P P A Humphrey - Publications


41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Michel AD, Thompson KM, Simon J, Boyfield I, Fonfria E, Humphrey PP. Species and response dependent differences in the effects of MAPK inhibitors on P2X(7) receptor function. British Journal of Pharmacology. 149: 948-57. PMID 17031382 DOI: 10.1038/sj.bjp.0706938  0.326
2006 Michel AD, Xing M, Thompson KM, Jones CA, Humphrey PP. Decavanadate, a P2X receptor antagonist, and its use to study ligand interactions with P2X7 receptors. European Journal of Pharmacology. 534: 19-29. PMID 16487507 DOI: 10.1016/j.ejphar.2006.01.009  0.38
2004 Beattie DT, Smith JA, Marquess D, Vickery RG, Armstrong SR, Pulido-Rios T, McCullough JL, Sandlund C, Richardson C, Mai N, Humphrey PP. The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo. British Journal of Pharmacology. 143: 549-60. PMID 15466450 DOI: 10.1038/sj.bjp.0705929  0.354
2004 Jones CA, Vial C, Sellers LA, Humphrey PP, Evans RJ, Chessell IP. Functional regulation of P2X6 receptors by N-linked glycosylation: identification of a novel alpha beta-methylene ATP-sensitive phenotype. Molecular Pharmacology. 65: 979-85. PMID 15044628 DOI: 10.1124/Mol.65.4.979  0.38
2001 Cole SL, Schindler M, Sellers LA, Humphrey PP. Titrating the expression of a Gi protein-coupled receptor using an ecdysone-inducible system in CHO-K1 cells. Receptors & Channels. 7: 289-302. PMID 11697234  0.38
2001 Hibell AD, Thompson KM, Simon J, Xing M, Humphrey PP, Michel AD. Species- and agonist-dependent differences in the deactivation-kinetics of P2X7 receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 363: 639-48. PMID 11414659  0.316
2001 Carruthers AM, Sellers LA, Jenkins DW, Jarvie EM, Feniuk W, Humphrey PP. Adenosine A(1) receptor-mediated inhibition of protein kinase A-induced calcitonin gene-related peptide release from rat trigeminal neurons. Molecular Pharmacology. 59: 1533-41. PMID 11353815  0.332
2001 Alderton F, Humphrey PP, Sellers LA. High-intensity p38 kinase activity is critical for p21(cip1) induction and the antiproliferative function of G(i) protein-coupled receptors. Molecular Pharmacology. 59: 1119-28. PMID 11306695  0.343
2001 Smith PA, Sellers LA, Humphrey PP. Somatostatin activates two types of inwardly rectifying K+ channels in MIN-6 cells. The Journal of Physiology. 532: 127-42. PMID 11283230  0.344
2001 Hibell AD, Thompson KM, Xing M, Humphrey PP, Michel AD. Complexities of measuring antagonist potency at P2X(7) receptor orthologs. The Journal of Pharmacology and Experimental Therapeutics. 296: 947-57. PMID 11181928  0.312
2001 Khakh BS, Burnstock G, Kennedy C, King BF, North RA, Séguéla P, Voigt M, Humphrey PP. International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacological Reviews. 53: 107-18. PMID 11171941  0.396
2001 Simon J, Vigne P, Eklund KM, Michel AD, Carruthers AM, Humphrey PP, Frelin C, Barnard EA. Activity of adenosine diphosphates and triphosphates on a P2Y(T) -type receptor in brain capillary endothelial cells. British Journal of Pharmacology. 132: 173-82. PMID 11156575 DOI: 10.1038/sj.bjp.0703816  0.39
2000 Selmer IS, Schindler M, Humphrey PP, Waldvogel HJ, Faull RL, Emson PC. First localisation of somatostatin sst(4) receptor protein in selected human brain areas: an immunohistochemical study. Brain Research. Molecular Brain Research. 82: 114-25. PMID 11042364 DOI: 10.1016/S0169-328X(00)00186-8  0.345
