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Eric N. Olson - Publications

Affiliations: 
Molecular Biology University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
muscle biology
Website:
http://www8.utsouthwestern.edu/findfac/research/0,2357,15426,00.html

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cui M, Bezprozvannaya S, Hao T, Elnwasany A, Szweda LI, Liu N, Bassel-Duby R, Olson EN. Transcription factor NFYa controls cardiomyocyte metabolism and proliferation during mouse fetal heart development. Developmental Cell. PMID 37972593 DOI: 10.1016/j.devcel.2023.10.012  0.311
2023 Dos Santos M, Shah AM, Zhang Y, Bezprozvannaya S, Chen K, Xu L, Lin W, McAnally JR, Bassel-Duby R, Liu N, Olson EN. Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution. Nature Communications. 14: 4333. PMID 37468485 DOI: 10.1038/s41467-023-40073-8  0.379
2023 Zhang Y, Ramirez-Martinez A, Chen K, McAnally JR, Cai C, Durbacz MZ, Chemello F, Wang Z, Xu L, Bassel-Duby R, Liu N, Olson EN. Net39 protects muscle nuclei from mechanical stress during the pathogenesis of Emery-Dreifuss muscular dystrophy. The Journal of Clinical Investigation. 133. PMID 37395273 DOI: 10.1172/JCI163333  0.335
2023 Shah AM, Guo L, Morales MG, Jaichander P, Chen K, Huang H, Cano Hernandez K, Xu L, Bassel-Duby R, Olson EN, Liu N. TWIST2-mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma. Science Advances. 9: eade8184. PMID 37115930 DOI: 10.1126/sciadv.ade8184  0.403
2023 Bock-Marquette I, Maar K, Maar S, Lippai B, Faskerti G, Gallyas F, Olson EN, Srivastava D. Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. International Immunopharmacology. 116: 109741. PMID 36709593 DOI: 10.1016/j.intimp.2023.109741  0.504
2022 Ramirez-Martinez A, Zhang Y, van den Boogaard MJ, McAnally JR, Rodriguez-Caycedo C, Chai AC, Chemello F, Massink MP, Cuppen I, Elferink MG, van Es RJ, Janssen NG, Walraven-van Oijen LP, Liu N, Bassel-Duby R, ... ... Olson EN, et al. Impaired activity of the fusogenic micropeptide Myomixer causes myopathy resembling Carey-Fineman-Ziter syndrome. The Journal of Clinical Investigation. 132. PMID 35642635 DOI: 10.1172/JCI159002  0.31
2022 Karri DR, Zhang Y, Chemello F, Min YL, Huang J, Kim J, Mammen PPA, Xu L, Liu N, Bassel-Duby R, Olson EN. Long-term maintenance of dystrophin expression and resistance to injury of skeletal muscle in gene edited DMD mice. Molecular Therapy. Nucleic Acids. 28: 154-167. PMID 35402069 DOI: 10.1016/j.omtn.2022.03.004  0.311
2021 Anderson DM, Anderson KM, Nelson BR, McAnally JR, Bezprozvannaya S, Shelton JM, Bassel-Duby R, Olson EN. A myocardin-adjacent lncRNA balances SRF-dependent gene transcription in the heart. Genes & Development. PMID 33985971 DOI: 10.1101/gad.348304.121  0.397
2021 Garry GA, Bezprozvannaya S, Chen K, Zhou H, Hashimoto H, Morales MG, Liu N, Bassel-Duby R, Olson EN. The histone reader PHF7 cooperates with the SWI/SNF complex at cardiac super enhancers to promote direct reprogramming. Nature Cell Biology. PMID 33941892 DOI: 10.1038/s41556-021-00668-z  0.332
2021 Ramirez-Martinez A, Zhang Y, Chen K, Kim J, Cenik BK, McAnally JR, Cai C, Shelton JM, Huang J, Brennan A, Evers BM, Mammen PPA, Xu L, Bassel-Duby R, Liu N, ... Olson EN, et al. The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization. Nature Communications. 12: 690. PMID 33514739 DOI: 10.1038/s41467-021-20987-x  0.323
2020 Chemello F, Wang Z, Li H, McAnally JR, Liu N, Bassel-Duby R, Olson EN. Degenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 33148801 DOI: 10.1073/pnas.2018391117  0.362
2020 Min YL, Chemello F, Li H, Rodriguez-Caycedo C, Sanchez-Ortiz E, Mireault AA, McAnally JR, Shelton JM, Zhang Y, Bassel-Duby R, Olson EN. Correction of Three Prominent Mutations in Mouse and Human Models of Duchenne Muscular Dystrophy by Single-Cut Genome Editing. Molecular Therapy : the Journal of the American Society of Gene Therapy. 28: 2044-2055. PMID 32892813 DOI: 10.1016/J.Ymthe.2020.05.024  0.35
2020 Wei T, Cheng Q, Min YL, Olson EN, Siegwart DJ. Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing. Nature Communications. 11: 3232. PMID 32591530 DOI: 10.1038/S41467-020-17029-3  0.31
2020 Chemello F, Bassel-Duby R, Olson EN. Correction of muscular dystrophies by CRISPR gene editing. The Journal of Clinical Investigation. 130: 2766-2776. PMID 32478678 DOI: 10.1172/Jci136873  0.346
2020 Cui M, Wang Z, Chen K, Shah AM, Tan W, Duan L, Sanchez-Ortiz E, Li H, Xu L, Liu N, Bassel-Duby R, Olson EN. Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing. Developmental Cell. PMID 32220304 DOI: 10.1016/J.Devcel.2020.02.019  0.397
2020 Zhang Y, Li H, Min YL, Sanchez-Ortiz E, Huang J, Mireault AA, Shelton JM, Kim J, Mammen PPA, Bassel-Duby R, Olson EN. Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system. Science Advances. 6: eaay6812. PMID 32128412 DOI: 10.1126/Sciadv.Aay6812  0.305
2020 Sadek H, Olson EN. Toward the Goal of Human Heart Regeneration. Cell Stem Cell. 26: 7-16. PMID 31901252 DOI: 10.1016/J.Stem.2019.12.004  0.622
2019 Amoasii L, Li H, Zhang Y, Min YL, Sanchez-Ortiz E, Shelton JM, Long C, Mireault AA, Bhattacharyya S, McAnally JR, Bassel-Duby R, Olson EN. In vivo non-invasive monitoring of dystrophin correction in a new Duchenne muscular dystrophy reporter mouse. Nature Communications. 10: 4537. PMID 31586095 DOI: 10.1038/S41467-019-12335-X  0.398
2019 Li S, Karri D, Sanchez-Ortiz E, Jaichander P, Bassel-Duby R, Liu N, Olson EN. Sema3a-Nrp1 Signaling Mediates Fast-Twitch Myofiber Specificity of Tw2 Cells. Developmental Cell. PMID 31474563 DOI: 10.1016/J.Devcel.2019.08.002  0.431
2019 Wang Z, Cui M, Shah AM, Ye W, Tan W, Min YL, Botten GA, Shelton JM, Liu N, Bassel-Duby R, Olson EN. Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling. Proceedings of the National Academy of Sciences of the United States of America. PMID 31451669 DOI: 10.1073/Pnas.1905824116  0.425
2019 Mohawk JA, Cox KH, Sato M, Yoo SH, Yanagisawa M, Olson EN, Takahashi JS. Neuronal Myocyte-specific enhancer factor 2D (MEF2D) is required for normal circadian and sleep behavior in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31420455 DOI: 10.1523/Jneurosci.0411-19.2019  0.336
2019 Amoasii L, Sanchez-Ortiz E, Fujikawa T, Elmquist JK, Bassel-Duby R, Olson EN. NURR1 activation in skeletal muscle controls systemic energy homeostasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31110021 DOI: 10.1073/Pnas.1902490116  0.359
2019 Hashimoto H, Wang Z, Garry GA, Malladi VS, Botten GA, Ye W, Zhou H, Osterwalder M, Dickel DE, Visel A, Liu N, Bassel-Duby R, Olson EN. Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers. Cell Stem Cell. PMID 31080136 DOI: 10.1016/J.Stem.2019.03.022  0.448
2019 Li S, Chen K, Zhang Y, Barnes SD, Jaichander P, Zheng Y, Hassan M, Malladi VS, Skapek SX, Xu L, Bassel-Duby R, Olson EN, Liu N. Twist2 amplification in rhabdomyosarcoma represses myogenesis and promotes oncogenesis by redirecting MyoD DNA binding. Genes & Development. PMID 30975722 DOI: 10.1101/Gad.324467.119  0.449
2019 Min YL, Li H, Rodriguez-Caycedo C, Mireault AA, Huang J, Shelton JM, McAnally JR, Amoasii L, Mammen PPA, Bassel-Duby R, Olson EN. CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells. Science Advances. 5: eaav4324. PMID 30854433 DOI: 10.1126/Sciadv.Aav4324  0.364
2019 Wang Z, Cui M, Shah A, Tan W, Liu N, Bassel-Duby R, Olson EN. Abstract 725: A Transcriptional Basis for Neonatal Heart Regeneration at Single Cell Resolution Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.725  0.379
2019 Garry GA, Hashimoto H, Wang Z, Zhou H, Liu N, Bassel-Duby R, Olson EN. Abstract 705: Synergistic Activation of the Cardiac Enhancer Landscape During Cardiac Reprogramming Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.705  0.385
2019 Shah AM, Cui M, Wang Z, Tan W, Liu N, Bassel-Duby R, Olson EN. Abstract 147: Screening for Developmental and Injury-Induced Genes That Facilitate Heart Regeneration Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.147  0.351
2019 Hashimoto H, Wang Z, Garry G, Zhou H, Bassel-Duby R, Olson EN. P2570Synergistic activation of the cardiac enhancer landscape during reprogramming European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz748.0897  0.36
2019 Singh DR, Cho E, Dalton M, Pribadi M, Makarewich CA, Olson EN, Robia SL. Oligomerization of Micropeptides that Regulate SERCA Biophysical Journal. 116: 30a-31a. DOI: 10.1016/J.Bpj.2018.11.207  0.349
2018 Cui M, Wang Z, Bassel-Duby R, Olson EN. Genetic and epigenetic regulation of cardiomyocytes in development, regeneration and disease. Development (Cambridge, England). 145. PMID 30573475 DOI: 10.1242/Dev.171983  0.448
2018 Zhang QJ, Tran TAT, Wang M, Ranek MJ, Kokkonen-Simon KM, Gao J, Luo X, Tan W, Kyrychenko V, Liao L, Xu J, Hill JA, Olson EN, Kass DA, Martinez ED, et al. Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis. Nature Communications. 9: 5230. PMID 30531796 DOI: 10.1038/S41467-018-07173-2  0.45
2018 Min YL, Bassel-Duby R, Olson EN. CRISPR Correction of Duchenne Muscular Dystrophy. Annual Review of Medicine. PMID 30379597 DOI: 10.1146/Annurev-Med-081117-010451  0.342
2018 Makarewich CA, Munir AZ, Schiattarella GG, Bezprozvannaya S, Raguimova ON, Cho EE, Vidal AH, Robia SL, Bassel-Duby R, Olson EN. The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy. Elife. 7. PMID 30299255 DOI: 10.7554/Elife.38319  0.384
2018 Amoasii L, Hildyard JCW, Li H, Sanchez-Ortiz E, Mireault A, Caballero D, Harron R, Stathopoulou TR, Massey C, Shelton JM, Bassel-Duby R, Piercy RJ, Olson EN. Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy. Science (New York, N.Y.). PMID 30166439 DOI: 10.1126/Science.Aau1549  0.426
2018 Min YL, Jaichander P, Sanchez-Ortiz E, Bezprozvannaya S, Malladi VS, Cui M, Wang Z, Bassel-Duby R, Olson EN, Liu N. Identification of a multipotent Twist2-expressing cell population in the adult heart. Proceedings of the National Academy of Sciences of the United States of America. PMID 30127033 DOI: 10.1073/Pnas.1800526115  0.383
2018 Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN. MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation. Cell Reports. 23: 3701-3709. PMID 29949755 DOI: 10.1016/J.Celrep.2018.05.058  0.336
2018 Hashimoto H, Olson EN, Bassel-Duby R. Therapeutic approaches for cardiac regeneration and repair. Nature Reviews. Cardiology. PMID 29872165 DOI: 10.1038/S41569-018-0036-6  0.36
2018 Papizan JB, Vidal AH, Bezprozvannaya S, Bassel-Duby R, Olson EN. Cullin3-RING ubiquitin ligase activity is required for striated muscle function in mice. The Journal of Biological Chemistry. PMID 29653945 DOI: 10.1074/Jbc.Ra118.002104  0.425
2018 Bi P, McAnally JR, Shelton JM, Sánchez-Ortiz E, Bassel-Duby R, Olson EN. Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581287 DOI: 10.1073/Pnas.1800052115  0.437
2018 Polster A, Nelson BR, Papadopoulos S, Olson EN, Beam KG. Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of Ca1.1. The Journal of General Physiology. PMID 29467163 DOI: 10.1085/Jgp.201711917  0.335
2018 Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, Zhang Y, Min YL, Shelton JM, Mammen PPA, Liaw NY, Zimmermann WH, Bassel-Duby R, Schneider JW, Olson EN. Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing. Science Advances. 4: eaap9004. PMID 29404407 DOI: 10.1126/Sciadv.Aap9004  0.375
2018 Makarewich CA, Munir AZ, Schiattarella GG, Bezprozvannaya S, Raguimova ON, Cho EE, Vidal AH, Robia SL, Bassel-Duby R, Olson EN. Author response: The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy Elife. DOI: 10.7554/Elife.38319.019  0.315
2018 Wang Z, Cui M, Ye W, Tan W, Botten G, McAnally J, Shelton JM, Kim MS, Malladi V, Chen B, Bassel-Duby R, Liu N, Olson EN. Abstract 347: Mechanistic Basis of Neonatal Heart Regeneration Revealed by Transcriptome and Histone Modification Profiling Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.347  0.353
2018 Zhu X, Leboeuf M, Liu F, Chen S, Olson E, Morrisey E, Dlugosz A, MIllar S. 165 HDAC1 and HDAC2 regulate homeostasis and tumorigenesis of postnatal epidermis Journal of Investigative Dermatology. 138: S28. DOI: 10.1016/J.Jid.2018.03.170  0.324
2017 Amoasii L, Long C, Li H, Mireault AA, Shelton JM, Sanchez-Ortiz E, McAnally JR, Bhattacharyya S, Schmidt F, Grimm D, Hauschka SD, Bassel-Duby R, Olson EN. Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy. Science Translational Medicine. 9. PMID 29187645 DOI: 10.1126/Scitranslmed.Aan8081  0.388
2017 Shi J, Bi P, Pei J, Li H, Grishin NV, Bassel-Duby R, Chen EH, Olson EN. Requirement of the fusogenic micropeptide myomixer for muscle formation in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078404 DOI: 10.1073/Pnas.1715229114  0.677
2017 Carroll KJ, Olson EN. Considerations for Cardiac CRISPR. Circulation Research. 121: 1111-1112. PMID 29074525 DOI: 10.1161/Circresaha.117.311974  0.361
2017 Zhou H, Morales MG, Hashimoto H, Dickson ME, Song K, Ye W, Kim MS, Niederstrasser H, Wang Z, Chen B, Posner BA, Bassel-Duby R, Olson EN. ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression. Genes & Development. 31: 1770-1783. PMID 28982760 DOI: 10.1101/Gad.305482.117  0.438
2017 Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton JM, Long C, Schneider JW, Zimmermann WH, Bassel-Duby R, Olson EN. Functional correction of dystrophin actin binding domain mutations by genome editing. Jci Insight. 2. PMID 28931764 DOI: 10.1172/Jci.Insight.95918  0.366
2017 Papizan JB, Garry GA, Brezprozvannaya S, McAnally JR, Bassel-Duby R, Liu N, Olson EN. Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice. The Journal of Clinical Investigation. PMID 28872460 DOI: 10.1172/Jci93445  0.458
2017 Ramirez-Martinez A, Cenik BK, Bezprozvannaya S, Chen B, Bassel-Duby R, Liu N, Olson E. KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination. Elife. 6. PMID 28826497 DOI: 10.7554/Elife.26439  0.41
2017 Baskin KK, Makarewich CA, DeLeon SM, Ye W, Chen B, Beetz N, Schrewe H, Bassel-Duby R, Olson EN. MED12 regulates a transcriptional network of calcium-handling genes in the heart. Jci Insight. 2. PMID 28724790 DOI: 10.1172/Jci.Insight.91920  0.466
2017 Di Gioia SA, Connors S, Matsunami N, Cannavino J, Rose MF, Gilette NM, Artoni P, de Macena Sobreira NL, Chan WM, Webb BD, Robson CD, Cheng L, Van Ryzin C, Ramirez-Martinez A, Mohassel P, ... ... Olson EN, et al. A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome. Nature Communications. 8: 16077. PMID 28681861 DOI: 10.1038/Ncomms16077  0.388
2017 Zhang Y, Long C, Li H, McAnally JR, Baskin KK, Shelton JM, Bassel-Duby R, Olson EN. CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice. Science Advances. 3: e1602814. PMID 28439558 DOI: 10.1126/Sciadv.1602814  0.353
2017 Amoasii L, Olson EN, Bassel-Duby R. Control of Muscle Metabolism by the Mediator Complex. Cold Spring Harbor Perspectives in Medicine. PMID 28432117 DOI: 10.1101/Cshperspect.A029843  0.361
2017 Bi P, Ramirez-Martinez A, Li H, Cannavino J, McAnally JR, Shelton JM, Sánchez-Ortiz E, Bassel-Duby R, Olson EN. Control of muscle formation by the fusogenic micropeptide myomixer. Science (New York, N.Y.). PMID 28386024 DOI: 10.1126/Science.Aam9361  0.417
2017 Abad M, Hashimoto H, Zhou H, Morales MG, Chen B, Bassel-Duby R, Olson EN. Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity. Stem Cell Reports. PMID 28262548 DOI: 10.1016/J.Stemcr.2017.01.025  0.483
