| Year |
Citation |
Score |
| 2023 |
Datta J, Kutay H, Nasser MW, Nuovo GJ, Wang B, Majumder S, Liu CG, Volinia S, Croce CM, Schmittgen TD, Ghoshal K, Jacob ST. Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis. Cancer Research. 83: 4181. PMID 38098455 DOI: 10.1158/0008-5472.CAN-23-2365 |
0.304 |
|
| 2023 |
Datta J, Majumder S, Bai S, Ghoshal K, Kutay H, Smith DS, Crabb JW, Jacob ST. Retraction: Physical and Functional Interaction of DNA Methyltransferase 3A with Mbd3 and Brg1 in Mouse Lymphosarcoma Cells. Cancer Research. 83: 4182. PMID 38098452 DOI: 10.1158/0008-5472.CAN-23-2344 |
0.648 |
|
| 2020 |
Teng KY, Barajas JM, Hu P, Jacob ST, Ghoshal K. Role of B Cell Lymphoma 2 in the Regulation of Liver Fibrosis in miR-122 Knockout Mice. Biology. 9. PMID 32650615 DOI: 10.3390/Biology9070157 |
0.416 |
|
| 2019 |
Lin CH, Elkholy KH, Wani NA, Li D, Hu P, Barajas JM, Yu L, Zhang X, Jacob ST, Khan WN, Bai XF, Noonan AM, Ghoshal K. Ibrutinib potentiates anti-hepatocarcinogenic efficacy of sorafenib by targeting EGFR in tumor cells and BTK in immune cells in the stroma. Molecular Cancer Therapeutics. PMID 31582534 DOI: 10.1158/1535-7163.Mct-19-0135 |
0.376 |
|
| 2018 |
Majumder S, Ghoshal K, Datta J, Bai S, Dong X, Quan N, Plass C, Jacob ST. Role of DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. The Journal of Biological Chemistry. 293: 12948. PMID 30120152 DOI: 10.1074/Jbc.W118.004970 |
0.783 |
|
| 2018 |
Dong X, Ghoshal K, Majumder S, Yadav SP, Jacob ST. Mitochondrial transcription factor A and its downstream targets are up-regulated in a rat hepatoma. The Journal of Biological Chemistry. 293: 12947. PMID 30120151 DOI: 10.1074/Jbc.W118.004969 |
0.68 |
|
| 2018 |
Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T, Majumder S, Wang B, Suster S, Jacob ST, Ghoshal K. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. The Journal of Biological Chemistry. 293: 12945. PMID 30120149 DOI: 10.1074/Jbc.W118.004967 |
0.336 |
|
| 2018 |
Barajas JM, Reyes R, Guerrero MJ, Jacob ST, Motiwala T, Ghoshal K. The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer. Scientific Reports. 8: 9105. PMID 29904144 DOI: 10.1038/S41598-018-27358-5 |
0.419 |
|
| 2018 |
Badawi M, Kim J, Dauki A, Sutaria D, Motiwala T, Reyes R, Wani N, Kolli S, Jiang J, Coss CC, Jacob ST, Phelps MA, Schmittgen TD. CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128. Oncotarget. 9: 26032-26045. PMID 29899840 DOI: 10.18632/Oncotarget.25430 |
0.312 |
|
| 2018 |
Ghoshal K, Datta J, Majumder S, Bai S, Kutay H, Motiwala T, Jacob ST. Correction for Ghoshal et al., "5-Aza-Deoxycytidine Induces Selective Degradation of DNA Methyltransferase 1 by a Proteasomal Pathway That Requires the KEN Box, Bromo-Adjacent Homology Domain, and Nuclear Localization Signal". Molecular and Cellular Biology. 38. PMID 29712769 DOI: 10.1128/Mcb.00539-17 |
0.66 |
|
| 2018 |
Bai S, Ghoshal K, Jacob ST. Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells. The Journal of Biological Chemistry. 293: 3592. PMID 29523698 DOI: 10.1074/jbc.W118.002434 |
0.665 |
|
| 2018 |
Majumder S, Ghoshal K, Datta J, Smith DS, Bai S, Jacob ST. Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. The Journal of Biological Chemistry. 293: 3591. PMID 29523697 DOI: 10.1074/jbc.W118.002433 |
0.677 |
|
| 2018 |
