Lu Chen, Ph.D.

2021- Fox Chase Cancer Center, Philadelphia 
telomere and telomerase, RNA biology, aging
Cross-listing: Cell Biology Tree


Sign in to add mentor
Joan W. Conaway grad student 2008-2013 University of Kansas Medical Center (Cell Biology Tree)
Steven E. Artandi post-doc 2013-2021 Stanford


Sign in to add trainee
Julia Hoopman grad student 2023- Fox Chase Cancer Center, Philadelphia (Cell Biology Tree)
Alexander Morris grad student 2023- Fox Chase Cancer Center, Philadelphia (Cell Biology Tree)
Musinu Zakari post-doc 2022- Fox Chase Cancer Center, Philadelphia (Cell Biology Tree)
Aldana Vistarop post-doc 2023- Fox Chase Cancer Center, Philadelphia (Cell Biology Tree)
Soon-keat Ooi post-doc 2021-2022 Fox Chase Cancer Center, Philadelphia (Cell Biology Tree)


Sign in to add collaborator
Ylli Doksani collaborator 2022- IFOM -FIRC Institute of Molecular Oncology (Cell Biology Tree)
BETA: Related publications


You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Huda A, Arakawa H, Mazzucco G, et al. (2023) The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats. Science Advances. 9: eadf2011
Liu Y, Liu JE, Chen S, et al. (2022) Effectiveness of Nonpharmacologic Interventions for Chemotherapy-Related Cognitive Impairment in Breast Cancer Patients: A Systematic Review and Network Meta-analysis. Cancer Nursing. 46: E305-E319
Chen L, Roake CM, Maccallini P, et al. (2022) TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration. Nucleic Acids Research
Galati A, Scatolini L, Micheli E, et al. (2021) The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening. Febs Letters
Chen L, Chang HY, Artandi SE. (2021) Analysis of RNA conformation in endogenously assembled RNPs by icSHAPE. Star Protocols. 2: 100477
Vaidyanathan S, Baik R, Chen L, et al. (2021) Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus. Molecular Therapy : the Journal of the American Society of Gene Therapy
Chen L, Bellone RR, Wang Y, et al. (2020) A novel DDB2 mutation causes defective recognition of UV-induced DNA damages and prevalent equine squamous cell carcinoma. Dna Repair. 97: 103022
Chen L, Roake CM, Galati A, et al. (2020) Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation. Cell Reports. 30: 1358-1372.e5
Roake CM, Chen L, Chakravarthy AL, et al. (2019) Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease. Molecular Cell
Chen L, Roake CM, Freund A, et al. (2018) An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1. Cell
See more...