Wai H. Tham, Ph.D. - Publications

Princeton University, Princeton, NJ 

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Longley RJ, White MT, Takashima E, Brewster J, Morita M, Harbers M, Obadia T, Robinson LJ, Matsuura F, Liu ZSJ, Li-Wai-Suen CSN, Tham WH, Healer J, Huon C, Chitnis CE, et al. Development and validation of serological markers for detecting recent Plasmodium vivax infection. Nature Medicine. 26: 741-749. PMID 32405064 DOI: 10.1038/S41591-020-0841-4  0.368
2020 Favuzza P, de Lera Ruiz M, Thompson JK, Triglia T, Ngo A, Steel RWJ, Vavrek M, Christensen J, Healer J, Boyce C, Guo Z, Hu M, Khan T, Murgolo N, Zhao L, ... ... Tham WH, et al. Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle. Cell Host & Microbe. PMID 32109369 DOI: 10.1016/J.Chom.2020.02.005  0.391
2019 Kurtovic L, Boyle MJ, Opi DH, Kennedy AT, Tham WH, Reiling L, Chan JA, Beeson JG. Complement in malaria immunity and vaccines. Immunological Reviews. PMID 31556468 DOI: 10.1111/Imr.12802  0.386
2019 Chan LJ, Dietrich MH, Nguitragool W, Tham WH. Plasmodium vivax Reticulocyte Binding Proteins for invasion into reticulocytes. Cellular Microbiology. e13110. PMID 31469946 DOI: 10.1111/Cmi.13110  0.471
2019 He WQ, Karl S, White MT, Nguitragool W, Monteiro W, Kuehn A, Gruszczyk J, França CT, Sattabongkot J, Lacerda MVG, Tham WH, Mueller I. Antibodies to Plasmodium vivax reticulocyte binding protein 2b are associated with protection against P. vivax malaria in populations living in low malaria transmission regions of Brazil and Thailand. Plos Neglected Tropical Diseases. 13: e0007596. PMID 31425514 DOI: 10.1371/Journal.Pntd.0007596  0.458
2019 Prajapati SK, Borlon C, Rovira-Vallbona E, Gruszczyk J, Menant S, Tham WH, Kattenberg JH, Villasis E, De Meulenaere K, Gamboa D, Vinetz J, Fujita R, Xuan XN, Urbano Ferreira M, Niño CH, et al. Complement Receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes. Scientific Reports. 9: 8943. PMID 31221984 DOI: 10.1038/S41598-019-45228-6  0.402
2019 Healer J, Wong W, Thompson JK, He W, Birkinshaw RW, Miura K, Long CA, Soroka V, Søgaard TMM, Jørgensen T, de Jongh WA, Weir C, Svahn E, Czabotar PE, Tham WH, et al. Neutralizing antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes. Cellular Microbiology. e13030. PMID 30965383 DOI: 10.1111/Cmi.13030  0.395
2019 He WQ, Shakri AR, Bhardwaj R, França CT, Stanisic DI, Healer J, Kiniboro B, Robinson LJ, Guillotte-Blisnick M, Huon C, Siba P, Cowman A, King CL, Tham WH, Chitnis CE, et al. Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria. Plos Neglected Tropical Diseases. 13: e0006987. PMID 30768655 DOI: 10.1371/Journal.Pntd.0006987  0.41
2018 Gilson PR, Nguyen W, Poole WA, Teixeira JE, Thompson JK, Guo K, Stewart RJ, Ashton TD, White KL, Sanz LM, Gamo FJ, Charman SA, Wittlin S, Duffy J, Tonkin CJ, ... Tham WH, et al. Evaluation of 4-amino 2-anilinoquinazolines against and other apicomplexan parasites and in a humanized NOD- IL2Rγ mouse model of malaria. Antimicrobial Agents and Chemotherapy. PMID 30559138 DOI: 10.1128/Aac.01804-18  0.346
2018 Loy DE, Plenderleith LJ, Sundararaman SA, Liu W, Gruszczyk J, Chen YJ, Trimboli S, Learn GH, MacLean OA, Morgan ALK, Li Y, Avitto AN, Giles J, Calvignac-Spencer S, Sachse A, ... ... Tham WH, et al. Evolutionary history of human revealed by genome-wide analyses of related ape parasites. Proceedings of the National Academy of Sciences of the United States of America. PMID 30127015 DOI: 10.1073/Pnas.1810053115  0.384
2018 Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH. Cryo-EM structure of an essential Plasmodium vivax invasion complex. Nature. PMID 29950717 DOI: 10.1038/S41586-018-0249-1  0.467
