Parents

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Titia de Lange grad student 2002 Rockefeller
 (Functional analysis of the human telomeric protein TRF2.)
Stephen J. Elledge post-doc 2005-2009 Harvard Medical School (Chemistry Tree)

Children

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Supawat Thongthip grad student 2011-2017 Rockefeller (Stem Cell Tree)
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Publications

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Engel JL, Zhang X, Wu M, et al. (2024) The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance. Cell
Conti BA, Ruiz PD, Broton C, et al. (2024) RTF2 controls replication repriming and ribonucleotide excision at the replisome. Nature Communications. 15: 1943
Ruiz PD, Smogorzewska A. (2023) Temporary HMCES-DNA cross-link prevents permanent DNA damage. Cell Reports. 43: 113594
Conti BA, Ruiz PD, Broton C, et al. (2023) RTF2 controls replication repriming and ribonucleotide excision at the replisome. Biorxiv : the Preprint Server For Biology
Webster ALH, Sanders MA, Patel K, et al. (2022) Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer. Nature
Elango R, Panday A, Lach FP, et al. (2022) The structure-specific endonuclease complex SLX4-XPF regulates Tus-Ter-induced homologous recombination. Nature Structural & Molecular Biology
Caballero M, Ge T, Rebelo AR, et al. (2022) Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. Human Molecular Genetics
Yang Z, Wu XS, Wei Y, et al. (2021) Transcriptional silencing of ALDH2 confers a dependency on Fanconi anemia proteins in acute myeloid leukemia. Cancer Discovery
Giunta S, Hervé S, White RR, et al. (2021) CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy. Proceedings of the National Academy of Sciences of the United States of America. 118
Lach FP, Singh S, Rickman KA, et al. (2020) Esophageal Cancer as initial presentation of Fanconi anemia in patients with a hypomorphic FANCA variant. Cold Spring Harbor Molecular Case Studies
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