Michael McEachern - Publications

Genetics University of Georgia, Athens, GA, United States 

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Xu J, McEachern MJ. Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scrambling. Plos Genetics. 8: e1003017. PMID 23133400 DOI: 10.1371/journal.pgen.1003017  1
2012 Xu J, McEachern MJ. Maintenance of very long telomeres by recombination in the Kluyveromyces lactis stn1-M1 mutant involves extreme telomeric turnover, telomeric circles, and concerted telomeric amplification. Molecular and Cellular Biology. 32: 2992-3008. PMID 22645309 DOI: 10.1128/MCB.00430-12  1
2012 Hsu M, Yu EY, Sprušanský O, McEachern MJ, Lue NF. Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance. Eukaryotic Cell. 11: 932-42. PMID 22544908 DOI: 10.1128/EC.05319-11  1
2011 Basenko E, Topcu Z, McEachern MJ. Recombination can either help maintain very short telomeres or generate longer telomeres in yeast cells with weak telomerase activity. Eukaryotic Cell. 10: 1131-42. PMID 21666075 DOI: 10.1128/EC.05079-11  1
2011 Guo L, Zhang D, Wang Y, Malmberg RL, McEachern M, Cai L. TRFolder: computational prediction of novel telomerase RNA structures in yeast genomes. International Journal of Bioinformatics Research and Applications. 7: 63-81. PMID 21441097 DOI: 10.1504/IJBRA.2011.039170  1
2011 Bechard LH, Jamieson N, McEachern MJ. Recombination can cause telomere elongations as well as truncations deep within telomeres in wild-type Kluyveromyces lactis cells. Eukaryotic Cell. 10: 226-36. PMID 21148753 DOI: 10.1128/EC.00209-10  1
2010 Basenko EY, Cesare AJ, Iyer S, Griffith JD, McEachern MJ. Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination. Nucleic Acids Research. 38: 182-9. PMID 19858100 DOI: 10.1093/nar/gkp814  1
2009 Wang ZR, Guo L, Chen L, McEachern MJ. Evidence for an additional base-pairing element between the telomeric repeat and the telomerase RNA template in Kluyveromyces lactis and other yeasts. Molecular and Cellular Biology. 29: 5389-98. PMID 19687297 DOI: 10.1128/MCB.00528-09  1
2009 Bechard LH, Butuner BD, Peterson GJ, McRae W, Topcu Z, McEachern MJ. Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype. Molecular and Cellular Biology. 29: 626-39. PMID 19029249 DOI: 10.1128/MCB.00423-08  1
2008 Cesare AJ, Groff-Vindman C, Compton SA, McEachern MJ, Griffith JD. Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain. Molecular and Cellular Biology. 28: 20-9. PMID 17967889 DOI: 10.1128/MCB.01122-07  1
2007 Hsu M, McEachern MJ, Dandjinou AT, Tzfati Y, Orr E, Blackburn EH, Lue NF. Telomerase core components protect Candida telomeres from aberrant overhang accumulation. Proceedings of the National Academy of Sciences of the United States of America. 104: 11682-7. PMID 17609387 DOI: 10.1073/pnas.0700327104  1
2007 Carter SD, Iyer S, Xu J, McEachern MJ, Aström SU. The role of nonhomologous end-joining components in telomere metabolism in Kluyveromyces lactis. Genetics. 175: 1035-45. PMID 17237517 DOI: 10.1534/genetics.106.067447  1
2006 McEachern MJ, Haber JE. Break-induced replication and recombinational telomere elongation in yeast. Annual Review of Biochemistry. 75: 111-35. PMID 16756487 DOI: 10.1146/annurev.biochem.74.082803.133234  1
2006 Natarajan S, Nickles K, McEachern MJ. Screening for telomeric recombination in wild-type Kluyveromyces lactis. Fems Yeast Research. 6: 442-8. PMID 16630284 DOI: 10.1111/j.1567-1364.2005.00042.x  1