2017 Liu N, Garry GA, Li S, Bezprozvannaya S, Sanchez-Ortiz E, Chen B, Shelton JM, Jaichander P, Bassel-Duby R, Olson EN. A Twist2-dependent progenitor cell contributes to adult skeletal muscle. Nature Cell Biology. PMID 28218909 DOI: 10.1038/Ncb3477  0.45
2017 Moon J, Zhou H, Zhang LS, Tan W, Liu Y, Zhang S, Morlock LK, Bao X, Palecek SP, Feng JQ, Williams NS, Amatruda JF, Olson EN, Bassel-Duby R, Lum L. Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist. Proceedings of the National Academy of Sciences of the United States of America. PMID 28143939 DOI: 10.1073/Pnas.1621346114  0.388
2017 Ramirez-Martinez A, Cenik BK, Bezprozvannaya S, Chen B, Bassel-Duby R, Liu N, Olson EN. Author response: KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination Elife. DOI: 10.7554/Elife.26439.024  0.364
2017 Fiore CM, McKeown MR, Lee E, Eaton ML, Smith D, Austgen K, Chen MW, Guenther M, Corces MR, Majeti R, Olson E, Fritz CC. Abstract PR05: SY-1425 (tamibarotene), a potent and selective RARα agonist, induces changes in the transcriptional regulatory circuit of AML cells leading to differentiation Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Hemmal17-Pr05  0.345
2017 Hu S, Ke N, Ren Y, Miljovska S, Rajagopal N, McKeown M, Orlando D, Sprott K, Choi YJ, Olson E, Fritz CC. Abstract 1151: SY-1365, a potent and selective CDK7 inhibitor, exhibits promising anti-tumor activity in multiple preclinical models of aggressive solid tumors Cancer Research. 77: 1151-1151. DOI: 10.1158/1538-7445.Am2017-1151  0.328
2017 Bradley M, Marineau J, Choi Y, Hamman K, Malojcic G, Orlando D, Ren Y, Ke N, Hu S, Olson E, Fritz C, Roberts C. Abstract 1143: Targeting the transcriptional kinases CDK12 and CDK13 in breast and ovarian cancer Cancer Research. 77: 1143-1143. DOI: 10.1158/1538-7445.Am2017-1143  0.311
2017 Makarewich C, Bezprozvannaya S, Bassel-Duby R, Olson E. DWORF overexpression prevents heart failure in an experimental mouse model of dilated cardiomyopathy Journal of Molecular and Cellular Cardiology. 112: 161. DOI: 10.1016/J.Yjmcc.2017.07.091  0.303
2016 Anderson DM, Makarewich CA, Anderson KM, Shelton JM, Bezprozvannaya S, Bassel-Duby R, Olson EN. Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides. Science Signaling. 9: ra119. PMID 27923914 DOI: 10.1126/Scisignal.Aaj1460  0.438
2016 Anderson KM, Anderson DM, McAnally JR, Shelton JM, Bassel-Duby R, Olson EN. Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development. Nature. PMID 27783597 DOI: 10.1038/Nature20128  0.381
2016 Long C, Amoasii L, Bassel-Duby R, Olson EN. Genome Editing of Monogenic Neuromuscular Diseases: A Systematic Review. Jama Neurology. PMID 27668807 DOI: 10.1001/Jamaneurol.2016.3388  0.332
2016 Polster A, Nelson BR, Olson EN, Beam KG. Stac3 has a direct role in skeletal muscle-type excitation-contraction coupling that is disrupted by a myopathy-causing mutation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27621462 DOI: 10.1073/Pnas.1612441113  0.306
2016 Lodka D, Pahuja A, Geers-Knörr C, Scheibe RJ, Nowak M, Hamati J, Köhncke C, Purfürst B, Kanashova T, Schmidt S, Glass DJ, Morano I, Heuser A, Kraft T, Bassel-Duby R, ... Olson EN, et al. Muscle RING-finger 2 and 3 maintain striated-muscle structure and function. Journal of Cachexia, Sarcopenia and Muscle. 7: 165-80. PMID 27493870 DOI: 10.1002/Jcsm.12057  0.413
2016 Anderson DM, Cannavino J, Li H, Anderson KM, Nelson BR, McAnally J, Bezprozvannaya S, Liu Y, Lin W, Liu N, Bassel-Duby R, Olson EN. Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106. Proceedings of the National Academy of Sciences of the United States of America. PMID 27418600 DOI: 10.1073/Pnas.1608423113  0.428
2016 Cenik BK, Liu N, Chen B, Bezprozvannaya S, Olson EN, Bassel-Duby R. Myocardin-related transcription factors are required for skeletal muscle development. Development (Cambridge, England). PMID 27385017 DOI: 10.1242/Dev.135855  0.482
2016 Lee DH, Park JO, Kim TS, Kim SK, Kim TH, Kim MC, Park GS, Kim JH, Kuninaka S, Olson EN, Saya H, Kim SY, Lee H, Lim DS. LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development. Nature Communications. 7: 11961. PMID 27358050 DOI: 10.1038/Ncomms11961  0.352
2016 Tao G, Kahr PC, Morikawa Y, Zhang M, Rahmani M, Heallen TR, Li L, Sun Z, Olson EN, Amendt BA, Martin JF. Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury. Nature. 534: 119-23. PMID 27251288 DOI: 10.1038/Nature17959  0.599
2016 Li N, Subrahmanyan L, Smith E, Yu X, Zaidi S, Choi M, Mane S, Nelson-Williams C, Bahjati M, Kazemi M, Hashemi M, Fathzadeh M, Narayanan A, Tian L, Montazeri F, ... ... Olson EN, et al. Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. American Journal of Human Genetics. PMID 27181681 DOI: 10.1016/J.Ajhg.2016.03.022  0.403
2016 Singh A, Ramesh S, Cibi DM, Yun LS, Li J, Li L, Manderfield LJ, Olson EN, Epstein JA, Singh MK. Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development. Cell Reports. PMID 27160901 DOI: 10.1016/J.Celrep.2016.04.027  0.383
2016 Karsenty G, Olson EN. Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication. Cell. 164: 1248-56. PMID 26967290 DOI: 10.1016/J.Cell.2016.02.043  0.301
2016 Amoasii L, Holland W, Sanchez-Ortiz E, Baskin KK, Pearson M, Burgess SC, Nelson BR, Bassel-Duby R, Olson EN. A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism. Genes & Development. 30: 434-46. PMID 26883362 DOI: 10.1101/Gad.273128.115  0.616
2016 Zhang L, He X, Liu L, Jiang M, Zhao C, Wang H, He D, Zheng T, Zhou X, Hassan A, Ma Z, Xin M, Sun Z, Lazar MA, Goldman SA, ... Olson EN, et al. Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch. Developmental Cell. 36: 316-330. PMID 26859354 DOI: 10.1016/J.Devcel.2016.01.002  0.354
2016 Millay DP, Gamage DG, Quinn ME, Min YL, Mitani Y, Bassel-Duby R, Olson EN. Structure-function analysis of myomaker domains required for myoblast fusion. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858401 DOI: 10.1073/Pnas.1600101113  0.424
2016 Nelson BR, Makarewich CA, Anderson DM, Winders BR, Troupes CD, Wu F, Reese AL, McAnally JR, Chen X, Kavalali ET, Cannon SC, Houser SR, Bassel-Duby R, Olson EN. A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle. Science (New York, N.Y.). 351: 271-275. PMID 26816378 DOI: 10.1126/Science.Aad4076  0.353
2016 Hanna JA, Garcia MR, Go JC, Finkelstein D, Kodali K, Pagala V, Olson EN, Peng J, Hatley ME. Abstract B05: MicroRNA-206 drives rhabdomyosarcoma differentiation through downregulation of PAX7 Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-B05  0.3
2016 Hu S, Ke N, Ren Y, Lopez J, Miljovska S, Orlando D, Schmidt D, Bradley M, Sprott K, Olson E, Fritz CC, Choi YJ. Abstract 4820: Selective CDK7 inhibitors suppress super enhancer-genes, induce massive apoptosis in acute myeloid leukemia and demonstrate durablein vivoefficacy Cancer Research. 76: 4820-4820. DOI: 10.1158/1538-7445.Am2016-4820  0.353
2016 Long C, Li H, Kyrychenko V, Zhou H, Bhattacharyya S, Rodriguez CE, Shelton JM, Mammen P, Schneider J, Bassel-Duby R, Olson EN. 730. Permanent Correction of Diverse Muscular Dystrophy Mutations in Human Cardiomyocytes by Myoediting Molecular Therapy. 24: S288. DOI: 10.1016/S1525-0016(16)33538-9  0.381
2015 Manderfield LJ, Engleka KA, Aghajanian H, Gupta M, Yang S, Li L, Baggs JE, Hogenesch JB, Olson EN, Epstein JA. Pax3 and Hippo Signaling Coordinate Melanocyte Gene Expression in Neural Crest. Cell Reports. 10: 841. PMID 30849859 DOI: 10.1016/J.Celrep.2015.01.041  0.344
2015 Long C, Amoasii L, Mireault AA, McAnally JR, Li H, Sanchez-Ortiz E, Bhattacharyya S, Shelton JM, Bassel-Duby R, Olson EN. Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy. Science (New York, N.Y.). PMID 26721683 DOI: 10.1126/Science.Aad5725  0.423
2015 Carroll KJ, Makarewich CA, McAnally J, Anderson DM, Zentilin L, Liu N, Giacca M, Bassel-Duby R, Olson EN. A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9. Proceedings of the National Academy of Sciences of the United States of America. PMID 26719419 DOI: 10.1073/Pnas.1523918113  0.421
2015 Wang J, Xiao Y, Hsu CW, Martinez-Traverso IM, Zhang M, Bai Y, Ishii M, Maxson RE, Olson EN, Dickinson ME, Wythe JD, Martin JF. Yap and Taz play a crucial role in neural crest-derived craniofacial development. Development (Cambridge, England). PMID 26718006 DOI: 10.1242/Dev.126920  0.623
2015 Mokalled MH, Carroll KJ, Cenik BK, Chen B, Liu N, Olson EN, Bassel-Duby R. Myocardin-related transcription factors are required for cardiac development and function. Developmental Biology. PMID 26386146 DOI: 10.1016/J.Ydbio.2015.09.006  0.467
2015 Zhou H, Dickson ME, Kim MS, Bassel-Duby R, Olson EN. Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 112: 11864-9. PMID 26354121 DOI: 10.1073/Pnas.1516237112  0.426
2015 Hinkel R, Ball HL, DiMaio JM, Shrivastava S, Thatcher JE, Singh AN, Sun X, Faskerti G, Olson EN, Kupatt C, Bock-Marquette I. C-terminal variable AGES domain of Thymosin β4: the molecule's primary contribution in support of post-ischemic cardiac function and repair. Journal of Molecular and Cellular Cardiology. 87: 113-25. PMID 26255251 DOI: 10.1016/J.Yjmcc.2015.07.004  0.377
2015 Manderfield LJ, Aghajanian H, Engleka KA, Lim LY, Lui F, Jain R, Li L, Olson EN, Epstein JA. Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest. Development (Cambridge, England). PMID 26253400 DOI: 10.1242/Dev.125807  0.417
2015 Weinl C, Castaneda Vega S, Riehle H, Stritt C, Calaminus C, Wolburg H, Mauel S, Breithaupt A, Gruber AD, Wasylyk B, Olson EN, Adams RH, Pichler BJ, Nordheim A. Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke. Proceedings of the National Academy of Sciences of the United States of America. 112: 9914-9. PMID 26221020 DOI: 10.1073/Pnas.1509047112  0.315
2015 Du Bois P, Pablo Tortola C, Lodka D, Kny M, Schmidt F, Song K, Schmidt S, Bassel-Duby R, Olson EN, Fielitz J. Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression. Circulation Research. 117: 424-36. PMID 26137861 DOI: 10.1161/Circresaha.114.305393  0.429
2015 Ye J, Beetz N, O'Keeffe S, Tapia JC, Macpherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T. hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function. Proceedings of the National Academy of Sciences of the United States of America. 112: E3020-9. PMID 26039991 DOI: 10.1073/Pnas.1508461112  0.4
2015 Cenik BK, Garg A, McAnally JR, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, Liu N. Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3. The Journal of Clinical Investigation. 125: 1569-78. PMID 25774500 DOI: 10.1172/Jci80115  0.471
2015 Baskin KK, Winders BR, Olson EN. Muscle as a "mediator" of systemic metabolism. Cell Metabolism. 21: 237-48. PMID 25651178 DOI: 10.1016/J.Cmet.2014.12.021  0.394
2015 Anderson DM, Anderson KM, Chang CL, Makarewich CA, Nelson BR, McAnally JR, Kasaragod P, Shelton JM, Liou J, Bassel-Duby R, Olson EN. A micropeptide encoded by a putative long noncoding RNA regulates muscle performance. Cell. 160: 595-606. PMID 25640239 DOI: 10.1016/J.Cell.2015.01.009  0.414
2015 Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV. MyoR modulates cardiac conduction by repressing Gata4. Molecular and Cellular Biology. 35: 649-61. PMID 25487574 DOI: 10.1128/Mcb.00860-14  0.464
2015 Bradley EW, Carpio LR, Olson EN, Westendorf JJ. Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification. The Journal of Biological Chemistry. 290: 118-26. PMID 25389289 DOI: 10.1074/Jbc.M114.596247  0.347
2015 Ren Y, Brown V, Hu S, Lopez J, Miljovska S, Schmidt D, Bradley M, Sprott K, Olson E, Fritz CC, Choi YJ. Targeting Transcriptional Dependency in Acute Myeloid Leukemia (AML) with a Covalent Inhibitor of Transcriptional Kinase CDK7 Blood. 126: 1354-1354. DOI: 10.1182/Blood.V126.23.1354.1354  0.333
2015 Eaton M, Corces-Zimmerman R, Lopez J, Fritz C, Olson E, Majeti R, Loven J. Abstract 2212: Super-enhancer landscapes specify molecular subtypes and novel targets in acute myeloid leukemia Cancer Research. 75: 2212-2212. DOI: 10.1158/1538-7445.Am2015-2212  0.384
2014 Manderfield LJ, Engleka KA, Aghajanian H, Gupta M, Yang S, Li L, Baggs JE, Hogenesch JB, Olson EN, Epstein JA. Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest. Cell Reports. 9: 1885-95. PMID 25466249 DOI: 10.1016/J.Celrep.2014.10.061  0.435
2014 Baskin KK, Grueter CE, Kusminski CM, Holland WL, Bookout AL, Satapati S, Kong YM, Burgess SC, Malloy CR, Scherer PE, Newgard CB, Bassel-Duby R, Olson EN. MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver. Embo Molecular Medicine. 6: 1610-21. PMID 25422356 DOI: 10.15252/Emmm.201404218  0.572
2014 Nam YJ, Lubczyk C, Bhakta M, Zang T, Fernandez-Perez A, McAnally J, Bassel-Duby R, Olson EN, Munshi NV. Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors. Development (Cambridge, England). 141: 4267-78. PMID 25344074 DOI: 10.1242/Dev.114025  0.428
2014 Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, Gallazzini M, Olson EN, Lam H, Henske EP, Dong Z, Apte U, Pallet N, Johnson RL, Terzi F, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. The Journal of Experimental Medicine. 211: 2249-63. PMID 25288394 DOI: 10.1084/Jem.20140341  0.355
2014 Kreusser MM, Lehmann LH, Keranov S, Hoting MO, Oehl U, Kohlhaas M, Reil JC, Neumann K, Schneider MD, Hill JA, Dobrev D, Maack C, Maier LS, Gröne HJ, Katus HA, ... Olson EN, et al. Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy. Circulation. 130: 1262-73. PMID 25124496 DOI: 10.1161/Circulationaha.114.006185  0.619
2014 Long C, McAnally JR, Shelton JM, Mireault AA, Bassel-Duby R, Olson EN. Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA. Science (New York, N.Y.). 345: 1184-8. PMID 25123483 DOI: 10.1126/Science.1254445  0.414
2014 Porrello ER, Olson EN. A neonatal blueprint for cardiac regeneration. Stem Cell Research. 13: 556-70. PMID 25108892 DOI: 10.1016/J.Scr.2014.06.003  0.387
2014 Millay DP, Sutherland LB, Bassel-Duby R, Olson EN. Myomaker is essential for muscle regeneration. Genes & Development. 28: 1641-6. PMID 25085416 DOI: 10.1101/Gad.247205.114  0.429
2014 Long C, Grueter CE, Song K, Qin S, Qi X, Kong YM, Shelton JM, Richardson JA, Zhang CL, Bassel-Duby R, Olson EN. Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 111: 11521-6. PMID 25049392 DOI: 10.1073/Pnas.1411251111  0.419
2014 Munshi NV, Olson EN. Translational medicine. Improving cardiac rhythm with a biological pacemaker. Science (New York, N.Y.). 345: 268-9. PMID 25035474 DOI: 10.1126/Science.1257976  0.302
2014 Papizan JB, Olson EN. Hippo in the path to heart repair. Circulation Research. 115: 332-4. PMID 25035132 DOI: 10.1161/Circresaha.114.304389  0.409
2014 Lee JH, Bassel-Duby R, Olson EN. Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 111: 9491-6. PMID 24979807 DOI: 10.1073/Pnas.1409427111  0.396
2014 Garg A, O'Rourke J, Long C, Doering J, Ravenscroft G, Bezprozvannaya S, Nelson BR, Beetz N, Li L, Chen S, Laing NG, Grange RW, Bassel-Duby R, Olson EN. KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy. The Journal of Clinical Investigation. 124: 3529-39. PMID 24960163 DOI: 10.1172/Jci74994  0.39
2014 Hinkel R, Trenkwalder T, Petersen B, Husada W, Gesenhues F, Lee S, Hannappel E, Bock-Marquette I, Theisen D, Leitner L, Boekstegers P, Cierniewski C, Müller OJ, le Noble F, Adams RH, ... ... Olson E, et al. MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2. Nature Communications. 5: 3970. PMID 24910328 DOI: 10.1038/Ncomms4970  0.426