Bai S, Datta J, Jacob ST, Ghoshal K. Treatment of PC12 cells with nerve growth factor induces proteasomal degradation of T-cadherin that requires tyrosine phosphorylation of its cadherin domain. The Journal of Biological Chemistry. 293: 3590. PMID 29523696 DOI: 10.1074/jbc.W118.002432 |
0.64 |
|
| 2017 |
Wani N, Zhang B, Teng KY, Barajas J, Motiwala T, Hu P, Yu L, Brüschweiler R, Ghoshal K, Jacob ST. Reprograming of Glucose Metabolism by Zerumbone Suppresses Hepatocarcinogenesis. Molecular Cancer Research : McR. PMID 29187559 DOI: 10.1158/1541-7786.Mcr-17-0304 |
0.369 |
|
| 2017 |
Huang W, Mehta D, Sif S, Kent LN, Jacob ST, Ghoshal K, Mehta KD. Dietary fat/cholesterol-sensitive PKCβ-RB signaling: Potential role in NASH/HCC axis. Oncotarget. 8: 73757-73765. PMID 29088742 DOI: 10.18632/Oncotarget.17890 |
0.372 |
|
| 2017 |
Regan K, Reyes R, Jacob S, Payne P, Motiwala T. Abstract 1562: Drug repurposing for hepatocellular carcinoma enabled via transcriptomics data from experimental models of sorafenib resistance Cancer Research. 77: 1562-1562. DOI: 10.1158/1538-7445.Am2017-1562 |
0.311 |
|
| 2016 |
Teng KY, Han J, Zhang X, Hsu SH, He S, Wani N, Barajas J, Snyder LA, Frankel WL, Caligiuri MA, Jacob ST, Yu J, Ghoshal K. Blocking the Ccl2-Ccr2 axis using Ccl2 neutralizing antibody is an effective therapy for hepatocellular cancer in a mouse model. Molecular Cancer Therapeutics. PMID 27980102 DOI: 10.1158/1535-7163.Mct-16-0124 |
0.713 |
|
| 2015 |
Alinari L, Mahasenan KV, Yan F, Karkhanis V, Chung JH, Smith EM, Quinion C, Smith PL, Kim L, Patton JT, Lapalombella R, Yu B, Wu Y, Roy S, De Leo A, ... ... Jacob S, et al. Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation. Blood. 125: 2530-43. PMID 25742700 DOI: 10.1182/Blood-2014-12-619783 |
0.394 |
|
| 2015 |
Motiwala T, Kutay H, Zanesi N, Frissora FW, Mo X, Muthusamy N, Jacob ST. PTPROt-mediated regulation of p53/Foxm1 suppresses leukemic phenotype in a CLL mouse model. Leukemia. 29: 1350-9. PMID 25482129 DOI: 10.1038/Leu.2014.341 |
0.379 |
|
| 2015 |
Wang X, He H, Lu Y, Ren W, Teng KY, Chiang CL, Yang Z, Yu B, Hsu S, Jacob ST, Ghoshal K, Lee LJ. Indole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells via suppression of microRNA-21 and upregulation of phosphatase and tensin homolog. Biochimica Et Biophysica Acta. 1853: 244-53. PMID 25447674 DOI: 10.1016/J.Bbamcr.2014.10.017 |
0.714 |
|
| 2014 |
Yan F, Alinari L, Lustberg ME, Martin LK, Cordero-Nieves HM, Banasavadi-Siddegowda Y, Virk S, Barnholtz-Sloan J, Bell EH, Wojton J, Jacob NK, Chakravarti A, Nowicki MO, Wu X, Lapalombella R, ... ... Jacob S, et al. Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma. Cancer Research. 74: 1752-65. PMID 24453002 DOI: 10.1158/0008-5472.Can-13-0884 |
0.397 |
|
| 2014 |
Wang B, Hsu SH, Wang X, Kutay H, Bid HK, Yu J, Ganju RK, Jacob ST, Yuneva M, Ghoshal K. Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2. Hepatology (Baltimore, Md.). 59: 555-66. PMID 24038073 DOI: 10.1002/Hep.26712 |
0.738 |
|
| 2014 |
Motiwala T, Mustafa M, Kutay H, Sullivan RC, Teng K, Chowdhary V, Yu L, Ghoshal K, Jacob ST. Abstract 4359: Elucidation of the role of microRNA-155 in a murine model of non-alcoholic steatohepatitis Cancer Research. 74: 4359-4359. DOI: 10.1158/1538-7445.Am2014-4359 |
0.411 |
|
| 2013 |
Wang X, Yu B, Ren W, Mo X, Zhou C, He H, Jia H, Wang L, Jacob ST, Lee RJ, Ghoshal K, Lee LJ. Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 690-8. PMID 24121065 DOI: 10.1016/J.Jconrel.2013.09.027 |
0.335 |
|
| 2013 |
