Thomas R. Cech
Affiliations: | Chemistry and Biochemistry | University of Colorado, Boulder, Boulder, CO, United States |
Area:
RNA (ribozyme) catalysisWebsite:
http://nobelprize.org/nobel_prizes/chemistry/laureates/1989/cech.htmlGoogle:
"Thomas R. Cech"Bio:
The Nobel Prize in Chemistry 1989 was awarded jointly to Sidney Altman and Thomas R. Cech "for their discovery of catalytic properties of RNA"
http://www.nasonline.org/member-directory/members/15544.html
http://cechlab.colorado.edu/
http://www.hhmi.org/research/investigators/cech_bio.html
http://www.nasonline.org/programs/awards/molecular-biology.html
https://books.google.com/books?id=KAj0AAAAMAAJ
DOI: 10.1016/0022-2836(73)90143-5
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Cross-listing: PombeTree - Chemistry Tree
Parents
Sign in to add mentor| John E. Hearst | grad student | 1975 | UC Berkeley (Chemistry Tree) | |
| (Characterization of the most rapidly renaturing sequences in the main band DNA of the mouse (Mus musculus).) | ||||
| Mary Lou Pardue | post-doc | 1978 | MIT | |
Children
Sign in to add trainee| Guowei Fang | grad student | CU Boulder (Cell Biology Tree) | |
| Daniel E. Gottschling | grad student | 1984 | CU Boulder |
| Brenda L. Bass | grad student | 1985 | CU Boulder (Chemistry Tree) |
| M K. Raghuraman | grad student | 1990 | CU Boulder (Chemistry Tree) |
| Michael A. Tanner | grad student | 1992-1997 | CU Boulder (Chemistry Tree) |
| Toru M. Nakamura | grad student | 1993-1999 | CU Boulder |
| Kara M. Juneau | grad student | 2000 | CU Boulder (PombeTree) |
| Jamie M. Sperger | grad student | 2001 | CU Boulder (PombeTree) |
| April J. Livengood | grad student | 2002 | CU Boulder (PombeTree) |
| Anita G. Seto | grad student | 2002 | CU Boulder (PombeTree) |
| Stefan Aigner | grad student | 2003 | CU Boulder (PombeTree) |
| Robert L. Gottlieb | grad student | 2003 | CU Boulder (PombeTree) |
| Chrysa M. Latrick | grad student | 2009 | CU Boulder (PombeTree) |
| Andrew B. Dalby | grad student | 2014 | CU Boulder (PombeTree) |
| Tracy M. Bryan | post-doc | Children's Medical Research Institute, New South Wales, Australia | |
| Katherine L. Friedman | post-doc | Vanderbilt | |
| Feng Guo | post-doc | CU Boulder (Chemistry Tree) | |
| Michael B. Jarstfer | post-doc | UNC Chapel Hill | |
| Ming Lei | post-doc | University of Michigan | |
| Joachim Lingner | post-doc | HHMI | |
| Carolyn M. Price | post-doc | University of Cincinnati | |
| Anna Marie Pyle | post-doc | CU Boulder (Chemistry Tree) | |
| Sarah Woodson | post-doc | Johns Hopkins (FlyTree) | |
| James R. Williamson | post-doc | 1988-1990 | CU Boulder (Chemistry Tree) |
| Daniel Herschlag | post-doc | 1989-1992 | CU Boulder (Chemistry Tree) |
| Fuyuki Ishikawa | post-doc | 1990-1992 | CU Boulder (PombeTree) |
| Joseph A. Piccirilli | post-doc | 1989-1993 | CU Boulder (Chemistry Tree) |
| Jennifer A. Doudna | post-doc | 1991-1994 | CU Boulder (Chemistry Tree) |
| Scott A. Strobel | post-doc | 1992-1995 | CU Boulder (Chemistry Tree) |
| Kevin M. Weeks | post-doc | 1992-1996 | CU Boulder (Chemistry Tree) |
| Julia Promisel Cooper | post-doc | 1993-1996 | CU Boulder |
| Philip C. Bevilacqua | post-doc | 1993-1997 | CU Boulder (Chemistry Tree) |
| Barbara L. Golden | post-doc | 1993-1998 | CU Boulder (Chemistry Tree) |
| Scott K. Silverman | post-doc | 1997-2000 | CU Boulder (Chemistry Tree) |
| John Andrew Berglund | post-doc | 2000-2001 | CU Boulder (Chemistry Tree) |
| Peter Baumann | post-doc | 1998-2002 | CU Boulder |
| David C. Zappulla | post-doc | 2002-2008 | CU Boulder |
| Derek James Taylor | post-doc | 2008-2009 | CU Boulder (Chemistry Tree) |
| Andrea J. Berman | post-doc | 2007-2012 | CU Boulder (Chemistry Tree) |
| Jacob Schwartz | post-doc | 2010-2014 | CU Boulder (Chemistry Tree) |
| Chen Davidovich | post-doc | 2010-2015 | CU Boulder (Chemistry Tree) |
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Publications
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| Forino NM, Woo JZ, Zaug AJ, et al. (2023) Dissecting telomerase RNA structural heterogeneity in living human cells with DMS-MaPseq. Biorxiv : the Preprint Server For Biology |
| Song J, Gooding AR, Hemphill WO, et al. (2023) Structural basis for inactivation of PRC2 by G-quadruplex RNA. Science (New York, N.Y.). 381: 1331-1337 |
| Long Y, Hwang T, Gooding AR, et al. (2023) Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells. Biorxiv : the Preprint Server For Biology |
| Hemphill WO, Voong CK, Fenske R, et al. (2023) Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220537120 |
| Hemphill WO, Fenske R, Gooding AR, et al. (2023) PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220528120 |
| Song J, Gooding AR, Hemphill WO, et al. (2023) Structural basis for inactivation of PRC2 by G-quadruplex RNA. Biorxiv : the Preprint Server For Biology |
| Jansson-Fritzberg LI, Sousa CI, Smallegan MJ, et al. (2022) DNMT1 inhibition by pUG-fold quadruplex RNA. Rna (New York, N.Y.) |
| Zaug AJ, Goodrich KJ, Song JJ, et al. (2022) Reconstitution of a telomeric replicon organized by CST. Nature. 608: 819-825 |
| Cech TR. (2022) RNA in biological condensates. Rna (New York, N.Y.). 28: 1-2 |
| Zaug AJ, Lim CJ, Olson CL, et al. (2021) CST does not evict elongating telomerase but prevents initiation by ssDNA binding. Nucleic Acids Research |