| Year |
Citation |
Score |
| 2015 |
Jiang X, Nevins JR, Shats I, Chi JT. E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program. Plos One. 10: e0127951. PMID 26039627 DOI: 10.1371/Journal.Pone.0127951 |
0.416 |
|
| 2014 |
Dong P, Maddali MV, Srimani JK, Thélot F, Nevins JR, Mathey-Prevot B, You L. Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control. Nature Communications. 5: 4750. PMID 25175461 DOI: 10.1038/Ncomms5750 |
0.394 |
|
| 2013 |
Shats I, Gatza ML, Liu B, Angus SP, You L, Nevins JR. FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function. Cancer Research. 73: 6056-67. PMID 23966291 DOI: 10.1158/0008-5472.Can-13-0453 |
0.441 |
|
| 2013 |
Liu B, Shats I, Angus SP, Gatza ML, Nevins JR. Interaction of E2F7 transcription factor with E2F1 and C-terminal-binding protein (CtBP) provides a mechanism for E2F7-dependent transcription repression. The Journal of Biological Chemistry. 288: 24581-9. PMID 23853115 DOI: 10.1074/Jbc.M113.467506 |
0.453 |
|
| 2013 |
Keenan MM, Liu B, Wu J, Cyr D, Lucas J, Nevins J, Kim SY, Chi J. Abstract A18: Genetic elements of cancer cell survival in tumor microenvironment stresses Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A18 |
0.362 |
|
| 2012 |
Leung JY, Nevins JR. E2F6 associates with BRG1 in transcriptional regulation. Plos One. 7: e47967. PMID 23082233 DOI: 10.1371/Journal.Pone.0047967 |
0.455 |
|
| 2012 |
Riedel RF, Porrello A, Pontzer E, Chenette EJ, Hsu DS, Balakumaran B, Potti A, Nevins J, Febbo PC. Retraction in part: A genomic approach to identify molecular pathways associated with chemotherapy resistance. Molecular Cancer Therapeutics. 11: 1214-5. PMID 22461660 DOI: 10.1158/1535-7163.Mct-12-0210 |
0.316 |
|
| 2012 |
Angus SP, Nevins JR. A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest. Oncogene. 31: 4709-17. PMID 22249253 DOI: 10.1038/Onc.2011.622 |
0.423 |
|
| 2012 |
Leung JY, Andrechek ER, Cardiff RD, Nevins JR. Heterogeneity in MYC-induced mammary tumors contributes to escape from oncogene dependence. Oncogene. 31: 2545-54. PMID 21996730 DOI: 10.1038/Onc.2011.433 |
0.33 |
|
| 2012 |
Friedman DR, Rempel RE, Jiang X, Nevins JR. Modeling Variation in the Human Lymphoma Microenvironment with the Eμ-Myc Mouse Model Blood. 120: 789-789. DOI: 10.1182/Blood.V120.21.789.789 |
0.324 |
|
| 2011 |
Chang JT, Gatza ML, Lucas JE, Barry WT, Vaughn P, Nevins JR. SIGNATURE: a workbench for gene expression signature analysis. Bmc Bioinformatics. 12: 443. PMID 22078435 DOI: 10.1186/1471-2105-12-443 |
0.324 |
|
| 2011 |
Wong JV, Dong P, Nevins JR, Mathey-Prevot B, You L. Network calisthenics: control of E2F dynamics in cell cycle entry. Cell Cycle (Georgetown, Tex.). 10: 3086-94. PMID 21900750 DOI: 10.4161/Cc.10.18.17350 |
0.343 |
|
| 2011 |
LaBreche HG, Meadows SK, Nevins JR, Chute JP. Peripheral blood signatures of lead exposure. Plos One. 6: e23043. PMID 21829687 DOI: 10.1371/Journal.Pone.0023043 |
0.743 |
|
| 2011 |
LaBreche HG, Nevins JR, Huang E. Integrating factor analysis and a transgenic mouse model to reveal a peripheral blood predictor of breast tumors. Bmc Medical Genomics. 4: 61. PMID 21781289 DOI: 10.1186/1755-8794-4-61 |
0.746 |
|
| 2011 |
Freedman JA, Augustine CK, Selim AM, Holshausen KC, Wei Z, Tsamis KA, Hsu DS, Dressman HK, Barry WT, Tyler DS, Nevins JR. A methodology for utilization of predictive genomic signatures in FFPE samples. Bmc Medical Genomics. 4: 58. PMID 21745407 DOI: 10.1186/1755-8794-4-58 |
0.328 |
|
| 2011 |
Freedman JA, Tyler DS, Nevins JR, Augustine CK. Use of gene expression and pathway signatures to characterize the complexity of human melanoma. The American Journal of Pathology. 178: 2513-22. PMID 21641377 DOI: 10.1016/J.Ajpath.2011.02.037 |
0.345 |
|
| 2011 |
Wong JV, Yao G, Nevins JR, You L. Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells. Methods in Enzymology. 497: 221-37. PMID 21601089 DOI: 10.1016/B978-0-12-385075-1.00010-X |
0.341 |
|
| 2011 |
Yao G, Tan C, West M, Nevins JR, You L. Origin of bistability underlying mammalian cell cycle entry. Molecular Systems Biology. 7: 485. PMID 21525871 DOI: 10.1038/Msb.2011.19 |
0.35 |
|
| 2011 |
Wong JV, Yao G, Nevins JR, You L. Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC. Molecular Cell. 41: 275-85. PMID 21292160 DOI: 10.1016/J.Molcel.2011.01.014 |
0.363 |
|
| 2011 |
Shats I, Gatza ML, Chang JT, Mori S, Wang J, Rich J, Nevins JR. Using a stem cell-based signature to guide therapeutic selection in cancer. Cancer Research. 71: 1772-80. PMID 21169407 DOI: 10.1158/0008-5472.Can-10-1735 |
0.317 |
|
| 2011 |
Friedman DR, Nevins JR. Genomic Heterogeneity in B-Cell Malignancies, Blood. 118: 3465-3465. DOI: 10.1182/Blood.V118.21.3465.3465 |
0.328 |
|
| 2010 |
Lee TJ, Yao G, Bennett DC, Nevins JR, You L. Stochastic E2F activation and reconciliation of phenomenological cell-cycle models. Plos Biology. 8. PMID 20877711 DOI: 10.1371/Journal.Pbio.1000488 |
0.311 |
|
| 2010 |
Andrechek ER, Nevins JR. Mouse models of cancers: opportunities to address heterogeneity of human cancer and evaluate therapeutic strategies. Journal of Molecular Medicine (Berlin, Germany). 88: 1095-100. PMID 20574808 DOI: 10.1007/S00109-010-0644-Z |
0.306 |
|
| 2010 |
Kim JW, Mori S, Nevins JR. Myc-induced microRNAs integrate Myc-mediated cell proliferation and cell fate. Cancer Research. 70: 4820-8. PMID 20516112 DOI: 10.1158/0008-5472.Can-10-0659 |
0.345 |
|
| 2010 |
Barry WT, Kernagis DN, Dressman HK, Griffis RJ, Hunter JD, Olson JA, Marks JR, Ginsburg GS, Marcom PK, Nevins JR, Geradts J, Datto MB. Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 2198-206. PMID 20368555 DOI: 10.1200/Jco.2009.26.7245 |
0.322 |
|
| 2010 |
Gatza ML, Lucas JE, Barry WT, Kim JW, Wang Q, Crawford MD, Datto MB, Kelley M, Mathey-Prevot B, Potti A, Nevins JR. A pathway-based classification of human breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 107: 6994-9. PMID 20335537 DOI: 10.1073/Pnas.0912708107 |
0.362 |
|
