Year |
Citation |
Score |
2023 |
Lin J, Ehinger E, Hanna DB, Qi Q, Wang T, Ghosheh Y, Mueller K, Anastos K, Lazar JM, Mack WJ, Tien PC, Berman JW, Cohen MH, Ofotokun I, Gange S, ... ... Ley K, et al. HIV infection and cardiovascular disease have both shared and distinct monocyte gene expression features: Women's Interagency HIV study. Plos One. 18: e0285926. PMID 37205656 DOI: 10.1371/journal.pone.0285926 |
0.699 |
|
2022 |
Vallejo J, Saigusa R, Gulati R, Suthahar SSA, Suryawanshi V, Alimadadi A, Durant CP, Ghosheh Y, Roy P, Ehinger E, Pattarabanjird T, Hanna DB, Landay AL, Tracy RP, Lazar JM, ... ... Ley K, et al. Author Correction: Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells. Bmc Biology. 20: 237. PMID 36266696 DOI: 10.1186/s12915-022-01440-x |
0.709 |
|
2022 |
Vallejo J, Saigusa R, Gulati R, Armstrong Suthahar SS, Suryawanshi V, Alimadadi A, Durant CP, Ghosheh Y, Roy P, Ehinger E, Pattarabanjird T, Hanna DB, Landay AL, Tracy RP, Lazar JM, ... ... Ley K, et al. Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells. Bmc Biology. 20: 193. PMID 36045343 DOI: 10.1186/s12915-022-01382-4 |
0.714 |
|
2022 |
Fan Z, Pitmon E, Wen L, Miller J, Ehinger E, Herro R, Liu W, Chen J, Mikulski Z, Conrad DJ, Marki A, Orecchioni M, Kumari P, Zhu YP, Marcovecchio PM, ... ... Ley K, et al. Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice. Journal of Immunology (Baltimore, Md. : 1950). 208: 745-752. PMID 35031577 DOI: 10.4049/jimmunol.1901171 |
0.72 |
|
2021 |
Winkels H, Ghosheh Y, Kobiyama K, Kiosses WB, Orecchioni M, Ehinger E, Suryawanshi V, Herrera-De La Mata S, Marchovecchio P, Riffelmacher T, Thiault N, Kronenberg M, Wolf D, Seumois G, Vijayanand P, ... Ley K, et al. Thymus-Derived CD4CD8 Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch. Journal of Immunology (Baltimore, Md. : 1950). PMID 34740961 DOI: 10.4049/jimmunol.2100208 |
0.735 |
|
2021 |
Buscher K, Heitplatz B, Van Marck V, Song J, Loismann S, Rixen R, Hüchtmann B, Kurian S, Ehinger E, Wolf D, Ley K, Pavenstaedt H, Reuter S. Data Driven Kidney Transplant Phenotyping as a Histology-independent Framework for Biomarker Discovery. Journal of the American Society of Nephrology : Jasn. PMID 34078665 DOI: 10.1681/ASN.2020121685 |
0.687 |
|
2020 |
Dong Y, Lee Y, Cui K, He M, Wang B, Bhattacharjee S, Zhu B, Yago T, Zhang K, Deng L, Ouyang K, Wen A, Cowan DB, Song K, Yu L, ... ... Ley K, et al. Epsin-mediated degradation of IP3R1 fuels atherosclerosis. Nature Communications. 11: 3984. PMID 32770009 DOI: 10.1038/S41467-020-17848-4 |
0.36 |
|
2020 |
Wolf D, Gerhardt T, Winkels H, Anto Michel N, Pramod AB, Ghosheh Y, Brunel S, Buscher K, Miller J, McArdle S, Baas L, Kobiyama K, Vassallo M, Ehinger E, Dileepan T, ... ... Ley K, et al. Pathogenic Autoimmunity in Atherosclerosis Evolves from Initially Protective ApoB-Reactive CD4 T-Regulatory Cells. Circulation. PMID 32703007 DOI: 10.1161/Circulationaha.119.042863 |
0.733 |
|
2020 |
Ehinger E, Ghosheh Y, Pramod AB, Lin J, Hanna DB, Mueller K, Durant CP, Baas L, Qi Q, Wang T, Buscher K, Anastos K, Lazar JM, Mack WJ, Tien PC, ... ... Ley K, et al. Classical Monocyte Transcriptomes Reveal Significant Anti-Inflammatory Statin Effect in Women with Chronic HIV. Cardiovascular Research. PMID 32658258 DOI: 10.1093/Cvr/Cvaa188 |
0.714 |
|
2020 |
Marcovecchio PM, Zhu YP, Hanna RN, Dinh HQ, Tacke R, Wu R, McArdle S, Reynolds S, Araujo DJ, Ley K, Hedrick CC. Kindlin-3 is essential for patrolling and phagocytosis functions of nonclassical monocytes during metastatic cancer surveillance. Journal of Leukocyte Biology. PMID 32386455 DOI: 10.1002/Jlb.4Hi0420-098R |
0.363 |
|
2020 |
Marki A, Ley K. Leaking chemokines confuse neutrophils. The Journal of Clinical Investigation. PMID 32202515 DOI: 10.1172/Jci136259 |
0.356 |
|
2019 |
Ramadass M, Johnson JL, Marki A, Zhang J, Wolf D, Kiosses WB, Pestonjamasp K, Ley K, Catz SD. The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration. Journal of Leukocyte Biology. PMID 30748033 DOI: 10.1002/Jlb.1Vma0818-320R |
0.358 |
|
2018 |
Brophy ML, Dong Y, Tao H, Yancey PG, Song K, Zhang K, Wen A, Wu H, Lee Y, Malovichko MV, Sithu SD, Wong S, Yu L, Kocher O, Bischoff J, ... ... Ley K, et al. Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation. Circulation Research. PMID 30595089 DOI: 10.1161/Circresaha.118.313028 |
0.363 |
|
2018 |
Riopel M, Vassallo M, Ehinger E, Pattison J, Bowden K, Winkels H, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, Larson CJ, Ley K, et al. CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice. Molecular Metabolism. PMID 30553772 DOI: 10.1016/J.Molmet.2018.11.011 |
0.761 |
|
2018 |
Mueller KAL, Hanna DB, Ehinger E, Xue X, Baas L, Gawaz MP, Geisler T, Anastos K, Cohen MH, Gange SJ, Heath SL, Lazar JM, Liu C, Mack WJ, Ofotokun I, ... ... Ley K, et al. Loss of CXCR4 on non-classical monocytes in participants of the Women's Interagency HIV Study (WIHS) with subclinical atherosclerosis. Cardiovascular Research. PMID 30520941 DOI: 10.1093/Cvr/Cvy292 |
0.717 |
|
2018 |
Winkels H, Ehinger E, Goshesh Y, Wolf D, Ley K. Atherosclerosis in the single-cell era. Current Opinion in Lipidology. PMID 30020199 DOI: 10.1097/Mol.0000000000000537 |
0.726 |
|
2018 |
Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, ... Ley K, et al. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. PMID 29875409 DOI: 10.1038/S41586-018-0198-8 |
0.352 |
|
2018 |
Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh H, Kobiyama K, Hamers A, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Pramod A, Ghosh A, Anto Michel N, Hoppe N, ... ... Ley K, et al. Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry. Circulation Research. PMID 29545366 DOI: 10.1161/Circresaha.117.312513 |
0.743 |
|
2018 |
Cochain C, Vafadarnejad E, Arampatzi P, Jaroslav P, Winkels H, Ley K, Wolf D, Saliba AE, Zernecke A. Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis. Circulation Research. PMID 29545365 DOI: 10.1161/Circresaha.117.312509 |
0.355 |
|
2018 |
Wolf D, Anto-Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann JD, Lim B, Bäuml M, Marki A, Mauler M, Duerschmied D, Fan Z, Winkels H, Sidler D, Diehl P, ... ... Ley K, et al. A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense. Nature Communications. 9: 525. PMID 29410422 DOI: 10.1038/S41467-018-02896-8 |
0.323 |
|
2018 |
Anto Michel N, Colberg C, Buscher K, Sommer B, Pramod AB, Ehinger E, Dufner B, Hoppe N, Pfeiffer K, Marchini T, Willecke F, Stachon P, Hilgendorf I, Heidt T, von Zur Mühlen C, ... ... Ley K, et al. Inflammatory Pathways Regulated By Tumor-Necrosis Receptor Associated Factor 1 Protect From Metabolic Consequences In Diet-Induced Obesity. Circulation Research. PMID 29358227 DOI: 10.1161/Circresaha.117.312055 |
0.742 |
|
2018 |
Winkels H, Ley K. Natural Killer Cells at Ease: Atherosclerosis Is Not Affected by Genetic Depletion or Hyperactivation of Natural Killer Cells. Circulation Research. 122: 6-7. PMID 29301835 DOI: 10.1161/Circresaha.117.312289 |
0.351 |
|
2018 |
Ehinger E, Akula Bala P, Lin J, Hanna DB, Mueller K, Baas L, Qi Q, Wang T, Buscher K, Liu Y, Anastos K, Lazar JM, Mack WJ, Tien PC, Cohen MH, ... ... Ley K, et al. Abstract 410: Statin Use May Alleviate Coagulation- and Inflammation-associated Gene Expression in Circulating Classical Monocytes in Women With Chronic HIV-1 Infection Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.410 |
0.722 |
|
2018 |
Wolf D, Michel NA, Buscher K, Ley K, Libby P, Bode C, Peter K, Zirlik A. Abstract 031: A Ligand-specific Blockade of the Integrin Mac-1 Selectively Targets Pathologic Vascular Inflammation While Maintaining Protective Host-defense Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.031 |
0.36 |
|
2018 |
