Jeremy A. Squire - Publications

Affiliations: 
Queen's University, Kingston, ON, Canada 
Area:
Cancer genomics

319 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Harmon SA, Patel PG, Sanford TH, Caven I, Iseman R, Vidotto T, Picanço C, Squire JA, Masoudi S, Mehralivand S, Choyke PL, Berman DM, Turkbey B, Jamaspishvili T. High throughput assessment of biomarkers in tissue microarrays using artificial intelligence: PTEN loss as a proof-of-principle in multi-center prostate cancer cohorts. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 32884130 DOI: 10.1038/S41379-020-00674-W  0.323
2020 Brotto DB, Siena ÁDD, de Barros II, Carvalho SDCES, Muys BR, Goedert L, Cardoso C, Plaça JR, Ramão A, Squire JA, Araujo LF, Silva WAD. Contributions of HOX genes to cancer hallmarks: Enrichment pathway analysis and review. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 42: 1010428320918050. PMID 32456563 DOI: 10.1177/1010428320918050  0.345
2020 Vidotto T, Melo CM, Castelli E, Koti M, Reis RBD, Squire JA. Emerging role of PTEN loss in evasion of the immune response to tumours British Journal of Cancer. 122: 1732-1743. PMID 32327707 DOI: 10.1038/S41416-020-0834-6  0.327
2020 Jamaspishvili T, Patel PG, Niu Y, Vidotto T, Caven I, Livergant R, Fu W, Kawashima A, How N, Okello JB, Guedes LB, Ouellet V, Picanço C, Koti M, Reis RB, ... ... Squire JA, et al. Risk stratification of prostate cancer through quantitative assessment of PTEN loss (qPTEN). Journal of the National Cancer Institute. PMID 32129857 DOI: 10.1093/Jnci/Djaa032  0.339
2019 Joaquim TM, Grangeiro CHP, Gennaro FGdO, Gomes AG, Squire JA, Martelli LR. Partial Monosomy 4p and Trisomy 12q due to a t(4;12)(p16.3;q24.31) Familial Translocation in Two Cousins. Molecular Syndromology. 10: 264-271. PMID 32021597 DOI: 10.1159/000501923  0.416
2019 Vidotto T, Saggioro FP, Jamaspishvili T, Chesca DL, Picanço de Albuquerque CG, Reis RB, Graham CH, Berman DM, Siemens DR, Squire JA, Koti M. PTEN-deficient prostate cancer is associated with an immunosuppressive tumor microenvironment mediated by increased expression of IDO1 and infiltrating FoxP3+ T regulatory cells. The Prostate. PMID 30999388 DOI: 10.1002/Pros.23808  0.434
2019 Jamaspishvili T, Patel P, Niu Y, Vidotto T, Caven I, Livergant R, Fu W, Ouellet V, Picanço C, Koti M, How N, Saad F, Mes-Masson AM, Lotan T, Squire J, et al. MP28-02 QUANTITATIVE MEASUREMENT OF PTEN LOSS IMPROVES RISK ASSESSMENT IN PROSTATE CANCER. The Journal of Urology. 201: e403. PMID 30950708 DOI: 10.1097/01.Ju.0000555707.15264.F6  0.357
2019 Picanço-Albuquerque CG, Vidotto T, Pereira CS, Saggioro FP, Jamaspishvili T, Koti M, Berman DM, Squire JA, Reis RB. PTEN loss in Gleason grade 7 prostate tumors exhibits intratumoral heterogeneity and is associated with unfavorable pathological features Applied Cancer Research. 39: 1-6. DOI: 10.1186/S41241-018-0071-Y  0.425
2018 Ouellet V, Aprikian A, Bergeron A, Brimo F, Bristow RG, Chevalier S, Drachenberg D, Fazli L, Fleshner NE, Gleave M, Karakiewicz P, Klotz L, Lacombe L, Lattouf JB, van der Kwast T, ... Squire JA, et al. The Terry Fox Research Institute Canadian Prostate Cancer Biomarker Network: an analysis of a pan-Canadian multi-center cohort for biomarker validation. Bmc Urology. 18: 78. PMID 30200929 DOI: 10.1186/S12894-018-0392-X  0.316
2018 Jamaspishvili T, Berman DM, Ross AE, Scher HI, De Marzo AM, Squire JA, Lotan TL. Clinical implications of PTEN loss in prostate cancer. Nature Reviews. Urology. PMID 29460925 DOI: 10.1038/Nrurol.2018.9  0.384
2018 Yoshimoto M, Ludkovski O, Good J, Pereira C, Gooding RJ, McGowan-Jordan J, Boag A, Evans A, Tsao MS, Nuin P, Squire JA. Use of multicolor fluorescence in situ hybridization to detect deletions in clinical tissue sections. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29339834 DOI: 10.1038/S41374-017-0007-2  0.455
2018 Vidotto T, Tiezzi DG, Squire JA. Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer Molecular Cytogenetics. 11: 1-12. PMID 29308088 DOI: 10.1186/S13039-017-0348-Y  0.449
2018 Josahkian JA, Saggioro FP, Vidotto T, Ventura HT, Reis FJCd, Sousa CBd, Tiezzi DG, Andrade JMd, Koti M, Squire JA. Increased STAT1 Expression in High Grade Serous Ovarian Cancer Is Associated With a Better Outcome International Journal of Gynecological Cancer. 28: 459-465. PMID 29303938 DOI: 10.1097/Igc.0000000000001193  0.363
2018 Vidotto T, Squire JA, Koti M. Abstract B30: PTEN loss associates with type I and II IFN response in prostate cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Tcm17-B30  0.433
2018 Vidotto T, Koti M, Squire JA. Abstract 5736: In silico analysis shows that PTEN loss and AR overexpression are associated with increased CD8+ T-cell and Treg density and earlier disease recurrence in prostate cancer Cancer Research. 78: 5736-5736. DOI: 10.1158/1538-7445.Am2018-5736  0.378
2017 Pinheiro CA, Soares IC, Penna V, Squire J, Reis RMV, da Silva SRM, de Carvalho I, Camparoto ML, da Silva MFZ, Longatto Filho AL. Centrosome amplification in chondrosarcomas: A primary cell culture and cryopreserved tumor sample study. Oncology Letters. 13: 1835. PMID 28454331 DOI: 10.3892/Ol.2017.5633  0.398
2017 Galvão Gomes A, Paiva Grangeiro CH, Silva LR, Oliveira-Gennaro FG, Pereira CS, Joaquim TM, Panepucci RA, Squire JA, Martelli L. Complex Mosaic Ring Chromosome 11 Associated with Hemizygous Loss of 8.6 Mb of 11q24.2qter in Atypical Jacobsen Syndrome. Molecular Syndromology. 8: 45-49. PMID 28232783 DOI: 10.1159/000452681  0.422
2017 Vidotto T, Squire JA, Koti DVMM. PTEN loss affects the immune and inflammatory response in prostate cancer Semina-Ciencias Agrarias. 38: 229. DOI: 10.5433/1679-0367.2017V38N1Suplp229  0.416
2016 Lotan TL, Wei W, Ludkovski O, Morais CL, Guedes LB, Jamaspishvili T, Lopez K, Hawley ST, Feng Z, Fazli L, Hurtado-Coll A, McKenney JK, Simko J, Carroll PR, Gleave M, ... ... Squire JA, et al. Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27174589 DOI: 10.1038/Modpathol.2016.88  0.462
2016 Nawaz M, Fatima F, Nazarenko I, Ekström K, Murtaza I, Anees M, Sultan A, Neder L, Camussi G, Valadi H, Squire JA, Kislinger T. Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery. Expert Review of Proteomics. 13: 395-409. PMID 26973172 DOI: 10.1586/14789450.2016.1165613  0.32
2016 Picanço-Albuquerque CG, Morais CL, Carvalho FL, Peskoe SB, Hicks JL, Ludkovski O, Vidotto T, Fedor H, Humphreys E, Han M, Platz EA, De Marzo AM, Berman DM, Lotan TL, Squire JA. In prostate cancer needle biopsies, detections of PTEN loss by fluorescence in situ hybridization (FISH) and by immunohistochemistry (IHC) are concordant and show consistent association with upgrading. Virchows Archiv : An International Journal of Pathology. PMID 26861919 DOI: 10.1007/S00428-016-1904-2  0.435
2016 Weberpals JI, Amin MS, Chen BE, Tu D, Spaans JN, Squire JA, Eisenhauer EA, Virk S, Ma D, Duciaume M, Hoskins P, LeBrun DP. First application of the Automated QUantitative Analysis (AQUA) technique to quantify PTEN protein expression in ovarian cancer: A correlative study of NCIC CTG OV.16. Gynecologic Oncology. PMID 26775196 DOI: 10.1016/J.Ygyno.2016.01.015  0.384
2016 Vidotto T, Picanço-Albuquerque CG, Saggioro FP, Reis RBd, Siemens DR, Koti M, Squire JA. Abstract 716: STAT1 expression in the tumor-stroma microenvironment is influenced by loss of PTEN in prostate cancer Cancer Research. 76: 716-716. DOI: 10.1158/1538-7445.Am2016-716  0.438
2016 Au KK, Meunier L, Page CL, Graham CH, Craig AW, Childs T, Francis J, Squire J, Mes-Masson A, Koti M. Abstract 441: Association of interferon inducible genes with tumor immune microenvironment and chemotherapy resistance in high-grade serous epithelial ovarian cancer Cancer Research. 76: 441-441. DOI: 10.1158/1538-7445.Am2016-441  0.357
2015 Au KK, Josahkian JA, Francis JA, Squire JA, Koti M. Current state of biomarkers in ovarian cancer prognosis. Future Oncology (London, England). PMID 26551891 DOI: 10.2217/Fon.15.251  0.344
2015 Eigl BJ, North S, Winquist E, Finch D, Wood L, Sridhar SS, Powers J, Good J, Sharma M, Squire JA, Bazov J, Jamaspishvili T, Cox ME, Bradbury PA, Eisenhauer EA, et al. A phase II study of the HDAC inhibitor SB939 in patients with castration resistant prostate cancer: NCIC clinical trials group study IND195. Investigational New Drugs. PMID 25983041 DOI: 10.1007/S10637-015-0252-4  0.323
2015 Troyer DA, Jamaspishvili T, Wei W, Feng Z, Good J, Hawley S, Fazli L, McKenney JK, Simko J, Hurtado-Coll A, Carroll PR, Gleave M, Lance R, Lin DW, Nelson PS, ... ... Squire JA, et al. A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancer. The Prostate. 75: 1206-15. PMID 25939393 DOI: 10.1002/Pros.23003  0.406
2015 Powell K, Semaan L, Conley-LaComb MK, Asangani I, Wu YM, Ginsburg KB, Williams J, Squire JA, Maddipati KR, Cher ML, Chinni SR. ERG/AKR1C3/AR Constitutes a Feed-Forward Loop for AR Signaling in Prostate Cancer Cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2569-79. PMID 25754347 DOI: 10.1158/1078-0432.Ccr-14-2352  0.385
2015 Meyer M, Reimand J, Lan X, Head R, Zhu X, Kushida M, Bayani J, Pressey JC, Lionel AC, Clarke ID, Cusimano M, Squire JA, Scherer SW, Bernstein M, Woodin MA, et al. Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity. Proceedings of the National Academy of Sciences of the United States of America. 112: 851-6. PMID 25561528 DOI: 10.1073/pnas.1320611111  0.385
2015 Leduc C, Blandino II, Alhejaily A, Baetz T, Good DJ, Farmer PL, Squire JA, LeBrun DP. Composite mantle cell and primary cutaneous anaplastic large cell lymphoma: case report and review of the literature. The American Journal of Dermatopathology. 37: 232-6. PMID 25374307 DOI: 10.1097/Dad.0000000000000233  0.305
2015 Lotan TL, Carvalho FL, Peskoe SB, Hicks JL, Good J, Fedor HL, Humphreys E, Han M, Platz EA, Squire JA, De Marzo AM, Berman DM. PTEN loss is associated with upgrading of prostate cancer from biopsy to radical prostatectomy. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 28: 128-37. PMID 24993522 DOI: 10.1038/Modpathol.2014.85  0.428
2015 Lotan TL, Morais CL, Wei W, Jamaspishvili T, Feng Z, McKenney J, Simko J, Troyer D, True L, Brooks JD, Squire J, Biomarkers CPTIT. Mp1-17 Pten Status Determination In Prostate Cancer: Comparison Of Ihc And Fish In A Large Multi-Center Cohort The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.180  0.334
2015 Powell K, Semaan L, Conley-LaComb M, Asangani I, Wu Y, Williams J, Squire J, Maddipati K, Cher M, Chinni S. Mp37-02 Erg/Akr1C3/Ar Constitutes A Feed-Forward Loop For Ar Signaling In Prostate Cancer Cells The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.1265  0.303
2014 Lalonde E, Ishkanian AS, Sykes J, Fraser M, Ross-Adams H, Erho N, Dunning MJ, Halim S, Lamb AD, Moon NC, Zafarana G, Warren AY, Meng X, Thoms J, Grzadkowski MR, ... ... Squire JA, et al. Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study. The Lancet. Oncology. 15: 1521-32. PMID 25456371 DOI: 10.1016/S1470-2045(14)71021-6  0.353
2014 Williams JL, Greer PA, Squire JA. Recurrent copy number alterations in prostate cancer: an in silico meta-analysis of publicly available genomic data. Cancer Genetics. 207: 474-88. PMID 25434580 DOI: 10.1016/J.Cancergen.2014.09.003  0.494
2014 Pereira CS, Juchniuk de Vozzi MS, Dos Santos SA, Vasconcelos MA, de Paz CC, Squire JA, Martelli L. Smoking-induced chromosomal segregation anomalies identified by FISH analysis of sperm. Molecular Cytogenetics. 7: 58. PMID 25264457 DOI: 10.1186/S13039-014-0058-7  0.343
