Kurt W. Runge - Publications

Molecular Genetics Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States 
Telomeres, Biology of Aging

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Rishavy MA, Hallgren KW, Zhang H, Runge KW, Berkner KL. Exon 2 Skipping Eliminates Gamma-Glutamyl Carboxylase Activity, Indicating a Partial Splicing Defect in a Patient with Vitamin K Clotting Factor Deficiency. Journal of Thrombosis and Haemostasis : Jth. PMID 31009158 DOI: 10.1111/jth.14456  0.56
2018 Audry J, Wang J, Eisenstatt JR, Berkner KL, Runge KW. The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2). F1000research. 7: 1027. PMID 30498568 DOI: 10.12688/f1000research.15166.2  0.56
2018 Wang J, Eisenstatt JR, Audry J, Cornelius K, Shaughnessy M, Berkner KL, Runge KW. A heterochromatin domain forms gradually at a new telomere and is dynamic at stable telomeres. Molecular and Cellular Biology. PMID 29784772 DOI: 10.1128/MCB.00393-17  0.56
2018 Rishavy MA, Hallgren KW, Wilson L, Singh S, Runge KW, Berkner KL. Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase. Blood. PMID 29592891 DOI: 10.1182/blood-2017-09-804666  0.56
2018 Wang J, Zhang H, Al Shibar M, Willard B, Ray A, Runge KW. Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres. Dna Repair. 65: 26-33. PMID 29544213 DOI: 10.1016/j.dnarep.2018.03.001  0.56
2017 Runge KW, Li Y. A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining. Current Genetics. PMID 29018935 DOI: 10.1007/s00294-017-0760-1  1
2017 Li Y, Wang J, Zhou G, Lajeunesse M, Le N, Stawicki BN, Corcino YL, Berkner KL, Runge KW. Non-Homologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe. Genetics. PMID 28292918 DOI: 10.1534/genetics.117.200972  1
2016 Liu Y, Lee IJ, Sun M, Lower CA, Runge KW, Ma J, Wu JQ. Roles of the novel coiled-coil protein Rng10 in septum formation during fission yeast cytokinesis. Molecular Biology of the Cell. PMID 27385337 DOI: 10.1091/mbc.E16-03-0156  0.44
2013 Corkins ME, May M, Ehrensberger KM, Hu YM, Liu YH, Bloor SD, Jenkins B, Runge KW, Bird AJ. Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast. Proceedings of the National Academy of Sciences of the United States of America. 110: 15371-6. PMID 24003116 DOI: 10.1073/pnas.1300853110  1
2013 Rishavy MA, Hallgren KW, Wilson LA, Usubalieva A, Runge KW, Berkner KL. The vitamin K oxidoreductase is a multimer that efficiently reduces vitamin K epoxide to hydroquinone to allow vitamin K-dependent protein carboxylation. The Journal of Biological Chemistry. 288: 31556-66. PMID 23918929 DOI: 10.1074/jbc.M113.497297  1
2013 Chen BR, Li Y, Eisenstatt JR, Runge KW. Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants. Plos One. 8: e69084. PMID 23874875 DOI: 10.1371/journal.pone.0069084  1
2012 Sunder S, Greeson-Lott NT, Runge KW, Sanders SL. A new method to efficiently induce a site-specific double-strand break in the fission yeast Schizosaccharomyces pombe. Yeast (Chichester, England). 29: 275-91. PMID 22674789 DOI: 10.1002/yea.2908  1
2012 Chen BR, Hale DC, Ciolek PJ, Runge KW. Generation and analysis of a barcode-tagged insertion mutant library in the fission yeast Schizosaccharomyces pombe. Bmc Genomics. 13: 161. PMID 22554201 DOI: 10.1186/1471-2164-13-161  1
2012 Ye Y, Lee IJ, Runge KW, Wu JQ. Roles of putative Rho-GEF Gef2 in division-site positioning and contractile-ring function in fission yeast cytokinesis. Molecular Biology of the Cell. 23: 1181-95. PMID 22298427 DOI: 10.1091/mbc.E11-09-0800  1
2012 Hector RE, Ray A, Chen BR, Shtofman R, Berkner KL, Runge KW. Mec1p associates with functionally compromised telomeres. Chromosoma. 121: 277-90. PMID 22289863 DOI: 10.1007/s00412-011-0359-0  1
2012 Chen BR, Runge KW. Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities. Sub-Cellular Biochemistry. 57: 291-314. PMID 22094427 DOI: 10.1007/978-94-007-2561-4_13  1
2009 Abdallah P, Luciano P, Runge KW, Lisby M, Géli V, Gilson E, Teixeira MT. A two-step model for senescence triggered by a single critically short telomere. Nature Cell Biology. 11: 988-93. PMID 19597486 DOI: 10.1038/ncb1911  1
2009 Chen BR, Runge KW. A new Schizosaccharomyces pombe chronological lifespan assay reveals that caloric restriction promotes efficient cell cycle exit and extends longevity. Experimental Gerontology. 44: 493-502. PMID 19409973 DOI: 10.1016/j.exger.2009.04.004  1
2007 Hector RE, Shtofman RL, Ray A, Chen BR, Nyun T, Berkner KL, Runge KW. Tel1p preferentially associates with short telomeres to stimulate their elongation. Molecular Cell. 27: 851-8. PMID 17803948 DOI: 10.1016/j.molcel.2007.08.007  1
2006 Rishavy MA, Hallgren KW, Yakubenko AV, Shtofman RL, Runge KW, Berkner KL. Brønsted analysis reveals Lys218 as the carboxylase active site base that deprotonates vitamin K hydroquinone to initiate vitamin K-dependent protein carboxylation. Biochemistry. 45: 13239-48. PMID 17073445 DOI: 10.1021/bi0609523  1
