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Hongwu Zheng, Ph.D. - Publications

Affiliations: 
2003 Boston University, Boston, MA, United States 
Area:
Molecular Biology
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Li F, Wang Y, Hwang I, Jang JY, Xu L, Deng Z, Yu EY, Cai Y, Wu C, Han Z, Huang YH, Huang X, Zhang L, Yao J, Lue NF, ... ... Zheng H, et al. Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance. Nature Communications. 14: 1756. PMID 36991019 DOI: 10.1038/s41467-023-37480-2  0.488
2023 Li F, Wang Y, Hwang I, Jang JY, Xu L, Deng Z, Yu EY, Cai Y, Wu C, Han Z, Huang YH, Huang X, Zhang L, Yao J, Lue NF, ... ... Zheng H, et al. Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance. Biorxiv : the Preprint Server For Biology. PMID 36798426 DOI: 10.1101/2023.02.10.528023  0.489
2021 Oh H, Hwang I, Jang JY, Wu L, Cao D, Yao J, Ying H, Li JY, Yao Y, Hu B, Wang Q, Zheng H, Paik J. Therapy-induced transdifferentiation promotes glioma growth independent of EGFR signaling. Cancer Research. PMID 33509942 DOI: 10.1158/0008-5472.CAN-20-1810  0.49
2020 Liang H, Wang Q, Wang D, Zheng H, Kalvakolanu DV, Lu H, Wen N, Chen X, Xu L, Ren J, Guo B, Zhang L. RGFP966, a Histone deacetylase 3 inhibitor, promotes glioma stem cell differentiation by blocking TGF-β signaling via SMAD7. Biochemical Pharmacology. 114118. PMID 32585142 DOI: 10.1016/J.Bcp.2020.114118  0.369
2020 Hwang I, Pan H, Yao J, Elemento O, Zheng H, Paik J. CIC is a critical regulator of neuronal differentiation. Jci Insight. PMID 32229723 DOI: 10.1172/Jci.Insight.135826  0.345
2019 Tu B, Yao J, Ferri-Borgogno S, Zhao J, Chen S, Wang Q, Yan L, Zhou X, Zhu C, Bang S, Chang Q, Bristow CA, Kang Y, Zheng H, Wang H, et al. YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma. Jci Insight. PMID 31557131 DOI: 10.1172/Jci.Insight.130811  0.574
2019 Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, Wang D, Chen X, Zhang S, Li Y, Zhang L. Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway. International Journal of Oncology. PMID 31485609 DOI: 10.3892/Ijo.2019.4863  0.393
2019 Li F, Deng Z, Zhang L, Wu C, Jin Y, Hwang I, Vladimirova O, Xu L, Yang L, Lu B, Dheekollu J, Li JY, Feng H, Hu J, Vakoc CR, ... ... Zheng H, et al. ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization. The Embo Journal. e96659. PMID 31454099 DOI: 10.15252/Embj.201796659  0.548
2019 Xu G, Zheng H, Li JY. Next-generation whole exome sequencing of glioblastoma with a primitive neuronal component. Brain Tumor Pathology. PMID 30715630 DOI: 10.1007/S10014-019-00334-1  0.319
2018 Hwang I, Cao D, Na Y, Kim DY, Zhang T, Yao J, Oh H, Hu J, Zheng H, Yao Y, Paik J. Far Upstream Element-Binding Protein 1 Regulates LSD1 Alternative Splicing to Promote Terminal Differentiation of Neural Progenitors. Stem Cell Reports. PMID 29606613 DOI: 10.1016/J.Stemcr.2018.02.013  0.35
2017 Calvert AE, Chalastanis A, Wu Y, Hurley LA, Kouri FM, Bi Y, Kachman M, May JL, Bartom E, Hua Y, Mishra RK, Schiltz GE, Dubrovskyi O, Mazar AP, Peter ME, ... Zheng H, et al. Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation. Cell Reports. 19: 1858-1873. PMID 28564604 DOI: 10.1016/J.Celrep.2017.05.014  0.375
2017 Singh DK, Kollipara RK, Vemireddy V, Yang XL, Sun Y, Regmi N, Klingler S, Hatanpaa KJ, Raisanen J, Cho SK, Sirasanagandla S, Nannepaga S, Piccirillo S, Mashimo T, Wang S, ... ... Zheng H, et al. Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. Cell Reports. 18: 961-976. PMID 28122245 DOI: 10.1016/J.Celrep.2016.12.064  0.423
2015 Klingler S, Guo B, Yao J, Yan H, Zhang L, Vaseva AV, Chen S, Canoll P, Horner JW, Wang YA, Paik JH, Ying H, Zheng H. Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms. Cancer Research. 75: 2109-19. PMID 25808866 DOI: 10.1158/0008-5472.Can-14-3122  0.531
2013 Hu J, Ho AL, Yuan L, Hu B, Hua S, Hwang SS, Zhang J, Hu T, Zheng H, Gan B, Wu G, Wang YA, Chin L, DePinho RA. From the Cover: Neutralization of terminal differentiation in gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 14520-7. PMID 23918370 DOI: 10.1073/Pnas.1308610110  0.421
2013 Zhang Y, Shin SJ, Liu D, Ivanova E, Foerster F, Ying H, Zheng H, Xiao Y, Chen Z, Protopopov A, Depinho RA, Paik JH. ZNF365 promotes stability of fragile sites and telomeres. Cancer Discovery. 3: 798-811. PMID 23776040 DOI: 10.1158/2159-8290.Cd-12-0536  0.584
2012 Genovese G, Ergun A, Shukla SA, Campos B, Hanna J, Ghosh P, Quayle SN, Rai K, Colla S, Ying H, Wu CJ, Sarkar S, Xiao Y, Zhang J, Zhang H, ... ... Zheng H, et al. microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma. Cancer Discovery. 2: 736-49. PMID 22750848 DOI: 10.1158/2159-8290.Cd-12-0111  0.507
