Emilia Entcheva - Publications

Affiliations: 
Biomedical Engineering George Washington University, Washington, DC, United States 
Area:
Optogenetics, optical mapping, cardiac electrophysiology

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Heinson YW, Han JL, Entcheva E. OptoDyCE-plate as an affordable high throughput imager for all optical cardiac electrophysiology. Journal of Molecular and Cellular Cardiology Plus. 6. PMID 38130942 DOI: 10.1016/j.jmccpl.2023.100054  0.808
2023 Han JL, Heinson YW, Chua CJ, Liu W, Entcheva E. CRISPRi gene modulation and all-optical electrophysiology in post-differentiated human iPSC-cardiomyocytes. Communications Biology. 6: 1236. PMID 38062109 DOI: 10.1038/s42003-023-05627-y  0.813
2023 Song Q, Alvarez-Laviada A, Schrup SE, Reilly-O'Donnell B, Entcheva E, Gorelik J. Opto-SICM framework combines optogenetics with scanning ion conductance microscopy for probing cell-to-cell contacts. Communications Biology. 6: 1131. PMID 37938652 DOI: 10.1038/s42003-023-05509-3  0.328
2023 Heinson YW, Han JL, Entcheva E. OptoDyCE-plate as an affordable high throughput imager for all optical cardiac electrophysiology. Biorxiv : the Preprint Server For Biology. PMID 37693544 DOI: 10.1101/2023.08.29.555447  0.809
2023 Li W, McLeod D, Ketzenberger JT, Kowalik G, Russo R, Li Z, Kay MW, Entcheva E. High-throughput optical sensing of peri-cellular oxygen in cardiac cells: system characterization, calibration, and testing. Frontiers in Bioengineering and Biotechnology. 11: 1214493. PMID 37397961 DOI: 10.3389/fbioe.2023.1214493  0.623
2023 Han JL, Heinson YW, Chua CJ, Liu W, Entcheva E. CRISPRi Gene Modulation and All-Optical Electrophysiology in Post-Differentiated Human iPSC-Cardiomyocytes. Biorxiv : the Preprint Server For Biology. PMID 37214814 DOI: 10.1101/2023.05.07.539756  0.813
2023 Li W, McLeod D, Ketzenberger JT, Kowalik G, Russo R, Li Z, Kay MW, Entcheva E. High-throughput optical sensing of peri-cellular oxygen in cardiac cells: system characterization, calibration, and testing. Biorxiv : the Preprint Server For Biology. PMID 37163022 DOI: 10.1101/2023.04.24.538133  0.623
2023 Liu W, Han JL, Tomek J, Bub G, Entcheva E. Simultaneous Widefield Voltage and Dye-Free Optical Mapping Quantifies Electromechanical Waves in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Acs Photonics. 10: 1070-1083. PMID 37096210 DOI: 10.1021/acsphotonics.2c01644  0.807
2023 Han JL, Entcheva E. Gene Modulation with CRISPR-based Tools in Human iPSC-Cardiomyocytes. Stem Cell Reviews and Reports. PMID 36656467 DOI: 10.1007/s12015-023-10506-4  0.801
2023 Heinson YW, Han JL, Entcheva E. Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology. Journal of Biomedical Optics. 28: 016001. PMID 36636698 DOI: 10.1117/1.JBO.28.1.016001  0.824
2022 Pressler MP, Horvath A, Entcheva E. Sex-dependent transcription of cardiac electrophysiology and links to acetylation modifiers based on the GTEx database. Frontiers in Cardiovascular Medicine. 9: 941890. PMID 35935618 DOI: 10.3389/fcvm.2022.941890  0.385
2022 Li W, Han JL, Entcheva E. Protein and mRNA Quantification in Small Samples of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in 96-Well Microplates. Methods in Molecular Biology (Clifton, N.J.). 2485: 15-37. PMID 35618896 DOI: 10.1007/978-1-0716-2261-2_2  0.785
2022 Pozo MR, Meredith GW, Entcheva E. Human iPSC-Cardiomyocytes as an Experimental Model to Study Epigenetic Modifiers of Electrophysiology. Cells. 11. PMID 35053315 DOI: 10.3390/cells11020200  0.737