2014 Martin JW, Chilton-MacNeill S, Koti M, van Wijnen AJ, Squire JA, Zielenska M. Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma. Plos One. 9: e95843. PMID 24835790 DOI: 10.1371/Journal.Pone.0095843  0.39
2014 Carvalho FL, Lotan TL, Peskoe SB, Hicks J, Good J, Fedor HL, Humphreys EB, Han M, Platz E, Squire J, DeMarzo A, Berman DM. Association of PTEN protein loss with upgrading of prostate cancer from biopsy to radical prostatectomy. Journal of Clinical Oncology. 32: 127-127. DOI: 10.1200/Jco.2014.32.4_Suppl.127  0.409
2014 Koti M, Edwards A, Squire JA. Abstract 1106: The tumor immune microenvironment modulates response to chemotherapy in high-grade serous epithelial ovarian cancer Cancer Research. 74: 1106-1106. DOI: 10.1158/1538-7445.Am2014-1106  0.402
2014 Troyer D, Jamaspishvili T, Good J, Squire J, Wei W, Feng Z. Mp79-14 Fish Analysis Of 637 Prostate Cancers: Association Of Pten Genomic Deletion With Earlier Onset Of Disease Progression And Worse Prognosis The Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.2517  0.399
2013 Koti M, Gooding RJ, Nuin P, Haslehurst A, Crane C, Weberpals J, Childs T, Bryson P, Dharsee M, Evans K, Feilotter HE, Park PC, Squire JA. Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer. Bmc Cancer. 13: 549. PMID 24237932 DOI: 10.1186/1471-2407-13-549  0.326
2013 Dal Pra A, Lalonde E, Sykes J, Warde F, Ishkanian A, Meng A, Maloff C, Srigley J, Joshua AM, Petrovics G, van der Kwast T, Evans A, Milosevic M, Saad F, Collins C, ... Squire J, et al. TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: implications for fusion status and DSB repair. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5202-9. PMID 23918607 DOI: 10.1158/1078-0432.Ccr-13-1049  0.324
2013 Nagaria TS, Williams JL, Leduc C, Squire JA, Greer PA, Sangrar W. Flavopiridol synergizes with sorafenib to induce cytotoxicity and potentiate antitumorigenic activity in EGFR/HER-2 and mutant RAS/RAF breast cancer model systems. Neoplasia (New York, N.Y.). 15: 939-51. PMID 23908594 DOI: 10.1593/Neo.13804  0.31
2013 Tinker AV, Ellard S, Welch S, Moens F, Allo G, Tsao MS, Squire J, Tu D, Eisenhauer EA, MacKay H. Phase II study of temsirolimus (CCI-779) in women with recurrent, unresectable, locally advanced or metastatic carcinoma of the cervix. A trial of the NCIC Clinical Trials Group (NCIC CTG IND 199). Gynecologic Oncology. 130: 269-74. PMID 23672928 DOI: 10.1016/J.Ygyno.2013.05.008  0.302
2013 Oros KK, Arcand SL, Bayani J, Squire JA, Mes-Masson AM, Tonin PN, Greenwood CM. Analysis of genomic abnormalities in tumors: a review of available methods for Illumina two-color SNP genotyping and evaluation of performance. Cancer Genetics. 206: 103-15. PMID 23623180 DOI: 10.1016/J.Cancergen.2013.03.001  0.401
2013 Gamwell LF, Gambaro K, Merziotis M, Crane C, Arcand SL, Bourada V, Davis C, Squire JA, Huntsman DG, Tonin PN, Vanderhyden BC. Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics. Orphanet Journal of Rare Diseases. 8: 33. PMID 23433318 DOI: 10.1186/1750-1172-8-33  0.352
2013 Bayani J, Kuzmanov U, Saraon P, Fung WA, Soosaipillai A, Squire JA, Diamandis EP. Copy number and expression alterations of miRNAs in the ovarian cancer cell line OVCAR-3: impact on kallikrein 6 protein expression. Clinical Chemistry. 59: 296-305. PMID 23136250 DOI: 10.1373/Clinchem.2012.193060  0.319
2013 Yoshimoto M, Ding K, Sweet JM, Ludkovski O, Trottier G, Song KS, Joshua AM, Fleshner NE, Squire JA, Evans AJ. PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 26: 435-47. PMID 23018874 DOI: 10.1038/Modpathol.2012.162  0.311
2013 Koti M, Gooding RJ, Nuin P, Haslehurst A, Crane C, Weberpals J, Childs T, Bryson P, Dharsee M, Evans K, Feilotter HE, Park PC, Squire JA. Abstract 810: Integrative genomic and transcriptomic analysis in idenfitication of biomarkers of chemoresistance in serous epithelial ovarian cancer. Cancer Research. 73: 810-810. DOI: 10.1158/1538-7445.Am2013-810  0.448
2013 Yoshimoto M, Ludkovski O, Good J, Gooding RJ, McGowan-Jordan J, Boag A, Evans A, Tsao M, Nuin P, Squire JA. Abstract 63: Incorporation of flanking probes reduces truncation losses for fluorescence in situ hybridization analysis of recurrent genomic deletions in tumor sections. Cancer Research. 73: 63-63. DOI: 10.1158/1538-7445.Am2013-63  0.477
2013 Koti M, Gooding RJ, Nuin P, Haslehurst A, Crane C, Weberpals J, Chids T, Bryson P, Dharsee M, Evans KR, Feilotter HE, Park PC, Squire JA. Abstract A53: Biomarkers of chemotherapy resistance in serous epithelial ovarian cancer identified by integrative genomic and transcriptomic analysis Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-A53  0.434
2013 Boutros P, Lalonde E, Ishkanian A, Sykes J, Moon N, Zafarana G, Thoms J, Have L, Malloff C, Ramnarine V, Meng A, Mak D, Squire J, Jurisica I, Pintilie M, et al. MC13-0009 A prognostic CNA signature sub-stratifies intermediate-risk prostate cancer European Journal of Cancer. 49: S14. DOI: 10.1016/S0959-8049(13)70127-8  0.306
2013 Hossain D, Squire J, Yoshimoto M, Bostwick D. 2136 Application Of Four Color Fluorescence In Situ Hybridization Identifies Genomic Deletions Of The Pten Gene In 384 Of 2115 (18.2%) Diagnostic Prostate Cancer-Positive Needle Cores The Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.2045  0.407
2012 Dal Pra A, Warde F, Ishkanian AS, Meng A, Malloff C, Lam W, Sykes J, Pintile M, Squire J, van der Kwast T, Evans A, Milosevic M, Bristow RG. TMPRSS2-ERG status and biochemical recurrence following radiotherapy for intermediate-risk prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 11. PMID 27967837 DOI: 10.1200/Jco.2012.30.5_Suppl.11  0.338
2012 Cass JD, Varma S, Day AG, Sangrar W, Rajput AB, Raptis LH, Squire J, Madarnas Y, Sengupta SK, Elliott BE. Automated Quantitative Analysis of p53, Cyclin D1, Ki67 and pERK Expression in Breast Carcinoma Does Not Differ from Expert Pathologist Scoring and Correlates with Clinico-Pathological Characteristics. Cancers. 4: 725-42. PMID 24213463 DOI: 10.3390/Cancers4030725  0.339
2012 Choucair KA, Guérard KP, Ejdelman J, Chevalier S, Yoshimoto M, Scarlata E, Fazli L, Sircar K, Squire JA, Brimo F, Cunha IW, Aprikian A, Gleave M, Lapointe J. The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease Progression. Translational Oncology. 5: 453-60. PMID 23401739 DOI: 10.1593/Tlo.12286  0.401
2012 Yanagawa N, Leduc C, Kohler D, Saieg MA, John T, Sykes J, Yoshimoto M, Pintilie M, Squire J, Shepherd FA, Tsao MS. Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 1513-21. PMID 22982652 DOI: 10.1097/Jto.0B013E3182641D4F  0.342
2012 Girgis AH, Iakovlev VV, Beheshti B, Bayani J, Squire JA, Bui A, Mankaruos M, Youssef Y, Khalil B, Khella H, Pasic M, Yousef GM. Multilevel whole-genome analysis reveals candidate biomarkers in clear cell renal cell carcinoma. Cancer Research. 72: 5273-84. PMID 22926558 DOI: 10.1158/0008-5472.Can-12-0656  0.449
2012 Martin JW, Squire JA, Zielenska M. The genetics of osteosarcoma. Sarcoma. 2012: 627254. PMID 22685381 DOI: 10.1155/2012/627254  0.464
2012 Li M, Lockwood W, Zielenska M, Northcott P, Ra YS, Bouffet E, Yoshimoto M, Rutka JT, Yan H, Taylor MD, Eberhart C, Hawkins CE, Lam W, Squire JA, Huang A. Multiple CDK/CYCLIND genes are amplified in medulloblastoma and supratentorial primitive neuroectodermal brain tumor. Cancer Genetics. 205: 220-31. PMID 22682621 DOI: 10.1016/J.Cancergen.2012.03.002  0.411
2012 Pedeutour F, Maire G, Pierron A, Thomas DM, Garsed DW, Bianchini L, Duranton-Tanneur V, Cortes-Maurel A, Italiano A, Squire JA, Coindre JM. A newly characterized human well-differentiated liposarcoma cell line contains amplifications of the 12q12-21 and 10p11-14 regions. Virchows Archiv : An International Journal of Pathology. 461: 67-78. PMID 22678079 DOI: 10.1007/s00428-012-1256-5  0.38
2012 Haslehurst AM, Koti M, Dharsee M, Nuin P, Evans K, Geraci J, Childs T, Chen J, Li J, Weberpals J, Davey S, Squire J, Park PC, Feilotter H. EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer. Bmc Cancer. 12: 91. PMID 22429801 DOI: 10.1186/1471-2407-12-91  0.359
2012 Laus AC, Baratela WA, Laureano LA, Santos SA, Huber J, Ramos ES, Rebelo CC, Squire JA, Martelli L. Karyotype/phenotype correlation in partial trisomies of the long arm of chromosome 16: case report and review of literature. American Journal of Medical Genetics. Part A. 158: 821-7. PMID 22354628 DOI: 10.1002/Ajmg.A.32988  0.396
2012 Hakem A, El Ghamrasni S, Maire G, Lemmers B, Karaskova J, Jurisicova A, Sanchez O, Squire J, Hakem R. Caspase-8 is essential for maintaining chromosomal stability and suppressing B-cell lymphomagenesis. Blood. 119: 3495-502. PMID 22343728 DOI: 10.1182/Blood-2011-07-367532  0.373
2012 Zafarana G, Ishkanian AS, Malloff CA, Locke JA, Sykes J, Thoms J, Lam WL, Squire JA, Yoshimoto M, Ramnarine VR, Meng A, Ahmed O, Jurisica I, Jurisca I, Milosevic M, et al. Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy. Cancer. 118: 4053-62. PMID 22281794 DOI: 10.1002/Cncr.26729  0.44
2012 Bismar TA, Yoshimoto M, Duan Q, Liu S, Sircar K, Squire JA. Interactions and relationships of PTEN, ERG, SPINK1 and AR in castration-resistant prostate cancer. Histopathology. 60: 645-52. PMID 22260502 DOI: 10.1111/J.1365-2559.2011.04116.X  0.427
2012 Smith AC, Suzuki M, Thompson R, Choufani S, Higgins MJ, Chiu IW, Squire JA, Greally JM, Weksberg R. Maternal gametic transmission of translocations or inversions of human chromosome 11p15.5 results in regional DNA hypermethylation and downregulation of CDKN1C expression. Genomics. 99: 25-35. PMID 22079941 DOI: 10.1016/J.Ygeno.2011.10.007  0.428
2012 Locke JA, Zafarana G, Ishkanian AS, Milosevic M, Thoms J, Have CL, Malloff CA, Lam WL, Squire JA, Pintilie M, Sykes J, Ramnarine VR, Meng A, Ahmed O, Jurisica I, et al. NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 308-16. PMID 22048240 DOI: 10.1158/1078-0432.Ccr-11-2147  0.36
2012 Yoshimoto M, Ludkovski O, DeGrace D, Williams JL, Evans A, Sircar K, Bismar TA, Nuin P, Squire JA. PTEN genomic deletions that characterize aggressive prostate cancer originate close to segmental duplications. Genes, Chromosomes & Cancer. 51: 149-60. PMID 22045666 DOI: 10.1002/Gcc.20939  0.475
2012 Choucair K, Brimo F, Cunha IW, Aprikian A, Gleave M, Lapointe J, Guerard K, Ejdelman J, Chevalier S, Yoshimoto M, Scarlata E, Fazli L, Sircar K, Squire JA. Abstract C25: The 16p13.3 genomic gain in prostate cancer: A role for PDK1 in disease progression Cancer Research. 72: C25-C25. DOI: 10.1158/1538-7445.Prca2012-C25  0.458
2012 Koti M, Vidal R, Nuin P, Haslehurst A, Weberpals J, Childs T, Bryson P, Dharsee M, Evans K, Feilotter HE, Park PC, Squire JA. Abstract 3645: Integrative molecular profiling in serous epithelial ovarian cancer for identification of biomarkers of chemoresistance Cancer Research. 72: 3645-3645. DOI: 10.1158/1538-7445.Am2012-3645  0.406
2012 Vidal RS, Koti M, Kupchak P, Geraci J, Dharsee M, Haslehurst A, Childs T, Bryson P, Weberpals J, Park PC, Feilotter H, Squire JA, Nuin P. Abstract 3004: Biomarker identification through integrative bioinformatics analysis of serous epithelial ovarian cancer tumor samples Cancer Research. 72: 3004-3004. DOI: 10.1158/1538-7445.Am2012-3004  0.391
2012 Williams JL, Yoshimoto M, Nuin P, Greer PA, Squire JA. Abstract 1166:PTENloss andERGover-expression as prognostic biomarkers in prostate cancer and identification of downstream biomarkers with potential therapeutic value Cancer Research. 72: 1166-1166. DOI: 10.1158/1538-7445.Am2012-1166  0.457
