Alistair Mathie, Ph.D. - Publications

Affiliations: 
University of Leicester, Leicester, England, United Kingdom 

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Veale EL, Al-Moubarak E, Bajaria N, Omoto K, Cao L, Tucker SJ, Stevens EB, Mathie A. Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels. Molecular Pharmacology. 85: 671-81. PMID 24509840 DOI: 10.1124/mol.113.091199  1
2014 Veale EL, Hassan M, Walsh Y, Al-Moubarak E, Mathie A. Recovery of current through mutated TASK3 potassium channels underlying birk barel syndrome Molecular Pharmacology. 85: 397-407. PMID 24342771 DOI: 10.1124/mol.113.090530  1
2014 El Hachmane MF, Rees KA, Veale EL, Sumbayev VV, Mathie A. Enhancement of TWIK-related acid-sensitive potassium channel 3 (TASK3) two-pore domain potassium channel activity by tumor necrosis factor α Journal of Biological Chemistry. 289: 1388-1401. PMID 24307172 DOI: 10.1074/jbc.M113.500033  1
2014 Mathie A, Veale EL. Two-pore domain potassium channels: Potential therapeutic targets for the treatment of pain Pflugers Archiv European Journal of Physiology. 467: 931-943. DOI: 10.1007/s00424-014-1655-3  1
2012 Alexander SP, Benson HE, Davenport A, Mathie A, McGrath IJ, Pawson AJ, Peters JA, Sharman JL, Spedding M, Harmar AJ. GuideToPharmacology.org--an update. British Journal of Pharmacology. 167: 697-8. PMID 23003568 DOI: 10.1111/j.1476-5381.2012.02141.x  1
2011 Alexander SP, Mathie A, Peters JA. Guide to Receptors and Channels (GRAC), 5th edition. British Journal of Pharmacology. 164: S1-324. PMID 22040146 DOI: 10.1111/j.1476-5381.2011.01649_1.x  1
2010 Mathie A. Ion channels as novel therapeutic targets in the treatment of pain Journal of Pharmacy and Pharmacology. 62: 1089-1095. PMID 20796186 DOI: 10.1111/j.2042-7158.2010.01131.x  1
2010 Veale EL, Rees KA, Mathie A, Trapp S. Dominant negative effects of a non-conducting TREK1 splice variant expressed in brain Journal of Biological Chemistry. 285: 29295-29304. PMID 20605797 DOI: 10.1074/jbc.M110.108423  1
2010 Mathie A, Al-Moubarak E, Veale EL. Gating of two pore domain potassium channels Journal of Physiology. 588: 3149-3156. PMID 20566661 DOI: 10.1113/jphysiol.2010.192344  1
2010 Mathie A, Rees KA, El Hachmane MF, Veale EL. Trafficking of neuronal two pore domain potassium channels Current Neuropharmacology. 8: 276-286. DOI: 10.2174/157015910792246146  1
2009 Alexander SPH, Mathie A, Peters JA. Guide to Receptors and Channels (GRAC), 4th edition British Journal of Pharmacology. 158: S1. PMID 19883461 DOI: 10.1111/j.1476-5381.2009.00499.x  1
2008 Clarke CE, Veale EL, Wyse K, Vandenberg JI, Mathie A. The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function Journal of Biological Chemistry. 283: 16985-16992. PMID 18417474 DOI: 10.1074/jbc.M801368200  1
2008 Alexander SP, Mathie A, Peters JA. Guide to Receptors and Channels (GRAC), 3rd edition. British Journal of Pharmacology. 153: S1-209. PMID 18347570 DOI: 10.1038/sj.bjp.0707746  1
2007 Veale EL, Buswell R, Clarke CE, Mathie A. Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide British Journal of Pharmacology. 152: 778-786. PMID 17828294 DOI: 10.1038/sj.bjp.0707436  1
2007 Brickley SG, Aller MI, Sandu C, Veale EL, Alder FG, Sambi H, Mathie A, Wisden W. TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9329-40. PMID 17728447 DOI: 10.1523/JNEUROSCI.1427-07.2007  1
2007 Mathie A, Veale EL. Therapeutic potential of neuronal two-pore domain potassium-channel modulators Current Opinion in Investigational Drugs. 8: 555-562. PMID 17659475  1
2007 Veale EL, Kennard LE, Sutton GL, MacKenzie G, Sandu C, Mathie A. G(alpha)q-mediated regulation of TASK3 two-pore domain potassium channels: the role of protein kinase C. Molecular Pharmacology. 71: 1666-75. PMID 17374744 DOI: 10.1124/mol.106.033241  1