Hsu SH, Yu B, Wang X, Lu Y, Schmidt CR, Lee RJ, Lee LJ, Jacob ST, Ghoshal K. Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 1169-80. PMID 23727126 DOI: 10.1016/J.Nano.2013.05.007 |
0.722 |
|
| 2013 |
Hsu SH, Motiwala T, Roy S, Claus R, Mustafa M, Plass C, Freitas MA, Ghoshal K, Jacob ST. Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate. Journal of Cellular Biochemistry. 114: 1810-8. PMID 23533167 DOI: 10.1002/Jcb.24525 |
0.728 |
|
| 2013 |
Mims A, Walker AR, Huang X, Sun J, Wang H, Santhanam R, Dorrance AM, Walker C, Hoellerbauer P, Tarighat SS, Chan KK, Klisovic RB, Perrotti D, Caligiuri MA, Byrd JC, ... ... Jacob S, et al. Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia. Leukemia. 27: 871-8. PMID 23178755 DOI: 10.1038/Leu.2012.342 |
0.368 |
|
| 2012 |
Kutay H, Klepper C, Wang B, Hsu SH, Datta J, Yu L, Zhang X, Majumder S, Motiwala T, Khan N, Belury M, McClain C, Jacob S, Ghoshal K. Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet. Plos One. 7: e41949. PMID 22905112 DOI: 10.1371/Journal.Pone.0041949 |
0.703 |
|
| 2012 |
Datta J, Ghoshal K, Motiwala T, Jacob ST. Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1. Genes & Cancer. 3: 71-81. PMID 22893792 DOI: 10.1177/1947601912452665 |
0.354 |
|
| 2012 |
Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, ... Jacob ST, et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. The Journal of Clinical Investigation. 122: 2871-83. PMID 22820288 DOI: 10.1172/Jci63539 |
0.783 |
|
| 2012 |
Yan P, Frankhouser D, Murphy M, Tam HH, Rodriguez B, Curfman J, Trimarchi M, Geyer S, Wu YZ, Whitman SP, Metzeler K, Walker A, Klisovic R, Jacob S, Grever MR, et al. Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia. Blood. 120: 2466-74. PMID 22786882 DOI: 10.1182/Blood-2012-05-429175 |
0.342 |
|
| 2012 |
Yu B, Hsu SH, Zhou C, Wang X, Terp MC, Wu Y, Teng L, Mao Y, Wang F, Xue W, Jacob ST, Ghoshal K, Lee RJ, Lee LJ. Lipid nanoparticles for hepatic delivery of small interfering RNA. Biomaterials. 33: 5924-34. PMID 22652024 DOI: 10.1016/J.Biomaterials.2012.05.002 |
0.672 |
|
| 2012 |
Blum W, Schwind S, Tarighat SS, Geyer S, Eisfeld AK, Whitman S, Walker A, Klisovic R, Byrd JC, Santhanam R, Wang H, Curfman JP, Devine SM, Jacob S, Garr C, et al. Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia. Blood. 119: 6025-31. PMID 22566605 DOI: 10.1182/Blood-2012-03-413898 |
0.349 |
|
| 2012 |
Wang B, Hsu SH, Frankel W, Ghoshal K, Jacob ST. Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. Hepatology (Baltimore, Md.). 56: 186-97. PMID 22318941 DOI: 10.1002/Hep.25632 |
0.727 |
|
| 2012 |
Alinari L, Yan F, Smith P, Patton JT, Quinion C, Yu B, Earl CT, Lustberg ME, Villagomez L, Hertlein EK, Byrd JC, Ayers L, Motiwala T, Majumder S, Li C, ... ... Jacob ST, et al. Protein Arginine Methyltransferase 5 (PRMT5) Over-Expression Is Essential for Epstein-Barr Virus-Driven B-Cell Transformation. Blood. 120: 2378-2378. DOI: 10.1182/Blood.V120.21.2378.2378 |
0.374 |
|
| 2012 |
Motiwala T, Roy S, Liu S, Schwind S, Claus R, Mo X, Garzon R, Dohner H, Dohner K, Jarjoura D, Plass C, Marcucci G, Jacob ST. Aberrant Epigenetic Suppression of the Ptprot Gene Encoding a Protein Tyrosine Phosphatase Targeting KIT in Acute Myeloid Leukemia Blood. 120: 1322-1322. DOI: 10.1182/Blood.V120.21.1322.1322 |
0.364 |
|
| 2012 |
