51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Tomlinson CG, Sasaki N, Jurczyluk J, Bryan TM, Cohen SB. Quantitative assays for measuring human telomerase activity and DNA binding properties. Methods (San Diego, Calif.). PMID 27507660 DOI: 10.1016/j.ymeth.2016.08.002  1
2016 Tomlinson CG, Holien JK, Mathias JA, Parker MW, Bryan TM. The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA. Biochimie. PMID 27456246 DOI: 10.1016/j.biochi.2016.07.010  1
2015 Tong AS, Stern JL, Sfeir A, Kartawinata M, de Lange T, Zhu XD, Bryan TM. ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres. Cell Reports. PMID 26586433 DOI: 10.1016/J.Celrep.2015.10.041  1
2015 Moye AL, Porter KC, Cohen SB, Phan T, Zyner KG, Sasaki N, Lovrecz GO, Beck JL, Bryan TM. Telomeric G-quadruplexes are a substrate and site of localization for human telomerase. Nature Communications. 6: 7643. PMID 26158869 DOI: 10.1038/ncomms8643  1
2015 Killedar A, Stutz MD, Sobinoff AP, Tomlinson CG, Bryan TM, Beesley J, Chenevix-Trench G, Reddel RR, Pickett HA. A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase. Plos Genetics. 11: e1005286. PMID 26053551 DOI: 10.1371/journal.pgen.1005286  1
2015 Birrento ML, Bryan TM, Samosorn S, Beck JL. ESI-MS Investigation of an Equilibrium between a Bimolecular Quadruplex DNA and a Duplex DNA/RNA Hybrid. Journal of the American Society For Mass Spectrometry. 26: 1165-73. PMID 25906017 DOI: 10.1007/s13361-015-1121-2  1
2015 Tomlinson CG, Moye AL, Holien JK, Parker MW, Cohen SB, Bryan TM. Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding. The Biochemical Journal. 465: 347-57. PMID 25365545 DOI: 10.1042/BJ20140922  1
2015 Moye AL, Bryan TM. Proteins that interact with DNA and RNA G-quadruplexes Biological Relevance and Therapeutic Applications of Dna and Rna Quadruplexes. 101-116. DOI: 10.4155/fseb12013.14.227  1
2014 Guo Y, Kartawinata M, Li J, Pickett HA, Teo J, Kilo T, Barbaro PM, Keating B, Chen Y, Tian L, Al-Odaib A, Reddel RR, Christodoulou J, Xu X, Hakonarson H, ... Bryan TM, et al. Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1. Blood. 124: 2767-74. PMID 25205116 DOI: 10.1182/Blood-2014-08-596445  1
2013 Tomlinson CG, Cohen SB, Bryan TM. Inhibition of Telomerase. Promise, Progress, and Potential Pitfalls Cancer Drug Design and Discovery: Second Edition. 491-527. DOI: 10.1016/B978-0-12-396521-9.00017-6  1
2012 Conomos D, Stutz MD, Hills M, Neumann AA, Bryan TM, Reddel RR, Pickett HA. Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells. The Journal of Cell Biology. 199: 893-906. PMID 23229897 DOI: 10.1083/jcb.201207189  1
2012 Yatsunyk LA, Bryan TM, Johnson FB. G-ruption: the third international meeting on G-quadruplex and G-assembly. Biochimie. 94: 2475-83. PMID 22974982 DOI: 10.1016/j.biochi.2012.09.002  1
2012 Stern JL, Zyner KG, Pickett HA, Cohen SB, Bryan TM. Telomerase recruitment requires both TCAB1 and Cajal bodies independently. Molecular and Cellular Biology. 32: 2384-95. PMID 22547674 DOI: 10.1128/MCB.00379-12  1
2011 Bryan TM, Baumann P. G-quadruplexes: from guanine gels to chemotherapeutics. Molecular Biotechnology. 49: 198-208. PMID 21416200 DOI: 10.1007/s12033-011-9395-5  1
2011 Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM. Direct involvement of the TEN domain at the active site of human telomerase. Nucleic Acids Research. 39: 1774-88. PMID 21051362 DOI: 10.1093/nar/gkq1083  1
2010 Bryan TM, Baumann P. G-quadruplexes: from guanine gels to chemotherapeutics. Methods in Molecular Biology (Clifton, N.J.). 608: 1-16. PMID 20012412 DOI: 10.1007/978-1-59745-363-9_1  1
