Ming You - Publications

Affiliations: 
Medical College of Ohio, Toledo, OH, United States 
Area:
Genetics, Molecular Biology, Pathology

262 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Li C, Wang Y, Gao S, Hu M, You M. The Chemoprevention Effects of Two Herbal Mixtures on Chemically Induced Lung Tumorigenesis in Mice. Pharmaceuticals (Basel, Switzerland). 16. PMID 38139793 DOI: 10.3390/ph16121666  0.39
2023 Zhang Q, Chen X, Palen K, Johnson B, Bui D, Xiong D, Pan J, Hu M, Wang Y, You M. Cancer chemoprevention with PV-1, a novel -containing herbal mixture that remodels the tumor immune microenvironment in mice. Frontiers in Immunology. 14: 1196434. PMID 38077406 DOI: 10.3389/fimmu.2023.1196434  0.369
2023 Xiong J, Yuan H, Fei S, Yang S, You M, Liu L. The preventive role of the red gingeng ginsenoside Rg3 in the treatment of lung tumorigenesis induced by benzo(a)pyrene. Scientific Reports. 13: 4528. PMID 36941308 DOI: 10.1038/s41598-023-31710-9  0.304
2022 Huang M, Xiong D, Pan J, Zhang Q, Sei S, Shoemaker RH, Lubet RA, Montuenga LM, Wang Y, Slusher BS, You M. Targeting Glutamine Metabolism to Enhance Immunoprevention of EGFR-Driven Lung Cancer. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2105885. PMID 35861366 DOI: 10.1002/advs.202105885  0.361
2022 Zhang Q, Xiong D, Pan J, Wang Y, Hardy M, Kalyanaraman B, You M. Chemoprevention of Lung Cancer with a Combination of Mitochondria-Targeted Compounds. Cancers. 14. PMID 35626143 DOI: 10.3390/cancers14102538  0.354
2021 Zhang Q, Pan J, Xiong D, Wang Y, Miller MS, Sei S, Shoemaker RH, Izzotti A, You M. Pulmonary Aerosol Delivery of Let-7b microRNA Confers a Striking Inhibitory Effect on Lung Carcinogenesis through Targeting the Tumor Immune Microenvironment. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2100629. PMID 34236760 DOI: 10.1002/advs.202100629  0.303
2020 Zhang Q, Cheng G, Pan J, Zielonka J, Xiong D, Myers CR, Feng L, Shin SS, Kim YH, Bui D, Hu M, Bennett B, Schmainda K, Wang Y, Kalyanaraman B, ... You M, et al. Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I. Cell Communication and Signaling : Ccs. 18: 58. PMID 32264893 DOI: 10.1186/S12964-020-0524-2  0.323
2020 Pan J, Zhang Q, Palen K, Johnson B, Wang L, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M. Abstract 4584: A novel combination of a multipeptide KRAS vaccine and an ACAT1 inhibitor to prevent lung cancer Immunology. 80: 4584-4584. DOI: 10.1158/1538-7445.Am2020-4584  0.476
2020 Musolf AM, Simpson CL, Moiz BA, Andrade Md, Mandal D, Gaba C, Yang P, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE. Abstract 37: Highly aggregated lung cancer families reveal a heterogeneous cause for a previous linkage signal on 6q Epidemiology. 80: 37-37. DOI: 10.1158/1538-7445.Am2020-37  0.392
2019 Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, ... ... You M, et al. miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer. Cell Reports. 29: 4389-4406.e10. PMID 31875548 DOI: 10.1016/J.Celrep.2019.11.085  0.353
2019 Cheng G, Pan J, Podsiadly R, Zielonka J, Garces AM, Dias Duarte Machado LG, Bennett B, McAllister D, Dwinell MB, You M, Kalyanaraman B. Increased formation of reactive oxygen species during tumor growth: Ex vivo low-temperature EPR and in vivo bioluminescence analyses. Free Radical Biology & Medicine. PMID 31874251 DOI: 10.1016/J.Freeradbiomed.2019.12.020  0.36
2019 Musolf AM, Moiz BA, Sun H, Pikielny CW, Bossé Y, Mandal D, de Andrade M, Gaba C, Yang P, Li Y, You M, Govindan R, Wilson RK, Kupert EY, Anderson MW, et al. Whole Exome Sequencing of Highly Aggregated Lung Cancer Families Reveals Linked Loci for Increased Cancer Risk on Chromosomes 12q, 7p and 4q. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 31826912 DOI: 10.1158/1055-9965.Epi-19-0887  0.399
2019 Pan J, Zhang Q, Palen K, Wang L, Qiao L, Johnson B, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M. Potentiation of Kras peptide cancer vaccine by avasimibe, a cholesterol modulator. Ebiomedicine. PMID 31680003 DOI: 10.1016/J.Ebiom.2019.10.044  0.362
2019 Xiong D, Wang Y, You M. Tumor intrinsic immunity related proteins may be novel tumor suppressors in some types of cancer. Scientific Reports. 9: 10918. PMID 31358815 DOI: 10.1038/S41598-019-47382-3  0.434
2019 Cheng G, Zhang Q, Pan J, Lee Y, Ouari O, Hardy M, Zielonka M, Myers CR, Zielonka J, Weh K, Chang AC, Chen G, Kresty L, Kalyanaraman B, You M. Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis. Nature Communications. 10: 2205. PMID 31101821 DOI: 10.1038/S41467-019-10042-1  0.448
2019 Zhou Y, Zhang Q, Du M, Xiong D, Wang Y, Mohammed A, Lubet RA, Wang L, You M. Exosomal miRNAs as Novel Pharmacodynamic Biomarkers for Cancer Chemopreventive Agent Early Stage Treatments in Chemically Induced Mouse Model of Lung Squamous Cell Carcinoma. Cancers. 11. PMID 30987362 DOI: 10.3390/Cancers11040477  0.42