2012 Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell. 149: 656-70. PMID 22541435 DOI: 10.1016/J.Cell.2012.01.058  0.558
2012 Ying H, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik J, Lim C, Guimaraes AR, Kimmelman AC, Martin ES, Chang J, Hezel A, et al. Abstract A101: Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A101  0.56
2011 Ying H, Elpek KG, Vinjamoori A, Zimmerman SM, Chu GC, Yan H, Fletcher-Sananikone E, Zhang H, Liu Y, Wang W, Ren X, Zheng H, Kimmelman AC, Paik JH, Lim C, et al. PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network. Cancer Discovery. 1: 158-69. PMID 21984975 DOI: 10.1158/2159-8290.Cd-11-0031  0.577
2010 Zheng H, Ying H, Wiedemeyer R, Yan H, Quayle SN, Ivanova EV, Paik JH, Zhang H, Xiao Y, Perry SR, Hu J, Vinjamoori A, Gan B, Sahin E, Chheda MG, et al. PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas. Cancer Cell. 17: 497-509. PMID 20478531 DOI: 10.1016/J.Ccr.2010.03.020  0.55
2010 Ying H, Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J, Dhakal S, Ivanova E, Xiao Y, Zhang H, Hu J, Stommel JM, Lee MA, Chen AJ, et al. Mig-6 controls EGFR trafficking and suppresses gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6912-7. PMID 20351267 DOI: 10.1073/Pnas.0914930107  0.556
2009 Paik JH, Ding Z, Narurkar R, Ramkissoon S, Muller F, Kamoun WS, Chae SS, Zheng H, Ying H, Mahoney J, Hiller D, Jiang S, Protopopov A, Wong WH, Chin L, et al. FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell. 5: 540-53. PMID 19896444 DOI: 10.1016/J.Stem.2009.09.013  0.545
2008 Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, et al. Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harbor Symposia On Quantitative Biology. 73: 427-37. PMID 19150964 DOI: 10.1101/Sqb.2008.73.047  0.612
2008 Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, et al. Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 19372-7. PMID 19050074 DOI: 10.1073/Pnas.0809966105  0.556
2008 Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, et al. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature. 455: 1129-33. PMID 18948956 DOI: 10.1038/Nature07443  0.598
2008 Wiedemeyer R, Brennan C, Heffernan TP, Xiao Y, Mahoney J, Protopopov A, Zheng H, Bignell G, Furnari F, Cavenee WK, Hahn WC, Ichimura K, Collins VP, Chu GC, Stratton MR, et al. Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development. Cancer Cell. 13: 355-64. PMID 18394558 DOI: 10.1016/J.Ccr.2008.02.010  0.417
2005 Sdek P, Ying H, Chang DL, Qiu W, Zheng H, Touitou R, Allday MJ, Xiao ZX. MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein. Molecular Cell. 20: 699-708. PMID 16337594 DOI: 10.1016/J.Molcel.2005.10.017  0.731
2005 Ying H, Chang DL, Zheng H, McKeon F, Xiao ZX. DNA-binding and transactivation activities are essential for TAp63 protein degradation. Molecular and Cellular Biology. 25: 6154-64. PMID 15988026 DOI: 10.1128/Mcb.25.14.6154-6164.2005  0.72
2004 Sdek P, Ying H, Zheng H, Margulis A, Tang X, Tian K, Xiao ZX. The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth. The Journal of Biological Chemistry. 279: 53317-22. PMID 15485814 DOI: 10.1074/Jbc.M406062200  0.621
2003 Gu L, Ying H, Zheng H, Murray SA, Xiao ZX. The MDM2 RING finger is required for cell cycle-dependent regulation of its protein expression. Febs Letters. 544: 218-22. PMID 12782320 DOI: 10.1016/S0014-5793(03)00502-7  0.662
2003 Murray SA, Zheng H, Gu L, Jim Xiao ZX. IGF-1 activates p21 to inhibit UV-induced cell death. Oncogene. 22: 1703-11. PMID 12642873 DOI: 10.1038/Sj.Onc.1206327  0.551
2003 Gu L, Zheng H, Murray SA, Ying H, Jim Xiao ZX. Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis. Biochemical and Biophysical Research Communications. 302: 384-91. PMID 12604359 DOI: 10.1016/S0006-291X(03)00189-X  0.617
2002 Zheng H, You H, Zhou XZ, Murray SA, Uchida T, Wulf G, Gu L, Tang X, Lu KP, Xiao ZX. The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature. 419: 849-53. PMID 12397361 DOI: 10.1038/Nature01116  0.569
2002 You H, Zheng H, Murray SA, Yu Q, Uchida T, Fan D, Xiao ZX. IGF-1 induces Pin1 expression in promoting cell cycle S-phase entry. Journal of Cellular Biochemistry. 84: 211-6. PMID 11787050 DOI: 10.1002/Jcb.10037  0.367
2002 Zheng H, You H, Zhou XZ, Murray SA, Uchida T, Wult G, Gu L, Tang X, Lu KP, Xiao ZJ. Erratum: The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response Nature. 420: 445-445. DOI: 10.1038/Nature01220  0.673
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