2008 Stern JL, Bryan TM. Telomerase recruitment to telomeres. Cytogenetic and Genome Research. 122: 243-54. PMID 19188693 DOI: 10.1159/000167810  1
2008 Cao Y, Bryan TM, Reddel RR. Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells. Cancer Science. 99: 1092-9. PMID 18482052 DOI: 10.1111/j.1349-7006.2008.00815.x  1
2008 Cao Y, Huschtscha LI, Nouwens AS, Pickett HA, Neumann AA, Chang AC, Toouli CD, Bryan TM, Reddel RR. Amplification of telomerase reverse transcriptase gene in human mammary epithelial cells with limiting telomerase RNA expression levels. Cancer Research. 68: 3115-23. PMID 18451136 DOI: 10.1158/0008-5472.CAN-07-6377  1
2008 Finger SN, Bryan TM. Multiple DNA-binding sites in Tetrahymena telomerase. Nucleic Acids Research. 36: 1260-72. PMID 18174223 DOI: 10.1093/nar/gkm866  1
2007 Bryan TM, Jarstfer MB. Interrogation of G-quadruplex-protein interactions. Methods (San Diego, Calif.). 43: 332-9. PMID 17967703 DOI: 10.1016/J.Ymeth.2007.05.001  1
2007 Oganesian L, Graham ME, Robinson PJ, Bryan TM. Telomerase recognizes G-quadruplex and linear DNA as distinct substrates. Biochemistry. 46: 11279-90. PMID 17877374 DOI: 10.1021/bi700993q  1
2007 Oganesian L, Bryan TM. Physiological relevance of telomeric G-quadruplex formation: a potential drug target. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 29: 155-65. PMID 17226803 DOI: 10.1002/bies.20523  1
2006 Chen Y, Fender J, Legassie JD, Jarstfer MB, Bryan TM, Varani G. Structure of stem-loop IV of Tetrahymena telomerase RNA. The Embo Journal. 25: 3156-66. PMID 16778765 DOI: 10.1038/Sj.Emboj.7601195  1
2006 Oganesian L, Moon IK, Bryan TM, Jarstfer MB. Extension of G-quadruplex DNA by ciliate telomerase. The Embo Journal. 25: 1148-59. PMID 16511573 DOI: 10.1038/Sj.Emboj.7601006  1
2003 Bryan TM, Goodrich KJ, Cech TR. Tetrahymena telomerase is active as a monomer. Molecular Biology of the Cell. 14: 4794-804. PMID 13679509 DOI: 10.1091/Mbc.E03-07-0474  1
2003 Reddel RR, Bryan TM. Alternative lengthening of telomeres: dangerous road less travelled. Lancet (London, England). 361: 1840-1. PMID 12788566 DOI: 10.1016/S0140-6736(03)13538-6  1
2001 Reddel RR, Bryan TM, Colgin LM, Perrem KT, Yeager TR. Alternative lengthening of telomeres in human cells. Radiation Research. 155: 194-200. PMID 11121234  1
2000 Bryan TM, Goodrich KJ, Cech TR. Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase. Molecular Cell. 6: 493-9. PMID 10983995 DOI: 10.1016/S1097-2765(00)00048-4  1
2000 Bryan TM, Goodrich KJ, Cech TR. A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity. The Journal of Biological Chemistry. 275: 24199-207. PMID 10807925 DOI: 10.1074/Jbc.M003246200  1
1999 Bryan TM, Cech TR. Telomerase and the maintenance of chromosome ends. Current Opinion in Cell Biology. 11: 318-24. PMID 10395557 DOI: 10.1016/S0955-0674(99)80043-X  1
1999 Perrem K, Bryan TM, Englezou A, Hackl T, Moy EL, Reddel RR. Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids. Oncogene. 18: 3383-90. PMID 10362359 DOI: 10.1038/sj.onc.1202752  1
1998 Bryan TM, Sperger JM, Chapman KB, Cech TR. Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax. Proceedings of the National Academy of Sciences of the United States of America. 95: 8479-84. PMID 9671703 DOI: 10.1073/Pnas.95.15.8479  1
1998 Bryan TM, Englezou A, Dunham MA, Reddel RR. Telomere length dynamics in telomerase-positive immortal human cell populations. Experimental Cell Research. 239: 370-8. PMID 9521855 DOI: 10.1006/excr.1997.3907  1