2019 Zhang Q, Lee SB, Chen X, Stevenson M, Pan J, Xiong D, Zhou Y, Miller M, Lubet RA, Wang Y, Mirza S, You M. Optimized bexarotene aerosol formulation inhibits major subtypes of lung cancer in mice. Nano Letters. PMID 30873838 DOI: 10.1021/Acs.Nanolett.8B04309  0.464
2019 Zhou Y, You M. Integrative system genetic analysis reveals mRNA-lncRNA network associated with mouse spontaneous lung cancer susceptibility. Oncotarget. 10: 339-351. PMID 30719228 DOI: 10.18632/Oncotarget.26554  0.425
2019 Musolf A, Sun H, Moiz BA, Pikielny CW, Andrade Md, Mandal D, Gaba C, Yang P, Li Y, You M, Wilson RK, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, et al. Abstract 4176: Familial lung cancer exhibits multiple novel linked haplotypes within pedigrees Cancer Research. 79: 4176-4176. DOI: 10.1158/1538-7445.Sabcs18-4176  0.38
2019 Pikielny CW, Musolf AM, Andrade Md, Mandal D, Gaba C, Yang P, Li y, You M, Wilson R, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Granizo-Mackenzie AI, Liu Y, et al. Abstract LB-053: Familial studies identify variants in the E2A transcription factor as putative risk factors for lung cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-053  0.385
2018 Xiong D, Wang Y, Singavi AK, Mackinnon AC, George B, You M. Immunogenomic Landscape Contributes to Hyperprogressive Disease after Anti-PD-1 Immunotherapy for Cancer. Iscience. 9: 258-277. PMID 30439581 DOI: 10.1016/J.Isci.2018.10.021  0.378
2018 Pan J, Lee Y, Cheng G, Zielonka J, Zhang Q, Bajzikova M, Xiong D, Tsaih SW, Hardy M, Flister M, Olsen CM, Wang Y, Vang O, Neuzil J, Myers CR, ... ... You M, et al. Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity. Iscience. 3: 192-207. PMID 30428319 DOI: 10.1016/J.Isci.2018.04.013  0.428
2018 Liu Y, Lusk CM, Cho MH, Silverman EK, Qiao D, Zhang R, Scheurer ME, Kheradmand F, Wheeler DA, Tsavachidis S, Armstrong G, Zhu D, Wistuba II, Chow CB, Behrens C, ... ... You M, et al. Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 29981437 DOI: 10.1016/J.Jtho.2018.06.016  0.383
2018 Byun J, Schwartz AG, Lusk C, Wenzlaff AS, de Andrade M, Mandal D, Gaba C, Yang P, You M, Kupert EY, Anderson MW, Han Y, Li Y, Qian D, Stilp A, et al. Genome-Wide Association Study of Familial Lung Cancer. Carcinogenesis. PMID 29924316 DOI: 10.1093/Carcin/Bgy080  0.428
2018 Pan J, Xiong D, Zhang Q, Szabo E, Miller MS, Lubet RA, Wang Y, You M. Airway brushing as a new experimental methodology to detect airway gene expression signatures in mouse lung squamous cell carcinoma. Scientific Reports. 8: 8895. PMID 29891994 DOI: 10.1038/S41598-018-26902-7  0.467
2018 Xiong D, Pan J, Yin Y, Jiang H, Szabo E, Lubet RA, Wang Y, You M. Novel mutational landscapes and expression signatures of lung squamous cell carcinoma. Oncotarget. 9: 7424-7441. PMID 29484121 DOI: 10.18632/Oncotarget.23716  0.521
2017 Pan J, Zhang Q, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M. Immunoprevention of KRAS-driven lung adenocarcinoma by a multipeptide vaccine. Oncotarget. 8: 82689-82699. PMID 29137294 DOI: 10.18632/Oncotarget.19831  0.333
2017 Zhang Q, Li R, Chen X, Lee SB, Pan J, Xiong D, Hu J, Miller MS, Szabo E, Lubet RA, Wang Y, You M. Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer. Oncotarget. 8: 72447-72456. PMID 29069801 DOI: 10.18632/Oncotarget.19785  0.377
2017 Musolf AM, Simpson CL, de Andrade M, Mandal D, Gaba C, Yang P, Li Y, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE. Parametric Linkage Analysis Identifies Five Novel Genome-Wide Significant Loci for Familial Lung Cancer. Human Heredity. 82: 64-74. PMID 28817824 DOI: 10.1159/000479028  0.406
2017 Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, Wang Y, You M. Pioglitazone-mediated reversal of elevated glucose metabolism in the airway epithelium of mouse lung adenocarcinomas. Jci Insight. 2. PMID 28679956 DOI: 10.1172/Jci.Insight.94220  0.449
2017 Lieberman R, Pan J, Zhang Q, You M. Rad52 deficiency decreases development of lung squamous cell carcinomas by enhancing immuno-surveillance. Oncotarget. PMID 28415565 DOI: 10.18632/Oncotarget.16371  0.379
2017 Musolf AM, Simpson CL, de Andrade M, Mandal D, Gaba C, Yang P, Li Y, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE. Familial Lung Cancer: A Brief History from the Earliest Work to the Most Recent Studies. Genes. 8. PMID 28106732 DOI: 10.3390/Genes8010036  0.42
2017 Musolf AM, Simpson CL, Moiz BA, Middlebrooks C, Andrade Md, Mandal D, Gaba C, Yang P, Li Y, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, et al. Abstract 4290: A study in locus heterogeneity: Targeted sequencing analysis of 6q reveals multiple significant loci as the source of a previous linkage peak in familial lung cancer Epidemiology. 77: 4290-4290. DOI: 10.1158/1538-7445.Am2017-4290  0.373