2012 Eigl BJ, North S, Winquist E, Powers J, Good J, Sharma M, Squire J, Cox M, Eisenhauer EA, Chi K. A Phase II Study of SB939 in Patients (PTS) with Castration Resistant Prostate Cancer (CRPC) Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)33480-3  0.329
2011 Weberpals JI, Koti M, Squire JA. Targeting genetic and epigenetic alterations in the treatment of serous ovarian cancer. Cancer Genetics. 204: 525-35. PMID 22137482 DOI: 10.1016/J.Cancergen.2011.09.004  0.338
2011 Hakem A, Bohgaki M, Lemmers B, Tai E, Salmena L, Matysiak-Zablocki E, Jung YS, Karaskova J, Kaustov L, Duan S, Madore J, Boutros P, Sheng Y, Chesi M, Bergsagel PL, ... ... Squire J, et al. Role of Pirh2 in mediating the regulation of p53 and c-Myc. Plos Genetics. 7: e1002360. PMID 22125490 DOI: 10.1371/Journal.Pgen.1002360  0.307
2011 Squire JA, Park PC, Yoshimoto M, Alami J, Williams JL, Evans A, Joshua AM. Prostate cancer as a model system for genetic diversity in tumors. Advances in Cancer Research. 112: 183-216. PMID 21925305 DOI: 10.1016/B978-0-12-387688-1.00007-7  0.411
2011 Pandita A, Bayani J, Paderova J, Marrano P, Graham C, Barrett M, Prasad M, Zielenska M, Squire JA. Integrated cytogenetic and high-resolution array CGH analysis of genomic alterations associated with MYCN amplification. Cytogenetic and Genome Research. 134: 27-39. PMID 21508638 DOI: 10.1159/000324698  0.45
2011 Maire G, Martin JW, Yoshimoto M, Chilton-MacNeill S, Zielenska M, Squire JA. Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma. Cancer Genetics. 204: 138-46. PMID 21504713 DOI: 10.1016/J.Cancergen.2010.12.012  0.305
2011 Lockwood WW, Stack D, Morris T, Grehan D, O'Keane C, Stewart GL, Cumiskey J, Lam WL, Squire JA, Thomas DM, O'Sullivan MJ. Cyclin E1 is amplified and overexpressed in osteosarcoma. The Journal of Molecular Diagnostics : Jmd. 13: 289-96. PMID 21458381 DOI: 10.1016/J.Jmoldx.2010.11.020  0.423
2011 Li Y, Su J, DingZhang X, Zhang J, Yoshimoto M, Liu S, Bijian K, Gupta A, Squire JA, Alaoui Jamali MA, Bismar TA. PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome. The Journal of Pathology. 224: 90-100. PMID 21381033 DOI: 10.1002/Path.2855  0.382
2011 Weberpals JI, Tu D, Squire JA, Amin MS, Islam S, Pelletier LB, O'Brien AM, Hoskins PJ, Eisenhauer EA. Breast cancer 1 (BRCA1) protein expression as a prognostic marker in sporadic epithelial ovarian carcinoma: an NCIC CTG OV.16 correlative study. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 22: 2403-10. PMID 21368065 DOI: 10.1093/Annonc/Mdq770  0.341
2011 Martin JW, Zielenska M, Stein GS, van Wijnen AJ, Squire JA. The Role of RUNX2 in Osteosarcoma Oncogenesis. Sarcoma. 2011: 282745. PMID 21197465 DOI: 10.1155/2011/282745  0.353
2011 Liu S, Yoshimoto M, Trpkov K, Duan Q, Firszt M, Corcos J, Squire JA, Bismar TA. Detection of ERG gene rearrangements and PTEN deletions in unsuspected prostate cancer of the transition zone. Cancer Biology & Therapy. 11: 562-6. PMID 21178509 DOI: 10.4161/Cbt.11.6.14376  0.458
2011 Joshua AM, Shen E, Yoshimoto M, Marrano P, Zielenska M, Evans AJ, Van der Kwast T, Squire JA. Topographical analysis of telomere length and correlation with genomic instability in whole mount prostatectomies. The Prostate. 71: 778-90. PMID 21031437 DOI: 10.1002/Pros.21294  0.405
2011 Abou Youssif T, Fahmy MA, Koumakpayi IH, Ayala F, Al Marzooqi S, Chen G, Tamboli P, Squire J, Tanguay S, Sircar K. The mammalian target of rapamycin pathway is widely activated without PTEN deletion in renal cell carcinoma metastases. Cancer. 117: 290-300. PMID 20830770 DOI: 10.1002/Cncr.25402  0.34
2011 Bayani J, Marrano P, Graham C, Zheng Y, Li L, Katsaros D, Lassus H, Butzow R, Squire JA, Diamandis EP. Genomic instability and copy-number heterogeneity of chromosome 19q, including the kallikrein locus, in ovarian carcinomas. Molecular Oncology. 5: 48-60. PMID 20800559 DOI: 10.1016/J.Molonc.2010.08.002  0.494
2011 Bismar TA, Yoshimoto M, Vollmer RT, Duan Q, Firszt M, Corcos J, Squire JA. PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer. Bju International. 107: 477-85. PMID 20590547 DOI: 10.1111/J.1464-410X.2010.09470.X  0.441
2011 Joshua AM, Cockburn N, Evans A, Squire J, Yoshimoto M, Ludkovski O, Tan S, Dobi A, Furusato B, Petrovics G, Srivastava S, Sesterhenn I. Abstract 5074: Evaluation of PTEN and TMPRSS2-ERG abnormalities in prostate cancer by FISH and immunohistochemistry to address intra- and inter- tissue heterogeneity and disease progression Cancer Research. 71: 5074-5074. DOI: 10.1158/1538-7445.Am2011-5074  0.344
2011 Cass J, Varma S, Rajput A, Wang M, Day A, Sangrar W, Raptis L, Squire J, Madarnas Y, SenGupta S, Elliott B. Abstract 3207: Automated quantitative analysis of p53, cyclin D1 and pErk expression in breast carcinoma does not differ from expert pathologist scoring and correlates well with clinico-pathological characteristics Cancer Research. 71: 3207-3207. DOI: 10.1158/1538-7445.Am2011-3207  0.38
2011 Yoshimoto M, Evans A, Sweet J, Ludkovski O, Ding K, Trottier G, Song KS, Squire JA. Abstract 320: Association of higher Gleason grade with presence of PTEN deletion in prostatic adenocarcinoma Cancer Research. 71: 320-320. DOI: 10.1158/1538-7445.Am2011-320  0.503
2011 Ayala FRR, Cunha IWd, Yoshimoto M, Zielenska M, Squire JA, Soares FA. Abstract 317: 1q32.1 and 16q21 genomic alterations implicate KIF14/MDM4/PIK3C2ß and CDH11 as independent prognostic markers of relapse in localized Ewing Family of Tumors Cancer Research. 71: 317-317. DOI: 10.1158/1538-7445.Am2011-317  0.469
2011 Koti M, Vidal R, Haslehurst A, Nuin P, Weberpals J, Childs T, Bryson P, Feilotter H, Squire J, Park PC. Abstract 3155: Identification of biomarkers of chemoresistance in serous epithelial ovarian cancer by integrative molecular profiling Cancer Research. 71: 3155-3155. DOI: 10.1158/1538-7445.Am2011-3155  0.335
2011 Haslehurst A, Koti M, Vidal R, Park P, Jiang W, Squire J, Feilotter H. Abstract 1719: Integrative genomic analysis of ovarian cancer cell lines points to EMT involvement in the development of cisplatin resistance Cancer Research. 71: 1719-1719. DOI: 10.1158/1538-7445.Am2011-1719  0.332
2011 Bayani J, Kuzmanov U, Smith C, Batruch I, Presvelos J, Graham C, Squire JA, Diamandis EP. Abstract 1168: Integrated genomic, microRNA (miRNA) and proteomic profiling by stable isotope labeling with amino acids in cell culture (SILAC) of ovarian carcinoma for biomarker discovery Cancer Research. 71: 1168-1168. DOI: 10.1158/1538-7445.Am2011-1168  0.314
2011 Eigl BJ, North S, Murray N, Heng DY, Winquist E, Powers J, Walsh WR, Eisenhauer E, Squire J, Cox M, Chi KN. Abstract A221: A phase II study of SB939 in patients with recurrent or metastatic castration resistant prostate cancer (CRPC). Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-A221  0.345
2011 Joshua A, Evans A, Squire J, Yoshimoto M, Ludkovski O, Tan S, Dobi A, Furusato B, Petrovics G, Srivastava S, Sesterhenn I. 133 Evaluation Of Pten And Tmprss2-Erg Abnormalities In Prostate Cancer By Fish And Immunohistochemistry To Address Intra- And Inter- Tissue Heterogeneity And Disease Progression The Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.200  0.347
2011 Squire J, Ludkovski O, DeGrace D, Evans A, Sircar K, Bismar T, Yoshimoto M. 1607 High-Resolution Detection Of Pten Genomic Deletion By Fluorescence In Situ Hybridization (Fish) Using 330 Fixed Paraffin-Embedded Tissue Samples The Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1715  0.342
2010 Kulikowski LD, Yoshimoto M, da Silva Bellucco FT, Belangero SI, Christofolini DM, Pacanaro AN, Bortolai A, Smith Mde A, Squire JA, Melaragno MI. Cytogenetic molecular delineation of a terminal 18q deletion suggesting neo-telomere formation. European Journal of Medical Genetics. 53: 404-7. PMID 20837174 DOI: 10.1016/J.Ejmg.2010.08.007  0.412
2010 Veiga-Castelli LC, Silva JC, Meola J, Ferriani RA, Yoshimoto M, Santos SA, Squire JA, Martelli L. Genomic alterations detected by comparative genomic hybridization in ovarian endometriomas. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 43: 799-805. PMID 20725696 DOI: 10.1590/S0100-879X2010007500072  0.454
2010 Molyneux SD, Di Grappa MA, Beristain AG, McKee TD, Wai DH, Paderova J, Kashyap M, Hu P, Maiuri T, Narala SR, Stambolic V, Squire J, Penninger J, Sanchez O, Triche TJ, et al. Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice. The Journal of Clinical Investigation. 120: 3310-25. PMID 20697156 DOI: 10.1172/Jci42391  0.428
2010 Chung CT, Santos Gda C, Hwang DM, Ludkovski O, Pintilie M, Squire JA, Tsao MS. FISH assay development for the detection of p16/CDKN2A deletion in malignant pleural mesothelioma. Journal of Clinical Pathology. 63: 630-4. PMID 20591913 DOI: 10.1136/Jcp.2010.076794  0.326
2010 Lin D, Bayani J, Wang Y, Sadar MD, Yoshimoto M, Gout PW, Squire JA, Wang Y. Development of metastatic and non-metastatic tumor lines from a patient's prostate cancer specimen-identification of a small subpopulation with metastatic potential in the primary tumor. The Prostate. 70: 1636-44. PMID 20564316 DOI: 10.1002/Pros.21199  0.378
2010 Sadikovic B, Thorner P, Chilton-Macneill S, Martin JW, Cervigne NK, Squire J, Zielenska M. Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy. Bmc Cancer. 10: 202. PMID 20465837 DOI: 10.1186/1471-2407-10-202  0.41
2010 Martin JW, Yoshimoto M, Ludkovski O, Thorner PS, Zielenska M, Squire JA, Nuin PA. Analysis of segmental duplications, mouse genome synteny and recurrent cancer-associated amplicons in human chromosome 6p21-p12. Cytogenetic and Genome Research. 128: 199-213. PMID 20453501 DOI: 10.1159/000308353  0.415
2010 Rosario CO, Ko MA, Haffani YZ, Gladdy RA, Paderova J, Pollett A, Squire JA, Dennis JW, Swallow CJ. Plk4 is required for cytokinesis and maintenance of chromosomal stability. Proceedings of the National Academy of Sciences of the United States of America. 107: 6888-93. PMID 20348415 DOI: 10.1073/Pnas.0910941107  0.41
2010 Weberpals JI, Tu D, Squire J, Islam S, Amin S, Pelletier L, O'Brien A, Hoskins P, Eisenhauer EA. Breast cancer protein expression as a prognostic marker in sporadic epithelial ovarian cancer (EOC): An NCIC CTG OV.16 correlative study. Journal of Clinical Oncology. 28: 5018-5018. DOI: 10.1200/Jco.2010.28.15_Suppl.5018  0.309
2010 D'Silva CN, Yoshimoto M, Natalino R, Soares F, Antoneli C, Ribeiro K, Halliday W, Gallie BL, Squire JA. Abstract 4361: Retinoblastoma (RB) genomic progression analysis using Tissue Microarrays (TMA) comprising 121 RB patient tumors Cancer Research. 70: 4361-4361. DOI: 10.1158/1538-7445.Am10-4361  0.518
2010 Martin JW, Yoshimoto M, Chilton-MacNeill S, Thorner PS, Zielenska M, Squire JA. Abstract 3404: Identification of potential oncogenes in osteosarcoma pathogenesis by high-resolution array comparative genomic hybridization Cancer Research. 70: 3404-3404. DOI: 10.1158/1538-7445.Am10-3404  0.466
2010 Ayala FRR, Cunha IWd, Yoshimoto M, Zielenska M, Squire JA, Soares FA. Abstract 326: Prognostic value of KIF14 and MDM4 in Ewing's sarcoma Cancer Research. 70: 326-326. DOI: 10.1158/1538-7445.Am10-326  0.506
2010 Williams JL, Yoshimoto M, Ludkovski O, Kanishka S, Bismar T, Evans A, Squire JA. Abstract 320: Fine structure genomic mapping of chromosome 10q23 interstitial deletions in prostate cancer reveals thePTENgene locus as the minimum region deleted Cancer Research. 70: 320-320. DOI: 10.1158/1538-7445.Am10-320  0.497
2010 Bayani J, Kuzmanov U, Batruch I, Cho C, Smith C, Marrano P, Graham C, Butzow R, Katsaros D, Lin L, Zheng Y, Squire JA, Diamandis EP. Abstract 3037: Integrated Genomic, MicroRNA (miRNA) and Proteomic Profiling of Ovarian Carcinoma for Biomarker Discovery Cancer Research. 70: 3037-3037. DOI: 10.1158/1538-7445.Am10-3037  0.316
