evaluation of the fixed concentration procedure for assessment of acute inhalation toxicity. Regulatory Toxicology and Pharmacology : Rtp. PMID 29309809 DOI: 10.1016/j.yrtph.2018.01.001  0.078
2012 Zheng Y, McNamara E, Stiles L, Darlington CL, Smith PF. Evidence that Memantine Reduces Chronic Tinnitus Caused by Acoustic Trauma in Rats. Frontiers in Neurology. 3: 127. PMID 23015804 DOI: 10.3389/fneur.2012.00127  0.078
2002 Smith PC, Karpowich N, Millen L, Moody JE, Rosen J, Thomas PJ, Hunt JF. ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Molecular Cell. 10: 139-49. PMID 12150914 DOI: 10.1016/S1097-2765(02)00576-2  0.078
2010 Samai P, Smith P, Shuman S. Structure of a CRISPR-associated protein Cas2 from Desulfovibrio vulgaris. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1552-6. PMID 21139194 DOI: 10.1107/S1744309110039801  0.078
2015 Bornancin F, Renner F, Touil R, Sic H, Kolb Y, Touil-Allaoui I, Rush JS, Smith PA, Bigaud M, Junker-Walker U, Burkhart C, Dawson J, Niwa S, Katopodis A, Nuesslein-Hildesheim B, et al. Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 3723-34. PMID 25762782 DOI: 10.4049/jimmunol.1402254  0.078
2015 Hixson JL, Bindon KA, Smith PA. Evaluation of Direct Phloroglucinolysis and Colorimetric Depolymerization Assays and Their Applicability for Determining Condensed Tannins in Grape Marc. Journal of Agricultural and Food Chemistry. PMID 26551987 DOI: 10.1021/acs.jafc.5b04207  0.078
2009 Nicholson LJ, Smith PR, Hiller L, Szlosarek PW, Kimberley C, Sehouli J, Koensgen D, Mustea A, Schmid P, Crook T. Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum-induced cell death but collateral sensitivity to arginine auxotrophy in ovarian cancer. International Journal of Cancer. 125: 1454-63. PMID 19533750 DOI: 10.1002/ijc.24546  0.077
2015 Richards SD, Baker CMJ, Bird AJ, Cowan P, Davies N, Dobson GP, Fry TC, Kyrieleis A, Smith PN. MONK and MCBEND: Current status and recent developments Annals of Nuclear Energy. 82: 63-73. DOI: 10.1016/j.anucene.2014.07.054  0.077
2015 Zheng Y, McPherson K, Reid P, Smith PF. The anti-inflammatory selective melanocortin receptor subtype 4 agonist, RO27-3225, fails to prevent acoustic trauma-induced tinnitus in rats. European Journal of Pharmacology. 761: 206-210. PMID 25977231 DOI: 10.1016/j.ejphar.2015.05.007  0.077
2005 Ashton JC, Khalessi A, Kapoor M, Clarkson A, Sammut IA, Darlington CL, Smith PF. Characterization of mitochondrial respiratory chain energetics in the vestibular nucleus complex Acta Oto-Laryngologica. 125: 422-425. PMID 15823815 DOI: 10.1080/00016480410024659  0.077
2014 Jin L, Smith P, Noble CJ, Stranger R, Hanson GR, Pace RJ. Electronic structure of the oxygen evolving complex in photosystem II, as revealed by 55Mn Davies ENDOR studies at 2.5 K. Physical Chemistry Chemical Physics : Pccp. 16: 7799-812. PMID 24643307 DOI: 10.1039/c3cp55189j  0.077
2003 James AM, Blaikie FH, Smith RA, Lightowlers RN, Smith PM, Murphy MP. Specific targeting of a DNA-alkylating reagent to mitochondria. Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide. European Journal of Biochemistry. 270: 2827-36. PMID 12823553 DOI: 10.1046/j.1432-1033.2003.03660.x  0.077
2016 Delpuech O, Rooney C, Mooney L, Baker D, Shaw R, Dymond M, Wang D, Zhang P, Cross S, Veldman-Jones MH, Wilson J, Davies BR, Dry JR, Kilgour E, Smith PD. Identification of pharmacodynamic transcript biomarkers in response to FGFR inhibition by AZD4547. Molecular Cancer Therapeutics. PMID 27550940 DOI: 10.1158/1535-7163.MCT-16-0297  0.077
2015 Thelingwani R, Leandersson C, Bonn B, Smith P, Chibale K, Masimirembwa C. Characterisation of artemisinin-chloroquinoline hybrids for potential metabolic liabilities. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-7. PMID 26338168 DOI: 10.3109/00498254.2015.1070975  0.077
2005 Ellmerich S, Mycko M, Takacs K, Waldner H, Wahid FN, Boyton RJ, King RH, Smith PA, Amor S, Herlihy AH, Hewitt RE, Jutton M, Price DA, Hafler DA, Kuchroo VK, et al. High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model. Journal of Immunology (Baltimore, Md. : 1950). 174: 1938-46. PMID 15699121 DOI: 10.4049/Jimmunol.174.4.1938  0.077
2003 Arsköld SP, Masters VM, Prince BJ, Smith PJ, Pace RJ, Krausz E. Optical spectra of synechocystis and spinach photosystem II preparations at 1.7 K: identification of the D1-pheophytin energies and stark shifts. Journal of the American Chemical Society. 125: 13063-74. PMID 14570479 DOI: 10.1021/ja034548s  0.077
2021 Hitier M, Zhang YF, Sato G, Besnard S, Zheng Y, Smith PF. Stratification of hippocampal electrophysiological activation evoked by selective electrical stimulation of different angular and linear acceleration sensors in the rat peripheral vestibular system. Hearing Research. 403: 108173. PMID 33465547 DOI: 10.1016/j.heares.2021.108173  0.077
2018 Beckmann N, Giorgetti E, Neuhaus A, Zurbruegg S, Accart N, Smith P, Perdoux J, Perrot L, Nash M, Desrayaud S, Wipfli P, Frieauff W, Shimshek DR. Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945. Acta Neuropathologica Communications. 6: 9. PMID 29448957 DOI: 10.1186/s40478-018-0510-8  0.077
2019 Gupta A, Towers C, Willenbrock F, Brant R, Hodgson DR, Sharpe A, Smith P, Cutts A, Schuh A, Asher R, Myers K, Love S, Collins L, Wise A, Middleton MR, et al. Dual-specificity protein phosphatase DUSP4 regulates response to MEK inhibition in BRAF wild-type melanoma. British Journal of Cancer. PMID 31839677 DOI: 10.1038/s41416-019-0673-5  0.076
2002 King J, Zheng Y, Liu P, Darlington CL, Smith PF. NMDA and AMPA receptor subunit protein expression in the rat vestibular nucleus following unilateral labyrinthectomy. Neuroreport. 13: 1541-5. PMID 12218702 DOI: 10.1097/00001756-200208270-00011  0.076
2005 Arsköld SP, Smith PJ, Shen JR, Pace RJ, Krausz E. Key cofactors of photosystem II cores from four organisms identified by 1.7-K absorption, CD and MCD. Photosynthesis Research. 84: 309-16. PMID 16049791 DOI: 10.1007/S11120-005-2135-6  0.076
2012 Zhang J, Zhang L, Su X, Li M, Xie L, Malchers F, Fan S, Yin X, Xu Y, Liu K, Dong Z, Zhu G, Qian Z, Tang L, Schöttle J, ... ... Smith PD, et al. Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6658-67. PMID 23082000 DOI: 10.1158/1078-0432.CCR-12-2694  0.076
2021 Smith P, Clay RP. The identity of Félix de Azara's "Alondras" and implications for Neotropical pipit nomenclature (Aves, Motacillidae: Anthus). Zootaxa. 4942: zootaxa.4942.1.6. PMID 33756914 DOI: 10.11646/zootaxa.4942.1.6  0.076
2013 Das U, Wang LK, Smith P, Shuman S. Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkp•hen1 RNA repair system. Biochemistry. 52: 4734-43. PMID 23721485 DOI: 10.1021/Bi400412X  0.076
2003 Russell NA, Horii A, Smith PF, Darlington CL, Bilkey DK. Long-term effects of permanent vestibular lesions on hippocampal spatial firing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6490-8. PMID 12878690 DOI: 10.1523/Jneurosci.23-16-06490.2003  0.076
2003 Liu P, Bilkey DK, Darlington CL, Smith PF. Cannabinoid CB1 receptor protein expression in the rat hippocampus and entorhinal, perirhinal, postrhinal and temporal cortices: regional variations and age-related changes. Brain Research. 979: 235-9. PMID 12850592 DOI: 10.1016/S0006-8993(03)02872-5  0.075
2004 Feber A, Clark J, Goodwin G, Dodson AR, Smith PH, Fletcher A, Edwards S, Flohr P, Falconer A, Roe T, Kovacs G, Dennis N, Fisher C, Wooster R, Huddart R, et al. Amplification and overexpression of E2F3 in human bladder cancer. Oncogene. 23: 1627-30. PMID 14716298 DOI: 10.1038/sj.onc.1207274  0.075
2009 Eve HE, Linch D, Qian W, Ross M, Seymour JF, Smith P, Stevens L, Rule SA. Toxicity of fludarabine and cyclophosphamide with or without rituximab as initial therapy for patients with previously untreated mantle cell lymphoma: results of a randomised phase II study. Leukemia & Lymphoma. 50: 211-5. PMID 19197729 DOI: 10.1080/10428190802688509  0.075