| 2010 |
Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP. Multimodal regulation of E2F1 gene expression by progestins. Molecular and Cellular Biology. 30: 1866-77. PMID 20123965 DOI: 10.1128/Mcb.01060-09 |
0.416 |
|
| 2010 |
VanDeusen JB, Osada T, Morse M, Clary BM, Lyerly HK, Nevins JR, Clay TM, Febbo PG, Hsu SD. Use of gene expression signatures to predict in vivo sensitivity of human metastatic colorectal cancer to chemotherapy and to identify novel drug combinations. Journal of Clinical Oncology. 28: e14064-e14064. DOI: 10.1200/Jco.2010.28.15_Suppl.E14064 |
0.307 |
|
| 2010 |
Nevins JR. Abstract IA3-2: Utilization of genomic signatures to guide therapeutic decisions Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-Ia3-2 |
0.329 |
|
| 2009 |
Andrechek ER, Cardiff RD, Chang JT, Gatza ML, Acharya CR, Potti A, Nevins JR. Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential. Proceedings of the National Academy of Sciences of the United States of America. 106: 16387-92. PMID 19805309 DOI: 10.1073/Pnas.0901250106 |
0.357 |
|
| 2009 |
Rempel RE, Mori S, Gasparetto M, Glozak MA, Andrechek ER, Adler SB, Laakso NM, Lagoo AS, Storms R, Smith C, Nevins JR. A role for E2F activities in determining the fate of Myc-induced lymphomagenesis. Plos Genetics. 5: e1000640. PMID 19749980 DOI: 10.1371/Journal.Pgen.1000640 |
0.348 |
|
| 2009 |
Mori S, Chang JT, Andrechek ER, Potti A, Nevins JR. Utilization of genomic signatures to identify phenotype-specific drugs. Plos One. 4: e6772. PMID 19714244 DOI: 10.1371/Journal.Pone.0006772 |
0.332 |
|
| 2009 |
Bild AH, Parker JS, Gustafson AM, Acharya CR, Hoadley KA, Anders C, Marcom PK, Carey LA, Potti A, Nevins JR, Perou CM. An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer. Breast Cancer Research : Bcr. 11: R55. PMID 19638211 DOI: 10.1186/Bcr2344 |
0.315 |
|
| 2009 |
Anguiano A, Tuchman SA, Acharya C, Salter K, Gasparetto C, Zhan F, Dhodapkar M, Nevins J, Barlogie B, Shaughnessy JD, Potti A. Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 4197-203. PMID 19636021 DOI: 10.1200/Jco.2008.19.1916 |
0.351 |
|
| 2009 |
Freedman JA, Chang JT, Jakoi L, Nevins JR. A combinatorial mechanism for determining the specificity of E2F activation and repression. Oncogene. 28: 2873-81. PMID 19543322 DOI: 10.1038/Onc.2009.153 |
0.397 |
|
| 2009 |
Mori S, Chang JT, Andrechek ER, Matsumura N, Baba T, Yao G, Kim JW, Gatza M, Murphy S, Nevins JR. Anchorage-independent cell growth signature identifies tumors with metastatic potential Oncogene. 28: 2796-2805. PMID 19483725 DOI: 10.1038/Onc.2009.139 |
0.374 |
|
| 2009 |
Chang JT, Carvalho C, Mori S, Bild AH, Gatza ML, Wang Q, Lucas JE, Potti A, Febbo PG, West M, Nevins JR. A genomic strategy to elucidate modules of oncogenic pathway signaling networks. Molecular Cell. 34: 104-14. PMID 19362539 DOI: 10.1016/J.Molcel.2009.02.030 |
0.32 |
|
| 2009 |
Hsu DS, Acharya CR, Balakumaran BS, Riedel RF, Kim MK, Stevenson M, Tuchman S, Mukherjee S, Barry W, Dressman HK, Nevins JR, Powers S, Mu D, Potti A. Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 106: 5312-7. PMID 19279207 DOI: 10.1073/Pnas.0900827106 |
0.329 |
|
| 2009 |
Hallstrom TC, Nevins JR. Balancing the decision of cell proliferation and cell fate. Cell Cycle (Georgetown, Tex.). 8: 532-5. PMID 19182518 DOI: 10.4161/Cc.8.4.7609 |
0.453 |
|
| 2008 |
Carvalho CM, Chang J, Lucas JE, Nevins JR, Wang Q, West M. High-Dimensional Sparse Factor Modeling: Applications in Gene Expression Genomics. Journal of the American Statistical Association. 103: 1438-1456. PMID 21218139 DOI: 10.1198/016214508000000869 |
0.342 |
|
| 2008 |
Chen JL, Lucas JE, Schroeder T, Mori S, Wu J, Nevins J, Dewhirst M, West M, Chi JT. The genomic analysis of lactic acidosis and acidosis response in human cancers. Plos Genetics. 4: e1000293. PMID 19057672 DOI: 10.1371/Journal.Pgen.1000293 |
0.352 |
|
| 2008 |
Garman KS, Acharya CR, Edelman E, Grade M, Gaedcke J, Sud S, Barry W, Diehl AM, Provenzale D, Ginsburg GS, Ghadimi BM, Ried T, Nevins JR, Mukherjee S, Hsu D, et al. A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. Proceedings of the National Academy of Sciences of the United States of America. 105: 19432-7. PMID 19050079 DOI: 10.1073/Pnas.0806674105 |
0.318 |
|
| 2008 |
Mori S, Rempel RE, Chang JT, Yao G, Lagoo AS, Potti A, Bild A, Nevins JR. Utilization of pathway signatures to reveal distinct types of B lymphoma in the Emicro-myc model and human diffuse large B-cell lymphoma. Cancer Research. 68: 8525-34. PMID 18922927 DOI: 10.1158/0008-5472.Can-08-1329 |
0.331 |
|
| 2008 |
Riedel RF, Porrello A, Pontzer E, Chenette EJ, Hsu DS, Balakumaran B, Potti A, Nevins J, Febbo PG. A genomic approach to identify molecular pathways associated with chemotherapy resistance. Molecular Cancer Therapeutics. 7: 3141-9. PMID 18852117 DOI: 10.1158/1535-7163.Mct-08-0642 |
0.309 |
|
| 2008 |
Anguiano A, Nevins JR, Potti A. Toward the individualization of lung cancer therapy. Cancer. 113: 1760-7. PMID 18800387 DOI: 10.1002/Cncr.23644 |
0.301 |
|
| 2008 |
Andrechek ER, Mori S, Rempel RE, Chang JT, Nevins JR. Patterns of cell signaling pathway activation that characterize mammary development. Development (Cambridge, England). 135: 2403-13. PMID 18550711 DOI: 10.1242/Dev.019018 |
0.356 |
|
| 2008 |
Lee T, Yao G, Nevins J, You L. Sensing and integration of Erk and PI3K signals by Myc. Plos Computational Biology. 4: e1000013. PMID 18463697 DOI: 10.1371/Journal.Pcbi.1000013 |
0.345 |
|
| 2008 |
Meadows SK, Dressman HK, Muramoto GG, Himburg H, Salter A, Wei Z, Ginsburg GS, Ginsburg G, Chao NJ, Nevins JR, Chute JP. Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. Plos One. 3: e1912. PMID 18382685 DOI: 10.1371/Journal.Pone.0001912 |
0.311 |
|
| 2008 |
Salter KH, Acharya CR, Walters KS, Redman R, Anguiano A, Garman KS, Anders CK, Mukherjee S, Dressman HK, Barry WT, Marcom KP, Olson J, Nevins JR, Potti A. An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer. Plos One. 3: e1908. PMID 18382681 DOI: 10.1371/Journal.Pone.0001908 |
