Christopher M. Counter - Publications

Duke Medical School, Durham, NC, United States 

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Schook LB, Collares TV, Hu W, Liang Y, Rodrigues FM, Rund LA, Schachtschneider KM, Seixas FK, Singh K, Wells KD, Walters EM, Prather RS, Counter CM. A Genetic Porcine Model of Cancer. Plos One. 10: e0128864. PMID 26132737 DOI: 10.1371/journal.pone.0128864  1
2015 Huang L, Counter CM. Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S. Plos One. 10: e0123918. PMID 25902334 DOI: 10.1371/journal.pone.0123918  1
2015 Kashatus JA, Nascimento A, Myers LJ, Sher A, Byrne FL, Hoehn KL, Counter CM, Kashatus DF. Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth. Molecular Cell. 57: 537-51. PMID 25658205 DOI: 10.1016/j.molcel.2015.01.002  1
2015 Pershing NL, Lampson BL, Belsky JA, Kaltenbrun E, MacAlpine DM, Counter CM. Rare codons capacitate Kras-driven de novo tumorigenesis. The Journal of Clinical Investigation. 125: 222-33. PMID 25437878 DOI: 10.1172/JCI77627  1
2014 Huang L, Carney J, Cardona DM, Counter CM. Decreased tumorigenesis in mice with a Kras point mutation at C118. Nature Communications. 5: 5410. PMID 25394415 DOI: 10.1038/ncomms6410  1
2014 Brady DC, Crowe MS, Turski ML, Hobbs GA, Yao X, Chaikuad A, Knapp S, Xiao K, Campbell SL, Thiele DJ, Counter CM. Copper is required for oncogenic BRAF signalling and tumorigenesis. Nature. 509: 492-6. PMID 24717435 DOI: 10.1038/nature13180  1
2013 Yang S, Counter CM. Cell cycle regulated phosphorylation of the telomere-associated protein TIN2. Plos One. 8: e71697. PMID 23977114 DOI: 10.1371/journal.pone.0071697  1
2013 Lampson BL, Pershing NL, Prinz JA, Lacsina JR, Marzluff WF, Nicchitta CV, MacAlpine DM, Counter CM. Rare codons regulate KRas oncogenesis. Current Biology : Cb. 23: 70-5. PMID 23246410 DOI: 10.1016/j.cub.2012.11.031  1
2012 Stringer JR, Counter CM. Snm1B interacts with PSF2. Plos One. 7: e49626. PMID 23189151 DOI: 10.1371/journal.pone.0049626  1
2012 Lampson BL, Kendall SD, Ancrile BB, Morrison MM, Shealy MJ, Barrientos KS, Crowe MS, Kashatus DF, White RR, Gurley SB, Cardona DM, Counter CM. Targeting eNOS in pancreatic cancer. Cancer Research. 72: 4472-82. PMID 22738914 DOI: 10.1158/0008-5472.CAN-12-0057  1
2012 Yonekawa T, Yang S, Counter CM. PinX1 localizes to telomeres and stabilizes TRF1 at mitosis. Molecular and Cellular Biology. 32: 1387-95. PMID 22331467 DOI: 10.1128/MCB.05641-11  1
2012 Turski ML, Brady DC, Kim HJ, Kim BE, Nose Y, Counter CM, Winge DR, Thiele DJ. A novel role for copper in Ras/mitogen-activated protein kinase signaling. Molecular and Cellular Biology. 32: 1284-95. PMID 22290441 DOI: 10.1128/MCB.05722-11  1
2011 Kashatus DF, Lim KH, Brady DC, Pershing NL, Cox AD, Counter CM. RALA and RALBP1 regulate mitochondrial fission at mitosis. Nature Cell Biology. 13: 1108-15. PMID 21822277 DOI: 10.1038/ncb2310  1
2011 Kashatus DF, Counter CM. Breaking up is hard to do RalA, mitochondrial fission and cancer Small Gtpases. 2.  1
2010 Zipfel PA, Brady DC, Kashatus DF, Ancrile BD, Tyler DS, Counter CM. Ral activation promotes melanomagenesis. Oncogene. 29: 4859-64. PMID 20562921 DOI: 10.1038/onc.2010.224  1
2010 Watson CJ, Roberts R, Wright KA, Greenberg DC, Rous BA, Brown CH, Counter C, Collett D, Bradley JA. How safe is it to transplant organs from deceased donors with primary intracranial malignancy? An analysis of UK Registry data. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10: 1437-44. PMID 20486904 DOI: 10.1111/j.1600-6143.2010.03130.x  1