2013 McRae JM, Schulkin A, Kassara S, Holt HE, Smith PA. Sensory properties of wine tannin fractions: implications for in-mouth sensory properties. Journal of Agricultural and Food Chemistry. 61: 719-27. PMID 23289627 DOI: 10.1021/jf304239n  0.075
2020 Flemington V, Davies EJ, Robinson D, Sandin LC, Delpuech O, Zhang P, Hanson L, Farrington P, Bell S, Falenta K, Gibbons FD, Lindsay N, Smith A, Wilson J, Roberts K, ... ... Smith PD, et al. AZD0364 is a potent and selective ERK1/2 inhibitor which enhances anti-tumour activity in KRAS mutant tumour models when combined with the MEK inhibitor selumetinib. Molecular Cancer Therapeutics. PMID 33273059 DOI: 10.1158/1535-7163.MCT-20-0002  0.075
1983 Atkinson S, Smith PA, Taylor JJ, Kendall-Taylor P. Specific epidermal growth factor receptors on porcine thyroid cell membranes. Febs Letters. 153: 88-92. PMID 6298011 DOI: 10.1016/0014-5793(83)80124-0  0.075
2021 Finlay MRV, Barton P, Bickerton S, Bista M, Colclough N, Cross DAE, Evans L, Floc'h N, Gregson C, Guérot CM, Hargreaves D, Kang X, Lenz EM, Li X, Liu Y, ... ... Smith PD, et al. Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance. Journal of Medicinal Chemistry. PMID 34491761 DOI: 10.1021/acs.jmedchem.1c01055  0.075
2015 Wooten KJ, Blackwell BR, McEachran AD, Mayer GD, Smith PN. Airborne particulate matter collected near beef cattle feedyards induces androgenic and estrogenic activity in vitro Agriculture, Ecosystems and Environment. 203: 29-35. DOI: 10.1016/J.Agee.2015.01.016  0.075
2010 Bindon KA, Smith PA, Holt H, Kennedy JA. Interaction between grape-derived proanthocyanidins and cell wall material. 2. Implications for vinification. Journal of Agricultural and Food Chemistry. 58: 10736-46. PMID 20845924 DOI: 10.1021/jf1022274  0.074
2010 D'Alessandro PL, Corti C, Roth A, Ugolini A, Sava A, Montanari D, Bianchi F, Garland SL, Powney B, Koppe EL, Rocheville M, Osborne G, Perez P, de la Fuente J, De Los Frailes M, ... Smith PW, et al. The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2. Bioorganic & Medicinal Chemistry Letters. 20: 759-62. PMID 20005096 DOI: 10.1016/j.bmcl.2009.11.032  0.074
2015 Stringer T, Taylor D, Guzgay H, Shokar A, Au A, Smith PJ, Hendricks DT, Land KM, Egan TJ, Smith GS. Polyamine quinoline rhodium complexes: synthesis and pharmacological evaluation as antiparasitic agents against Plasmodium falciparum and Trichomonas vaginalis. Dalton Transactions (Cambridge, England : 2003). PMID 26226082 DOI: 10.1039/c5dt02378e  0.074
2015 Herstein JJ, Biddinger PD, Kraft CS, Saiman L, Gibbs SG, Le AB, Smith PW, Hewlett AL, Lowe JJ. Current Capabilities and Capacity of Ebola Treatment Centers in the United States. Infection Control and Hospital Epidemiology. 1-6. PMID 26641267 DOI: 10.1017/Ice.2015.300  0.074
2013 Delarasse C, Smith P, Baker D, Amor S. Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice Immunology. 140: 456-464. PMID 23876060 DOI: 10.1111/Imm.12155  0.074
2020 Meyer N, Bollache L, Galipaud M, Moreau J, Dechaume-Moncharmont FX, Afonso E, Angerbjörn A, Bêty J, Brown G, Ehrich D, Gilg V, Giroux MA, Hansen J, Lanctot R, Lang J, ... ... Smith P, et al. Behavioural responses of breeding arctic sandpipers to ground-surface temperature and primary productivity. The Science of the Total Environment. 755: 142485. PMID 33039934 DOI: 10.1016/j.scitotenv.2020.142485  0.073
2022 Silverstein A, Dudaev A, Studneva M, Aitken J, Blokh S, Miller AD, Tanasova S, Rose N, Ryals J, Borchers C, Nordstrom A, Moiseyakh M, Herrera AS, Skomorohov N, Marshall T, ... ... Smith PD, et al. Evolution of biomarker research in autoimmunity conditions for health professionals and clinical practice. Progress in Molecular Biology and Translational Science. 190: 219-276. PMID 36008000 DOI: 10.1016/bs.pmbts.2022.02.004  0.073
2018 Kas SM, de Ruiter J, Schut E, Bombardelli L, Wientjens E, Drenth AP, de Korte-Grimmerink R, Mahakena S, Phillips C, Smith PD, Klarenbeek S, van de Wetering K, Berns A, Wessels LFA, Jonkers J, et al. Transcriptomics and transposon mutagenesis identify multiple mechanisms of resistance to the FGFR inhibitor AZD4547. Cancer Research. PMID 30115694 DOI: 10.1158/0008-5472.CAN-18-0757  0.073
2016 Bulla M, Valcu M, Dokter AM, Dondua AG, Kosztolányi A, Rutten AL, Helm B, Sandercock BK, Casler B, Ens BJ, Spiegel CS, Hassell CJ, Küpper C, Minton C, Burgas D, ... ... Smith PA, et al. Unexpected diversity in socially synchronized rhythms of shorebirds. Nature. PMID 27880762 DOI: 10.1038/Nature20563  0.073
2007 Smith PM, Doherty M, Price MJ. The effect of crank rate strategy on peak aerobic power and peak physiological responses during arm crank ergometry Journal of Sports Sciences. 25: 711-718. PMID 17454538 DOI: 10.1080/02640410600831955  0.073
2020 Gleeson M, Counsell N, Cunningham D, Lawrie A, Clifton-Hadley L, Hawkes E, McMillan A, Ardeshna KM, Burton C, Chadwick N, Gambell J, Smith P, Mouncey P, Pocock C, Radford J, et al. Prognostic indices in diffuse large B-cell lymphoma in the rituximab era: an analysis of the UK National Cancer Research Institute R-CHOP 14 versus 21 phase 3 trial. British Journal of Haematology. PMID 32436212 DOI: 10.1111/bjh.16691  0.073
2005 Krausz E, Hughes JL, Smith PJ, Pace RJ, Arsköld SP. Assignment of the low-temperature fluorescence in oxygen-evolving photosystem II. Photosynthesis Research. 84: 193-9. PMID 16049774 DOI: 10.1007/s11120-004-7078-9  0.072
2015 Xu D, Chu KK, Diaz JA, Ashman M, Komiak JJ, Pleasant LM, Creamer C, Nichols K, Duh KHG, Smith PM, Chao PC, Dong L, Ye PD. 0.1-μm atomic layer deposition Al2O3 passivated InAlN/GaN high electron-mobility transistors for E-band power amplifiers Ieee Electron Device Letters. 36: 442-444. DOI: 10.1109/Led.2015.2409264  0.072
2011 Zipser MC, Eichhoff OM, Widmer DS, Schlegel NC, Schoenewolf NL, Stuart D, Liu W, Gardner H, Smith PD, Nuciforo P, Dummer R, Hoek KS. A proliferative melanoma cell phenotype is responsive to RAF/MEK inhibition independent of BRAF mutation status. Pigment Cell & Melanoma Research. 24: 326-33. PMID 21176117 DOI: 10.1111/j.1755-148X.2010.00823.x  0.072
2018 Auberson YP, Briard E, Rudolph B, Kaupmann K, Smith P, Oberhauser B. PET imaging of T cells: Target identification and feasibility assessment. Chemmedchem. PMID 29856125 DOI: 10.1002/cmdc.201800241  0.072
2012 Wang LK, Das U, Smith P, Shuman S. Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna (New York, N.Y.). 18: 2277-86. PMID 23118415 DOI: 10.1261/Rna.036061.112  0.072
2018 Decaudin D, El Botty R, Diallo B, Massonnet G, Fleury J, Naguez A, Raymondie C, Davies E, Smith A, Wilson J, Howes C, Smith PD, Cassoux N, Piperno-Neumann S, Roman-Roman S, et al. Selumetinib-based therapy in uveal melanoma patient-derived xenografts. Oncotarget. 9: 21674-21686. PMID 29774094 DOI: 10.18632/oncotarget.24670  0.072
2004 Deng L, Fairbank NJ, Fabry B, Smith PG, Maksym GN. Localized mechanical stress induces time-dependent actin cytoskeletal remodeling and stiffening in cultured airway smooth muscle cells. American Journal of Physiology. Cell Physiology. 287: C440-8. PMID 15070813 DOI: 10.1152/ajpcell.00374.2003  0.072
2015 Manjunatha UH, S Rao SP, Kondreddi RR, Noble CG, Camacho LR, Tan BH, Ng SH, Ng PS, Ma NL, Lakshminarayana SB, Herve M, Barnes SW, Yu W, Kuhen K, Blasco F, ... ... Smith PW, et al. Direct inhibitors of InhA are active against Mycobacterium tuberculosis. Science Translational Medicine. 7: 269ra3. PMID 25568071 DOI: 10.1126/Scitranslmed.3010597  0.072
2014 Bindon K, Kassara S, Hayasaka Y, Schulkin A, Smith P. Properties of wine polymeric pigments formed from anthocyanin and tannins differing in size distribution and subunit composition. Journal of Agricultural and Food Chemistry. 62: 11582-93. PMID 25356846 DOI: 10.1021/jf503922h  0.071