2007 Alexander SP, Mathie A, Peters JA. Guide to Receptors and Channels (GRAC), 2nd edition (2007 Revision). British Journal of Pharmacology. 150: S1-168. PMID 17279063 DOI: 10.1038/sj.bjp.0707199  1
2007 Mathie A. Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors Journal of Physiology. 578: 377-385. PMID 17068099 DOI: 10.1113/jphysiol.2006.121582  1
2006 Alexander SP, Mathie A, Peters JA. Guide to receptors and channels, 2nd edition. British Journal of Pharmacology. 147: S1-168. PMID 16550176 DOI: 10.1038/sj.bjp.0706651  1
2006 Mathie A, Sutton GL, Clarke CE, Veale EL. Zinc and copper: Pharmacological probes and endogenous modulators of neuronal excitability Pharmacology and Therapeutics. 111: 567-583. PMID 16410023 DOI: 10.1016/j.pharmthera.2005.11.004  1
2006 Linden AM, Aller MI, Leppä E, Vekovischeva O, Aitta-Aho T, Veale EL, Mathie A, Rosenberg P, Wisden W, Korpi ER. The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists. The Journal of Pharmacology and Experimental Therapeutics. 317: 615-26. PMID 16397088 DOI: 10.1124/jpet.105.098525  1
2005 Aller MI, Veale EL, Linden AM, Sandu C, Schwaninger M, Evans LJ, Korpi ER, Mathie A, Wisden W, Brickley SG. Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11455-67. PMID 16339039 DOI: 10.1523/JNEUROSCI.3153-05.2005  1
2005 Alexander SP, Mathie A, Peters JA. Guide to receptors and channels, 1st edition (2005 revision). British Journal of Pharmacology. 144: S1-128. PMID 15793590 DOI: 10.1038/sj.bjp.0706158  1
2005 Kennard LE, Chumbley JR, Ranatunga KM, Armstrong SJ, Veale EL, Mathie A. Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine British Journal of Pharmacology. 144: 821-829. PMID 15685212 DOI: 10.1038/sj.bjp.0706068  1
2004 Gruss M, Mathie A, Lieb WR, Franks NP. The two-pore-domain K(+) channels TREK-1 and TASK-3 are differentially modulated by copper and zinc. Molecular Pharmacology. 66: 530-7. PMID 15322244 DOI: 10.1124/mol.66.3.  1
2004 Clarke CE, Veale EL, Green PJ, Meadows HJ, Mathie A. Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zinc Journal of Physiology. 560: 51-62. PMID 15284350 DOI: 10.1113/jphysiol.2004.070292  1
2004 Alexander SP, Mathie A, Peters JA. Guide to receptors and channels, 1st edition. British Journal of Pharmacology. 141: S1-126. PMID 15082510 DOI: 10.1038/sj.bjp.0705672  1
2004 Gruss M, Bushell TJ, Bright DP, Lieb WR, Mathie A, Franks NP. Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane. Molecular Pharmacology. 65: 443-52. PMID 14742687 DOI: 10.1124/mol.65.2.443  1
2003 Mathie A, Kennard LE, Veale EL. Neuronal ion channells and their sensitivity to extremely low frequency weak electric field effects Radiation Protection Dosimetry. 106: 311-316. PMID 14690272  1
2003 Mathie A, Clarke CE, Ranatunga KM, Veale EL. What are the roles of the many different types of potassium channel expressed in cerebellar granule cells? Cerebellum. 2: 11-25. PMID 12882230 DOI: 10.1080/14734220309429  1
2002 Mathie A, Clarke CE. Background potassium channels move into focus Journal of Physiology. 542: 334. PMID 12122133 DOI: 10.1013/jphysiol.2002.020008  1
2002 Bushell T, Clarke C, Mathie A, Robertson B. Pharmacological characterization of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones. British Journal of Pharmacology. 135: 705-12. PMID 11834618 DOI: 10.1038/sj.bjp.0704518  1
2002 Boyd DF, Mathie A. Inhibition of the potassium current IKSO, in cerebellar granule cells, by the inhibitors of MEK1 activation, PD 98059 and U 0126 Neuropharmacology. 42: 221-228. PMID 11804618 DOI: 10.1016/S0028-3908(01)00168-X  1