2017 Bailey-Wilson JE, Musolf AM, Simpson CL, Andrade Md, Mandal D, Gaba CG, Yang P, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI. Abstract 4268: Familial lung cancer is significantly linked to cancer-associated genes on five chromosomes Cancer Research. 77: 4268-4268. DOI: 10.1158/1538-7445.Am2017-4268  0.423
2017 Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, You M, Wang Y. Abstract 2423: Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents Cancer Research. 77: 2423-2423. DOI: 10.1158/1538-7445.Am2017-2423  0.445
2017 Zhang Q, Pan J, Miller MS, Lubet RA, Wang Y, You M. Abstract 188: Preventive effect of aerosolized bexarotene in three major subtypes of lung cancer: adenocarcinoma, squamous cell carcinoma and small cell lung cancer in mice Cancer Research. 77: 188-188. DOI: 10.1158/1538-7445.Am2017-188  0.494
2017 Pan J, Zhang Q, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M. Abstract 1698: Immunoprevention of KRAS-driven lung adenocarcinoma by a multi-peptide KRAS vaccine Cancer Research. 77: 1698-1698. DOI: 10.1158/1538-7445.Am2017-1698  0.396
2016 Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, You M, Wang Y. Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. Oncotarget. PMID 27935865 DOI: 10.18632/Oncotarget.13806  0.486
2016 Pan J, Lee Y, Zhang Q, Xiong D, Tina WC, Wang Y, You M. Honokiol Decreases Lung Cancer Metastasis through Inhibition of the STAT3 Signaling Pathway. Cancer Prevention Research (Philadelphia, Pa.). PMID 27849557 DOI: 10.1158/1940-6207.Capr-16-0129  0.461
2016 Liu D, You M, Xu Y, Li F, Zhang D, Li X, Hou Y. Inhibition of curcumin on myeloid-derived suppressor cells is requisite for controlling lung cancer. International Immunopharmacology. 39: 265-272. PMID 27497194 DOI: 10.1016/j.intimp.2016.07.035  0.392
2016 Ebben JD, You M. Brain Metastasis in Lung Cancer: Building a Molecular and Systems-Level Understanding to Improve Outcomes. The International Journal of Biochemistry & Cell Biology. PMID 27474492 DOI: 10.1016/J.Biocel.2016.07.025  0.397
2016 Pan J, Lee Y, Wang Y, You M. Honokiol targets mitochondria to halt cancer progression and metastasis. Molecular Nutrition & Food Research. 60: 1383-1395. PMID 27276215 DOI: 10.1002/Mnfr.201501007  0.352
2016 Liu Y, Kheradmand F, Davis CF, Scheurer ME, Wheeler D, Tsavachidis S, Armstrong G, Simpson C, Mandal D, Kupert E, Anderson M, You M, Xiong D, Pikielny C, Schwartz AG, et al. Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 11: 52-61. PMID 26762739 DOI: 10.1016/J.Jtho.2015.09.015  0.354
2016 Lieberman R, Xiong D, You M. Abstract 4172: A role for RAD52 as a lung cancer susceptibility gene in the 12p13.33 locus Cancer Research. 76: 4172-4172. DOI: 10.1158/1538-7445.Am2016-4172  0.455
2016 Lee Y, Pan J, Zhang Q, Wang Y, You M. Abstract 4118: Honokiol inhibits lung cancer brain metastasis through inhibition of STAT3 signaling pathway Cancer Research. 76: 4118-4118. DOI: 10.1158/1538-7445.Am2016-4118  0.453
2016 Musolf AM, Simpson CL, Andrade Md, Mandal D, Gaba C, Yang P, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE. Abstract 2542: Chromatin remodeling gene ARID1B is linked to familial lung cancer Cancer Research. 76: 2542-2542. DOI: 10.1158/1538-7445.Am2016-2542  0.398
2015 Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, ... ... You M, et al. Patterns and functional implications of rare germline variants across 12 cancer types. Nature Communications. 6: 10086. PMID 26689913 DOI: 10.1038/Ncomms10086  0.351
2015 Liu JM, You M, Wang Z, Li GZ, Xu X, Qiu Z. Cough event classification by pretrained deep neural network. Bmc Medical Informatics and Decision Making. 15: S2. PMID 26606168 DOI: 10.1186/1472-6947-15-S4-S2  0.647
2015 Ebben JD, Lubet RA, Gad E, Disis ML, You M. Epidermal growth factor receptor derived peptide vaccination to prevent lung adenocarcinoma formation: An in vivo study in a murine model of EGFR mutant lung cancer. Molecular Carcinogenesis. PMID 26346412 DOI: 10.1002/Mc.22405  0.37
2015 Xiong D, Wang Y, You M. PARK2 gene and familial lung cancer: what is the link? Future Oncology (London, England). 11: 1707-10. PMID 26075437 DOI: 10.2217/Fon.15.79  0.423
2015 Lee Y, Wang Y, James M, Jeong JH, You M. Inhibition of IGF1R signaling abrogates resistance to afatinib (BIBW2992) in EGFR T790M mutant lung cancer cells. Molecular Carcinogenesis. PMID 26052929 DOI: 10.1002/Mc.22342  0.389
2015 Lieberman R, Xiong D, James M, Han Y, Amos CI, Wang L, You M. Functional characterization of RAD52 as a lung cancer susceptibility gene in the 12p13.33 locus. Molecular Carcinogenesis. PMID 26013599 DOI: 10.1002/Mc.22334  0.45