2010 Vignola MJ, Kashatus DF, Taylor GA, Counter CM, Valdivia RH. cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis. The Journal of Biological Chemistry. 285: 21625-35. PMID 20452986 DOI: 10.1074/jbc.M110.103010  1
2010 Issaq SH, Lim KH, Counter CM. Sec5 and Exo84 foster oncogenic ras-mediated tumorigenesis. Molecular Cancer Research : McR. 8: 223-31. PMID 20145037 DOI: 10.1158/1541-7786.MCR-09-0189  1
2010 Lim KH, Brady DC, Kashatus DF, Ancrile BB, Der CJ, Cox AD, Counter CM. Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA. Molecular and Cellular Biology. 30: 508-23. PMID 19901077 DOI: 10.1128/MCB.00916-08  1
2010 Petersen TH, Hitchcock T, Muto A, Calle EA, Zhao L, Gong Z, Gui L, Dardik A, Bowles DE, Counter CM, Niklason LE. Utility of telomerase-pot1 fusion protein in vascular tissue engineering. Cell Transplantation. 19: 79-87. PMID 19878625 DOI: 10.3727/096368909X478650  1
2009 O'Hayer KM, Brady DC, Counter CM. ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis. Carcinogenesis. 30: 1841-7. PMID 19805574 DOI: 10.1093/carcin/bgp198  1
2009 Kendellen MF, Barrientos KS, Counter CM. POT1 association with TRF2 regulates telomere length. Molecular and Cellular Biology. 29: 5611-9. PMID 19651898 DOI: 10.1128/MCB.00286-09  1
2008 Naini S, Etheridge KT, Adam SJ, Qualman SJ, Bentley RC, Counter CM, Linardic CM. Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma. Cancer Research. 68: 9583-8. PMID 19047133 DOI: 10.1158/0008-5472.CAN-07-6178  1
2008 Schook LB, Kuzmuk K, Adam S, Rund L, Chen K, Rogatcheva M, Mazur M, Pollock C, Counter C. DNA-based animal models of human disease: From genotype to phenotype Developments in Biologicals. 132: 15-25. PMID 18817282  1
2008 Lee YS, Lim KH, Guo X, Kawaguchi Y, Gao Y, Barrientos T, Ordentlich P, Wang XF, Counter CM, Yao TP. The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis. Cancer Research. 68: 7561-9. PMID 18794144 DOI: 10.1158/0008-5472.CAN-08-0188  1
2008 Freibaum BD, Counter CM. The protein hSnm1B is stabilized when bound to the telomere-binding protein TRF2. The Journal of Biological Chemistry. 283: 23671-6. PMID 18593705 DOI: 10.1074/jbc.M800388200  1
2008 Tomlinson RL, Abreu EB, Ziegler T, Ly H, Counter CM, Terns RM, Terns MP. Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells. Molecular Biology of the Cell. 19: 3793-800. PMID 18562689 DOI: 10.1091/mbc.E08-02-0184  1
2008 Barrientos KS, Kendellen MF, Freibaum BD, Armbruster BN, Etheridge KT, Counter CM. Distinct functions of POT1 at telomeres. Molecular and Cellular Biology. 28: 5251-64. PMID 18519588 DOI: 10.1128/MCB.00048-08  1
2008 Linardic CM, Counter CM. Genetic modeling of Ras-induced human rhabdomyosarcoma. Methods in Enzymology. 438: 419-27. PMID 18413264 DOI: 10.1016/S0076-6879(07)38028-2  1
2008 Adam SJ, Counter CM. A method to generate genetically defined tumors in pigs. Methods in Enzymology. 439: 39-51. PMID 18374155 DOI: 10.1016/S0076-6879(07)00404-1  1
2008 Lim KH, Ancrile BB, Kashatus DF, Counter CM. Tumour maintenance is mediated by eNOS. Nature. 452: 646-9. PMID 18344980 DOI: 10.1038/nature06778  1
2008 Ancrile BB, O'Hayer KM, Counter CM. Oncogenic ras-induced expression of cytokines: a new target of anti-cancer therapeutics. Molecular Interventions. 8: 22-7. PMID 18332481 DOI: 10.1124/mi.8.1.6  1
2008 Etheridge KT, Compton SA, Barrientos KS, Ozgur S, Griffith JD, Counter CM. Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation. The Journal of Biological Chemistry. 283: 6935-41. PMID 18178559 DOI: 10.1074/jbc.M708711200  1