2012 Palomares M, Smith PR, Pitts CH. Enumeration of small and large numerosities: the effect of element visibility. Quarterly Journal of Experimental Psychology (2006). 65: 1185-94. PMID 22489791 DOI: 10.1080/17470218.2011.648647  0.071
2012 Takahashi O, Komaki R, Smith PD, Jürgensmeier JM, Ryan A, Bekele BN, Wistuba II, Jacoby JJ, Korshunova MV, Biernacka A, Erez B, Hosho K, Herbst RS, O'Reilly MS. Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 1641-54. PMID 22275507 DOI: 10.1158/1078-0432.CCR-11-2324  0.071
2008 Kakareka JW, Smith PD, Pohida TJ, Hendler RW. Simultaneous measurements of fast optical and proton current kinetics in the bacteriorhodopsin photocycle using an enhanced spectrophotometer. Journal of Biochemical and Biophysical Methods. 70: 1116-23. PMID 18160131 DOI: 10.1016/j.jprot.2007.11.004  0.071
2009 Liu P, Chary S, Devaraj R, Jing Y, Darlington CL, Smith PF, Tucker IG, Zhang H. Effects of aging on agmatine levels in memory-associated brain structures. Hippocampus. 18: 853-6. PMID 18481282 DOI: 10.1002/hipo.20448  0.071
2006 Smith P, Syed N, Crook T. Epigenetic inactivation implies a tumor suppressor function in hematologic malignancies for Polo-like kinase 2 but not Polo-like kinase 3. Cell Cycle (Georgetown, Tex.). 5: 1262-4. PMID 16868416 DOI: 10.4161/cc.5.12.2813  0.071
2011 Perriman DM, Scarvell JM, Waddington GS, Lueck CJ, Hughes AR, Neeman TM, Smith PN. Ultrasound assessment of the anatomical validity of T3 and L4 as sEMG recording sites. Journal of Biomechanics. 44: 1025-30. PMID 21376327 DOI: 10.1016/j.jbiomech.2011.02.007  0.071
2007 Fan DY, Hope AB, Smith PJ, Jia H, Pace RJ, Anderson JM, Chow WS. The stoichiometry of the two photosystems in higher plants revisited. Biochimica Et Biophysica Acta. 1767: 1064-72. PMID 17618597 DOI: 10.1016/j.bbabio.2007.06.001  0.07
2011 Zheng Y, Vagal S, McNamara E, Darlington CL, Smith PF. A dose-response analysis of the effects of L-baclofen on chronic tinnitus caused by acoustic trauma in rats. Neuropharmacology. 62: 940-6. PMID 22005094 DOI: 10.1016/j.neuropharm.2011.09.027  0.07
2017 Kondrat SA, Smith PJ, Carter JH, Hayward JS, Pudge GJ, Shaw G, Spencer MS, Bartley JK, Taylor SH, Hutchings GJ. The effect of sodium species on methanol synthesis and water-gas shift Cu/ZnO catalysts: utilising high purity zincian georgeite. Faraday Discussions. PMID 28197597 DOI: 10.1039/c6fd00202a  0.07
2017 Aitken P, Zheng Y, Smith PF. Ethovision™ analysis of open field behaviour in rats following bilateral vestibular loss. Journal of Vestibular Research : Equilibrium & Orientation. 27: 89-101. PMID 29064826 DOI: 10.3233/VES-170612  0.07
2010 Eve HE, Gambell J, Smith P, Qian W, Rule SA. The Simplified Mantle-Cell Lymphoma International Prognostic Index predicts overall survival but not progression-free survival in patients with mantle-cell lymphoma treated with fludarabine and cyclophosphamide +/- rituximab: results of a randomized phase II trial. Leukemia & Lymphoma. 50: 1709-11. PMID 19757310 DOI: 10.1080/10428190903186494  0.07
2010 Dawson LA, Smith PW. Therapeutic utility of NK3 receptor antagonists for the treatment of schizophrenia. Current Pharmaceutical Design. 16: 344-57. PMID 20109143 DOI: 10.2174/138161210790170067  0.07
2007 Smith PA, Selley DE, Sim-Selley LJ, Welch SP. Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors. European Journal of Pharmacology. 571: 129-37. PMID 17603035 DOI: 10.1016/J.Ejphar.2007.06.001  0.07
2018 Naleem N, Bentenitis N, Smith PE. A Kirkwood-Buff derived force field for alkaline earth halide salts. The Journal of Chemical Physics. 148: 222828. PMID 29907021 DOI: 10.1063/1.5019454  0.07
2008 Chaudhuri S, Smith PG. Cyclic strain-induced HSP27 phosphorylation modulates actin filaments in airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology. 39: 270-8. PMID 18390476 DOI: 10.1165/rcmb.2007-0263OC  0.07
2010 Goddard M, Smith PF, Ashton JC. Behavioural effects of co-administration of delta9-tetrahydrocannabinol with fluoxetine in rats. Pharmacology. 86: 125-8. PMID 20689343 DOI: 10.1159/000317059  0.069
2016 Nesbitt H, Byrne NM, Williams N, Ming L, Worthington J, Errington RJ, Patterson LH, Smith P, McKeown SR, McKenna DJ. Targeting hypoxic prostate tumours using the novel hypoxia-activated prodrug OCT1002 inhibits expression of genes associated with malignant progression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27697998 DOI: 10.1158/1078-0432.CCR-16-1361  0.069
2009 Smith PW, Wyman PA, Lovell P, Goodacre C, Serafinowska HT, Vong A, Harrington F, Flynn S, Bradley DM, Porter R, Coggon S, Murkitt G, Searle K, Thomas DR, Watson JM, et al. New quinoline NK3 receptor antagonists with CNS activity. Bioorganic & Medicinal Chemistry Letters. 19: 837-40. PMID 19117759 DOI: 10.1016/j.bmcl.2008.12.005  0.069
2009 Darlington CL, Goddard M, Zheng Y, Smith PF. Anxiety-related behavior and biogenic amine pathways in the rat following bilateral vestibular lesions. Annals of the New York Academy of Sciences. 1164: 134-9. PMID 19645891 DOI: 10.1111/j.1749-6632.2008.03725.x  0.069
2013 Yokokawa F, Wang G, Chan WL, Ang SH, Wong J, Ma I, Rao SP, Manjunatha U, Lakshminarayana SB, Herve M, Kounde C, Tan BH, Thayalan P, Ng SH, Nanjundappa M, ... ... Smith P, et al. Discovery of tetrahydropyrazolopyrimidine carboxamide derivatives as potent and orally active antitubercular agents. Acs Medicinal Chemistry Letters. 4: 451-5. PMID 24900693 DOI: 10.1021/Ml400071A  0.069
2020 Hitier M, Zhang YF, Sato G, Besnard S, Zheng Y, Smith PF. The effects of selective electrical stimulation of the rat cochlea on hippocampal field potentials. Hearing Research. 395: 108023. PMID 32702613 DOI: 10.1016/J.Heares.2020.108023  0.069
2006 Jin AJ, Prasad K, Smith PD, Lafer EM, Nossal R. Measuring the elasticity of clathrin-coated vesicles via atomic force microscopy. Biophysical Journal. 90: 3333-44. PMID 16473913 DOI: 10.1529/Biophysj.105.068742  0.069
2021 Teng B, Hayasaka Y, Smith PA, Bindon KA. Precipitation of Tannin-Anthocyanin Derivatives in Wine is Influenced by Acetaldehyde Concentration and Tannin Molecular Mass with Implications for the Development of Nonbleachable Pigments. Journal of Agricultural and Food Chemistry. PMID 33853320 DOI: 10.1021/acs.jafc.1c00396  0.069
2007 Hassan M, Riley J, Chernomordik V, Smith P, Pursley R, Lee SB, Capala J, Gandjbakhche AH. Fluorescence lifetime imaging system for in vivo studies. Molecular Imaging. 6: 229-36. PMID 17711778 DOI: 10.2310/7290.2007.00019  0.069
2004 Graham LN, Smith PA, Stoker JB, Mackintosh AF, Mary DA. Sympathetic neural hyperactivity and its normalization following unstable angina and acute myocardial infarction. Clinical Science (London, England : 1979). 106: 605-11. PMID 14759219 DOI: 10.1042/CS20030376  0.069
2006 Nussbaumer RJ, Caseri WR, Smith P. Reversible photochromic properties of TiO2-polymer nanocomposites. Journal of Nanoscience and Nanotechnology. 6: 459-63. PMID 16573045 DOI: 10.1166/jnn.2006.923  0.069
2015 Smith PD, Coulson-Thomas VJ, Foscarin S, Kwok JC, Fawcett JW. "GAG-ing with the neuron": The role of glycosaminoglycan patterning in the central nervous system. Experimental Neurology. PMID 26277685 DOI: 10.1016/J.Expneurol.2015.08.004  0.068
2003 Weiss M, Hettmer S, Smith P, Ladisch S. Inhibition of melanoma tumor growth by a novel inhibitor of glucosylceramide synthase. Cancer Research. 63: 3654-8. PMID 12839955  0.068
2010 Rimland J, Dunne A, Hunjan SS, Sasse R, Uings I, Montanari D, Caivano M, Shah P, Standing D, Gray D, Brown D, Cairns W, Trump R, Smith PW, Bertheleme N, et al. The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 20: 2340-3. PMID 20202837 DOI: 10.1016/J.Bmcl.2010.01.133  0.068