2014 Liu N, Nelson BR, Bezprozvannaya S, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN. Requirement of MEF2A, C, and D for skeletal muscle regeneration. Proceedings of the National Academy of Sciences of the United States of America. 111: 4109-14. PMID 24591619 DOI: 10.1073/Pnas.1401732111  0.453
2014 Aurora AB, Porrello ER, Tan W, Mahmoud AI, Hill JA, Bassel-Duby R, Sadek HA, Olson EN. Macrophages are required for neonatal heart regeneration. The Journal of Clinical Investigation. 124: 1382-92. PMID 24569380 DOI: 10.1172/Jci72181  0.658
2014 Eom GH, Nam YS, Oh JG, Choe N, Min HK, Yoo EK, Kang G, Nguyen VH, Min JJ, Kim JK, Lee IK, Bassel-Duby R, Olson EN, Park WJ, Kook H. Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy. Circulation Research. 114: 1133-43. PMID 24526703 DOI: 10.1161/Circresaha.114.303429  0.362
2014 Mahmoud AI, Porrello ER, Kimura W, Olson EN, Sadek HA. Surgical models for cardiac regeneration in neonatal mice. Nature Protocols. 9: 305-11. PMID 24434799 DOI: 10.1038/Nprot.2014.021  0.641
2014 Nelson BR, Anderson DM, Olson EN. Small open reading frames pack a big punch in cardiac calcium regulation. Circulation Research. 114: 18-20. PMID 24385504 DOI: 10.1161/Circresaha.113.302716  0.338
2014 Marroncelli N, Noviello C, Consalvi S, Saccone V, Puri PL, Olson EN, Adamo S, Moresi V. HDAC4 is necessary for satellite cell differentiation and muscle regeneration Italian Journal of Anatomy and Embryology. 119: 126. DOI: 10.13128/Ijae-15965  0.455
2014 Olson EN. The molecules and mechanisms of heart development, disease and regeneration Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-O21  0.436
2014 Corces-Zimmerman MR, Eaton M, Lopez J, Ke N, Fritz C, Olson E, Majeti R, Loven J. Discovery and Characterization of Super-Enhancer-Associated Dependencies in Acute Myeloid Leukemia Blood. 124: 3539-3539. DOI: 10.1182/Blood.V124.21.3539.3539  0.378
2013 Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, Osborne GF, Wadel K, Touller C, Butler R, Robertson J, Franklin SA, Smith DL, Park L, Marks PA, ... ... Olson EN, et al. HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. Plos Biology. 11: e1001717. PMID 24302884 DOI: 10.1371/Journal.Pbio.1001717  0.314
2013 Ozcan L, Cristina de Souza J, Harari AA, Backs J, Olson EN, Tabas I. Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling. Cell Metabolism. 18: 803-15. PMID 24268736 DOI: 10.1016/J.Cmet.2013.10.011  0.548
2013 Velasquez LS, Sutherland LB, Liu Z, Grinnell F, Kamm KE, Schneider JW, Olson EN, Small EM. Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing. Proceedings of the National Academy of Sciences of the United States of America. 110: 16850-5. PMID 24082095 DOI: 10.1073/Pnas.1316764110  0.457
2013 Das A, Tanigawa S, Karner CM, Xin M, Lum L, Chen C, Olson EN, Perantoni AO, Carroll TJ. Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. Nature Cell Biology. 15: 1035-44. PMID 23974041 DOI: 10.1038/Ncb2828  0.355
2013 Johnson AN, Mokalled MH, Valera JM, Poss KD, Olson EN. Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi. Development (Cambridge, England). 140: 3645-56. PMID 23942517 DOI: 10.1242/Dev.095596  0.49
2013 Xin M, Kim Y, Sutherland LB, Murakami M, Qi X, McAnally J, Porrello ER, Mahmoud AI, Tan W, Shelton JM, Richardson JA, Sadek HA, Bassel-Duby R, Olson EN. Hippo pathway effector Yap promotes cardiac regeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: 13839-44. PMID 23918388 DOI: 10.1073/Pnas.1313192110  0.712
2013 Millay DP, O'Rourke JR, Sutherland LB, Bezprozvannaya S, Shelton JM, Bassel-Duby R, Olson EN. Myomaker is a membrane activator of myoblast fusion and muscle formation. Nature. 499: 301-5. PMID 23868259 DOI: 10.1038/Nature12343  0.419
2013 Lavado A, He Y, Paré J, Neale G, Olson EN, Giovannini M, Cao X. Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development (Cambridge, England). 140: 3323-34. PMID 23863479 DOI: 10.1242/Dev.096537  0.319
2013 Xin M, Olson EN, Bassel-Duby R. Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair. Nature Reviews. Molecular Cell Biology. 14: 529-41. PMID 23839576 DOI: 10.1038/Nrm3619  0.368
2013 Nelson BR, Wu F, Liu Y, Anderson DM, McAnally J, Lin W, Cannon SC, Bassel-Duby R, Olson EN. Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility. Proceedings of the National Academy of Sciences of the United States of America. 110: 11881-6. PMID 23818578 DOI: 10.1073/Pnas.1310571110  0.381
2013 Gan Z, Rumsey J, Hazen BC, Lai L, Leone TC, Vega RB, Xie H, Conley KE, Auwerx J, Smith SR, Olson EN, Kralli A, Kelly DP. Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism. The Journal of Clinical Investigation. 123: 2564-75. PMID 23676496 DOI: 10.1172/Jci67652  0.406
2013 Nam YJ, Song K, Olson EN. Heart repair by cardiac reprogramming. Nature Medicine. 19: 413-5. PMID 23558630 DOI: 10.1038/Nm.3147  0.46
2013 Zang T, Maksimova MA, Cowan CW, Bassel-Duby R, Olson EN, Huber KM. Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity. Molecular and Cellular Neurosciences. 56: 39-49. PMID 23511190 DOI: 10.1016/J.Mcn.2013.03.002  0.309
2013 Nam YJ, Song K, Luo X, Daniel E, Lambeth K, West K, Hill JA, DiMaio JM, Baker LA, Bassel-Duby R, Olson EN. Reprogramming of human fibroblasts toward a cardiac fate. Proceedings of the National Academy of Sciences of the United States of America. 110: 5588-93. PMID 23487791 DOI: 10.1073/Pnas.1301019110  0.441
2013 Wang Y, Tian Y, Morley MP, Lu MM, Demayo FJ, Olson EN, Morrisey EE. Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway. Developmental Cell. 24: 345-58. PMID 23449471 DOI: 10.1016/J.Devcel.2013.01.012  0.38
2013 Ye J, Llorian M, Cardona M, Rongvaux A, Moubarak RS, Comella JX, Bassel-Duby R, Flavell RA, Olson EN, Smith CW, Sanchis D. A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart. Journal of Cell Science. 126: 1682-91. PMID 23424201 DOI: 10.1242/Jcs.121384  0.511
2013 Millay DP, Olson EN. Making muscle or mitochondria by selective splicing of PGC-1α. Cell Metabolism. 17: 3-4. PMID 23312277 DOI: 10.1016/J.Cmet.2012.12.008  0.403
2013 Porrello ER, Mahmoud AI, Simpson E, Johnson BA, Grinsfelder D, Canseco D, Mammen PP, Rothermel BA, Olson EN, Sadek HA. Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family. Proceedings of the National Academy of Sciences of the United States of America. 110: 187-92. PMID 23248315 DOI: 10.1073/Pnas.1208863110  0.642
2013 Das A, Tanigawa S, Karner CM, Xin M, Lum L, Chen C, Olson EN, Perantoni AO, Carroll TJ. Erratum: Stromal–epithelial crosstalk regulates kidney progenitor cell differentiation Nature Cell Biology. 15: 1260-1260. DOI: 10.1038/Ncb2853  0.329
2012 Huang GN, Thatcher JE, McAnally J, Kong Y, Qi X, Tan W, DiMaio JM, Amatruda JF, Gerard RD, Hill JA, Bassel-Duby R, Olson EN. C/EBP transcription factors mediate epicardial activation during heart development and injury. Science (New York, N.Y.). 338: 1599-603. PMID 23160954 DOI: 10.1126/Science.1229765  0.682
2012 Hatley ME, Tang W, Garcia MR, Finkelstein D, Millay DP, Liu N, Graff J, Galindo RL, Olson EN. A mouse model of rhabdomyosarcoma originating from the adipocyte lineage. Cancer Cell. 22: 536-46. PMID 23079662 DOI: 10.1016/J.Ccr.2012.09.004  0.435
2012 Sturgeon CM, Chicha L, Ditadi A, Zhou Q, McGrath KE, Palis J, Hammond SM, Wang S, Olson EN, Keller G. Primitive erythropoiesis is regulated by miR-126 via nonhematopoietic Vcam-1+ cells. Developmental Cell. 23: 45-57. PMID 22749417 DOI: 10.1016/J.Devcel.2012.05.021  0.302
2012 Song K, Nam YJ, Luo X, Qi X, Tan W, Huang GN, Acharya A, Smith CL, Tallquist MD, Neilson EG, Hill JA, Bassel-Duby R, Olson EN. Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature. 485: 599-604. PMID 22660318 DOI: 10.1038/Nature11139  0.666
2012 Acharya A, Baek ST, Huang G, Eskiocak B, Goetsch S, Sung CY, Banfi S, Sauer MF, Olsen GS, Duffield JS, Olson EN, Tallquist MD. The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors. Development (Cambridge, England). 139: 2139-49. PMID 22573622 DOI: 10.1242/Dev.079970  0.699
2012 Liu N, Williams AH, Maxeiner JM, Bezprozvannaya S, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN. microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. The Journal of Clinical Investigation. 122: 2054-65. PMID 22546853 DOI: 10.1172/Jci62656  0.373
2012 Grueter CE, van Rooij E, Johnson BA, DeLeon SM, Sutherland LB, Qi X, Gautron L, Elmquist JK, Bassel-Duby R, Olson EN. A cardiac microRNA governs systemic energy homeostasis by regulation of MED13. Cell. 149: 671-83. PMID 22541436 DOI: 10.1016/J.Cell.2012.03.029  0.333
2012 Zeve D, Seo J, Suh JM, Stenesen D, Tang W, Berglund ED, Wan Y, Williams LJ, Lim A, Martinez MJ, McKay RM, Millay DP, Olson EN, Graff JM. Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake. Cell Metabolism. 15: 492-504. PMID 22482731 DOI: 10.1016/J.Cmet.2012.03.010  0.325
2012 Aurora AB, Mahmoud AI, Luo X, Johnson BA, van Rooij E, Matsuzaki S, Humphries KM, Hill JA, Bassel-Duby R, Sadek HA, Olson EN. MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death. The Journal of Clinical Investigation. 122: 1222-32. PMID 22426211 DOI: 10.1172/Jci59327  0.63
2012 Moresi V, Carrer M, Grueter CE, Rifki OF, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN. Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 1649-54. PMID 22307625 DOI: 10.1073/Pnas.1121159109  0.42
2012 Mokalled MH, Johnson AN, Creemers EE, Olson EN. MASTR directs MyoD-dependent satellite cell differentiation during skeletal muscle regeneration. Genes & Development. 26: 190-202. PMID 22279050 DOI: 10.1101/Gad.179663.111  0.473
2012 Ma P, Pan H, Montgomery RL, Olson EN, Schultz RM. Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development. Proceedings of the National Academy of Sciences of the United States of America. 109: E481-9. PMID 22223663 DOI: 10.1073/Pnas.1118403109  0.333
2012 Hullinger TG, Montgomery RL, Seto AG, Dickinson BA, Semus HM, Lynch JM, Dalby CM, Robinson K, Stack C, Latimer PA, Hare JM, Olson EN, van Rooij E. Inhibition of miR-15 protects against cardiac ischemic injury. Circulation Research. 110: 71-81. PMID 22052914 DOI: 10.1161/Circresaha.111.244442  0.319
2012 Srivastava D, Olson EN. Knowing in your heart what's right. Trends in Cell Biology. 7: 447-53. PMID 17709004 DOI: 10.1016/S0962-8924(97)01150-1  0.584
2012 Olson EN. Abstract IA13: MicroRNA control of muscle development and disease: from new biology to new therapeutics Cancer Research. 72: IA13-IA13. DOI: 10.1158/1538-7445.Nonrna12-Ia13  0.374
2012 Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, Wadel K, Touller C, Butler R, Robertson J, Franklin S, Smith D, Park L, Marks P, Wanker E, ... Olson E, et al. A12 HDAC4 interacts with huntington and HDAC4 reduction decreases cytoplamsic aggregation and rescues synaptic dysfunction in HD mouse models Journal of Neurology, Neurosurgery, and Psychiatry. 83. DOI: 10.1136/Jnnp-2012-303524.12  0.314
2012 Frey N, Olson EN, Hill JA. Mechanisms of stress-induced cardiac hypertrophy Muscle. 1: 481-494. DOI: 10.1016/B978-0-12-381510-1.00035-1  0.347
2012 Hill JA, Olson EN. An introduction to muscle Muscle. 1: 3-9. DOI: 10.1016/B978-0-12-381510-1.00001-6  0.373
2011 Backs J, Worst BC, Lehmann LH, Patrick DM, Jebessa Z, Kreusser MM, Sun Q, Chen L, Heft C, Katus HA, Olson EN. Selective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4. The Journal of Cell Biology. 195: 403-15. PMID 22042619 DOI: 10.1083/Jcb.201105063  0.641
2011 Xin M, Kim Y, Sutherland LB, Qi X, McAnally J, Schwartz RJ, Richardson JA, Bassel-Duby R, Olson EN. Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size. Science Signaling. 4: ra70. PMID 22028467 DOI: 10.1126/Scisignal.2002278  0.414
2011 Johnson AN, Mokalled MH, Haden TN, Olson EN. JAK/Stat signaling regulates heart precursor diversification in Drosophila. Development (Cambridge, England). 138: 4627-38. PMID 21965617 DOI: 10.1242/Dev.071464  0.446
2011 Lenoir O, Flosseau K, Ma FX, Blondeau B, Mai A, Bassel-Duby R, Ravassard P, Olson EN, Haumaitre C, Scharfmann R. Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9. Diabetes. 60: 2861-71. PMID 21953612 DOI: 10.2337/Db11-0440  0.354
2011 Montgomery RL, Hullinger TG, Semus HM, Dickinson BA, Seto AG, Lynch JM, Stack C, Latimer PA, Olson EN, van Rooij E. Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure. Circulation. 124: 1537-47. PMID 21900086 DOI: 10.1161/Circulationaha.111.030932  0.349
2011 Porrello ER, Johnson BA, Aurora AB, Simpson E, Nam YJ, Matkovich SJ, Dorn GW, van Rooij E, Olson EN. MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes. Circulation Research. 109: 670-9. PMID 21778430 DOI: 10.1161/Circresaha.111.248880  0.311
2011 Liu N, Bezprozvannaya S, Shelton JM, Frisard MI, Hulver MW, McMillan RP, Wu Y, Voelker KA, Grange RW, Richardson JA, Bassel-Duby R, Olson EN. Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy. The Journal of Clinical Investigation. 121: 3258-68. PMID 21737882 DOI: 10.1172/Jci46267  0.311
2011 Berry JM, Le V, Rotter D, Battiprolu PK, Grinsfelder B, Tannous P, Burchfield JS, Czubryt M, Backs J, Olson EN, Rothermel BA, Hill JA. Reversibility of adverse, calcineurin-dependent cardiac remodeling. Circulation Research. 109: 407-17. PMID 21700928 DOI: 10.1161/Circresaha.110.228452  0.654
2011 Chatterjee TK, Idelman G, Blanco V, Blomkalns AL, Piegore MG, Weintraub DS, Kumar S, Rajsheker S, Manka D, Rudich SM, Tang Y, Hui DY, Bassel-Duby R, Olson EN, Lingrel JB, et al. Histone deacetylase 9 is a negative regulator of adipogenic differentiation. The Journal of Biological Chemistry. 286: 27836-47. PMID 21680747 DOI: 10.1074/Jbc.M111.262964  0.39
2011 Quiat D, Voelker KA, Pei J, Grishin NV, Grange RW, Bassel-Duby R, Olson EN. Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6. Proceedings of the National Academy of Sciences of the United States of America. 108: 10196-201. PMID 21633012 DOI: 10.1073/Pnas.1107413108  0.481
2011 Caprioli A, Koyano-Nakagawa N, Iacovino M, Shi X, Ferdous A, Harvey RP, Olson EN, Kyba M, Garry DJ. Nkx2-5 represses Gata1 gene expression and modulates the cellular fate of cardiac progenitors during embryogenesis. Circulation. 123: 1633-41. PMID 21464046 DOI: 10.1161/Circulationaha.110.008185  0.446
2011 Chen Y, Wang H, Yoon SO, Xu X, Hottiger MO, Svaren J, Nave KA, Kim HA, Olson EN, Lu QR. HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nature Neuroscience. 14: 437-41. PMID 21423191 DOI: 10.1038/Nn.2780  0.348
2011 Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN, Verdin E. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. Journal of Immunology (Baltimore, Md. : 1950). 186: 4782-93. PMID 21398603 DOI: 10.4049/Jimmunol.1001179  0.377
2011 Hoofnagle MH, Neppl RL, Berzin EL, Teg Pipes GC, Olson EN, Wamhoff BW, Somlyo AV, Owens GK. Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1707-21. PMID 21357509 DOI: 10.1152/Ajpheart.01192.2010  0.438
2011 Porrello ER, Mahmoud AI, Simpson E, Hill JA, Richardson JA, Olson EN, Sadek HA. Transient regenerative potential of the neonatal mouse heart. Science (New York, N.Y.). 331: 1078-80. PMID 21350179 DOI: 10.1126/Science.1200708  0.645
2011 Li W, Li H, Sanders PN, Mohler PJ, Backs J, Olson EN, Anderson ME, Grumbach IM. The multifunctional Ca2+/calmodulin-dependent kinase II delta (CaMKIIdelta) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21. The Journal of Biological Chemistry. 286: 7990-9. PMID 21193397 DOI: 10.1074/Jbc.M110.163006  0.635