2007 Rogatcheva MB, Fritz KL, Rund LA, Pollock CB, Beever JE, Counter CM, Schook LB. Characterization of the porcine ATM gene: towards the generation of a novel non-murine animal model for Ataxia-Telangiectasia. Gene. 405: 27-35. PMID 17933474 DOI: 10.1016/j.gene.2007.08.014  1
2007 Ancrile B, Lim KH, Counter CM. Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. Genes & Development. 21: 1714-9. PMID 17639077 DOI: 10.1101/gad.1549407  1
2007 Linardic CM, Naini S, Herndon JE, Kesserwan C, Qualman SJ, Counter CM. The PAX3-FKHR fusion gene of rhabdomyosarcoma cooperates with loss of p16INK4A to promote bypass of cellular senescence. Cancer Research. 67: 6691-9. PMID 17638879 DOI: 10.1158/0008-5472.CAN-06-3210  1
2007 Adam SJ, Rund LA, Kuzmuk KN, Zachary JF, Schook LB, Counter CM. Genetic induction of tumorigenesis in swine. Oncogene. 26: 1038-45. PMID 16964292 DOI: 10.1038/sj.onc.1209892  1
2007 Banik SSR, Counter CM. From bread to bedside: What budding yeast has taught us about the immortalization of cancer cells Yeast as a Tool in Cancer Research. 123-139. DOI: 10.1007/978-1-4020-5963-6_5  1
2006 Lim KH, O'Hayer K, Adam SJ, Kendall SD, Campbell PM, Der CJ, Counter CM. Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. Current Biology : Cb. 16: 2385-94. PMID 17174914 DOI: 10.1016/j.cub.2006.10.023  1
2006 O'Hayer KM, Counter CM. A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro. Methods in Enzymology. 407: 637-47. PMID 16757358 DOI: 10.1016/S0076-6879(05)07050-3  1
2006 Baines AT, Lim KH, Shields JM, Lambert JM, Counter CM, Der CJ, Cox AD. Use of retrovirus expression of interfering RNA to determine the contribution of activated K-Ras and ras effector expression to human tumor cell growth. Methods in Enzymology. 407: 556-74. PMID 16757353 DOI: 10.1016/S0076-6879(05)07045-X  1
2006 Kendall SD, Adam SJ, Counter CM. Genetically engineered human cancer models utilizing mammalian transgene expression. Cell Cycle (Georgetown, Tex.). 5: 1074-9. PMID 16687931  1
2006 Freibaum BD, Counter CM. hSnm1B is a novel telomere-associated protein. The Journal of Biological Chemistry. 281: 15033-6. PMID 16606622 DOI: 10.1074/jbc.C600038200  1
2005 Lim KH, Counter CM. Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance. Cancer Cell. 8: 381-92. PMID 16286246 DOI: 10.1016/j.ccr.2005.10.014  1
2005 Kendall SD, Linardic CM, Adam SJ, Counter CM. A network of genetic events sufficient to convert normal human cells to a tumorigenic state. Cancer Research. 65: 9824-8. PMID 16267004 DOI: 10.1158/0008-5472.CAN-05-1543  1
2005 Kassem M, Burns J, Abd-Allah B, Torensma R, Niklason LE, Counter CM. Blood vessels engineered from human cells [3] (multiple letters) Lancet. 366: 891-893. PMID 16154007 DOI: 10.1016/S0140-6736(05)67311-4  1
2005 Poh M, Boyer M, Solan A, Dahl SL, Pedrotty D, Banik SS, McKee JA, Klinger RY, Counter CM, Niklason LE. Blood vessels engineered from human cells. Lancet. 365: 2122-4. PMID 15964449 DOI: 10.1016/S0140-6736(05)66735-9  1
2005 Lim KH, Baines AT, Fiordalisi JJ, Shipitsin M, Feig LA, Cox AD, Der CJ, Counter CM. Activation of RalA is critical for Ras-induced tumorigenesis of human cells. Cancer Cell. 7: 533-45. PMID 15950903 DOI: 10.1016/j.ccr.2005.04.030  1
2005 Linardic CM, Downie DL, Qualman S, Bentley RC, Counter CM. Genetic modeling of human rhabdomyosarcoma. Cancer Research. 65: 4490-5. PMID 15930263 DOI: 10.1158/0008-5472.CAN-04-3194  1
2004 Rogatcheva MM, Rund LA, Swanson KS, Marron BM, Beever JE, Counter CM, Schook LB. Creating porcine biomedical models through recombineering. Comparative and Functional Genomics. 5: 262-7. PMID 18629152 DOI: 10.1002/cfg.404  1