2005 Iyer S, Chadha AD, McEachern MJ. A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast. Molecular and Cellular Biology. 25: 8064-73. PMID 16135798 DOI: 10.1128/MCB.25.18.8064-8073.2005  1
2005 Groff-Vindman C, Cesare AJ, Natarajan S, Griffith JD, McEachern MJ. Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles. Molecular and Cellular Biology. 25: 4406-12. PMID 15899847 DOI: 10.1128/MCB.25.11.4406-4412.2005  1
2005 Topcu Z, Nickles K, Davis C, McEachern MJ. Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis. Proceedings of the National Academy of Sciences of the United States of America. 102: 3348-53. PMID 15713803 DOI: 10.1073/pnas.0408770102  1
2004 Nickles K, McEachern MJ. Characterization of Kluyveromyces lactis subtelomeric sequences including a distal element with strong purine/pyrimidine strand bias. Yeast (Chichester, England). 21: 813-30. PMID 15300678 DOI: 10.1002/yea.1119  1
2004 Tomaska L, McEachern MJ, Nosek J. Alternatives to telomerase: keeping linear chromosomes via telomeric circles. Febs Letters. 567: 142-6. PMID 15165907 DOI: 10.1016/j.febslet.2004.04.058  1
2004 Askree SH, Yehuda T, Smolikov S, Gurevich R, Hawk J, Coker C, Krauskopf A, Kupiec M, McEachern MJ. A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proceedings of the National Academy of Sciences of the United States of America. 101: 8658-63. PMID 15161972 DOI: 10.1073/pnas.0401263101  1
2004 Underwood DH, Carroll C, McEachern MJ. Genetic dissection of the Kluyveromyces lactis telomere and evidence for telomere capping defects in TER1 mutants with long telomeres. Eukaryotic Cell. 3: 369-84. PMID 15075267 DOI: 10.1128/EC.3.2.369-384.2004  1
2004 Underwood DH, Zinzen RP, McEachern MJ. Template requirements for telomerase translocation in Kluyveromyces lactis. Molecular and Cellular Biology. 24: 912-23. PMID 14701761 DOI: 10.1128/MCB.24.2.912-923.2004  1
2003 Natarajan S, Groff-Vindman C, McEachern MJ. Factors influencing the recombinational expansion and spread of telomeric tandem arrays in Kluyveromyces lactis. Eukaryotic Cell. 2: 1115-27. PMID 14555494 DOI: 10.1128/EC.2.5.1115-1127.2003  1
2002 Natarajan S, McEachern MJ. Recombinational telomere elongation promoted by DNA circles. Molecular and Cellular Biology. 22: 4512-21. PMID 12052861 DOI: 10.1128/MCB.22.13.4512-4521.2002  1
2002 McEachern MJ, Underwood DH, Blackburn EH. Dynamics of telomeric DNA turnover in yeast. Genetics. 160: 63-73. PMID 11805045  1
2001 Underwood DH, McEachern MJ. Totally mutant telomeres: single-step mutagenesis of tandem repeat DNA sequences. Biotechniques. 30: 934-5, 938. PMID 11355352  1
2001 McEachern MJ, Iyer S. Short telomeres in yeast are highly recombinogenic. Molecular Cell. 7: 695-704. PMID 11336694 DOI: 10.1016/S1097-2765(01)00215-5  1
2000 Blackburn EH, Chan S, Chang J, Fulton TB, Krauskopf A, McEachern M, Prescott J, Roy J, Smith C, Wang H. Molecular manifestations and molecular determinants of telomere capping. Cold Spring Harbor Symposia On Quantitative Biology. 65: 253-63. PMID 12760039  1
2000 McEachern MJ, Krauskopf A, Blackburn EH. Telomeres and their control. Annual Review of Genetics. 34: 331-358. PMID 11092831 DOI: 10.1146/annurev.genet.34.1.331  1
2000 McEachern MJ, Iyer S, Fulton TB, Blackburn EH. Telomere fusions caused by mutating the terminal region of telomeric DNA. Proceedings of the National Academy of Sciences of the United States of America. 97: 11409-14. PMID 11016977 DOI: 10.1073/pnas.210388397  1
1998 Cohn M, McEachern MJ, Blackburn EH. Telomeric sequence diversity within the genus Saccharomyces. Current Genetics. 33: 83-91. PMID 9506895 DOI: 10.1007/s002940050312  1
