Year |
Citation |
Score |
2023 |
El-Khoury R, Roman M, Assi HA, Moye AL, Bryan TM, Damha MJ. Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase. Nucleic Acids Research. PMID 37742080 DOI: 10.1093/nar/gkad764 |
0.462 |
|
2022 |
Niaz A, Truong JQ, Manoleras A, Fox L, Blombery P, Vasireddy RS, Pickett HA, Curtin JA, Barbaro PM, Rodgers J, Roy J, Riley LG, Holien JK, Cohen SB, Bryan T. Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder. Blood Advances. PMID 35477117 DOI: 10.1182/bloodadvances.2022007029 |
0.319 |
|
2020 |
Bryan TM. G-Quadruplexes at Telomeres: Friend or Foe? Molecules (Basel, Switzerland). 25. PMID 32823549 DOI: 10.3390/molecules25163686 |
0.467 |
|
2020 |
Paudel BP, Moye AL, Abou Assi H, El-Khoury R, Cohen S, Holien JK, Birrento ML, Samosorn S, Intharapichai K, Tomlinson CG, Teulade-Fichou MP, González C, Beck JL, Damha MJ, van Oijen AM, ... Bryan TM, et al. A mechanism for the extension and unfolding of parallel G-quadruplexes by human telomerase at single-molecule resolution. Elife. 9. PMID 32723475 DOI: 10.7554/Elife.56428 |
0.465 |
|
2019 |
Perera ON, Sobinoff AP, Teber ET, Harman A, Maritz MF, Yang SF, Pickett HA, Cesare AJ, Arthur JW, MacKenzie KL, Bryan TM. Telomerase promotes formation of a telomere protective complex in cancer cells. Science Advances. 5: eaav4409. PMID 31616780 DOI: 10.1126/Sciadv.Aav4409 |
0.31 |
|
2019 |
Bryan TM. Mechanisms of DNA Replication and Repair: Insights from the Study of G-Quadruplexes. Molecules (Basel, Switzerland). 24. PMID 31546714 DOI: 10.3390/molecules24193439 |
0.411 |
|
2018 |
Zeraati M, Langley DB, Schofield P, Moye AL, Rouet R, Hughes WE, Bryan TM, Dinger ME, Christ D. I-motif DNA structures are formed in the nuclei of human cells. Nature Chemistry. PMID 29686376 DOI: 10.1038/S41557-018-0046-3 |
0.3 |
|
2018 |
Porreca RM, Glousker G, Awad A, Matilla Fernandez MI, Gibaud A, Naucke C, Cohen SB, Bryan TM, Tzfati Y, Draskovic I, Londoño-Vallejo A. Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension. Nucleic Acids Research. PMID 29522136 DOI: 10.1093/Nar/Gky173 |
0.336 |
|
2017 |
Zeraati M, Moye AL, Wong JW, Perera D, Cowley MJ, Christ DU, Bryan TM, Dinger ME. Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression. Scientific Reports. 7: 708. PMID 28386116 DOI: 10.1038/S41598-017-00739-Y |
0.307 |
|
2016 |
Tomlinson CG, Sasaki N, Jurczyluk J, Bryan TM, Cohen SB. Quantitative assays for measuring human telomerase activity and DNA binding properties. Methods (San Diego, Calif.). PMID 27507660 DOI: 10.1016/j.ymeth.2016.08.002 |
0.311 |
|
2016 |
Tomlinson CG, Holien JK, Mathias JA, Parker MW, Bryan TM. The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA. Biochimie. PMID 27456246 DOI: 10.1016/j.biochi.2016.07.010 |
0.366 |
|
2015 |
Moye AL, Porter KC, Cohen SB, Phan T, Zyner KG, Sasaki N, Lovrecz GO, Beck JL, Bryan TM. Telomeric G-quadruplexes are a substrate and site of localization for human telomerase. Nature Communications. 6: 7643. PMID 26158869 DOI: 10.1038/ncomms8643 |
0.428 |
|
2015 |
Birrento ML, Bryan TM, Samosorn S, Beck JL. ESI-MS Investigation of an Equilibrium between a Bimolecular Quadruplex DNA and a Duplex DNA/RNA Hybrid. Journal of the American Society For Mass Spectrometry. 26: 1165-73. PMID 25906017 DOI: 10.1007/s13361-015-1121-2 |
0.38 |
|
2015 |
Tomlinson CG, Moye AL, Holien JK, Parker MW, Cohen SB, Bryan TM. Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding. The Biochemical Journal. 465: 347-57. PMID 25365545 DOI: 10.1042/BJ20140922 |
