Karin R. McDonald, Ph.D.

Princeton University, Princeton, NJ
"Karin McDonald"


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Virginia A. Zakian grad student 2012 Princeton
 (Proteomic investigation of protein interactions and post-translational modifications of the Pfh1 helicase and yeast telomerase holoenzymes.)
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McDonald KR, Guise AJ, Pourbozorgi-Langroudi P, et al. (2016) Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity. Plos Genetics. 12: e1006238
Lin KW, McDonald KR, Guise AJ, et al. (2015) Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length. Nature Communications. 6: 8290
McDonald KR, Sabouri N, Webb CJ, et al. (2014) The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening. Dna Repair. 24: 80-6
Sabouri N, McDonald KR, Webb CJ, et al. (2012) DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase. Genes & Development. 26: 581-93
Paeschke K, McDonald KR, Zakian VA. (2010) Telomeres: structures in need of unwinding. Febs Letters. 584: 3760-72
Liu YV, Hubbi ME, Pan F, et al. (2007) Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization. The Journal of Biological Chemistry. 282: 37064-73
Bosch-Marce M, Okuyama H, Wesley JB, et al. (2007) Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia. Circulation Research. 101: 1310-8
Baek JH, Liu YV, McDonald KR, et al. (2007) Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha. The Journal of Biological Chemistry. 282: 33358-66
Baek JH, Liu YV, McDonald KR, et al. (2007) Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha. The Journal of Biological Chemistry. 282: 23572-80
McDonald KR. (1991) New distribution records for Antechinus godmani (Thomas), a restricted rainforest endemic Memoirs - Queensland Museum. 30: 487-491
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