Winkels H, Ehinger E, Vassalo M, Buscher K, Dinh H, Kobiyama K, Hamers A, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Bala PA, Ghosh AK, Michel NA, Hoppe N, ... ... Ley K, et al. Abstract 004: Comprehensive Assessment of Immune Cells in Mouse and Human Atherosclerosis by Single-cell RNA-sequencing and Mass Cytometry Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.004 |
0.734 |
|
2017 |
Buscher K, Marcovecchio P, Hedrick CC, Ley K. Patrolling Mechanics of Non-Classical Monocytes in Vascular Inflammation. Frontiers in Cardiovascular Medicine. 4: 80. PMID 29312957 DOI: 10.3389/Fcvm.2017.00080 |
0.324 |
|
2017 |
Marcovecchio PM, Thomas GD, Mikulski Z, Ehinger E, Mueller KAL, Blatchley A, Wu R, Miller YI, Nguyen AT, Taylor AM, McNamara CA, Ley K, Hedrick CC. Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28935758 DOI: 10.1161/Atvbaha.117.309123 |
0.729 |
|
2017 |
Marki A, Buscher K, Mikulski Z, Pries A, Ley K. Rolling neutrophils form tethers and slings under physiologic conditions in vivo. Journal of Leukocyte Biology. PMID 28821572 DOI: 10.1189/Jlb.1Ab0617-230R |
0.351 |
|
2017 |
Buscher K, Ehinger E, Gupta P, Pramod AB, Wolf D, Tweet G, Pan C, Mills CD, Lusis AJ, Ley K. Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival. Nature Communications. 8: 16041. PMID 28737175 DOI: 10.1038/Ncomms16041 |
0.738 |
|
2017 |
Peshkova IO, Fatkhullina AR, Mikulski Z, Ley K, Koltsova EK. IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis. Scientific Reports. 7: 2255. PMID 28536468 DOI: 10.1038/S41598-017-01828-8 |
0.366 |
|
2017 |
Thiriot A, Perdomo C, Cheng G, Novitzky-Basso I, McArdle S, Kishimoto JK, Barreiro O, Mazo I, Triboulet R, Ley K, Rot A, von Andrian UH. Differential DARC/ACKR1 expression distinguishes venular from non-venular endothelial cells in murine tissues. Bmc Biology. 15: 45. PMID 28526034 DOI: 10.1186/S12915-017-0381-7 |
0.35 |
|
2017 |
Ley K, Gerdes N, Winkels H. ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28360089 DOI: 10.1161/Atvbaha.117.308611 |
0.324 |
|
2017 |
Quintar A, McArdle S, Wolf D, Marki A, Ehinger E, Vassallo M, Miller JF, Mikulski Z, Ley K, Buscher K. Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis. Circulation Research. PMID 28302649 DOI: 10.1161/Circresaha.117.310739 |
0.794 |
|
2017 |
Abadier M, Ley K. P-selectin glycoprotein ligand-1 in T cells. Current Opinion in Hematology. PMID 28178038 DOI: 10.1097/Moh.0000000000000331 |
0.328 |
|
2017 |
Kimura T, Tse K, McArdle S, Gerhardt T, Miller J, Mikulski Z, Sidney J, Sette A, Wolf D, Ley K. Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00798.2016. PMID 28087520 DOI: 10.1152/Ajpheart.00798.2016 |
0.304 |
|
2016 |
McArdle S, Mikulski Z, Ley K. Live cell imaging to understand monocyte, macrophage, and dendritic cell function in atherosclerosis. The Journal of Experimental Medicine. PMID 27270892 DOI: 10.1084/Jem.20151885 |
0.305 |
|
2016 |
Fan Z, Ley K. Leukocyte Adhesion Deficiency IV. Monocyte Integrin Activation Deficiency in Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine. 193: 1075-7. PMID 27174474 DOI: 10.1164/Rccm.201512-2454Ed |
0.322 |
|
2016 |
Buscher K, Wang H, Zhang X, Striewski P, Wirth B, Saggu G, Lütke-Enking S, Mayadas TN, Ley K, Sorokin L, Song J. Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules. Nature Communications. 7: 10828. PMID 26940548 DOI: 10.1038/Ncomms10828 |
0.35 |
|
2016 |
Ley K, Rivera-Nieves J, Sandborn WJ, Shattil S. Integrin-based therapeutics: biological basis, clinical use and new drugs. Nature Reviews. Drug Discovery. 15: 173-83. PMID 26822833 DOI: 10.1038/Nrd.2015.10 |
0.315 |
|
2016 |
Ley K. 2015 Russell Ross Memorial Lecture in Vascular Biology: Protective Autoimmunity in Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 429-38. PMID 26821946 DOI: 10.1161/Atvbaha.115.306009 |
0.308 |
|
2016 |
Mikulski Z, Ley K. P-150 CCL21 Defect in Ileitis-Prone SAMP1/YitFc Mice Inflammatory Bowel Diseases. 22: S56. DOI: 10.1097/01.Mib.0000480246.10020.6D |
0.305 |
|
2015 |
Côte M, Fos C, Canonigo-Balancio AJ, Ley K, Bécart S, Altman A. SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1. Journal of Cell Science. 128: 4341-52. PMID 26483383 DOI: 10.1242/Jcs.172742 |
0.317 |
|
2015 |
Block H, Stadtmann A, Riad D, Rossaint J, Sohlbach C, Germena G, Wu D, Simon SI, Ley K, Zarbock A. Gnb isoforms orchestrate a signaling pathway comprising Rac1 and Plcβ2/3 leading to LFA-1 activation and neutrophil arrest in vivo. Blood. PMID 26468229 DOI: 10.1182/Blood-2015-06-651034 |
0.353 |
|
2015 |
Wolf D, Zirlik A, Ley K. Beyond vascular inflammation--recent advances in understanding atherosclerosis. Cellular and Molecular Life Sciences : Cmls. 72: 3853-69. PMID 26100516 DOI: 10.1007/S00018-015-1971-6 |
0.363 |
|
2015 |
Gerhardt T, Ley K. Monocyte trafficking across the vessel wall. Cardiovascular Research. 107: 321-30. PMID 25990461 DOI: 10.1093/Cvr/Cvv147 |
0.367 |
|
2015 |
Marki A, Esko JD, Pries AR, Ley K. Role of the endothelial surface layer in neutrophil recruitment. Journal of Leukocyte Biology. 98: 503-15. PMID 25979432 DOI: 10.1189/Jlb.3Mr0115-011R |
0.346 |
|
2015 |
Quintar AA, Hedrick CC, Ley K. Monocyte phenotypes: when local education counts. The Journal of Experimental Medicine. 212: 432. PMID 25847970 DOI: 10.1084/Jem.2124Insight1 |
0.706 |
|
2015 |
Mills CD, Lenz LL, Ley K. Macrophages at the fork in the road to health or disease. Frontiers in Immunology. 6: 59. PMID 25762997 DOI: 10.3389/Fimmu.2015.00059 |
0.309 |
|
2015 |
McArdle S, Chodaczek G, Ray N, Ley K. Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries. Journal of Biomedical Optics. 20: 26005. PMID 25710308 DOI: 10.1117/1.Jbo.20.2.026005 |
0.332 |
|
2015 |
Wolf D, Ley K. Waking up the stem cell niche: how hematopoietic stem cells generate inflammatory monocytes after stroke. Circulation Research. 116: 389-92. PMID 25634966 DOI: 10.1161/Circresaha.114.305678 |
0.306 |
|
2015 |
Mikulski Z, Johnson R, Shaked I, Kim G, Nowyhed H, Goodman W, Chodaczek G, Pizarro TT, Cominelli F, Ley K. SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration. Gastroenterology. 148: 783-793.e5. PMID 25620669 DOI: 10.1053/J.Gastro.2015.01.027 |
0.334 |
|
2015 |
Li J, Ley K. Lymphocyte migration into atherosclerotic plaque. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 40-9. PMID 25301842 DOI: 10.1161/Atvbaha.114.303227 |
0.341 |
|
2014 |
Mills CD, Ley K. M1 and M2 macrophages: the chicken and the egg of immunity. Journal of Innate Immunity. 6: 716-26. PMID 25138714 DOI: 10.1159/000364945 |
0.303 |
|
2014 |
Koltsova EK, Sundd P, Zarpellon A, Ouyang H, Mikulski Z, Zampolli A, Ruggeri ZM, Ley K. Genetic deletion of platelet glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis. Thrombosis and Haemostasis. 112: 1252-63. PMID 25104056 DOI: 10.1160/Th14-02-0130 |
0.371 |
|
2014 |
Gjurich BN, Taghavie-Moghadam PL, Ley K, Galkina EV. L-selectin deficiency decreases aortic B1a and Breg subsets and promotes atherosclerosis. Thrombosis and Haemostasis. 112: 803-11. PMID 24989887 DOI: 10.1160/Th13-10-0865 |
0.359 |
|
2013 |
Tse K, Tse H, Sidney J, Sette A, Ley K. T cells in atherosclerosis. International Immunology. 25: 615-22. PMID 24154816 DOI: 10.1093/Intimm/Dxt043 |
0.329 |
|
2013 |
Stadtmann A, Germena G, Block H, Boras M, Rossaint J, Sundd P, Lefort C, Fisher CI, Buscher K, Gelschefarth B, Urzainqui A, Gerke V, Ley K, Zarbock A. The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow. The Journal of Experimental Medicine. 210: 2171-80. PMID 24127491 DOI: 10.1084/Jem.20130664 |
0.309 |
|
2013 |
Ley K. Leukocytes talking to VE-cadherin. Blood. 122: 2300-1. PMID 24092927 DOI: 10.1182/Blood-2013-08-519918 |
0.304 |
|
2013 |
Koltsova EK, Hedrick CC, Ley K. Myeloid cells in atherosclerosis: a delicate balance of anti-inflammatory and proinflammatory mechanisms. Current Opinion in Lipidology. 24: 371-80. PMID 24005215 DOI: 10.1097/Mol.0B013E328363D298 |