Schwind S, Blum W, Liu S, Tarighat SS, Geyer S, Klisovic R, Eisfeld A, Walker A, Whitman S, Ramasamy S, Wu Y, Jacob S, Caligiuri M, Grever M, Perrotti D, et al. Abstract CT-06: The combination of bortezomib (BOR) and decitabine (DEC): A phase I trial in patients (pts) with acute myeloid leukemia (AML) targeting FLT3 expression Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Ct-06 |
0.375 |
|
| 2012 |
Wang B, Hsu S, Frankel W, Ghoshal K, Jacob ST. Abstract 5155: Suppression of gluconeogenesis in hepatocellular carcinoma by miR-23 directed downregulation of key gluconeogenic enzymes and the transcription factorPGC-1α Cancer Research. 72: 5155-5155. DOI: 10.1158/1538-7445.Am2012-5155 |
0.728 |
|
| 2012 |
Motiwala T, Zanesi N, Roy S, Mustafa M, Kutay H, You J, Frissora F, Lu Y, Muthusamy N, Freitas M, Croce CM, Jacob ST. Abstract 1351: Analysis of the in vivo tumor suppressive potential of PTPROt (truncated protein tyrosine phosphatase receptor-type O) in CLL using a transgenic mouse model Cancer Research. 72: 1351-1351. DOI: 10.1158/1538-7445.Am2012-1351 |
0.354 |
|
| 2011 |
Lu Y, Roy S, Nuovo G, Ramaswamy B, Miller T, Shapiro C, Jacob ST, Majumder S. Anti-microRNA-222 (anti-miR-222) and -181B suppress growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal. The Journal of Biological Chemistry. 286: 42292-302. PMID 22009755 DOI: 10.1074/Jbc.M111.270926 |
0.385 |
|
| 2011 |
Motiwala T, Zanesi N, Datta J, Roy S, Kutay H, Checovich AM, Kaou M, Zhong Y, Johnson AJ, Lucas DM, Heerema NA, Hagan J, Mo X, Jarjoura D, Byrd JC, ... ... Jacob ST, et al. AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia. Blood. 118: 6132-40. PMID 22001392 DOI: 10.1182/Blood-2011-01-323147 |
0.382 |
|
| 2011 |
Wang B, Jacob ST. Role of cancer stem cells in hepatocarcinogenesis. Genome Medicine. 3: 11. PMID 21345246 DOI: 10.1186/Gm225 |
0.334 |
|
| 2011 |
Kaffenberger T, Roy S, Wang B, Costinean S, Frankel W, Bratasz A, Kuppusamy P, Hai T, Ghoshal K, Jacob S, Majumder S. Abstract 909: Activation of NF-κB and its downstream targets play a key role in the dramatic induction of hepatocarcinogenesis in metallothioneinnullmice Cancer Research. 71: 909-909. DOI: 10.1158/1538-7445.Am2011-909 |
0.381 |
|
| 2011 |
Hsu S, Wang B, Costinean S, Bai S, Kutay H, Yu L, Nuovo G, Jacob S, Ghoshal K. Abstract 2810: Loss of microRNA-122 in mice causes hepatic inflammation and hepatocarcinogenesis Cancer Research. 71: 2810-2810. DOI: 10.1158/1538-7445.Am2011-2810 |
0.783 |
|
| 2011 |
Motiwala T, Datta J, Kutay H, Roy S, Checovich A, Zanesi N, Kaou M, Johnson A, Hagan J, Byrd JC, Croce CM, Jacob ST. Abstract 276: Role of AP1 elements and TCL1 protein in regulation of the gene encoding PTPROt (protein tyrosine phosphatase receptor-type O) in chronic lymphocytic leukemia Cancer Research. 71: 276-276. DOI: 10.1158/1538-7445.Am2011-276 |
0.41 |
|
| 2011 |
Lu Y, Roy S, Miller T, Ghoshal K, Ramaswamy B, Shapiro C, Jacob ST, Majumder S. Abstract 1154: MicroRNA-221, -222 and -181 regulates tamoxifen resistance in breast cancer by downregulating TIMP3 and facilitating growth factor signaling Cancer Research. 71: 1154-1154. DOI: 10.1158/1538-7445.Am2011-1154 |
0.406 |
|
| 2010 |
Majumder S, Roy S, Kaffenberger T, Wang B, Costinean S, Frankel W, Bratasz A, Kuppusamy P, Hai T, Ghoshal K, Jacob ST. Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes. Cancer Research. 70: 10265-76. PMID 21159647 DOI: 10.1158/0008-5472.Can-10-2839 |
0.37 |
|
| 2010 |
