Titia de Lange
Affiliations: | Rockefeller University, New York, NY, United States |
Website:
https://www.rockefeller.edu/our-scientists/heads-of-laboratories/871-titia-de-lange/Google:
"Titia de Lange"Bio:
https://www.knaw.nl/nl/leden/correspondenten/5115
https://www.knaw.nl/en/awards/laureates/dr-h-p-heinekenprijs-voor-biochemie-en-biofysica/titia-de-lange-1955
T. de Lange at the Album Academicum of the University of Amsterdam
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Piet Borst | grad student | 1985 | Amsterdam (Chemistry Tree) | |
| (Activation and transcription of surface antigen genes in trypanosomes) | ||||
| Harold Elliot Varmus | post-doc | 1985-1990 | UC Berkeley (DevTree) | |
Children
Sign in to add trainee| Dirk Hockemeyer | grad student | (Cell Biology Tree) | |
| Agata M. Smogorzewska | grad student | 2002 | Rockefeller |
| Dominique Broccoli | post-doc | (Cell Biology Tree) | |
| Jan Karlseder | post-doc | Salk Institute | |
| Susan Smith | post-doc | NYU School of Medicine | |
| Xu-Dong Zhu | post-doc | McMaster University | |
| Eros Lazzerini Denchi | post-doc | 2004-2009 | Rockefeller |
BETA: Related publications
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Publications
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| Stuart A, de Lange T. (2024) Replicative senescence is ATM driven, reversible, and accelerated by hyperactivation of ATM at normoxia. Biorxiv : the Preprint Server For Biology |
| Cai SW, Takai H, Zaug AJ, et al. (2024) POT1 recruits and regulates CST-Polα/primase at human telomeres. Cell |
| Takai H, Aria V, Borges P, et al. (2024) CST-polymerase α-primase solves a second telomere end-replication problem. Nature |
| Sonmez C, Toia B, Eickhoff P, et al. (2024) DNA-PK controls Apollo's access to leading-end telomeres. Nucleic Acids Research |
| Kinzig CG, Zakusilo G, Takai KK, et al. (2024) ATR blocks telomerase from converting DNA breaks into telomeres. Science (New York, N.Y.). 383: 763-770 |
| Takai H, Aria V, Borges P, et al. (2023) CST-Polymeraseα-primase solves a second telomere end-replication problem. Biorxiv : the Preprint Server For Biology |
| Myler LR, Toia B, Vaughan CK, et al. (2023) DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres. Nature Structural & Molecular Biology |
| Cai SW, de Lange T. (2023) CST-Polα/Primase: the second telomere maintenance machine. Genes & Development. 37: 555-569 |
| Cai SW, Takai H, Walz T, et al. (2023) Structural basis of CST-Polα/Primase recruitment and regulation by POT1 at telomeres. Biorxiv : the Preprint Server For Biology |
| Yang Z, Sharma K, de Lange T. (2022) TRF1 uses a noncanonical function of TFIIH to promote telomere replication. Genes & Development |