David M. Feldser, Ph.D. - Publications

Johns Hopkins University, Baltimore, MD 
Telomeres and telomerase in chromosome maintenance and stability

21/30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Robles-Oteiza C, Taylor S, Yates T, Cicchini M, Lauderback B, Cashman CR, Burds AA, Winslow MM, Jacks T, Feldser DM. Recombinase-based conditional and reversible gene regulation via XTR alleles. Nature Communications. 6: 8783. PMID 26537451 DOI: 10.1038/ncomms9783  0.92
2015 Li Y, Park AI, Mou H, Colpan C, Bizhanova A, Akama-Garren E, Joshi N, Hendrickson EA, Feldser D, Yin H, Anderson DG, Jacks T, Weng Z, Xue W. A versatile reporter system for CRISPR-mediated chromosomal rearrangements. Genome Biology. 16: 111. PMID 26018130 DOI: 10.1186/s13059-015-0680-7  0.92
2014 Chiou SH, Kim-Kiselak C, Risca VI, Heimann MK, Chuang CH, Burds AA, Greenleaf WJ, Jacks TE, Feldser DM, Winslow MM. A conditional system to specifically link disruption of protein-coding function with reporter expression in mice. Cell Reports. 7: 2078-86. PMID 24931605 DOI: 10.1016/j.celrep.2014.05.031  0.92
2011 Xue W, Meylan E, Oliver TG, Feldser DM, Winslow MM, Bronson R, Jacks T. Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. Cancer Discovery. 1: 236-47. PMID 21874163 DOI: 10.1158/2159-8290.CD-11-0073  0.92
2011 Winslow MM, Dayton TL, Verhaak RG, Kim-Kiselak C, Snyder EL, Feldser DM, Hubbard DD, DuPage MJ, Whittaker CA, Hoersch S, Yoon S, Crowley D, Bronson RT, Chiang DY, Meyerson M, et al. Suppression of lung adenocarcinoma progression by Nkx2-1. Nature. 473: 101-4. PMID 21471965 DOI: 10.1038/nature09881  0.92
2010 Feldser DM, Kostova KK, Winslow MM, Taylor SE, Cashman C, Whittaker CA, Sanchez-Rivera FJ, Resnick R, Bronson R, Hemann MT, Jacks T. Stage-specific sensitivity to p53 restoration during lung cancer progression. Nature. 468: 572-5. PMID 21107428 DOI: 10.1038/nature09535  0.92
2010 Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, Khalil AM, Zuk O, Amit I, Rabani M, Attardi LD, Regev A, Lander ES, Jacks T, Rinn JL. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 142: 409-19. PMID 20673990 DOI: 10.1016/j.cell.2010.06.040  0.92
2009 Meylan E, Dooley AL, Feldser DM, Shen L, Turk E, Ouyang C, Jacks T. Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature. 462: 104-7. PMID 19847165 DOI: 10.1038/nature08462  0.92
2009 Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature. 458: 223-7. PMID 19182780 DOI: 10.1038/nature07672  0.92
2008 Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA. Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 134: 62-73. PMID 18614011 DOI: 10.1016/j.cell.2008.06.006  0.92
2007 Feldser DM, Greider CW. Short telomeres limit tumor progression in vivo by inducing senescence. Cancer Cell. 11: 461-9. PMID 17433785 DOI: 10.1016/j.ccr.2007.02.026  0.92
2006 Feldser D, Strong MA, Greider CW. Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres. Proceedings of the National Academy of Sciences of the United States of America. 103: 2249-51. PMID 16467146 DOI: 10.1073/pnas.0511143103  0.92
2005 Hao LY, Armanios M, Strong MA, Karim B, Feldser DM, Huso D, Greider CW. Short telomeres, even in the presence of telomerase, limit tissue renewal capacity. Cell. 123: 1121-31. PMID 16360040 DOI: 10.1016/j.cell.2005.11.020  0.92
2003 Feldser DM, Hackett JA, Greider CW. Telomere dysfunction and the initiation of genome instability. Nature Reviews. Cancer. 3: 623-7. PMID 12894250 DOI: 10.1038/nrc1142  0.92