0.373 |
|
2013 |
Sundd P, Pospieszalska MK, Ley K. Neutrophil rolling at high shear: flattening, catch bond behavior, tethers and slings. Molecular Immunology. 55: 59-69. PMID 23141302 DOI: 10.1016/J.Molimm.2012.10.025 |
0.324 |
|
2013 |
Tse K, Ley K. Transforming growth factor-β: transforming plaque to stability. European Heart Journal. 34: 3684-6. PMID 22843445 DOI: 10.1093/Eurheartj/Ehs228 |
0.341 |
|
2012 |
Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, ... ... Ley K, et al. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 151: 138-52. PMID 23021221 DOI: 10.1016/J.Cell.2012.06.054 |
0.367 |
|
2012 |
Koltsova EK, Garcia Z, Chodaczek G, Landau M, McArdle S, Scott SR, von Vietinghoff S, Galkina E, Miller YI, Acton ST, Ley K. Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis. The Journal of Clinical Investigation. 122: 3114-26. PMID 22886300 DOI: 10.1172/Jci61758 |
0.388 |
|
2012 |
Axelsson J, Xu D, Kang BN, Nussbacher JK, Handel TM, Ley K, Sriramarao P, Esko JD. Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice. Blood. 120: 1742-51. PMID 22791291 DOI: 10.1182/Blood-2012-03-417139 |
0.377 |
|
2012 |
Sundd P, Gutierrez E, Koltsova EK, Kuwano Y, Fukuda S, Pospieszalska MK, Groisman A, Ley K. 'Slings' enable neutrophil rolling at high shear. Nature. 488: 399-403. PMID 22763437 DOI: 10.1038/Nature11248 |
0.335 |
|
2012 |
Lefort CT, Ley K. Neutrophil arrest by LFA-1 activation. Frontiers in Immunology. 3: 157. PMID 22701459 DOI: 10.3389/Fimmu.2012.00157 |
0.337 |
|
2012 |
Shaked I, Ley K. Protective role for myeloid specific KLF2 in atherosclerosis. Circulation Research. 110: 1266. PMID 22581916 DOI: 10.1161/Circresaha.112.270991 |
0.392 |
|
2012 |
Block H, Ley K, Zarbock A. Severe impairment of leukocyte recruitment in ppGalNAcT-1-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 5674-81. PMID 22544932 DOI: 10.4049/Jimmunol.1200392 |
0.363 |
|
2012 |
Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K. Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood. 119: 4275-82. PMID 22431571 DOI: 10.1182/Blood-2011-08-373118 |
0.358 |
|
2012 |
Bertram A, Zhang H, von Vietinghoff S, de Pablo C, Haller H, Shushakova N, Ley K. Protein kinase C-θ is required for murine neutrophil recruitment and adhesion strengthening under flow. Journal of Immunology (Baltimore, Md. : 1950). 188: 4043-51. PMID 22403440 DOI: 10.4049/Jimmunol.1101651 |
0.383 |
|
2012 |
Wingender G, Hiss M, Engel I, Peukert K, Ley K, Haller H, Kronenberg M, von Vietinghoff S. Neutrophilic granulocytes modulate invariant NKT cell function in mice and humans. Journal of Immunology (Baltimore, Md. : 1950). 188: 3000-8. PMID 22387552 DOI: 10.4049/Jimmunol.1101273 |
0.389 |
|
2012 |
Hanna RN, Shaked I, Hubbeling HG, Punt JA, Wu R, Herrley E, Zaugg C, Pei H, Geissmann F, Ley K, Hedrick CC. NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis. Circulation Research. 110: 416-27. PMID 22194622 DOI: 10.1161/Circresaha.111.253377 |
0.31 |
|
2012 |
Doran AC, Lipinski MJ, Oldham SN, Garmey JC, Campbell KA, Skaflen MD, Cutchins A, Lee DJ, Glover DK, Kelly KA, Galkina EV, Ley K, Witztum JL, Tsimikas S, Bender TP, et al. B-cell aortic homing and atheroprotection depend on Id3. Circulation Research. 110: e1-12. PMID 22034493 DOI: 10.1161/Circresaha.111.256438 |
0.319 |
|
2012 |
Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K. Distinct Roles for Talin-1 and Kindlin-3 in Regulating LFA-1 Conformation during Neutrophil Rolling and Arrest Biophysical Journal. 102: 347a. DOI: 10.1016/J.Bpj.2011.11.1900 |
0.321 |
|
2012 |
Sundd P, Gutierrez E, Pospieszalska MK, Koltsova E, Kuwano Y, Fukuda S, Groisman A, Ley K. Neutrophil Sling: a New Cell-Autonomous Adhesive Structure Enabling Rolling at High Shear Stress Biophysical Journal. 102: 194a-195a. DOI: 10.1016/J.Bpj.2011.11.1061 |
0.327 |
|
2011 |
Zarbock A, Ley K, McEver RP, Hidalgo A. Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow. Blood. 118: 6743-51. PMID 22021370 DOI: 10.1182/Blood-2011-07-343566 |
0.34 |
|
2011 |
Ley K. CD63 positions CD62P for rolling. Blood. 118: 4012-3. PMID 21998333 DOI: 10.1182/Blood-2011-08-372318 |
0.309 |
|
2011 |
Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, ... Ley K, et al. Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease. Science Signaling. 4: ra57. PMID 21900205 DOI: 10.1126/Scisignal.2001811 |
0.347 |
|
2011 |
Koltsova EK, Ley K. How dendritic cells shape atherosclerosis. Trends in Immunology. 32: 540-7. PMID 21835696 DOI: 10.1016/J.It.2011.07.001 |
0.309 |
|
2011 |
Butcher MJ, Herre M, Ley K, Galkina E. Flow cytometry analysis of immune cells within murine aortas. Journal of Visualized Experiments : Jove. PMID 21750492 DOI: 10.3791/2848 |
0.362 |
|
2011 |
Ley K, Miller YI, Hedrick CC. Monocyte and macrophage dynamics during atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1506-16. PMID 21677293 DOI: 10.1161/Atvbaha.110.221127 |
0.391 |
|
2011 |
Tang J, Zarbock A, Gomez I, Wilson CL, Lefort CT, Stadtmann A, Bell B, Huang LC, Ley K, Raines EW. Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites. Blood. 118: 786-94. PMID 21628404 DOI: 10.1182/Blood-2010-11-321406 |
0.352 |
|
2011 |
von Vietinghoff S, Koltsova EK, Mestas J, Diehl CJ, Witztum JL, Ley K. Mycophenolate mofetil decreases atherosclerotic lesion size by depression of aortic T-lymphocyte and interleukin-17-mediated macrophage accumulation. Journal of the American College of Cardiology. 57: 2194-204. PMID 21596236 DOI: 10.1016/J.Jacc.2010.12.030 |
0.326 |
|
2011 |
Stadtmann A, Brinkhaus L, Mueller H, Rossaint J, Bolomini-Vittori M, Bergmeier W, Van Aken H, Wagner DD, Laudanna C, Ley K, Zarbock A. Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling. European Journal of Immunology. 41: 2074-85. PMID 21480213 DOI: 10.1002/Eji.201041196 |
0.354 |
|
2011 |
Sundd P, Gutierrez E, Petrich BG, Ginsberg MH, Groisman A, Ley K. Live cell imaging of paxillin in rolling neutrophils by dual-color quantitative dynamic footprinting. Microcirculation (New York, N.Y. : 1994). 18: 361-72. PMID 21418380 DOI: 10.1111/J.1549-8719.2011.00090.X |
0.308 |
|
2011 |
Zarbock A, Ley K. Protein tyrosine kinases in neutrophil activation and recruitment. Archives of Biochemistry and Biophysics. 510: 112-9. PMID 21338576 DOI: 10.1016/J.Abb.2011.02.009 |
0.322 |
|
2011 |
Morris MA, McDuffie M, Nadler JL, Ley K. Prevention, but not cure, of autoimmune diabetes in a NOD.scid transfer model by FTY720 despite effective modulation of blood T cells. Autoimmunity. 44: 115-28. PMID 20695767 DOI: 10.3109/08916934.2010.499885 |
0.336 |
|
2011 |
Ley K. The Microcirculation in Inflammation Comprehensive Physiology. 387-448. DOI: 10.1002/Cphy.Cp020409 |
0.366 |
|
2010 |
von Vietinghoff S, Ley K. Interleukin 17 in vascular inflammation. Cytokine & Growth Factor Reviews. 21: 463-9. PMID 21075042 DOI: 10.1016/J.Cytogfr.2010.10.003 |
0.32 |
|
2010 |
Little KM, Smalley DM, Harthun NL, Ley K. The plasma microparticle proteome. Seminars in Thrombosis and Hemostasis. 36: 845-56. PMID 21049385 DOI: 10.1055/S-0030-1267038 |
0.759 |
|
2010 |
Gorfu G, Rivera-Nieves J, Hoang S, Abbott DW, Arbenz-Smith K, Azar DW, Pizarro TT, Cominelli F, McDuffie M, Ley K. Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 5561-8. PMID 20926792 DOI: 10.4049/Jimmunol.0903938 |
0.352 |
|
2010 |
Sundd P, Gutierrez E, Pospieszalska MK, Zhang H, Groisman A, Ley K. Quantitative dynamic footprinting microscopy reveals mechanisms of neutrophil rolling. Nature Methods. 7: 821-4. PMID 20871617 DOI: 10.1038/Nmeth.1508 |
0.321 |
|
2010 |
Anderson CR, Rychak JJ, Backer M, Backer J, Ley K, Klibanov AL. scVEGF microbubble ultrasound contrast agents: a novel probe for ultrasound molecular imaging of tumor angiogenesis. Investigative Radiology. 45: 579-85. PMID 20733505 DOI: 10.1097/Rli.0B013E3181Efd581 |
