Michael T. Hemann, Ph.D.

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Telomeres and telomerase in chromosome maintenance and stability
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"Michael Hemann"

Parents

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Carol W. Greider grad student 2002 Johns Hopkins
 (Analysis of telomere dysfunction in mouse.)

Children

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Yadira Marie Soto-Feliciano grad student 2010-2016 MIT (Microtree)
Simona Dalin grad student 2014-2019 (Neurotree)
Azucena Ramos grad student 2015-2020 MIT
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Publications

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Ramos A, Koch CE, Liu-Lupo Y, et al. (2023) Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening. Nature Communications. 14: 8048
Liu-Lupo Y, Ham JD, Jeewajee SKA, et al. (2023) Integrated multi-omics analyses reveal homology-directed repair pathway as a unique dependency in near-haploid leukemia. Blood Cancer Journal. 13: 92
Gordon KS, Kyung T, Perez CR, et al. (2023) Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains. Nature Biomedical Engineering
Gordon KS, Kyung T, Perez CR, et al. (2022) Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains. Nature Biomedical Engineering
Dalin S, Grauman-Boss B, Lauffenburger DA, et al. (2022) Collateral responses to classical cytotoxic chemotherapies are heterogeneous and sensitivities are sparse. Scientific Reports. 12: 5453
Mueller HS, Fowler CE, Dalin S, et al. (2021) Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel. Proceedings of the National Academy of Sciences of the United States of America. 118
Sánchez-Rivera FJ, Ryan J, Soto-Feliciano YM, et al. (2021) Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration. Proceedings of the National Academy of Sciences of the United States of America. 118
Roux B, Vaganay C, Vargas JD, et al. (2021) Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. Science Translational Medicine. 13
Jiang T, Sánchez-Rivera FJ, Soto-Feliciano YM, et al. (2020) Targeting de novo purine synthesis pathway via ADSL depletion impairs liver cancer growth by perturbing mitochondrial function. Hepatology (Baltimore, Md.)
Chatterjee N, Whitman MA, Harris CA, et al. (2020) REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. Proceedings of the National Academy of Sciences of the United States of America
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