2015 Zhang Q, Pan J, Lubet RA, Komas SM, Kalyanaraman B, Wang Y, You M. Enhanced antitumor activity of 3-bromopyruvate in combination with rapamycin in vivo and in vitro. Cancer Prevention Research (Philadelphia, Pa.). 8: 318-26. PMID 25644152 DOI: 10.1158/1940-6207.Capr-14-0142  0.48
2015 Xiong D, Wang Y, Kupert E, Simpson C, Pinney SM, Gaba CR, Mandal D, Schwartz AG, Yang P, de Andrade M, Pikielny C, Byun J, Li Y, Stambolian D, Spitz MR, ... ... You M, et al. A recurrent mutation in PARK2 is associated with familial lung cancer. American Journal of Human Genetics. 96: 301-8. PMID 25640678 DOI: 10.1016/J.Ajhg.2014.12.016  0.437
2015 Zhang Q, Pan J, Lubet RA, Wang Y, You M. Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention. Molecular Carcinogenesis. 54: E129-37. PMID 25163779 DOI: 10.1002/Mc.22206  0.501
2015 Toledo DM, Pinney SM, Mandal D, Andrade Md, Kupert E, Franks J, Gaba C, Simpson CL, You M, Anderson MW, Bailey-Wilson JE, Amos CI, Schwartz A. Abstract LB-189: Genetic Epidemiology of Lung Cancer Consortium: genome-wide association study of familial lung cancer cases: Epidemiology. 75. DOI: 10.1158/1538-7445.Am2015-Lb-189  0.406
2015 Liu Y, Kheradmand F, Scheurer M, Davis C, Wheeler D, Silverman E, Sanjay S, Tsavachidis S, Armstrong G, Kupert E, Anderson M, Li Y, Pikielny C, Bailey-Wilson JE, You M, et al. Abstract 4600: Target exome sequencing for disease-causing rare mutations in familial and sporadic lung cancer Cancer Research. 75: 4600-4600. DOI: 10.1158/1538-7445.Am2015-4600  0.351
2015 Bailey-Wilson JE, Simpson CL, Pinney SM, Andrade Md, Gaba C, Yang P, You M, Kupert EY, Schwartz AG, Mandal D, Amos CI, Anderson MW. Abstract 2757: Evaluation ofEYA4as a candidate risk locus in familial lung cancer families linked to 6q Cancer Research. 75: 2757-2757. DOI: 10.1158/1538-7445.Am2015-2757  0.321
2015 Huang M, Wang Y, Xu L, You M. Anti-tumor Properties of Prunella vulgaris Current Pharmacology Reports. 1: 401-419. DOI: 10.1007/S40495-015-0038-6  0.37
2015 Jiao L, Wang Y, Xu L, You M. Lung Cancer Prevention and Therapy Using the JinFuKang Herbal Mixture Current Pharmacology Reports. 1: 346-353. DOI: 10.1007/S40495-015-0037-7  0.434
2014 Pan J, Zhang Q, Liu Q, Komas SM, Kalyanaraman B, Lubet RA, Wang Y, You M. Honokiol inhibits lung tumorigenesis through inhibition of mitochondrial function. Cancer Prevention Research (Philadelphia, Pa.). 7: 1149-59. PMID 25245764 DOI: 10.1158/1940-6207.Capr-14-0091  0.443
2014 Sun Z, Wang L, Eckloff BW, Deng B, Wang Y, Wampfler JA, Jang J, Wieben ED, Jen J, You M, Yang P. Conserved recurrent gene mutations correlate with pathway deregulation and clinical outcomes of lung adenocarcinoma in never-smokers. Bmc Medical Genomics. 7: 32. PMID 24894543 DOI: 10.1186/1755-8794-7-32  0.417
2014 Morrison CD, Liu P, Woloszynska-Read A, Zhang J, Luo W, Qin M, Bshara W, Conroy JM, Sabatini L, Vedell P, Xiong D, Liu S, Wang J, Shen H, Li Y, ... ... You M, et al. Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: E672-81. PMID 24469795 DOI: 10.1073/Pnas.1313580111  0.407
2014 James MA, Vikis HG, Tate E, Rymaszewski AL, You M. CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis. Cancer Research. 74: 1116-27. PMID 24366883 DOI: 10.1158/0008-5472.Can-13-1617  0.487
2014 Nicastro HL, Grubbs CJ, Margaret Juliana M, Bode AM, Kim MS, Lu Y, You M, Milne GL, Boring D, Steele VE, Lubet RA. Preventive effects of NSAIDs, NO-NSAIDs, and NSAIDs plus difluoromethylornithine in a chemically induced urinary bladder cancer model. Cancer Prevention Research (Philadelphia, Pa.). 7: 246-54. PMID 24346344 DOI: 10.1158/1940-6207.Capr-13-0164  0.34
2014 Pan J, Zhang Q, Xiong D, Vedell P, Yan Y, Jiang H, Cui P, Ding F, Tichelaar JW, Wang Y, Lubet RA, You M. Transcriptomic analysis by RNA-seq reveals AP-1 pathway as key regulator that green tea may rely on to inhibit lung tumorigenesis. Molecular Carcinogenesis. 53: 19-29. PMID 24343902 DOI: 10.1002/Mc.21941  0.389
2014 Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, ... ... You M, et al. EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. Oncogene. 33: 4464-73. PMID 24096489 DOI: 10.1038/Onc.2013.396  0.515
2014 Vedell PT, Townsend RR, You M, Malone JP, Grubbs CJ, Bland KI, Muccio DD, Atigadda VR, Chen Y, Vignola K, Lubet RA. Global molecular changes in rat livers treated with RXR agonists: a comparison using transcriptomics and proteomics Pharmacology Research & Perspectives. 2: e00074. DOI: 10.1002/Prp2.74  0.313
2013 Shoghi KI, Xu J, Su Y, He J, Rowland D, Yan Y, Garbow JR, Tu Z, Jones LA, Higashikubo R, Wheeler KT, Lubet RA, Mach RH, You M. Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1. Plos One. 8: e74188. PMID 24073202 DOI: 10.1371/Journal.Pone.0074188  0.367