2010 Zafarana G, Ishkanian A, Maloff C, Thoms J, Squire J, Pintile M, Milosevic M, Lam W, Kvast Tvd, Bristow RG. Abstract 2136: Combined 8q gain and 10q loss predicts for relapse following radical radiotherapy in intermediate risk prostate cancer Cancer Research. 70: 2136-2136. DOI: 10.1158/1538-7445.Am10-2136  0.427
2009 Yoshimoto M, Graham C, Chilton-MacNeill S, Lee E, Shago M, Squire J, Zielenska M, Somers GR. Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC-DUX4 fusion gene event. Cancer Genetics and Cytogenetics. 195: 1-11. PMID 19837261 DOI: 10.1016/J.Cancergencyto.2009.06.015  0.453
2009 Fang Z, Soleymani L, Pampalakis G, Yoshimoto M, Squire JA, Sargent EH, Kelley SO. Direct profiling of cancer biomarkers in tumor tissue using a multiplexed nanostructured microelectrode integrated circuit. Acs Nano. 3: 3207-13. PMID 19736919 DOI: 10.1021/Nn900733D  0.384
2009 Lefebvre L, Mar L, Bogutz A, Oh-McGinnis R, Mandegar MA, Paderova J, Gertsenstein M, Squire JA, Nagy A. The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region. Human Molecular Genetics. 18: 4255-67. PMID 19684026 DOI: 10.1093/Hmg/Ddp379  0.338
2009 Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, Squire JA, Smith A, Dirks P. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell. 4: 568-80. PMID 19497285 DOI: 10.1016/J.Stem.2009.03.014  0.329
2009 Sircar K, Yoshimoto M, Monzon FA, Koumakpayi IH, Katz RL, Khanna A, Alvarez K, Chen G, Darnel AD, Aprikian AG, Saad F, Bismar TA, Squire JA. PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer. The Journal of Pathology. 218: 505-13. PMID 19402094 DOI: 10.1002/Path.2559  0.459
2009 Squire JA. TMPRSS2-ERG and PTEN loss in prostate cancer. Nature Genetics. 41: 509-10. PMID 19399032 DOI: 10.1038/Ng0509-509  0.363
2009 Ishkanian AS, Mallof CA, Ho J, Meng A, Albert M, Syed A, van der Kwast T, Milosevic M, Yoshimoto M, Squire JA, Lam WL, Bristow RG. High-resolution array CGH identifies novel regions of genomic alteration in intermediate-risk prostate cancer. The Prostate. 69: 1091-100. PMID 19350549 DOI: 10.1002/Pros.20959  0.319
2009 Sadikovic B, Yoshimoto M, Chilton-MacNeill S, Thorner P, Squire JA, Zielenska M. Identification of interactive networks of gene expression associated with osteosarcoma oncogenesis by integrated molecular profiling. Human Molecular Genetics. 18: 1962-75. PMID 19286668 DOI: 10.1093/Hmg/Ddp117  0.453
2009 Maire G, Yoshimoto M, Chilton-MacNeill S, Thorner PS, Zielenska M, Squire JA. Recurrent RECQL4 imbalance and increased gene expression levels are associated with structural chromosomal instability in sporadic osteosarcoma. Neoplasia (New York, N.Y.). 11: 260-8, 3p following . PMID 19242607 DOI: 10.1593/Neo.81384  0.48
2009 Chen CS, Squire JA, Wells PG. Reduced tumorigenesis in p53 knockout mice exposed in utero to low-dose vitamin E. Cancer. 115: 1563-75. PMID 19195043 DOI: 10.1002/Cncr.24130  0.342
2008 Sadikovic B, Al-Romaih K, Squire JA, Zielenska M. Cause and consequences of genetic and epigenetic alterations in human cancer. Current Genomics. 9: 394-408. PMID 19506729 DOI: 10.2174/138920208785699580  0.393
2008 Bayani J, Paliouras M, Planque C, Shan SJ, Graham C, Squire JA, Diamandis EP. Impact of cytogenetic and genomic aberrations of the kallikrein locus in ovarian cancer. Molecular Oncology. 2: 250-60. PMID 19383346 DOI: 10.1016/J.Molonc.2008.07.001  0.45
2008 Selvarajah S, Yoshimoto M, Ludkovski O, Park PC, Bayani J, Thorner P, Maire G, Squire JA, Zielenska M. Genomic signatures of chromosomal instability and osteosarcoma progression detected by high resolution array CGH and interphase FISH. Cytogenetic and Genome Research. 122: 5-15. PMID 18931480 DOI: 10.1159/000151310  0.402
2008 Bayani J, Paderova J, Murphy J, Rosen B, Zielenska M, Squire JA. Distinct patterns of structural and numerical chromosomal instability characterize sporadic ovarian cancer. Neoplasia (New York, N.Y.). 10: 1057-65. PMID 18813350 DOI: 10.1593/Neo.08584  0.459
2008 Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC, Khan F, Itie-Youten A, Wakeham A, Tsao MS, Iovanna JL, Squire J, Jurisica I, Kaplan D, Melino G, et al. TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes & Development. 22: 2677-91. PMID 18805989 DOI: 10.1101/Gad.1695308  0.382
2008 Sadikovic B, Yoshimoto M, Al-Romaih K, Maire G, Zielenska M, Squire JA. In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma. Plos One. 3: e2834. PMID 18698372 DOI: 10.1371/Journal.Pone.0002834  0.375
2008 Zhu CQ, da Cunha Santos G, Ding K, Sakurada A, Cutz JC, Liu N, Zhang T, Marrano P, Whitehead M, Squire JA, Kamel-Reid S, Seymour L, Shepherd FA, Tsao MS. Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 4268-75. PMID 18626007 DOI: 10.1200/Jco.2007.14.8924  0.321
2008 Lin D, Watahiki A, Bayani J, Zhang F, Liu L, Ling V, Sadar MD, English J, Fazli L, So A, Gout PW, Gleave M, Squire JA, Wang YZ. ASAP1, a gene at 8q24, is associated with prostate cancer metastasis. Cancer Research. 68: 4352-9. PMID 18519696 DOI: 10.1158/0008-5472.Can-07-5237  0.392
2008 Yoshimoto M, Joshua AM, Cunha IW, Coudry RA, Fonseca FP, Ludkovski O, Zielenska M, Soares FA, Squire JA. Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 1451-60. PMID 18500259 DOI: 10.1038/Modpathol.2008.96  0.453
2008 Al-Romaih K, Sadikovic B, Yoshimoto M, Wang Y, Zielenska M, Squire JA. Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells. Neoplasia (New York, N.Y.). 10: 471-80. PMID 18472964 DOI: 10.1593/Neo.08174  0.339
2008 Maire G, Brown CW, Bayani J, Pereira C, Gravel DH, Bell JC, Zielenska M, Squire JA. Complex rearrangement of chromosomes 19, 21, and 22 in Ewing sarcoma involving a novel reciprocal inversion-insertion mechanism of EWS-ERG fusion gene formation: a case analysis and literature review. Cancer Genetics and Cytogenetics. 181: 81-92. PMID 18295659 DOI: 10.1016/J.Cancergencyto.2007.11.002  0.484
2008 Prasad M, Bernardini M, Tsalenko A, Marrano P, Paderova J, Lee CH, Ben-Dor A, Barrett MT, Squire JA. High definition cytogenetics and oligonucleotide aCGH analyses of cisplatin-resistant ovarian cancer cells. Genes, Chromosomes & Cancer. 47: 427-36. PMID 18273836 DOI: 10.1002/Gcc.20547  0.458
2008 Dimaras H, Khetan V, Halliday W, Orlic M, Prigoda NL, Piovesan B, Marrano P, Corson TW, Eagle RC, Squire JA, Gallie BL. Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma. Human Molecular Genetics. 17: 1363-72. PMID 18211953 DOI: 10.1093/Hmg/Ddn024  0.456
2008 Joshua AM, Evans A, Van der Kwast T, Zielenska M, Meeker AK, Chinnaiyan A, Squire JA. Prostatic preneoplasia and beyond. Biochimica Et Biophysica Acta. 1785: 156-81. PMID 18166163 DOI: 10.1016/J.Bbcan.2007.12.001  0.386
2008 Oh R, Ho R, Mar L, Gertsenstein M, Paderova J, Hsien J, Squire JA, Higgins MJ, Nagy A, Lefebvre L. Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7. Molecular and Cellular Biology. 28: 1092-103. PMID 18039841 DOI: 10.1128/Mcb.01019-07  0.331
2007 Paderova J, Orlic-Milacic M, Yoshimoto M, da Cunha Santos G, Gallie B, Squire JA. Novel 6p rearrangements and recurrent translocation breakpoints in retinoblastoma cell lines identified by spectral karyotyping and mBAND analyses. Cancer Genetics and Cytogenetics. 179: 102-11. PMID 18036396 DOI: 10.1016/J.Cancergencyto.2007.08.014  0.423
2007 Selvarajah S, Yoshimoto M, Maire G, Paderova J, Bayani J, Squire JA, Zielenska M. Identification of cryptic microaberrations in osteosarcoma by high-definition oligonucleotide array comparative genomic hybridization. Cancer Genetics and Cytogenetics. 179: 52-61. PMID 17981215 DOI: 10.1016/J.Cancergencyto.2007.08.003  0.422
2007 Al-Romaih K, Somers GR, Bayani J, Hughes S, Prasad M, Cutz JC, Xue H, Zielenska M, Wang Y, Squire JA. Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells in vitro and in xenografts: identification of apoptotic genes as targets for demethylation. Cancer Cell International. 7: 14. PMID 17845729 DOI: 10.1186/1475-2867-7-14  0.342
2007 Yoshimoto M, Cunha IW, Coudry RA, Fonseca FP, Torres CH, Soares FA, Squire JA. FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome. British Journal of Cancer. 97: 678-85. PMID 17700571 DOI: 10.1038/Sj.Bjc.6603924  0.427
2007 Ghazani AA, Arneson N, Warren K, Pintilie M, Bayani J, Squire JA, Done SJ. Genomic alterations in sporadic synchronous primary breast cancer using array and metaphase comparative genomic hybridization. Neoplasia (New York, N.Y.). 9: 511-20. PMID 17603634 DOI: 10.1593/Neo.07301  0.441
2007 Yoshimoto M, Ludkovski O, Bayani J, Graham C, Zielenska M, Squire JA. Microdeletion and concurrent translocation associated with a complex TMPRSS2:ERG prostate cancer gene fusion. Genes, Chromosomes & Cancer. 46: 861-3. PMID 17584912 DOI: 10.1002/Gcc.20470  0.362
2007 Pang EY, Bai AH, To KF, Sy SM, Wong NL, Lai PB, Squire JA, Wong N. Identification of PFTAIRE protein kinase 1, a novel cell division cycle-2 related gene, in the motile phenotype of hepatocellular carcinoma cells. Hepatology (Baltimore, Md.). 46: 436-45. PMID 17559150 DOI: 10.1002/Hep.21691  0.414
2007 Dalla-Torre CA, de Toledo SR, Yoshimoto M, Petrilli AS, Andrade JA, Chilton-MacNeill S, Squire JA, Zielenska M. Expression of major vault protein gene in osteosarcoma patients. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 25: 958-63. PMID 17415755 DOI: 10.1002/Jor.20371  0.403
2007 Selvarajah S, Yoshimoto M, Prasad M, Shago M, Squire JA, Zielenska M, Somers GR. Characterization of trisomy 8 in pediatric undifferentiated sarcomas using advanced molecular cytogenetic techniques. Cancer Genetics and Cytogenetics. 174: 35-41. PMID 17350464 DOI: 10.1016/J.Cancergencyto.2006.11.011  0.447
2007 Joshua AM, Vukovic B, Braude I, Hussein S, Zielenska M, Srigley J, Evans A, Squire JA. Telomere attrition in isolated high-grade prostatic intraepithelial neoplasia and surrounding stroma is predictive of prostate cancer. Neoplasia (New York, N.Y.). 9: 81-9. PMID 17325746 DOI: 10.1593/Neo.06745  0.404
2007 Vukovic B, Beheshti B, Park P, Lim G, Bayani J, Zielenska M, Squire JA. Correlating breakage-fusion-bridge events with the overall chromosomal instability and in vitro karyotype evolution in prostate cancer. Cytogenetic and Genome Research. 116: 1-11. PMID 17268171 DOI: 10.1159/000097411  0.47
2007 Benoît MH, Hudson TJ, Maire G, Squire JA, Arcand SL, Provencher D, Mes-Masson AM, Tonin PN. Global analysis of chromosome X gene expression in primary cultures of normal ovarian surface epithelial cells and epithelial ovarian cancer cell lines. International Journal of Oncology. 30: 5-17. PMID 17143508 DOI: 10.3892/Ijo.30.1.5  0.436
2007 Snow BE, Mateyak M, Paderova J, Wakeham A, Iorio C, Zakian V, Squire J, Harrington L. Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo. Molecular and Cellular Biology. 27: 1017-26. PMID 17130244 DOI: 10.1128/Mcb.01866-06  0.331
2007 Ip WK, Lai PB, Wong NL, Sy SM, Beheshti B, Squire JA, Wong N. Identification of PEG10 as a progression related biomarker for hepatocellular carcinoma. Cancer Letters. 250: 284-91. PMID 17126992 DOI: 10.1016/J.Canlet.2006.10.012  0.353
2007 Bayani J, Selvarajah S, Maire G, Vukovic B, Al-Romaih K, Zielenska M, Squire JA. Genomic mechanisms and measurement of structural and numerical instability in cancer cells. Seminars in Cancer Biology. 17: 5-18. PMID 17126026 DOI: 10.1016/J.Semcancer.2006.10.006  0.405
2007 Bowles E, Corson TW, Bayani J, Squire JA, Wong N, Lai PB, Gallie BL. Profiling genomic copy number changes in retinoblastoma beyond loss of RB1. Genes, Chromosomes & Cancer. 46: 118-29. PMID 17099872 DOI: 10.1002/Gcc.20383  0.482