2000 Boyd DF, Millar JA, Watkins CS, Mathie A. The role of Ca2+ stores in the muscarinic inhibition of the K+ current IK(SO) in neonatal rat cerebellar granule cells. The Journal of Physiology. 529: 321-31. PMID 11101643 DOI: 10.1111/j.1469-7793.2000.00321.x  1
2000 Prothero LS, Mathie A, Richards CD. Purinergic and muscarinic receptor activation activates a common calcium entry pathway in rat neocortical neurons and glial cells Neuropharmacology. 39: 1768-1778. PMID 10884558 DOI: 10.1016/S0028-3908(00)00013-7  1
2000 Jones G, Boyd DF, Yeung SY, Mathie A. Inhibition of delayed rectifier K+ conductance in cultured rat cerebellar granule neurons by activation of calcium-permeable AMPA receptors European Journal of Neuroscience. 12: 935-944. PMID 10762323 DOI: 10.1046/j.1460-9568.2000.00983.x  1
2000 Millar JA, Barratt L, Southan AP, Page KM, Fyffe RE, Robertson B, Mathie A. A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons. Proceedings of the National Academy of Sciences of the United States of America. 97: 3614-8. PMID 10725353 DOI: 10.1073/pnas.050012597  1
1999 Yeung SY, Millar JA, Mathie A. Inhibition of neuronal K(v) potassium currents by the antidepressant drug, fluoxetine British Journal of Pharmacology. 128: 1609-1615. PMID 10602343  1
1998 Prothero LS, Richards CD, Mathie A. Inhibition by inorganic ions of a sustained calcium signal evoked by activation of mGlu5 receptors in rat cortical neurons and glia British Journal of Pharmacology. 125: 1551-1561. PMID 9884084  1
1998 Amos BJ, Mathie A, Richards CD. Activation of group I metabotropic glutamate receptors elicits pH changes in cultured rat cortical glia and neurons Neuroscience. 86: 1109-1120. PMID 9697118 DOI: 10.1016/S0306-4522(98)00072-4  1
1998 Clark S, Jordt SE, Jentsch TJ, Mathie A. Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons. The Journal of Physiology. 506: 665-78. PMID 9503329 DOI: 10.1111/j.1469-7793.1998.665bv.x  1
1998 Mathie A, Wooltorton JRA, Watkins CS. Voltage-activated potassium channels in mammalian neurons and their block by novel pharmacological agents General Pharmacology. 30: 13-24. DOI: 10.1016/S0306-3623(97)00034-7  1
1997 Mathie A, Watkins CS. Is EAG the answer to the M-current? Trends in Neurosciences. 20: 14. PMID 9004413 DOI: 10.1016/S0166-2236(96)20057-8  1
1996 Watkins CS, Mathie A. A non-inactivating K+ current sensitive to muscarinic receptor activation in rat cultured cerebellar granule neurons Journal of Physiology. 491: 401-412. PMID 8866863  1
1996 Watkins CS, Mathie A. Effects on K+ currents in rat cerebellar granule neurones of a membrane-permeable analogue of the calcium chelator BAPTA British Journal of Pharmacology. 118: 1772-1778. PMID 8842443  1
1995 Hille B, Beech DJ, Bernheim L, Mathie A, Shapiro MS, Wollmuth LP. Multiple G-protein-coupled pathways inhibit N-type Ca channels of neurons. Life Sciences. 56: 989-92. PMID 10188803 DOI: 10.1016/0024-3205(95)00038-8  1
1995 Wooltorton JR, Mathie A. Potent block of potassium currents in rat isolated sympathetic neurones by the uncharged form of amitriptyline and related tricyclic compounds. British Journal of Pharmacology. 116: 2191-200. PMID 8564248  1
1994 Watkins CS, Mathie A. Modulation of the gating of the transient outward potassium current of rat isolated cerebellar granule neurons by lanthanum PflüGers Archiv European Journal of Physiology. 428: 209-216. PMID 7816543 DOI: 10.1007/BF00724499  1
1993 Wooltorton JR, Mathie A. Block of potassium currents in rat isolated sympathetic neurones by tricyclic antidepressants and structurally related compounds. British Journal of Pharmacology. 110: 1126-32. PMID 8298801  1