0.667 |
|
2010 |
Koltsova EK, Ley K. The mysterious ways of the chemokine CXCL5. Immunity. 33: 7-9. PMID 20643334 DOI: 10.1016/J.Immuni.2010.07.012 |
0.321 |
|
2010 |
von Vietinghoff S, Asagiri M, Azar D, Hoffmann A, Ley K. Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 670-8. PMID 20519647 DOI: 10.4049/Jimmunol.1000339 |
0.35 |
|
2010 |
Kuwano Y, Spelten O, Zhang H, Ley K, Zarbock A. Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils. Blood. 116: 617-24. PMID 20445017 DOI: 10.1182/Blood-2010-01-266122 |
0.311 |
|
2010 |
von Vietinghoff S, Ouyang H, Ley K. Mycophenolic acid suppresses granulopoiesis by inhibition of interleukin-17 production. Kidney International. 78: 79-88. PMID 20375992 DOI: 10.1038/Ki.2010.84 |
0.309 |
|
2010 |
Smith E, Prasad KMR, Butcher M, Dobrian A, Kolls JK, Ley K, Galkina E. Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice Circulation. 121: 1746-1755. PMID 20368519 DOI: 10.1161/Circulationaha.109.924886 |
0.312 |
|
2010 |
Gleissner CA, Shaked I, Little KM, Ley K. CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages. Journal of Immunology (Baltimore, Md. : 1950). 184: 4810-8. PMID 20335529 DOI: 10.4049/Jimmunol.0901368 |
0.774 |
|
2010 |
Buscher K, Riese SB, Shakibaei M, Reich C, Dernedde J, Tauber R, Ley K. The transmembrane domains of L-selectin and CD44 regulate receptor cell surface positioning and leukocyte adhesion under flow. The Journal of Biological Chemistry. 285: 13490-7. PMID 20212041 DOI: 10.1074/Jbc.M110.102640 |
0.308 |
|
2010 |
Mueller H, Stadtmann A, Van Aken H, Hirsch E, Wang D, Ley K, Zarbock A. Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways. Blood. 115: 3118-27. PMID 20167705 DOI: 10.1182/Blood-2009-11-254185 |
0.304 |
|
2010 |
Little KM, Lee JK, Ley K. ReSASC: a resampling-based algorithm to determine differential protein expression from spectral count data. Proteomics. 10: 1212-22. PMID 20058246 DOI: 10.1002/Pmic.200900328 |
0.758 |
|
2010 |
Gleissner CA, Shaked I, Erbel C, Böckler D, Katus HA, Ley K. CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages. Circulation Research. 106: 203-11. PMID 19910578 DOI: 10.1161/Circresaha.109.199505 |
0.345 |
|
2010 |
Harthun NL, Smalley DM, Little KM, Ley K. Proteomic Analysis of Microparticles from Patients with Abdominal Aortic Aneurysms Journal of Vascular Surgery. 52: 1743. DOI: 10.1016/J.Jvs.2010.10.027 |
0.743 |
|
2010 |
Sundd P, Gutierrez E, Pospieszalska M, Groisman A, Ley K. Stressed and Compressed Molecular Bonds Revealed in Footprints of Rolling Neutrophils using Total Internal Reflection Fluorescence Microscopy Biophysical Journal. 98: 595a. DOI: 10.1016/J.Bpj.2009.12.3236 |
0.338 |
|
2009 |
Pospieszalska MK, Ley K. Dynamics of Microvillus Extension and Tether Formation in Rolling Leukocytes. Cellular and Molecular Bioengineering. 2: 207-217. PMID 20046963 DOI: 10.1007/S12195-009-0063-9 |
0.308 |
|
2009 |
Gorfu G, Rivera-Nieves J, Ley K. Role of β7 integrins in intestinal lymphocyte homing and retention Current Molecular Medicine. 9: 836-850. PMID 19860663 DOI: 10.2174/156652409789105525 |
0.334 |
|
2009 |
Koltsova E, Ley K. Tyrosine sulfation of leukocyte adhesion molecules and chemokine receptors promotes atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1709-11. PMID 19846834 DOI: 10.1161/Atvbaha.109.195552 |
0.383 |
|
2009 |
Smith E, von Vietinghoff S, Stark MA, Zarbock A, Sanders JM, Duley A, Rivera-Nieves J, Bender TP, Ley K. T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo. Journal of Immunology (Baltimore, Md. : 1950). 183: 5685-93. PMID 19843951 DOI: 10.4049/Jimmunol.0900887 |
0.726 |
|
2009 |
Reutershan J, Saprito MS, Wu D, Rückle T, Ley K. Phosphoinositide 3-kinase gamma required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung. The European Respiratory Journal. 35: 1137-47. PMID 19797129 DOI: 10.1183/09031936.00085509 |
0.342 |
|
2009 |
DiStasi MR, Ley K. Opening the flood-gates: how neutrophil-endothelial interactions regulate permeability. Trends in Immunology. 30: 547-56. PMID 19783480 DOI: 10.1016/J.It.2009.07.012 |
0.332 |
|
2009 |
Zarbock A, Distasi MR, Smith E, Sanders JM, Kronke G, Harry BL, von Vietinghoff S, Buscher K, Nadler JL, Ley K. Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI). Journal of Immunology (Baltimore, Md. : 1950). 183: 4715-22. PMID 19752233 DOI: 10.4049/Jimmunol.0802592 |
0.323 |
|
2009 |
Zarbock A, Müller H, Kuwano Y, Ley K. PSGL-1-dependent myeloid leukocyte activation. Journal of Leukocyte Biology. 86: 1119-24. PMID 19703898 DOI: 10.1189/Jlb.0209117 |
0.354 |
|
2009 |
Ferrante EA, Pickard JE, Rychak J, Klibanov A, Ley K. Dual targeting improves microbubble contrast agent adhesion to VCAM-1 and P-selectin under flow. Journal of Controlled Release : Official Journal of the Controlled Release Society. 140: 100-7. PMID 19666063 DOI: 10.1016/J.Jconrel.2009.08.001 |
0.691 |
|
2009 |
Sperandio M, Gleissner CA, Ley K. Glycosylation in immune cell trafficking. Immunological Reviews. 230: 97-113. PMID 19594631 DOI: 10.1111/J.1600-065X.2009.00795.X |
0.352 |
|
2009 |
Zarbock A, Ley K. New insights into leukocyte recruitment by intravital microscopy. Current Topics in Microbiology and Immunology. 334: 129-52. PMID 19521684 DOI: 10.1007/978-3-540-93864-4_6 |
0.331 |
|
2009 |
Reutershan J, Harry B, Chang D, Bagby GJ, Ley K. DARC on RBC limits lung injury by balancing compartmental distribution of CXC chemokines. European Journal of Immunology. 39: 1597-607. PMID 19499525 DOI: 10.1002/Eji.200839089 |
0.382 |
|
2009 |
Ley K. Cell adhesion under flow. Microcirculation (New York, N.Y. : 1994). 16: 1-2. PMID 19191171 DOI: 10.1080/10739680802644415 |
0.348 |
|
2009 |
Zarbock A, Ley K. Neutrophil adhesion and activation under flow. Microcirculation (New York, N.Y. : 1994). 16: 31-42. PMID 19037827 DOI: 10.1080/10739680802350104 |
0.354 |
|
2009 |
Rivera-Nieves J, Gorfu G, Ley K. Leukocyte adhesion molecules in animal models of inflammatory bowel disease. Inflammatory Bowel Diseases. 14: 1715-35. PMID 18523998 DOI: 10.1002/Ibd.20501 |
0.337 |
|
2008 |
Mestas J, Ley K. Monocyte-endothelial cell interactions in the development of atherosclerosis. Trends in Cardiovascular Medicine. 18: 228-32. PMID 19185814 DOI: 10.1016/J.Tcm.2008.11.004 |
0.369 |
|
2008 |
Ley K, Zhang H. Dances with leukocytes: how tetraspanin-enriched microdomains assemble to form endothelial adhesive platforms. The Journal of Cell Biology. 183: 375-6. PMID 18981226 DOI: 10.1083/Jcb.200809173 |
0.334 |
|
2008 |
von Vietinghoff S, Ley K. Homeostatic regulation of blood neutrophil counts. Journal of Immunology (Baltimore, Md. : 1950). 181: 5183-8. PMID 18832668 DOI: 10.4049/Jimmunol.181.8.5183 |
0.319 |
|
2008 |
Zarbock A, Abram CL, Hundt M, Altman A, Lowell CA, Ley K. PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling. The Journal of Experimental Medicine. 205: 2339-47. PMID 18794338 DOI: 10.1084/Jem.20072660 |
0.344 |
|
2008 |
Gleissner CA, von Hundelshausen P, Ley K. Platelet chemokines in vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1920-7. PMID 18723831 DOI: 10.1161/Atvbaha.108.169417 |
0.363 |
|
2008 |
Harry BL, Sanders JM, Feaver RE, Lansey M, Deem TL, Zarbock A, Bruce AC, Pryor AW, Gelfand BD, Blackman BR, Schwartz MA, Ley K. Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2003-8. PMID 18688018 DOI: 10.1161/Atvbaha.108.164707 |
0.389 |
|
2008 |
Smith E, Stark MA, Zarbock A, Burcin TL, Bruce AC, Vaswani D, Foley P, Ley K. IL-17A inhibits the expansion of IL-17A-producing T cells in mice through "short-loop" inhibition via IL-17 receptor. Journal of Immunology (Baltimore, Md. : 1950). 181: 1357-64. PMID 18606690 DOI: 10.4049/Jimmunol.181.2.1357 |
0.712 |
|
2008 |