2000 Sellers LA, Alderton F, Carruthers AM, Schindler M, Humphrey PP. Receptor isoforms mediate opposing proliferative effects through gbetagamma-activated p38 or Akt pathways. Molecular and Cellular Biology. 20: 5974-85. PMID 10913180  0.337
2000 Selmer IS, Schindler M, Humphrey PP, Emson PC. Immunohistochemical localization of the somatostatin sst(4) receptor in rat brain. Neuroscience. 98: 523-33. PMID 10869846 DOI: 10.1016/S0306-4522(00)00147-0  0.348
2000 Selmer I, Schindler M, Allen JP, Humphrey PP, Emson PC. Advances in understanding neuronal somatostatin receptors. Regulatory Peptides. 90: 1-18. PMID 10828487 DOI: 10.1016/S0167-0115(00)00108-7  0.344
2000 Michel AD, Kaur R, Chessell IP, Humphrey PP. Antagonist effects on human P2X(7) receptor-mediated cellular accumulation of YO-PRO-1. British Journal of Pharmacology. 130: 513-20. PMID 10821778 DOI: 10.1038/sj.bjp.0703368  0.359
2000 Feniuk W, Jarvie E, Luo J, Humphrey PP. Selective somatostatin sst(2) receptor blockade with the novel cyclic octapeptide, CYN-154806. Neuropharmacology. 39: 1443-50. PMID 10818260  0.363
2000 Jones CA, Chessell IP, Simon J, Barnard EA, Miller KJ, Michel AD, Humphrey PP. Functional characterization of the P2X(4) receptor orthologues. British Journal of Pharmacology. 129: 388-94. PMID 10694247 DOI: 10.1038/sj.bjp.0703059  0.364
1999 Hathway GJ, Humphrey PP, Kendrick KM. Evidence that somatostatin sst2 receptors mediate striatal dopamine release. British Journal of Pharmacology. 128: 1346-52. PMID 10578151 DOI: 10.1038/Sj.Bjp.0702934  0.306
1999 Schindler M, Humphrey PP, Löhrke S, Friauf E. Immunohistochemical localization of the somatostatin sst2(b) receptor splice variant in the rat central nervous system. Neuroscience. 90: 859-74. PMID 10218786 DOI: 10.1016/S0306-4522(98)00483-7  0.358
1999 Carruthers AM, Warner AJ, Michel AD, Feniuk W, Humphrey PP. Activation of adenylate cyclase by human recombinant sst5 receptors expressed in CHO-K1 cells and involvement of Galphas proteins. British Journal of Pharmacology. 126: 1221-9. PMID 10205012 DOI: 10.1038/sj.bjp.0702401  0.32
1999 Michel AD, Chessell IP, Humphrey PP. Ionic effects on human recombinant P2X7 receptor function. Naunyn-Schmiedeberg's Archives of Pharmacology. 359: 102-9. PMID 10048594  0.311
1998 Alderton F, Fan TP, Schindler M, Humphrey PP. Rat somatostatin sst2(a) and sst2(b) receptor isoforms mediate opposite effects on cell proliferation. British Journal of Pharmacology. 125: 1630-3. PMID 9886753 DOI: 10.1038/sj.bjp.0702282  0.313
1998 Miller KJ, Michel AD, Chessell IP, Humphrey PP. Cibacron blue allosterically modulates the rat P2X4 receptor. Neuropharmacology. 37: 1579-86. PMID 9886680  0.366
1998 Humphrey PP. The characterization and classification of receptors. Journal of Receptor and Signal Transduction Research. 18: 345-62. PMID 9879065 DOI: 10.3109/10799899809047751  0.347
1998 Kirkup AJ, Eastwood C, Grundy D, Chessell IP, Humphrey PP. Characterization of adenosine receptors evoking excitation of mesenteric afferents in the rat. British Journal of Pharmacology. 125: 1352-60. PMID 9863667 DOI: 10.1038/sj.bjp.0702202  0.309