1997 Lansdorp PM, Poon S, Chavez E, Dragowska V, Zijlmans M, Bryan T, Reddel R, Egholm M, Bacchetti S, Martens U. Telomeres in the haemopoietic system Ciba Foundation Symposia. 209-222. PMID 9524760  1
1997 Reddel RR, Bryan TM, Murnane JP. Immortalized cells with no detectable telomerase activity. A review. Biochemistry. Biokhimii͡A. 62: 1254-62. PMID 9467849  1
1997 Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nature Medicine. 3: 1271-4. PMID 9359704  1
1997 Sprung CN, Bryan TM, Reddel RR, Murnane JP. Normal telomere maintenance in immortal ataxia telangiectasia cell lines. Mutation Research. 379: 177-84. PMID 9357546 DOI: 10.1016/S0027-5107(97)00119-X  1
1997 Bryan TM, Reddel RR. Telomere dynamics and telomerase activity in in vitro immortalised human cells. European Journal of Cancer (Oxford, England : 1990). 33: 767-73. PMID 9282115 DOI: 10.1016/S0959-8049(97)00065-8  1
1997 Bryan TM, Marusic L, Bacchetti S, Namba M, Reddel RR. The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit. Human Molecular Genetics. 6: 921-6. PMID 9175740 DOI: 10.1093/hmg/6.6.921  1
1996 Noble JR, Rogan EM, Neumann AA, Maclean K, Bryan TM, Reddel RR. Association of extended in vitro proliferative potential with loss of p16INK4 expression. Oncogene. 13: 1259-68. PMID 8808700  1
1996 Reddel RR, Bryan TM, Rogan EM, Noble JR, Maclean K, Whitaker NJ, Chang ACM. Genetic changes during immortalization of human cells Radiation Oncology Investigations. 3: 299-306.  1
1995 Whitaker NJ, Bryan TM, Bonnefin P, Chang AC, Musgrove EA, Braithwaite AW, Reddel RR. Involvement of RB-1, p53, p16INK4 and telomerase in immortalisation of human cells. Oncogene. 11: 971-6. PMID 7675456  1
1995 Rogan EM, Bryan TM, Hukku B, Maclean K, Chang AC, Moy EL, Englezou A, Warneford SG, Dalla-Pozza L, Reddel RR. Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts. Molecular and Cellular Biology. 15: 4745-53. PMID 7651392  1
1995 Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR. Telomere elongation in immortal human cells without detectable telomerase activity. The Embo Journal. 14: 4240-8. PMID 7556065  1
1994 Bryan TM, Reddel RR. SV40-induced immortalization of human cells. Critical Reviews in Oncogenesis. 5: 331-57. PMID 7711112  1
1993 Smith KJ, Johnson KA, Bryan TM, Hill DE, Markowitz S, Willson JK, Paraskeva C, Petersen GM, Hamilton SR, Vogelstein B. The APC gene product in normal and tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 2846-50. PMID 8385345 DOI: 10.1073/Pnas.90.7.2846  1
1992 Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B, Kinzler KW. APC mutations occur early during colorectal tumorigenesis. Nature. 359: 235-7. PMID 1528264 DOI: 10.1038/359235A0  1
1991 Kinzler KW, Nilbert MC, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hamilton SR, Hedge P, Markham A. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science (New York, N.Y.). 251: 1366-70. PMID 1848370 DOI: 10.1126/Science.1848370  1
1991 Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P, Markham A, Krush AJ, Petersen G, Hamilton SR, Nilbert MC, ... ... Bryan TM, et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients Science. 253: 665-669. PMID 1651563 DOI: 10.1126/Science.1651563  1
1991 Kinzler KW, Nilbert MC, Su LK, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D. Identification of FAP locus genes from chromosome 5q21. Science (New York, N.Y.). 253: 661-5. PMID 1651562 DOI: 10.1126/Science.1651562  1
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