2021 Müllenbroich MC, Kelly A, Acker C, Bub G, Bruegmann T, Di Bona A, Entcheva E, Ferrantini C, Kohl P, Lehnart SE, Mongillo M, Parmeggiani C, Richter C, Sasse P, Zaglia T, et al. Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review. Frontiers in Physiology. 12: 769586. PMID 34867476 DOI: 10.3389/fphys.2021.769586  0.51
2021 Chua CJ, Han JL, Li W, Liu W, Entcheva E. Integration of Engineered "Spark-Cell" Spheroids for Optical Pacing of Cardiac Tissue. Frontiers in Bioengineering and Biotechnology. 9: 658594. PMID 34222210 DOI: 10.3389/fbioe.2021.658594  0.826
2021 Boyle PM, Yu J, Klimas A, Williams JC, Trayanova NA, Entcheva E. OptoGap is an optogenetics-enabled assay for quantification of cell-cell coupling in multicellular cardiac tissue. Scientific Reports. 11: 9310. PMID 33927252 DOI: 10.1038/s41598-021-88573-1  0.819
2021 Kostecki GM, Shi Y, Chen CS, Reich DH, Entcheva E, Tung L. Optogenetic current in myofibroblasts acutely alters electrophysiology and conduction of co-cultured cardiomyocytes. Scientific Reports. 11: 4430. PMID 33627695 DOI: 10.1038/s41598-021-83398-4  0.615
2020 Entcheva E, Kay MW. Cardiac optogenetics: a decade of enlightenment. Nature Reviews. Cardiology. PMID 33340010 DOI: 10.1038/s41569-020-00478-0  0.491
2020 Wei L, Li W, Entcheva E, Li Z. Microfluidics-enabled 96-well perfusion system for high-throughput tissue engineering and long-term all-optical electrophysiology. Lab On a Chip. PMID 32996969 DOI: 10.1039/d0lc00615g  0.659
2020 Li W, Han JL, Entcheva E. Syncytium cell growth increases Kir2.1 contribution in human iPSC-cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32986966 DOI: 10.1152/ajpheart.00148.2020  0.823
2020 Burton RB, Tomek J, Ambrosi CM, Larsen HE, Sharkey AR, Capel RA, Corbett AD, Bilton S, Klimas A, Stephens G, Cremer M, Bose SJ, Li D, Gallone G, Herring N, ... ... Entcheva E, et al. Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics. Iscience. 23: 101334. PMID 32674058 DOI: 10.1016/j.isci.2020.101334  0.801
2020 Paci M, Passini E, Klimas A, Severi S, Hyttinen J, Rodriguez B, Entcheva E. All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation. Biophysical Journal. PMID 32298635 DOI: 10.1016/j.bpj.2020.03.018  0.781
2019 Schultz F, Swiatlowska P, Alvarez-Laviada A, Sanchez-Alonso JL, Song Q, de Vries AAF, Pijnappels DA, Ongstad E, Braga VMM, Entcheva E, Gourdie RG, Miragoli M, Gorelik J. Cardiomyocyte-myofibroblast contact dynamism is modulated by connexin-43. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802740RR. PMID 31253057 DOI: 10.1096/Fj.201802740Rr  0.318
2019 Ambrosi CM, Sadananda G, Han JL, Entcheva E. Adeno-Associated Virus Mediated Gene Delivery: Implications for Scalable and Cardiac Optogenetic Models. Frontiers in Physiology. 10: 168. PMID 30890951 DOI: 10.3389/fphys.2019.00168  0.823
2019 Klimas A, Ortiz G, Boggess SC, Miller EW, Entcheva E. Multimodal on-axis platform for all-optical electrophysiology with near-infrared probes in human stem-cell-derived cardiomyocytes. Progress in Biophysics and Molecular Biology. PMID 30850184 DOI: 10.1016/J.Pbiomolbio.2019.02.004  0.805
2018 Quach B, Krogh-Madsen T, Entcheva E, Christini DJ. Light-Activated Dynamic Clamp Using iPSC-Derived Cardiomyocytes. Biophysical Journal. 115: 2206-2217. PMID 30447994 DOI: 10.1016/j.bpj.2018.10.018  0.364
2018 Singh T, Castellanos IS, Haar S, Klimas A, Entcheva E, Salvador T, Bhowmick DC, Cohen J, Cleary K, Jeremic A, Zderic V. Ultrasound-Induced Insulin Release as a Potential Novel Treatmentfor Type 2 Diabetes Mellitus. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2018: 6060-6063. PMID 30441718 DOI: 10.1109/EMBC.2018.8513687  0.258
2018 Entcheva E. Uncovering an electrically heterogeneous cardiomyocyte by FRAP-quantified diffusion in the T-tubules. Proceedings of the National Academy of Sciences of the United States of America. 115: E560-E561. PMID 29306861 DOI: 10.1073/pnas.1719550115  0.241