0.315 |
|
| 2008 |
Xu M, Kao MC, Nunez-Iglesias J, Nevins JR, West M, Zhou XJ. An integrative approach to characterize disease-specific pathways and their coordination: a case study in cancer. Bmc Genomics. 9: S12. PMID 18366601 DOI: 10.1186/1471-2164-9-S1-S12 |
0.327 |
|
| 2008 |
Yao G, Lee TJ, Mori S, Nevins JR, You L. A bistable Rb-E2F switch underlies the restriction point. Nature Cell Biology. 10: 476-82. PMID 18364697 DOI: 10.1038/Ncb1711 |
0.32 |
|
| 2008 |
Leung JY, Ehmann GL, Giangrande PH, Nevins JR. A role for Myc in facilitating transcription activation by E2F1. Oncogene. 27: 4172-9. PMID 18345030 DOI: 10.1038/Onc.2008.55 |
0.472 |
|
| 2008 |
Potti A, Nevins JR. Utilization of genomic signatures to direct use of primary chemotherapy. Current Opinion in Genetics & Development. 18: 62-7. PMID 18339540 DOI: 10.1016/J.Gde.2008.01.018 |
0.321 |
|
| 2008 |
Hallstrom TC, Mori S, Nevins JR. An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. Cancer Cell. 13: 11-22. PMID 18167336 DOI: 10.1016/J.Ccr.2007.11.031 |
0.366 |
|
| 2008 |
Friedman D, Weinberg JB, Bond KM, Volkheimer AD, Chen Y, Nevins JR. Identification of Therapeutic Targets for Chronic Lymphocytic Leukemia in the Relapsed and Refractory Setting. Blood. 112: 2068-2068. DOI: 10.1182/Blood.V112.11.2068.2068 |
0.316 |
|
| 2007 |
Nevins JR. New breast cancer genes-discovery at the intersection of complex data sets. Cancer Cell. 12: 497-9. PMID 18068627 DOI: 10.1016/J.Ccr.2007.11.019 |
0.331 |
|
| 2007 |
Garman KS, Nevins JR, Potti A. Genomic strategies for personalized cancer therapy. Human Molecular Genetics. 16: R226-32. PMID 17911165 DOI: 10.1093/Hmg/Ddm184 |
0.315 |
|
| 2007 |
Giangrande PH, Zhang J, Tanner A, Eckhart AD, Rempel RE, Andrechek ER, Layzer JM, Keys JR, Hagen PO, Nevins JR, Koch WJ, Sullenger BA. Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. 104: 12988-93. PMID 17652516 DOI: 10.1073/Pnas.0704754104 |
0.359 |
|
| 2007 |
Nevins JR, Potti A. Mining gene expression profiles: expression signatures as cancer phenotypes. Nature Reviews. Genetics. 8: 601-9. PMID 17607306 DOI: 10.1038/Nrg2137 |
0.325 |
|
| 2007 |
Dressman HK, Berchuck A, Chan G, Zhai J, Bild A, Sayer R, Cragun J, Clarke J, Whitaker RS, Li L, Gray J, Marks J, Ginsburg GS, Potti A, West M, ... Nevins JR, et al. An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 517-25. PMID 17290060 DOI: 10.1200/Jco.2006.06.3743 |
0.322 |
|
| 2007 |
Kong LJ, Chang JT, Bild AH, Nevins JR. Compensation and specificity of function within the E2F family. Oncogene. 26: 321-7. PMID 16909124 DOI: 10.1038/Sj.Onc.1209817 |
0.421 |
|
| 2007 |
Riedel RF, Porrello A, Chenette E, Potti A, Nevins JR, Febbo PG. A genomic approach to identify mechanisms associated with chemotherapy resistance Journal of Clinical Oncology. 25: 2534-2534. DOI: 10.1200/Jco.2007.25.18_Suppl.2534 |
0.325 |
|
| 2007 |
Anguiano A, Mori S, Chang J, Vlahovic V, Kelley MJ, Ginsburg G, Dressman H, Nevins JR, Potti A. A genomic signature of chemotherapeutic multidrug resistance provides a rational approach to identify patients for targeted therapy in advanced solid tumors Journal of Clinical Oncology. 25: 10613-10613. DOI: 10.1200/Jco.2007.25.18_Suppl.10613 |
0.339 |
|
| 2007 |
Anguiano A, Acharya C, Salter K, McCluskey D, Gasperetto C, Zhan F, Dhodapkar M, Nevins J, Barlogie B, Shaughnessy JD, Potti A. Gene Expression Profiles for Prognosis in MGUS, Coupled with Signatures of Oncogenic Pathway Deregulation Provide a Novel Approach for Selection of Molecular Targets in Multiple Myeloma. Blood. 110: 655-655. DOI: 10.1182/Blood.V110.11.655.655 |
0.385 |
|
| 2007 |
Friedman DR, Weinberg JB, Potti A, Volkheimer AD, Bond KM, Chen Y, Jiang N, Moore JO, Gockerman JP, Diehl LF, Decastro CM, Nevins JR. A Genomic Strategy To Refine Prognosis and Predict Response to Therapy in Chronic Lymphocytic Leukemia. Blood. 110: 3096-3096. DOI: 10.1182/Blood.V110.11.3096.3096 |
0.329 |
|
| 2006 |
Lancaster JM, Dressman HK, Clarke JP, Sayer RA, Martino MA, Cragun JM, Henriott AH, Gray J, Sutphen R, Elahi A, Whitaker RS, West M, Marks JR, Nevins JR, Berchuck A. Identification of genes associated with ovarian cancer metastasis using microarray expression analysis. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 16: 1733-45. PMID 17009964 DOI: 10.1111/J.1525-1438.2006.00660.X |
0.361 |
|
| 2006 |
Cheng SH, Horng CF, West M, Huang E, Pittman J, Tsou MH, Dressman H, Chen CM, Tsai SY, Jian JJ, Liu MC, Nevins JR, Huang AT. Genomic prediction of locoregional recurrence after mastectomy in breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 4594-602. PMID 17008701 DOI: 10.1200/Jco.2005.02.5676 |
0.325 |
|
| 2006 |
Bild AH, Potti A, Nevins JR. Linking oncogenic pathways with therapeutic opportunities. Nature Reviews. Cancer. 6: 735-41. PMID 16915294 DOI: 10.1038/Nrc1976 |
0.349 |
|
| 2006 |
West M, Ginsburg GS, Huang AT, Nevins JR. Embracing the complexity of genomic data for personalized medicine. Genome Research. 16: 559-66. PMID 16651662 DOI: 10.1101/Gr.3851306 |
0.303 |
|
| 2006 |
Kong LJ, Meloni AR, Nevins JR. The Rb-related p130 protein controls telomere lengthening through an interaction with a Rad50-interacting protein, RINT-1. Molecular Cell. 22: 63-71. PMID 16600870 DOI: 10.1016/J.Molcel.2006.02.016 |
0.777 |
|
| 2006 |
Hallstrom TC, Nevins JR. Jab1 is a specificity factor for E2F1-induced apoptosis. Genes & Development. 20: 613-23. PMID 16481464 DOI: 10.1101/Gad.1345006 |
0.404 |
|
| 2006 |
Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, Joshi MB, Harpole D, Lancaster JM, Berchuck A, Olson JA, Marks JR, Dressman HK, West M, Nevins JR. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature. 439: 353-7. PMID 16273092 DOI: 10.1038/Nature04296 |
0.376 |
|
| 2005 |
Meloni AR, Lai CH, Yao TP, Nevins JR. A mechanism of COOH-terminal binding protein-mediated repression. Molecular Cancer Research : McR. 3: 575-83. PMID 16254191 DOI: 10.1158/1541-7786.Mcr-05-0088 |