2021 McCoull W, Boyd S, Brown MR, Coen M, Collingwood O, Davies NL, Doherty A, Fairley G, Goldberg K, Hardaker E, He G, Hennessy EJ, Hopcroft P, Hodgson G, Jackson A, ... ... Smith PD, et al. Optimization of an Imidazo[1,2-]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with Efficacy. Journal of Medicinal Chemistry. PMID 34478292 DOI: 10.1021/acs.jmedchem.1c00920  0.068
2004 Zhang H, Smith P, Adler-Nissen J. Effects of degree of enzymatic interesterification on the physical properties of margarine fats: solid fat content, crystallization behavior, crystal morphology, and crystal network. Journal of Agricultural and Food Chemistry. 52: 4423-31. PMID 15237947 DOI: 10.1021/jf035022u  0.068
2005 Manjula BN, Tsai AG, Intaglietta M, Tsai CH, Ho C, Smith PK, Perumalsamy K, Kanika ND, Friedman JM, Acharya SA. Conjugation of multiple copies of polyethylene glycol to hemoglobin facilitated through thiolation: influence on hemoglobin structure and function. The Protein Journal. 24: 133-46. PMID 16096719 DOI: 10.1007/S10930-005-7837-2  0.068
2020 Kang W, Bindon KA, Wang X, Muhlack RA, Smith PA, Niimi J, Bastian SEP. Chemical and Sensory Impacts of Accentuated Cut Edges (ACE) Grape Must Polyphenol Extraction Technique on Shiraz Wines. Foods (Basel, Switzerland). 9. PMID 32751842 DOI: 10.3390/foods9081027  0.068
2012 Das U, Smith P, Shuman S. Structural insights to the metal specificity of an archaeal member of the LigD 3'-phosphoesterase DNA repair enzyme family. Nucleic Acids Research. 40: 828-36. PMID 21965539 DOI: 10.1093/Nar/Gkr767  0.068
2019 Kassara S, Li S, Smith P, Blando F, Bindon K. Pectolytic enzyme reduces the concentration of colloidal particles in wine due to changes in polysaccharide structure and aggregation properties. International Journal of Biological Macromolecules. PMID 31404601 DOI: 10.1016/j.ijbiomac.2019.08.043  0.068
2008 Smith PJ, Chin SF, Njoh K, Khan IA, Chappell MJ, Errington RJ. Cell cycle checkpoint-guarded routes to catenation-induced chromosomal instability. Seb Experimental Biology Series. 59: 219-42. PMID 18368926  0.068
2015 Caunt CJ, Sale MJ, Smith PD, Cook SJ. MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road. Nature Reviews. Cancer. 15: 577-92. PMID 26399658 DOI: 10.1038/nrc4000  0.068
2009 Shannon AM, Telfer BA, Smith PD, Babur M, Logie A, Wilkinson RW, Debray C, Stratford IJ, Williams KJ, Wedge SR. The mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) enhances the radiation responsiveness of lung and colorectal tumor xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6619-29. PMID 19843666 DOI: 10.1158/1078-0432.CCR-08-2958  0.068
2016 Talley DC, Delang L, Neyts J, Leyssen P, Smith PJ. Exploring the importance of zinc binding and steric/hydrophobic factors in novel HCV replication inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 26804234 DOI: 10.1016/j.bmcl.2016.01.035  0.068
2008 Smith PM, Chapman ML, Hazlehurst KE, Goss-Sampson MA. The influence of crank configuration on muscle activity and torque production during arm crank ergometry Journal of Electromyography and Kinesiology. 18: 598-605. PMID 17337211 DOI: 10.1016/j.jelekin.2006.12.006  0.068
2002 Sloane AJ, Duff JL, Wilson NL, Gandhi PS, Hill CJ, Hopwood FG, Smith PE, Thomas ML, Cole RA, Packer NH, Breen EJ, Cooley PW, Wallace DB, Williams KL, Gooley AA. High throughput peptide mass fingerprinting and protein macroarray analysis using chemical printing strategies. Molecular & Cellular Proteomics : McP. 1: 490-9. PMID 12239277 DOI: 10.1074/Mcp.M200020-Mcp200  0.068
2005 Gliddon CM, Darlington CL, Smith PF. Rapid vestibular compensation in guinea pig even with prolonged anesthesia. Neuroscience Letters. 371: 138-41. PMID 15519744 DOI: 10.1016/j.neulet.2004.08.056  0.067
2015 Bolton C, Smith P. Defining and Regulating Acute Inflammatory Lesion Formation during the Pathogenesis of Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis. Cns & Neurological Disorders Drug Targets. 14: 915-35. PMID 26177741 DOI: 10.2174/1871527314666150716103629  0.067
2012 Gunn BM, Morrison TE, Whitmore AC, Blevins LK, Hueston L, Fraser RJ, Herrero LJ, Ramirez R, Smith PN, Mahalingam S, Heise MT. Mannose binding lectin is required for alphavirus-induced arthritis/myositis. Plos Pathogens. 8: e1002586. PMID 22457620 DOI: 10.1371/Journal.Ppat.1002586  0.067
2014 Smith PW, Diagana TT, Yeung BKS. Progressing the global antimalarial portfolio: Finding drugs which target multiple Plasmodium life stages Parasitology. 141: 66-76. PMID 23746048 DOI: 10.1017/S0031182013000747  0.067
2017 Gawel R, Smith PA, Cicerale S, Keast R. The Mouthfeel of White Wine. Critical Reviews in Food Science and Nutrition. 0. PMID 28678530 DOI: 10.1080/10408398.2017.1346584  0.067
2003 Gliddon CM, Darlington CL, Smith PF. Activation of the hypothalamic-pituitary-adrenal axis following vestibular deafferentation in pigmented guinea pig. Brain Research. 964: 306-10. PMID 12576192 DOI: 10.1016/S0006-8993(02)04086-6  0.067
2009 Smith PF, Brandt T, Strupp M, Darlington CL, Zheng Y. Balance before reason in rats and humans. Annals of the New York Academy of Sciences. 1164: 127-33. PMID 19645890 DOI: 10.1111/j.1749-6632.2008.03726.x  0.067
2015 Boyles MS, Young L, Brown DM, MacCalman L, Cowie H, Moisala A, Smail F, Smith PJ, Proudfoot L, Windle AH, Stone V. Multi-walled carbon nanotube induced frustrated phagocytosis, cytotoxicity and pro-inflammatory conditions in macrophages are length dependent and greater than that of asbestos. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 1513-1528. PMID 26086123 DOI: 10.1016/j.tiv.2015.06.012  0.067
2014 Ward DN, Talley DC, Tavag M, Menji S, Schaughency P, Baier A, Smith PJ. UK-1 and structural analogs are potent inhibitors of hepatitis C virus replication. Bioorganic & Medicinal Chemistry Letters. 24: 609-12. PMID 24360997 DOI: 10.1016/j.bmcl.2013.12.012  0.067
2011 Smith P, Nair PA, Das U, Zhu H, Shuman S. Structures and activities of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily. Nucleic Acids Research. 39: 3310-20. PMID 21208981 DOI: 10.1093/Nar/Gkq1163  0.067
2007 Zhu H, Smith P, Wang LK, Shuman S. Structure-function analysis of the 3' phosphatase component of T4 polynucleotide kinase/phosphatase. Virology. 366: 126-36. PMID 17493655 DOI: 10.1016/J.Virol.2007.03.059  0.067
2015 Tanaka N, Takahashi S, Zhang Y, Krausz KW, Smith PB, Patterson AD, Gonzalez FJ. Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet. Biochimica Et Biophysica Acta. 1852: 1242-52. PMID 25736301 DOI: 10.1016/j.bbadis.2015.02.012  0.067
2010 Brown MR, Summers HD, Rees P, Chappell SC, Silvestre OF, Khan IA, Smith PJ, Errington RJ. Long-term time series analysis of quantum dot encoded cells by deconvolution of the autofluorescence signal. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 925-32. PMID 21290466 DOI: 10.1002/cyto.a.20936  0.067
2020 Covington M, He X, Scuron M, Li J, Collins R, Juvekar A, Shin N, Favata M, Gallagher K, Sarah S, Xue CB, Peel M, Burke K, Oliver J, Fay B, ... ... Smith P, et al. Preclinical characterization of itacitinib (INCB039110), a novel selective inhibitor of JAK1, for the treatment of inflammatory diseases. European Journal of Pharmacology. 173505. PMID 32861662 DOI: 10.1016/j.ejphar.2020.173505  0.067
2012 McRae JM, Dambergs RG, Kassara S, Parker M, Jeffery DW, Herderich MJ, Smith PA. Phenolic compositions of 50 and 30 year sequences of Australian red wines: the impact of wine age. Journal of Agricultural and Food Chemistry. 60: 10093-102. PMID 22967212 DOI: 10.1021/jf301571q  0.067
2013 Kondreddi RR, Jiricek J, Rao SP, Lakshminarayana SB, Camacho LR, Rao R, Herve M, Bifani P, Ma NL, Kuhen K, Goh A, Chatterjee AK, Dick T, Diagana TT, Manjunatha UH, ... Smith PW, et al. Design, synthesis, and biological evaluation of indole-2-carboxamides: a promising class of antituberculosis agents. Journal of Medicinal Chemistry. 56: 8849-59. PMID 24090347 DOI: 10.1021/Jm4012774  0.066
