Michael McEachern

Affiliations: 
Genetics University of Georgia, Athens, Athens, GA, United States 
Website:
http://www.genetics.uga.edu/people_bio_mceachern.html
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"Michael McEachern"
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Publications

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Xu J, McEachern MJ. (2012) Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scrambling. Plos Genetics. 8: e1003017
Xu J, McEachern MJ. (2012) Maintenance of very long telomeres by recombination in the Kluyveromyces lactis stn1-M1 mutant involves extreme telomeric turnover, telomeric circles, and concerted telomeric amplification. Molecular and Cellular Biology. 32: 2992-3008
Hsu M, Yu EY, Sprušanský O, et al. (2012) Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance. Eukaryotic Cell. 11: 932-42
Basenko E, Topcu Z, McEachern MJ. (2011) Recombination can either help maintain very short telomeres or generate longer telomeres in yeast cells with weak telomerase activity. Eukaryotic Cell. 10: 1131-42
Guo L, Zhang D, Wang Y, et al. (2011) TRFolder: computational prediction of novel telomerase RNA structures in yeast genomes. International Journal of Bioinformatics Research and Applications. 7: 63-81
Bechard LH, Jamieson N, McEachern MJ. (2011) Recombination can cause telomere elongations as well as truncations deep within telomeres in wild-type Kluyveromyces lactis cells. Eukaryotic Cell. 10: 226-36
Basenko EY, Cesare AJ, Iyer S, et al. (2010) Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination. Nucleic Acids Research. 38: 182-9
Wang ZR, Guo L, Chen L, et al. (2009) Evidence for an additional base-pairing element between the telomeric repeat and the telomerase RNA template in Kluyveromyces lactis and other yeasts. Molecular and Cellular Biology. 29: 5389-98
Bechard LH, Butuner BD, Peterson GJ, et al. (2009) Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype. Molecular and Cellular Biology. 29: 626-39
Cesare AJ, Groff-Vindman C, Compton SA, et al. (2008) Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain. Molecular and Cellular Biology. 28: 20-9
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