2013 Lu Y, You M, Ghazoui Z, Liu P, Vedell PT, Wen W, Bode AM, Grubbs CJ, Lubet RA. Concordant effects of aromatase inhibitors on gene expression in ER+ Rat and human mammary cancers and modulation of the proteins coded by these genes. Cancer Prevention Research (Philadelphia, Pa.). 6: 1151-61. PMID 24067424 DOI: 10.1158/1940-6207.Capr-13-0126  0.407
2013 Leikauf GD, Concel VJ, Bein K, Liu P, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA, Upadhyay S, Cario C, Di YP, Vuga LJ, Kostem E, ... ... You M, et al. Functional genomic assessment of phosgene-induced acute lung injury in mice. American Journal of Respiratory Cell and Molecular Biology. 49: 368-83. PMID 23590305 DOI: 10.1165/Rcmb.2012-0337Oc  0.349
2013 Pan J, Zhang Q, Li K, Liu Q, Wang Y, You M. Chemoprevention of lung squamous cell carcinoma by ginseng. Cancer Prevention Research (Philadelphia, Pa.). 6: 530-9. PMID 23550152 DOI: 10.1158/1940-6207.Capr-12-0366  0.487
2013 Vedell PT, Lu Y, Grubbs CJ, Yin Y, Jiang H, Bland KI, Muccio DD, Cvetkovic D, You M, Lubet R. Effects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin (Bexarotene). Molecular Pharmacology. 83: 698-708. PMID 23292798 DOI: 10.1124/Mol.112.082404  0.348
2013 You MS, Rouggly LC, You M, Wang Y. Mouse models of lung squamous cell carcinomas. Cancer Metastasis Reviews. 32: 77-82. PMID 23229817 DOI: 10.1007/S10555-012-9406-4  0.432
2013 Dragnev K, You M, Wang Y, Lubet R. Lung cancer chemoprevention: difficulties, promise and potential agents? Expert Opinion On Investigational Drugs. 22: 35-47. PMID 23167766 DOI: 10.1517/13543784.2013.731392  0.375
2013 Zhang Q, Pan J, Wang Y, Lubet R, You M. Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-induced lung tumorigenesis through apoptosis. Molecular Carcinogenesis. 52: 686-91. PMID 22456940 DOI: 10.1002/Mc.21907  0.51
2013 Wang Y, Yao R, Gao S, Wen W, Du Y, Szabo E, Hu M, Lubet RA, You M. Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis. Molecular Carcinogenesis. 52: 49-56. PMID 22086836 DOI: 10.1002/Mc.20877  0.703
2012 Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, Maher CA, Fulton R, Fulton L, Wallis J, Chen K, Walker J, McDonald S, Bose R, Ornitz D, ... ... You M, et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell. 150: 1121-34. PMID 22980976 DOI: 10.1016/J.Cell.2012.08.024  0.449
2012 Kreisel D, Gelman AE, Higashikubo R, Lin X, Vikis HG, White JM, Toth KA, Deshpande C, Carreno BM, You M, Taffner SM, Yokoyama WM, Bui JD, Schreiber RD, Krupnick AS. Strain-specific variation in murine natural killer gene complex contributes to differences in immunosurveillance for urethane-induced lung cancer. Cancer Research. 72: 4311-7. PMID 22751136 DOI: 10.1158/0008-5472.CAN-12-0908  0.359
2012 Li HH, Li Q, Liu P, Liu Y, Li J, Wasserloos K, Chao W, You M, Oury TD, Chhinder S, Hackam DJ, Billiar TR, Leikauf GD, Pitt BR, Zhang LM. WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury. American Journal of Respiratory Cell and Molecular Biology. 47: 528-35. PMID 22700866 DOI: 10.1165/Rcmb.2012-0127Oc  0.419
2012 Xiong D, Li G, Li K, Xu Q, Pan Z, Ding F, Vedell P, Liu P, Cui P, Hua X, Jiang H, Yin Y, Zhu Z, Li X, Zhang B, ... ... You M, et al. Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients. Carcinogenesis. 33: 1797-805. PMID 22696596 DOI: 10.1093/Carcin/Bgs210  0.475
2012 James MA, Wen W, Wang Y, Byers LA, Heymach JV, Coombes KR, Girard L, Minna J, You M. Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus. Plos One. 7: e36116. PMID 22675468 DOI: 10.1371/Journal.Pone.0036116  0.501
2012 Yang Z, Wang JR, Niu T, Gao S, Yin T, You M, Jiang ZH, Hu M. Inhibition of P-glycoprotein leads to improved oral bioavailability of compound K, an anticancer metabolite of red ginseng extract produced by gut microflora. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1538-44. PMID 22584255 DOI: 10.1124/Dmd.111.044008  0.3
2012 Liu P, Morrison C, Wang L, Xiong D, Vedell P, Cui P, Hua X, Ding F, Lu Y, James M, Ebben JD, Xu H, Adjei AA, Head K, Andrae JW, ... ... You M, et al. Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis. 33: 1270-6. PMID 22510280 DOI: 10.1093/Carcin/Bgs148  0.473
2012 Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA, Upadhyay S, Di YP, Li Q, Hu Z, ... ... You M, et al. Integrative assessment of chlorine-induced acute lung injury in mice. American Journal of Respiratory Cell and Molecular Biology. 47: 234-44. PMID 22447970 DOI: 10.1165/Rcmb.2012-0026Oc  0.413
2012 Zhang Q, Pan J, North PE, Yang S, Lubet RA, Wang Y, You M. Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity. Cancer Prevention Research (Philadelphia, Pa.). 5: 717-25. PMID 22401980 DOI: 10.1158/1940-6207.Capr-11-0338  0.505