2015 McDonald JL, Cripps AW, Smith PK. Mediators, Receptors, and Signalling Pathways in the Anti-Inflammatory and Antihyperalgesic Effects of Acupuncture. Evidence-Based Complementary and Alternative Medicine : Ecam. 2015: 975632. PMID 26339274 DOI: 10.1155/2015/975632  0.066
2013 Wang LK, Smith P, Shuman S. Structure and mechanism of the 2',3' phosphatase component of the bacterial Pnkp-Hen1 RNA repair system. Nucleic Acids Research. 41: 5864-73. PMID 23595150 DOI: 10.1093/Nar/Gkt221  0.066
2009 Plassmeyer ML, Reiter K, Shimp RL, Kotova S, Smith PD, Hurt DE, House B, Zou X, Zhang Y, Hickman M, Uchime O, Herrera R, Nguyen V, Glen J, Lebowitz J, et al. Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate. The Journal of Biological Chemistry. 284: 26951-63. PMID 19633296 DOI: 10.1074/Jbc.M109.013706  0.066
2020 Cipcigan F, Smith P, Crain J, Hogner A, De Maria L, Llinas A, Ratkova E. Membrane Permeability in Cyclic Peptides is Modulated by Core Conformations. Journal of Chemical Information and Modeling. PMID 33350828 DOI: 10.1021/acs.jcim.0c00803  0.066
2022 Curthoys IS, Smith PF, de Miguel AR. Why Should Constant Stimulation of Saccular Afferents Modify the Posture and Gait of Patients with Bilateral Vestibular Dysfunction? The Saccular Substitution Hypothesis. Journal of Clinical Medicine. 11. PMID 35207405 DOI: 10.3390/jcm11041132  0.066
2006 Forootan SS, Foster CS, Aachi VR, Adamson J, Smith PH, Lin K, Ke Y. Prognostic significance of osteopontin expression in human prostate cancer. International Journal of Cancer. Journal International Du Cancer. 118: 2255-61. PMID 16331611 DOI: 10.1002/ijc.21619  0.066
2015 van Griensven J, De Weiggheleire A, Delamou A, Smith PG, Edwards T, Vandekerckhove P, Bah EI, Colebunders R, Herve I, Lazaygues C, Haba N, Lynen L. The Use of Ebola Convalescent Plasma to Treat Ebola Virus Disease in Resource-Constrained Settings: A Perspective From the Field. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 26261205 DOI: 10.1093/Cid/Civ680  0.066
2003 Horii A, Kitahara T, Smith PF, Darlington CL, Masumura C, Kubo T. Effects of unilateral labyrinthectomy on GAD, GAT1 and GABA receptor gene expression in the rat vestibular nucleus. Neuroreport. 14: 2359-2363. PMID 14663191 DOI: 10.1097/00001756-200312190-00014  0.066
2004 Ellmerich S, Takacs K, Mycko M, Waldner H, Wahid F, Boyton RJ, Smith PA, Amor S, Baker D, Hafler DA, Kuchroo VK, Altmann DM. Disease-related epitope spread in a humanized T cell receptor transgenic model of multiple sclerosis. European Journal of Immunology. 34: 1839-48. PMID 15214032 DOI: 10.1002/Eji.200324044  0.066
2021 Smith P, Lorenz CD. LiPyphilic: A Python Toolkit for the Analysis of Lipid Membrane Simulations. Journal of Chemical Theory and Computation. PMID 34450002 DOI: 10.1021/acs.jctc.1c00447  0.065
2020 Fisher L, Fisher A, Smith PN. Helicobacter pylori Related Diseases and Osteoporotic Fractures (Narrative Review). Journal of Clinical Medicine. 9. PMID 33053671 DOI: 10.3390/jcm9103253  0.065
2021 Huarte E, Peel MT, Verbist K, Fay BL, Bassett R, Albeituni S, Nichols KE, Smith PA. Ruxolitinib, a JAK1/2 Inhibitor, Ameliorates Cytokine Storm in Experimental Models of Hyperinflammation Syndrome. Frontiers in Pharmacology. 12: 650295. PMID 33981229 DOI: 10.3389/fphar.2021.650295  0.065
2002 Slud E, Stone M, Smith PJ, Goldstein M. Principal components representation of the two-dimensional coronal tongue surface. Phonetica. 59: 108-33. PMID 12232463 DOI: 10.1159/000066066  0.065
2004 Chen Y, Jia Z, Schaper A, Kristiansen M, Smith P, Wombacher R, Wendorff JH, Greiner A. Hydrolytic and enzymatic degradation of liquid-crystalline aromatic/aliphatic copolyesters. Biomacromolecules. 5: 11-6. PMID 14715002 DOI: 10.1021/bm034388c  0.065
2005 Wyman PA, Marshall HR, Flynn ST, King RJ, Thompson M, Smith PW, Hadley MS, Price GW, Scott CM, Dawson LA. Identification of a potent and selective 5-HT1B receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 15: 4708-12. PMID 16153839 DOI: 10.1016/j.bmcl.2005.07.085  0.065
2013 Boczonadi V, Smith PM, Pyle A, Gomez-Duran A, Schara U, Tulinius M, Chinnery PF, Horvath R. Altered 2-thiouridylation impairs mitochondrial translation in reversible infantile respiratory chain deficiency. Human Molecular Genetics. 22: 4602-15. PMID 23814040 DOI: 10.1093/hmg/ddt309  0.065
2005 Zhang R, Ashton J, Horii A, Darlington CL, Smith PF. Immunocytochemical and stereological analysis of GABA(B) receptor subunit expression in the rat vestibular nucleus following unilateral vestibular deafferentation. Brain Research. 1037: 107-13. PMID 15777758 DOI: 10.1016/j.brainres.2005.01.018  0.065
2006 Smith PD, McLean KJ, Murphy MA, Turnley AM, Cook MJ. Functional dentate gyrus neurogenesis in a rapid kindling seizure model. The European Journal of Neuroscience. 24: 3195-203. PMID 17156380 DOI: 10.1111/j.1460-9568.2006.05205.x  0.065
2018 Stiles L, Reynolds JN, Napper R, Zheng Y, Smith PF. Single neuron activity and c-Fos expression in the rat striatum following electrical stimulation of the peripheral vestibular system. Physiological Reports. 6: e13791. PMID 30003674 DOI: 10.14814/Phy2.13791  0.065
2013 Hendler RW, Meuse CW, Smith PD, Kakareka JW. Further studies with isolated absolute infrared spectra of bacteriorhodopsin photocycle intermediates: conformational changes and possible role of a new proton-binding center. Applied Spectroscopy. 67: 73-85. PMID 23317674 DOI: 10.1366/12-06662  0.064
2020 Yeleswaram S, Smith P, Burn T, Covington M, Juvekar A, Li Y, Squier P, Langmuir P. Inhibition of cytokine signaling by ruxolitinib and implications for COVID-19 treatment. Clinical Immunology (Orlando, Fla.). 108517. PMID 32585295 DOI: 10.1016/j.clim.2020.108517  0.064
2022 Gogleva A, Polychronopoulos D, Pfeifer M, Poroshin V, Ughetto M, Martin MJ, Thorpe H, Bornot A, Smith PD, Sidders B, Dry JR, Ahdesmäki M, McDermott U, Papa E, Bulusu KC. Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer. Nature Communications. 13: 1667. PMID 35351890 DOI: 10.1038/s41467-022-29292-7  0.064
2022 Gold B, Zhang J, Quezada LL, Roberts J, Ling Y, Wood M, Shinwari W, Goullieux L, Roubert C, Fraisse L, Bacqué E, Lagrange S, Filoche-Rommé B, Vieth M, Hipskind PA, ... ... Smith P, et al. Identification of β-Lactams Active against by a Consortium of Pharmaceutical Companies and Academic Institutions. Acs Infectious Diseases. PMID 35192346 DOI: 10.1021/acsinfecdis.1c00570  0.064
2005 Ashton JC, Friberg D, Darlington CL, Smith PF. Expression of the cannabinoid CB2 receptor in the rat cerebellum: an immunohistochemical study. Neuroscience Letters. 396: 113-6. PMID 16356641 DOI: 10.1016/j.neulet.2005.11.038  0.064
2015 Mhandire D, Lacerda M, Castel S, Mhandire K, Zhou D, Swart M, Shamu T, Smith P, Musingwini T, Wiesner L, Stray-Pedersen B, Dandara C. Effects of CYP2B6 and CYP1A2 Genetic Variation on Nevirapine Plasma Concentration and Pharmacodynamics as Measured by CD4 Cell Count in Zimbabwean HIV-Infected Patients. Omics : a Journal of Integrative Biology. 19: 553-62. PMID 26348712 DOI: 10.1089/omi.2015.0104  0.064
2012 Zheng Y, Cheung I, Smith PF. Performance in anxiety and spatial memory tests following bilateral vestibular loss in the rat and effects of anxiolytic and anxiogenic drugs Behavioural Brain Research. 235: 21-29. PMID 22824589 DOI: 10.1016/j.bbr.2012.07.025  0.064
2020 Langmuir P, Yeleswaram S, Smith P, Knorr B, Squier P. Design of Clinical Trials Evaluating Ruxolitinib, a JAK1/JAK2 Inhibitor, for Treatment of COVID-19-Associated Cytokine Storm. Delaware Journal of Public Health. 6: 50-54. PMID 34467111 DOI: 10.32481/djph.2020.07.015  0.064