0.79 |
|
| 2005 |
Black EP, Hallstrom T, Dressman HK, West M, Nevins JR. Distinctions in the specificity of E2F function revealed by gene expression signatures. Proceedings of the National Academy of Sciences of the United States of America. 102: 15948-53. PMID 16249342 DOI: 10.1073/Pnas.0504300102 |
0.468 |
|
| 2005 |
Rich JN, Hans C, Jones B, Iversen ES, McLendon RE, Rasheed BK, Dobra A, Dressman HK, Bigner DD, Nevins JR, West M. Gene expression profiling and genetic markers in glioblastoma survival. Cancer Research. 65: 4051-8. PMID 15899794 DOI: 10.1158/0008-5472.Can-04-3936 |
0.34 |
|
| 2005 |
Berchuck A, Iversen ES, Lancaster JM, Pittman J, Luo J, Lee P, Murphy S, Dressman HK, Febbo PG, West M, Nevins JR, Marks JR. Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3686-96. PMID 15897565 DOI: 10.1158/1078-0432.Ccr-04-2398 |
0.305 |
|
| 2005 |
Zhu W, Giangrande PH, Nevins JR. Temporal control of cell cycle gene expression mediated by E2F transcription factors. Cell Cycle (Georgetown, Tex.). 4: 633-6. PMID 15876877 DOI: 10.4161/Cc.4.5.1650 |
0.456 |
|
| 2005 |
Delong M, Yao G, Wang Q, Dobra A, Black EP, Chang JT, Bild A, West M, Nevins JR, Dressman H. DIG--a system for gene annotation and functional discovery. Bioinformatics (Oxford, England). 21: 2957-9. PMID 15870167 DOI: 10.1093/Bioinformatics/Bti467 |
0.326 |
|
| 2005 |
Potti A, Bild A, Lewis DA, Dressman H, Nevins JR, Ortel TL. Peripheral Blood Mononuclear Cell Derived Gene Expression Patterns Identify Clinical Phenotypes and Predict Thrombotic Events in Patients with Immune-Mediated Thrombosis. Blood. 106: 726-726. DOI: 10.1182/Blood.V106.11.726.726 |
0.317 |
|
| 2005 |
Giangrande PH, Zhang J, Layzer J, Hagen O, Nevins JR, Sullenger BA. 377. Developing siRNAs to the E2Fs to Control Vascular Growth and Remodeling Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.380 |
0.307 |
|
| 2004 |
Giangrande PH, Zhu W, Schlisio S, Sun X, Mori S, Gaubatz S, Nevins JR. A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription. Genes & Development. 18: 2941-51. PMID 15574595 DOI: 10.1101/Gad.1239304 |
0.449 |
|
| 2004 |
Zhu W, Giangrande PH, Nevins JR. E2Fs link the control of G1/S and G2/M transcription. The Embo Journal. 23: 4615-26. PMID 15510213 DOI: 10.1038/Sj.Emboj.7600459 |
0.41 |
|
| 2004 |
Seo D, Wang T, Dressman H, Herderick EE, Iversen ES, Dong C, Vata K, Milano CA, Rigat F, Pittman J, Nevins JR, West M, Goldschmidt-Clermont PJ. Gene expression phenotypes of atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1922-7. PMID 15297278 DOI: 10.1161/01.Atv.0000141358.65242.1F |
0.335 |
|
| 2004 |
Pittman J, Huang E, Dressman H, Horng CF, Cheng SH, Tsou MH, Chen CM, Bild A, Iversen ES, Huang AT, Nevins JR, West M. Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes. Proceedings of the National Academy of Sciences of the United States of America. 101: 8431-6. PMID 15152076 DOI: 10.1073/Pnas.0401736101 |
0.316 |
|
| 2004 |
Berchuck A, Iversen ES, Lancaster JM, Dressman HK, West M, Nevins JR, Marks JR. Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays. American Journal of Obstetrics and Gynecology. 190: 910-25. PMID 15118612 DOI: 10.1016/J.Ajog.2004.02.005 |
0.32 |
|
| 2004 |
Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G, Hahn WC, Stukenberg PT, Shenolikar S, Uchida T, Counter CM, Nevins JR, Means AR, Sears R. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nature Cell Biology. 6: 308-18. PMID 15048125 DOI: 10.1038/Ncb1110 |
0.311 |
|
| 2004 |
Giangrande PH, Zhu W, Rempel RE, Laakso N, Nevins JR. Combinatorial gene control involving E2F and E Box family members. The Embo Journal. 23: 1336-47. PMID 15014447 DOI: 10.1038/Sj.Emboj.7600134 |
0.456 |
|
| 2004 |
Lancaster JM, Dressman HK, Whitaker RS, Havrilesky L, Gray J, Marks JR, Nevins JR, Berchuck A. Gene expression patterns that characterize advanced stage serous ovarian cancers. Journal of the Society For Gynecologic Investigation. 11: 51-9. PMID 14706684 DOI: 10.1016/J.Jsgi.2003.07.004 |
0.305 |
|
| 2004 |
Cook JG, Chasse DA, Nevins JR. The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells. The Journal of Biological Chemistry. 279: 9625-33. PMID 14672932 DOI: 10.1074/Jbc.M311933200 |
0.423 |
|
| 2004 |
Smith C, Glozak M, Gasparetto M, Rempel R, Domens J, Cress D, Nevins J. E2F4 Plays a Critical Role in Early B-Cell Development. Blood. 104: 318-318. DOI: 10.1182/Blood.V104.11.318.318 |
0.347 |
|
| 2004 |
Tanner AK, Nevins J, Sullenger B. 202. Using RNA to Inhibit Intimal Hperplasia by Blocking E2F Function Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.112 |
0.363 |
|
| 2004 |
Dobra A, Hans C, Jones B, Nevins JR, Yao G, West M. Sparse graphical models for exploring gene expression data Journal of Multivariate Analysis. 90: 196-212. DOI: 10.1016/J.Jmva.2004.02.009 |
0.335 |
|
| 2003 |
Huang ES, Black EP, Dressman H, West M, Nevins JR. Gene expression phenotypes of oncogenic signaling pathways. Cell Cycle (Georgetown, Tex.). 2: 415-7. PMID 12963829 DOI: 10.4161/Cc.2.5.492 |
0.409 |
|
| 2003 |
Hallstrom TC, Nevins JR. Specificity in the activation and control of transcription factor E2F-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 10848-53. PMID 12954980 DOI: 10.1073/Pnas.1831408100 |
0.421 |
|
| 2003 |
Nevins JR, Huang ES, Dressman H, Pittman J, Huang AT, West M. Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction. Human Molecular Genetics. 12: R153-7. PMID 12928487 DOI: 10.1093/Hmg/Ddg287 |
0.331 |
|
| 2003 |
Huang E, West M, Nevins JR. Gene expression profiling for prediction of clinical characteristics of breast cancer. Recent Progress in Hormone Research. 58: 55-73. PMID 12795414 DOI: 10.1210/Rp.58.1.55 |
0.343 |
|
| 2003 |
Huang E, Ishida S, Pittman J, Dressman H, Bild A, Kloos M, D'Amico M, Pestell RG, West M, Nevins JR. Gene expression phenotypic models that predict the activity of oncogenic pathways. Nature Genetics. 34: 226-30. PMID 12754511 DOI: 10.1038/Ng1167 |