2011 Tsuchihashi T, Maeda J, Shin CH, Ivey KN, Black BL, Olson EN, Yamagishi H, Srivastava D. Hand2 function in second heart field progenitors is essential for cardiogenesis. Developmental Biology. 351: 62-9. PMID 21185281 DOI: 10.1016/J.Ydbio.2010.12.023  0.735
2011 Russell JL, Goetsch SC, Gaiano NR, Hill JA, Olson EN, Schneider JW. A dynamic notch injury response activates epicardium and contributes to fibrosis repair. Circulation Research. 108: 51-9. PMID 21106942 DOI: 10.1161/Circresaha.110.233262  0.403
2010 Porrello ER, Olson EN. Building a new heart from old parts: stem cell turnover in the aging heart. Circulation Research. 107: 1292-4. PMID 21106945 DOI: 10.1161/Circresaha.110.235168  0.358
2010 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE. Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Developmental Cell. 19: 807-18. PMID 21093383 DOI: 10.1016/J.Devcel.2010.10.015  0.362
2010 Patrick DM, Montgomery RL, Qi X, Obad S, Kauppinen S, Hill JA, van Rooij E, Olson EN. Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. The Journal of Clinical Investigation. 120: 3912-6. PMID 20978354 DOI: 10.1172/Jci43604  0.347
2010 Small EM, Sutherland LB, Rajagopalan KN, Wang S, Olson EN. MicroRNA-218 regulates vascular patterning by modulation of Slit-Robo signaling. Circulation Research. 107: 1336-44. PMID 20947829 DOI: 10.1161/Circresaha.110.227926  0.331
2010 Konno T, Chen D, Wang L, Wakimoto H, Teekakirikul P, Nayor M, Kawana M, Eminaga S, Gorham JM, Pandya K, Smithies O, Naya FJ, Olson EN, Seidman JG, Seidman CE. Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 107: 18097-102. PMID 20923879 DOI: 10.1073/Pnas.1012826107  0.437
2010 Moresi V, Williams AH, Meadows E, Flynn JM, Potthoff MJ, McAnally J, Shelton JM, Backs J, Klein WH, Richardson JA, Bassel-Duby R, Olson EN. Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases. Cell. 143: 35-45. PMID 20887891 DOI: 10.1016/J.Cell.2010.09.004  0.784
2010 Frost RJ, Olson EN. Separating the good and evil of cardiac growth by CIB1 and calcineurin. Cell Metabolism. 12: 205-6. PMID 20816084 DOI: 10.1016/J.Cmet.2010.08.007  0.346
2010 Simsek T, Kocabas F, Zheng J, Deberardinis RJ, Mahmoud AI, Olson EN, Schneider JW, Zhang CC, Sadek HA. The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell. 7: 380-90. PMID 20804973 DOI: 10.1016/J.Stem.2010.07.011  0.746
2010 Tukel T, Šošić D, Al-Gazali LI, Erazo M, Casasnovas J, Franco HL, Richardson JA, Olson EN, Cadilla CL, Desnick RJ. Homozygous nonsense mutations in TWIST2 cause setleis syndrome American Journal of Human Genetics. 87: 289-296. PMID 20691403 DOI: 10.1016/J.Ajhg.2010.07.009  0.323
2010 Small EM, Thatcher JE, Sutherland LB, Kinoshita H, Gerard RD, Richardson JA, Dimaio JM, Sadek H, Kuwahara K, Olson EN. Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction Circulation Research. 107: 294-304. PMID 20558820 DOI: 10.1161/Circresaha.110.223172  0.728
2010 Frost RJA, Hamra FK, Richardson JA, Qi X, Bassel-Duby R, Olson EN. MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs Proceedings of the National Academy of Sciences of the United States of America. 107: 11847-11852. PMID 20547853 DOI: 10.1073/Pnas.1007158107  0.328
2010 Xu L, Lai D, Cheng J, Lim HJ, Keskanokwong T, Backs J, Olson EN, Wang Y. Alterations of L-type calcium current and cardiac function in CaMKII{delta} knockout mice. Circulation Research. 107: 398-407. PMID 20538682 DOI: 10.1161/Circresaha.110.222562  0.575
2010 Shrivastava S, Srivastava D, Olson EN, Dimaio JM, Bock-Marquette I. Thymosin β4 and cardiac repair Annals of the New York Academy of Sciences. 1194: 87-96. PMID 20536454 DOI: 10.1111/J.1749-6632.2010.05468.X  0.559
2010 Mokalled MH, Johnson A, Kim Y, Oh J, Olson EN. Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development. Development (Cambridge, England). 137: 2365-74. PMID 20534669 DOI: 10.1242/Dev.047605  0.35
2010 Olson EN, Nordheim A. Linking actin dynamics and gene transcription to drive cellular motile functions Nature Reviews Molecular Cell Biology. 11: 353-365. PMID 20414257 DOI: 10.1038/Nrm2890  0.377
2010 Liu N, Olson EN. MicroRNA Regulatory Networks in Cardiovascular Development Developmental Cell. 18: 510-525. PMID 20412767 DOI: 10.1016/J.Devcel.2010.03.010  0.364
2010 Jawerka M, Colak D, Dimou L, Spiller C, Lagger S, Montgomery RL, Olson EN, Wurst W, Gttlicher M, Götz M. The specific role of histone deacetylase 2 in adult neurogenesis Neuron Glia Biology. 6: 93-107. PMID 20388229 DOI: 10.1017/S1740925X10000049  0.351
2010 Haberland M, Carrer M, Mokalled MH, Montgomery RL, Olson EN. Redundant control of adipogenesis by histone deacetylases 1 and 2 Journal of Biological Chemistry. 285: 14663-14670. PMID 20190228 DOI: 10.1074/Jbc.M109.081679  0.355
2010 Small EM, O'Rourke JR, Moresi V, Sutherland LB, McAnally J, Gerard RD, Richardson JA, Olson EN. Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486 Proceedings of the National Academy of Sciences of the United States of America. 107: 4218-4223. PMID 20142475 DOI: 10.1073/Pnas.1000300107  0.338
2010 Shimizu E, Selvamurugan N, Westendorf JJ, Olson EN, Partridge NC. HDAC4 represses matrix metalloproteinase-13 transcription in osteoblastic cells, and parathyroid hormone controls this repression Journal of Biological Chemistry. 285: 9616-9626. PMID 20097749 DOI: 10.1074/Jbc.M109.094862  0.331
2010 Seeger TS, Frank D, Rohr C, Will R, Just S, Grund C, Lyon R, Luedde M, Koegl M, Sheikh F, Rottbauer W, Franke WW, Katus HA, Olson EN, Frey N. Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo. Circulation Research. 106: 880-90. PMID 20093627 DOI: 10.1161/Circresaha.109.213256  0.468
2010 Backs J, Stein P, Backs T, Duncan FE, Grueter CE, McAnally J, Qi X, Schultz RM, Olson EN. The γ isoform of CaM kinase II controls mouse egg activation by regulating cell cycle resumption Proceedings of the National Academy of Sciences of the United States of America. 107: 81-86. PMID 19966304 DOI: 10.1073/Pnas.0912658106  0.587
2010 Van Rooij E, Fielitz J, Sutherland LB, Thijssen VL, Crijns HJ, Dimaio MJ, Shelton J, De Windt LJ, Hill JA, Olson EN. Myocyte enhancer factor 2 and class ii histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor Circulation Research. 106: 155-165. PMID 19893013 DOI: 10.1161/Circresaha.109.207084  0.39
2009 Williams AH, Valdez G, Moresi V, Qi X, McAnally J, Elliott JL, Bassel-Duby R, Sanes JR, Olson EN. MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science (New York, N.Y.). 326: 1549-54. PMID 20007902 DOI: 10.1126/Science.1181046  0.314
2009 Zernecke A, Bidzhekov K, Noels H, Shagdarsuren E, Gan L, Denecke B, Hristov M, Köppel T, Jahantigh MN, Lutgens E, Wang S, Olson EN, Schober A, Weber C. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Science Signaling. 2: ra81. PMID 19996457 DOI: 10.1126/Scisignal.2000610  0.314
2009 van Rooij E, Quiat D, Johnson BA, Sutherland LB, Qi X, Richardson JA, Kelm RJ, Olson EN. A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Developmental Cell. 17: 662-73. PMID 19922871 DOI: 10.1016/J.Devcel.2009.10.013  0.405
2009 Sag CM, Wadsack DP, Khabbazzadeh S, Abesser M, Grefe C, Neumann K, Opiela MK, Backs J, Olson EN, Brown JH, Neef S, Maier SK, Maier LS. Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure. Circulation. Heart Failure. 2: 664-75. PMID 19919992 DOI: 10.1161/Circheartfailure.109.865279  0.595
2009 Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, Tabas I. Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. The Journal of Clinical Investigation. 119: 2925-41. PMID 19741297 DOI: 10.1172/Jci38857  0.558
2009 Koshiba-Takeuchi K, Mori AD, Kaynak BL, Cebra-Thomas J, Sukonnik T, Georges RO, Latham S, Beck L, Beck L, Henkelman RM, Black BL, Olson EN, Wade J, Takeuchi JK, Nemer M, et al. Reptilian heart development and the molecular basis of cardiac chamber evolution. Nature. 461: 95-8. PMID 19727199 DOI: 10.1038/Nature08324  0.659
2009 Xin M, Small EM, Sutherland LB, Qi X, McAnally J, Plato CF, Richardson JA, Bassel-Duby R, Olson EN. MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury. Genes & Development. 23: 2166-78. PMID 19720868 DOI: 10.1101/Gad.1842409  0.306
2009 Haberland M, Mokalled MH, Montgomery RL, Olson EN. Epigenetic control of skull morphogenesis by histone deacetylase 8 Genes and Development. 23: 1625-1630. PMID 19605684 DOI: 10.1101/Gad.1809209  0.369
2009 Munshi NV, McAnally J, Bezprozvannaya S, Berry JM, Richardson JA, Hill JA, Olson EN. Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay Development. 136: 2665-2674. PMID 19592579 DOI: 10.1242/Dev.038562  0.428
2009 Schwieger M, Schüler A, Forster M, Engelmann A, Arnold MA, Delwel R, Valk PJ, Löhler J, Slany RK, Olson EN, Stocking C. Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C Blood. 114: 2476-2488. PMID 19584403 DOI: 10.1182/Blood-2008-05-158196  0.404
2009 Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, Van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR. HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the Β-catenin-TCF interaction Nature Neuroscience. 12: 829-838. PMID 19503085 DOI: 10.1038/Nn.2333  0.388
2009 Haberland M, Johnson A, Mokalled MH, Montgomery RL, Olson EN. Genetic dissection of histone deacetylase requirement in tumor cells Proceedings of the National Academy of Sciences of the United States of America. 106: 7751-7755. PMID 19416910 DOI: 10.1073/Pnas.0903139106  0.309
2009 Bock-Marquette I, Shrivastava S, Pipes GC, Thatcher JE, Blystone A, Shelton JM, Galindo CL, Melegh B, Srivastava D, Olson EN, DiMaio JM. Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. Journal of Molecular and Cellular Cardiology. 46: 728-38. PMID 19358334 DOI: 10.1016/J.Yjmcc.2009.01.017  0.561
2009 Williams AH, Liu N, van Rooij E, Olson EN. MicroRNA control of muscle development and disease. Current Opinion in Cell Biology. 21: 461-9. PMID 19278845 DOI: 10.1016/J.Ceb.2009.01.029  0.492
2009 Luckey SW, Walker LA, Smyth T, Mansoori J, Messmer-Kratzsch A, Rosenzweig A, Olson EN, Leinwand LA. The role of Akt/GSK-3β signaling in familial hypertrophic cardiomyopathy Journal of Molecular and Cellular Cardiology. 46: 739-747. PMID 19233194 DOI: 10.1016/J.Yjmcc.2009.02.010  0.385
2009 Gekas C, Rhodes KE, Gereige LM, Helgadottir H, Ferrari R, Kurdistani SK, Montecino-Rodriguez E, Bassel-Duby R, Olson E, Krivtsov AV, Armstrong S, Orkin SH, Pellegrini M, Mikkola HK. Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. Blood. 113: 3461-71. PMID 19211936 DOI: 10.1182/Blood-2008-07-167577  0.399
2009 Liu N, Barbosa AC, Chapman SL, Bezprozvannaya S, Qi X, Richardson JA, Yanagisawa H, Olson EN. DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis Development. 136: 933-942. PMID 19211672 DOI: 10.1242/Dev.034025  0.355
2009 Van Rooij E, Olson EN. Editorial: Searching for MiR-acles in cardiac fibrosis Circulation Research. 104: 138-140. PMID 19179664 DOI: 10.1161/Circresaha.108.192492  0.385
2009 Backs J, Backs T, Neef S, Kreusser MM, Lehmann LH, Patrick DM, Grueter CE, Qi X, Richardson JA, Hill JA, Katus HA, Bassel-Duby R, Maier LS, Olson EN. The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proceedings of the National Academy of Sciences of the United States of America. 106: 2342-7. PMID 19179290 DOI: 10.1073/Pnas.0813013106  0.639
2009 Ferdous A, Caprioli A, Iacovino M, Martin CM, Morris J, Richardson JA, Latif S, Hammer RE, Harvey RP, Olson EN, Kyba M, Garry DJ. Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo. Proceedings of the National Academy of Sciences of the United States of America. 106: 814-9. PMID 19129488 DOI: 10.1073/Pnas.0807583106  0.446
2009 Haberland M, Montgomery RL, Olson EN. The many roles of histone deacetylases in development and physiology: Implications for disease and therapy Nature Reviews Genetics. 10: 32-42. PMID 19065135 DOI: 10.1038/Nrg2485  0.363
2009 Takemori H, Hashimoto YK, Nakae J, Olson EN, Okamoto M. Inactivation of HDAC5 by SIK1 in AICAR-treated C2C12 myoblasts Endocrine Journal. 56: 121-130. PMID 18946175 DOI: 10.1507/Endocrj.K08E-173  0.382
2009 Stein P, Backs T, Backs J, Duncan FE, McAnally J, Qi X, Schultz RM, Olson EN. Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Gamma Is the Main Integrator of Calcium Signaling at Fertilization in the Mouse. Biology of Reproduction. 81: 132-132. DOI: 10.1093/Biolreprod/81.S1.132  0.548
2009 Koshiba-Takeuchi K, Mori AD, Kaynak BL, Cebra-Thomas J, Sukonnik T, Georges RO, Latham S, Beck L, Henkelman RM, Black BL, Olson EN, Wade J, Takeuchi JK, Nemer M, Gilbert SF, et al. Erratum: Reptilian heart development and the molecular basis of cardiac chamber evolution (Nature (2009) 461 (95-98)) Nature. 461. DOI: 10.1038/Nature08464  0.624
2008 Sharabi AB, Aldrich M, Sosic D, Olson EN, Friedman AD, Lee SH, Chen SY. Twist-2 controls myeloid lineage development and function. Plos Biology. 6: e316. PMID 19090621 DOI: 10.1371/Journal.Pbio.0060316  0.373
2008 Liu N, Bezprozvannaya S, Williams AH, Qi X, Richardson JA, Bassel-Duby R, Olson EN. microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes & Development. 22: 3242-54. PMID 19015276 DOI: 10.1101/Gad.1738708  0.339
2008 Yi P, Johnson AN, Han Z, Wu J, Olson EN. Heterotrimeric G proteins regulate a noncanonical function of septate junction proteins to maintain cardiac integrity in Drosophila. Developmental Cell. 15: 704-13. PMID 19000835 DOI: 10.1016/J.Devcel.2008.10.001  0.578
2008 van Rooij E, Marshall WS, Olson EN. Toward microRNA-based therapeutics for heart disease: the sense in antisense. Circulation Research. 103: 919-28. PMID 18948630 DOI: 10.1161/Circresaha.108.183426  0.435
2008 Frey N, Frank D, Lippl S, Kuhn C, Kögler H, Barrientos T, Rohr C, Will R, Müller OJ, Weiler H, Bassel-Duby R, Katus HA, Olson EN. Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation. The Journal of Clinical Investigation. 118: 3598-608. PMID 18846255 DOI: 10.1172/Jci36277  0.434
2008 Montgomery RL, Potthoff MJ, Haberland M, Qi X, Matsuzaki S, Humphries KM, Richardson JA, Bassel-Duby R, Olson EN. Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice Journal of Clinical Investigation. 118: 3588-3597. PMID 18830415 DOI: 10.1172/Jci35847  0.702
2008 van Rooij E, Sutherland LB, Thatcher JE, DiMaio JM, Naseem RH, Marshall WS, Hill JA, Olson EN. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 13027-32. PMID 18723672 DOI: 10.1073/Pnas.0805038105  0.345
2008 Renthal W, Carle TL, Maze I, Covington HE, Truong HT, Alibhai I, Kumar A, Montgomery RL, Olson EN, Nestler EJ. Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7344-9. PMID 18632938 DOI: 10.1523/Jneurosci.1043-08.2008  0.351
2008 Wang S, Li X, Parra M, Verdin E, Bassel-Duby R, Olson EN. Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7. Proceedings of the National Academy of Sciences of the United States of America. 105: 7738-43. PMID 18509061 DOI: 10.1073/Pnas.0802857105  0.317
2008 Majdzadeh N, Wang L, Morrison BE, Bassel-Duby R, Olson EN, D'Mello SR. HDAC4 inhibits cell-cycle progression and protects neurons from cell death. Developmental Neurobiology. 68: 1076-92. PMID 18498087 DOI: 10.1002/Dneu.20637  0.322
2008 Sadek H, Hannack B, Choe E, Wang J, Latif S, Garry MG, Garry DJ, Longgood J, Frantz DE, Olson EN, Hsieh J, Schneider JW. Cardiogenic small molecules that enhance myocardial repair by stem cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 6063-8. PMID 18420817 DOI: 10.1073/Pnas.0711507105  0.665
