Wai H. Tham, Ph.D. - Publications

Affiliations: 
Princeton University, Princeton, NJ 

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Gruszczyk J, Lim NT, Arnott A, He WQ, Nguitragool W, Roobsoong W, Mok YF, Murphy JM, Smith KR, Lee S, Bahlo M, Mueller I, Barry AE, Tham WH. Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement. Proceedings of the National Academy of Sciences of the United States of America. PMID 26715754 DOI: 10.1073/pnas.1516512113  1
2015 Hietanen J, Chim-Ong A, Chiramanewong T, Gruszczyk J, Roobsoong W, Tham WH, Sattabongkot J, Nguitragool W. Gene models, expression repertoire and immune response of Plasmodium vivax Reticulocyte Binding Proteins. Infection and Immunity. PMID 26712206 DOI: 10.1128/IAI.01117-15  1
2015 Kennedy AT, Schmidt CQ, Thompson JK, Weiss GE, Taechalertpaisarn T, Gilson PR, Barlow PN, Crabb BS, Cowman AF, Tham WH. Recruitment of Factor H as a Novel Complement Evasion Strategy for Blood-Stage Plasmodium falciparum Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26700768 DOI: 10.4049/jimmunol.1501581  1
2015 Tham WH, Lim NT, Weiss GE, Lopaticki S, Ansell BR, Bird M, Lucet I, Dorin-Semblat D, Doerig C, Gilson PR, Crabb BS, Cowman AF. Plasmodium falciparum Adhesins Play an Essential Role in Signalling and Activation of Invasion into Human Erythrocytes. Plos Pathogens. 11: e1005343. PMID 26694741 DOI: 10.1371/journal.ppat.1005343  1
2015 Lim NT, Harder MJ, Kennedy AT, Lin CS, Weir C, Cowman AF, Call MJ, Schmidt CQ, Tham WH. Characterization of Inhibitors and Monoclonal Antibodies that Modulate the Interaction between Plasmodium falciparum Adhesin PfRh4 with its Erythrocyte Receptor Complement Receptor 1. The Journal of Biological Chemistry. PMID 26324715 DOI: 10.1074/jbc.M115.657171  1
2015 Tham WH, Kennedy AT. Malaria: a master lock for deadly parasites. Nature. 522: 158-9. PMID 26062503 DOI: 10.1038/522158a  1
2015 Schmidt CQ, Kennedy AT, Tham WH. More than just immune evasion: Hijacking complement by Plasmodium falciparum. Molecular Immunology. 67: 71-84. PMID 25816986 DOI: 10.1016/j.molimm.2015.03.006  1
2014 Park HJ, Guariento M, Maciejewski M, Hauhart R, Tham WH, Cowman AF, Schmidt CQ, Mertens HD, Liszewski MK, Hourcade DE, Barlow PN, Atkinson JP. Using mutagenesis and structural biology to map the binding site for the Plasmodium falciparum merozoite protein PfRh4 on the human immune adherence receptor. The Journal of Biological Chemistry. 289: 450-63. PMID 24214979 DOI: 10.1074/jbc.M113.520346  1
2012 Reiling L, Richards JS, Fowkes FJ, Wilson DW, Chokejindachai W, Barry AE, Tham WH, Stubbs J, Langer C, Donelson J, Michon P, Tavul L, Crabb BS, Siba PM, Cowman AF, et al. The Plasmodium falciparum erythrocyte invasion ligand Pfrh4 as a target of functional and protective human antibodies against malaria. Plos One. 7: e45253. PMID 23028883 DOI: 10.1371/journal.pone.0045253  1
2012 Tetteh-Quarcoo PB, Schmidt CQ, Tham WH, Hauhart R, Mertens HD, Rowe A, Atkinson JP, Cowman AF, Rowe JA, Barlow PN. Lack of evidence from studies of soluble protein fragments that Knops blood group polymorphisms in complement receptor-type 1 are driven by malaria. Plos One. 7: e34820. PMID 22506052 DOI: 10.1371/journal.pone.0034820  1
2012 Tham WH, Healer J, Cowman AF. Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparum. Trends in Parasitology. 28: 23-30. PMID 22178537 DOI: 10.1016/j.pt.2011.10.002  1
2011 Chen L, Lopaticki S, Riglar DT, Dekiwadia C, Uboldi AD, Tham WH, O'Neill MT, Richard D, Baum J, Ralph SA, Cowman AF. An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum. Plos Pathogens. 7: e1002199. PMID 21909261 DOI: 10.1371/journal.ppat.1002199  1