Motiwala T, Datta J, Kutay H, Roy S, Jacob ST. Lyn kinase and ZAP70 are substrates of PTPROt in B-cells: Lyn inactivation by PTPROt sensitizes leukemia cells to VEGF-R inhibitor pazopanib. Journal of Cellular Biochemistry. 110: 846-56. PMID 20564182 DOI: 10.1002/Jcb.22593 |
0.32 |
|
| 2010 |
Ghoshal K, Motiwala T, Claus R, Yan P, Kutay H, Datta J, Majumder S, Bai S, Majumder A, Huang T, Plass C, Jacob ST. HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors. Plos One. 5: e10338. PMID 20454457 DOI: 10.1371/Journal.Pone.0010338 |
0.705 |
|
| 2010 |
Wang B, Hsu SH, Majumder S, Kutay H, Huang W, Jacob ST, Ghoshal K. TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene. 29: 1787-97. PMID 20023698 DOI: 10.1038/Onc.2009.468 |
0.719 |
|
| 2010 |
Majumder S, Alinari L, Roy S, Miller T, Datta J, Sif S, Baiocchi R, Jacob ST. Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription. Journal of Cellular Biochemistry. 109: 553-63. PMID 19998411 DOI: 10.1002/Jcb.22432 |
0.415 |
|
| 2009 |
Wang B, Majumder S, Nuovo G, Kutay H, Volinia S, Patel T, Schmittgen TD, Croce C, Ghoshal K, Jacob ST. Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice. Hepatology (Baltimore, Md.). 50: 1152-61. PMID 19711427 DOI: 10.1002/Hep.23100 |
0.422 |
|
| 2009 |
Datta J, Ghoshal K, Denny WA, Gamage SA, Brooke DG, Phiasivongsa P, Redkar S, Jacob ST. A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation. Cancer Research. 69: 4277-85. PMID 19417133 DOI: 10.1158/0008-5472.Can-08-3669 |
0.401 |
|
| 2009 |
Ramaswamy B, Majumder S, Roy S, Ghoshal K, Kutay H, Datta J, Younes M, Shapiro CL, Motiwala T, Jacob ST. Estrogen-mediated suppression of the gene encoding protein tyrosine phosphatase PTPRO in human breast cancer: mechanism and role in tamoxifen sensitivity. Molecular Endocrinology (Baltimore, Md.). 23: 176-87. PMID 19095770 DOI: 10.1210/Me.2008-0211 |
0.367 |
|
| 2009 |
Motiwala T, Majumder S, Ghoshal K, Kutay H, Datta J, Roy S, Lucas DM, Jacob ST. PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells. The Journal of Biological Chemistry. 284: 455-64. PMID 18997174 DOI: 10.1074/Jbc.M802840200 |
0.365 |
|
| 2008 |
Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T, Majumder S, Wang B, Suster S, Jacob ST, Ghoshal K. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. The Journal of Biological Chemistry. 283: 33394-405. PMID 18818206 DOI: 10.1074/Jbc.M804788200 |
0.396 |
|
| 2008 |
Miller TE, Ghoshal K, Ramaswamy B, Roy S, Datta J, Shapiro CL, Jacob S, Majumder S. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. The Journal of Biological Chemistry. 283: 29897-903. PMID 18708351 DOI: 10.1074/Jbc.M804612200 |
0.348 |
|
| 2008 |
Datta J, Kutay H, Nasser MW, Nuovo GJ, Wang B, Majumder S, Liu CG, Volinia S, Croce CM, Schmittgen TD, Ghoshal K, Jacob ST. Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Research. 68: 5049-58. PMID 18593903 DOI: 10.1158/0008-5472.Can-07-6655 |
0.453 |
|
| 2007 |
Ren C, Liu S, Ghoshal K, Hsu PH, Jacob ST, Marcucci G, Freitas MA. Simultaneous metabolic labeling of cells with multiple amino acids: Localization and dynamics of histone acetylation and methylation. Proteomics. Clinical Applications. 1: 130-42. PMID 21136616 DOI: 10.1002/Prca.200600631 |
0.325 |
|
| 2007 |
Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology. 133: 647-58. PMID 17681183 DOI: 10.1053/J.Gastro.2007.05.022 |
0.315 |
|
| 2007 |