1998 Michel AD, Chessell IP, Hibell AD, Simon J, Humphrey PP. Identification and characterization of an endogenous P2X7 (P2Z) receptor in CHO-K1 cells. British Journal of Pharmacology. 125: 1194-201. PMID 9863647 DOI: 10.1038/sj.bjp.0702205  0.34
1998 Chessell IP, Simon J, Hibell AD, Michel AD, Barnard EA, Humphrey PP. Cloning and functional characterisation of the mouse P2X7 receptor. Febs Letters. 439: 26-30. PMID 9849870 DOI: 10.1016/S0014-5793(98)01332-5  0.388
1998 Smalley KS, Feniuk W, Humphrey PP. Differential agonist activity of somatostatin and L-362855 at human recombinant sst4 receptors. British Journal of Pharmacology. 125: 833-41. PMID 9831922 DOI: 10.1038/sj.bjp.0702133  0.314
1998 Koenig JA, Kaur R, Dodgeon I, Edwardson JM, Humphrey PP. Fates of endocytosed somatostatin sst2 receptors and associated agonists. The Biochemical Journal. 336: 291-8. PMID 9820803  0.365
1998 Schindler M, Kidd EJ, Carruthers AM, Wyatt MA, Jarvie EM, Sellers LA, Feniuk W, Humphrey PP. Molecular cloning and functional characterization of a rat somatostatin sst2(b) receptor splice variant. British Journal of Pharmacology. 125: 209-17. PMID 9776362 DOI: 10.1038/sj.bjp.0702064  0.343
1998 Kidd EJ, Miller KJ, Sansum AJ, Humphrey PP. Evidence for P2X3 receptors in the developing rat brain. Neuroscience. 87: 533-9. PMID 9758220 DOI: 10.1016/S0306-4522(98)00294-2  0.33
1998 Chessell IP, Michel AD, Humphrey PP. Effects of antagonists at the human recombinant P2X7 receptor. British Journal of Pharmacology. 124: 1314-20. PMID 9720806 DOI: 10.1038/sj.bjp.0701958  0.359
1998 Schindler M, Holloway S, Humphrey PP, Waldvogel H, Faull RL, Berger W, Emson PC. Localization of the somatostatin sst2(a) receptor in human cerebral cortex, hippocampus and cerebellum. Neuroreport. 9: 521-5. PMID 9512400  0.319
1998 McQueen DS, Bond SM, Moores C, Chessell I, Humphrey PP, Dowd E. Activation of P2X receptors for adenosine triphosphate evokes cardiorespiratory reflexes in anaesthetized rats. The Journal of Physiology. 507: 843-55. PMID 9508844 DOI: 10.1111/J.1469-7793.1998.843Bs.X  0.302
1997 Lauder H, Sellers LA, Fan TP, Feniuk W, Humphrey PP. Somatostatin sst5 inhibition of receptor mediated regeneration of rat aortic vascular smooth muscle cells. British Journal of Pharmacology. 122: 663-70. PMID 9375962 DOI: 10.1038/sj.bjp.0701443  0.318
1997 Bland-Ward PA, Humphrey PP. Acute nociception mediated by hindpaw P2X receptor activation in the rat. British Journal of Pharmacology. 122: 365-71. PMID 9313948 DOI: 10.1038/sj.bjp.0701371  0.317
1997 Williams AJ, Michel AD, Feniuk W, Humphrey PP. Somatostatin5 receptor-mediated [35S]guanosine-5'-O-(3-thio)triphosphate binding: agonist potencies and the influence of sodium chloride on intrinsic activity. Molecular Pharmacology. 51: 1060-9. PMID 9187273  0.301
1997 Humphrey PP. The characterization and classification of neurotransmitter receptors. Annals of the New York Academy of Sciences. 812: 1-13. PMID 9186716 DOI: 10.1111/j.1749-6632.1997.tb48141.x  0.351
1997 Koenig JA, Edwardson JM, Humphrey PP. Somatostatin receptors in Neuro2A neuroblastoma cells: ligand internalization. British Journal of Pharmacology. 120: 52-9. PMID 9117098 DOI: 10.1038/sj.bjp.0700859  0.313
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