2008 Barth AS, Kizana E, Smith RR, Terrovitis J, Dong P, Leppo MK, Zhang Y, Miake J, Olson EN, Schneider JW, Abraham MR, Marbán E. Lentiviral vectors bearing the cardiac promoter of the Na+-Ca2+ exchanger report cardiogenic differentiation in stem cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 957-64. PMID 18388932 DOI: 10.1038/Mt.2008.30  0.404
2008 Kim MS, Fielitz J, McAnally J, Shelton JM, Lemon DD, McKinsey TA, Richardson JA, Bassel-Duby R, Olson EN. Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances muscle performance Molecular and Cellular Biology. 28: 3600-3609. PMID 18378694 DOI: 10.1128/Mcb.00189-08  0.404
2008 Chang HH, Wang W, Bong SJ, Wong C, Hausser A, Pfizenmaier K, McKinsey TA, Olson EN, Jin ZG. Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis Journal of Biological Chemistry. 283: 14590-14599. PMID 18332134 DOI: 10.1074/Jbc.M800264200  0.355
2008 Backs J, Backs T, Bezprozvannaya S, McKinsey TA, Olson EN. Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4. Molecular and Cellular Biology. 28: 3437-45. PMID 18332106 DOI: 10.1128/Mcb.01611-07  0.605
2008 Schüler A, Schwieger M, Engelmann A, Weber K, Horn S, Müller U, Arnold MA, Olson EN, Stocking C. The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate Blood. 111: 4532-4541. PMID 18326819 DOI: 10.1182/Blood-2007-10-116343  0.436
2008 van Rooij E, Liu N, Olson EN. MicroRNAs flex their muscles Trends in Genetics. 24: 159-166. PMID 18325627 DOI: 10.1016/J.Tig.2008.01.007  0.499
2008 Fielitz J, Kim MS, Shelton JM, Qi X, Hill JA, Richardson JA, Bassel-Duby R, Olson EN. Requirement of protein kinase D1 for pathological cardiac remodeling Proceedings of the National Academy of Sciences of the United States of America. 105: 3059-3063. PMID 18287012 DOI: 10.1073/Pnas.0712265105  0.43
2008 Stupka N, Schertzer JD, Bassel-Duby R, Olson EN, Lynch GS. Stimulation of calcineurin Aalpha activity attenuates muscle pathophysiology in mdx dystrophic mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R983-92. PMID 18199592 DOI: 10.1152/Ajpregu.00375.2007  0.41
2008 Kim Y, Phan D, van Rooij E, Wang DZ, McAnally J, Qi X, Richardson JA, Hill JA, Bassel-Duby R, Olson EN. The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. The Journal of Clinical Investigation. 118: 124-32. PMID 18079970 DOI: 10.1172/Jci33255  0.651
2008 Potthoff MJ, Olson EN, Bassel-Duby R. Skeletal muscle remodeling. Current Opinion in Rheumatology. 19: 542-9. PMID 17917533 DOI: 10.1097/Bor.0B013E3282Efb761  0.712
2008 Kuwahara K, Nakao K, Olson E. MRTF-A, a rho-dependent co-activator of SRF, mediates mechanical stress-induced hypertrophic gene activation Journal of Cardiac Failure. 14. DOI: 10.1016/J.Cardfail.2008.07.184  0.311
2007 Liu N, Williams AH, Kim Y, McAnally J, Bezprozvannaya S, Sutherland LB, Richardson JA, Bassel-Duby R, Olson EN. An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133. Proceedings of the National Academy of Sciences of the United States of America. 104: 20844-9. PMID 18093911 DOI: 10.1073/Pnas.0710558105  0.412
2007 Rybkin II, Kim MS, Bezprozvannaya S, Qi X, Richardson JA, Plato CF, Hill JA, Bassel-Duby R, Olson EN. Regulation of atrial natriuretic peptide secretion by a novel Ras-like protein. The Journal of Cell Biology. 179: 527-37. PMID 17984325 DOI: 10.1083/Jcb.200707101  0.35
2007 Potthoff MJ, Olson EN. MEF2: A central regulator of diverse developmental programs Development. 134: 4131-4140. PMID 17959722 DOI: 10.1242/Dev.008367  0.713
2007 Long X, Creemers EE, Wang DZ, Olson EN, Miano JM. Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation. Proceedings of the National Academy of Sciences of the United States of America. 104: 16570-5. PMID 17940050 DOI: 10.1073/Pnas.0708253104  0.659
2007 Zhang T, Kohlhaas M, Backs J, Mishra S, Phillips W, Dybkova N, Chang S, Ling H, Bers DM, Maier LS, Olson EN, Brown JH. CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses. The Journal of Biological Chemistry. 282: 35078-87. PMID 17923476 DOI: 10.1074/Jbc.M707083200  0.655
2007 Tao R, de Zoeten EF, Ozkaynak E, Chen C, Wang L, Porrett PM, Li B, Turka LA, Olson EN, Greene MI, Wells AD, Hancock WW. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nature Medicine. 13: 1299-307. PMID 17922010 DOI: 10.1038/Nm1652  0.352
2007 Potthoff MJ, Arnold MA, McAnally J, Richardson JA, Bassel-Duby R, Olson EN. Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c Molecular and Cellular Biology. 27: 8143-8151. PMID 17875930 DOI: 10.1128/Mcb.01187-07  0.73
2007 Van Rooij E, Olson EN. microRNAs put their signatures on the heart Physiological Genomics. 31: 365-366. PMID 17848602 DOI: 10.1152/Physiolgenomics.00206.2007  0.305
2007 Xu X, Ha CH, Wong C, Wang W, Hausser A, Pfizenmaier K, Olson EN, McKinsey TA, Jin ZG. Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2355-62. PMID 17823368 DOI: 10.1161/Atvbaha.107.151704  0.351
2007 Fielitz J, Kim MS, Shelton JM, Latif S, Spencer JA, Glass DJ, Richardson JA, Bassel-Duby R, Olson EN. Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3. The Journal of Clinical Investigation. 117: 2486-95. PMID 17786241 DOI: 10.1172/Jci32827  0.42
2007 Potthoff MJ, Wu H, Arnold MA, Shelton JM, Backs J, McAnally J, Richardson JA, Bassel-Duby R, Olson EN. Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. The Journal of Clinical Investigation. 117: 2459-67. PMID 17786239 DOI: 10.1172/Jci31960  0.793
2007 van Rooij E, Olson EN. MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. The Journal of Clinical Investigation. 117: 2369-76. PMID 17786230 DOI: 10.1172/Jci33099  0.389
2007 Barbosa AC, Funato N, Chapman S, McKee MD, Richardson JA, Olson EN, Yanagisawa H. Hand transcription factors cooperatively regulate development of the distal midline mesenchyme. Developmental Biology. 310: 154-68. PMID 17764670 DOI: 10.1016/J.Ydbio.2007.07.036  0.385
2007 Wu H, Kao SC, Barrientos T, Baldwin SH, Olson EN, Crabtree GR, Zhou B, Chang CP. Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development. The Journal of Biological Chemistry. 282: 30673-9. PMID 17693409 DOI: 10.1074/Jbc.M703622200  0.464
2007 Montgomery RL, Davis CA, Potthoff MJ, Haberland M, Fielitz J, Qi X, Hill JA, Richardson JA, Olson EN. Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. Genes & Development. 21: 1790-802. PMID 17639084 DOI: 10.1101/Gad.1563807  0.737
2007 Davies KJ, Ermak G, Rothermel BA, Pritchard M, Heitman J, Ahnn J, Henrique-Silva F, Crawford D, Canaider S, Strippoli P, Carinci P, Min KT, Fox DS, Cunningham KW, Bassel-Duby R, ... Olson EN, et al. Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3023-8. PMID 17595344 DOI: 10.1096/Fj.06-7246Com  0.44
2007 Murchison ND, Price BA, Conner DA, Keene DR, Olson EN, Tabin CJ, Schweitzer R. Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons. Development (Cambridge, England). 134: 2697-708. PMID 17567668 DOI: 10.1242/Dev.001933  0.426
2007 Stupka N, Schertzer JD, Bassel-Duby R, Olson EN, Lynch GS. Calcineurin-A alpha activation enhances the structure and function of regenerating muscles after myotoxic injury. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R686-94. PMID 17475677 DOI: 10.1152/Ajpregu.00612.2006  0.421
2007 Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN. Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proceedings of the National Academy of Sciences of the United States of America. 104: 7975-80. PMID 17468400 DOI: 10.1073/Pnas.0702447104  0.645
2007 Kuwahara K, Teg Pipes GC, McAnally J, Richardson JA, Hill JA, Bassel-Duby R, Olson EN. Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity. The Journal of Clinical Investigation. 117: 1324-34. PMID 17415416 DOI: 10.1172/Jci31240  0.477
2007 van Rooij E, Sutherland LB, Qi X, Richardson JA, Hill J, Olson EN. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science (New York, N.Y.). 316: 575-9. PMID 17379774 DOI: 10.1126/Science.1139089  0.414
2007 Fielitz J, van Rooij E, Spencer JA, Shelton JM, Latif S, van der Nagel R, Bezprozvannaya S, de Windt L, Richardson JA, Bassel-Duby R, Olson EN. Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction. Proceedings of the National Academy of Sciences of the United States of America. 104: 4377-82. PMID 17360532 DOI: 10.1073/Pnas.0611726104  0.434
2007 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN. MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Developmental Cell. 12: 377-89. PMID 17336904 DOI: 10.1016/J.Devcel.2007.02.004  0.368
2007 Li H, Liang J, Castrillon DH, DePinho RA, Olson EN, Liu ZP. FoxO4 regulates tumor necrosis factor alpha-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcription. Molecular and Cellular Biology. 27: 2676-86. PMID 17242183 DOI: 10.1128/Mcb.01748-06  0.377
2007 Barrientos T, Frank D, Kuwahara K, Bezprozvannaya S, Pipes GC, Bassel-Duby R, Richardson JA, Katus HA, Olson EN, Frey N. Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin. The Journal of Biological Chemistry. 282: 8393-403. PMID 17194709 DOI: 10.1074/Jbc.M607549200  0.461
2007 Garry DJ, Olson EN. A common progenitor at the heart of development. Cell. 127: 1101-4. PMID 17174889 DOI: 10.1016/J.Cell.2006.11.031  0.423
2007 Wang J, Li A, Wang Z, Feng X, Olson EN, Schwartz RJ. Myocardin sumoylation transactivates cardiogenic genes in pluripotent 10T1/2 fibroblasts. Molecular and Cellular Biology. 27: 622-32. PMID 17101795 DOI: 10.1128/Mcb.01160-06  0.706
2007 Haberland M, Arnold MA, McAnally J, Phan D, Kim Y, Olson EN. Regulation of HDAC9 gene expression by MEF2 establishes a negative-feedback loop in the transcriptional circuitry of muscle differentiation. Molecular and Cellular Biology. 27: 518-25. PMID 17101791 DOI: 10.1128/Mcb.01415-06  0.512
2007 Luckey SW, Mansoori J, Fair K, Antos CL, Olson EN, Leinwand LA. Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males. American Journal of Physiology. Heart and Circulatory Physiology. 292: H838-45. PMID 17012357 DOI: 10.1152/Ajpheart.00615.2006  0.319
2007 Bassel-Duby R, Olson EN. Signaling pathways in skeletal muscle remodeling. Annual Review of Biochemistry. 75: 19-37. PMID 16756483 DOI: 10.1146/Annurev.Biochem.75.103004.142622  0.432
2007 Kuwahara K, Nakao K, Olson EN. STARS is a Mediator of MEF2 Signaling and SRF Activity During Cardiac Remodeling Journal of Cardiac Failure. 13. DOI: 10.1016/J.Cardfail.2007.06.267  0.351
2006 van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD, Richardson JA, Olson EN. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proceedings of the National Academy of Sciences of the United States of America. 103: 18255-60. PMID 17108080 DOI: 10.1073/Pnas.0608791103  0.368
2006 Kuwahara K, Wang Y, McAnally J, Richardson JA, Bassel-Duby R, Hill JA, Olson EN. TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. The Journal of Clinical Investigation. 116: 3114-26. PMID 17099778 DOI: 10.1172/Jci27702  0.459
2006 Liu N, Olson EN. Coactivator control of cardiovascular growth and remodeling. Current Opinion in Cell Biology. 18: 715-22. PMID 17046230 DOI: 10.1016/J.Ceb.2006.10.003  0.431
2006 Creemers EE, Sutherland LB, McAnally J, Richardson JA, Olson EN. Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development. Development (Cambridge, England). 133: 4245-56. PMID 17021041 DOI: 10.1242/Dev.02610  0.563
2006 Olson EN, Backs J, McKinsey TA. Control of cardiac hypertrophy and heart failure by histone acetylation/deacetylation. Novartis Foundation Symposium. 274: 3-12; discussion 13-. PMID 17019803 DOI: 10.1002/0470029331.Ch2  0.659
2006 Olson EN. Gene regulatory networks in the evolution and development of the heart. Science (New York, N.Y.). 313: 1922-7. PMID 17008524 DOI: 10.1126/Science.1132292  0.399
2006 Khoo MS, Li J, Singh MV, Yang Y, Kannankeril P, Wu Y, Grueter CE, Guan X, Oddis CV, Zhang R, Mendes L, Ni G, Madu EC, Yang J, Bass M, ... ... Olson EN, et al. Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy. Circulation. 114: 1352-9. PMID 16982937 DOI: 10.1161/Circulationaha.106.644583  0.381
2006 Bush EW, Hood DB, Papst PJ, Chapo JA, Minobe W, Bristow MR, Olson EN, McKinsey TA. Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling. The Journal of Biological Chemistry. 281: 33487-96. PMID 16950785 DOI: 10.1074/Jbc.M605536200  0.398
2006 Galindo RL, Allport JA, Olson EN. A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR. Proceedings of the National Academy of Sciences of the United States of America. 103: 13439-44. PMID 16938866 DOI: 10.1073/Pnas.0605926103  0.401
2006 Chang S, Young BD, Li S, Qi X, Richardson JA, Olson EN. Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell. 126: 321-34. PMID 16873063 DOI: 10.1016/J.Cell.2006.05.040  0.362
2006 Yi P, Han Z, Li X, Olson EN. The mevalonate pathway controls heart formation in Drosophila by isoprenylation of Ggamma1. Science (New York, N.Y.). 313: 1301-3. PMID 16857902 DOI: 10.1126/Science.1127704  0.591
2006 Li S, Chang S, Qi X, Richardson JA, Olson EN. Requirement of a myocardin-related transcription factor for development of mammary myoepithelial cells. Molecular and Cellular Biology. 26: 5797-808. PMID 16847332 DOI: 10.1128/Mcb.00211-06  0.478
2006 Xin M, Davis CA, Molkentin JD, Lien CL, Duncan SA, Richardson JA, Olson EN. A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proceedings of the National Academy of Sciences of the United States of America. 103: 11189-94. PMID 16847256 DOI: 10.1073/Pnas.0604604103  0.626
2006 Sharif MN, Sosic D, Rothlin CV, Kelly E, Lemke G, Olson EN, Ivashkiv LB. Twist mediates suppression of inflammation by type I IFNs and Axl. The Journal of Experimental Medicine. 203: 1891-901. PMID 16831897 DOI: 10.1084/Jem.20051725  0.307
2006 Creemers EE, Sutherland LB, Oh J, Barbosa AC, Olson EN. Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR. Molecular Cell. 23: 83-96. PMID 16818234 DOI: 10.1016/J.Molcel.2006.05.026  0.493
2006 Stupka N, Plant DR, Schertzer JD, Emerson TM, Bassel-Duby R, Olson EN, Lynch GS. Activated calcineurin ameliorates contraction-induced injury to skeletal muscles of mdx dystrophic mice. The Journal of Physiology. 575: 645-56. PMID 16793906 DOI: 10.1113/Jphysiol.2006.108472  0.408
2006 Pipes GC, Creemers EE, Olson EN. The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. Genes & Development. 20: 1545-56. PMID 16778073 DOI: 10.1101/Gad.1428006  0.444
2006 Backs J, Song K, Bezprozvannaya S, Chang S, Olson EN. CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. The Journal of Clinical Investigation. 116: 1853-64. PMID 16767219 DOI: 10.1172/Jci27438  0.631
2006 Kong Y, Tannous P, Lu G, Berenji K, Rothermel BA, Olson EN, Hill JA. Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation. 113: 2579-88. PMID 16735673 DOI: 10.1161/Circulationaha.106.625467  0.388
2006 Song K, Backs J, McAnally J, Qi X, Gerard RD, Richardson JA, Hill JA, Bassel-Duby R, Olson EN. The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. Cell. 125: 453-66. PMID 16678093 DOI: 10.1016/J.Cell.2006.02.048  0.677
2006 Harrison BC, Kim MS, van Rooij E, Plato CF, Papst PJ, Vega RB, McAnally JA, Richardson JA, Bassel-Duby R, Olson EN, McKinsey TA. Regulation of cardiac stress signaling by protein kinase d1. Molecular and Cellular Biology. 26: 3875-88. PMID 16648482 DOI: 10.1128/Mcb.26.10.3875-3888.2006  0.438
2006 Morrison BE, Majdzadeh N, Zhang X, Lyles A, Bassel-Duby R, Olson EN, D'Mello SR. Neuroprotection by histone deacetylase-related protein. Molecular and Cellular Biology. 26: 3550-64. PMID 16611996 DOI: 10.1128/Mcb.26.9.3550-3564.2006  0.329