2011 Tham WH, Schmidt CQ, Hauhart RE, Guariento M, Tetteh-Quarcoo PB, Lopaticki S, Atkinson JP, Barlow PN, Cowman AF. Plasmodium falciparum uses a key functional site in complement receptor type-1 for invasion of human erythrocytes. Blood. 118: 1923-33. PMID 21685372 DOI: 10.1182/blood-2011-03-341305  1
2011 Lopaticki S, Maier AG, Thompson J, Wilson DW, Tham WH, Triglia T, Gout A, Speed TP, Beeson JG, Healer J, Cowman AF. Reticulocyte and erythrocyte binding-like proteins function cooperatively in invasion of human erythrocytes by malaria parasites. Infection and Immunity. 79: 1107-17. PMID 21149582 DOI: 10.1128/IAI.01021-10  1
2010 Tham WH, Wilson DW, Lopaticki S, Schmidt CQ, Tetteh-Quarcoo PB, Barlow PN, Richard D, Corbin JE, Beeson JG, Cowman AF. Complement receptor 1 is the host erythrocyte receptor for Plasmodium falciparum PfRh4 invasion ligand. Proceedings of the National Academy of Sciences of the United States of America. 107: 17327-32. PMID 20855594 DOI: 10.1073/pnas.1008151107  1
2009 Triglia T, Tham WH, Hodder A, Cowman AF. Reticulocyte binding protein homologues are key adhesins during erythrocyte invasion by Plasmodium falciparum. Cellular Microbiology. 11: 1671-87. PMID 19614665 DOI: 10.1111/j.1462-5822.2009.01358.x  1
2009 Bullen HE, Tonkin CJ, O'Donnell RA, Tham WH, Papenfuss AT, Gould S, Cowman AF, Crabb BS, Gilson PR. A novel family of Apicomplexan glideosome-associated proteins with an inner membrane-anchoring role. The Journal of Biological Chemistry. 284: 25353-63. PMID 19561073 DOI: 10.1074/jbc.M109.036772  1
2009 Tham WH, Wilson DW, Reiling L, Chen L, Beeson JG, Cowman AF. Antibodies to reticulocyte binding protein-like homologue 4 inhibit invasion of Plasmodium falciparum into human erythrocytes. Infection and Immunity. 77: 2427-35. PMID 19307208 DOI: 10.1128/IAI.00048-09  1
2008 Gould SB, Tham WH, Cowman AF, McFadden GI, Waller RF. Alveolins, a new family of cortical proteins that define the protist infrakingdom Alveolata. Molecular Biology and Evolution. 25: 1219-30. PMID 18359944 DOI: 10.1093/molbev/msn070  1
2007 Elliott SR, Payne PD, Duffy MF, Byrne TJ, Tham WH, Rogerson SJ, Brown GV, Eisen DP. Antibody recognition of heterologous variant surface antigens after a single Plasmodium falciparum infection in previously naive adults. The American Journal of Tropical Medicine and Hygiene. 76: 860-4. PMID 17488905  1
2007 Duffy MF, Tham WH. Transcription and coregulation of multigene families in Plasmodium falciparum. Trends in Parasitology. 23: 183-6; discussion 18. PMID 17350338 DOI: 10.1016/j.pt.2007.02.010  1
2007 Tham WH, Payne PD, Brown GV, Rogerson SJ. Identification of basic transcriptional elements required for rif gene transcription. International Journal For Parasitology. 37: 605-15. PMID 17196595 DOI: 10.1016/j.ijpara.2006.11.006  1
2005 Hochwagen A, Tham WH, Brar GA, Amon A. The FK506 binding protein Fpr3 counteracts protein phosphatase 1 to maintain meiotic recombination checkpoint activity. Cell. 122: 861-73. PMID 16179256 DOI: 10.1016/j.cell.2005.07.010  1
2004 Marston AL, Tham WH, Shah H, Amon A. A genome-wide screen identifies genes required for centromeric cohesion. Science (New York, N.Y.). 303: 1367-70. PMID 14752166 DOI: 10.1126/science.1094220  1
2002 Tham WH, Zakian VA. Transcriptional silencing at Saccharomyces telomeres: implications for other organisms. Oncogene. 21: 512-21. PMID 11850776 DOI: 10.1038/sj.onc.1205078  1
2001 Tham WH, Wyithe JS, Ko Ferrigno P, Silver PA, Zakian VA. Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions. Molecular Cell. 8: 189-99. PMID 11511372 DOI: 10.1016/S1097-2765(01)00287-8  1
2000 Tham WH, Zakian VA. Telomeric tethers. Nature. 403: 34-5. PMID 10638738 DOI: 10.1038/47385  1
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