0.433 |
|
| 2003 |
Giangrande PH, Hallstrom TC, Tunyaplin C, Calame K, Nevins JR. Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor. Molecular and Cellular Biology. 23: 3707-20. PMID 12748276 DOI: 10.1128/Mcb.23.11.3707-3720.2003 |
0.468 |
|
| 2003 |
Huang E, Cheng SH, Dressman H, Pittman J, Tsou MH, Horng CF, Bild A, Iversen ES, Liao M, Chen CM, West M, Nevins JR, Huang AT. Gene expression predictors of breast cancer outcomes. Lancet (London, England). 361: 1590-6. PMID 12747878 DOI: 10.1016/S0140-6736(03)13308-9 |
0.317 |
|
| 2002 |
Schlisio S, Halperin T, Vidal M, Nevins JR. Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function. The Embo Journal. 21: 5775-86. PMID 12411495 DOI: 10.1093/Emboj/Cdf577 |
0.425 |
|
| 2002 |
Martell RE, Nevins JR, Sullenger BA. Optimizing aptamer activity for gene therapy applications using expression cassette SELEX. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 30-4. PMID 12095300 DOI: 10.1006/Mthe.2002.0624 |
0.368 |
|
| 2002 |
Cook JG, Park CH, Burke TW, Leone G, DeGregori J, Engel A, Nevins JR. Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. Proceedings of the National Academy of Sciences of the United States of America. 99: 1347-52. PMID 11805305 DOI: 10.1073/Pnas.032677499 |
0.616 |
|
| 2002 |
Sears RC, Nevins JR. Signaling networks that link cell proliferation and cell fate. The Journal of Biological Chemistry. 277: 11617-20. PMID 11805123 DOI: 10.1074/Jbc.R100063200 |
0.349 |
|
| 2002 |
Kegel KB, Meloni AR, Yi Y, Kim YJ, Doyle E, Cuiffo BG, Sapp E, Wang Y, Qin ZH, Chen JD, Nevins JR, Aronin N, DiFiglia M. Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription. The Journal of Biological Chemistry. 277: 7466-76. PMID 11739372 DOI: 10.1074/Jbc.M103946200 |
0.775 |
|
| 2001 |
Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 414: 457-62. PMID 11719808 DOI: 10.1038/35106593 |
0.455 |
|
| 2001 |
West M, Blanchette C, Dressman H, Huang E, Ishida S, Spang R, Zuzan H, Olson JA, Marks JR, Nevins JR. Predicting the clinical status of human breast cancer by using gene expression profiles. Proceedings of the National Academy of Sciences of the United States of America. 98: 11462-7. PMID 11562467 DOI: 10.1073/Pnas.201162998 |
0.331 |
|
| 2001 |
Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, ... ... Nevins JR, et al. Myc requires distinct E2F activities to induce S phase and apoptosis. Molecular Cell. 8: 105-13. PMID 11511364 DOI: 10.1016/S1097-2765(01)00275-1 |
0.411 |
|
| 2001 |
Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, Nevins JR. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Molecular and Cellular Biology. 21: 4684-99. PMID 11416145 DOI: 10.1128/Mcb.21.14.4684-4699.2001 |
0.444 |
|
| 2001 |
Burke TW, Cook JG, Asano M, Nevins JR. Replication Factors MCM2 and ORC1 Interact with the Histone Acetyltransferase HBO1 Journal of Biological Chemistry. 276: 15397-15408. PMID 11278932 DOI: 10.1074/Jbc.M011556200 |
0.366 |
|
| 2001 |
Nevins JR. The Rb/E2F pathway and cancer. Human Molecular Genetics. 10: 699-703. PMID 11257102 DOI: 10.1093/Hmg/10.7.699 |
0.394 |
|
| 2000 |
Gaubatz S, Lindeman GJ, Ishida S, Jakoi L, Nevins JR, Livingston DM, Rempel RE. E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control Molecular Cell. 6: 729-735. PMID 11030352 DOI: 10.1016/S1097-2765(00)00071-X |
0.394 |
|
| 2000 |
Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes & Development. 14: 2501-14. PMID 11018017 DOI: 10.1101/Gad.836800 |
0.349 |
|
| 2000 |
Rempel RE, Saenz-Robles MT, Storms R, Morham S, Ishida S, Engel A, Jakoi L, Melhem MF, Pipas JM, Smith C, Nevins JR. Loss of E2F4 activity leads to abnormal development of multiple cellular lineages Molecular Cell. 6: 293-306. PMID 10983977 DOI: 10.1016/S1097-2765(00)00030-7 |
0.323 |
|
| 2000 |
Adams MR, Sears R, Nuckolls F, Leone G, Nevins JR. Complex transcriptional regulatory mechanisms control expression of the E2F3 locus. Molecular and Cellular Biology. 20: 3633-9. PMID 10779353 DOI: 10.1128/Mcb.20.10.3633-3639.2000 |
0.457 |
|
| 2000 |
Leone G, Nuckolls F, Ishida S, Adams M, Sears R, Jakoi L, Miron A, Nevins JR. Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins. Molecular and Cellular Biology. 20: 3626-32. PMID 10779352 DOI: 10.1128/Mcb.20.10.3626-3632.2000 |
0.441 |
|
| 1999 |
Meloni AR, Smith EJ, Nevins JR. A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor. Proceedings of the National Academy of Sciences of the United States of America. 96: 9574-9. PMID 10449734 DOI: 10.1073/Pnas.96.17.9574 |
0.792 |
|
| 1999 |
Leone G, DeGregori J, Jakoi L, Cook JG, Nevins JR. Collaborative role of E2F transcriptional activity and G1 cyclin- dependent kinase activity in the induction of S phase Proceedings of the National Academy of Sciences of the United States of America. 96: 6626-6631. PMID 10359762 DOI: 10.1073/Pnas.96.12.6626 |
0.586 |
|
| 1999 |
Sears R, Leone G, DeGregori J, Nevins JR. Ras enhances Myc protein stability Molecular Cell. 3: 169-179. PMID 10078200 DOI: 10.1016/S1097-2765(00)80308-1 |
0.554 |
|
| 1998 |
Leone G, DeGregori J, Yan Z, Jakoi L, Ishida S, Williams RS, Nevins JR. E2F3 activity is regulated during the cell cycle and is required for the induction of S phase Genes and Development. 12: 2120-2130. PMID 9679057 DOI: 10.1101/Gad.12.14.2120 |
0.659 |
|
| 1998 |
Yan Z, Degregori J, Shohet R, Leone G, Stillman B, Nevins JR, Williams RS. Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 95: 3603-3608. PMID 9520412 DOI: 10.1073/Pnas.95.7.3603 |
0.64 |
|
| 1997 |
Nevins JR, Leone G, DeGregori J, Jakoi L. Role of the Rb/E2F pathway in cell growth control Journal of Cellular Physiology. 173: 233-236. PMID 9365528 DOI: 10.1002/(Sici)1097-4652(199711)173:2<233::Aid-Jcp27>3.0.Co;2-F |
0.56 |
|
| 1997 |
Sears R, Ohtani K, Nevins JR. Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals. Molecular and Cellular Biology. 17: 5227-35. PMID 9271400 DOI: 10.1128/Mcb.17.9.5227 |