Frommhold D, Ludwig A, Bixel MG, Zarbock A, Babushkina I, Weissinger M, Cauwenberghs S, Ellies LG, Marth JD, Beck-Sickinger AG, Sixt M, Lange-Sperandio B, Zernecke A, Brandt E, Weber C, ... ... Ley K, et al. Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. The Journal of Experimental Medicine. 205: 1435-46. PMID 18519646 DOI: 10.1084/Jem.20070846 |
0.365 |
|
2008 |
Alon R, Ley K. Cells on the run: shear-regulated integrin activation in leukocyte rolling and arrest on endothelial cells. Current Opinion in Cell Biology. 20: 525-32. PMID 18499427 DOI: 10.1016/J.Ceb.2008.04.003 |
0.347 |
|
2008 |
Galkina E, Ley K. Leukocyte influx in atherosclerosis. Current Drug Targets. 8: 1239-48. PMID 18220701 DOI: 10.2174/138945007783220650 |
0.396 |
|
2008 |
Gleissner CA, Ley K. CXCL4 in atherosclerosis: possible roles in monocyte arrest and macrophage foam cell formation. Thrombosis and Haemostasis. 98: 917-8. PMID 18000592 DOI: 10.1160/Th07-09-0567 |
0.353 |
|
2007 |
Zarbock A, Ley K. Mechanisms and consequences of neutrophil interaction with the endothelium. The American Journal of Pathology. 172: 1-7. PMID 18079440 DOI: 10.2353/Ajpath.2008.070502 |
0.35 |
|
2007 |
Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K. IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 8274-9. PMID 18056371 DOI: 10.4049/Jimmunol.179.12.8274 |
0.725 |
|
2007 |
Tenno M, Ohtsubo K, Hagen FK, Ditto D, Zarbock A, Schaerli P, von Andrian UH, Ley K, Le D, Tabak LA, Marth JD. Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity. Molecular and Cellular Biology. 27: 8783-96. PMID 17923703 DOI: 10.1128/Mcb.01204-07 |
0.339 |
|
2007 |
Galkina E, Harry BL, Ludwig A, Liehn EA, Sanders JM, Bruce A, Weber C, Ley K. CXCR6 promotes atherosclerosis by supporting T-cell homing, interferon-gamma production, and macrophage accumulation in the aortic wall. Circulation. 116: 1801-11. PMID 17909108 DOI: 10.1161/Circulationaha.106.678474 |
0.326 |
|
2007 |
Zarbock A, Deem TL, Burcin TL, Ley K. Galphai2 is required for chemokine-induced neutrophil arrest. Blood. 110: 3773-9. PMID 17699741 DOI: 10.1182/Blood-2007-06-094565 |
0.393 |
|
2007 |
Reutershan J, Cagnina RE, Chang D, Linden J, Ley K. Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury. Journal of Immunology (Baltimore, Md. : 1950). 179: 1254-63. PMID 17617618 DOI: 10.4049/Jimmunol.179.2.1254 |
0.361 |
|
2007 |
Gleissner CA, Leitinger N, Ley K. Effects of native and modified low-density lipoproteins on monocyte recruitment in atherosclerosis. Hypertension (Dallas, Tex. : 1979). 50: 276-83. PMID 17548720 DOI: 10.1161/Hypertensionaha.107.089854 |
0.372 |
|
2007 |
Zarbock A, Lowell CA, Ley K. Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1. Immunity. 26: 773-83. PMID 17543554 DOI: 10.1016/J.Immuni.2007.04.011 |
0.34 |
|
2007 |
Rychak JJ, Klibanov AL, Ley KF, Hossack JA. Enhanced targeting of ultrasound contrast agents using acoustic radiation force. Ultrasound in Medicine & Biology. 33: 1132-9. PMID 17445966 DOI: 10.1016/J.Ultrasmedbio.2007.01.005 |
0.672 |
|
2007 |
Stockton R, Reutershan J, Scott D, Sanders J, Ley K, Schwartz MA. Induction of vascular permeability: beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK. Molecular Biology of the Cell. 18: 2346-55. PMID 17429073 DOI: 10.1091/Mbc.E06-07-0584 |
0.312 |
|
2007 |
Reutershan J, Stockton R, Zarbock A, Sullivan GW, Chang D, Scott D, Schwartz MA, Ley K. Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration. American Journal of Respiratory and Critical Care Medicine. 175: 1027-35. PMID 17322107 DOI: 10.1164/Rccm.200612-1822Oc |
0.314 |
|
2007 |
Cho HJ, Shashkin P, Gleissner CA, Dunson D, Jain N, Lee JK, Miller Y, Ley K. Induction of dendritic cell-like phenotype in macrophages during foam cell formation. Physiological Genomics. 29: 149-60. PMID 17244792 DOI: 10.1152/Physiolgenomics.00051.2006 |
0.349 |
|
2007 |
Zarbock A, Singbartl K, Ley K. Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation. The Journal of Clinical Investigation. 116: 3211-9. PMID 17143330 DOI: 10.1172/Jci29499 |
0.308 |
|
2007 |
Ley K. To transmigrate or not to transmigrate Blood. 109: 5072-5073. DOI: 10.1182/Blood-2007-03-081851 |
0.311 |
|
2006 |
Klibanov AL, Rychak JJ, Yang WC, Alikhani S, Li B, Acton S, Lindner JR, Ley K, Kaul S. Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media & Molecular Imaging. 1: 259-66. PMID 17191766 DOI: 10.1002/Cmmi.113 |
0.689 |
|
2006 |
Sperandio M, Pickard J, Unnikrishnan S, Acton ST, Ley K. Analysis of leukocyte rolling in vivo and in vitro. Methods in Enzymology. 416: 346-71. PMID 17113878 DOI: 10.1016/S0076-6879(06)16023-1 |
0.353 |
|
2006 |
Sperandio M, Frommhold D, Babushkina I, Ellies LG, Olson TS, Smith ML, Fritzsching B, Pauly E, Smith DF, Nobiling R, Linderkamp O, Marth JD, Ley K. Alpha 2,3-sialyltransferase-IV is essential for L-selectin ligand function in inflammation. European Journal of Immunology. 36: 3207-15. PMID 17111351 DOI: 10.1002/Eji.200636157 |
0.31 |
|
2006 |
Rivera-Nieves J, Ho J, Bamias G, Ivashkina N, Ley K, Oppermann M, Cominelli F. Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitis. Gastroenterology. 131: 1518-29. PMID 17101325 DOI: 10.1053/J.Gastro.2006.08.031 |
0.324 |
|
2006 |
Rychak JJ, Li B, Acton ST, Leppänen A, Cummings RD, Ley K, Klibanov AL. Selectin ligands promote ultrasound contrast agent adhesion under shear flow. Molecular Pharmaceutics. 3: 516-24. PMID 17009850 DOI: 10.1021/mp0600541 |
0.677 |
|
2006 |
Smith DF, Deem TL, Bruce AC, Reutershan J, Wu D, Ley K. Leukocyte phosphoinositide-3 kinase {gamma} is required for chemokine-induced, sustained adhesion under flow in vivo. Journal of Leukocyte Biology. 80: 1491-9. PMID 16997858 DOI: 10.1189/Jlb.0306227 |
0.388 |
|
2006 |
Whetzel AM, Bolick DT, Srinivasan S, Macdonald TL, Morris MA, Ley K, Hedrick CC. Sphingosine-1 phosphate prevents monocyte/endothelial interactions in type 1 diabetic NOD mice through activation of the S1P1 receptor. Circulation Research. 99: 731-9. PMID 16960101 DOI: 10.1161/01.Res.0000244088.33375.52 |
0.301 |
|
2006 |
Ley K, Smith E, Stark MA. IL-17A-producing neutrophil-regulatory Tn lymphocytes. Immunologic Research. 34: 229-42. PMID 16891673 DOI: 10.1385/Ir:34:3:229 |
0.729 |
|
2006 |
Rychak JJ, Lindner JR, Ley K, Klibanov AL. Deformable gas-filled microbubbles targeted to P-selectin. Journal of Controlled Release : Official Journal of the Controlled Release Society. 114: 288-99. PMID 16887229 DOI: 10.1016/J.Jconrel.2006.06.008 |
0.691 |
|
2006 |
Galkina E, Kadl A, Sanders J, Varughese D, Sarembock IJ, Ley K. Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. The Journal of Experimental Medicine. 203: 1273-82. PMID 16682495 DOI: 10.1084/Jem.20052205 |
0.382 |
|
2006 |
Rivera-Nieves J, Burcin TL, Olson TS, Morris MA, McDuffie M, Cominelli F, Ley K. Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis. The Journal of Experimental Medicine. 203: 907-17. PMID 16567389 DOI: 10.1084/Jem.20052530 |
0.383 |
|
2006 |
Olson TS, Reuter BK, Scott KG, Morris MA, Wang XM, Hancock LN, Burcin TL, Cohn SM, Ernst PB, Cominelli F, Meddings JB, Ley K, Pizarro TT. The primary defect in experimental ileitis originates from a nonhematopoietic source. The Journal of Experimental Medicine. 203: 541-52. PMID 16505137 DOI: 10.1084/Jem.20050407 |
0.347 |
|
2006 |
Reutershan J, Morris MA, Burcin TL, Smith DF, Chang D, Saprito MS, Ley K. Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung. The Journal of Clinical Investigation. 116: 695-702. PMID 16485040 DOI: 10.1172/Jci27009 |
0.351 |
|
2006 |
Basit A, Reutershan J, Morris MA, Solga M, Rose CE, Ley K. ICAM-1 and LFA-1 play critical roles in LPS-induced neutrophil recruitment into the alveolar space. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L200-7. PMID 16461431 DOI: 10.1152/Ajplung.00346.2005 |
0.517 |
