Maria F. Sassano, Ph.D.
Affiliations: | Pharmaceutical Sciences | University of North Carolina, Chapel Hill, Chapel Hill, NC |
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"Maria Sassano"Parents
Sign in to add mentorMichael B. Jarstfer | grad student | 2009 | UNC Chapel Hill | |
(Development of G-quadruplex stabilizers as anticancer drug therapy and selective agonists of the human oxytocin receptor as a therapeutic tool for neuropsychiatric disorders.) |
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Publications
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Serafin DS, Allyn B, Sassano MF, et al. (2018) Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages. Molecular Immunology. 106: 12-21 |
Moy SS, Teng BL, Nikolova VD, et al. (2018) Prosocial effects of an oxytocin metabolite, but not synthetic oxytocin receptor agonists, in a mouse model of autism. Neuropharmacology |
Weiss DR, Karpiak J, Huang XP, et al. (2018) Selectivity Challenges in Docking Screens for GPCR Targets and Anti-Targets. Journal of Medicinal Chemistry |
Hull-Ryde EA, Porter MA, Fowler KA, et al. (2018) Identification of Cosalane as an Inhibitor of Human and Murine CC-Chemokine Receptor 7 Signaling via a High-Throughput Screen. Slas Discovery : Advancing Life Sciences R & D. 2472555218780917 |
Manglik A, Lin H, Aryal DK, et al. (2016) Structure-based discovery of opioid analgesics with reduced side effects. Nature. 1-6 |
Billard MJ, Fitzhugh DJ, Parker JS, et al. (2016) G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis. Plos One. 11: e0152856 |
Kroeze WK, Sassano MF, Huang XP, et al. (2015) PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome. Nature Structural & Molecular Biology. 22: 362-9 |
Cero C, Vostrikov VV, Verardi R, et al. (2014) The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanism. Structure (London, England : 1993). 22: 1744-53 |
Aristotelous T, Ahn S, Shukla AK, et al. (2013) Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor. Acs Medicinal Chemistry Letters. 4: 1005-1010 |
Lemieux GA, Keiser MJ, Sassano MF, et al. (2013) In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding. Plos Biology. 11: e1001712 |