2018 Gruszczyk J, Kanjee U, Chan LJ, Menant S, Malleret B, Lim NTY, Schmidt CQ, Mok YF, Lin KM, Pearson RD, Rangel G, Smith BJ, Call MJ, Weekes MP, Griffin MDW, ... ... Tham WH, et al. Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax. Science (New York, N.Y.). 359: 48-55. PMID 29302006 DOI: 10.1126/Science.Aan1078  0.426
2018 Wong W, Huang R, Menant S, Hong C, Sandow JJ, Birkinshaw RW, Healer J, Hodder AN, Kanjee U, Tonkin CJ, Heckmann D, Soroka V, Søgaard TMM, Jørgensen T, Duraisingh MT, ... ... Tham W, et al. Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex. Nature. 565: 118-121. DOI: 10.2210/Pdb6Mpv/Pdb  0.411
2017 França CT, White MT, He WQ, Hostetler JB, Brewster J, Frato G, Malhotra I, Gruszczyk J, Huon C, Lin E, Kiniboro B, Yadava A, Siba P, Galinski MR, Healer J, ... ... Tham WH, et al. Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development. Elife. 6. PMID 28949293 DOI: 10.7554/Elife.28673  0.359
2017 Cowman AF, Tonkin CJ, Tham WH, Duraisingh MT. The Molecular Basis of Erythrocyte Invasion by Malaria Parasites. Cell Host & Microbe. 22: 232-245. PMID 28799908 DOI: 10.1016/J.Chom.2017.07.003  0.4
2017 Kennedy AT, Wijeyewickrema LC, Huglo A, Lin C, Pike R, Cowman AF, Tham WH. Recruitment of Human C1 Esterase Inhibitor Controls Complement Activation on Blood Stage Plasmodium falciparum Merozoites. Journal of Immunology (Baltimore, Md. : 1950). PMID 28484054 DOI: 10.4049/Jimmunol.1700067  0.39
2017 Longley RJ, França CT, White MT, Kumpitak C, Sa-Angchai P, Gruszczyk J, Hostetler JB, Yadava A, King CL, Fairhurst RM, Rayner JC, Tham WH, Nguitragool W, Sattabongkot J, Mueller I. Asymptomatic Plasmodium vivax infections induce robust IgG responses to multiple blood-stage proteins in a low-transmission region of western Thailand. Malaria Journal. 16: 178. PMID 28454546 DOI: 10.1186/S12936-017-1826-8  0.421
2017 Sisquella X, Nebl T, Thompson JK, Whitehead L, Malpede BM, Salinas ND, Rogers K, Tolia NH, Fleig A, O'Neill J, Tham WH, Horgen FD, Cowman AF. P. falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion. Elife. 6. PMID 28226242 DOI: 10.7554/Elife.21083  0.45
2017 França CT, White MT, He W, Hostetler JB, Brewster J, Frato G, Malhotra I, Gruszczyk J, Huon C, Lin E, Kiniboro B, Yadava A, Siba P, Galinski MR, Healer J, ... ... Tham W, et al. Author response: Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development Elife. DOI: 10.7554/Elife.28673.017  0.31
2017 Sisquella X, Nebl T, Thompson JK, Whitehead L, Malpede BM, Salinas ND, Rogers K, Tolia NH, Fleig A, O’Neill J, Tham W, Horgen FD, Cowman AF. Author response: Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion Elife. DOI: 10.7554/Elife.21083.015  0.343
2016 Tham WH, Beeson JG, Rayner JC. Plasmodium vivax vaccine research - we've only just begun. International Journal For Parasitology. PMID 27899329 DOI: 10.1016/J.Ijpara.2016.09.006  0.355
2016 França CT, He WQ, Gruszczyk J, Lim NT, Lin E, Kiniboro B, Siba PM, Tham WH, Mueller I. Plasmodium vivax Reticulocyte Binding Proteins Are Key Targets of Naturally Acquired Immunity in Young Papua New Guinean Children. Plos Neglected Tropical Diseases. 10: e0005014. PMID 27677183 DOI: 10.1371/Journal.Pntd.0005014  0.459
2016 Volz JC, Yap A, Sisquella X, Thompson JK, Lim NT, Whitehead LW, Chen L, Lampe M, Tham WH, Wilson D, Nebl T, Marapana D, Triglia T, Wong W, Rogers KL, et al. Essential Role of the PfRh5/PfRipr/CyRPA Complex during Plasmodium falciparum Invasion of Erythrocytes. Cell Host & Microbe. PMID 27374406 DOI: 10.1016/J.Chom.2016.06.004  0.475
2016 Kennedy AT, Schmidt CQ, Thompson JK, Weiss GE, Taechalerpaisarn T, Gilson PR, Barlow PN, Crabb BS, Cowman AF, Tham W. Hijacking host complement regulators: Mechanisms of Plasmodium falciparum complement evasion Immunobiology. 221: 1155. DOI: 10.1016/J.Imbio.2016.06.071  0.364