2007 Weksberg R, Stachon AC, Squire JA, Moldovan L, Bayani J, Meyn S, Chow E, Bassett AS. Molecular characterization of deletion breakpoints in adults with 22q11 deletion syndrome. Human Genetics. 120: 837-45. PMID 17028864 DOI: 10.1007/S00439-006-0242-X  0.318
2007 Santos GC, Zielenska M, Prasad M, Squire JA. Chromosome 6p amplification and cancer progression Journal of Clinical Pathology. 60: 1-7. PMID 16790693 DOI: 10.1136/Jcp.2005.034389  0.482
2007 Joshua A, Vukovic B, Braude I, Fleshner NE, Hussein S, Srigley J, Evans A, Zielenska M, Squire J. 654: Telomere Length Analysis of High-Grade Prostatic Intrapeithelial Neoplasia and Surrounding Stroma Predicts Outcome to Prostate Cancer The Journal of Urology. 177: 220-220. DOI: 10.1016/S0022-5347(18)30894-2  0.315
2007 Yoshimoto M, Cunha IW, Coudry RA, Fonseca FP, Torres CH, Soares FA, Squire JA. MP-17.17: FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome Urology. 70: 135. DOI: 10.1016/J.Urology.2007.06.504  0.382
2006 Kennedy JA, Barabé F, Patterson BJ, Bayani J, Squire JA, Barber DL, Dick JE. Expression of TEL-JAK2 in primary human hematopoietic cells drives erythropoietin-independent erythropoiesis and induces myelofibrosis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 103: 16930-5. PMID 17077140 DOI: 10.1073/Pnas.0604902103  0.328
2006 Dalla-Torre CA, Yoshimoto M, Lee CH, Joshua AM, de Toledo SR, Petrilli AS, Andrade JA, Chilton-MacNeill S, Zielenska M, Squire JA. Effects of THBS3, SPARC and SPP1 expression on biological behavior and survival in patients with osteosarcoma. Bmc Cancer. 6: 237. PMID 17022822 DOI: 10.1186/1471-2407-6-237  0.321
2006 Chan KYY, Lai PBS, Squire JA, Beheshti B, Wong NLY, Sy SMH, Wong N. Positional expression profiling indicates candidate genes in deletion hotspots of hepatocellular carcinoma Modern Pathology. 19: 1546-1554. PMID 16980951 DOI: 10.1038/Modpathol.3800674  0.432
2006 Yoshimoto M, Bayani J, Nuin PAS, Silva NS, Cavalheiro S, Stavale JN, Andrade JAD, Zielenska M, Squire JA, de Toledo SRC. Metaphase and array comparative genomic hybridization: unique copy number changes and gene amplification of medulloblastomas in South America Cancer Genetics and Cytogenetics. 170: 40-47. PMID 16965953 DOI: 10.1016/J.Cancergencyto.2006.05.009  0.474
2006 Yoshimoto M, Cutz JC, Nuin PAS, Joshua AM, Bayani J, Evans AJ, Zielenska M, Squire JA. Interphase FISH analysis of PTEN in histologic sections shows genomic deletions in 68% of primary prostate cancer and 23% of high-grade prostatic intra-epithelial neoplasias Cancer Genetics and Cytogenetics. 169: 128-137. PMID 16938570 DOI: 10.1016/J.Cancergencyto.2006.04.003  0.449
2006 Selvarajah S, Yoshimoto M, Park PC, Maire G, Paderova J, Bayani J, Lim G, Al-Romaih K, Squire JA, Zielenska M. The breakage-fusion-bridge (BFB) cycle as a mechanism for generating genetic heterogeneity in osteosarcoma Chromosoma. 115: 459-467. PMID 16897100 DOI: 10.1007/S00412-006-0074-4  0.45
2006 Yoshimoto M, Joshua AM, Chilton-MacNeill S, Bayani J, Selvarajah S, Evans AJ, Zielenska M, Squire JA. Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement Neoplasia. 8: 465-469. PMID 16820092 DOI: 10.1593/Neo.06283  0.463
2006 Cutz JC, Guan J, Bayani J, Yoshimoto M, Xue H, Sutcliffe M, English J, Flint J, LeRiche J, Yee J, Squire JA, Gout PW, Lam S, Wang YZ. Establishment in severe combined immunodeficiency mice of subrenal capsule xenografts and transplantable tumor lines from a variety of primary human lung cancers: potential models for studying tumor progression-related changes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4043-54. PMID 16818704 DOI: 10.1158/1078-0432.Ccr-06-0252  0.411
2006 Shuman C, Smith AC, Steele L, Ray PN, Clericuzio C, Zackai E, Parisi MA, Meadows AT, Kelly T, Tichauer D, Squire JA, Sadowski P, Weksberg R. Constitutional UPD for chromosome 11p15 in individuals with isolated hemihyperplasia is associated with high tumor risk and occurs following assisted reproductive technologies American Journal of Medical Genetics, Part A. 140: 1497-1503. PMID 16770802 DOI: 10.1002/Ajmg.A.31323  0.375
2006 Braude I, Vukovic B, Prasad M, Marrano P, Turley S, Barber D, Zielenska M, Squire JA. Large scale copy number variation (CNV) at 14q12 is associated with the presence of genomic abnormalities in neoplasia Bmc Genomics. 7. PMID 16756668 DOI: 10.1186/1471-2164-7-138  0.436
2006 Christofolini DM, Yoshimoto M, Squire JA, Brunoni D, Melaragno MI, Carvalheira G. Hydrocephaly, penoscrotal transposition, and digital anomalies associated with de novo pseudodicentric rearranged chromosome 13 characterized by classical cytogenetic methods and mBAND analysis American Journal of Medical Genetics, Part A. 140: 1321-1325. PMID 16691582 DOI: 10.1002/Ajmg.A.31269  0.425
2006 Tabori U, Vukovic B, Zielenska M, Hawkins C, Braude I, Rutka J, Bouffet E, Squire J, Malkin D. The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas. Neoplasia (New York, N.Y.). 8: 136-42. PMID 16611406 DOI: 10.1593/Neo.05715  0.391
2006 Hughes S, Yoshimoto M, Beheshti B, Houlston RS, Squire JA, Evans A. The use of whole genome amplification to study chromosomal changes in prostate cancer: Insights into genome-wide signature of preneoplasia associated with cancer progression Bmc Genomics. 7. PMID 16573809 DOI: 10.1186/1471-2164-7-65  0.412
2006 McPherson JP, Hande MP, Poonepalli A, Lemmers B, Zablocki E, Migon E, Shehabeldin A, Porras A, Karaskova J, Vukovic B, Squire J, Hakem R. A role for Brca1 in chromosome end maintenance. Human Molecular Genetics. 15: 831-8. PMID 16446310 DOI: 10.1093/Hmg/Ddl002  0.418
2006 Begley L, Keeney D, Beheshti B, Squire JA, Kant R, Chaib H, MacDonald JW, Rhim J, Macoska JA. Concordant copy number and transcriptional activity of genes mapping to derivative chromosomes 8 during cellular immortalization in vitro Genes Chromosomes and Cancer. 45: 136-146. PMID 16235240 DOI: 10.1002/Gcc.20274  0.455
2005 Bayani J, Squire JA. Detection of mitotic figures and components of the mitotic machinery. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 22.8. PMID 18228469 DOI: 10.1002/0471143030.Cb2208S25  0.386
2005 Bayani J, Squire JA. Comparative genomic hybridization. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 22.6. PMID 18228467 DOI: 10.1002/0471143030.Cb2206S25  0.387
2005 Li MH, Bouffet E, Hawkins CE, Squire JA, Huang A. Molecular genetics of supratentorial primitive neuroectodermal tumors and pineoblastoma Neurosurgical Focus [Electronic Resource].. 19: E3. PMID 16398467 DOI: 10.3171/Foc.2005.19.5.4  0.353
2005 Bayani J, Pandita A, Squire JA. Molecular cytogenetic analysis in the study of brain tumors: findings and applications Neurosurgical Focus [Electronic Resource].. 19: E1. PMID 16398459 DOI: 10.3171/Foc.2005.19.5.2  0.412
2005 Weksberg R, Hughes S, Moldovan L, Bassett AS, Chow EW, Squire JA. A method for accurate detection of genomic microdeletions using real-time quantitative PCR. Bmc Genomics. 6: 180. PMID 16351727 DOI: 10.1186/1471-2164-6-180  0.425
2005 Somers GR, Ho M, Zielenska M, Squire JA, Thorner PS. HER2 amplification and overexpression is not present in pediatric osteosarcoma: A tissue microarray study Pediatric and Developmental Pathology. 8: 525-532. PMID 16211448 DOI: 10.1007/S10024-005-0044-5  0.41
2005 Wang Y, Xue H, Cutz JC, Bayani J, Mawji NR, Chen WG, Goetz LJ, Hayward SW, Sadar MD, Gilks CB, Gout PW, Squire JA, Cunha GR, Wang YZ. An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 1392-404. PMID 16155594 DOI: 10.1038/Labinvest.3700335  0.363
2005 Bernardini M, Lee CH, Beheshti B, Prasad M, Albert M, Marrano P, Begley H, Shaw P, Covens A, Murphy J, Rosen B, Minkin S, Squire JA, Macgregor PF. High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer Neoplasia. 7: 603-613. PMID 16036111 DOI: 10.1593/Neo.04760  0.455
2005 Esteves LICV, Javaroni AC, Nishimoto IN, Magrin J, Squire JA, Kowalski LP, Rainho CA, Rogatto SR. DNA methylation in the CTCF-binding site I and the expression pattern of the H19 gene: Does positive expression predict poor prognosis in early stage head and neck carcinomas? Molecular Carcinogenesis. 44: 102-110. PMID 16015666 DOI: 10.1002/Mc.20126  0.323
2005 Tsao MS, Sakurada A, Cutz JC, Zhu CQ, Kamel-Reid S, Squire J, Lorimer I, Zhang T, Liu N, Daneshmand M, Marrano P, da Cunha Santos G, Lagarde A, Richardson F, Seymour L, et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. The New England Journal of Medicine. 353: 133-44. PMID 16014883 DOI: 10.1056/Nejmoa050736  0.339
2005 Scrideli CA, Baruffi MR, Squire JA, Ramos ES, Karaskova J, Heck B, Tone LG. Acute monocytic leukemia and multiple abnormalities in a child with duplication of 1q detected by GTG-banding and SKY Leukemia Research. 29: 1465-1467. PMID 15964069 DOI: 10.1016/J.Leukres.2005.04.022  0.415
2005 Pang E, Hu Y, Chan KYY, Lai PBS, Squire JA, Macgregor PF, Beheshti B, Albert M, Leung TWT, Wong N. Karyotypic imbalances and differential gene expressions in the acquired doxorubicin resistance of hepatocellular carcinoma cells Laboratory Investigation. 85: 664-674. PMID 15765123 DOI: 10.1038/Labinvest.3700254  0.303
2005 Lim G, Karaskova J, Beheshti B, Vukovic B, Bayani J, Selvarajah S, Watson SK, Lam WL, Zielenska M, Squire JA. An integrated mBAND and submegabase resolution tiling set (SMRT) CGH array analysis of focal amplification, microdeletions, and ladder structures consistent with breakage-fusion-bridge cycle events in osteosarcoma Genes Chromosomes and Cancer. 42: 392-403. PMID 15660435 DOI: 10.1002/Gcc.20157  0.47
2005 Chan KYY, Wong N, Lai PBS, Squire JA, Macgregor PF, Beheshti B, Albert M, To KF, Johnson PJ. Transcriptional profiling on chromosome 19p indicated frequent downregulation of ACP5 expression in hepatocellular carcinoma International Journal of Cancer. 114: 902-908. PMID 15645427 DOI: 10.1002/Ijc.20684  0.405
2005 Hughes S, Arneson N, Done S, Squire J. The use of whole genome amplification in the study of human disease. Progress in Biophysics and Molecular Biology. 88: 173-89. PMID 15561304 DOI: 10.1016/J.Pbiomolbio.2004.01.007  0.311
2004 Bayani J, Squire J. Multi-color FISH techniques Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. PMID 18228456 DOI: 10.1002/0471143030.Cb2205S24  0.369
2004 Bayani J, Squire JA. Fluorescence in situ Hybridization (FISH). Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 22.4. PMID 18228455 DOI: 10.1002/0471143030.Cb2204S23  0.326
2004 Bayani J, Squire JA. Traditional banding of chromosomes for cytogenetic analysis. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 22.3. PMID 18228454 DOI: 10.1002/0471143030.Cb2203S23  0.32
2004 Bayani J, Squire JA. Overview of cytogenetic chromosome analysis. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 22.1. PMID 18228452 DOI: 10.1002/0471143030.Cb2201S23  0.392
2004 Yoshimoto M, de Toledo SR, da Silva NS, Bayani J, Bertozzi AP, Stavale JN, Cavalheiro S, Andrade JA, Zielenska M, Squire JA. Comparative genomic hybridization analysis of pediatric adamantinomatous craniopharyngiomas and a review of the literature. Journal of Neurosurgery. 101: 85-90. PMID 16206977 DOI: 10.3171/Ped.2004.101.2.0085  0.439
2004 Fan R, Kumaravel TS, Jalali F, Marrano P, Squire JA, Bristow RG. Defective DNA strand break repair after DNA damage in prostate cancer cells: Implications for genetic instability and prostate cancer progression Cancer Research. 64: 8526-8533. PMID 15574758 DOI: 10.1158/0008-5472.Can-04-1601  0.365