2016 Klimas A, Ambrosi CM, Yu J, Williams JC, Bien H, Entcheva E. OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology. Nature Communications. 7: 11542. PMID 27161419 DOI: 10.1038/ncomms11542  0.806
2016 Yu J, Entcheva E. Inscribing Optical Excitability to Non-Excitable Cardiac Cells: Viral Delivery of Optogenetic Tools in Primary Cardiac Fibroblasts. Methods in Molecular Biology (Clifton, N.J.). 1408: 303-17. PMID 26965132 DOI: 10.1007/978-1-4939-3512-3_21  0.838
2016 Entcheva E, Bub G. All-optical control of cardiac excitation: combined high-resolution optogenetic actuation and optical mapping. The Journal of Physiology. 594: 2503-10. PMID 26857427 DOI: 10.1113/JP271559  0.522
2015 Burton RA, Klimas A, Ambrosi CM, Tomek J, Corbett A, Entcheva E, Bub G. Optical control of excitation waves in cardiac tissue. Nature Photonics. 9: 813-816. PMID 27057206 DOI: 10.1038/Nphoton.2015.196  0.816
2015 Ambrosi CM, Boyle PM, Chen K, Trayanova NA, Entcheva E. Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability. Scientific Reports. 5: 17350. PMID 26621212 DOI: 10.1038/Srep17350  0.769
2015 Yu J, Chen K, Lucero RV, Ambrosi CM, Entcheva E. Cardiac Optogenetics: Enhancement by All-trans-Retinal. Scientific Reports. 5: 16542. PMID 26568132 DOI: 10.1038/Srep16542  0.828
2015 Boyle PM, Karathanos TV, Entcheva E, Trayanova NA. Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations. Computers in Biology and Medicine. 65: 200-8. PMID 26002074 DOI: 10.1016/J.Compbiomed.2015.04.036  0.515
2015 Williams JC, Entcheva E. Optogenetic versus Electrical Stimulation of Human Cardiomyocytes: Modeling Insights. Biophysical Journal. 108: 1934-45. PMID 25902433 DOI: 10.1016/j.bpj.2015.03.032  0.581
2015 Entcheva E. A step closer to cardiac optogenetics in vivo. Cardiovascular Research. 106: 180-1. PMID 25808975 DOI: 10.1093/cvr/cvv116  0.447
2015 Klimas A, Entcheva E. Toward microendoscopy-inspired cardiac optogenetics in vivo: technical overview and perspective. Journal of Biomedical Optics. 19: 080701. PMID 25117076 DOI: 10.1117/1.JBO.19.8.080701  0.829
2014 Ambrosi CM, Entcheva E. Optogenetic control of cardiomyocytes via viral delivery. Methods in Molecular Biology (Clifton, N.J.). 1181: 215-28. PMID 25070340 DOI: 10.1007/978-1-4939-1047-2_19  0.778
2014 Entcheva E, Williams JC. Channelrhodopsin2 current during the action potential: "optical AP clamp" and approximation. Scientific Reports. 4: 5838. PMID 25060859 DOI: 10.1038/srep05838  0.529
2014 Ambrosi CM, Klimas A, Yu J, Entcheva E. Cardiac applications of optogenetics. Progress in Biophysics and Molecular Biology. 115: 294-304. PMID 25035999 DOI: 10.1016/J.Pbiomolbio.2014.07.001  0.834
2014 Wu CY, Chen B, Jiang YP, Jia Z, Martin DW, Liu S, Entcheva E, Song LS, Lin RZ. Calpain-dependent cleavage of junctophilin-2 and T-tubule remodeling in a mouse model of reversible heart failure. Journal of the American Heart Association. 3: e000527. PMID 24958777 DOI: 10.1161/JAHA.113.000527  0.764
2014 Entcheva E. Fiat lux in understanding cardiac pacing, resynchronization and signalling by way of optogenetics. Cardiovascular Research. 102: 342-3. PMID 24760549 DOI: 10.1093/cvr/cvu109  0.403
2014 Ambrosi CM, Entcheva E. Optogenetics' promise: pacing and cardioversion by light? Future Cardiology. 10: 1-4. PMID 24344652 DOI: 10.2217/Fca.13.89  0.718
2014 Boyle PM, Entcheva E, Trayanova NA. See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort? Expert Review of Cardiovascular Therapy. 12: 17-20. PMID 24308809 DOI: 10.1586/14779072.2014.864951  0.489