2015 Gruszczyk J, Lim NT, Arnott A, He WQ, Nguitragool W, Roobsoong W, Mok YF, Murphy JM, Smith KR, Lee S, Bahlo M, Mueller I, Barry AE, Tham WH. Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement. Proceedings of the National Academy of Sciences of the United States of America. PMID 26715754 DOI: 10.1073/Pnas.1516512113  0.431
2015 Hietanen J, Chim-Ong A, Chiramanewong T, Gruszczyk J, Roobsoong W, Tham WH, Sattabongkot J, Nguitragool W. Gene models, expression repertoire and immune response of Plasmodium vivax Reticulocyte Binding Proteins. Infection and Immunity. PMID 26712206 DOI: 10.1128/Iai.01117-15  0.425
2015 Kennedy AT, Schmidt CQ, Thompson JK, Weiss GE, Taechalertpaisarn T, Gilson PR, Barlow PN, Crabb BS, Cowman AF, Tham WH. Recruitment of Factor H as a Novel Complement Evasion Strategy for Blood-Stage Plasmodium falciparum Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26700768 DOI: 10.4049/Jimmunol.1501581  0.462
2015 Tham WH, Lim NT, Weiss GE, Lopaticki S, Ansell BR, Bird M, Lucet I, Dorin-Semblat D, Doerig C, Gilson PR, Crabb BS, Cowman AF. Plasmodium falciparum Adhesins Play an Essential Role in Signalling and Activation of Invasion into Human Erythrocytes. Plos Pathogens. 11: e1005343. PMID 26694741 DOI: 10.1371/Journal.Ppat.1005343  0.478
2015 Lim NT, Harder MJ, Kennedy AT, Lin CS, Weir C, Cowman AF, Call MJ, Schmidt CQ, Tham WH. Characterization of Inhibitors and Monoclonal Antibodies that Modulate the Interaction between Plasmodium falciparum Adhesin PfRh4 with its Erythrocyte Receptor Complement Receptor 1. The Journal of Biological Chemistry. PMID 26324715 DOI: 10.1074/Jbc.M115.657171  0.447
2015 Tham WH, Kennedy AT. Malaria: a master lock for deadly parasites. Nature. 522: 158-9. PMID 26062503 DOI: 10.1038/522158A  0.392
2015 Schmidt CQ, Kennedy AT, Tham WH. More than just immune evasion: Hijacking complement by Plasmodium falciparum. Molecular Immunology. 67: 71-84. PMID 25816986 DOI: 10.1016/J.Molimm.2015.03.006  0.432
2015 Weiss GE, Gilson PR, Taechalertpaisarn T, Tham WH, de Jong NW, Harvey KL, Fowkes FJ, Barlow PN, Rayner JC, Wright GJ, Cowman AF, Crabb BS. Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes. Plos Pathogens. 11: e1004670. PMID 25723550 DOI: 10.1371/Journal.Ppat.1004670  0.405
2014 Park HJ, Guariento M, Maciejewski M, Hauhart R, Tham WH, Cowman AF, Schmidt CQ, Mertens HD, Liszewski MK, Hourcade DE, Barlow PN, Atkinson JP. Using mutagenesis and structural biology to map the binding site for the Plasmodium falciparum merozoite protein PfRh4 on the human immune adherence receptor. The Journal of Biological Chemistry. 289: 450-63. PMID 24214979 DOI: 10.1074/Jbc.M113.520346  0.42
2012 Reiling L, Richards JS, Fowkes FJ, Wilson DW, Chokejindachai W, Barry AE, Tham WH, Stubbs J, Langer C, Donelson J, Michon P, Tavul L, Crabb BS, Siba PM, Cowman AF, et al. The Plasmodium falciparum erythrocyte invasion ligand Pfrh4 as a target of functional and protective human antibodies against malaria. Plos One. 7: e45253. PMID 23028883 DOI: 10.1371/Journal.Pone.0045253  0.42
2012 Tetteh-Quarcoo PB, Schmidt CQ, Tham WH, Hauhart R, Mertens HD, Rowe A, Atkinson JP, Cowman AF, Rowe JA, Barlow PN. Lack of evidence from studies of soluble protein fragments that Knops blood group polymorphisms in complement receptor-type 1 are driven by malaria. Plos One. 7: e34820. PMID 22506052 DOI: 10.1371/Journal.Pone.0034820  0.394
2012 Tham WH, Healer J, Cowman AF. Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparum. Trends in Parasitology. 28: 23-30. PMID 22178537 DOI: 10.1016/J.Pt.2011.10.002  0.441
2011 Chen L, Lopaticki S, Riglar DT, Dekiwadia C, Uboldi AD, Tham WH, O'Neill MT, Richard D, Baum J, Ralph SA, Cowman AF. An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum. Plos Pathogens. 7: e1002199. PMID 21909261 DOI: 10.1371/Journal.Ppat.1002199  0.444