Bai S, Datta J, Jacob ST, Ghoshal K. Treatment of PC12 cells with nerve growth factor induces proteasomal degradation of T-cadherin that requires tyrosine phosphorylation of its cadherin domain. The Journal of Biological Chemistry. 282: 27171-80. PMID 17631504 DOI: 10.1074/Jbc.M700691200 |
0.68 |
|
| 2007 |
Pal S, Baiocchi RA, Byrd JC, Grever MR, Jacob ST, Sif S. Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma. The Embo Journal. 26: 3558-69. PMID 17627275 DOI: 10.1038/Sj.Emboj.7601794 |
0.434 |
|
| 2007 |
Motiwala T, Majumder S, Kutay H, Smith DS, Neuberg DS, Lucas DM, Byrd JC, Grever M, Jacob ST. Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3174-81. PMID 17545520 DOI: 10.1158/1078-0432.Ccr-06-1720 |
0.405 |
|
| 2007 |
Datta J, Majumder S, Kutay H, Motiwala T, Frankel W, Costa R, Cha HC, MacDougald OA, Jacob ST, Ghoshal K. Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade. Cancer Research. 67: 2736-46. PMID 17363595 DOI: 10.1158/0008-5472.Can-06-4433 |
0.418 |
|
| 2007 |
Majumder S, Motiwala T, Ghoshal K, Kutay H, Datta J, Lucas D, Byrd JC, Jacob ST. Protein Tyrosine Phosphatase Receptor Type O (PTPRO) Exhibits Tumor Suppressor Properties in K562 Cells by Dephosphorylating Bcr-Abl. Blood. 110: 2914-2914. DOI: 10.1182/Blood.V110.11.2914.2914 |
0.363 |
|
| 2006 |
Kutay H, Bai S, Datta J, Motiwala T, Pogribny I, Frankel W, Jacob ST, Ghoshal K. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. Journal of Cellular Biochemistry. 99: 671-8. PMID 16924677 DOI: 10.1002/Jcb.20982 |
0.707 |
|
| 2006 |
Motiwala T, Jacob ST. Role of protein tyrosine phosphatases in cancer. Progress in Nucleic Acid Research and Molecular Biology. 81: 297-329. PMID 16891175 DOI: 10.1016/S0079-6603(06)81008-1 |
0.303 |
|
| 2006 |
Majumder S, Ghoshal K, Datta J, Smith DS, Bai S, Jacob ST. Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. The Journal of Biological Chemistry. 281: 22062-72. PMID 16735507 DOI: 10.1074/Jbc.M601155200 |
0.741 |
|
| 2006 |
Ghoshal K, Li X, Datta J, Bai S, Pogribny I, Pogribny M, Huang Y, Young D, Jacob ST. A folate- and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats. The Journal of Nutrition. 136: 1522-7. PMID 16702315 DOI: 10.1093/Jn/136.6.1522 |
0.714 |
|
| 2006 |
Bai S, Ghoshal K, Jacob ST. Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells. The Journal of Biological Chemistry. 281: 13604-11. PMID 16537533 DOI: 10.1074/Jbc.M513278200 |
0.707 |
|
| 2006 |
Majumder S, Kutay H, Datta J, Summers D, Jacob ST, Ghoshal K. Epigenetic regulation of metallothionein-i gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins. Journal of Cellular Biochemistry. 97: 1300-16. PMID 16329111 DOI: 10.1002/Jcb.20738 |
0.418 |
|
| 2005 |
Datta J, Majumder S, Bai S, Ghoshal K, Kutay H, Smith DS, Crabb JW, Jacob ST. Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells. Cancer Research. 65: 10891-900. PMID 16322236 DOI: 10.1158/0008-5472.Can-05-1455 |
0.725 |
|
| 2005 |
Ghoshal K, Datta J, Majumder S, Bai S, Kutay H, Motiwala T, Jacob ST. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal. Molecular and Cellular Biology. 25: 4727-41. PMID 15899874 DOI: 10.1128/Mcb.25.11.4727-4741.2005 |
0.719 |
|
| 2005 |
Jacob ST, Motiwala T. Epigenetic regulation of protein tyrosine phosphatases: potential molecular targets for cancer therapy. Cancer Gene Therapy. 12: 665-72. PMID 15803146 DOI: 10.1038/Sj.Cgt.7700828 |
0.406 |
|
| 2005 |
Bai S, Ghoshal K, Datta J, Majumder S, Yoon SO, Jacob ST. DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2. Molecular and Cellular Biology. 25: 751-66. PMID 15632075 DOI: 10.1128/Mcb.25.2.751-766.2005 |