2006 Xing W, Zhang TC, Cao D, Wang Z, Antos CL, Li S, Wang Y, Olson EN, Wang DZ. Myocardin induces cardiomyocyte hypertrophy. Circulation Research. 98: 1089-97. PMID 16556869 DOI: 10.1161/01.Res.0000218781.23144.3E  0.774
2006 Davis CA, Haberland M, Arnold MA, Sutherland LB, McDonald OG, Richardson JA, Childs G, Harris S, Owens GK, Olson EN. PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells. Molecular and Cellular Biology. 26: 2626-36. PMID 16537907 DOI: 10.1128/Mcb.26.7.2626-2636.2006  0.527
2006 Iyer D, Chang D, Marx J, Wei L, Olson EN, Parmacek MS, Balasubramanyam A, Schwartz RJ. Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs. Proceedings of the National Academy of Sciences of the United States of America. 103: 4516-21. PMID 16537394 DOI: 10.1073/Pnas.0505338103  0.426
2006 Wu X, Zhang T, Bossuyt J, Li X, McKinsey TA, Dedman JR, Olson EN, Chen J, Brown JH, Bers DM. Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. The Journal of Clinical Investigation. 116: 675-82. PMID 16511602 DOI: 10.1172/Jci27374  0.37
2006 Han Z, Yi P, Li X, Olson EN. Hand, an evolutionarily conserved bHLH transcription factor required for Drosophila cardiogenesis and hematopoiesis. Development (Cambridge, England). 133: 1175-82. PMID 16467358 DOI: 10.1242/Dev.02285  0.629
2006 Matthews SA, Liu P, Spitaler M, Olson EN, McKinsey TA, Cantrell DA, Scharenberg AM. Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes. Molecular and Cellular Biology. 26: 1569-77. PMID 16449666 DOI: 10.1128/Mcb.26.4.1569-1577.2006  0.322
2006 Knapp JR, Davie JK, Myer A, Meadows E, Olson EN, Klein WH. Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size. Development (Cambridge, England). 133: 601-10. PMID 16407395 DOI: 10.1242/Dev.02249  0.448
2006 Backs J, Olson EN. Control of cardiac growth by histone acetylation/deacetylation. Circulation Research. 98: 15-24. PMID 16397154 DOI: 10.1161/01.Res.0000197782.21444.8F  0.646
2006 BOURAJJAJ M, ARMAND A, RYBKIN I, BASSELDUBY R, OLSON E, MOLKENTIN J, DEWINDT L. 423 Genome wide expression profiling of NFAT transcriptional activity in a ventricular muscle cell line identifies GATA4 as an NFAT target gene in a feedforward mechanism driving cardiomyocyte hypertrophy European Journal of Heart Failure Supplements. 5: 99-99. DOI: 10.1016/S1567-4215(06)80285-7  0.608
2005 Kwon C, Han Z, Olson EN, Srivastava D. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 18986-91. PMID 16357195 DOI: 10.1073/Pnas.0509535102  0.641
2005 Murakami M, Nakagawa M, Olson EN, Nakagawa O. A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome. Proceedings of the National Academy of Sciences of the United States of America. 102: 18034-9. PMID 16332960 DOI: 10.1073/Pnas.0509109102  0.43
2005 Pipes GC, Sinha S, Qi X, Zhu CH, Gallardo TD, Shelton J, Creemers EE, Sutherland L, Richardson JA, Garry DJ, Wright WE, Owens GK, Olson EN. Stem cells and their derivatives can bypass the requirement of myocardin for smooth muscle gene expression. Developmental Biology. 288: 502-13. PMID 16310178 DOI: 10.1016/J.Ydbio.2005.10.014  0.479
2005 McKinsey TA, Kuwahara K, Bezprozvannaya S, Olson EN. Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK. Molecular Biology of the Cell. 17: 438-47. PMID 16236793 DOI: 10.1091/Mbc.E05-07-0612  0.355
2005 Oh J, Richardson JA, Olson EN. Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation. Proceedings of the National Academy of Sciences of the United States of America. 102: 15122-7. PMID 16204380 DOI: 10.1073/Pnas.0507346102  0.414
2005 Nakagawa O, Arnold M, Nakagawa M, Hamada H, Shelton JM, Kusano H, Harris TM, Childs G, Campbell KP, Richardson JA, Nishino I, Olson EN. Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2. Genes & Development. 19: 2066-77. PMID 16140986 DOI: 10.1101/Gad.1338705  0.495
2005 Liu ZP, Wang Z, Yanagisawa H, Olson EN. Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. Developmental Cell. 9: 261-70. PMID 16054032 DOI: 10.1016/J.Devcel.2005.05.017  0.703
2005 Oh M, Rybkin II, Copeland V, Czubryt MP, Shelton JM, van Rooij E, Richardson JA, Hill JA, De Windt LJ, Bassel-Duby R, Olson EN, Rothermel BA. Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers. Molecular and Cellular Biology. 25: 6629-38. PMID 16024798 DOI: 10.1128/Mcb.25.15.6629-6638.2005  0.401
2005 Han Z, Olson EN. Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis. Development (Cambridge, England). 132: 3525-36. PMID 15975941 DOI: 10.1242/Dev.01899  0.415
2005 Chang S, Bezprozvannaya S, Li S, Olson EN. An expression screen reveals modulators of class II histone deacetylase phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 102: 8120-5. PMID 15923258 DOI: 10.1073/Pnas.0503275102  0.388
2005 Phan D, Rasmussen TL, Nakagawa O, McAnally J, Gottlieb PD, Tucker PW, Richardson JA, Bassel-Duby R, Olson EN. BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart. Development (Cambridge, England). 132: 2669-78. PMID 15890826 DOI: 10.1242/Dev.01849  0.464
2005 de Angelis L, Zhao J, Andreucci JJ, Olson EN, Cossu G, McDermott JC. Regulation of vertebrate myotome development by the p38 MAP kinase-MEF2 signaling pathway. Developmental Biology. 283: 171-9. PMID 15890335 DOI: 10.1016/J.Ydbio.2005.04.009  0.365
2005 Chen EH, Olson EN. Unveiling the mechanisms of cell-cell fusion. Science (New York, N.Y.). 308: 369-73. PMID 15831748 DOI: 10.1126/Science.1104799  0.609
2005 Kuwahara K, Barrientos T, Pipes GC, Li S, Olson EN. Muscle-specific signaling mechanism that links actin dynamics to serum response factor. Molecular and Cellular Biology. 25: 3173-81. PMID 15798203 DOI: 10.1128/Mcb.25.8.3173-3181.2005  0.479
2005 McKinsey TA, Olson EN. Toward transcriptional therapies for the failing heart: chemical screens to modulate genes. The Journal of Clinical Investigation. 115: 538-46. PMID 15765135 DOI: 10.1172/Jci24144  0.439
2005 Méjat A, Ramond F, Bassel-Duby R, Khochbin S, Olson EN, Schaeffer L. Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression. Nature Neuroscience. 8: 313-21. PMID 15711539 DOI: 10.1038/Nn1408  0.47
2005 Spencer JA, Hacker SL, Davis EC, Mecham RP, Knutsen RH, Li DY, Gerard RD, Richardson JA, Olson EN, Yanagisawa H. Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration. Proceedings of the National Academy of Sciences of the United States of America. 102: 2946-51. PMID 15710889 DOI: 10.1073/Pnas.0500058102  0.363
2005 Zhang SX, Garcia-Gras E, Wycuff DR, Marriot SJ, Kadeer N, Yu W, Olson EN, Garry DJ, Parmacek MS, Schwartz RJ. Identification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation. The Journal of Biological Chemistry. 280: 19115-26. PMID 15699019 DOI: 10.1074/Jbc.M413793200  0.469
2005 Small EM, Warkman AS, Wang DZ, Sutherland LB, Olson EN, Krieg PA. Myocardin is sufficient and necessary for cardiac gene expression in Xenopus. Development (Cambridge, England). 132: 987-97. PMID 15673566 DOI: 10.1242/Dev.01684  0.699
2005 Li S, Czubryt MP, McAnally J, Bassel-Duby R, Richardson JA, Wiebel FF, Nordheim A, Olson EN. Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 1082-7. PMID 15647354 DOI: 10.1073/Pnas.0409103102  0.471
2005 Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E. Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation Journal of Biological Chemistry. 280: 13762-13770. PMID 15623513 DOI: 10.1074/Jbc.M413396200  0.376
2005 Cao D, Wang Z, Zhang CL, Oh J, Xing W, Li S, Richardson JA, Wang DZ, Olson EN. Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Molecular and Cellular Biology. 25: 364-76. PMID 15601857 DOI: 10.1128/Mcb.25.1.364-376.2005  0.783
2005 McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN. The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development (Cambridge, England). 132: 189-201. PMID 15576406 DOI: 10.1242/Dev.01562  0.63
2004 Wang Z, Zhai W, Richardson JA, Olson EN, Meneses JJ, Firpo MT, Kang C, Skarnes WC, Tjian R. Polybromo protein BAF180 functions in mammalian cardiac chamber maturation. Genes & Development. 18: 3106-16. PMID 15601824 DOI: 10.1101/Gad.1238104  0.446
2004 Frey N, Barrientos T, Shelton JM, Frank D, Rütten H, Gehring D, Kuhn C, Lutz M, Rothermel B, Bassel-Duby R, Richardson JA, Katus HA, Hill JA, Olson EN. Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress. Nature Medicine. 10: 1336-43. PMID 15543153 DOI: 10.1038/Nm1132  0.487
2004 Vega RB, Matsuda K, Oh J, Barbosa AC, Yang X, Meadows E, McAnally J, Pomajzl C, Shelton JM, Richardson JA, Karsenty G, Olson EN. Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell. 119: 555-66. PMID 15537544 DOI: 10.1016/J.Cell.2004.10.024  0.458
2004 Kathiriya IS, King IN, Murakami M, Nakagawa M, Astle JM, Gardner KA, Gerard RD, Olson EN, Srivastava D, Nakagawa O. Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. The Journal of Biological Chemistry. 279: 54937-43. PMID 15485867 DOI: 10.1074/Jbc.M409879200  0.652
2004 Wang DZ, Olson EN. Control of smooth muscle development by the myocardin family of transcriptional coactivators. Current Opinion in Genetics & Development. 14: 558-66. PMID 15380248 DOI: 10.1016/J.Gde.2004.08.003  0.677
2004 Oh J, Wang Z, Wang DZ, Lien CL, Xing W, Olson EN. Target gene-specific modulation of myocardin activity by GATA transcription factors. Molecular and Cellular Biology. 24: 8519-28. PMID 15367672 DOI: 10.1128/Mcb.24.19.8519-8528.2004  0.767
2004 Chang S, McKinsey TA, Zhang CL, Richardson JA, Hill JA, Olson EN. Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development. Molecular and Cellular Biology. 24: 8467-76. PMID 15367668 DOI: 10.1128/Mcb.24.19.8467-8476.2004  0.401
2004 Vega RB, Harrison BC, Meadows E, Roberts CR, Papst PJ, Olson EN, McKinsey TA. Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Molecular and Cellular Biology. 24: 8374-85. PMID 15367659 DOI: 10.1128/Mcb.24.19.8374-8385.2004  0.403
2004 Han Z, Li X, Wu J, Olson EN. A myocardin-related transcription factor regulates activity of serum response factor in Drosophila Proceedings of the National Academy of Sciences of the United States of America. 101: 12567-12572. PMID 15314239 DOI: 10.1073/Pnas.0405085101  0.436
2004 Chen EH, Olson EN. Towards a molecular pathway for myoblast fusion in Drosophila. Trends in Cell Biology. 14: 452-60. PMID 15308212 DOI: 10.1016/J.Tcb.2004.07.008  0.654
2004 Masino AM, Gallardo TD, Wilcox CA, Olson EN, Williams RS, Garry DJ. Transcriptional regulation of cardiac progenitor cell populations. Circulation Research. 95: 389-97. PMID 15242968 DOI: 10.1161/01.Res.0000138302.02691.Be  0.436
2004 McKinsey TA, Olson EN. Dual roles of histone deacetylases in the control of cardiac growth. Novartis Foundation Symposium. 259: 132-41; discussion 1. PMID 15171251  0.335
2004 Olson EN. A decade of discoveries in cardiac biology. Nature Medicine. 10: 467-74. PMID 15122248 DOI: 10.1038/Nm0504-467  0.373
2004 Olson EN. Undermining the endothelium by ablation of MAPK-MEF2 signaling. The Journal of Clinical Investigation. 113: 1110-2. PMID 15085188 DOI: 10.1172/Jci21497  0.362
2004 Anderson JP, Dodou E, Heidt AB, De Val SJ, Jaehnig EJ, Greene SB, Olson EN, Black BL. HRC is a direct transcriptional target of MEF2 during cardiac, skeletal, and arterial smooth muscle development in vivo. Molecular and Cellular Biology. 24: 3757-68. PMID 15082771 DOI: 10.1128/Mcb.24.9.3757-3768.2004  0.841
2004 Frey N, Katus HA, Olson EN, Hill JA. Hypertrophy of the heart: a new therapeutic target? Circulation. 109: 1580-9. PMID 15066961 DOI: 10.1161/01.Cir.0000120390.68287.Bb  0.321
2004 McKinsey TA, Olson EN. Cardiac histone acetylation--therapeutic opportunities abound. Trends in Genetics : Tig. 20: 206-13. PMID 15041175 DOI: 10.1016/J.Tig.2004.02.002  0.422
2004 Bialek P, Kern B, Yang X, Schrock M, Sosic D, Hong N, Wu H, Yu K, Ornitz DM, Olson EN, Justice MJ, Karsenty G. A twist code determines the onset of osteoblast differentiation. Developmental Cell. 6: 423-35. PMID 15030764 DOI: 10.1016/S1534-5807(04)00058-9  0.399
2004 Wang Z, Wang DZ, Hockemeyer D, McAnally J, Nordheim A, Olson EN. Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature. 428: 185-9. PMID 15014501 DOI: 10.1038/Nature02382  0.789
2004 Cripps RM, Lovato TL, Olson EN. Positive autoregulation of the Myocyte enhancer factor-2 myogenic control gene during somatic muscle development in Drosophila. Developmental Biology. 267: 536-47. PMID 15013812 DOI: 10.1016/J.Ydbio.2003.12.004  0.504
2004 López-Rodríguez C, Antos CL, Shelton JM, Richardson JA, Lin F, Novobrantseva TI, Bronson RT, Igarashi P, Rao A, Olson EN. Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression. Proceedings of the National Academy of Sciences of the United States of America. 101: 2392-7. PMID 14983020 DOI: 10.1073/Pnas.0308703100  0.412
2004 Bush E, Fielitz J, Melvin L, Martinez-Arnold M, McKinsey TA, Plichta R, Olson EN. A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 101: 2870-5. PMID 14976250 DOI: 10.1073/Pnas.0308723101  0.454
2004 Czubryt MP, Olson EN. Balancing contractility and energy production: the role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy. Recent Progress in Hormone Research. 59: 105-24. PMID 14749499 DOI: 10.1210/Rp.59.1.105  0.403
2004 van Rooij E, Doevendans PA, Crijns HJ, Heeneman S, Lips DJ, van Bilsen M, Williams RS, Olson EN, Bassel-Duby R, Rothermel BA, De Windt LJ. MCIP1 overexpression suppresses left ventricular remodeling and sustains cardiac function after myocardial infarction. Circulation Research. 94: e18-26. PMID 14739160 DOI: 10.1161/01.Res.0000118597.54416.00  0.369
2004 Bassel-Duby R, Olson EN. Role of calcineurin in striated muscle: development, adaptation, and disease. Biochemical and Biophysical Research Communications. 311: 1133-41. PMID 14623299 DOI: 10.1016/J.Bbrc.2003.09.020  0.466
2004 Bush EW, Fielitz J, Melvin L, Arnold-Martinez M, McKinsey TA, Plichta R, Olson EN. Novel serotonergic modulators of cardiac hypertrophy Journal of Cardiac Failure. 10. DOI: 10.1016/J.Cardfail.2004.06.143  0.337
2004 Harrison BC, Vega RB, Olson EN, McKinsey TA. Protein kinases C and D target class II histone deacetylases to control pathological cardiac gene expression Journal of Cardiac Failure. 10: S57. DOI: 10.1016/J.Cardfail.2004.06.140  0.365
2004 Harrison BC, Chang S, Helmke SM, Rybkin II, Perryman B, Olson EN, McKinsey TA. A novel phospho-acceptor site controls nuclear import of histone deacetylase 9, a negative regulator of pathological cardiac hypertrophy Journal of Cardiac Failure. 10: S54. DOI: 10.1016/J.Cardfail.2004.06.128  0.371
2004 McKinsey TA, Olson EN. Dual roles of histone deacetylases in the control of cardiac growth. Novartis Foundation Symposium. 259: 132-145. DOI: 10.1002/0470862637.Ch9  0.445
2003 Wu H, Gallardo T, Olson EN, Williams RS, Shohet RV. Transcriptional analysis of mouse skeletal myofiber diversity and adaptation to endurance exercise. Journal of Muscle Research and Cell Motility. 24: 587-92. PMID 14870974 DOI: 10.1023/B:Jure.0000009968.60331.86  0.428
2003 Misra A, Haudek SB, Knuefermann P, Vallejo JG, Chen ZJ, Michael LH, Sivasubramanian N, Olson EN, Entman ML, Mann DL. Nuclear factor-kappaB protects the adult cardiac myocyte against ischemia-induced apoptosis in a murine model of acute myocardial infarction. Circulation. 108: 3075-8. PMID 14676146 DOI: 10.1161/01.Cir.0000108929.93074.0B  0.358
2003 Gaussin V, Tomlinson JE, Depre C, Engelhardt S, Antos CL, Takagi G, Hein L, Topper JN, Liggett SB, Olson EN, Lohse MJ, Vatner SF, Vatner DE. Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy. Circulation. 108: 2926-33. PMID 14623810 DOI: 10.1161/01.Cir.0000101922.18151.7B  0.419