2011 Tham WH, Schmidt CQ, Hauhart RE, Guariento M, Tetteh-Quarcoo PB, Lopaticki S, Atkinson JP, Barlow PN, Cowman AF. Plasmodium falciparum uses a key functional site in complement receptor type-1 for invasion of human erythrocytes. Blood. 118: 1923-33. PMID 21685372 DOI: 10.1182/Blood-2011-03-341305  0.385
2011 Lopaticki S, Maier AG, Thompson J, Wilson DW, Tham WH, Triglia T, Gout A, Speed TP, Beeson JG, Healer J, Cowman AF. Reticulocyte and erythrocyte binding-like proteins function cooperatively in invasion of human erythrocytes by malaria parasites. Infection and Immunity. 79: 1107-17. PMID 21149582 DOI: 10.1128/Iai.01021-10  0.484
2010 Tham WH, Wilson DW, Lopaticki S, Schmidt CQ, Tetteh-Quarcoo PB, Barlow PN, Richard D, Corbin JE, Beeson JG, Cowman AF. Complement receptor 1 is the host erythrocyte receptor for Plasmodium falciparum PfRh4 invasion ligand. Proceedings of the National Academy of Sciences of the United States of America. 107: 17327-32. PMID 20855594 DOI: 10.1073/Pnas.1008151107  0.429
2009 Triglia T, Tham WH, Hodder A, Cowman AF. Reticulocyte binding protein homologues are key adhesins during erythrocyte invasion by Plasmodium falciparum. Cellular Microbiology. 11: 1671-87. PMID 19614665 DOI: 10.1111/J.1462-5822.2009.01358.X  0.458
2009 Bullen HE, Tonkin CJ, O'Donnell RA, Tham WH, Papenfuss AT, Gould S, Cowman AF, Crabb BS, Gilson PR. A novel family of Apicomplexan glideosome-associated proteins with an inner membrane-anchoring role. The Journal of Biological Chemistry. 284: 25353-63. PMID 19561073 DOI: 10.1074/Jbc.M109.036772  0.351
2009 Tham WH, Wilson DW, Reiling L, Chen L, Beeson JG, Cowman AF. Antibodies to reticulocyte binding protein-like homologue 4 inhibit invasion of Plasmodium falciparum into human erythrocytes. Infection and Immunity. 77: 2427-35. PMID 19307208 DOI: 10.1128/Iai.00048-09  0.467
2008 Gould SB, Tham WH, Cowman AF, McFadden GI, Waller RF. Alveolins, a new family of cortical proteins that define the protist infrakingdom Alveolata. Molecular Biology and Evolution. 25: 1219-30. PMID 18359944 DOI: 10.1093/Molbev/Msn070  0.337
2007 Elliott SR, Payne PD, Duffy MF, Byrne TJ, Tham WH, Rogerson SJ, Brown GV, Eisen DP. Antibody recognition of heterologous variant surface antigens after a single Plasmodium falciparum infection in previously naive adults. The American Journal of Tropical Medicine and Hygiene. 76: 860-4. PMID 17488905 DOI: 10.4269/Ajtmh.2007.76.860  0.356
2007 Duffy MF, Tham WH. Transcription and coregulation of multigene families in Plasmodium falciparum. Trends in Parasitology. 23: 183-6; discussion 18. PMID 17350338 DOI: 10.1016/J.Pt.2007.02.010  0.351
2007 Tham WH, Payne PD, Brown GV, Rogerson SJ. Identification of basic transcriptional elements required for rif gene transcription. International Journal For Parasitology. 37: 605-15. PMID 17196595 DOI: 10.1016/J.Ijpara.2006.11.006  0.335
2005 Hochwagen A, Tham WH, Brar GA, Amon A. The FK506 binding protein Fpr3 counteracts protein phosphatase 1 to maintain meiotic recombination checkpoint activity. Cell. 122: 861-73. PMID 16179256 DOI: 10.1016/J.Cell.2005.07.010  0.387
2004 Marston AL, Tham WH, Shah H, Amon A. A genome-wide screen identifies genes required for centromeric cohesion. Science (New York, N.Y.). 303: 1367-70. PMID 14752166 DOI: 10.1126/Science.1094220  0.31
2002 Tham WH, Zakian VA. Transcriptional silencing at Saccharomyces telomeres: implications for other organisms. Oncogene. 21: 512-21. PMID 11850776 DOI: 10.1038/Sj.Onc.1205078  0.534
2001 Tham WH, Wyithe JS, Ko Ferrigno P, Silver PA, Zakian VA. Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions. Molecular Cell. 8: 189-99. PMID 11511372 DOI: 10.1016/S1097-2765(01)00287-8  0.543
2000 Tham WH, Zakian VA. Telomeric tethers. Nature. 403: 34-5. PMID 10638738 DOI: 10.1038/47385  0.534
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