0.346 |
|
2015 |
Moye AL, Bryan TM. Proteins that interact with DNA and RNA G-quadruplexes Biological Relevance and Therapeutic Applications of Dna and Rna Quadruplexes. 101-116. DOI: 10.4155/fseb12013.14.227 |
0.472 |
|
2012 |
Yatsunyk LA, Bryan TM, Johnson FB. G-ruption: the third international meeting on G-quadruplex and G-assembly. Biochimie. 94: 2475-83. PMID 22974982 DOI: 10.1016/j.biochi.2012.09.002 |
0.323 |
|
2012 |
Stern JL, Zyner KG, Pickett HA, Cohen SB, Bryan TM. Telomerase recruitment requires both TCAB1 and Cajal bodies independently. Molecular and Cellular Biology. 32: 2384-95. PMID 22547674 DOI: 10.1128/MCB.00379-12 |
0.342 |
|
2011 |
Bryan TM, Baumann P. G-quadruplexes: from guanine gels to chemotherapeutics. Molecular Biotechnology. 49: 198-208. PMID 21416200 DOI: 10.1007/s12033-011-9395-5 |
0.622 |
|
2011 |
Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM. Direct involvement of the TEN domain at the active site of human telomerase. Nucleic Acids Research. 39: 1774-88. PMID 21051362 DOI: 10.1093/nar/gkq1083 |
0.347 |
|
2010 |
Bryan TM, Baumann P. G-quadruplexes: from guanine gels to chemotherapeutics. Methods in Molecular Biology (Clifton, N.J.). 608: 1-16. PMID 20012412 DOI: 10.1007/978-1-59745-363-9_1 |
0.622 |
|
2008 |
Stern JL, Bryan TM. Telomerase recruitment to telomeres. Cytogenetic and Genome Research. 122: 243-54. PMID 19188693 DOI: 10.1159/000167810 |
0.321 |
|
2007 |
Bryan TM, Jarstfer MB. Interrogation of G-quadruplex-protein interactions. Methods (San Diego, Calif.). 43: 332-9. PMID 17967703 DOI: 10.1016/J.Ymeth.2007.05.001 |
0.662 |
|
2007 |
Oganesian L, Graham ME, Robinson PJ, Bryan TM. Telomerase recognizes G-quadruplex and linear DNA as distinct substrates. Biochemistry. 46: 11279-90. PMID 17877374 DOI: 10.1021/bi700993q |
0.474 |
|
2007 |
Oganesian L, Bryan TM. Physiological relevance of telomeric G-quadruplex formation: a potential drug target. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 29: 155-65. PMID 17226803 DOI: 10.1002/bies.20523 |
0.46 |
|
2006 |
Chen Y, Fender J, Legassie JD, Jarstfer MB, Bryan TM, Varani G. Structure of stem-loop IV of Tetrahymena telomerase RNA. The Embo Journal. 25: 3156-66. PMID 16778765 DOI: 10.1038/Sj.Emboj.7601195 |
0.626 |
|
2006 |
Oganesian L, Moon IK, Bryan TM, Jarstfer MB. Extension of G-quadruplex DNA by ciliate telomerase. The Embo Journal. 25: 1148-59. PMID 16511573 DOI: 10.1038/Sj.Emboj.7601006 |
0.649 |
|
2003 |
Bryan TM, Goodrich KJ, Cech TR. Tetrahymena telomerase is active as a monomer. Molecular Biology of the Cell. 14: 4794-804. PMID 13679509 DOI: 10.1091/Mbc.E03-07-0474 |
0.56 |
|
2000 |
Bryan TM, Goodrich KJ, Cech TR. Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase. Molecular Cell. 6: 493-9. PMID 10983995 DOI: 10.1016/S1097-2765(00)00048-4 |
0.553 |
|
2000 |
Bryan TM, Goodrich KJ, Cech TR. A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity. The Journal of Biological Chemistry. 275: 24199-207. PMID 10807925 DOI: 10.1074/Jbc.M003246200 |
0.559 |
|
1999 |
Bryan TM, Cech TR. Telomerase and the maintenance of chromosome ends. Current Opinion in Cell Biology. 11: 318-24. PMID 10395557 DOI: 10.1016/S0955-0674(99)80043-X |
0.584 |
|
1998 |
Bryan TM, Sperger JM, Chapman KB, Cech TR. Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax. Proceedings of the National Academy of Sciences of the United States of America. 95: 8479-84. PMID 9671703 DOI: 10.1073/Pnas.95.15.8479 |
0.632 |
|
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