|
2006 |
Chesnutt BC, Smith DF, Raffler NA, Smith ML, White EJ, Ley K. Induction of LFA-1-dependent neutrophil rolling on ICAM-1 by engagement of E-selectin. Microcirculation (New York, N.Y. : 1994). 13: 99-109. PMID 16459323 DOI: 10.1080/10739680500466376 |
0.303 |
|
2006 |
Bachmann C, Klibanov AL, Olson TS, Sonnenschein JR, Rivera-Nieves J, Cominelli F, Ley KF, Lindner JR, Pizarro TT. Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease. Gastroenterology. 130: 8-16. PMID 16401463 DOI: 10.1053/J.Gastro.2005.11.009 |
0.777 |
|
2006 |
Galkina E, Ley K. Double jeopardy: how soluble P-selectin activates leukocytes in peripheral arterial occlusive disease. Circulation Research. 98: 12-4. PMID 16397153 DOI: 10.1161/01.Res.0000200409.65882.14 |
0.377 |
|
2006 |
Klibanov AL, Hossack J, Cho YK, Yang WC, Rychak JJ, Ley KF. Gas‐filled microbubbles—Contrast agents for targeted molecular imaging The Journal of the Acoustical Society of America. 119: 3438-3438. DOI: 10.1121/1.4786919 |
0.657 |
|
2006 |
Klibanov A, Rychak J, Yang W, Li B, Acton S, Lindner J, Ley K, Kaul S. CMR 2005: 8.03: Targeted ultrasound contrast agents for molecular imaging in high-shear flow Contrast Media & Molecular Imaging. 1: 74-74. DOI: 10.1002/Cmmi.48 |
0.642 |
|
2005 |
Shashkin P, Dragulev B, Ley K. Macrophage differentiation to foam cells. Current Pharmaceutical Design. 11: 3061-3072. PMID 16178764 DOI: 10.2174/1381612054865064 |
0.316 |
|
2005 |
Smalley DM, Ley K. L-selectin: mechanisms and physiological significance of ectodomain cleavage. Journal of Cellular and Molecular Medicine. 9: 255-66. PMID 15963248 DOI: 10.1111/J.1582-4934.2005.Tb00354.X |
0.305 |
|
2005 |
Reutershan J, Basit A, Galkina EV, Ley K. Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L807-15. PMID 15951336 DOI: 10.1152/Ajplung.00477.2004 |
0.437 |
|
2005 |
Smith DF, Galkina E, Ley K, Huo Y. GRO family chemokines are specialized for monocyte arrest from flow. American Journal of Physiology. Heart and Circulatory Physiology. 289: H1976-84. PMID 15937099 DOI: 10.1152/Ajpheart.00153.2005 |
0.338 |
|
2005 |
Stark MA, Huo Y, Burcin TL, Morris MA, Olson TS, Ley K. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity. 22: 285-94. PMID 15780986 DOI: 10.1016/J.Immuni.2005.01.011 |
0.727 |
|
2005 |
Rivera-Nieves J, Olson T, Bamias G, Bruce A, Solga M, Knight RF, Hoang S, Cominelli F, Ley K. L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestine. Journal of Immunology (Baltimore, Md. : 1950). 174: 2343-52. PMID 15699171 DOI: 10.4049/Jimmunol.174.4.2343 |
0.313 |
|
2005 |
Ley K, Deem TL. Oxidative modification of leukocyte adhesion. Immunity. 22: 5-7. PMID 15664154 DOI: 10.1016/J.Immuni.2005.01.002 |
0.341 |
|
2005 |
Klibanov A, Rychak J, Kaul S, Ley K, Lindner J. Fold-Carrying Particles: Improvement of Targeted Microbubble Attachment Academic Radiology. 12: S43-S44. DOI: 10.1016/J.Acra.2005.02.031 |
0.65 |
|
2004 |
Smith ML, Olson TS, Ley K. CXCR2- and E-selectin-induced neutrophil arrest during inflammation in vivo. The Journal of Experimental Medicine. 200: 935-9. PMID 15466624 DOI: 10.1084/Jem.20040424 |
0.36 |
|
2004 |
Huo Y, Zhao L, Hyman MC, Shashkin P, Harry BL, Burcin T, Forlow SB, Stark MA, Smith DF, Clarke S, Srinivasan S, Hedrick CC, Praticò D, Witztum JL, Nadler JL, ... ... Ley K, et al. Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice. Circulation. 110: 2024-31. PMID 15451785 DOI: 10.1161/01.Cir.0000143628.37680.F6 |
0.763 |
|
2004 |
Koszalka P, Ozüyaman B, Huo Y, Zernecke A, Flögel U, Braun N, Buchheiser A, Decking UK, Smith ML, Sévigny J, Gear A, Weber AA, Molojavyi A, Ding Z, Weber C, ... Ley K, et al. Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circulation Research. 95: 814-21. PMID 15358667 DOI: 10.1161/01.Res.0000144796.82787.6F |
0.351 |
|
2004 |
Dunne JL, Goobic AP, Acton ST, Ley K. A novel method to analyze leukocyte rolling behavior in vivo. Biological Procedures Online. 6: 173-179. PMID 15346173 DOI: 10.1251/Bpo87 |
0.691 |
|
2004 |
Olson TS, Bamias G, Naganuma M, Rivera-Nieves J, Burcin TL, Ross W, Morris MA, Pizarro TT, Ernst PB, Cominelli F, Ley K. Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease. The Journal of Clinical Investigation. 114: 389-98. PMID 15286805 DOI: 10.1172/Jci20855 |
0.326 |
|
2004 |
Gakidis MA, Cullere X, Olson T, Wilsbacher JL, Zhang B, Moores SL, Ley K, Swat W, Mayadas T, Brugge JS. Vav GEFs are required for beta2 integrin-dependent functions of neutrophils. The Journal of Cell Biology. 166: 273-82. PMID 15249579 DOI: 10.1083/Jcb.200404166 |
0.313 |
|
2004 |
Long DS, Smith ML, Pries AR, Ley K, Damiano ER. Microviscometry reveals reduced blood viscosity and altered shear rate and shear stress profiles in microvessels after hemodilution. Proceedings of the National Academy of Sciences of the United States of America. 101: 10060-5. PMID 15220478 DOI: 10.1073/Pnas.0402937101 |
0.301 |
|
2004 |
Ley K, Kansas GS. Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation. Nature Reviews. Immunology. 4: 325-35. PMID 15122198 DOI: 10.1038/Nri1351 |
0.323 |
|
2004 |
Takalkar AM, Klibanov AL, Rychak JJ, Lindner JR, Ley K. Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow. Journal of Controlled Release : Official Journal of the Controlled Release Society. 96: 473-82. PMID 15120903 DOI: 10.1016/J.Jconrel.2004.03.002 |
0.68 |
|
2004 |
Smith ML, Sperandio M, Galkina EV, Ley K. Autoperfused mouse flow chamber reveals synergistic neutrophil accumulation through P-selectin and E-selectin. Journal of Leukocyte Biology. 76: 985-93. PMID 15075351 DOI: 10.1189/Jlb.1003483 |
0.321 |
|
2004 |
Manka D, Forlow SB, Sanders JM, Hurwitz D, Bennett DK, Green SA, Ley K, Sarembock IJ. Critical role of platelet P-selectin in the response to arterial injury in apolipoprotein-E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1124-9. PMID 15072990 DOI: 10.1161/01.Atv.0000127619.04687.F4 |
0.725 |
|
2004 |
Fischer JJ, Huo Y, Bennett DK, Bevard M, Davis CJ, Ley K, Sarembock IJ. 1102-53 CX3CR1 gene disruption is not associated with decreased neointima formation after carotid wire injury in apolipoprotein-E deficient mice Journal of the American College of Cardiology. 43: A69. DOI: 10.1016/S0735-1097(04)90289-6 |
0.303 |
|
2003 |
Dunne JL, Collins RG, Beaudet AL, Ballantyne CM, Ley K. Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation. Journal of Immunology (Baltimore, Md. : 1950). 171: 6105-11. PMID 14634125 DOI: 10.4049/Jimmunol.171.11.6105 |
0.72 |
|
2003 |
Sperandio M, Smith ML, Forlow SB, Olson TS, Xia L, McEver RP, Ley K. P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venules. The Journal of Experimental Medicine. 197: 1355-63. PMID 12756271 DOI: 10.1084/Jem.20021854 |
0.34 |
|
2003 |
Phillips JW, Barringhaus KG, Sanders JM, Hesselbacher SE, Czarnik AC, Manka D, Vestweber D, Ley K, Sarembock IJ. Single injection of P-selectin or P-selectin glycoprotein ligand-1 monoclonal antibody blocks neointima formation after arterial injury in apolipoprotein E-deficient mice. Circulation. 107: 2244-9. PMID 12707243 DOI: 10.1161/01.Cir.0000065604.56839.18 |
0.736 |
|
2003 |
Thatte J, Dabak V, Williams MB, Braciale TJ, Ley K. LFA-1 is required for retention of effector CD8 T cells in mouse lungs. Blood. 101: 4916-22. PMID 12623847 DOI: 10.1182/Blood-2002-10-3159 |
0.341 |
|
2003 |
Shashkin P, Simpson D, Mishin V, Chesnutt B, Ley K. Expression of CXCL16 in human T cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 148-9. PMID 12524239 DOI: 10.1161/01.Atv.0000043906.61088.4B |
0.339 |
|
2003 |
Bachmann C, Klibanov AL, Cominelli F, Ley KF, Lindner JR, Pizarro TT. Targeting MAdCAM-1: A novel non-invasive diagnostic tool for therapeutic monitoring and the evaluation of active intestinal inflammation Gastroenterology. 124: A192. DOI: 10.1016/S0016-5085(03)80963-0 |