1993 Watkins CS, Mathie A. The modulation by lanthanum of the gating of voltage-dependent potassium currents in rat isolated cerebellar granule neurones Journal of Physiology. 473: 160P.  1
1992 Yang J, Mathie A, Hille B. 5-HT3 receptor channels in dissociated rat superior cervical ganglion neurons. The Journal of Physiology. 448: 237-56. PMID 1375636  1
1992 Bernheim L, Mathie A, Hille B. Characterization of muscarinic receptor subtypes inhibiting Ca2+ current and M current in rat sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 89: 9544-8. PMID 1329101  1
1992 Mathie A, Bernheim L, Hille B. Inhibition of N- and L-type calcium channels by muscarinic receptor activation in rat sympathetic neurons. Neuron. 8: 907-14. PMID 1316767 DOI: 10.1016/0896-6273(92)90205-R  1
1992 Mathie A, Bernheim L, Hille B. Classification of muscarinic receptors inhibiting calcium current and M current in dissociated rat superior cervical ganglion (SCG) neurons Journal of Physiology. 446: 548P.  1
1991 Beech DJ, Bernheim L, Mathie A, Hille B. Intracellular Ca2+ buffers disrupt muscarinic suppression of Ca2+ current and M current in rat sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 88: 652-6. PMID 1846449  1
1991 Mathie A, Cull-Candy SG, Colquhoun D. Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones. The Journal of Physiology. 439: 717-50. PMID 1716680  1
1991 Wyllie DJ, Mathie A, Symonds CJ, Cull-Candy SG. Activation of glutamate receptors and glutamate uptake in identified macroglial cells in rat cerebellar cultures. The Journal of Physiology. 432: 235-58. PMID 1653320  1
1990 Colquhoun D, Cachelin AB, Marshall CG, Mathie A, Ogden DC. Function of nicotinic synapses. Progress in Brain Research. 84: 43-50. PMID 2267314  1
1990 Mathie A, Colquhoun D, Cull-Candy SG. Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones. The Journal of Physiology. 427: 625-55. PMID 1698982  1
1989 Colquhoun D, Mathie A, Mulrine NK, Ogden DC. Studies on single acetylcholine-receptor channels in muscle end-plate and sympathetic neurones Fernstrom Foundation Series. 13: 217-234.  1
1988 Cull-Candy SG, Mathie A, Powis DA. Acetylcholine receptor channels and their block by clonidine in cultured bovine chromaffin cells. The Journal of Physiology. 402: 255-78. PMID 2466982  1
1987 Mathie A, Cull-Candy SG, Colquhoun D. Single-channel and whole-cell currents evoked by acetylcholine in dissociated sympathetic neurons of the rat. Proceedings of the Royal Society of London. Series B, Biological Sciences. 232: 239-48. PMID 2892208  1
1987 Colquhoun D, Ogden DC, Mathie A. Nicotinic acetylcholine receptors of nerve and muscle: Functional aspects Trends in Pharmacological Sciences. 8: 465-472. DOI: 10.1016/0165-6147(87)90040-X  1
1986 Blakeley AG, Mathie A, Petersen SA. Interactions between the effects of yohimbine, clonidine and [Ca]o on the electrical response of the mouse vas deferens. British Journal of Pharmacology. 88: 807-14. PMID 3742159 DOI: 10.1111/j.1476-5381.1986.tb16253.x  1
1986 Cull-Candy SG, Mathie A. Ion channels activated by acetylcholine and gamma-aminobutyric acid in freshly dissociated sympathetic neurones of the rat. Neuroscience Letters. 66: 275-80. PMID 2425288 DOI: 10.1016/0304-3940(86)90031-5  1
1984 Blakeley AG, Cunnane TC, Maskell T, Mathie A, Petersen SA. Alpha-adrenoceptors and facilitation at a sympathetic neuroeffector junction. Journal of Autonomic Pharmacology. 4: 53-8. PMID 6325465 DOI: 10.1111/j.1474-8673.1984.tb00433.x  0.68
1984 Blakeley AG, Mathie A, Petersen SA. Facilitation at single release sites of a sympathetic neuroeffector junction in the mouse. The Journal of Physiology. 349: 57-71. PMID 6145793 DOI: 10.1113/jphysiol.1984.sp015142  1
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