2003 Chen EH, Pryce BA, Tzeng JA, Gonzalez GA, Olson EN. Control of myoblast fusion by a guanine nucleotide exchange factor, loner, and its effector ARF6. Cell. 114: 751-62. PMID 14505574 DOI: 10.1016/S0092-8674(03)00720-7  0.687
2003 Ryder JW, Bassel-Duby R, Olson EN, Zierath JR. Skeletal Muscle Reprogramming by Activation of Calcineurin Improves Insulin Action on Metabolic Pathways Journal of Biological Chemistry. 278: 44298-44304. PMID 12941959 DOI: 10.1074/Jbc.M304510200  0.393
2003 Olson EN, Schneider MD. Sizing up the heart: Development redux in disease Genes and Development. 17: 1937-1956. PMID 12893779 DOI: 10.1101/Gad.1110103  0.39
2003 Vega RB, Bassel-Duby R, Olson EN. Control of cardiac growth and function by calcineurin signaling. The Journal of Biological Chemistry. 278: 36981-4. PMID 12881512 DOI: 10.1074/Jbc.R300023200  0.324
2003 Li S, Wang DZ, Wang Z, Richardson JA, Olson EN. The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proceedings of the National Academy of Sciences of the United States of America. 100: 9366-70. PMID 12867591 DOI: 10.1073/Pnas.1233635100  0.765
2003 Srivastava D, Gottlieb PD, Olson EN. Molecular mechanisms of ventricular hypoplasia. Cold Spring Harbor Symposia On Quantitative Biology. 67: 121-5. PMID 12858532 DOI: 10.1101/Sqb.2002.67.121  0.583
2003 Antos CL, McKinsey TA, Dreitz M, Hollingsworth LM, Zhang CL, Schreiber K, Rindt H, Gorczynski RJ, Olson EN. Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors. The Journal of Biological Chemistry. 278: 28930-7. PMID 12761226 DOI: 10.1074/Jbc.M303113200  0.39
2003 Wang Z, Wang DZ, Pipes GC, Olson EN. Myocardin is a master regulator of smooth muscle gene expression. Proceedings of the National Academy of Sciences of the United States of America. 100: 7129-34. PMID 12756293 DOI: 10.1073/Pnas.1232341100  0.78
2003 Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, Towler DA, Ornitz DM. Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development (Cambridge, England). 130: 3063-74. PMID 12756187 DOI: 10.1242/Dev.00491  0.36
2003 Ruest LB, Dager M, Yanagisawa H, Charité J, Hammer RE, Olson EN, Yanagisawa M, Clouthier DE. dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. Developmental Biology. 257: 263-77. PMID 12729557 DOI: 10.1016/S0012-1606(03)00068-X  0.395
2003 Yoshida T, Sinha S, Dandré F, Wamhoff BR, Hoofnagle MH, Kremer BE, Wang DZ, Olson EN, Owens GK. Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circulation Research. 92: 856-64. PMID 12663482 DOI: 10.1161/01.Res.0000068405.49081.09  0.677
2003 Ivey K, Tyson B, Ukidwe P, McFadden DG, Levi G, Olson EN, Srivastava D, Wilkie TM. Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme. Developmental Biology. 255: 230-7. PMID 12648486 DOI: 10.1016/S0012-1606(02)00097-0  0.541
2003 Rybkin II, Markham DW, Yan Z, Bassel-Duby R, Williams RS, Olson EN. Conditional expression of SV40 T-antigen in mouse cardiomyocytes facilitates an inducible switch from proliferation to differentiation. The Journal of Biological Chemistry. 278: 15927-34. PMID 12590133 DOI: 10.1074/Jbc.M213102200  0.462
2003 Czubryt MP, McAnally J, Fishman GI, Olson EN. Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5. Proceedings of the National Academy of Sciences of the United States of America. 100: 1711-6. PMID 12578979 DOI: 10.1073/Pnas.0337639100  0.443
2003 Yanagisawa H, Clouthier DE, Richardson JA, Charité J, Olson EN. Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development. Development (Cambridge, England). 130: 1069-78. PMID 12571099 DOI: 10.1242/Dev.00337  0.467
2003 Šošić D, Richardson JA, Yu K, Ornitz DM, Olson EN. Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell. 112: 169-80. PMID 12553906 DOI: 10.1016/S0092-8674(03)00002-3  0.422
2003 Gajewski K, Wang J, Molkentin JD, Chen EH, Olson EN, Schulz RA. Requirement of the calcineurin subunit gene canB2 for indirect flight muscle formation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 100: 1040-5. PMID 12538857 DOI: 10.1073/Pnas.0337662100  0.766
2003 Vega RB, Rothermel BA, Weinheimer CJ, Kovacs A, Naseem RH, Bassel-Duby R, Williams RS, Olson EN. Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 100: 669-74. PMID 12515860 DOI: 10.1073/Pnas.0237225100  0.442
2003 Eliazer S, Spencer J, Ye D, Olson E, Ilaria RL. Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma. Molecular and Cellular Biology. 23: 482-92. PMID 12509448 DOI: 10.1128/Mcb.23.2.482-492.2003  0.396
2003 McKinsey TA, Zhang CL, Olson EN. Signaling chromatin to make muscle. Current Opinion in Cell Biology. 14: 763-72. PMID 12473352 DOI: 10.1016/S0955-0674(02)00389-7  0.463
2002 Wang D, Passier R, Liu ZP, Shin CH, Wang Z, Li S, Sutherland LB, Small E, Krieg PA, Olson EN. Regulation of cardiac growth and development by SRF and its cofactors. Cold Spring Harbor Symposia On Quantitative Biology. 67: 97-105. PMID 12858529 DOI: 10.1101/Sqb.2002.67.97  0.729
2002 Lu JR, Bassel-Duby R, Hawkins A, Chang P, Valdez R, Wu H, Gan L, Shelton JM, Richardson JA, Olson EN. Control of facial muscle development by MyoR and capsulin. Science (New York, N.Y.). 298: 2378-81. PMID 12493912 DOI: 10.1126/Science.1078273  0.704
2002 Wang DZ, Li S, Hockemeyer D, Sutherland L, Wang Z, Schratt G, Richardson JA, Nordheim A, Olson EN. Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 99: 14855-60. PMID 12397177 DOI: 10.1073/Pnas.222561499  0.769
2002 Naya FJ, Black BL, Wu H, Bassel-Duby R, Richardson JA, Hill JA, Olson EN. Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nature Medicine. 8: 1303-9. PMID 12379849 DOI: 10.1038/Nm789  0.705
2002 Guo L, Nakamura K, Lynch J, Opas M, Olson EN, Agellon LB, Michalak M. Cardiac-specific expression of calcineurin reverses embryonic lethality in calreticulin-deficient mouse. The Journal of Biological Chemistry. 277: 50776-9. PMID 12377773 DOI: 10.1074/Jbc.M209900200  0.399
2002 Shin CH, Liu ZP, Passier R, Zhang CL, Wang DZ, Harris TM, Yamagishi H, Richardson JA, Childs G, Olson EN. Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell. 110: 725-35. PMID 12297046 DOI: 10.1016/S0092-8674(02)00933-9  0.642
2002 Zhang CL, McKinsey TA, Olson EN. Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation. Molecular and Cellular Biology. 22: 7302-12. PMID 12242305 DOI: 10.1128/Mcb.22.20.7302-7312.2002  0.412
2002 Wu Y, Temple J, Zhang R, Dzhura I, Zhang W, Trimble R, Roden DM, Passier R, Olson EN, Colbran RJ, Anderson ME. Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation. 106: 1288-93. PMID 12208807 DOI: 10.1161/01.Cir.0000027583.73268.E7  0.365
2002 Zhang CL, McKinsey TA, Chang S, Antos CL, Hill JA, Olson EN. Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell. 110: 479-88. PMID 12202037 DOI: 10.1016/S0092-8674(02)00861-9  0.409
2002 Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O, Michael LF, Puigserver P, Isotani E, Olson EN, Lowell BB, Bassel-Duby R, Spiegelman BM. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature. 418: 797-801. PMID 12181572 DOI: 10.1038/Nature00904  0.428
2002 Asou Y, Nifuji A, Tsuji K, Shinomiya K, Olson EN, Koopman P, Noda M. Coordinated expression of scleraxis and Sox9 genes during embryonic development of tendons and cartilage. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 827-33. PMID 12168674 DOI: 10.1016/S0736-0266(01)00169-3  0.444
2002 Logan M, Martin JF, Nagy A, Lobe C, Olson EN, Tabin CJ. Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis (New York, N.Y. : 2000). 33: 77-80. PMID 12112875 DOI: 10.1002/Gene.10092  0.564
2002 McFadden DG, Olson EN. Heart development: learning from mistakes. Current Opinion in Genetics & Development. 12: 328-35. PMID 12076677 DOI: 10.1016/S0959-437X(02)00306-4  0.358
2002 Cripps RM, Olson EN. Control of cardiac development by an evolutionarily conserved transcriptional network. Developmental Biology. 246: 14-28. PMID 12027431 DOI: 10.1006/Dbio.2002.0666  0.443
2002 Olson EN. Deconstructing the transcriptional circuitry of development. Developmental Biology. 246: 1. PMID 12027429 DOI: 10.1006/Dbio.2002.0651  0.357
2002 Wu H, Olson EN. Activation of the MEF2 transcription factor in skeletal muscles from myotonic mice. The Journal of Clinical Investigation. 109: 1327-33. PMID 12021248 DOI: 10.1172/Jci15417  0.482
2002 Arai A, Spencer JA, Olson EN. STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription. The Journal of Biological Chemistry. 277: 24453-9. PMID 11983702 DOI: 10.1074/Jbc.M202216200  0.453
2002 Crabtree GR, Olson EN. NFAT signaling: choreographing the social lives of cells. Cell. 109: S67-79. PMID 11983154 DOI: 10.1016/S0092-8674(02)00699-2  0.366
2002 Lien CL, McAnally J, Richardson JA, Olson EN. Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site Developmental Biology. 244: 257-266. PMID 11944935 DOI: 10.1006/Dbio.2002.0603  0.457
2002 Gottlieb PD, Pierce SA, Sims RJ, Yamagishi H, Weihe EK, Harriss JV, Maika SD, Kuziel WA, King HL, Olson EN, Nakagawa O, Srivastava D. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nature Genetics. 31: 25-32. PMID 11923873 DOI: 10.1038/Ng866  0.667
2002 Liu ZP, Olson EN. Suppression of proliferation and cardiomyocyte hypertrophy by CHAMP, a cardiac-specific RNA helicase. Proceedings of the National Academy of Sciences of the United States of America. 99: 2043-8. PMID 11854500 DOI: 10.1073/Pnas.261708699  0.458
2002 Frey N, Olson EN. Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins. The Journal of Biological Chemistry. 277: 13998-4004. PMID 11842093 DOI: 10.1074/Jbc.M200712200  0.428
2002 Yanagisawa H, Davis EC, Starcher BC, Ouchi T, Yanagisawa M, Richardson JA, Olson EN. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature. 415: 168-71. PMID 11805834 DOI: 10.1038/415168A  0.344
2002 McKinsey TA, Zhang CL, Olson EN. MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends in Biochemical Sciences. 27: 40-7. PMID 11796223 DOI: 10.1016/S0968-0004(01)02031-X  0.384
2002 Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, Srivastava D. The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Developmental Biology. 239: 190-203. PMID 11784028 DOI: 10.1006/Dbio.2001.0417  0.618
2002 Antos CL, McKinsey TA, Frey N, Kutschke W, McAnally J, Shelton JM, Richardson JA, Hill JA, Olson EN. Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo Proceedings of the National Academy of Sciences of the United States of America. 99: 907-912. PMID 11782539 DOI: 10.1073/Pnas.231619298  0.416
2002 Henderson JR, Brown D, Richardson JA, Olson EN, Beckerle MC. Expression of the gene encoding the LIM protein CRP2: a developmental profile. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 50: 107-11. PMID 11748300  0.307
2002 Nicol RL, Frey N, Olson EN. From the sarcomere to the nucleus: role of genetics and signaling in structural heart disease. Annual Review of Genomics and Human Genetics. 1: 179-223. PMID 11701629 DOI: 10.1146/Annurev.Genom.1.1.179  0.367
2002 Frey N, Olson EN. Modulating Cardiac Hypertrophy by Manipulating Myocardial Lipid Metabolism? Circulation. 105: 1152-1154. DOI: 10.1161/Circ.105.10.1152  0.393
2001 Lilly B, Olson EN, Beckerle MC. Identification of a CArG box-dependent enhancer within the cysteine-rich protein 1 gene that directs expression in arterial but not venous or visceral smooth muscle cells. Developmental Biology. 240: 531-47. PMID 11784081 DOI: 10.1006/Dbio.2001.0507  0.511
2001 Antos CL, Frey N, Marx SO, Reiken S, Gaburjakova M, Richardson JA, Marks AR, Olson EN. Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a. Circulation Research. 89: 997-1004. PMID 11717156 DOI: 10.1161/Hh2301.100003  0.398
2001 Charité J, McFadden DG, Merlo G, Levi G, Clouthier DE, Yanagisawa M, Richardson JA, Olson EN. Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer. Genes & Development. 15: 3039-49. PMID 11711438 DOI: 10.1101/Gad.931701  0.416
2001 Chen EH, Olson EN. Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila. Developmental Cell. 1: 705-15. PMID 11709190 DOI: 10.1016/S1534-5807(01)00084-3  0.69
2001 Wu H, Rothermel B, Kanatous S, Rosenberg P, Naya FJ, Shelton JM, Hutcheson KA, DiMaio JM, Olson EN, Bassel-Duby R, Williams RS. Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway Embo Journal. 20: 6414-6423. PMID 11707412 DOI: 10.1093/Emboj/20.22.6414  0.491
2001 McKinsey TA, Zhang CL, Olson EN. Control of muscle development by dueling HATs and HDACs. Current Opinion in Genetics & Development. 11: 497-504. PMID 11532390 DOI: 10.1016/S0959-437X(00)00224-0  0.494
2001 McKinsey TA, Zhang CL, Olson EN. Identification of a signal-responsive nuclear export sequence in class II histone deacetylases. Molecular and Cellular Biology. 21: 6312-21. PMID 11509672 DOI: 10.1128/Mcb.21.18.6312-6321.2001  0.416
2001 Wang D, Chang PS, Wang Z, Sutherland L, Richardson JA, Small E, Krieg PA, Olson EN. Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell. 105: 851-62. PMID 11439182 DOI: 10.1016/S0092-8674(01)00404-4  0.804
2001 Liu ZP, Nakagawa O, Nakagawa M, Yanagisawa H, Passier R, Richardson JA, Srivastava D, Olson EN. CHAMP, a novel cardiac-specific helicase regulated by MEF2C. Developmental Biology. 234: 497-509. PMID 11397016 DOI: 10.1006/Dbio.2001.0277  0.637
2001 Zhang CL, McKinsey TA, Olson EN. The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis. Proceedings of the National Academy of Sciences of the United States of America. 98: 7354-9. PMID 11390982 DOI: 10.1073/Pnas.131198498  0.479
2001 Nicol RL, Frey N, Pearson G, Cobb M, Richardson J, Olson EN. Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy. The Embo Journal. 20: 2757-67. PMID 11387209 DOI: 10.1093/Emboj/20.11.2757  0.432
2001 Chang PS, Li L, McAnally J, Olson EN. Muscle specificity encoded by specific serum response factor-binding sites. The Journal of Biological Chemistry. 276: 17206-12. PMID 11278806 DOI: 10.1074/Jbc.M010983200  0.497
2001 Olson EN. The path to the heart and the road not taken Science. 291: 2327-2328. PMID 11269304 DOI: 10.1126/Science.1060063  0.359
2001 Rothermel BA, McKinsey TA, Vega RB, Nicol RL, Mammen P, Yang J, Antos CL, Shelton JM, Bassel-Duby R, Olson EN, Williams RS. Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 98: 3328-33. PMID 11248078 DOI: 10.1073/Pnas.041614798  0.448
2001 Myer A, Olson EN, Klein WH. MyoD cannot compensate for the absence of myogenin during skeletal muscle differentiation in murine embryonic stem cells. Developmental Biology. 229: 340-50. PMID 11203698 DOI: 10.1006/Dbio.2000.9985  0.456
2001 Johnson J, Rhee J, Parsons SM, Brown D, Olson EN, Rawls A. The anterior/posterior polarity of somites is disrupted in paraxis-deficient mice Developmental Biology. 229: 176-187. PMID 11133162 DOI: 10.1006/Dbio.2000.9969  0.696
2001 Frey N, Olson EN. Making matters worse for a broken heart. The Journal of Clinical Investigation. 106: 1437-9. PMID 11120749 DOI: 10.1172/Jci11733  0.422
2001 McKinsey TA, Zhang CL, Olson EN. Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5. Proceedings of the National Academy of Sciences of the United States of America. 97: 14400-5. PMID 11114197 DOI: 10.1073/Pnas.260501497  0.443
2001 Yang J, Rothermel B, Vega RB, Frey N, McKinsey TA, Olson EN, Bassel-Duby R, Williams RS. Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. Circulation Research. 87: E61-8. PMID 11110780 DOI: 10.1161/01.Res.87.12.E61  0.536