2004 Veldman T, Etheridge KT, Counter CM. Loss of hPot1 function leads to telomere instability and a cut-like phenotype. Current Biology : Cb. 14: 2264-70. PMID 15620654 DOI: 10.1016/j.cub.2004.12.031  1
2004 Swanson KS, Mazur MJ, Vashisht K, Rund LA, Beever JE, Counter CM, Schook LB. Genomics and clinical medicine: rationale for creating and effectively evaluating animal models. Experimental Biology and Medicine (Maywood, N.J.). 229: 866-75. PMID 15388881  1
2004 Banik SS, Counter CM. Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR. The Journal of Biological Chemistry. 279: 51745-8. PMID 15381700 DOI: 10.1074/jbc.M408131200  1
2004 Lim KH, Counter CM. Leveling the playing field. Molecular Cell. 15: 491-2. PMID 15327763 DOI: 10.1016/j.molcel.2004.08.014  1
2004 Armbruster BN, Linardic CM, Veldman T, Bansal NP, Downie DL, Counter CM. Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1. Molecular and Cellular Biology. 24: 3552-61. PMID 15060173 DOI: 10.1128/MCB.24.8.3552-3561.2004  1
2004 Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G, Hahn WC, Stukenberg PT, Shenolikar S, Uchida T, Counter CM, Nevins JR, Means AR, Sears R. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nature Cell Biology. 6: 308-18. PMID 15048125 DOI: 10.1038/ncb1110  1
2003 Guo C, Armbruster BN, Price DT, Counter CM. In vivo regulation of hTERT expression and telomerase activity by androgen. The Journal of Urology. 170: 615-8. PMID 12853842 DOI: 10.1097/01.ju.0000074653.22766.c8  1
2003 McKee JA, Banik SS, Boyer MJ, Hamad NM, Lawson JH, Niklason LE, Counter CM. Human arteries engineered in vitro. Embo Reports. 4: 633-8. PMID 12776184 DOI: 10.1038/sj.embor.embor847  1
2003 Counter CM, Press W, Compton CC. Telomere shortening in cultured autografts of patients with burns. Lancet (London, England). 361: 1345-6. PMID 12711471 DOI: 10.1016/S0140-6736(03)13042-5  1
2003 Armbruster BN, Etheridge KT, Broccoli D, Counter CM. Putative telomere-recruiting domain in the catalytic subunit of human telomerase. Molecular and Cellular Biology. 23: 3237-46. PMID 12697823 DOI: 10.1128/MCB.23.9.3237-3246.2003  1
2003 Rich JN, Shi Q, Hjelmeland M, Cummings TJ, Kuan CT, Bigner DD, Counter CM, Wang XF. Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. The Journal of Biological Chemistry. 278: 15951-7. PMID 12590137 DOI: 10.1074/jbc.M211498200  1
2002 Hamad NM, Banik SS, Counter CM. Mutational analysis defines a minimum level of telomerase activity required for tumourigenic growth of human cells. Oncogene. 21: 7121-5. PMID 12370834 DOI: 10.1038/sj.onc.1205860  1
2002 Hamad NM, Elconin JH, Karnoub AE, Bai W, Rich JN, Abraham RT, Der CJ, Counter CM. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes & Development. 16: 2045-57. PMID 12183360 DOI: 10.1101/gad.993902  1
2002 Banik SS, Guo C, Smith AC, Margolis SS, Richardson DA, Tirado CA, Counter CM. C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity. Molecular and Cellular Biology. 22: 6234-46. PMID 12167716 DOI: 10.1128/MCB.22.17.6234-6246.2002  1
2002 Shi S, Gronthos S, Chen S, Reddi A, Counter CM, Robey PG, Wang CY. Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nature Biotechnology. 20: 587-91. PMID 12042862 DOI: 10.1038/nbt0602-587  1
2002 Etheridge KT, Banik SS, Armbruster BN, Zhu Y, Terns RM, Terns MP, Counter CM. The nucleolar localization domain of the catalytic subunit of human telomerase. The Journal of Biological Chemistry. 277: 24764-70. PMID 11956201 DOI: 10.1074/jbc.M201227200  1