0.711 |
|
| 2004 |
Motiwala T, Kutay H, Ghoshal K, Bai S, Seimiya H, Tsuruo T, Suster S, Morrison C, Jacob ST. Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 101: 13844-9. PMID 15356345 DOI: 10.1073/Pnas.0405451101 |
0.698 |
|
| 2004 |
Majumder S, Varadharaj S, Ghoshal K, Monani U, Burghes AH, Jacob ST. Identification of a novel cyclic AMP-response element (CRE-II) and the role of CREB-1 in the cAMP-induced expression of the survival motor neuron (SMN) gene. The Journal of Biological Chemistry. 279: 14803-11. PMID 14742439 DOI: 10.1074/Jbc.M308225200 |
0.378 |
|
| 2004 |
Ghoshal K, Majumder S, Datta J, Motiwala T, Bai S, Sharma SM, Frankel W, Jacob ST. Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression. The Journal of Biological Chemistry. 279: 6783-93. PMID 14610093 DOI: 10.1074/Jbc.M309393200 |
0.734 |
|
| 2004 |
Motiwala T, Ghoshal K, Majumder S, Kutay H, Neuberg DS, Kitada S, Reed JC, Dewald GW, Flinn IW, Tallman MA, Liu T, Plass C, Lucas DM, Byrd JC, Jacob ST, et al. Methylation of the Tumor Suppressor Gene PTPRO (Receptor-Type Protein Tyrosine Phosphatase) Is Associated with Expression of Important Apoptosis-Related Proteins in Chronic Lymphocytic Leukemia (CLL). Blood. 104: 2804-2804. DOI: 10.1182/Blood.V104.11.2804.2804 |
0.408 |
|
| 2003 |
Motiwala T, Ghoshal K, Das A, Majumder S, Weichenhan D, Wu YZ, Holman K, James SJ, Jacob ST, Plass C. Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas. Oncogene. 22: 6319-31. PMID 14508512 DOI: 10.1038/Sj.Onc.1206750 |
0.428 |
|
| 2003 |
Majumder S, Ghoshal K, Summers D, Bai S, Datta J, Jacob ST. Chromium(VI) down-regulates heavy metal-induced metallothionein gene transcription by modifying transactivation potential of the key transcription factor, metal-responsive transcription factor 1. The Journal of Biological Chemistry. 278: 26216-26. PMID 12716893 DOI: 10.1074/Jbc.M302887200 |
0.687 |
|
| 2003 |
Datta J, Ghoshal K, Sharma SM, Tajima S, Jacob ST. Biochemical fractionation reveals association of DNA methyltransferase (Dnmt) 3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1 Journal of Cellular Biochemistry. 88: 855-864. PMID 12616525 DOI: 10.1002/Jcb.10457 |
0.346 |
|
| 2002 |
Jacob ST, Majumder S, Ghoshal K. Suppression of metallothionein-I/II expression and its probable molecular mechanisms. Environmental Health Perspectives. 110: 827-30. PMID 12426140 DOI: 10.1289/Ehp.02110S5827 |
0.403 |
|
| 2002 |
Ghoshal K, Datta J, Majumder S, Bai S, Dong X, Parthun M, Jacob ST. Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. Molecular and Cellular Biology. 22: 8302-19. PMID 12417732 DOI: 10.1128/Mcb.22.23.8302-8319.2002 |
0.787 |
|
| 2002 |
Dong X, Ghoshal K, Majumder S, Yadav SP, Jacob ST. Mitochondrial transcription factor A and its downstream targets are up-regulated in a rat hepatoma. The Journal of Biological Chemistry. 277: 43309-18. PMID 12198131 DOI: 10.1074/Jbc.M206958200 |
0.731 |
|
| 2002 |
Ghoshal K, Majumder S, Jacob ST. Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells. Methods in Enzymology. 353: 476-86. PMID 12078520 DOI: 10.1016/S0076-6879(02)53070-6 |
0.361 |
|
| 2002 |
Majumder S, Ghoshal K, Datta J, Bai S, Dong X, Quan N, Plass C, Jacob ST. Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. The Journal of Biological Chemistry. 277: 16048-58. PMID 11844796 DOI: 10.1074/Jbc.M111662200 |
0.801 |
|