2006 Hallgren KW, Qian W, Yakubenko AV, Runge KW, Berkner KL. r-VKORC1 expression in factor IX BHK cells increases the extent of factor IX carboxylation but is limited by saturation of another carboxylation component or by a shift in the rate-limiting step. Biochemistry. 45: 5587-98. PMID 16634640 DOI: 10.1021/bi051986y  1
2006 Runge KW. Telomeres and Aging in the Yeast Model System Handbook of Models For Human Aging. 191-205. DOI: 10.1016/B978-012369391-4/50018-7  1
2005 Rishavy MA, Hallgren KW, Yakubenko AV, Zuerner RL, Runge KW, Berkner KL. The vitamin K-dependent carboxylase has been acquired by Leptospira pathogens and shows altered activity that suggests a role other than protein carboxylation. The Journal of Biological Chemistry. 280: 34870-7. PMID 16061481 DOI: 10.1074/jbc.M504345200  1
2004 Berkner KL, Runge KW. The physiology of vitamin K nutriture and vitamin K-dependent protein function in atherosclerosis. Journal of Thrombosis and Haemostasis : Jth. 2: 2118-32. PMID 15613016 DOI: 10.1111/j.1538-7836.2004.00968.x  1
2004 Rishavy MA, Pudota BN, Hallgren KW, Qian W, Yakubenko AV, Song JH, Runge KW, Berkner KL. A new model for vitamin K-dependent carboxylation: the catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine. Proceedings of the National Academy of Sciences of the United States of America. 101: 13732-7. PMID 15365175 DOI: 10.1073/pnas.0404989101  1
2003 Ray A, Hector RE, Roy N, Song JH, Berkner KL, Runge KW. Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan. Nature Genetics. 33: 522-6. PMID 12640455 DOI: 10.1038/ng1132  1
2001 Ray A, Runge KW. Yeast telomerase appears to frequently copy the entire template in vivo. Nucleic Acids Research. 29: 2382-94. PMID 11376157  1
2000 Roy N, Runge KW. Two paralogs involved in transcriptional silencing that antagonistically control yeast life span. Current Biology : Cb. 10: 111-4. PMID 10662670  1
1999 Ray A, Runge KW. Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 15044-9. PMID 10611335 DOI: 10.1073/pnas.96.26.15044  1
1999 Kota RS, Runge KW. Tel2p, a regulator of yeast telomeric length in vivo, binds to single-stranded telomeric DNA in vitro. Chromosoma. 108: 278-90. PMID 10525964 DOI: 10.1007/s004120050379  1
1999 Roy N, Runge KW. The ZDS1 and ZDS2 proteins require the Sir3p component of yeast silent chromatin to enhance the stability of short linear centromeric plasmids. Chromosoma. 108: 146-61. PMID 10398844 DOI: 10.1007/s004120050364  1
1999 Ray A, Runge KW. The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction. Molecular and Cellular Biology. 19: 31-45. PMID 9858529  1
1998 Kota RS, Runge KW. The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA. Nucleic Acids Research. 26: 1528-35. PMID 9490802 DOI: 10.1093/nar/26.6.1528  1
1998 Ray A, Runge KW. The C terminus of the major yeast telomere binding protein Rap1p enhances telomere formation. Molecular and Cellular Biology. 18: 1284-95. PMID 9488443  1
1996 Runge KW, Zakian VA. TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae. Molecular and Cellular Biology. 16: 3094-105. PMID 8649421  1
1993 Runge KW, Zakian VA. Saccharomyces cerevisiae linear chromosome stability (lcs) mutants increase the loss rate of artificial and natural linear chromosomes. Chromosoma. 102: 207-17. PMID 8458255 DOI: 10.1007/BF00387735  1
1991 Runge KW, Wellinger RJ, Zakian VA. Effects of excess centromeres and excess telomeres on chromosome loss rates. Molecular and Cellular Biology. 11: 2919-28. PMID 2038311  1
1990 Zakian VA, Runge K, Wang SS. How does the end begin? Formation and maintenance of telomeres in ciliates and yeast. Trends in Genetics : Tig. 6: 12-6. PMID 2183413 DOI: 10.1016/0168-9525(90)90043-6  1
1990 Runge KW, Zakian VA. Properties of the transcriptional enhancer in Saccharomyces cerevisiae telomeres. Nucleic Acids Research. 18: 1783-7. PMID 2110655  1
1989 Runge KW, Zakian VA. Introduction of extra telomeric DNA sequences into Saccharomyces cerevisiae results in telomere elongation. Molecular and Cellular Biology. 9: 1488-97. PMID 2657397  1
1987 Cooper JA, Runge K. Avian pp60(c-src) is more active when expressed in yeast than in vertebrate fibroblasts Oncogene Research. 1: 297-310. PMID 2453017  1
1986 Runge KW, Robbins PW. A new yeast mutation in the glucosylation steps of the asparagine-linked glycosylation pathway. Formation of a novel asparagine-linked oligosaccharide containing two glucose residues. The Journal of Biological Chemistry. 261: 15582-90. PMID 3536907  1
1984 Runge KW, Huffaker TC, Robbins PW. Two yeast mutations in glucosylation steps of the asparagine glycosylation pathway. The Journal of Biological Chemistry. 259: 412-7. PMID 6423630  1
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