2001 Armbruster BN, Banik SS, Guo C, Smith AC, Counter CM. N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo. Molecular and Cellular Biology. 21: 7775-86. PMID 11604512 DOI: 10.1128/MCB.21.22.7775-7786.2001  1
2001 Guo C, Geverd D, Liao R, Hamad N, Counter CM, Price DT. Inhibition of telomerase is related to the life span and tumorigenicity of human prostate cancer cells. The Journal of Urology. 166: 694-8. PMID 11458119  1
2001 Rich JN, Guo C, McLendon RE, Bigner DD, Wang XF, Counter CM. A genetically tractable model of human glioma formation. Cancer Research. 61: 3556-60. PMID 11325817  1
1999 Hu PPC, Shen X, Huang D, Liu Y, Counter C, Wang XF. The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-β Journal of Biological Chemistry. 274: 35381-35387. PMID 10585406 DOI: 10.1074/jbc.274.50.35381  1
1999 Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, Weinberg RA. Creation of human tumour cells with defined genetic elements. Nature. 400: 464-8. PMID 10440377 DOI: 10.1038/22780  1
1999 Xie Y, Counter C, Alani E. Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loader Genetics. 151: 499-509. PMID 9927446  1
1998 Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA. Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proceedings of the National Academy of Sciences of the United States of America. 95: 14723-8. PMID 9843956 DOI: 10.1073/pnas.95.25.14723  1
1998 Kolquist KA, Ellisen LW, Counter CM, Meyerson M, Tan LK, Weinberg RA, Haber DA, Gerald WL. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nature Genetics. 19: 182-6. PMID 9620778 DOI: 10.1038/554  1
1998 Counter CM, Meyerson M, Eaton EN, Ellisen LW, Caddle SD, Haber DA, Weinberg RA. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene. 16: 1217-22. PMID 9528864 DOI: 10.1038/sj.onc.1201882  1
1997 Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell. 90: 785-95. PMID 9288757 DOI: 10.1016/S0092-8674(00)80538-3  1
1997 Counter CM, Meyerson M, Eaton EN, Weinberg RA. The catalytic subunit of yeast telomerase. Proceedings of the National Academy of Sciences of the United States of America. 94: 9202-7. PMID 9256460 DOI: 10.1073/pnas.94.17.9202  1
1996 Counter CM. The roles of telomeres and telomerase in cell life span. Mutation Research. 366: 45-63. PMID 8921986 DOI: 10.1016/S0165-1110(96)90006-8  1
1995 Counter CM, Gupta J, Harley CB, Leber B, Bacchetti S. Telomerase activity in normal leukocytes and in hematologic malignancies. Blood. 85: 2315-20. PMID 7727765  1
1995 Bacchetti S, Counter CM. Telomeres and telomerase in human cancer. (Review) International Journal of Oncology. 7: 423-432.  1
1994 Counter CM, Hirte HW, Bacchetti S, Harley CB. Telomerase activity in human ovarian carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 91: 2900-4. PMID 8159676  1
1994 Counter CM, Botelho FM, Wang P, Harley CB, Bacchetti S. Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. Journal of Virology. 68: 3410-4. PMID 8151802  1
1994 Harley CB, Kim NW, Prowse KR, Weinrich SL, Hirsch KS, West MD, Bacchetti S, Hirte HW, Counter CM, Greider CW. Telomerase, cell immortality, and cancer. Cold Spring Harbor Symposia On Quantitative Biology. 59: 307-15. PMID 7587082  1
1992 Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB, Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. The Embo Journal. 11: 1921-9. PMID 1582420  1
1992 Harley CB, Vaziri H, Counter CM, Allsopp RC. The telomere hypothesis of cellular aging. Experimental Gerontology. 27: 375-82. PMID 1459213 DOI: 10.1016/0531-5565(92)90068-B  1
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