0.761 |
|
2002 |
Ellies LG, Sperandio M, Underhill GH, Yousif J, Smith M, Priatel JJ, Kansas GS, Ley K, Marth JD. Sialyltransferase specificity in selectin ligand formation. Blood. 100: 3618-25. PMID 12393657 DOI: 10.1182/Blood-2002-04-1007 |
0.34 |
|
2002 |
Forlow SB, White EJ, Thomas KL, Bagby GJ, Foley PL, Ley K. T cell requirement for development of chronic ulcerative dermatitis in E- and P-selectin-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 169: 4797-804. PMID 12391189 DOI: 10.4049/Jimmunol.169.9.4797 |
0.344 |
|
2002 |
Prorock AJ, Hafezi-Moghadam A, Laubach VE, Liao JK, Ley K. Vascular protection by estrogen in ischemia-reperfusion injury requires endothelial nitric oxide synthase. American Journal of Physiology. Heart and Circulatory Physiology. 284: H133-40. PMID 12388253 DOI: 10.1152/Ajpheart.00957.2001 |
0.345 |
|
2002 |
Forlow SB, Foley PL, Ley K. Severely reduced neutrophil adhesion and impaired host defense against fecal and commensal bacteria in CD18-/-P-selectin-/- double null mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1488-96. PMID 12374771 DOI: 10.1096/Fj.02-0230Com |
0.334 |
|
2002 |
Schober A, Manka D, Von Hundelshausen P, Huo Y, Hanrath P, Sarembock IJ, Ley K, Weber C. Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury Circulation. 106: 1523-1529. PMID 12234959 DOI: 10.1161/01.Cir.0000028590.02477.6F |
0.749 |
|
2002 |
Xia L, Sperandio M, Yago T, McDaniel JM, Cummings RD, Pearson-White S, Ley K, McEver RP. P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow. The Journal of Clinical Investigation. 109: 939-50. PMID 11927621 DOI: 10.1172/Jci14151 |
0.358 |
|
2002 |
Dunne JL, Ballantyne CM, Beaudet AL, Ley K. Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1. Blood. 99: 336-41. PMID 11756189 DOI: 10.1182/Blood.V99.1.336 |
0.699 |
|
2002 |
Ley K. Pathways and bottlenecks in the web of inflammatory adhesion molecules and chemoattractants. Immunologic Research. 24: 87-95. PMID 11485212 DOI: 10.1385/Ir:24:1:87 |
0.359 |
|
2001 |
Bradley Forlow S, Schurr JR, Kolls JK, Bagby GJ, Schwarzenberger PO, Ley K. Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice Blood. 98: 3309-3314. PMID 11719368 DOI: 10.1182/Blood.V98.12.3309 |
0.361 |
|
2001 |
Huo Y, Weber C, Forlow SB, Sperandio M, Thatte J, Mack M, Jung S, Littman DR, Ley K. The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium Journal of Clinical Investigation. 108: 1307-1314. PMID 11696575 DOI: 10.1172/Jci12877 |
0.4 |
|
2001 |
Singbartl K, Forlow SB, Ley K. Platelet, but not endothelial, P-selectin is critical for neutrophil-mediated acute postischemic renal failure The Faseb Journal. 15: 2337-2344. PMID 11689459 DOI: 10.1096/Fj.01-0199Com |
0.315 |
|
2001 |
Huo Y, Ley K. Adhesion molecules and atherogenesis Acta Physiologica Scandinavica. 173: 35-43. PMID 11678724 DOI: 10.1046/J.1365-201X.2001.00882.X |
0.416 |
|
2001 |
Ley K. Plugging the leaks. Nature Medicine. 7: 1105-6. PMID 11590428 DOI: 10.1038/Nm1001-1105 |
0.308 |
|
2001 |
Lysiak JJ, Turner SD, Nguyen QAT, Singbartl K, Ley K, Turner TT. Essential role of neutrophils in germ cell-specific apoptosis following ischemia/reperfusion injury of the mouse testis Biology of Reproduction. 65: 718-725. PMID 11514333 DOI: 10.1095/Biolreprod65.3.718 |
0.363 |
|
2001 |
Sperandio M, Forlow SB, Thatte J, Ellies LG, Marth JD, Ley K. Differential requirements for core2 glucosaminyltransferase for endothelial L-selectin ligand function in vivo Journal of Immunology. 167: 2268-2274. PMID 11490014 DOI: 10.4049/Jimmunol.167.4.2268 |
0.315 |
|
2001 |
Collins RG, Jung U, Ramirez M, Bullard DC, Hicks MJ, Smith CW, Ley K, Beaudet AL. Dermal and pulmonary inflammatory disease in E-selectin and P-selectin double-null mice is reduced in triple-selectin-null mice. Blood. 98: 727-35. PMID 11468173 DOI: 10.1182/Blood.V98.3.727 |
0.357 |
|
2001 |
Singbartl K, Thatte J, Smith ML, Wethmar K, Day K, Ley K. A CD2-green fluorescence protein-transgenic mouse reveals very late antigen-4-dependent CD8+ lymphocyte rolling in inflamed venules. Journal of Immunology (Baltimore, Md. : 1950). 166: 7520-6. PMID 11390506 DOI: 10.4049/Jimmunol.166.12.7520 |
0.312 |
|
2001 |
Sperandio M, Thatte A, Foy D, Ellies LG, Marth JD, Ley K. Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice Blood. 97: 3812-3819. PMID 11389021 DOI: 10.1182/Blood.V97.12.3812 |
0.348 |
|
2001 |
Ley K, Huo Y. VCAM-1 is critical in atherosclerosis Journal of Clinical Investigation. 107: 1209-1210. PMID 11375406 DOI: 10.1172/Jci13005 |
0.411 |
|
2001 |
Ley K. Functions of selectins. Results and Problems in Cell Differentiation. 33: 177-200. PMID 11190674 DOI: 10.1007/978-3-540-46410-5_10 |
0.367 |
|
2001 |
Manka D, Collins RG, Ley K, Beaudet AL, Sarembock IJ. Absence of p-selectin, but not intercellular adhesion molecule-1, attenuates neointimal growth after arterial injury in apolipoprotein e-deficient mice. Circulation. 103: 1000-5. PMID 11181476 DOI: 10.1161/01.Cir.103.7.1000 |
0.732 |
|
2001 |
Forlow SB, Ley K. Selectin-independent leukocyte rolling and adhesion in mice deficient in E-, P-, and L-selectin and ICAM-1 American Journal of Physiology-Heart and Circulatory Physiology. 280. PMID 11158961 DOI: 10.1152/Ajpheart.2001.280.2.H634 |
0.345 |
|
2000 |
Forlow SB, White EJ, Barlow SC, Feldman SH, Lu H, Bagby GJ, Beaudet AL, Bullard DC, Ley K. Severe inflammatory defect and reduced viability in CD18 and E-selectin double-mutant mice. The Journal of Clinical Investigation. 106: 1457-66. PMID 11120753 DOI: 10.1172/Jci10555 |
0.331 |
|
2000 |
Lindner JR, Kahn ML, Coughlin SR, Sambrano GR, Schauble E, Bernstein D, Foy D, Hafezi-Moghadam A, Ley K. Delayed onset of inflammation in protease-activated receptor-2-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 6504-10. PMID 11086091 DOI: 10.4049/Jimmunol.165.11.6504 |
0.386 |
|
2000 |
Foy DS, Ley K. Intercellular adhesion molecule-1 is required for chemoattractant-induced leukocyte adhesion in resting, but not inflamed, venules in vivo. Microvascular Research. 60: 249-260. PMID 11078641 DOI: 10.1006/Mvre.2000.2272 |
0.35 |
|
2000 |
Manka DR, Gilson W, Sarembock I, Ley K, Berr SS. Noninvasive in vivo magnetic resonance imaging of injury-induced neointima formation in the carotid artery of the apolipoprotein-E null mouse. Journal of Magnetic Resonance Imaging : Jmri. 12: 790-4. PMID 11050652 DOI: 10.1002/1522-2586(200011)12:5<790::Aid-Jmri19>3.0.Co;2-6 |
0.715 |
|
2000 |
Singbartl K, Ley K. Protection from ischemia-reperfusion induced severe acute renal failure by blocking E-selectin. Critical Care Medicine. 28: 2507-2514. PMID 10921586 DOI: 10.1097/00003246-200007000-00053 |
0.33 |
|
2000 |
Lindner JR, Dayton PA, Coggins MP, Ley K, Song J, Ferrara K, Kaul S. Noninvasive imaging of inflammation by ultrasound detection of Phagocytosed microbubbles Circulation. 102: 531-538. PMID 10920065 DOI: 10.1161/01.Cir.102.5.531 |
0.342 |
|
2000 |
Huo Y, Hafezi-Moghadam A, Ley K. Role of vascular cell adhesion molecule-1 and fibronectin connecting segment-1 in monocyte rolling and adhesion on early atherosclerotic lesions. Circulation Research. 87: 153-9. PMID 10904000 DOI: 10.1161/01.Res.87.2.153 |
0.37 |
|
2000 |
Kunkel EJ, Dunne JL, Ley K. Leukocyte arrest during cytokine-dependent inflammation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 164: 3301-8. PMID 10706723 DOI: 10.4049/Jimmunol.164.6.3301 |
0.709 |
|
2000 |
Lindner JR, Coggins MP, Kaul S, Klibanov AL, Brandenburger GH, Ley K. Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin- and complement- mediated adherence to activated leukocytes Circulation. 101: 668-675. PMID 10673260 DOI: 10.1161/01.Cir.101.6.668 |
0.324 |
|
1999 |