2001 Zhang CL, McKinsey TA, Lu JR, Olson EN. Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor. The Journal of Biological Chemistry. 276: 35-9. PMID 11022042 DOI: 10.1074/Jbc.M007364200  0.657
2000 Frey N, Richardson JA, Olson EN. Calsarcins, a novel family of sarcomeric calcineurin-binding proteins Proceedings of the National Academy of Sciences of the United States of America. 97: 14632-14637. PMID 11114196 DOI: 10.1073/Pnas.260501097  0.478
2000 Nakagawa O, McFadden DG, Nakagawa M, Yanagisawa H, Hu T, Srivastava D, Olson EN. Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 97: 13655-60. PMID 11095750 DOI: 10.1073/Pnas.250485597  0.619
2000 McKinsey TA, Zhang CL, Lu J, Olson EN. Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature. 408: 106-11. PMID 11081517 DOI: 10.1038/35040593  0.701
2000 Frey N, McKinsey TA, Olson EN. Decoding calcium signals involved in cardiac growth and function. Nature Medicine. 6: 1221-7. PMID 11062532 DOI: 10.1038/81321  0.342
2000 Srivastava D, Olson EN. A genetic blueprint for cardiac development Nature. 407: 221-226. PMID 11001064 DOI: 10.1038/35025190  0.563
2000 Lu J, McKinsey TA, Zhang CL, Olson EN. Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases. Molecular Cell. 6: 233-44. PMID 10983972 DOI: 10.1016/S1097-2765(00)00025-3  0.697
2000 Spencer JA, Eliazer S, Ilaria RL, Richardson JA, Olson EN. Regulation of microtubule dynamics and myogenic differentiation by MURF, a striated muscle RING-finger protein. The Journal of Cell Biology. 150: 771-84. PMID 10953002 DOI: 10.1083/Jcb.150.4.771  0.426
2000 Lu J, Chang P, Richardson JA, Gan L, Weiler H, Olson EN. The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis. Proceedings of the National Academy of Sciences of the United States of America. 97: 9525-30. PMID 10944221 DOI: 10.1073/Pnas.97.17.9525  0.672
2000 Vivian JL, Olson EN, Klein WH. Thoracic skeletal defects in myogenin- and MRF4-deficient mice correlate with early defects in myotome and intercostal musculature. Developmental Biology. 224: 29-41. PMID 10898959 DOI: 10.1006/Dbio.2000.9788  0.422
2000 Olson EN, Williams RS. Calcineurin signaling and muscle remodeling. Cell. 101: 689-92. PMID 10892739 DOI: 10.1016/S0092-8674(00)80880-6  0.466
2000 Molkentin JD, Tymitz KM, Richardson JA, Olson EN. Abnormalities of the genitourinary tract in female mice lacking GATA5. Molecular and Cellular Biology. 20: 5256-60. PMID 10866681 DOI: 10.1128/Mcb.20.14.5256-5260.2000  0.567
2000 Olson EN, Williams RS. Remodeling muscles with calcineurin. Bioessays. 22: 510-519. PMID 10842305 DOI: 10.1002/(Sici)1521-1878(200006)22:6<510::Aid-Bies4>3.0.Co;2-1  0.458
2000 Passier R, Zeng H, Frey N, Naya FJ, Nicol RL, McKinsey TA, Overbeek P, Richardson JA, Grant SR, Olson EN. CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo. The Journal of Clinical Investigation. 105: 1395-406. PMID 10811847 DOI: 10.1172/Jci8551  0.47
2000 Wu H, Naya FJ, McKinsey TA, Mercer B, Shelton JM, Chin ER, Simard AR, Michel RN, Bassel-Duby R, Olson EN, Williams RS. MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type. The Embo Journal. 19: 1963-73. PMID 10790363 DOI: 10.1093/Emboj/19.9.1963  0.473
2000 Johnatty SE, Dyck JR, Michael LH, Olson EN, Abdellatif M. Identification of genes regulated during mechanical load-induced cardiac hypertrophy. Journal of Molecular and Cellular Cardiology. 32: 805-15. PMID 10775485 DOI: 10.1006/Jmcc.2000.1122  0.425
2000 Martin JF, Olson EN. Identification of a prx1 limb enhancer. Genesis (New York, N.Y. : 2000). 26: 225-9. PMID 10748458 DOI: 10.1002/(Sici)1526-968X(200004)26:4<225::Aid-Gene10>3.0.Co;2-F  0.381
2000 Lu J, McKinsey TA, Nicol RL, Olson EN. Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases. Proceedings of the National Academy of Sciences of the United States of America. 97: 4070-5. PMID 10737771 DOI: 10.1073/Pnas.080064097  0.673
2000 Passier R, Richardson JA, Olson EN. Oracle, a novel PDZ-LIM domain protein expressed in heart and skeletal muscle Mechanisms of Development. 92: 277-284. PMID 10727866 DOI: 10.1016/S0925-4773(99)00330-5  0.459
2000 Skapek SX, Jansen D, Wei TF, McDermott T, Huang W, Olson EN, Lee EY. Cloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RB. The Journal of Biological Chemistry. 275: 7212-23. PMID 10702291 DOI: 10.1074/Jbc.275.10.7212  0.414
2000 Tseng BS, Cavin ST, Booth FW, Olson EN, Marin MC, McDonnell TJ, Butler IJ. Pulmonary hypoplasia in the myogenin null mouse embryo. American Journal of Respiratory Cell and Molecular Biology. 22: 304-15. PMID 10696067 DOI: 10.1165/Ajrcmb.22.3.3708  0.321
2000 Valdez MR, Richardson JA, Klein WH, Olson EN. Failure of Myf5 to support myogenic differentiation without myogenin, MyoD, and MRF4. Developmental Biology. 219: 287-98. PMID 10694423 DOI: 10.1006/Dbio.2000.9621  0.466
2000 Yamagishi H, Olson EN, Srivastava D. The basic helix-loop-helix transcription factor, dHAND, is required for vascular development. The Journal of Clinical Investigation. 105: 261-70. PMID 10675351 DOI: 10.1172/Jci8856  0.557
2000 Naya FJ, Mercer B, Shelton J, Richardson JA, Williams RS, Olson EN. Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo. The Journal of Biological Chemistry. 275: 4545-8. PMID 10671477 DOI: 10.1074/Jbc.275.7.4545  0.447
2000 Bergwerff M, Gittenberger-de Groot AC, Wisse LJ, DeRuiter MC, Wessels A, Martin JF, Olson EN, Kern MJ. Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus. Virchows Archiv : An International Journal of Pathology. 436: 12-9. PMID 10664157 DOI: 10.1007/Pl00008193  0.372
2000 Molkentin JD, Antos C, Mercer B, Taigen T, Miano JM, Olson EN. Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart. Developmental Biology. 217: 301-9. PMID 10625555 DOI: 10.1006/Dbio.1999.9544  0.625
2000 Naya FJ, Olson E. MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation. Current Opinion in Cell Biology. 11: 683-8. PMID 10600704 DOI: 10.1016/S0955-0674(99)00036-8  0.485
2000 Nakagawa O, Nakagawa M, Richardson JA, Olson EN, Srivastava D. HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Developmental Biology. 216: 72-84. PMID 10588864 DOI: 10.1006/Dbio.1999.9454  0.637
2000 McKinsey TA, Olson EN. Cardiac hypertrophy: sorting out the circuitry. Current Opinion in Genetics & Development. 9: 267-74. PMID 10377279 DOI: 10.1016/S0959-437X(99)80040-9  0.418
1999 Yeghiazaryan K, Turhani-Schatzmann D, Labudova O, Schuller E, Olson EN, Cairns N, Lubec G. Downregulation of the transcription factor scleraxis in brain of patients with Down syndrome. Journal of Neural Transmission. Supplementum. 57: 305-14. PMID 10666685 DOI: 10.1007/978-3-7091-6380-1_21  0.305
1999 Rawls A, Wilson-Rawls J, Olson EN. Genetic regulation of somite formation. Current Topics in Developmental Biology. 47: 131-54. PMID 10595304 DOI: 10.1016/S0070-2153(08)60724-3  0.796
1999 Cripps RM, Zhao B, Olson EN. Transcription of the myogenic regulatory gene Mef2 in cardiac, somatic, and visceral muscle cell lineages is regulated by a Tinman-dependent core enhancer Developmental Biology. 215: 420-430. PMID 10545248 DOI: 10.1006/Dbio.1999.9446  0.545
1999 Musarò A, McCullagh KJ, Naya FJ, Olson EN, Rosenthal N. IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Nature. 400: 581-5. PMID 10448862 DOI: 10.1038/23060  0.501
1999 Kowal RC, Richardson JA, Miano JM, Olson EN. EVEC, a novel epidermal growth factor-like repeat-containing protein upregulated in embryonic and diseased adult vasculature. Circulation Research. 84: 1166-76. PMID 10347091 DOI: 10.1161/01.Res.84.10.1166  0.416
1999 Spencer JA, Baron MH, Olson EN. Cooperative transcriptional activation by serum response factor and the high mobility group protein SSRP1 Journal of Biological Chemistry. 274: 15686-15693. PMID 10336466 DOI: 10.1074/Jbc.274.22.15686  0.433
1999 Lu JR, McKinsey TA, Xu H, Wang DZ, Richardson JA, Olson EN. FOG-2, a heart- and brain-enriched cofactor for GATA transcription factors. Molecular and Cellular Biology. 19: 4495-502. PMID 10330188 DOI: 10.1128/Mcb.19.6.4495  0.726
1999 Zhang W, Kowal RC, Rusnak F, Sikkink RA, Olson EN, Victor RG. Failure of calcineurin inhibitors to prevent pressure-overload left ventricular hypertrophy in rats. Circulation Research. 84: 722-8. PMID 10189360 DOI: 10.1161/01.Res.84.6.722  0.333
1999 Olson EN, Molkentin JD. Prevention of cardiac hypertrophy by calcineurin inhibition: hope or hype? Circulation Research. 84: 623-32. PMID 10189350 DOI: 10.1161/01.Res.84.6.623  0.546
1999 Henderson JR, Macalma T, Brown D, Richardson JA, Olson EN, Beckerle MC. The LIM protein, CRP1, is a smooth muscle marker. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 214: 229-38. PMID 10090149 DOI: 10.1002/(Sici)1097-0177(199903)214:3<229::Aid-Aja6>3.0.Co;2-S  0.48
1999 Wilson-Rawls J, Molkentin JD, Black BL, Olson EN. Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C. Molecular and Cellular Biology. 19: 2853-62. PMID 10082551 DOI: 10.1128/Mcb.19.4.2853  0.731
1999 Vivian JL, Gan L, Olson EN, Klein WH. A hypomorphic myogenin allele reveals distinct myogenin expression levels required for viability, skeletal muscle development, and sternum formation. Developmental Biology. 208: 44-55. PMID 10075840 DOI: 10.1006/Dbio.1998.9182  0.44
1999 Lu J, Webb R, Richardson JA, Olson EN. MyoR: a muscle-restricted basic helix-loop-helix transcription factor that antagonizes the actions of MyoD. Proceedings of the National Academy of Sciences of the United States of America. 96: 552-7. PMID 9892671 DOI: 10.1073/Pnas.96.2.552  0.715
1999 Lu MF, Cheng HT, Lacy AR, Kern MJ, Argao EA, Potter SS, Olson EN, Martin JF. Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis. Developmental Biology. 205: 145-57. PMID 9882503 DOI: 10.1006/Dbio.1998.9116  0.396
1999 Zhao M, New L, Kravchenko VV, Kato Y, Gram H, di Padova F, Olson EN, Ulevitch RJ, Han J. Regulation of the MEF2 family of transcription factors by p38. Molecular and Cellular Biology. 19: 21-30. PMID 9858528 DOI: 10.1128/Mcb.19.1.21  0.383
1999 Cotte N, Redfern CH, Mikus P, Salomonis N, Degtyarev MY, Coward PS, Kwa A, Shioi T, Shah N, McKinsey T, Olson E, Izumo S, Warrington J, Baker AJ, Conklin BR. A critical period of vulnerability to hyperactive Gq signaling revealed by inducible and heart-specific expression of Gq∗ in transgenic mice Journal of Cardiac Failure. 5: 12. DOI: 10.1016/S1071-9164(99)91387-8  0.309
1999 Vivian JL, Gan L, Olson EN, Klein WH. A Hypomorphic Myogenin Allele Reveals Distinct Myogenin Expression Levels Required for Viability, Skeletal Muscle Development, and Sternum Formation Developmental Biology. 210: 513. DOI: 10.1006/Dbio.1999.9305  0.419
1998 Black BL, Olson EN. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annual Review of Cell and Developmental Biology. 14: 167-96. PMID 9891782 DOI: 10.1146/Annurev.Cellbio.14.1.167  0.724
1998 Cripps RM, Olson EN. Twist is required for muscle template splitting during adult Drosophila myogenesis Developmental Biology. 203: 106-115. PMID 9806776 DOI: 10.1006/Dbio.1998.9040  0.451
1998 Lin Q, Lu J, Yanagisawa H, Webb R, Lyons GE, Richardson JA, Olson EN. Requirement of the MADS-box transcription factor MEF2C for vascular development. Development (Cambridge, England). 125: 4565-74. PMID 9778514  0.625
1998 Olson EN, Klein WH. Muscle minus myoD. Developmental Biology. 202: 153-6. PMID 9769168 DOI: 10.1006/Dbio.1998.9020  0.374
1998 Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD. Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science (New York, N.Y.). 281: 1690-3. PMID 9733519 DOI: 10.1126/Science.281.5383.1690  0.542
1998 Chin ER, Olson EN, Richardson JA, Yang Q, Humphries C, Shelton JM, Wu H, Zhu W, Bassel-Duby R, Williams RS. A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. Genes & Development. 12: 2499-509. PMID 9716403 DOI: 10.1101/Gad.12.16.2499  0.445
1998 Kawa-uchi T, Nifuji A, Mataga N, Olson EN, Bonaventure J, Shinomiya K, Liu Y, Noda M. Fibroblast growth factor downregulates expression of a basic helix-loop-helix-type transcription factor, scleraxis, in a chondrocyte-like cell line, TC6. Journal of Cellular Biochemistry. 70: 468-77. PMID 9712145 DOI: 10.1002/(Sici)1097-4644(19980915)70:4<468::Aid-Jcb4>3.0.Co;2-H  0.367
1998 Damm C, Wolk A, Buttgereit D, Löher K, Wagner E, Lilly B, Olson EN, Hasenpusch-Theil K, Renkawitz-Pohl R. Independent regulatory elements in the upstream region of the Drosophila beta 3 tubulin gene (beta Tub60D) guide expression in the dorsal vessel and the somatic muscles. Developmental Biology. 199: 138-49. PMID 9676198 DOI: 10.1006/Dbio.1998.8916  0.382
1998 Charng MJ, Frenkel PA, Lin Q, Yamada M, Schwartz RJ, Olson EN, Overbeek P, Schneider MD, Yumada M. A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice. Developmental Biology. 199: 72-9. PMID 9676193 DOI: 10.1006/Dbio.1998.8905  0.417
1998 Thomas T, Yamagishi H, Overbeek PA, Olson EN, Srivastava D. The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness. Developmental Biology. 196: 228-36. PMID 9576835 DOI: 10.1006/Dbio.1998.8849  0.582
1998 Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 93: 215-28. PMID 9568714 DOI: 10.1016/S0092-8674(00)81573-1  0.741
1998 Lu J, Richardson JA, Olson EN. Capsulin: A novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs Mechanisms of Development. 73: 23-32. PMID 9545521 DOI: 10.1016/S0925-4773(98)00030-6  0.703
1998 Zilberman A, Dave V, Miano J, Olson EN, Periasamy M. Evolutionarily conserved promoter region containing CArG*-like elements is crucial for smooth muscle myosin heavy chain gene expression. Circulation Research. 82: 566-75. PMID 9529161 DOI: 10.1161/01.Res.82.5.566  0.491
1998 Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nature Genetics. 18: 266-70. PMID 9500550 DOI: 10.1038/Ng0398-266  0.752
1998 Cripps RM, Black BL, Zhao B, Lien CL, Schulz RA, Olson EN. The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis. Genes & Development. 12: 422-34. PMID 9450935 DOI: 10.1101/Gad.12.3.422  0.711
1998 Katoh Y, Molkentin JD, Dave V, Olson EN, Periasamy M. MEF2B is a component of a smooth muscle-specific complex that binds an A/T-rich element important for smooth muscle myosin heavy chain gene expression. The Journal of Biological Chemistry. 273: 1511-8. PMID 9430690 DOI: 10.1074/Jbc.273.3.1511  0.605
1998 Wu SL, Staudinger J, Olson EN, Rubin CS. Structure, expression, and properties of an atypical protein kinase C (PKC3) from Caenorhabditis elegans. PKC3 is required for the normal progression of embryogenesis and viability of the organism. The Journal of Biological Chemistry. 273: 1130-43. PMID 9422779 DOI: 10.1074/Jbc.273.2.1130  0.406
1998 Black BL, Molkentin JD, Olson EN. Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2. Molecular and Cellular Biology. 18: 69-77. PMID 9418854 DOI: 10.1128/Mcb.18.1.69  0.712
1998 Rao RS, Miano JM, Olson EN, Seidel CL. The A10 cell line: a model for neonatal, neointimal, or differentiated vascular smooth muscle cells? Cardiovascular Research. 36: 118-26. PMID 9415280 DOI: 10.1016/S0008-6363(97)00156-9  0.315
1998 Charng M, Frenkel PA, Lin Q, Yamada M, Schwartz RJ, Olson EN, Overbeek P, Schneider MD. A Constitutive Mutation ofALK5Disrupts Cardiac Looping and Morphogenesis in Mice Developmental Biology. 202: 315. DOI: 10.1006/Dbio.1998.9046  0.316
1997 Staudinger J, Lu J, Olson EN. Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-alpha. The Journal of Biological Chemistry. 272: 32019-24. PMID 9405395 DOI: 10.1074/Jbc.272.51.32019  0.596
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