2004 Hu Y, Pang E, Lai PBS, Squire JA, MacGregor PF, Beheshti B, Albert M, Leung TWT, Wong N. Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: a combined study of spectral karyotyping, positional expression profiling and candidate genes International Journal of Oncology. 25: 1357-1364. PMID 15492826 DOI: 10.3892/Ijo.25.5.1357  0.398
2004 MacOska JA, Paris P, Collins C, Andaya A, Beheshti B, Chaib H, Kant R, Begley L, MacDonald JW, Squire JA. Evolution of 8p loss in transformed human prostate epithelial cells Cancer Genetics and Cytogenetics. 154: 36-43. PMID 15381370 DOI: 10.1016/J.Cancergencyto.2004.02.013  0.429
2004 Lim G, Karaskova J, Vukovic B, Bayani J, Beheshti B, Bernardini M, Squire JA, Zielenska M. Combined spectral karyotyping, multicolor banding, and microarray comparative genomic hybridization analysis provides a detailed characterization of complex structural chromosomal rearrangements associated with gene amplification in the osteosarcoma cell line MG-63 Cancer Genetics and Cytogenetics. 153: 158-164. PMID 15350306 DOI: 10.1016/J.Cancergencyto.2004.01.016  0.464
2004 McPherson JP, Tamblyn L, Elia A, Migon E, Shehabeldin A, Matysiak-Zablocki E, Lemmers B, Salmena L, Hakem A, Fish J, Kassam F, Squire J, Bruneau BG, Hande MP, Hakem R. Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity. The Embo Journal. 23: 3677-88. PMID 15343267 DOI: 10.1038/Sj.Emboj.7600371  0.333
2004 Zielenska M, Marrano P, Thorner P, Pei J, Beheshti B, Ho M, Bayani J, Liu Y, Sun BC, Squire JA, Haod XS. High-resolution cDNA microarray CGH mapping of genomic imbalances in osteosarcoma using formalin-fixed paraffin-embedded tissue Cytogenetic and Genome Research. 107: 77-82. PMID 15305059 DOI: 10.1159/000079574  0.408
2004 Hughes S, Lim G, Beheshti B, Bayani J, Marrano P, Huang A, Squire JA. Use of whole genome amplification and comparative genomic hybridisation to detect chromosomal copy number alterations in cell line material and tumour tissue Cytogenetic and Genome Research. 105: 18-24. PMID 15218253 DOI: 10.1159/000078004  0.35
2004 McPherson JP, Lemmers B, Hirao A, Hakem A, Abraham J, Migon E, Matysiak-Zablocki E, Tamblyn L, Sanchez-Sweatman O, Khokha R, Squire J, Hande MP, Mak TW, Hakem R. Collaboration of Brca1 and Chk2 in tumorigenesis. Genes & Development. 18: 1144-53. PMID 15131084 DOI: 10.1101/Gad.1192704  0.351
2004 Evans AJ, Gallie BL, Jewett MAS, Pond GR, Vandezande K, Underwood J, Fradet Y, Lim G, Marrano P, Zielenska M, Squire JA. Defining a 0.5-Mb Region of Genomic Gain on Chromosome 6p22 in Bladder Cancer by Quantitative-Multiplex Polymerase Chain Reaction American Journal of Pathology. 164: 285-293. PMID 14695341 DOI: 10.1016/S0002-9440(10)63118-5  0.452
2004 Taylor MD, Raffel C, Bayani J, Marrano P, Mainprize TG, Squire J. Advanced cancer genetics in neurosurgical research. Neurosurgery. 53: 1168-78; discussion . PMID 14580285 DOI: 10.1227/01.Neu.0000088807.95566.9B  0.38
2003 Squire JA, Pei J, Marrano P, Beheshti B, Bayani J, Lim G, Moldovan L, Zielenska M. High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use of CGH analysis of cDNA microarrays Genes Chromosomes and Cancer. 38: 215-225. PMID 14506695 DOI: 10.1002/Gcc.10273  0.478
2003 Park PC, Taylor MD, Mainprize TG, Becker LE, Ho M, Dura WT, Squire J, Rutka JT. Transcriptional profiling of medulloblastoma in children. Journal of Neurosurgery. 99: 534-41. PMID 12959442 DOI: 10.3171/Jns.2003.99.3.0534  0.356
2003 Al-Romaih K, Bayani J, Vorobyova J, Karaskova J, Park PC, Zielenska M, Squire JA. Chromosomal instability in osteosarcoma and its association with centrosome abnormalities Cancer Genetics and Cytogenetics. 144: 91-99. PMID 12850370 DOI: 10.1016/S0165-4608(02)00929-9  0.447
2003 Kolomietz F, Marrano P, Yee K, Thai B, Braude I, Kolomietz A, Chun K, Minkin S, Kamel-Reid S, Minden M, Squire JA. Quantitative PCR identifies a minimal deleted region of 120 kb extending from the Philadelphia chromosome ABL translocation breakpoint in chronic myeloid leukemia with poor outcome Leukemia. 17: 1313-1323. PMID 12835719 DOI: 10.1038/Sj.Leu.2402969  0.333
2003 Nowaczyk MJM, Bayani J, Freeman V, Watts J, Squire J, Xu J. De novo 1q32q44 duplication and distal 1q trisomy syndrome American Journal of Medical Genetics Part A. 120: 229-233. PMID 12833404 DOI: 10.1002/Ajmg.A.20028  0.402
2003 Weksberg R, Smith AC, Squire J, Sadowski P. Beckwith-Wiedemann syndrome demonstrates a role for epigenetic control of normal development. Human Molecular Genetics. 12: R61-8. PMID 12668598 DOI: 10.1093/Hmg/Ddg067  0.397
2003 Beheshti B, Braude I, Marrano P, Thorner P, Zielenska M, Squire JA. Chromosomal localization of DNA amplifications in neuroblastoma tumors using cDNA microarray comparative genomic hybridization Neoplasia. 5: 53-62. PMID 12659670 DOI: 10.1016/S1476-5586(03)80017-9  0.457
2003 Gladdy RA, Taylor MD, Williams CJ, Grandal I, Karaskova J, Squire JA, Rutka JT, Guidos CJ, Danska JS. The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice. Cancer Cell. 3: 37-50. PMID 12559174 DOI: 10.1016/S1535-6108(02)00236-2  0.377
2003 Bayani J, Zielenska M, Pandita A, Al-Romaih K, Karaskova J, Harrison K, Bridge JA, Sorensen P, Thorner P, Squire JA. Spectral karyotyping identifies recurrent complex rearrangements of chromosomes 8, 17, and 20 in osteosarcomas Genes Chromosomes and Cancer. 36: 7-16. PMID 12461745 DOI: 10.1002/Gcc.10132  0.451
2003 Baruffi MR, Engel EE, Squire JA, Tone LG, Rogatto SR. Chromosomal imbalances detected in primary bone tumors by comparative genomic hybridization and interphase fluorescence in situ hybridization Genetics and Molecular Biology. 26: 107-113. DOI: 10.1590/S1415-47572003000200001  0.465
2002 Beheshti B, Vukovic B, Marrano P, Squire JA, Park PC. Resolution of genotypic heterogeneity in prostate tumors using polymerase chain reaction and comparative genomic hybridization on microdissected carcinoma and prostatic intraepithelial neoplasia foci Cancer Genetics and Cytogenetics. 137: 15-22. PMID 12377408 DOI: 10.1016/S0165-4608(02)00540-X  0.451
2002 Reis PP, Rogatto SR, Kowalski LP, Nishimoto IN, Montovani JC, Corpus G, Squire JA, Kamel-Reid S. Quantitative real-time PCR identifies a critical region of deletion on 22q13 related to prognosis in oral cancer. Oncogene. 21: 6480-7. PMID 12226751 DOI: 10.1038/Sj.Onc.1205864  0.453
2002 Squire JA, Bayani J, Luk C, Unwin L, Tokunaga J, MacMillan C, Irish J, Brown D, Gullane P, Kamel-Reid S. Molecular cytogenetic analysis of head and neck squamous cell carcinoma: By comparative genomic hybridization, spectral karyotyping, and expression array analysis. Head & Neck. 24: 874-87. PMID 12211052 DOI: 10.1002/Hed.10122  0.464
2002 Kolomietz E, Meyn MS, Pandita A, Squire JA. The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors Genes Chromosomes and Cancer. 35: 97-112. PMID 12203773 DOI: 10.1002/Gcc.10111  0.429
2002 Balakier H, Bouman D, Sojecki A, Librach C, Squire JA. Morphological and cytogenetic analysis of human giant oocytes and giant embryos Human Reproduction. 17: 2394-2401. PMID 12202430 DOI: 10.1093/Humrep/17.9.2394  0.326
2002 Macgregor PF, Squire JA. Application of microarrays to the analysis of gene expression in cancer Clinical Chemistry. 48: 1170-1177. PMID 12142369 DOI: 10.1093/Clinchem/48.8.1170  0.381
2002 Hattinger CM, Pötschger U, Tarkkanen M, Squire J, Zielenska M, Kiuru-Kuhlefelt S, Kager L, Thorner P, Knuutila S, Niggli FK, Ambros PF, Gadner H, Betts DR. Prognostic impact of chromosomal aberrations in Ewing tumours British Journal of Cancer. 86: 1763-1769. PMID 12087464 DOI: 10.1038/Sj.Bjc.6600332  0.412
2002 Chan AS, Thorner PS, Squire JA, Zielenska M. Identification of a novel gene NCRMS on chromosome 12q21 with differential expression between Rhabdomyosarcoma subtypes Oncogene. 21: 3029-3037. PMID 12082533 DOI: 10.1038/Sj.Onc.1205460  0.429
2002 Taylor MD, Liu L, Raffel C, Hui CC, Mainprize TG, Zhang X, Agatep R, Chiappa S, Gao L, Lowrance A, Hao A, Goldstein AM, Stavrou T, Scherer SW, Dura WT, ... ... Squire JA, et al. Mutations in SUFU predispose to medulloblastoma. Nature Genetics. 31: 306-10. PMID 12068298 DOI: 10.1038/Ng916  0.341
2002 Bayani J, Brenton JD, Macgregor PF, Beheshti B, Albert M, Nallainathan D, Karaskova J, Rosen B, Murphy J, Laframboise S, Zanke B, Squire JA. Parallel analysis of sporadic primary ovarian carcinomas by spectral karyotyping, comparative genomic hybridization, and expression microarrays Cancer Research. 62: 3466-3476. PMID 12067990  0.371
2002 Ojopi EPB, Cavalli LR, Cavalieri LMB, Squire JA, Rogatto SR. Comparative genomic hybridization analysis of benign and invasive male breast neoplasms Cancer Genetics and Cytogenetics. 134: 123-126. PMID 12034524 DOI: 10.1016/S0165-4608(01)00613-6  0.402
2002 Bayani JM, Squire JA. Applications of SKY in cancer cytogenetics Cancer Investigation. 20: 373-386. PMID 12025233 DOI: 10.1081/Cnv-120001183  0.486
2002 Weksberg R, Shuman C, Caluseriu O, Smith AC, Fei YL, Nishikawa J, Stockley TL, Best L, Chitayat D, Olney A, Ives E, Schneider A, Bestor TH, Li M, Sadowski P, ... Squire J, et al. Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith-Wiedemann syndrome. Human Molecular Genetics. 11: 1317-25. PMID 12019213 DOI: 10.1093/Hmg/11.11.1317  0.358
2002 Chen D, Pajovic S, Duckett A, Brown VD, Squire JA, Gallie BL. Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN Cancer Research. 62: 967-971. PMID 11861365  0.354
2002 Al-Maghrabi J, Vorobyova L, Toi A, Chapman W, Zielenska M, Squire JA. Identification of numerical chromosomal changes detected by interphase fluorescence in situ hybridization in high-grade prostate intraepithelial neoplasia as a predictor of carcinoma Archives of Pathology and Laboratory Medicine. 126: 165-169. PMID 11825111 DOI: 10.1043/0003-9985(2002)126<0165:Ionccd>2.0.Co;2  0.396
2002 Reis PPd, Rogatto SR, Kowalski LP, Nishimoto IN, Montovani JC, Corpus G, Squire JA, Kamel-Reid S. Quantitative real-time PCR reveals a region of deletion on 22q13 correlated to prognosis in oral cavity cancer International Journal of Cancer. 331-331. DOI: 10.1002/Ijc.9991/Abstract  0.367
2001 Smith AC, Squire JA, Thorner P, Zielenska M, Shuman C, Grant R, Chitayat D, Nishikawa JL, Weksberg R. Association of alveolar rhabdomyosarcoma with the Beckwith-Wiedemann syndrome. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 4: 550-8. PMID 11826361 DOI: 10.1007/S10024001-0110-6  0.388
2001 Taylor MD, Mainprize TG, Squire JA, Rutka JT. Molecular genetics of pineal region neoplasms. Journal of Neuro-Oncology. 54: 219-38. PMID 11767289 DOI: 10.1023/A:1012713506549  0.371
2001 Weksberg R, Nishikawa J, Caluseriu O, Fei YL, Shuman C, Wei C, Steele L, Cameron J, Smith A, Ambus I, Li M, Ray PN, Sadowski P, Squire J. Tumor development in the Beckwith-Wiedemann syndrome is associated with a variety of constitutional molecular 11p15 alterations including imprinting defects of KCNQ1OT1. Human Molecular Genetics. 10: 2989-3000. PMID 11751681 DOI: 10.1093/Hmg/10.26.2989  0.384
2001 Al-Maghrabi J, Vorobyova L, Chapman W, Jewett M, Zielenska M, Squire JA. p53 alteration and chromosomal instability in prostatic high-grade intraepithelial neoplasia and concurrent carcinoma: Analysis by immunohistochemistry, interphase in situ hybridization, and sequencing of laser-captured microdissected specimens Modern Pathology. 14: 1252-1262. PMID 11743048 DOI: 10.1038/Modpathol.3880471  0.396
