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David C. Zappulla

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
telomerase, telomeres, silencing, dna replication, yeast, RNA, RNP, ncRNA
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"David Zappulla"

Children

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Sean Li Gao grad student 2012 Johns Hopkins
Erin Gunter-Kirkby grad student 2012 Johns Hopkins
Kevin J. Lebo grad student 2015 Johns Hopkins
Karen E. McMurdie grad student 2016 Johns Hopkins
Melissa A. Mefford grad student 2016 Johns Hopkins (Chemistry Tree)
Rachel O. Niederer grad student 2016 Johns Hopkins
Evan P. Hass grad student 2017 Johns Hopkins
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Publications

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Chen H, Xue J, Churikov D, et al. (2017) Structural Insights into Yeast Telomerase Recruitment to Telomeres. Cell
Niederer RO, Hass EP, Zappulla DC. (2017) Long Noncoding RNAs in the Yeast S. cerevisiae. Advances in Experimental Medicine and Biology. 1008: 119-132
Niederer RO, Papadopoulos N, Zappulla DC. (2016) Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq. Scientific Reports. 6: 19376
Mefford MA, Zappulla DC. (2015) Physical connectivity mapping by circular permutation of human telomerase RNA reveals new regions critical for activity and processivity. Molecular and Cellular Biology
Hass EP, Zappulla DC. (2015) The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae. Elife. 4
Niederer RO, Zappulla DC. (2015) Refined secondary-structure models of the core of yeast and human telomerase RNAs directed by SHAPE. Rna (New York, N.Y.). 21: 1053
Lebo KJ, Niederer RO, Zappulla DC. (2015) A second essential function of the Est1-binding arm of yeast telomerase RNA. Rna (New York, N.Y.). 21: 862-76
Niederer RO, Zappulla DC. (2015) Refined secondary-structure models of the core of yeast and human telomerase RNAs directed by SHAPE. Rna (New York, N.Y.). 21: 254-61
Mefford MA, Rafiq Q, Zappulla DC. (2013) RNA connectivity requirements between conserved elements in the core of the yeast telomerase RNP. The Embo Journal. 32: 2980-93
Lebo KJ, Zappulla DC. (2012) Stiffened yeast telomerase RNA supports RNP function in vitro and in vivo. Rna (New York, N.Y.). 18: 1666-78
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