Michael T. Hemann, Ph.D.

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Telomeres and telomerase in chromosome maintenance and stability
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"Michael Hemann"

Parents

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Carol W. Greider grad student 2002 Johns Hopkins
 (Analysis of telomere dysfunction in mouse.)

Children

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Yadira Marie Soto-Feliciano grad student 2010-2016 MIT (Microtree)
Simona Dalin grad student 2014-2019 (Neurotree)
Azucena Ramos grad student 2015-2020 MIT
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Publications

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Mueller HS, Fowler CE, Dalin S, et al. (2021) Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel. Proceedings of the National Academy of Sciences of the United States of America. 118
Sánchez-Rivera FJ, Ryan J, Soto-Feliciano YM, et al. (2021) Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration. Proceedings of the National Academy of Sciences of the United States of America. 118
Roux B, Vaganay C, Vargas JD, et al. (2021) Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. Science Translational Medicine. 13
Jiang T, Sánchez-Rivera FJ, Soto-Feliciano YM, et al. (2020) Targeting de novo purine synthesis pathway via ADSL depletion impairs liver cancer growth by perturbing mitochondrial function. Hepatology (Baltimore, Md.)
Chatterjee N, Whitman MA, Harris CA, et al. (2020) REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. Proceedings of the National Academy of Sciences of the United States of America
Vassel FM, Bian K, Walker GC, et al. (2020) Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer. Proceedings of the National Academy of Sciences of the United States of America
Liu Y, Shi N, Regev A, et al. (2020) Integrated regulatory models for inference of subtype-specific susceptibilities in glioblastoma. Molecular Systems Biology. 16: e9506
Kong YW, Dreaden EC, Morandell S, et al. (2020) Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints. Nature Communications. 11: 4124
Qi R, Wang Y, Bruno PM, et al. (2020) Author Correction: Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer. Nature Communications. 11: 1940
Bruno PM, Lu M, Dennis KA, et al. (2020) The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning. Proceedings of the National Academy of Sciences of the United States of America
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