0.45 |
|
| 1997 |
Nevins JR, Degregori J, Jakoi L, Leone G. Functional analysis of E2F transcription factor Methods in Enzymology. 283: 205-219. PMID 9251021 DOI: 10.1016/S0076-6879(97)83017-0 |
0.66 |
|
| 1997 |
Degregori J, Leone G, Miron A, Jakoi L, Nevins JR. Distinct roles for E2F proteins in cell growth control and apoptosis Proceedings of the National Academy of Sciences of the United States of America. 94: 7245-7250. PMID 9207076 DOI: 10.1073/Pnas.94.14.7245 |
0.639 |
|
| 1997 |
Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F Nature. 387: 422-426. PMID 9163430 DOI: 10.1038/387422A0 |
0.588 |
|
| 1997 |
Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR. Erratum: Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F Nature. 387: 932-932. DOI: 10.1038/43230 |
0.551 |
|
| 1996 |
Ishizaki J, Nevins JR, Sullenger BA. Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function. Nature Medicine. 2: 1386-1389. PMID 8946842 DOI: 10.1038/Nm1296-1386 |
0.408 |
|
| 1996 |
Ohtani K, DeGregori J, Leone G, Herendeen DR, Kelly TJ, Nevins JR. Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. Molecular and Cellular Biology. 16: 6977-84. PMID 8943353 DOI: 10.1128/Mcb.16.12.6977 |
0.661 |
|
| 1996 |
Smith EJ, Leone G, DeGregori J, Jakoi L, Nevins JR. The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state Molecular and Cellular Biology. 16: 6965-6976. PMID 8943352 DOI: 10.1128/Mcb.16.12.6965 |
0.618 |
|
| 1996 |
Asano M, Nevins JR, Wharton RP. Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes & Development. 10: 1422-32. PMID 8647438 DOI: 10.1101/Gad.10.11.1422 |
0.373 |
|
| 1996 |
Khleif SN, DeGregori J, Yee CL, Otterson GA, Kaye FJ, Nevins JR, Howley PM. Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proceedings of the National Academy of Sciences of the United States of America. 93: 4350-4. PMID 8633069 DOI: 10.1073/Pnas.93.9.4350 |
0.637 |
|
| 1996 |
Cress WD, Nevins JR. A role for a bent DNA structure in E2F-mediated transcription activation. Molecular and Cellular Biology. 16: 2119-27. PMID 8628278 DOI: 10.1128/Mcb.16.5.2119 |
0.348 |
|
| 1996 |
Ikeda MA, Jakoi L, Nevins JR. A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 93: 3215-20. PMID 8622916 DOI: 10.1073/Pnas.93.8.3215 |
0.43 |
|
| 1995 |
Ohtani K, Degregori J, Nevins JR. Regulation of the cyclin E gene by transcription factor E2F1 Proceedings of the National Academy of Sciences of the United States of America. 92: 12146-12150. PMID 8618861 DOI: 10.1073/Pnas.92.26.12146 |
0.659 |
|
| 1995 |
Yan DH, Weiss EA, Nevins JR. Identification of an activity in B-cell extracts that selectively impairs the formation of an immunoglobulin mu s poly(A) site processing complex. Molecular and Cellular Biology. 15: 1901-6. PMID 7891683 DOI: 10.1128/Mcb.15.4.1901 |
0.319 |
|
| 1995 |
Kowalik TF, DeGregori J, Schwarz JK, Nevins JR. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis Journal of Virology. 69: 2491-2500. PMID 7884898 DOI: 10.1128/Jvi.69.4.2491-2500.1995 |
0.62 |
|
| 1995 |
Schwarz JK, Bassing CH, Kovesdi I, Datto MB, Blazing M, George S, Wang XF, Nevins JR. Expression of the E2F1 transcription factor overcomes type β transforming growth factor-mediated growth suppression Proceedings of the National Academy of Sciences of the United States of America. 92: 483-487. PMID 7831315 DOI: 10.1073/Pnas.92.2.483 |
0.315 |
|
| 1995 |
Smith EJ, Nevins JR. The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2 Molecular and Cellular Biology. 15: 338-344. PMID 7799940 DOI: 10.1128/Mcb.15.1.338 |
0.407 |
|
| 1995 |
DeGregori J, Kowalik T, Nevins JR. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes Molecular and Cellular Biology. 15: 4215-4224. PMID 7623816 DOI: 10.1128/Mcb.15.8.4215 |
0.65 |
|
| 1995 |
DeGregori J, Leone G, Ohtani K, Miron A, Nevins JR. E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity Genes and Development. 9: 2783-2887. PMID 7498785 DOI: 10.1101/Gad.9.23.2873 |
0.574 |
|
| 1994 |
Cress WD, Nevins JR. Interacting domains of E2F1, DP1, and the adenovirus E4 protein. Journal of Virology. 68: 4213-9. PMID 8207796 DOI: 10.1128/Jvi.68.7.4213-4219.1994 |
0.375 |
|
| 1994 |
Nevins JR. Cell cycle targets of the DNA tumor viruses. Current Opinion in Genetics & Development. 4: 130-4. PMID 8193532 DOI: 10.1016/0959-437X(94)90101-5 |
0.379 |
|
| 1994 |
Ohtani K, Nevins JR. Functional properties of a Drosophila homolog of the E2F1 gene. Molecular and Cellular Biology. 14: 1603-12. PMID 8114698 DOI: 10.1128/Mcb.14.3.1603 |
0.436 |
|
| 1994 |
Kraus VB, Inostroza JA, Yeung K, Reinberg D, Nevins JR. Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A Proceedings of the National Academy of Sciences of the United States of America. 91: 6279-6282. PMID 8022773 DOI: 10.1073/Pnas.91.14.6279 |
0.411 |
|
| 1994 |
Johnson DG, Ohtani K, Nevins JR. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes & Development. 8: 1514-25. PMID 7958836 DOI: 10.1101/Gad.8.13.1514 |
0.413 |
|
| 1994 |
Johnson DG, Cress WD, Jakoi L, Nevins JR. Oncogenic capacity of the E2F1 gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 12823-7. PMID 7809128 DOI: 10.1073/Pnas.91.26.12823 |
0.438 |
|
| 1993 |
Schwarz JK, Devoto SH, Smith EJ, Chellappan SP, Jakoi L, Nevins JR. Interactions of the p107 and Rb proteins with E2F during the cell proliferation response. The Embo Journal. 12: 1013-20. PMID 8458319 DOI: 10.1002/J.1460-2075.1993.Tb05742.X |
0.743 |
|
| 1993 |
Ikeda MA, Nevins JR. Identification of distinct roles for separate E1A domains in disruption of E2F complexes. Molecular and Cellular Biology. 13: 7029-35. PMID 8413292 DOI: 10.1128/Mcb.13.11.7029 |
0.335 |
|
| 1993 |
Cress WD, Johnson DG, Nevins JR. A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4. Molecular and Cellular Biology. 13: 6314-25. PMID 8413230 DOI: 10.1128/Mcb.13.10.6314 |
0.433 |
|
| 1993 |