2001 Zielenska M, Bayani J, Pandita A, Toledo S, Marrano P, Andrade J, Petrilli A, Thorner P, Sorensen P, Squire JA. Comparative genomic hybridization analysis identifies gains of 1p35∼p36 and chromosome 19 in osteosarcoma Cancer Genetics and Cytogenetics. 130: 14-21. PMID 11672768 DOI: 10.1016/S0165-4608(01)00461-7  0.482
2001 Chen D, Gallie BL, Squire JA. Minimal regions of chromosomal imbalance in retinoblastoma detected by comparative genomic hybridization Cancer Genetics and Cytogenetics. 129: 57-63. PMID 11520568 DOI: 10.1016/S0165-4608(01)00427-7  0.481
2001 Li M, Shuman C, Fei YL, Cutiongco E, Bender HA, Stevens C, Wilkins-Haug L, Day-Salvatore D, Yong SL, Geraghty MT, Squire J, Weksberg R. GPC3 mutation analysis in a spectrum of patients with overgrowth expands the phenotype of Simpson-Golabi-Behmel syndrome. American Journal of Medical Genetics. 102: 161-8. PMID 11477610 DOI: 10.1002/1096-8628(20010801)102:2<161::Aid-Ajmg1453>3.0.Co;2-O  0.317
2001 Squire JA, Arab S, Marrano P, Bayani J, Karaskova J, Taylor M, Becker L, Rutka J, Zielenska M. Molecular cytogenetic analysis of glial tumors using spectral karyotyping and comparative genomic hybridization Molecular Diagnosis. 6: 93-108. PMID 11468694 DOI: 10.1054/Modi.2001.22745  0.422
2001 Ma Z, Morris SW, Valentine V, Li M, Herbrick JA, Cui X, Bouman D, Li Y, Mehta PK, Nizetic D, Kaneko Y, Chan GC, Chan LC, Squire J, Scherer SW, et al. Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nature Genetics. 28: 220-1. PMID 11431691 DOI: 10.1038/90054  0.346
2001 Li M, Squire J, Shuman C, Fei YL, Atkin J, Pauli R, Smith A, Nishikawa J, Chitayat D, Weksberg R. Imprinting status of 11p15 genes in Beckwith-Wiedemann syndrome patients with CDKN1C mutations. Genomics. 74: 370-6. PMID 11414765 DOI: 10.1006/Geno.2001.6549  0.324
2001 Zielenska M, Zhang ZM, Ng K, Marrano P, Bayani J, Ramirez OC, Sorensen P, Thorner P, Greenberg M, Squire JA. Acquisition of secondary structural chromosomal changes in pediatric ewing sarcoma is a probable prognostic factor for tumor response and clinical outcome. Cancer. 91: 2156-64. PMID 11391597 DOI: 10.1002/1097-0142(20010601)91:11<2156::Aid-Cncr1244>3.0.Co;2-I  0.474
2001 Kolomietz E, Al-Maghrabi J, Brennan S, Karaskova J, Minkin S, Lipton J, Squire JA. Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis Blood. 97: 3581-3588. PMID 11369654 DOI: 10.1182/blood.V97.11.3581  0.301
2001 Luk C, Tsao MS, Bayani J, Shepherd F, Squire JA. Molecular cytogenetic analysis of non-small cell lung carcinoma by spectral karyotyping and comparative genomic hybridization Cancer Genetics and Cytogenetics. 125: 87-99. PMID 11369051 DOI: 10.1016/S0165-4608(00)00363-0  0.428
2001 Beheshti B, Park PC, Sweet JM, Trachtenberg J, Jewett MA, Squire JA. Evidence of chromosomal instability in prostate cancer determined by spectral karyotyping (SKY) and interphase fish analysis. Neoplasia (New York, N.Y.). 3: 62-9. PMID 11326317 DOI: 10.1038/Sj.Neo.7900125  0.466
2001 Lefebvre L, Dionne N, Karaskova J, Squire JA, Nagy A. Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity. Nature Genetics. 27: 257-8. PMID 11242104 DOI: 10.1038/85808  0.342
2001 Ojopi EPB, Rogatto SR, Caldeira JRF, Barbieri-Neto J, Squire JA. Comparative genomic hybridization detects novel amplifications in fibroadenomas of the breast Genes Chromosomes and Cancer. 30: 25-31. PMID 11107172 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1057>3.0.Co;2-D  0.371
2001 Chen D, Squire J, Gallie B. Genomic amplification in retinoblastoma narrowed to 1.2 Mb on chromosome 6p containing a novel kinesin-like gene, RBKIN Nature Genetics. 27: 46-46. DOI: 10.1038/87028  0.435
2000 Ouyang H, Mou L, Luk C, Liu N, Karaskova J, Squire J, Tsao M. Immortal Human Pancreatic Duct Epithelial Cell Lines with Near Normal Genotype and Phenotype American Journal of Pathology. 157: 1623-1631. PMID 11073822 DOI: 10.1016/S0002-9440(10)64800-6  0.351
2000 Balakier H, Cabaca O, Bouman D, Shewchuk AB, Laskin C, Squire JA. Spontaneous blastomere fusion after freezing and thawing of early human embryos leads to polyploidy and chromosomal mosaicism Human Reproduction. 15: 2404-2410. PMID 11056142 DOI: 10.1093/Humrep/15.11.2404  0.352
2000 Bayani J, Zielenska M, Marrano P, Kwan Ng Y, Taylor MD, Jay V, Rutka JT, Squire JA. Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping. Journal of Neurosurgery. 93: 437-48. PMID 10969942 DOI: 10.3171/Jns.2000.93.3.0437  0.483
2000 Poli-Frederico RC, Bergamo NA, Reis PP, Kowalski LP, Zielenska M, Squire JA, Rogatto SR. Chromosome 22q a frequent site of allele loss in head and neck carcinoma Head and Neck. 22: 585-590. PMID 10941160 DOI: 10.1002/1097-0347(200009)22:6<585::Aid-Hed7>3.0.Co;2-4  0.461
2000 Macoska JA, Beheshti B, Rhim JS, Hukku B, Lehr J, Pienta KJ, Squire JA. Genetic characterization of immortalized human prostate epithelial cell cultures: Evidence for structural rearrangements of chromosome 8 and i(8q) chromosome formation in primary tumor-derived cells Cancer Genetics and Cytogenetics. 120: 50-57. PMID 10913677 DOI: 10.1016/S0165-4608(99)00248-4  0.341
2000 Barnard M, Bayani J, Grant R, Teshima I, Thorner P, Squire J. Use of Multicolor Spectral Karyotyping in Genetic Analysis of Pleuropulmonary Blastoma Pediatric and Developmental Pathology. 3: 479-486. PMID 10890933 DOI: 10.1007/S100240010094  0.458
2000 Mak TW, Hakem A, McPherson JP, Shehabeldin A, Zablocki E, Migon E, Duncan GS, Bouchard D, Wakeham A, Cheung A, Karaskova J, Sarosi I, Squire J, Marth J, Hakem R. Brca1 required for T cell lineage development but not TCR loci rearrangement. Nature Immunology. 1: 77-82. PMID 10881179 DOI: 10.1038/76950  0.313
2000 Squire JA, Li M, Perlikowski S, Fei YL, Bayani J, Zhang ZM, Weksberg R. Alterations of H19 imprinting and IGF2 replication timing are infrequent in Beckwith-Wiedemann syndrome Genomics. 65: 234-242. PMID 10857747 DOI: 10.1006/Geno.2000.6155  0.35
2000 Squire J. Identification of a high frequency of chromosomal rearrangements in the centromeric regions of prostate cancer cell lines by sequential Giemsa banding and spectral karyotyping Molecular Diagnosis. 5: 23-32. PMID 10837086 DOI: 10.1016/S1084-8592(00)00007-2  0.437
2000 Bergamo NA, Rogatto SR, Poli-Frederico RC, Reis PP, Kowalski LP, Zielenska M, Squire JA. Comparative genomic hybridization analysis detects frequent over- representation of DNA sequences at 3q, 7p, and 8q in head and neck carcinomas Cancer Genetics and Cytogenetics. 119: 48-55. PMID 10812171 DOI: 10.1016/S0165-4608(99)00213-7  0.433
2000 Safar A, Nelson M, Neff JR, Maale GE, Bayani J, Squire J, Bridge JA. Recurrent anomalies of 6q25 in chondromyxoid fibroma Human Pathology. 31: 306-311. PMID 10746672 DOI: 10.1016/S0046-8177(00)80243-9  0.418
2000 Barnard M, Bayani J, Grant R, Zielenska M, Squire J, Thorner P. Comparative genomic hybridization analysis of clear cell sarcoma of the kidney. Medical and Pediatric Oncology. 34: 113-116. PMID 10657872 DOI: 10.1002/(Sici)1096-911X(200002)34:2<113::Aid-Mpo8>3.0.Co;2-N  0.473
2000 Boehm AK, Neff JR, Squire JA, Bayani J, Nelson M, Bridge JA. Cytogenetic findings in 36 osteosarcoma specimens and a review of the literature Pediatric Pathology and Molecular Medicine. 19: 359-376. DOI: 10.1080/15513810009168645  0.438
1999 Pandita A, Zielenska M, Thorner P, Bayani J, Godbout R, Greenberg M, Squire JA. Application of comparative genomic hybridization, spectral karyotyping, and microarray analysis in the identification of subtype-specific patterns of genomic changes in rhabdomyosarcoma. Neoplasia (New York, N.Y.). 1: 262-75. PMID 10935481 DOI: 10.1038/Sj.Neo.7900036  0.506
1999 Jay V, Squire J, Bayani J, Alkhani AM, Rutka JT, Zielenska M. Oncogene amplification in medulloblastoma: analysis of a case by comparative genomic hybridization and fluorescence in situ hybridization. Pathology. 31: 337-44. PMID 10643003 DOI: 10.1080/003130299104693  0.491
1999 Simons J, Teshima I, Zielenska M, Edwards V, Taylor G, Squire J, Thorner P. Analysis of chromosome 22q as an aid to the diagnosis of rhabdoid tumor : A case report The American Journal of Surgical Pathology. 23: 982-988. PMID 10435570 DOI: 10.1097/00000478-199908000-00018  0.398
1999 Dimitroulakos J, Pienkowska M, Sun P, Farooq S, Zielenska M, Squire JA, Yeger H. Identification of a novel zinc finger gene, zf5-3, as a potential mediator of neuroblastoma differentiation International Journal of Cancer. 81: 970-978. PMID 10362147 DOI: 10.1002/(Sici)1097-0215(19990611)81:6<970::Aid-Ijc21>3.0.Co;2-9  0.383
1999 Rogatto SR, Rainho CA, Zhang ZM, Figueiredo F, Barbieri-Neto J, Georgetto SM, Squire JA. Hemangioendothelioma of bone in a patient with a constitutional supernumerary marker. Cancer Genetics and Cytogenetics. 110: 23-27. PMID 10198618 DOI: 10.1016/S0165-4608(98)00192-7  0.441
1999 Chang H, Bouman D, Boerkoel CF, Stewart AK, Squire JA. Frequent monoallelic loss of D13S319 in multiple myeloma patients shown by interphase fluorescence in situ hybridization Leukemia. 13: 105-109. PMID 10049044 DOI: 10.1038/Sj.Leu.2401208  0.457
1999 Vaziri H, Squire JA, Pandita TK, Bradley G, Kuba RM, Zhang H, Gulyas S, Hill RP, Nolan GP, Benchimol S. Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts Molecular and Cellular Biology. 19: 2373-2379. PMID 10022923 DOI: 10.1128/Mcb.19.3.2373  0.351
1999 Chan AS, MacNeill S, Thorner P, Squire J, Zielenska M. Variant EWS-WT1 Chimeric Product in the Desmoplastic Small Round Cell Tumor Pediatric and Developmental Pathology. 2: 188-192. PMID 9949226 DOI: 10.1007/S100249900108  0.458
1999 Thorner P, Squire J, Plavsic N, Jong R, Greenberg M, Zielenska M. Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin. Pediatric and Developmental Pathology. 2: 33-41. PMID 9841704 DOI: 10.1007/S100249900087  0.37
1999 Bayani J, Pandita A, Squire JA. Sequential G-banding, SKY and FISH provide a refined identification of translocation breakpoints and complex chromosomal rearrangements Technical Tips Online. 4: 66-69. DOI: 10.1016/S1366-2120(08)70142-9  0.324
1998 Khoddami M, Squire J, Zielenska M, Thorner P. Melanotic neuroectodermal tumor of infancy: a molecular genetic study. Pediatric and Developmental Pathology. 1: 295-299. PMID 10463291 DOI: 10.1007/S100249900042  0.387
1998 Li M, Squire JA, Weksberg R. Molecular genetics of Wiedemann-Beckwith syndrome. American Journal of Medical Genetics. 79: 253-259. PMID 9781904 DOI: 10.1002/(Sici)1096-8628(19981002)79:4<253::Aid-Ajmg5>3.0.Co;2-N  0.337
1998 Thorner PS, Squire JA. Molecular genetics in the diagnosis and prognosis of solid pediatric tumors Pediatric and Developmental Pathology. 1: 337-365. PMID 9688759 DOI: 10.1007/S100249900049  0.372
1998 Luo L, Herbrick JA, Scherer SW, Beatty B, Squire J, Diamandis EP. Structural characterization and mapping of the normal epithelial cell-specific 1 gene. Biochemical and Biophysical Research Communications. 247: 580-6. PMID 9647736 DOI: 10.1006/Bbrc.1998.8793  0.418
1998 Chan AS, Squire JA, Thorner P, Zielenska M. Molecular Genetic Changes in Alveolar Soft Part Sarcoma Pediatric Pathology & Molecular Medicine. 18: 529-543. DOI: 10.1080/15513819809168805  0.45
1997 Li M, Squire JA, Weksberg R. Molecular genetics of Beckwith-Wiedemann syndrome. Current Opinion in Pediatrics. 9: 623-629. PMID 9425596 DOI: 10.1097/00008480-199712000-00012  0.411
1997 Jay V, Squire J, Blaser S, Hoffman HJ, Hwang P. Intracranial and spinal metastases from a ganglioglioma with unusual cytogenetic abnormalities in a patient with complex partial seizures. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 13: 550-5. PMID 9403205 DOI: 10.1007/S003810050136  0.332