2012 Lu Y, Govindan R, Wang L, Liu PY, Goodgame B, Wen W, Sezhiyan A, Pfeifer J, Li YF, Hua X, Wang Y, Yang P, You M. MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. Carcinogenesis. 33: 1046-54. PMID 22331473 DOI: 10.1093/Carcin/Bgs100  0.314
2012 Lu Y, Wang L, Liu P, Yang P, You M. Gene-expression signature predicts postoperative recurrence in stage I non-small cell lung cancer patients. Plos One. 7: e30880. PMID 22292069 DOI: 10.1371/Journal.Pone.0030880  0.399
2012 Krupnick AS, Tidwell VK, Engelbach JA, Alli VV, Nehorai A, You M, Vikis HG, Gelman AE, Kreisel D, Garbow JR. Quantitative monitoring of mouse lung tumors by magnetic resonance imaging. Nature Protocols. 7: 128-42. PMID 22222788 DOI: 10.1038/Nprot.2011.424  0.47
2012 Wang Y, Rouggly L, You M, Lubet R. Animal models of lung cancer characterization and use for chemoprevention research. Progress in Molecular Biology and Translational Science. 105: 211-26. PMID 22137433 DOI: 10.1016/B978-0-12-394596-9.00007-X  0.447
2012 Liu P, Lu Y, Liu H, Wen W, Jia D, Wang Y, You M. Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice. Molecular Cancer Research : McR. 10: 66-74. PMID 22127497 DOI: 10.1158/1541-7786.Mcr-10-0540  0.413
2012 Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M. Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. Molecular Carcinogenesis. 51: 993-1002. PMID 22006501 DOI: 10.1002/Mc.20870  0.49
2012 Lu Y, Liu P, Van den Bergh F, Zellmer V, James M, Wen W, Grubbs CJ, Lubet RA, You M. Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer. Cancer Prevention Research (Philadelphia, Pa.). 5: 248-59. PMID 21982874 DOI: 10.1158/1940-6207.Capr-10-0363  0.463
2012 Amos C, Bailey-Wilson J, Pinney S, Andrada Md, Gaba C, Mandal D, You M, Spitz M, Anderson M. Abstract A106: Optimal strategies for selecting samples for sequencing families with a common cancer: The Genetic Epidemiology of Lung Cancer Consortium. Cancer Prevention Research. 5. DOI: 10.1158/1940-6207.Prev-12-A106  0.371
2012 Lubet R, Vedell P, Grubbs C, Bernard P, You M. Abstract P1-08-02: Gene expression changes in methylnitrosourea (MNU)-induced ER+mammary cancers following short-term treatment of rats with SERMs (Tamoxifen and Arzoxifene) Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P1-08-02  0.396
2011 Liu J, You M, Pu Y, Liu H, Ye M, Tan W. Recent developments in protein and cell-targeted aptamer selection and applications. Current Medicinal Chemistry. 18: 4117-25. PMID 21838693 DOI: 10.2174/092986711797189619  0.661
2011 Yang Z, Gao S, Wang J, Yin T, Teng Y, Wu B, You M, Jiang Z, Hu M. Enhancement of oral bioavailability of 20(S)-ginsenoside Rh2 through improved understanding of its absorption and efflux mechanisms. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1866-72. PMID 21757611 DOI: 10.1124/Dmd.111.040006  0.317
2011 Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, et al. Principles for the post-GWAS functional characterization of cancer risk loci. Nature Genetics. 43: 513-8. PMID 21614091 DOI: 10.1038/Ng.840  0.332
2011 Fu H, Zhang J, Pan J, Zhang Q, Lu Y, Wen W, Lubet RA, Szabo E, Chen R, Wang Y, Chen DR, You M. Chemoprevention of lung carcinogenesis by the combination of aerosolized budesonide and oral pioglitazone in A/J mice. Molecular Carcinogenesis. 50: 913-21. PMID 21374736 DOI: 10.1002/Mc.20751  0.479
2011 Lubet RA, Lu Y, Bode AM, You M, Verney ZM, Steele VE, Townsend R, Juliana MM, Grubbs CJ. Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers. Oncology Reports. 25: 1389-97. PMID 21369704 DOI: 10.3892/Or.2011.1200  0.414
2011 Leikauf GD, Concel VJ, Liu P, Bein K, Berndt A, Ganguly K, Jang AS, Brant KA, Dietsch M, Pope-Varsalona H, Dopico RA, Di YP, Li Q, Vuga LJ, Medvedovic M, ... ... You M, et al. Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1. American Journal of Respiratory and Critical Care Medicine. 183: 1499-509. PMID 21297076 DOI: 10.1164/Rccm.201006-0912Oc  0.372
2011 Zhang Q, Pan J, Zhang J, Liu P, Chen R, Chen DR, Lubet R, Wang Y, You M. Aerosolized bexarotene inhibits lung tumorigenesis without increasing plasma triglyceride and cholesterol levels in mice. Cancer Prevention Research (Philadelphia, Pa.). 4: 270-6. PMID 21163938 DOI: 10.1158/1940-6207.Capr-10-0246  0.486
2011 James MA, Fu H, Liu Y, Chen DR, You M. Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis. Molecular Carcinogenesis. 50: 1-7. PMID 21061266 DOI: 10.1002/Mc.20690  0.467
2011 Lu Y, Liu P, Grubbs C, Lubet R, You M. Abstract 818: Modulation of gene expression and cell cycle signaling pathways in Iressa-treated urinary bladder cancer in rats Cancer Research. 71: 818-818. DOI: 10.1158/1538-7445.Am2011-818  0.457
2011 Townsend RR, Rohrs H, LeDuc R, Malone JP, Erdman-Gilmore P, Hill DL, Grubbs CJ, You M, Lubet RA. Abstract 3700: Proteomic credentialing in a model for chemoprevention studies of urinary bladder cancer Cancer Research. 71: 3700-3700. DOI: 10.1158/1538-7445.Am2011-3700  0.398