2013 Williams JC, Xu J, Lu Z, Klimas A, Chen X, Ambrosi CM, Cohen IS, Entcheva E. Computational optogenetics: empirically-derived voltage- and light-sensitive channelrhodopsin-2 model. Plos Computational Biology. 9: e1003220. PMID 24068903 DOI: 10.1371/Journal.Pcbi.1003220  0.818
2013 Boyle PM, Williams JC, Ambrosi CM, Entcheva E, Trayanova NA. A comprehensive multiscale framework for simulating optogenetics in the heart. Nature Communications. 4: 2370. PMID 23982300 DOI: 10.1038/Ncomms3370  0.819
2013 Entcheva E. Cardiac optogenetics. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1179-91. PMID 23457014 DOI: 10.1152/ajpheart.00432.2012  0.501
2012 Boink GJ, Lu J, Driessen HE, Duan L, Sosunov EA, Anyukhovsky EP, Shlapakova IN, Lau DH, Rosen TS, Danilo P, Jia Z, Ozgen N, Bobkov Y, Guo Y, Brink PR, ... ... Entcheva E, et al. Effect of skeletal muscle Na(+) channel delivered via a cell platform on cardiac conduction and arrhythmia induction. Circulation. Arrhythmia and Electrophysiology. 5: 831-40. PMID 22722661 DOI: 10.1161/Circep.111.969907  0.797
2012 Lu J, Wang HZ, Jia Z, Zuckerman J, Lu Z, Guo Y, Boink GJ, Brink PR, Robinson RB, Entcheva E, Cohen IS. Improving cardiac conduction with a skeletal muscle sodium channel by gene and cell therapy. Journal of Cardiovascular Pharmacology. 60: 88-99. PMID 22526298 DOI: 10.1097/Fjc.0B013E3182588B00  0.813
2012 Jia Z, Bien H, Shiferaw Y, Entcheva E. Cardiac cellular coupling and the spread of early instabilities in intracellular Ca2+. Biophysical Journal. 102: 1294-302. PMID 22455912 DOI: 10.1016/J.Bpj.2012.02.034  0.79
2011 Wu CY, Jia Z, Wang W, Ballou LM, Jiang YP, Chen B, Mathias RT, Cohen IS, Song LS, Entcheva E, Lin RZ. PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes. Plos One. 6: e24404. PMID 21912691 DOI: 10.1371/Journal.Pone.0024404  0.786
2011 Jia Z, Valiunas V, Lu Z, Bien H, Liu H, Wang HZ, Rosati B, Brink PR, Cohen IS, Entcheva E. Stimulating cardiac muscle by light: cardiac optogenetics by cell delivery. Circulation. Arrhythmia and Electrophysiology. 4: 753-60. PMID 21828312 DOI: 10.1161/Circep.111.964247  0.837
2011 Leigh SY, Tattu A, Mitchell JS, Entcheva E. M³: Microscope-based maskless micropatterning with dry film photoresist. Biomedical Microdevices. 13: 375-81. PMID 21190086 DOI: 10.1007/s10544-010-9506-2  0.661
2011 Chung CY, Bien H, Sobie EA, Dasari V, McKinnon D, Rosati B, Entcheva E. Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self-organization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 851-62. PMID 21084696 DOI: 10.1096/Fj.10-168625  0.82
2010 Hörning M, Isomura A, Jia Z, Entcheva E, Yoshikawa K. Utilizing the eikonal relationship in strategies for reentrant wave termination in excitable media. Physical Review E. 81: 56202-56202. PMID 20866302 DOI: 10.1103/Physreve.81.056202  0.763
2010 Wang W, Gao J, Entcheva E, Cohen IS, Gordon C, Mathias RT. A transmural gradient in the cardiac Na/K pump generates a transmural gradient in Na/Ca exchange. The Journal of Membrane Biology. 233: 51-62. PMID 20130849 DOI: 10.1007/S00232-010-9224-Y  0.281
2009 Entcheva E, Bien H. Mechanical and spatial determinants of cytoskeletal geodesic dome formation in cardiac fibroblasts. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 212-9. PMID 20023805 DOI: 10.1039/b818874b  0.754
2009 Jia Z, Bien H, Entcheva E. Detecting space-time alternating biological signals close to the bifurcation point. Ieee Transactions On Bio-Medical Engineering. 57: 316-24. PMID 19695992 DOI: 10.1109/TBME.2009.2028652  0.785
2009 Lu Z, Jiang YP, Wang W, Xu XH, Mathias RT, Entcheva E, Ballou LM, Cohen IS, Lin RZ. Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction. Circulation. 120: 318-25. PMID 19597047 DOI: 10.1161/Circulationaha.109.873380  0.372