| 2001 |
Ghoshal K, Majumder S, Zhu Q, Hunzeker J, Datta J, Shah M, Sheridan JF, Jacob ST. Influenza virus infection induces metallothionein gene expression in the mouse liver and lung by overlapping but distinct molecular mechanisms. Molecular and Cellular Biology. 21: 8301-17. PMID 11713267 DOI: 10.1128/Mcb.21.24.8301-8317.2001 |
0.302 |
|
| 2000 |
Ghoshal K, Jacob ST. Regulation of metallothionein gene expression Progress in Nucleic Acid Research and Molecular Biology. 66: 357-384. PMID 11051769 DOI: 10.1016/S0079-6603(00)66034-8 |
0.351 |
|
| 2000 |
Ghoshal K, Majumder S, Li Z, Dong X, Jacob ST. Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation. The Journal of Biological Chemistry. 275: 539-47. PMID 10617649 DOI: 10.1074/Jbc.275.1.539 |
0.744 |
|
| 1999 |
Majumder S, Ghoshal K, Li Z, Bo Y, Jacob ST. Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation Oncogene. 18: 6287-6295. PMID 10597227 DOI: 10.1038/Sj.Onc.1203004 |
0.411 |
|
| 1999 |
Ghoshal K, Majumder S, Li Z, Bray TM, Jacob ST. Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice. Biochemical and Biophysical Research Communications. 264: 735-42. PMID 10544001 DOI: 10.1006/Bbrc.1999.1563 |
0.321 |
|
| 1999 |
Majumder S, Ghoshal K, Li Z, Jacob ST. Hypermethylation of metallothionein-I promoter and suppression of its induction in cell lines overexpressing the large subunit of Ku protein Journal of Biological Chemistry. 274: 28584-28589. PMID 10497224 DOI: 10.1074/Jbc.274.40.28584 |
0.417 |
|
| 1998 |
Ghoshal K, Li Z, Jacob ST. Overexpression of the large subunit of the protein Ku suppresses metallothionein-I induction by heavy metals Proceedings of the National Academy of Sciences of the United States of America. 95: 10390-10395. PMID 9724713 DOI: 10.1073/Pnas.95.18.10390 |
0.374 |
|
| 1997 |
Ghosh AK, Datta PK, Jacob ST. The dual role of helix - loop - helix-zipper protein USF in ribosomal RNA gene transcription in vivo Oncogene. 14: 589-594. PMID 9053857 DOI: 10.1038/Sj.Onc.1200866 |
0.385 |
|
| 1994 |
Niu H, Jacob ST. Enhancer 1 binding factor (E1BF), a Ku-related protein, is a growth-regulated RNA polymerase I transcription factor: Association of a repressor activity with purified E1BF from serum-deprived cells Proceedings of the National Academy of Sciences of the United States of America. 91: 9101-9105. PMID 8090777 DOI: 10.1073/Pnas.91.19.9101 |
0.366 |
|
| 1991 |
Zhang J, Niu H, Jacob ST. E1BF is an essential RNA polymerase I transcription factor with an intrinsic protein kinase activity that can modulate rRNA gene transcription Proceedings of the National Academy of Sciences of the United States of America. 88: 8293-8296. PMID 1924288 DOI: 10.1073/Pnas.88.19.8293 |
0.356 |
|
| 1987 |
Garg LC, DiAngelo S, Jacob ST. Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene Proceedings of the National Academy of Sciences of the United States of America. 84: 3185-3188. PMID 3033639 DOI: 10.1073/Pnas.84.10.3185 |
0.378 |
|
| 1986 |
Maguire KA, Jacob ST. Cell-free synthesis of tumor-type poly(A) polymerase. Biochemistry. 25: 1515-9. PMID 2423113 DOI: 10.1021/Bi00355A007 |
0.321 |
|
| 1985 |
Stetler DA, Jacob ST. Comparison of cytosolic and nuclear poly(A) polymerases from rat liver and a hepatoma: structural and immunological properties and response to NI-type protein kinases. Biochemistry. 24: 5163-9. PMID 3000424 DOI: 10.1021/Bi00340A031 |
0.311 |
|
| Show low-probability matches. |