| Year |
Citation |
Score |
| 2018 |
Serafin DS, Allyn B, Sassano MF, Timoshchenko RG, Mattox D, Brozowski JM, Siderovski DP, Truong YK, Esserman D, Tarrant TK, Billard MJ. Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages. Molecular Immunology. 106: 12-21. PMID 30576947 DOI: 10.1016/J.Molimm.2018.12.016 |
0.349 |
|
| 2018 |
Moy SS, Teng BL, Nikolova VD, Riddick NV, Simpson CD, Van Deusen A, Janzen WP, Sassano MF, Pedersen CA, Jarstfer MB. Prosocial effects of an oxytocin metabolite, but not synthetic oxytocin receptor agonists, in a mouse model of autism. Neuropharmacology. PMID 30399367 DOI: 10.1016/J.Neuropharm.2018.10.036 |
0.528 |
|
| 2018 |
Weiss DR, Karpiak J, Huang XP, Sassano MF, Lyu J, Roth BL, Shoichet BK. Selectivity Challenges in Docking Screens for GPCR Targets and Anti-Targets. Journal of Medicinal Chemistry. PMID 29990431 DOI: 10.1021/Acs.Jmedchem.8B00718 |
0.404 |
|
| 2018 |
Hull-Ryde EA, Porter MA, Fowler KA, Kireev D, Li K, Simpson CD, Sassano MF, Suto MJ, Pearce KH, Janzen W, Coghill JM. Identification of Cosalane as an Inhibitor of Human and Murine CC-Chemokine Receptor 7 Signaling via a High-Throughput Screen. Slas Discovery : Advancing Life Sciences R & D. 2472555218780917. PMID 29958052 DOI: 10.1177/2472555218780917 |
0.316 |
|
| 2016 |
Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, Levit A, Kling RC, Bernat V, Hübner H, Huang XP, Sassano MF, Giguère PM, Löber S, Da Duan, et al. Structure-based discovery of opioid analgesics with reduced side effects. Nature. 1-6. PMID 27533032 DOI: 10.1038/Nature19112 |
0.313 |
|
| 2016 |
Billard MJ, Fitzhugh DJ, Parker JS, Brozowski JM, McGinnis MW, Timoshchenko RG, Serafin DS, Lininger R, Klauber-Demore N, Sahagian G, Truong YK, Sassano MF, Serody JS, Tarrant TK. G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis. Plos One. 11: e0152856. PMID 27049755 DOI: 10.1371/Journal.Pone.0152856 |
0.318 |
|
| 2015 |
Kroeze WK, Sassano MF, Huang XP, Lansu K, McCorvy JD, Giguère PM, Sciaky N, Roth BL. PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome. Nature Structural & Molecular Biology. 22: 362-9. PMID 25895059 DOI: 10.1038/Nsmb.3014 |
0.43 |
|
| 2014 |
Cero C, Vostrikov VV, Verardi R, Severini C, Gopinath T, Braun PD, Sassano MF, Gurney A, Roth BL, Vulchanova L, Possenti R, Veglia G, Bartolomucci A. The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanism. Structure (London, England : 1993). 22: 1744-53. PMID 25456411 DOI: 10.1016/J.Str.2014.10.001 |
0.414 |
|
| 2013 |
Aristotelous T, Ahn S, Shukla AK, Gawron S, Sassano MF, Kahsai AW, Wingler LM, Zhu X, Tripathi-Shukla P, Huang XP, Riley J, Besnard J, Read KD, Roth BL, Gilbert IH, et al. Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor. Acs Medicinal Chemistry Letters. 4: 1005-1010. PMID 24454993 DOI: 10.1021/Ml400312J |
0.437 |
|
| 2013 |
Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K. In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding. Plos Biology. 11: e1001712. PMID 24260022 DOI: 10.1371/Journal.Pbio.1001712 |
0.335 |
|
| 2013 |
Weiss DR, Ahn S, Sassano MF, Kleist A, Zhu X, Strachan R, Roth BL, Lefkowitz RJ, Shoichet BK. Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptor. Acs Chemical Biology. 8: 1018-26. PMID 23485065 DOI: 10.1021/Cb400103F |
0.465 |
|
| 2013 |
Sassano MF, Doak AK, Roth BL, Shoichet BK. Colloidal aggregation causes inhibition of G protein-coupled receptors. Journal of Medicinal Chemistry. 56: 2406-14. PMID 23437772 DOI: 10.1021/Jm301749Y |
0.388 |
|
| 2013 |
Lin H, Sassano MF, Roth BL, Shoichet BK. A pharmacological organization of G protein-coupled receptors. Nature Methods. 10: 140-6. PMID 23291723 DOI: 10.1038/Nmeth.2324 |
0.413 |
|
| 2012 |
Besnard J, Ruda GF, Setola V, Abecassis K, Rodriguiz RM, Huang XP, Norval S, Sassano MF, Shin AI, Webster LA, Simeons FR, Stojanovski L, Prat A, Seidah NG, Constam DB, et al. Automated design of ligands to polypharmacological profiles. Nature. 492: 215-20. PMID 23235874 DOI: 10.1038/Nature11691 |
0.365 |
|
| 2012 |
Sassano MF, Schlesinger AP, Jarstfer MB. Identification of G-Quadruplex Inducers Usinga Simple, Inexpensiveand Rapid High Throughput Assay, and TheirInhibition of Human Telomerase. The Open Medicinal Chemistry Journal. 6: 20-8. PMID 23173022 DOI: 10.2174/1874104501206010020 |
0.521 |
|
| 2012 |
Chen X, Sassano MF, Zheng L, Setola V, Chen M, Bai X, Frye SV, Wetsel WC, Roth BL, Jin J. Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonists. Journal of Medicinal Chemistry. 55: 7141-53. PMID 22845053 DOI: 10.1021/Jm300603Y |
0.42 |
|
| 2011 |
Chen G, Cho SJ, Huang XP, Jensen NH, Svennebring A, Sassano MF, Roth BL, Kozikowski AP. Rational Drug Design Leading to the Identification of a Potent 5-HT(2C) Agonist Lacking 5-HT(2B) Activity. Acs Medicinal Chemistry Letters. 2: 929-932. PMID 22778800 DOI: 10.1021/Ml200206Z |
0.304 |
|
| 2011 |
Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/Pnas.1104807108 |
0.357 |
|
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