2006 Smith PM, McCrindle E, Doherty M, Price MJ, Jones AM. Influence of crank rate on the slow component of pulmonary O(2) uptake during heavy arm-crank exercise. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. 31: 292-301. PMID 16770358 DOI: 10.1139/H05-039  0.064
2010 Nair PA, Smith P, Shuman S. Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily. Proceedings of the National Academy of Sciences of the United States of America. 107: 12822-7. PMID 20616014 DOI: 10.1073/Pnas.1005830107  0.064
2020 Walker RAJ, Colclough M, Limbert C, Smith PM. Perceived barriers to, and benefits of physical activity among British military veterans that are wounded, injured, and/or sick: a Behaviour Change Wheel perspective. Disability and Rehabilitation. 1-9. PMID 32568568 DOI: 10.1080/09638288.2020.1781940  0.063
2005 Hughes JL, Krausz E, Smith PJ, Pace RJ, Riesen H. Probing the lowest energy chlorophyll a states of photosystem II via selective spectroscopy: new insights on P680. Photosynthesis Research. 84: 93-8. PMID 16049760 DOI: 10.1007/s11120-004-7927-6  0.063
2015 Combrinck JM, Fong KY, Gibhard L, Smith PJ, Wright DW, Egan TJ. Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials. Malaria Journal. 14: 253. PMID 26099266 DOI: 10.1186/S12936-015-0729-9  0.063
2006 Szlosarek PW, Klabatsa A, Pallaska A, Sheaff M, Smith P, Crook T, Grimshaw MJ, Steele JP, Rudd RM, Balkwill FR, Fennell DA. In vivo loss of expression of argininosuccinate synthetase in malignant pleural mesothelioma is a biomarker for susceptibility to arginine depletion. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 7126-31. PMID 17145837 DOI: 10.1158/1078-0432.CCR-06-1101  0.063
2017 Smith PF. A Guerilla Guide to Common Problems in 'Neurostatistics': Essential Statistical Topics in Neuroscience. Journal of Undergraduate Neuroscience Education : June : a Publication of Fun, Faculty For Undergraduate Neuroscience. 16: R1-R12. PMID 29371855  0.063
2008 Sorich MJ, Smith PA, Miners JO, Mackenzie PI, McKinnon RA. Recent advances in the in silico modelling of UDP glucuronosyltransferase substrates Current Drug Metabolism. 9: 60-69. PMID 18220572 DOI: 10.2174/138920008783331167  0.063
2020 Smith PE, Enriquez-Hidalgo D, Hennessy D, McCabe MS, Kenny DA, Kelly AK, Waters SM. Sward type alters the relative abundance of members of the rumen microbial ecosystem in dairy cows. Scientific Reports. 10: 9317. PMID 32518306 DOI: 10.1038/s41598-020-66028-3  0.063
2009 Smith PJ, Khan IA, Errington RJ. Cytomics and cellular informatics--coping with asymmetry and heterogeneity in biological systems. Drug Discovery Today. 14: 271-7. PMID 19150508 DOI: 10.1016/j.drudis.2008.11.012  0.063
2004 Miners JO, Smith PA, Sorich MJ, McKinnon RA, Mackenzie PI. Predicting Human Drug Glucuronidation Parameters: Application of In Vitro and In Silico Modeling Approaches Annual Review of Pharmacology and Toxicology. 44: 1-25. PMID 14744236 DOI: 10.1146/annurev.pharmtox.44.101802.121546  0.063
2016 Aitken P, Benoit A, Zheng Y, Besnard S, Philoxene B, Le Gall A, Denise P, Smith PF. Hippocampal and striatal M1 -muscarinic acetylcholine receptors are down-regulated following bilateral vestibular loss in rats. Hippocampus. PMID 27569857 DOI: 10.1002/Hipo.22651  0.063
2013 White BJ, Smith PA, Dunn WR. Hydrogen sulphide-mediated vasodilatation involves the release of neurotransmitters from sensory nerves in pressurized mesenteric small arteries isolated from rats. British Journal of Pharmacology. 168: 785-93. PMID 22928888 DOI: 10.1111/j.1476-5381.2012.02187.x  0.063
2005 Acharya SA, Friedman JM, Manjula BN, Intaglietta M, Tsai AG, Winslow RM, Malavalli A, Vandegriff K, Smith PK. Enhanced molecular volume of conservatively pegylated Hb: (SP-PEG5K)6-HbA is non-hypertensive. Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 33: 239-55. PMID 16152690 DOI: 10.1081/Bio-200066365  0.063
2015 Pommier AJ, Farren M, Patel B, Wappett M, Michopoulos F, Smith NR, Kendrew J, Frith J, Huby R, Eberlein C, Campbell H, Womack C, Smith PD, Robertson J, Morgan S, et al. Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer. Cell Metabolism. PMID 26626460 DOI: 10.1016/j.cmet.2015.10.015  0.063
2009 Sheard PW, Smith PM, Paine TJ. Athlete compliance to therapist requested contraction intensity during proprioceptive neuromuscular facilitation. Manual Therapy. 14: 539-43. PMID 18996733 DOI: 10.1016/j.math.2008.08.006  0.063
2020 Pinto-Fernandez A, Salio M, Partridge T, Chen J, Vere G, Greenwood H, Olie CS, Damianou A, Scott HC, Pegg HJ, Chiarenza A, Díaz-Saez L, Smith P, Gonzalez-Lopez C, Patel B, et al. Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity. British Journal of Cancer. PMID 33214684 DOI: 10.1038/s41416-020-01167-y  0.063
2015 Sewell F, Ragan I, Marczylo T, Anderson B, Braun A, Casey W, Dennison N, Griffiths D, Guest R, Holmes T, van Huygevoort T, Indans I, Kenny T, Kojima H, Lee K, ... ... Smith P, et al. A global initiative to refine acute inhalation studies through the use of 'evident toxicity' as an endpoint: towards adoption of the Fixed Concentration Procedure. Regulatory Toxicology and Pharmacology : Rtp. PMID 26505531 DOI: 10.1016/j.yrtph.2015.10.018  0.063
2015 Ng PS, Manjunatha UH, Rao SP, Camacho LR, Ma NL, Herve M, Noble CG, Goh A, Peukert S, Diagana TT, Smith PW, Kondreddi RR. Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents. European Journal of Medicinal Chemistry. 106: 144-156. PMID 26544629 DOI: 10.1016/j.ejmech.2015.10.008  0.063
2005 Ashton JC, Appleton I, Darlington CL, Smith PF. Immunohistochemical localization of cerebrovascular cannabinoid CB1 receptor protein. Journal of Cardiovascular Pharmacology. 44: 517-9. PMID 15505486 DOI: 10.1097/00005344-200411000-00001  0.063
2006 Smith FL, Javed RR, Smith PA, Dewey WL, Gabra BH. PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 54: 474-80. PMID 17056270 DOI: 10.1016/j.phrs.2006.09.007  0.063
2011 Price MJ, Bottoms L, Smith PM, Nicholettos A. The effects of an increasing versus constant crank rate on peak physiological responses during incremental arm crank ergometry Journal of Sports Sciences. 29: 263-269. PMID 21154011 DOI: 10.1080/02640414.2010.525520  0.063
2019 Anderson AM, Friis C, Gratto-Trevor CL, Morrison RIG, Smith PA, Nol E. Consistent declines in wing lengths of Calidridine sandpipers suggest a rapid morphometric response to environmental change. Plos One. 14: e0213930. PMID 30943247 DOI: 10.1371/journal.pone.0213930  0.063
2018 Phillips EH, Lannon MM, Lopes A, Chadwick H, Jones G, Sieniawski M, Davies A, Wood K, Clifton-Hadley L, Smith P, Lawrie A, Chadwick N, Lennard AL. High-dose chemotherapy and autologous stem cell transplantation in enteropathy-associated and other aggressive T-cell lymphomas: a UK NCRI/Cancer Research UK Phase II Study. Bone Marrow Transplantation. PMID 30104718 DOI: 10.1038/s41409-018-0294-2  0.063
2002 Karpowich NK, Huang HH, Smith PC, Hunt JF. Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding. The Journal of Biological Chemistry. 278: 8429-34. PMID 12468528 DOI: 10.1074/JBC.M212239200  0.063
2022 Rice CM, Sarkar P, Walsh P, Owen D, Bidgood C, Smith P, Kane NM, Asghar S, Marks DI, Scolding NJ. Repeat infusion of autologous bone marrow cells in progressive multiple sclerosis - A phase I extension study (SIAMMS II). Multiple Sclerosis and Related Disorders. 61: 103782. PMID 35397289 DOI: 10.1016/j.msard.2022.103782  0.062
2013 Marangon M, Stockdale VJ, Munro P, Trethewey T, Schulkin A, Holt HE, Smith PA. Addition of carrageenan at different stages of winemaking for white wine protein stabilization. Journal of Agricultural and Food Chemistry. 61: 6516-24. PMID 23756713 DOI: 10.1021/jf401712d  0.062
2009 Holton MD, Silvestre OR, Errington RJ, Smith PJ, Matthews DR, Rees P, Summers HD. Stroboscopic fluorescence lifetime imaging. Optics Express. 17: 5205-16. PMID 19333284  0.062