1997 Pandita A, Godbout R, Zielenska M, Thorner P, Bayani J, Squire JA. Relational mapping of MYCN and DDXI in band 2p24 and analysis of amplicon arrays in double minute chromosomes and homogeneously staining regions by use of free chromatin FISH. Genes, Chromosomes & Cancer. 20: 243-52. PMID 9365831 DOI: 10.1002/(Sici)1098-2264(199711)20:3<243::Aid-Gcc4>3.0.Co;2-2  0.43
1997 Godbout R, Pandita A, Beatty B, Bie W, Squire JA. Comparative genomic hybridization analysis of Y79 and FISH mapping indicate the amplified human mitochondrial ATP synthase alpha-subunit gene (ATP5A) maps to chromosome 18q12-->q21. Cytogenetics and Cell Genetics. 77: 253-6. PMID 9284928 DOI: 10.1159/000134588  0.434
1997 Wu H, Squire JA, Catzavelos CG, Weksberg R. Relaxation of Imprinting of Human Insulin-like Growth Factor II Gene,IGF2,in Sporadic Breast Carcinomas☆ Biochemical and Biophysical Research Communications. 235: 123-129. PMID 9196048 DOI: 10.1006/Bbrc.1997.6744  0.385
1997 Hannigan GE, Bayani J, Weksberg R, Beatty B, Pandita A, Dedhar S, Squire J. Mapping of the gene encoding the integrin-linked kinase, ILK, to human chromosome 11p15.5-p15.4. Genomics. 42: 177-9. PMID 9177792 DOI: 10.1006/Geno.1997.4719  0.392
1997 Wu HK, Weksberg R, Minden MD, Squire JA. Loss of imprinting of human insulin-like growth factor II gene, IGF2, in acute myeloid leukemia. Biochemical and Biophysical Research Communications. 231: 466-72. PMID 9070302 DOI: 10.1006/Bbrc.1997.6127  0.382
1997 Pienkowska M, Dimitroulakos J, Zielenska M, Thorner P, Plavsic N, Yeger H, Squire JA. Selection of probes for fluorescence in situ hybridization analysis by differential display polymerase chain reaction of mRNA from rhabdomyosarcoma Cancer Genetics and Cytogenetics. 92: 58-65. PMID 8956874 DOI: 10.1016/S0165-4608(96)00132-X  0.415
1997 Lorenzana AN, Zielenska M, Thorner P, Gerrie B, Weitzman S, Squire J. Heterogeneity of MYCN amplification in a child with stroma-rich neuroblastoma (ganglioneuroblastoma). Pediatric Pathology & Laboratory Medicine. 17: 875-883. DOI: 10.1080/15513819709168751  0.418
1996 Squire Ja, McPherson JP, Beatty BG, Goldenberg GJ. Allelic fusion of DNA topoisomerase IIα and retinoic acid receptor α genes in Adriamycin-resistant p388 murine leukemia revealed by fluorescence in situ hybridization Cytogenetic and Genome Research. 75: 164-166. PMID 9040785 DOI: 10.1159/000134470  0.35
1996 Weksberg R, Squire JA. Molecular biology of Beckwith-Wiedemann syndrome Medical and Pediatric Oncology. 27: 462-469. PMID 8827075 DOI: 10.1002/(Sici)1096-911X(199611)27:5<462::Aid-Mpo13>3.0.Co;2-C  0.414
1996 Squire J, Weksberg R. Genomic imprinting in tumours Seminars in Cancer Biology. 7: 41-47. PMID 8695766 DOI: 10.1006/Scbi.1996.0006  0.449
1996 Sheer D, Squire J. Clinical applications of genetic rearrangements in cancer. Seminars in Cancer Biology. 7: 25-32. PMID 8695763 DOI: 10.1006/Scbi.1996.0004  0.33
1996 Squire J, Thorner P, Marrano P, Parkinson D, Ng Y, Gerrie B, Chilton-Macneill S, Zielenska M. Identification of MYCN Copy Number Heterogeneity by Direct FISH Analysis of Neuroblastoma Preparations. Molecular Diagnosis. 1: 281-289. DOI: 10.1016/S1084-8592(96)70010-3  0.419
1996 Sheer D, Squire J. Introduction: Genetic rearrangements in cancer Seminars in Cancer Biology. 7: 1. DOI: 10.1006/Scbi.1996.0001  0.302
1995 Bayani J, Thorner P, Zielenska M, Pandita A, Beatty B, Squire JA. Application of a Simplified Comparative Genomic Hybridization Technique to Screen for Gene Amplification in Pediatric Solid Tumors Pediatric Pathology & Laboratory Medicine. 15: 831-844. PMID 8705194 DOI: 10.3109/15513819509027020  0.422
1995 Jay V, Squire J, Zielenska M, Gerrie B, Humphreys R. Molecular and cytogenetic analysis of a cerebellar primitive neuroectodermal tumor with prominent neuronal differentiation: detection of MYCN amplification by differential polymerase chain reaction and Southern blot analysis. Pediatric Pathology & Laboratory Medicine : Journal of the Society For Pediatric Pathology, Affiliated With the International Paediatric Pathology Association. 15: 733-44. PMID 8597859 DOI: 10.3109/15513819509027009  0.367
1995 Bie W, Squire JA, Fraser M, Paterson MC, Godbout R. Mitochondrial ATP synthase alpha-subunit gene amplified in a retinoblastoma cell line maps to chromosome 18. Genes, Chromosomes & Cancer. 14: 63-7. PMID 8527386 DOI: 10.1002/Gcc.2870140111  0.386
1995 Tay A, Simon JS, Squire J, Hamel K, Jacob HJ, Skorecki K. Cytosolic phospholipase A2 gene in human and rat: chromosomal localization and polymorphic markers. Genomics. 26: 138-41. PMID 7782073 DOI: 10.1016/0888-7543(95)80093-2  0.379
1995 Tan J, D'Agostaro AF, Bendiak B, Reck F, Sarkar M, Squire JA, Leong P, Schachter H. The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein. European Journal of Biochemistry / Febs. 231: 317-28. PMID 7635144 DOI: 10.1111/J.1432-1033.1995.Tb20703.X  0.329
1995 Tan J, D'agostaro GAF, Bendiak B, Reck F, Sarkar M, Squire JA, Leong P, Schachter H. The human UDP‐N‐Acetylglucosamine:α‐6‐d‐Mannoside‐β‐1,2‐N‐Acetylglucosaminyltransferase II Gene (MGAT2) Febs Journal. 231: 317-328. DOI: 10.1111/J.1432-1033.1995.0317E.X  0.314
1994 Jay V, Squire J, Becker LE, Humphreys R. Malignant transformation in a ganglioglioma with anaplastic neuronal and astrocytic components. Report of a case with flow cytometric and cytogenetic analysis. Cancer. 73: 2862-8. PMID 8194028 DOI: 10.1002/1097-0142(19940601)73:11<2862::Aid-Cncr2820731133>3.0.Co;2-5  0.357
1994 Driman D, Thorner PS, Greenberg ML, Chilton-MacNeill S, Squire J. MYCN gene amplification in rhabdomyosarcoma. Cancer. 73: 2231-2237. PMID 8156531 DOI: 10.1002/1097-0142(19940415)73:8<2231::Aid-Cncr2820730832>3.0.Co;2-E  0.41
1994 Jay V, Rutka J, Becker LE, Squire J. Pediatric malignant glioma with tubuloreticular inclusions and MYCN amplification. Report of a case with immunohistochemical, ultrastructural, flow cytometric, karyotypic, and Southern blot analysis. Cancer. 73: 1987-93. PMID 8137227 DOI: 10.1002/1097-0142(19940401)73:7<1987::Aid-Cncr2820730734>3.0.Co;2-J  0.402
1994 Tay A, Squire JA, Goldberg H, Skorecki K. Assignment of the human prostaglandin-endoperoxide synthase 2 (PTGS2) gene to 1q25 by fluorescence in situ hybridization Genomics. 23: 718-719. PMID 7851909 DOI: 10.1006/Geno.1994.1569  0.416
1994 Roux A, Nguyen TTV, Squire JA, Cox DW. A heat shock gene at 14q22: mapping and expression Human Molecular Genetics. 3: 1819-1822. PMID 7849706 DOI: 10.1093/Hmg/3.10.1819  0.386
1994 Salt SNJ, Nowak NJ, Singh‐Kahlon P, Weksberg R, Squire J, Shows TB, Higgins MJ. Localization of Beckwith-Wiedemann and rhabdoid tumor chromosome rearrangements to a defined interval in chromosome band 11p15.5. Genes, Chromosomes and Cancer. 11: 97-105. PMID 7529555 DOI: 10.1002/Gcc.2870110206  0.43
1994 Zipursky A, Wang H, Brown EJ, Squire J. Interphase cytogenetic analysis of in vivo differentiation in the myelodysplasia of Down syndrome Blood. 84: 2278-2282. DOI: 10.1182/Blood.V84.7.2278.2278  0.399
1993 Weksberg R, Teshima I, Williams BRG, Greenberg CR, Pueschel SM, Chernos JE, Fowlow SB, Hoyme E, Anderson IJ, Whiteman DAH, Fisher N, Squire J. Molecular characterization of cytogenetic alterations associated with the Beckwith — Wiedemann syndrome (BWS) phenotype refines the localization and suggests the gene for BWS is imprinted Human Molecular Genetics. 2: 549-556. PMID 8518793 DOI: 10.1093/Hmg/2.5.549  0.419
1993 Godbout R, Squire J. Amplification of a DEAD box protein gene in retinoblastoma cell lines. Proceedings of the National Academy of Sciences of the United States of America. 90: 7578-82. PMID 7689221 DOI: 10.1073/Pnas.90.16.7578  0.339
1993 Squire J, Meurs EF, Chong KL, McMillan NA, Hovanessian AG, Williams BR. Localization of the human interferon-induced, ds-RNA activated p68 kinase gene (PRKR) to chromosome 2p21-p22. Genomics. 16: 768-70. PMID 7686884 DOI: 10.1006/Geno.1993.1263  0.369
1993 Squire J, Zielenska M, Thorner P, Tennyson S, Weitzman S, Pai KM, Yeger H, Ng YK, Weksberg R. Variant translocations of chromosome 22 in Ewing's sarcoma. Genes, Chromosomes & Cancer. 8: 190-4. PMID 7509628 DOI: 10.1002/Gcc.2870080309  0.424
1993 Squire J, Jay V, Becker L, Rutka J. Mycn Amplification And Tubuloreticular Inclusions In A Pediatric Malignant Glioma: An Immunohistochemical, Ultrastructural, Flow Cytometric, Cytogenetic And Southern Blot Analysis Journal of Neuropathology and Experimental Neurology. 52: 322. DOI: 10.1097/00005072-199305000-00249  0.302
1992 Zhu X, Dunn JM, Goddard AD, Squire JA, Becker A, Phillips RA, Gallie BL. Mechanisms of loss of heterozygosity in retinoblastoma. Cytogenetics and Cell Genetics. 59: 248-52. PMID 1544317 DOI: 10.1159/000133261  0.4
1992 Cullinane C, Thorner PS, Greenberg ML, Ng YK, Kumar M, Squire J. Molecular genetic, cytogenetic, and immunohistochemical characterization of alveolar soft-part sarcoma. Implications for cell of origin. Cancer. 70: 2444-2450. PMID 1423174 DOI: 10.1002/1097-0142(19921115)70:10<2444::Aid-Cncr2820701010>3.0.Co;2-6  0.431
1992 Heng HH, Squire J, Tsui LC. High-resolution mapping of mammalian genes by in situ hybridization to free chromatin. Proceedings of the National Academy of Sciences of the United States of America. 89: 9509-13. PMID 1384055 DOI: 10.1073/Pnas.89.20.9509  0.364
1988 Goddard AD, Balakier H, Canton M, Dunn J, Squire J, Reyes E, Becker A, Phillips RA, Gallie BL. Infrequent genomic rearrangement and normal expression of the putative RB1 gene in retinoblastoma tumors. Molecular and Cellular Biology. 8: 2082-8. PMID 2898730 DOI: 10.1128/Mcb.8.5.2082  0.374
1987 Duncan AM, Morgan C, Gallie Bl, Phillips RA, Squire J. Re-evaluation of the sublocalization of esterase D and its relation to the retinoblastoma locus by in situ hybridization. Cytogenetics and Cell Genetics. 44: 153-7. PMID 3032521 DOI: 10.1159/000132361  0.416
1986 Squire J, Dryja TP, Dunn J, Goddard A, Hofmann T, Musarella M, Willard HF, Becker AJ, Gallie BL, Phillips RA. Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13 Proceedings of the National Academy of Sciences of the United States of America. 83: 6573-6577. PMID 3462714 DOI: 10.1073/Pnas.83.17.6573  0.425
1986 Squire J, Goddard AD, Canton M, Becker A, Phillips RA, Gallie BL. Tumour induction by the retinoblastoma mutation is independent of N-myc expression. Nature. 322: 555-7. PMID 2426601 DOI: 10.1038/322555A0  0.325
1985 Squire J, Gallie BL, Phillips RA. A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma. Human Genetics. 70: 291-301. PMID 4018796 DOI: 10.1007/Bf00295364  0.476
1985 Cavenee WK, Hansen MF, Nordenskjold M, Kock E, Maumenee I, Squire JA, Phillips RA, Gallie BL. Genetic origin of mutations predisposing to retinoblastoma. Science (New York, N.Y.). 228: 501-3. PMID 3983638 DOI: 10.1126/Science.3983638  0.439
1984 Squire J, Phillips RA, Boyce S, Godbout R, Rogers B, Gallie BL. Isochromosome 6p, a unique chromosomal abnormality in retinoblastoma: verification by standard staining techniques, new densitometric methods, and somatic cell hybridization. Human Genetics. 66: 46-53. PMID 6583158 DOI: 10.1007/Bf00275185  0.458
1983 Godbout R, Dryja TP, Squire J, Gallie BL, Phillips RA. Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma. Nature. 304: 451-3. PMID 6877367 DOI: 10.1038/304451A0  0.411
1982 Squire JA, Nauth L, Ridler MA, Sutton S, Timberlake C. Prenatal diagnosis and outcome of pregnancy in 2036 women investigated by amniocentesis. Human Genetics. 61: 215-22. PMID 7173865 DOI: 10.1007/Bf00296445  0.307
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