2003 Krishnamachary B, Berg-Dixon S, Kelly B, Agani F, Feldser D, Ferreira G, Iyer N, LaRusch J, Pak B, Taghavi P, Semenza GL. Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1. Cancer Research. 63: 1138-43. PMID 12615733  0.92
2001 Semenza GL, Artemov D, Bedi A, Bhujwalla Z, Chiles K, Feldser D, Laughner E, Ravi R, Simons J, Taghavi P, Zhong H. 'The metabolism of tumours': 70 years later Novartis Foundation Symposium. 240: 251-260. PMID 11727934  0.92
2001 Feldser DM, Kern SE. Oncogenic levels of mitogen-activated protein kinase (MAPK) signaling of the dinucleotide KRAS2 mutations G12F and GG12-13VC. Human Mutation. 18: 357. PMID 11668624 DOI: 10.1002/humu.1202  0.92
2001 Hackett JA, Feldser DM, Greider CW. Telomere dysfunction increases mutation rate and genomic instability. Cell. 106: 275-86. PMID 11509177 DOI: 10.1016/S0092-8674(01)00457-3  0.92
2000 Semenza GL, Agani F, Feldser D, Iyer N, Kotch L, Laughner E, Yu A. Hypoxia, HIF-1, and the pathophysiology of common human diseases Advances in Experimental Medicine and Biology. 475: 123-130. PMID 10849654  0.92
2000 Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Research. 60: 1541-5. PMID 10749120  0.92
1999 Feldser D, Agani F, Iyer NV, Pak B, Ferreira G, Semenza GL. Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2. Cancer Research. 59: 3915-8. PMID 10463582  0.92
Low-probability matches
2020 Lin JH, Huffman AP, Wattenberg MM, Walter DM, Carpenter EL, Feldser DM, Beatty GL, Furth EE, Vonderheide RH. Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis. The Journal of Experimental Medicine. 217. PMID 32453421 DOI: 10.1084/jem.20190673  0.01
2020 Tsang T, Posimo JM, Gudiel AA, Cicchini M, Feldser DM, Brady DC. Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma. Nature Cell Biology. PMID 32203415 DOI: 10.1038/s41556-020-0481-4  0.01
2020 Kharbanda A, Walter DM, Gudiel AA, Schek N, Feldser DM, Witze ES. Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis. Science Signaling. 13. PMID 32127496 DOI: 10.1126/scisignal.aax2364  0.01
2019 Walter DM, Yates TJ, Ruiz-Torres M, Kim-Kiselak C, Gudiel AA, Deshpande C, Wang WZ, Cicchini M, Stokes KL, Tobias JW, Buza E, Feldser DM. RB constrains lineage fidelity and multiple stages of tumour progression and metastasis. Nature. PMID 31043741 DOI: 10.1038/s41586-019-1172-9  0.01
2019 Stokes KL, Cortez-Retamozo V, Acosta J, Lauderback B, Robles-Oteiza C, Cicchini M, Pittet MJ, Feldser DM. Natural killer cells limit the clearance of senescent lung adenocarcinoma cells. Oncogenesis. 8: 24. PMID 30936429 DOI: 10.1038/s41389-019-0133-3  0.01
2018 Acosta J, Wang W, Feldser DM. Off and back-on again: a tumor suppressor's tale. Oncogene. PMID 29540833 DOI: 10.1038/s41388-018-0186-3  0.01
2017 Cicchini M, Buza EL, Sagal KM, Gudiel AA, Durham AC, Feldser DM. Context-Dependent Effects of Amplified MAPK Signaling during Lung Adenocarcinoma Initiation and Progression. Cell Reports. 18: 1958-1969. PMID 28228261 DOI: 10.1016/j.celrep.2017.01.069  0.01
2017 Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM. Systematic in vivo inactivation of chromatin regulating enzymes identifies Setd2 as a potent tumor suppressor in lung adenocarcinoma. Cancer Research. PMID 28202515 DOI: 10.1158/0008-5472.CAN-16-2159  0.01
2010 Jacks T, Feldser D, Winslow M. 14 Lung cancer progression European Journal of Cancer Supplements. 8: 5. DOI: 10.1016/S1359-6349(10)70823-5  0.01
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