Johnson DG, Schwarz JK, Cress WD, Nevins JR. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature. 365: 349-52. PMID 8377827 DOI: 10.1038/365349A0 |
0.479 |
|
| 1993 |
Nevins JR. Transcriptional activation by the adenovirus E1A proteins Seminars in Virology. 4: 25-31. DOI: 10.1016/1044-5773(93)80005-9 |
0.452 |
|
| 1992 |
Nevins JR. Transcriptional activation by viral regulatory proteins. Trends in Biochemical Sciences. 16: 435-9. PMID 1663668 DOI: 10.1016/0968-0004(91)90171-Q |
0.388 |
|
| 1992 |
Nevins JR. Transcriptional regulation. A closer look at E2F. Nature. 358: 375-6. PMID 1641018 DOI: 10.1038/358375A0 |
0.365 |
|
| 1992 |
Hiebert SW, Chellappan SP, Horowitz JM, Nevins JR. The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F Genes and Development. 6: 177-185. PMID 1531329 DOI: 10.1101/Gad.6.2.177 |
0.439 |
|
| 1992 |
Nevins JR. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (New York, N.Y.). 258: 424-9. PMID 1411535 DOI: 10.1126/science.1411535 |
0.344 |
|
| 1992 |
Kraus VB, Moran E, Nevins JR. Promoter-Specific trans-Activation by the Adenovirus E1A12S Product Involves Separate E1A Domains Molecular and Cellular Biology. 12: 4391-4399. PMID 1406628 DOI: 10.1128/Mcb.12.10.4391 |
0.397 |
|
| 1992 |
Chellappan S, Kraus VB, Kroger B, Munger K, Howley PM, Phelps WC, Nevins JR. Adeno virus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product Proceedings of the National Academy of Sciences of the United States of America. 89: 4549-4553. PMID 1316611 DOI: 10.1073/Pnas.89.10.4549 |
0.409 |
|
| 1992 |
Devoto SH, Mudryj M, Pines J, Hunter T, Nevins JR. A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell. 68: 167-76. PMID 1310073 DOI: 10.1016/0092-8674(92)90215-X |
0.725 |
|
| 1991 |
Gilmartin GM, Nevins JR. Molecular analyses of two poly(A) site-processing factors that determine the recognition and efficiency of cleavage of the pre-mRNA. Molecular and Cellular Biology. 11: 2432-8. PMID 2017162 DOI: 10.1128/Mcb.11.5.2432 |
0.325 |
|
| 1991 |
Nevins JR. Utilization of cellular transcription factors for adenovirus-induced transcription. Virus Research. 20: 1-10. PMID 1927048 DOI: 10.1016/0168-1702(91)90056-2 |
0.36 |
|
| 1991 |
Nevins JR, Chellappan SP, Mudryj M, Hiebert S, Devoto S, Horowitz J, Hunter T, Pines J. E2F transcription factor is a target for the RB protein and the cyclin A protein Cold Spring Harbor Symposia On Quantitative Biology. 56: 157-162. PMID 1840249 DOI: 10.1101/Sqb.1991.056.01.020 |
0.717 |
|
| 1991 |
Phelps WC, Bagchi S, Barnes JA, Raychaudhuri P, Kraus V, Münger K, Howley PM, Nevins JR. Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism. Journal of Virology. 65: 6922-30. PMID 1834862 DOI: 10.1128/Jvi.65.12.6922-6930.1991 |
0.348 |
|
| 1991 |
Neill SD, Nevins JR. Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activity. Journal of Virology. 65: 5364-73. PMID 1832724 DOI: 10.1128/jvi.65.10.5364-5373.1991 |
0.305 |
|
| 1991 |
Raychaudhuri P, Bagchi S, Devoto SH, Kraus VB, Moran E, Nevins JR. Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes Genes and Development. 5: 1200-1211. PMID 1829698 DOI: 10.1101/Gad.5.7.1200 |
0.729 |
|
| 1991 |
Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR. Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A Cell. 65: 1243-1253. PMID 1829647 DOI: 10.1016/0092-8674(91)90019-U |
0.73 |
|
| 1991 |
Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR. The E2F transcription factor is a cellular target for the RB protein Cell. 65: 1053-1061. PMID 1828392 DOI: 10.1016/0092-8674(91)90557-F |
0.452 |
|
| 1991 |
Hiebert SW, Blake M, Azizkhan J, Nevins JR. Role of E2F transcription factor in E1A-mediated trans activation of cellular genes Journal of Virology. 65: 3547-3552. PMID 1828272 DOI: 10.1128/Jvi.65.7.3547-3552.1991 |
0.404 |
|
| 1991 |
Nicholas J, Nevins JR. Distinct DNA targets for trans-activation by HTLV-1 tax and adenovirus E1A. Virology. 182: 156-67. PMID 1827222 DOI: 10.1016/0042-6822(91)90659-Y |
0.349 |
|
| 1991 |
Weigel RJ, Devoto SH, Nevins JR. Adenovirus 12S E1A gene represses differentiation of F9 teratocarcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 9878-82. PMID 1702220 DOI: 10.1073/Pnas.87.24.9878 |
0.687 |
|
| 1991 |
Ahmed YF, Gilmartin GM, Hanly SM, Nevins JR, Greene WC. The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation. Cell. 64: 727-37. PMID 1671761 DOI: 10.1016/0092-8674(91)90502-P |
0.384 |
|
| 1991 |
Weiss EA, Gilmartin GM, Nevins JR. Poly(A) site efficiency reflects the stability of complex formation involving the downstream element. The Embo Journal. 10: 215-9. PMID 1671216 DOI: 10.1002/J.1460-2075.1991.Tb07938.X |
0.328 |
|
| 1990 |
Nevins JR. Mechanisms of viral-mediated trans-activation of transcription. Advances in Virus Research. 37: 35-83. PMID 2513709 DOI: 10.1016/S0065-3527(08)60832-5 |
0.386 |
|
| 1990 |
Rooney RJ, Raychaudhuri P, Nevins JR. E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: A role for E4F in E1A trans activation Molecular and Cellular Biology. 10: 5138-5149. PMID 2169022 DOI: 10.1128/Mcb.10.10.5138 |
0.366 |
|
| 1990 |
Bagchi S, Raychaudhuri P, Nevins JR. Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: A novel mechanism for E1A trans-activation Cell. 62: 659-669. PMID 2143697 DOI: 10.1016/0092-8674(90)90112-R |
0.443 |
|
| 1990 |
Chellappan SP, Nevins JR. DNA octamer element can confer E1A trans-activation, and adenovirus infection results in a stimulation of the DNA-binding activity of OTF-1/NFIII factor Proceedings of the National Academy of Sciences of the United States of America. 87: 5878-5882. PMID 2143023 DOI: 10.1073/Pnas.87.15.5878 |
0.387 |
|
| 1990 |
Mudryj M, Hiebert SW, Nevins JR. A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway Embo Journal. 9: 2179-2184. PMID 2141565 DOI: 10.1002/J.1460-2075.1990.Tb07387.X |
0.46 |
|
| 1990 |