2017 He J, Zhu Y, Aa J, Smith PF, De Ridder D, Wang G, Zheng Y. Brain Metabolic Changes in Rats following Acoustic Trauma. Frontiers in Neuroscience. 11: 148. PMID 28392756 DOI: 10.3389/fnins.2017.00148  0.062
2022 Tu E, McGlinchey K, Wang J, Martin P, Ching SL, Floc'h N, Kurasawa J, Starrett JH, Lazdun Y, Wetzel L, Nuttall B, Ng FS, Coffman KT, Smith PD, Politi K, et al. Anti-PD-L1 and anti-CD73 combination therapy promotes T cell response to EGFR-mutated NSCLC. Jci Insight. 7. PMID 35132961 DOI: 10.1172/jci.insight.142843  0.062
2014 Hingorani K, Pace R, Whitney S, Murray JW, Smith P, Cheah MH, Wydrzynski T, Hillier W. Photo-oxidation of tyrosine in a bio-engineered bacterioferritin 'reaction centre'-a protein model for artificial photosynthesis. Biochimica Et Biophysica Acta. 1837: 1821-34. PMID 25107631 DOI: 10.1016/j.bbabio.2014.07.019  0.062
2010 Zheng Y, Vagal S, Zhu XX, de Waele C, Smith PF, Wang G, Zhang M, Darlington CL. The effects of the Chinese herbal medicine EMF01 on salicylate-induced tinnitus in rats. Journal of Ethnopharmacology. 128: 545-8. PMID 20138209 DOI: 10.1016/j.jep.2010.01.053  0.062
2014 Bindon KA, Madani SH, Pendleton P, Smith PA, Kennedy JA. Factors affecting skin tannin extractability in ripening grapes. Journal of Agricultural and Food Chemistry. 62: 1130-41. PMID 24432763 DOI: 10.1021/jf4050606  0.062
2005 Smith PA, Morris-Downes M, Heijmans N, Pryce G, Arter E, O'Neill JK, Hart B', Baker D, Amor S. Epitope spread is not critical for the relapse and progression of MOG 8-21 induced EAE in Biozzi ABH mice. Journal of Neuroimmunology. 164: 76-84. PMID 15927270 DOI: 10.1016/J.Jneuroim.2005.04.006  0.062
2013 Lim SP, Wang QY, Noble CG, Chen YL, Dong H, Zou B, Yokokawa F, Nilar S, Smith P, Beer D, Lescar J, Shi PY. Ten years of dengue drug discovery: progress and prospects. Antiviral Research. 100: 500-19. PMID 24076358 DOI: 10.1016/j.antiviral.2013.09.013  0.062
2013 Hamerton I, McNamara LT, Howlin BJ, Smith PA, Cross P, Ward S. Examining the Initiation of the Polymerization Mechanism and Network Development in Aromatic Polybenzoxazines. Macromolecules. 46: 5117-5132. PMID 23853391 DOI: 10.1021/ma401014h  0.062
2008 Smith PW, Dawson LA. Neurokinin 3 (NK3) receptor modulators for the treatment of psychiatric disorders. Recent Patents On Cns Drug Discovery. 3: 1-15. PMID 18221236 DOI: 10.2174/157488908783421447  0.062
2021 Smith P. Animal Models of Multiple Sclerosis. Current Protocols. 1: e185. PMID 34170637 DOI: 10.1002/cpz1.185  0.062
2004 Sorich MJ, Miners JO, McKinnon RA, Smith PA. Multiple Pharmacophores for the Investigation of Human UDP-Glucuronosyltransferase Isoform Substrate Selectivity Molecular Pharmacology. 65: 301-308. PMID 14742671 DOI: 10.1124/mol.65.2.301  0.062
2018 Howell MD, Fitzsimons C, Smith P. JAK/STAT inhibitors and other small molecule cytokine antagonists for the treatment of allergic disease. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. PMID 29454096 DOI: 10.1016/j.anai.2018.02.012  0.062
2007 Nair PA, Nandakumar J, Smith P, Odell M, Lima CD, Shuman S. Structural basis for nick recognition by a minimal pluripotent DNA ligase. Nature Structural & Molecular Biology. 14: 770-8. PMID 17618295 DOI: 10.1038/Nsmb1266  0.061
2007 Smith PF. Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. Expert Review of Neurotherapeutics. 7: 1157-63. PMID 17868014 DOI: 10.1586/14737175.7.9.1157  0.061
2011 Chakravarty AK, Smith P, Shuman S. Structures of RNA 3'-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis. Proceedings of the National Academy of Sciences of the United States of America. 108: 21034-9. PMID 22167800 DOI: 10.1073/Pnas.1115560108  0.061
2020 Jackson AC, Pinter TBJ, Talley DC, Baker-Agha A, Patel D, Smith PJ, Franz KJ. Benzimidazole and Benzoxazole Zinc Chelators as Inhibitors of Metallo-β-Lactamase NDM-1. Chemmedchem. PMID 33211374 DOI: 10.1002/cmdc.202000607  0.061
2014 Jacewicz A, Schwer B, Smith P, Shuman S. Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28. Nucleic Acids Research. 42: 12885-98. PMID 25303995 DOI: 10.1093/Nar/Gku930  0.061
2003 McGregor A, Smith PM, Ross GF, Taylor RW, Turnbull DM, Lightowlers RN. Bridging PNAs can bind preferentially to a deleted mitochondrial DNA template but replication by mitochondrial DNA polymerase gamma in vitro is not impaired. Biochimica Et Biophysica Acta. 1629: 73-83. PMID 14522082 DOI: 10.1016/J.Bbaexp.2003.08.005  0.061
2012 Marangon M, Van Sluyter SC, Robinson EM, Muhlack RA, Holt HE, Haynes PA, Godden PW, Smith PA, Waters EJ. Degradation of white wine haze proteins by Aspergillopepsin I and II during juice flash pasteurization. Food Chemistry. 135: 1157-65. PMID 22953838 DOI: 10.1016/J.Foodchem.2012.05.042  0.061
2020 Scuron MD, Fay BL, Connell AJ, Peel MT, Smith PA. Ruxolitinib Cream Has Dual Efficacy on Pruritus and Inflammation in Experimental Dermatitis. Frontiers in Immunology. 11: 620098. PMID 33658996 DOI: 10.3389/fimmu.2020.620098  0.061
2021 Vaclova T, Grazini U, Ward L, O'Neill D, Markovets A, Huang X, Chmielecki J, Hartmaier R, Thress KS, Smith PD, Barrett JC, Downward J, de Bruin EC. Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers. Nature Communications. 12: 1780. PMID 33741979 DOI: 10.1038/s41467-021-22057-8  0.061
2010 Kemp JP, Smith PM, Pyle A, Neeve VC, Tuppen HA, Schara U, Talim B, Topaloglu H, Holinski-Feder E, Abicht A, Czermin B, Lochmüller H, McFarland R, Chinnery PF, Chrzanowska-Lightowlers ZM, et al. Nuclear factors involved in mitochondrial translation cause a subgroup of combined respiratory chain deficiency. Brain : a Journal of Neurology. 134: 183-95. PMID 21169334 DOI: 10.1093/brain/awq320  0.061
2004 Silverman EJ, Maeda A, Wei J, Smith P, Beggs JD, Lin RJ. Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Molecular and Cellular Biology. 24: 10101-10. PMID 15542821 DOI: 10.1128/Mcb.24.23.10101-10110.2004  0.061
2015 Stiles L, Smith PF. The vestibular-basal ganglia connection: balancing motor control. Brain Research. 1597: 180-8. PMID 25498858 DOI: 10.1016/j.brainres.2014.11.063  0.061
2014 Smith P, Endris R, Kronvall G, Thomas V, Verner-Jeffreys D, Wilhelm C, Dalsgaard I. Epidemiological cut-off values for Flavobacterium psychrophilum MIC data generated by a standard test protocol. Journal of Fish Diseases. PMID 25546427 DOI: 10.1111/jfd.12336  0.061
2016 Rooney C, Geh C, Williams V, Heuckmann JM, Menon R, Schneider P, Al-Kadhimi K, Dymond M, Smith NR, Baker D, French T, Smith PD, Harrington EA, Barrett JC, Kilgour E. Characterization of FGFR1 Locus in sqNSCLC Reveals a Broad and Heterogeneous Amplicon. Plos One. 11: e0149628. PMID 26905262 DOI: 10.1371/journal.pone.0149628  0.061
2003 Adam PJ, Berry J, Loader JA, Tyson KL, Craggs G, Smith P, De Belin J, Steers G, Pezzella F, Sachsenmeir KF, Stamps AC, Herath A, Sim E, O'Hare MJ, Harris AL, et al. Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro. Molecular Cancer Research : McR. 1: 826-35. PMID 14517345  0.061
2019 Sale MJ, Minihane E, Monks NR, Gilley R, Richards FM, Schifferli KP, Andersen CL, Davies EJ, Vicente MA, Ozono E, Markovets A, Dry JR, Drew L, Flemington V, Proia T, ... ... Smith PD, et al. Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors. Nature Communications. 10: 5167. PMID 31727888 DOI: 10.1038/s41467-019-12409-w  0.061
2007 Forootan SS, Wong YC, Dodson A, Wang X, Lin K, Smith PH, Foster CS, Ke Y. Increased Id-1 expression is significantly associated with poor survival of patients with prostate cancer. Human Pathology. 38: 1321-9. PMID 17599389 DOI: 10.1016/j.humpath.2007.02.011  0.061
2003 Smith PF. Cannabinoids in the treatment of pain and spasticity in multiple sclerosis. Current Opinion in Investigational Drugs (London, England : 2000). 3: 859-64. PMID 12137404  0.061
