Kurt W. Runge

Molecular Genetics Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States 
Telomeres, Biology of Aging
"Kurt Runge"

Ph.D. with Dr. Phillips Robbins on lipid-linked oligosaccharide/asparagine-linked protein glycosylation in budding yeast.

Postdoc with Dr. Virginia Zakian on telomere function in budding yeast.

Current pombe work is on the biology of aging and generating mutant libraries that allow the rapid identification of long-lived mutants.

Cross-listing: PombeTree


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Phillips W. Robbins grad student 1985 MIT (Chemistry Tree)
 (Yeast mutation in the glucosylation steps of the asparagine-linked glycosylation pathway)
Virginia A. Zakian post-doc Fred Hutchinson Cancer Center
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Vaurs M, Audry J, Runge KW, et al. (2022) A proto-telomere is elongated by telomerase in a shelterin-dependent manner in quiescent fission yeast cells. Nucleic Acids Research
Li Y, Molyneaux N, Zhang H, et al. (2022) A multiplexed, three-dimensional pooling and next-generation sequencing strategy for creating barcoded mutant arrays: construction of a Schizosaccharomyces pombe transposon insertion library. Nucleic Acids Research
Irie H, Yamamoto I, Tarumoto Y, et al. (2019) Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast. Plos Genetics. 15: e1008335
Rishavy MA, Hallgren KW, Zhang H, et al. (2019) Exon 2 Skipping Eliminates Gamma-Glutamyl Carboxylase Activity, Indicating a Partial Splicing Defect in a Patient with Vitamin K Clotting Factor Deficiency. Journal of Thrombosis and Haemostasis : Jth
Audry J, Wang J, Eisenstatt JR, et al. (2018) The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2). F1000research. 7: 1027
Wang J, Eisenstatt JR, Audry J, et al. (2018) A heterochromatin domain forms gradually at a new telomere and is dynamic at stable telomeres. Molecular and Cellular Biology
Wang J, Zhang H, Al Shibar M, et al. (2018) Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres. Dna Repair. 65: 26-33
Runge KW, Li Y. (2017) A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining. Current Genetics
Li Y, Wang J, Zhou G, et al. (2017) Non-Homologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe. Genetics
Liu Y, Lee IJ, Sun M, et al. (2016) Roles of the novel coiled-coil protein Rng10 in septum formation during fission yeast cytokinesis. Molecular Biology of the Cell
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