Raychaudhuri P, Bagchi S, Neill SD, Nevins JR. Activation of the E2F transcription factor in adenovirus-infected cells involves E1A-dependent stimulation of DNA-binding activity and induction of cooperative binding mediated by an E4 gene product Journal of Virology. 64: 2702-2710. PMID 2139893 DOI: 10.1128/Jvi.64.6.2702-2710.1990 |
0.394 |
|
| 1990 |
Neill SD, Hemstrom C, Virtanen A, Nevins JR. An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F. Proceedings of the National Academy of Sciences of the United States of America. 87: 2008-12. PMID 2137929 DOI: 10.1073/Pnas.87.5.2008 |
0.364 |
|
| 1990 |
Simon MC, Rooney RJ, Fisch TM, Heintz N, Nevins JR. E1A-dependent trans-activation of the c-fos promoter requires the TATAA sequence. Proceedings of the National Academy of Sciences of the United States of America. 87: 513-7. PMID 2137244 DOI: 10.1073/Pnas.87.2.513 |
0.358 |
|
| 1989 |
Raychaudhuri P, Bagchi S, Nevins JR. DNA-binding activity of the adenovirus-induced E4F transcription factor is regulated by phosphorylation Genes &Amp; Development. 3: 620-627. PMID 2545525 DOI: 10.1101/Gad.3.5.620 |
0.404 |
|
| 1989 |
Reichel R, Neill SD, Kovesdi I, Simon MC, Raychaudhuri P, Nevins JR. The adenovirus E4 gene, in addition to the E1A gene, is important for trans-activation of E2 transcription and for E2F activation. Journal of Virology. 63: 3643-50. PMID 2527310 DOI: 10.1128/Jvi.63.9.3643-3650.1989 |
0.4 |
|
| 1989 |
Bagchi S, Raychaudhuri P, Nevins JR. Phosphorylation-dependent activation of the adenovirus-inducible E2F transcription factor in a cell-free system Proceedings of the National Academy of Sciences of the United States of America. 86: 4352-4356. PMID 2525256 DOI: 10.1073/Pnas.86.12.4352 |
0.375 |
|
| 1989 |
Hiebert SW, Lipp M, Nevins JR. E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor Proceedings of the National Academy of Sciences of the United States of America. 86: 3594-3598. PMID 2524830 DOI: 10.1073/Pnas.86.10.3594 |
0.417 |
|
| 1988 |
Nevins JR, Raychaudhuri P, Yee AS, Rooney RJ, Kovesdi I, Reichel R. Transactivation by the adenovirus E1A gene. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 66: 578-83. PMID 3048331 DOI: 10.1139/O88-068 |
0.449 |
|
| 1988 |
Lazaridis I, Babich A, Nevins JR. Role of the adenovirus 72-kDa DNA binding protein in the rapid decay of early viral mRNA Virology. 165: 438-445. PMID 2970153 DOI: 10.1016/0042-6822(88)90587-9 |
0.346 |
|
| 1988 |
Reichel R, Kovesdi I, Nevins JR. Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control. Proceedings of the National Academy of Sciences of the United States of America. 85: 387-90. PMID 2963331 DOI: 10.1073/Pnas.85.2.387 |
0.399 |
|
| 1988 |
Simon MC, Fisch TM, Benecke BJ, Nevins JR, Heintz N. Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation. Cell. 52: 723-9. PMID 2830991 DOI: 10.1016/0092-8674(88)90410-2 |
0.344 |
|
| 1988 |
Adami G, Nevins JR. Splice site selection dominates over poly(A) site choice in RNA production from complex adenovirus transcription units. The Embo Journal. 7: 2107-2116. DOI: 10.1002/J.1460-2075.1988.Tb03050.X |
0.305 |
|
| 1987 |
Kovesdi I, Satake M, Furukawa K, Reichel R, Ito Y, Nevins JR. A factor discriminating between the wild-type and a mutant polyomavirus enhancer. Nature. 328: 87-9. PMID 3037380 DOI: 10.1038/328087A0 |
0.369 |
|
| 1987 |
Simon MC, Kitchener K, Kao HT, Hickey E, Weber L, Voellmy R, Heintz N, Nevins JR. Selective induction of human heat shock gene transcription by the adenovirus E1A gene products, including the 12S E1A product. Molecular and Cellular Biology. 7: 2884-90. PMID 2959854 DOI: 10.1128/Mcb.7.8.2884 |
0.381 |
|
| 1987 |
Kovesdi I, Reichel R, Nevins JR. Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control. Proceedings of the National Academy of Sciences of the United States of America. 84: 2180-4. PMID 2951737 DOI: 10.1073/Pnas.84.8.2180 |
0.387 |
|
| 1987 |
Reichel R, Kovesdi I, Nevins JR. Developmental control of a promoter-specific factor that is also regulated by the E1A gene product. Cell. 48: 501-6. PMID 2948654 DOI: 10.1016/0092-8674(87)90200-5 |
0.358 |
|
| 1987 |
Yee AS, Reichel R, Kovesdi I, Nevins JR. Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex. The Embo Journal. 6: 2061-2068. DOI: 10.1002/J.1460-2075.1987.Tb02471.X |
0.363 |
|
| 1986 |
Kao HT, Nevins JR. Alteration of cellular gene expression in adenovirus transformed cells by post-transcriptional mechanisms. Nucleic Acids Research. 14: 7253-63. PMID 3763404 DOI: 10.1093/Nar/14.18.7253 |
0.36 |
|
| 1986 |
Nevins JR. Control of cellular and viral transcription during adenovirus infection. Crc Critical Reviews in Biochemistry. 19: 307-22. PMID 3009089 DOI: 10.3109/10409238609082543 |
0.331 |
|
| 1986 |
Kovesdi I, Reichel R, Nevins JR. Identification of a cellular transcription factor involved in E1A trans-activation. Cell. 45: 219-28. PMID 2938741 DOI: 10.1016/0092-8674(86)90386-7 |
0.411 |
|
| 1986 |
Kovesdi I, Reichel R, Nevins JR. E1A transcription induction: enhanced binding of a factor to upstream promoter sequences. Science (New York, N.Y.). 231: 719-22. PMID 2935935 DOI: 10.1126/science.2935935 |
0.317 |
|
| 1982 |
Nevins JR. Adenovirus gene expression: control at multiple steps of mRNA biogenesis. Cell. 28: 1-2. PMID 7066982 DOI: 10.1016/0092-8674(82)90366-X |
0.312 |
|
| 1980 |
Nevins JR, Winkler JJ. Regulation of early adenovirus transcription: a protein product of early region 2 specifically represses region 4 transcription. Proceedings of the National Academy of Sciences of the United States of America. 77: 1893-7. PMID 6929526 DOI: 10.1073/Pnas.77.4.1893 |
0.368 |
|
| 1980 |
Nevins JR. Definition and mapping of adenovirus 2 nuclear transcription. Methods in Enzymology. 65: 768-85. PMID 6246373 DOI: 10.1016/S0076-6879(80)65072-1 |
0.398 |
|
| 1979 |
Nevins JR, Ginsberg HS, Blanchard JM, Wilson MC, Darnell JE. Regulation of the primary expression of the early adenovirus transcription units. Journal of Virology. 32: 727-33. PMID 513202 DOI: 10.1128/Jvi.32.3.727-733.1979 |
0.328 |
|
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