1997 Blackburn E, Bhattacharyya A, Gilley D, Kirk K, Krauskopf A, McEachern M, Prescott J, Ware T. The telomere and telomerase: how do they interact? Ciba Foundation Symposium. 211: 2-13; discussion 15-. PMID 9524748  1
1997 Blackburn E, Bhattacharyya A, Gilley D, Kirk K, Krauskopf A, Mceachern M, Prescott J, Ware T. Studies of telomerase action Faseb Journal. 11: A876.  1
1996 McEachern MJ, Blackburn EH. Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes & Development. 10: 1822-34. PMID 8698241  1
1995 McEachern MJ, Blackburn EH. Runaway telomere elongation caused by telomerase RNA gene mutations. Nature. 376: 403-9. PMID 7630414 DOI: 10.1038/376403a0  1
1994 McEachern MJ, Blackburn EH. A conserved sequence motif within the exceptionally diverse telomeric sequences of budding yeasts. Proceedings of the National Academy of Sciences of the United States of America. 91: 3453-7. PMID 8159768  1
1993 McEachern MJ, Hicks JB. Unusually large telomeric repeats in the yeast Candida albicans. Molecular and Cellular Biology. 13: 551-60. PMID 8417351  1
1992 Sadhu C, Hoekstra D, McEachern MJ, Reed SI, Hicks JB. A G-protein alpha subunit from asexual Candida albicans functions in the mating signal transduction pathway of Saccharomyces cerevisiae and is regulated by the a1-alpha 2 repressor. Molecular and Cellular Biology. 12: 1977-85. PMID 1569935  1
1991 Sadhu C, McEachern MJ, Rustchenko-Bulgac EP, Schmid J, Soll DR, Hicks JB. Telomeric and dispersed repeat sequences in Candida yeasts and their use in strain identification. Journal of Bacteriology. 173: 842-50. PMID 1987167  1
1991 McEachern MJ, Hicks JB. Dosage of the smallest chromosome affects both the yeast-hyphal transition and the white-opaque transition of Candida albicans WO-1. Journal of Bacteriology. 173: 7436-42. PMID 1938940  1
1990 Greener A, Filutowicz MS, McEachern MJ, Helinski DR. N-terminal truncated forms of the bifunctional pi initiation protein express negative activity on plasmid R6K replication. Molecular & General Genetics : Mgg. 224: 24-32. PMID 2277631 DOI: 10.1007/BF00259447  1
1989 McEachern MJ, Bott MA, Tooker PA, Helinski DR. Negative control of plasmid R6K replication: possible role of intermolecular coupling of replication origins. Proceedings of the National Academy of Sciences of the United States of America. 86: 7942-6. PMID 2682632  1
1987 Filutowicz M, McEachern MJ, Mukhopadhyay P, Greener A, Yang SL, Helinski DR. DNA and protein interactions in the regulation of plasmid replication. Journal of Cell Science. Supplement. 7: 15-31. PMID 3332651  1
1986 Filutowicz M, McEachern MJ, Helinski DR. Positive and negative roles of an initiator protein at an origin of replication. Proceedings of the National Academy of Sciences of the United States of America. 83: 9645-9. PMID 3540947  1
1985 McEachern MJ, Filutowicz M, Helinski DR. Mutations in direct repeat sequences and in a conserved sequence adjacent to the repeats result in a defective replication origin in plasmid R6K. Proceedings of the National Academy of Sciences of the United States of America. 82: 1480-4. PMID 3883361  1
1985 Filutowicz M, McEachern M, Greener A, Mukhopadhyay P, Uhlenhopp E, Durland R, Helinski D. Role of the pi initiation protein and direct nucleotide sequence repeats in the regulation of plasmid R6K replication. Basic Life Sciences. 30: 125-40. PMID 2990404  1
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