Manka DR, Wiegman P, Din S, Sanders JM, Green SA, Gimple LW, Ragosta M, Powers ER, Ley K, Sarembock IJ. Arterial injury increases expression of inflammatory adhesion molecules in the carotid arteries of apolipoprotein-E-deficient mice. Journal of Vascular Research. 36: 372-8. PMID 10559677 DOI: 10.1159/000025676 |
0.748 |
|
1999 |
Kamochi M, Kamochi F, Kim YB, Sawh S, Sanders JM, Sarembock I, Green S, Young JS, Ley K, Fu SM, Rose CE. P-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver. The American Journal of Physiology. 277: L310-9. PMID 10444525 DOI: 10.1152/Ajplung.1999.277.2.L310 |
0.347 |
|
1999 |
Ramos CL, Huo Y, Jung U, Ghosh S, Manka DR, Sarembock IJ, Ley K. Direct demonstration of P-selectin- and VCAM-1-dependent mononuclear cell rolling in early atherosclerotic lesions of apolipoprotein E-deficient mice. Circulation Research. 84: 1237-44. PMID 10364560 DOI: 10.1161/01.Res.84.11.1237 |
0.758 |
|
1999 |
Hafezi-Moghadam A, Ley K. Relevance of L-selectin shedding for leukocyte rolling in vivo. The Journal of Experimental Medicine. 189: 939-48. PMID 10075977 DOI: 10.1084/Jem.189.6.939 |
0.33 |
|
1999 |
Bishop GG, Wiegman P, McNamara C, Din S, Sanders J, Hesselbacher S, Feldman M, McPherson JA, Humphries JE, Hammarskjold M, Gimple LW, Ragosta M, Powers ER, Dickek D, Owens GK, ... ... Ley K, et al. Selected Comments on and Replies to the Article Journal of Vascular Research. 36: 352-352. DOI: 10.1159/000025673 |
0.68 |
|
1999 |
Bishop GG, Wiegman P, McNamara C, Din S, Sanders J, Hesselbacher S, Feldman M, McPherson JA, Humphries JE, Hammarskjold M, Gimple LW, Ragosta M, Powers ER, Dickek D, Owens GK, ... ... Ley K, et al. Editorial: The JVR Internet Discussion Forum Journal of Vascular Research. 36: 343-343. DOI: 10.1159/000025671 |
0.672 |
|
1998 |
Jung U, Norman KE, Scharffetter-Kochanek K, Beaudet AL, Ley K. Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo. The Journal of Clinical Investigation. 102: 1526-33. PMID 9788965 DOI: 10.1172/Jci119893 |
0.371 |
|
1998 |
Aigner S, Ramos CL, Hafezi-Moghadam A, Lawrence MB, Friederichs J, Altevogt P, Ley K. CD24 mediates rolling of breast carcinoma cells on P-selectin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1241-51. PMID 9737727 DOI: 10.1096/Fasebj.12.12.1241 |
0.31 |
|
1998 |
Ley K, Allietta M, Bullard DC, Morgan S. Importance of E-selectin for firm leukocyte adhesion in vivo. Circulation Research. 83: 287-94. PMID 9710121 DOI: 10.1161/01.Res.83.3.287 |
0.373 |
|
1998 |
Scharffetter-Kochanek K, Lu H, Norman K, van Nood N, Munoz F, Grabbe S, McArthur M, Lorenzo I, Kaplan S, Ley K, Smith CW, Montgomery CA, Rich S, Beaudet AL. Spontaneous skin ulceration and defective T cell function in CD18 null mice. The Journal of Experimental Medicine. 188: 119-31. PMID 9653089 DOI: 10.1084/Jem.188.1.119 |
0.318 |
|
1998 |
Steeber DA, Campbell MA, Basit A, Ley K, Tedder TF. Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression. Proceedings of the National Academy of Sciences of the United States of America. 95: 7562-7. PMID 9636189 DOI: 10.1073/Pnas.95.13.7562 |
0.533 |
|
1998 |
Jung U, Ramos CL, Bullard DC, Ley K. Gene-targeted mice reveal importance of L-selectin-dependent rolling for neutrophil adhesion. The American Journal of Physiology. 274: H1785-91. PMID 9612391 DOI: 10.1152/Ajpheart.1998.274.5.H1785 |
0.363 |
|
1998 |
Kunkel EJ, Chomas JE, Ley K. Role of primary and secondary capture for leukocyte accumulation in vivo Circulation Research. 82: 30-38. PMID 9440702 DOI: 10.1161/01.Res.82.1.30 |
0.315 |
|
1998 |
Norman KE, Anderson GP, Kolb HC, Ley K, Ernst B. Sialyl Lewisx (sLex) and an sLexMimetic, CGP69669A, Disrupt E-Selectin–Dependent Leukocyte Rolling In Vivo Blood. 91: 475-483. DOI: 10.1182/Blood.V91.2.475.475_475_483 |
0.337 |
|
1997 |
Morgan SJ, Moore MW, Cacalano G, Ley K. Brief communication: Reduced leukocyte adhesion response and absence of slow leukocyte rolling in interleukin-8 receptor-deficient mice Microvascular Research. 54: 188-191. PMID 9327391 DOI: 10.1006/Mvre.1997.2029 |
0.319 |
|
1997 |
Kunkel EJ, Jung U, Ley K. TNF-alpha induces selectin-mediated leukocyte rolling in mouse cremaster muscle arterioles. The American Journal of Physiology. 272: H1391-400. PMID 9087616 DOI: 10.1152/Ajpheart.1997.272.3.H1391 |
0.347 |
|
1997 |
Lawrence MB, Kansas GS, Kunkel EJ, Ley K. Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E) The Journal of Cell Biology. 136: 717-27. PMID 9024700 DOI: 10.1083/Jcb.136.3.717 |
0.331 |
|
1997 |
Damiano ER, Westheider J, Tözeren A, Ley K. Variation in the velocity, deformation, and adhesion energy density of leukocytes rolling within venules. Circulation Research. 79: 1122-30. PMID 8943950 DOI: 10.1161/01.Res.79.6.1122 |
0.314 |
|
1997 |
Borges E, Eytner R, Moll T, Steegmaier M, Campbell MA, Ley K, Mossmann H, Vestweber D. The P-Selectin Glycoprotein Ligand-1 Is Important for Recruitment of Neutrophils Into Inflamed Mouse Peritoneum Blood. 90: 1934-1942. DOI: 10.1182/Blood.V90.5.1934 |
0.317 |
|
1997 |
Zakrzewicz A, Gräfe M, Terbeek D, Bongrazio M, Auch-Schwelk W, Walzog B, Graf K, Fleck E, Ley K, Gaehtgens P. L-Selectin–Dependent Leukocyte Adhesion to Microvascular But Not to Macrovascular Endothelial Cells of the Human Coronary System Blood. 89: 3228-3235. DOI: 10.1182/Blood.V89.9.3228 |
0.328 |
|
1997 |
Ramos CL, Kunkel EJ, Lawrence MB, Jung U, Vestweber D, Bosse R, McIntyre KW, Gillooly KM, Norton CR, Wolitzky BA, Ley K. Differential Effect of E-Selectin Antibodies on Neutrophil Rolling and Recruitment to Inflammatory Sites Blood. 89: 3009-3018. DOI: 10.1182/Blood.V89.8.3009 |
0.331 |
|
1996 |
Jung U, Bullard DC, Tedder TF, Ley K. Velocity differences between L- and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo. The American Journal of Physiology. 271: H2740-7. PMID 8997339 DOI: 10.1152/Ajpheart.1996.271.6.H2740 |
0.332 |
|
1996 |
Kunkel EJ, Ley K. Distinct phenotype of E-selectin-deficient mice: E-selectin is required for slow leukocyte rolling in vivo Circulation Research. 79: 1196-1204. PMID 8943958 DOI: 10.1161/01.Res.79.6.1196 |
0.364 |
|
1996 |
Kunkel EJ, Jung U, Bullard DC, Norman KE, Wolitzky BA, Vestweber D, Beaudet AL, Ley K. Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1. The Journal of Experimental Medicine. 183: 57-65. PMID 8551244 DOI: 10.1084/Jem.183.1.57 |
0.381 |
|
1996 |
Ley K. Molecular mechanisms of leukocyte recruitment in the inflammatory process Cardiovascular Research. 32: 733-742. DOI: 10.1016/S0008-6363(96)00066-1 |
0.364 |
|
1995 |
Norman K, Moore K, McEver R, Ley K. Leukocyte rolling in vivo is mediated by P-selectin glycoprotein ligand- 1 Blood. 86: 4417-4421. DOI: 10.1182/Blood.V86.12.4417.Bloodjournal86124417 |
0.356 |
|
1995 |
Ley K, Zakrzewicz A, Hanski C, Stoolman L, Kansas G. Sialylated O-glycans and L-selectin sequentially mediate myeloid cell rolling in vivo Blood. 85: 3727-3735. DOI: 10.1182/Blood.V85.12.3727.Bloodjournal85123727 |
0.307 |
|
1994 |
Ley K. Histamine can induce leukocyte rolling in rat mesenteric venules. American Journal of Physiology-Heart and Circulatory Physiology. 267. PMID 7522403 DOI: 10.1152/Ajpheart.1994.267.3.H1017 |
0.311 |
|
1993 |
Ley K, Tedder TF, Kansas GS. L-selectin can mediate leukocyte rolling in untreated mesenteric venules in vivo independent of E- or P-selectin Blood. 82: 1632-1638. DOI: 10.1182/Blood.V82.5.1632.1632 |
0.312 |
|
1992 |
Ley K. Leukocyte adhesion to vascular endothelium. Journal of Reconstructive Microsurgery. 8: 495-503. PMID 1453376 DOI: 10.1055/S-2007-1006736 |
0.327 |
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1992 |
Ley K, Gaehtgens P, Spanel-Borowski K. Differential adhesion of granulocytes to five distinct phenotypes of cultured microvascular endothelial cells. Microvascular Research. 43: 119-133. PMID 1374829 DOI: 10.1016/0026-2862(92)90011-D |
0.356 |
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