2011 Wang Y, James M, Wen W, Lu Y, Szabo E, Lubet RA, You M. Abstract 3698: Chemopreventive efficacy of pioglitazone on lung cancer in mice Cancer Research. 71: 3698-3698. DOI: 10.1158/1538-7445.Am2011-3698  0.503
2011 Grubbs CJ, Boring D, Steele VE, Verney ZM, Lu Y, You M, Lubet RA. Abstract 1849: Chemopreventive efficacy of naproxen, sulindac, and their nitric oxide-derivatives in the hydroxylbutyl(butyl)nitrosamine induced model of urinary bladder cancer Cancer Research. 71: 1849-1849. DOI: 10.1158/1538-7445.Am2011-1849  0.353
2011 Lubet R, Grubbs C, Bode A, You M, Lu Y. P3-10-02: Gene Expression Changes in Methylnitrosourea (MNU)-Induced ER+ Mammary Cancers Following Short-Term Treatment of Rats with the Aromatase Inhibitor Vorozole. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P3-10-02  0.359
2010 Lu Y, Liu P, Wen W, Grubbs CJ, Townsend RR, Malone JP, Lubet RA, You M. Cross-species comparison of orthologous gene expression in human bladder cancer and carcinogen-induced rodent models. American Journal of Translational Research. 3: 8-27. PMID 21139803  0.338
2010 Wang Y, James M, Wen W, Lu Y, Szabo E, Lubet RA, You M. Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice. Molecular Cancer Therapeutics. 9: 3074-82. PMID 21045137 DOI: 10.1158/1535-7163.Mct-10-0510  0.49
2010 Fang S, Pinney SM, Bailey-Wilson JE, de Andrade MA, Li Y, Kupert E, You M, Schwartz AG, Yang P, Anderson MW, Amos CI. Ordered subset analysis identifies loci influencing lung cancer risk on chromosomes 6q and 12q. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 3157-66. PMID 21030603 DOI: 10.1158/1055-9965.Epi-10-0792  0.363
2010 Pan J, Zhang Q, Wang Y, You M. 26S proteasome activity is down-regulated in lung cancer stem-like cells propagated in vitro. Plos One. 5: e13298. PMID 20949018 DOI: 10.1371/Journal.Pone.0013298  0.475
2010 Tichelaar JW, Yan Y, Tan Q, Wang Y, Estensen RD, Young MR, Colburn NH, Yin H, Goodin C, Anderson MW, You M. A dominant-negative c-jun mutant inhibits lung carcinogenesis in mice. Cancer Prevention Research (Philadelphia, Pa.). 3: 1148-56. PMID 20716630 DOI: 10.1158/1940-6207.Capr-10-0023  0.501
2010 Vikis HG, Jackson EN, Krupnick AS, Franklin A, Gelman AE, Chen Q, Piwnica-Worms D, You M. Strain-specific susceptibility for pulmonary metastasis of sarcoma 180 cells in inbred mice. Cancer Research. 70: 4859-67. PMID 20501835 DOI: 10.1158/0008-5472.Can-09-4177  0.36
2010 Liu P, Yang P, Wu X, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, ... ... You M, et al. A second genetic variant on chromosome 15q24-25.1 associates with lung cancer. Cancer Research. 70: 3128-35. PMID 20395203 DOI: 10.1158/0008-5472.Can-09-3583  0.382
2010 Amos CI, Pinney SM, Li Y, Kupert E, Lee J, de Andrade MA, Yang P, Schwartz AG, Fain PR, Gazdar A, Minna J, Wiest JS, Zeng D, Rothschild H, Mandal D, ... You M, et al. A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers. Cancer Research. 70: 2359-67. PMID 20215501 DOI: 10.1158/0008-5472.Can-09-3096  0.342
2010 Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, ... ... You M, et al. Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 517-24. PMID 20142248 DOI: 10.1158/1055-9965.Epi-09-0791  0.401
2010 Zhang Q, Fu H, Pan J, He J, Ryota S, Hara Y, Wang Y, Lubet RA, You M. Effect of dietary Polyphenon E and EGCG on lung tumorigenesis in A/J Mice. Pharmaceutical Research. 27: 1066-71. PMID 20112129 DOI: 10.1007/S11095-010-0056-3  0.385
2010 Dwyer-Nield LD, McQuillan J, Hill-Baskin A, Radcliffe RA, You M, Nadeau JH, Malkinson AM. Epistatic interactions govern chemically-induced lung tumor susceptibility and Kras mutation site in murine C57BL/6J-ChrA/J chromosome substitution strains. International Journal of Cancer. 126: 125-32. PMID 19609923 DOI: 10.1002/Ijc.24743  0.474
2010 Enfield K, Wilson IM, Vucic EA, Chari R, Zhang Y, You M, MacAulay C, Gazdar AF, Lam S, Lam WL. Abstract A29: EYA4 is a risk- and survival-associated TSG that is deleted and hypermethylated in the earliest stages of NSCLC Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-A29  0.43
2010 Lu Y, Lubet RA, You M, Bode A, Steele VE, Townsend R, Grubbs CJ. Abstract A106: Efficacy of EGFr inhibitors gefitinib on development of OH-BBN-induced rat bladder tumors: Dose dependency and modulation of biomarkers Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-A106  0.441
2010 Grubbs CJ, Wang Y, You M, Steele V, Boring D, Lubet R. Abstract 962: Similar preventive effects of naproxen and NO-naproxen in a chemically-induced model of urinary bladder cancer: Dose dependency, gene expression and toxicity Cancer Research. 70: 962-962. DOI: 10.1158/1538-7445.Am10-962  0.365