2016 Kingston MJ, Perriman DM, Neeman T, Smith PN, Webb AL. Contrast agent comparison for three-dimensional micro-CT angiography: A cadaveric study. Contrast Media & Molecular Imaging. PMID 27075920 DOI: 10.1002/cmmi.1695  0.061
2006 Gong C, Smith P, Shuman S. Structure-function analysis of Plasmodium RNA triphosphatase and description of a triphosphate tunnel metalloenzyme superfamily that includes Cet1-like RNA triphosphatases and CYTH proteins. Rna (New York, N.Y.). 12: 1468-74. PMID 16809816 DOI: 10.1261/Rna.119806  0.06
2002 Sorich MJ, Smith PA, McKinnon RA, Miners JO. Pharmacophore and quantitative structure activity relationship modelling of UDP-glucuronosyltransferase 1A1 (UGT1A1) substrates Pharmacogenetics. 12: 635-645. PMID 12439224 DOI: 10.1097/00008571-200211000-00008  0.06
2016 Edwards T, Semple MG, De Weggheleire A, Claeys Y, De Crop M, Menten J, Ravinetto R, Temmerman S, Lynen L, Bah EI, Smith PG, van Griensven J. Design and analysis considerations in the Ebola_Tx trial evaluating convalescent plasma in the treatment of Ebola virus disease in Guinea during the 2014-2015 outbreak. Clinical Trials (London, England). PMID 26768570 DOI: 10.1177/1740774515621056  0.06
2019 Ehrich D, Schmidt NM, Gauthier G, Alisauskas R, Angerbjörn A, Clark K, Ecke F, Eide NE, Framstad E, Frandsen J, Franke A, Gilg O, Giroux MA, Henttonen H, Hörnfeldt B, ... ... Smith PA, et al. Documenting lemming population change in the Arctic: Can we detect trends? Ambio. PMID 31332767 DOI: 10.1007/S13280-019-01198-7  0.06
2012 Zheng Y, Balabhadrapatruni S, Masumura C, Darlington CL, Smith PF. Effects of the putative cognitive-enhancing ampakine, CX717, on attention and object recognition memory. Current Alzheimer Research. 8: 876-82. PMID 22171951 DOI: 10.2174/156720511798192709  0.06
2015 Bailly A, Perrin A, Bou Malhab LJ, Pion E, Larance M, Nagala M, Smith P, O'Donohue MF, Gleizes PE, Zomerdijk J, Lamond AI, Xirodimas DP. The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway. Oncogene. PMID 25867069 DOI: 10.1038/onc.2015.104  0.06
2006 Bernstein DM, Rogers R, Smith P, Chevalier J. The toxicological response of Brazilian chrysotile asbestos: a multidose subchronic 90-day inhalation toxicology study with 92-day recovery to assess cellular and pathological response. Inhalation Toxicology. 18: 313-32. PMID 16513591 DOI: 10.1080/08958370500515871  0.06
2010 Johnson DJ, Forbes IT, Watson SP, Garzya V, Stevenson GI, Walker GR, Mudhar HS, Flynn ST, Wyman PA, Smith PW, Murkitt GS, Lucas AJ, Mookherjee CR, Watson JM, Gartlon JE, et al. The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M1 agonists. Bioorganic & Medicinal Chemistry Letters. 20: 5434-8. PMID 20709550 DOI: 10.1016/j.bmcl.2010.07.097  0.06
2002 Horii A, Smith PF, Darlington CL. Application of real-time quantitative polymerase chain reaction to quantification of glutamate receptor gene expression in the vestibular brainstem and cerebellum. Brain Research. Brain Research Protocols. 9: 77-83. PMID 11852273 DOI: 10.1016/S1385-299X(01)00139-8  0.06
2002 Gasco M, Bell AK, Heath V, Sullivan A, Smith P, Hiller L, Yulug I, Numico G, Merlano M, Farrell PJ, Tavassoli M, Gusterson B, Crook T. Epigenetic inactivation of 14-3-3 sigma in oral carcinoma: association with p16(INK4a) silencing and human papillomavirus negativity. Cancer Research. 62: 2072-6. PMID 11929827  0.06
2011 Burgess SE, MacLaughlin EJ, Smith PA, Salcido A, Benton TJ. Blood pressure rising: differences between current clinical and recommended measurement techniques. Journal of the American Society of Hypertension : Jash. 5: 484-8. PMID 22015319 DOI: 10.1016/j.jash.2011.08.007  0.06
2015 Chukwujekwu JC, Rengasamy KR, de Kock CA, Smith PJ, Slavětínská LP, van Staden J. Alpha-glucosidase inhibitory and antiplasmodial properties of terpenoids from the leaves of Buddleja saligna Willd. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-4. PMID 25694064 DOI: 10.3109/14756366.2014.1003927  0.06
2010 Ward SE, Harries M, Aldegheri L, Andreotti D, Ballantine S, Bax BD, Harris AJ, Harker AJ, Lund J, Melarange R, Mingardi A, Mookherjee C, Mosley J, Neve M, Oliosi B, ... ... Smith PW, et al. Discovery of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a novel clinical AMPA receptor positive modulator. Journal of Medicinal Chemistry. 53: 5801-12. PMID 20614889 DOI: 10.1021/jm1005429  0.06
2004 Smith PF. Medicinal cannabis extracts for the treatment of multiple sclerosis. Current Opinion in Investigational Drugs (London, England : 2000). 5: 727-30. PMID 15298068  0.06
2012 Dambergs RG, Mercurio MD, Kassara S, Cozzolino D, Smith PA. Rapid measurement of methyl cellulose precipitable tannins using ultraviolet spectroscopy with chemometrics: application to red wine and inter-laboratory calibration transfer. Applied Spectroscopy. 66: 656-64. PMID 22732536 DOI: 10.1366/11-06516  0.06
2010 Tanaka N, Smith P, Shuman S. Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer. Structure (London, England : 1993). 18: 449-57. PMID 20399182 DOI: 10.1016/J.Str.2010.01.016  0.06
2011 Hendler RW, Meuse CW, Braiman MS, Smith PD, Kakareka JW. Infrared and visible absolute and difference spectra of bacteriorhodopsin photocycle intermediates. Applied Spectroscopy. 65: 1029-45. PMID 21929858 DOI: 10.1366/11-06302  0.06
2015 Tolcher AW, Khan K, Ong M, Banerji U, Papadimitrakopoulou V, Gandara DR, Patnaik A, Baird RD, Olmos D, Garrett CR, Skolnik JM, Rubin EH, Smith PD, Huang P, Learoyd M, et al. Antitumor activity in RAS-driven tumors by blocking AKT and MEK. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 739-48. PMID 25516890 DOI: 10.1158/1078-0432.CCR-14-1901  0.059
2015 Deibert BJ, Zhang J, Smith PF, Chapman KW, Rangan S, Banerjee D, Tan K, Wang H, Pasquale N, Chen F, Lee KB, Dismukes GC, Chabal YJ, Li J. Surface and Structural Investigation of a MnOx Birnessite-Type Water Oxidation Catalyst Formed under Photocatalytic Conditions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26263021 DOI: 10.1002/Chem.201501930  0.059
2015 Chirehwa MT, Rustomjee R, Mthiyane T, Onyebujoh P, Smith P, McIlleron H, Denti P. Model-based evaluation of higher doses of rifampicin using a semi-mechanistic model incorporating auto-induction and saturation of hepatic extraction. Antimicrobial Agents and Chemotherapy. PMID 26552972 DOI: 10.1128/Aac.01830-15  0.059
2014 Harari D, Abramovich R, Zozulya A, Smith P, Pouly S, Köster M, Hauser H, Schreiber G. Bridging the species divide: Transgenic mice humanized for type-I interferon response Plos One. 9. PMID 24416207 DOI: 10.1371/journal.pone.0084259  0.059
2010 Yao S, Bee A, Brewer D, Dodson A, Beesley C, Ke Y, Ambroisine L, Fisher G, Møller H, Dickinson T, Gerard P, Lian LY, Risk J, Lane B, Smith P, et al. PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention. Genes & Cancer. 1: 444-64. PMID 21779455 DOI: 10.1177/1947601910376079  0.059
1982 Smith PA, Sunter JP, Case RM. Progressive atrophy of pancreatic acinar tissue in rats fed a copper-deficient diet supplemented with D-penicillamine or triethylene tetramine: morphological and physiological studies. Digestion. 23: 16-30. PMID 7084566 DOI: 10.1159/000198706  0.059
2019 Howell MD, Kuo FI, Smith PA. Targeting the Janus Kinase Family in Autoimmune Skin Diseases. Frontiers in Immunology. 10: 2342. PMID 31649667 DOI: 10.3389/fimmu.2019.02342  0.059
2002 Maclennan KM, Darlington CL, Smith PF. The CNS effects of Ginkgo biloba extracts and ginkgolide B. Progress in Neurobiology. 67: 235-57. PMID 12169298 DOI: 10.1016/S0301-0082(02)00015-1  0.059
2016 Griesdoorn V, Brown MR, Wiltshire M, Smith PJ, Errington RJ. Tracking the Cyclin B1-GFP Sensor to Profile the Pattern of Mitosis Versus Mitotic Bypass. Methods in Molecular Biology (Clifton, N.J.). 1342: 279-85. PMID 26254931 DOI: 10.1007/978-1-4939-2957-3_17  0.059
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