2009 Jia Z, Bien H, Entcheva E. A sensitive algorithm for automatic detection of space-time alternating signals in cardiac tissue. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2008: 153-6. PMID 19162616 DOI: 10.1109/IEMBS.2008.4649113  0.804
2009 Protas L, Dun W, Jia Z, Lu J, Bucchi A, Kumari S, Chen M, Cohen IS, Rosen MR, Entcheva E, Robinson RB. Expression of skeletal but not cardiac Na+ channel isoform preserves normal conduction in a depolarized cardiac syncytium. Cardiovascular Research. 81: 528-35. PMID 18977767 DOI: 10.1093/Cvr/Cvn290  0.777
2008 Bartocci E, Corradini F, Entcheva E, Grosu R, Smolka SA. CellExcite: an efficient simulation environment for excitable cells. Bmc Bioinformatics. 9: S3. PMID 18387205 DOI: 10.1186/1471-2105-9-S2-S3  0.597
2008 Shah U, Bien H, Entcheva E. Cardiac arrhythmogenesis and temperature. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2006: 841-4. PMID 17946861 DOI: 10.1109/IEMBS.2006.260090  0.784
2007 Chung CY, Bien H, Entcheva E. The role of cardiac tissue alignment in modulating electrical function. Journal of Cardiovascular Electrophysiology. 18: 1323-9. PMID 17916158 DOI: 10.1111/j.1540-8167.2007.00959.x  0.822
2007 Bien H, Parikh P, Entcheva E. Lenses and effective spatial resolution in macroscopic optical mapping. Physics in Medicine and Biology. 52: 941-60. PMID 17264363 DOI: 10.1088/0031-9155/52/4/006  0.8
2006 Singh R, Bien H, Entcheva E, Fenton FF. Inherent dispersion in restitution properties over space. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 3935-8. PMID 17947060 DOI: 10.1109/IEMBS.2006.260425  0.814
2006 Bien H, Entcheva E. Spatial frequency content in optical mapping of cardiac cell monolayers. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1484; author reply . PMID 16714358 DOI: 10.1152/ajpheart.00433.2006  0.77
2006 Bien H, Yin L, Entcheva E. Calcium instabilities in mammalian cardiomyocyte networks. Biophysical Journal. 90: 2628-40. PMID 16399841 DOI: 10.1529/biophysj.105.063321  0.804
2005 Entcheva E, Bien H. Macroscopic optical mapping of excitation in cardiac cell networks with ultra-high spatiotemporal resolution. Progress in Biophysics and Molecular Biology. 92: 232-57. PMID 16330086 DOI: 10.1016/j.pbiomolbio.2005.10.003  0.8
2005 Zong X, Bien H, Chung CY, Yin L, Fang D, Hsiao BS, Chu B, Entcheva E. Electrospun fine-textured scaffolds for heart tissue constructs. Biomaterials. 26: 5330-8. PMID 15814131 DOI: 10.1016/J.Biomaterials.2005.01.052  0.804
2005 Entcheva E, Bien H, Yin L, Chung CY, Farrell M, Kostov Y. Functional cardiac cell constructs on cellulose-based scaffolding. Biomaterials. 25: 5753-62. PMID 15147821 DOI: 10.1016/j.biomaterials.2004.01.024  0.818
2004 Entcheva E, Bien H. Acoustic micromachining of three-dimensional surfaces for biological applications. Lab On a Chip. 5: 179-83. PMID 15672132 DOI: 10.1039/b409478f  0.715
2004 Yin L, Bien H, Entcheva E. Scaffold topography alters intracellular calcium dynamics in cultured cardiomyocyte networks. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1276-85. PMID 15105172 DOI: 10.1152/ajpheart.01120.2003  0.785
2004 Entcheva E, Kostov Y, Tchernev E, Tung L. Fluorescence imaging of electrical activity in cardiac cells using an all-solid-state system. Ieee Transactions On Bio-Medical Engineering. 51: 333-41. PMID 14765706 DOI: 10.1109/Tbme.2003.820376  0.611
2004 Bien H, Yin L, Entcheva E. Cardiac cell networks on elastic microgrooved scaffolds. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 22: 108-12. PMID 14699943 DOI: 10.1109/memb.2003.1256279  0.802
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