2010 Cvetkovic D, Clapper M, Wang Y, You M, Muccio D, Grubbs C, Lubet R. Abstract 1244: RXR agonist induced changes in gene expression in liver and mammary cancers: Confirmation by RT-PCR on independent samples collected years apart Cancer Research. 70: 1244-1244. DOI: 10.1158/1538-7445.Am10-1244  0.4
2009 Wang Y, Wen W, Yi Y, Zhang Z, Lubet RA, You M. Preventive effects of bexarotene and budesonide in a genetically engineered mouse model of small cell lung cancer. Cancer Prevention Research (Philadelphia, Pa.). 2: 1059-64. PMID 19934342 DOI: 10.1158/1940-6207.Capr-09-0221  0.508
2009 Lu Y, Liu P, James M, Vikis HG, Liu H, Wen W, Franklin A, You M. Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor. Oncogene. 29: 1041-9. PMID 19915612 DOI: 10.1038/Onc.2009.396  0.493
2009 Liu Y, Liu P, Wen W, James MA, Wang Y, Bailey-Wilson JE, Amos CI, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Schwartz AG, Gazdar A, ... ... You M, et al. Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. Cancer Research. 69: 7844-50. PMID 19789337 DOI: 10.1158/0008-5472.Can-09-1833  0.483
2009 Lubet RA, Yao R, Grubbs CJ, You M, Wang Y. Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element. Chemico-Biological Interactions. 182: 22-8. PMID 19695238 DOI: 10.1016/J.Cbi.2009.08.011  0.725
2009 Liu PY, Vikis H, James M, Lu Y, Wang DL, Liu HB, Wen WD, Wang Y, You M. Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus Cancer Research. 69: 6290-6298. PMID 19622765 DOI: 10.1158/0008-5472.Can-09-0782  0.499
2009 Wang Y, Zhang Z, Garbow JR, Rowland DJ, Lubet RA, Sit D, Law F, You M. Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs. Cancer Prevention Research (Philadelphia, Pa.). 2: 634-40. PMID 19584077 DOI: 10.1158/1940-6207.Capr-09-0052  0.441
2009 Fu H, He J, Mei F, Zhang Q, Hara Y, Ryota S, Lubet RA, Chen R, Chen DR, You M. Lung cancer inhibitory effect of epigallocatechin-3-gallate is dependent on its presence in a complex mixture (polyphenon E). Cancer Prevention Research (Philadelphia, Pa.). 2: 531-7. PMID 19470785 DOI: 10.1158/1940-6207.Capr-08-0185  0.402
2009 Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, ... ... You M, et al. Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Human Molecular Genetics. 18: 3125-35. PMID 19443489 DOI: 10.1093/Hmg/Ddp231  0.347
2009 You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, et al. Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2666-74. PMID 19351763 DOI: 10.1158/1078-0432.Ccr-08-2335  0.359
2009 James MA, Lu Y, Liu Y, Vikis HG, You M. RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway. Cancer Research. 69: 2108-16. PMID 19244110 DOI: 10.1158/0008-5472.Can-08-3495  0.469
2009 Wang Y, Wen W, Yi Y, Zhang Z, Lubet RA, You M. Abstract A92: Chemoprevention of small cell lung carcinomas in mice by the retinoid X receptor agonist bexarotene Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A92  0.492
2009 Shoghi K, He J, Su Y, Yan Y, Rowland D, Garbow J, Mach R, Lubet R, You M. Multi-modality imaging of N-methyl-N-nitrosourea-induced mammary tumors by MRI and small animal PET. Cancer Research. 69: 6008. DOI: 10.1158/0008-5472.Sabcs-6008  0.364
2009 Lu Y, Liu P, Wang Y, Grubbs C, Lubet R, You M. A gene expression signature predicts chemopreventive response of an EGFR inhibitor in a rat mammary cancer model. Cancer Research. 69: 1111. DOI: 10.1158/0008-5472.Sabcs-1111  0.424
2009 Townsend R, Rohrs H, Leduc R, Yi Y, Yao R, Malone J, Edrman-Gilmore P, Grubbs C, You M, Lubet R. Identification of urinary biomarkers to distinguish tumor bearing and control rats in the methylnitrosourea (MNU) – induced model of mammary carcinogenesis: use of label-free, comparative, ultra-high resolution nano-LC mass spectrometry. Cancer Research. 69: 1109. DOI: 10.1158/0008-5472.Sabcs-1109  0.728
2008 Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, ... ... You M, et al. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. Journal of the National Cancer Institute. 100: 1326-30. PMID 18780872 DOI: 10.1093/Jnci/Djn268  0.402
2008 Anderson MW, Goodin C, Zhang Y, Kim S, Estensen RD, Wiedmann TS, Sekar P, Buncher CR, Khoury JC, Garbow JR, You M, Tichelaar JW. Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice. Carcinogenesis. 29: 1594-600. PMID 18515278 DOI: 10.1093/Carcin/Bgn129  0.51
2008 Garbow JR, Wang M, Wang Y, Lubet RA, You M. Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1363-7. PMID 18316556 DOI: 10.1158/1078-0432.Ccr-07-1757  0.318
2008 Wang Y, Zhang Z, Lu Y, Yao R, Jia D, Wen W, LaRegina M, Crist K, Lubet R, You M. Enhanced susceptibility to chemical induction of ovarian tumors in mice with a germ line p53 mutation. Molecular Cancer Research : McR. 6: 99-109. PMID 18234966 DOI: 10.1158/1541-7786.Mcr-07-0216  0.752
2007 Lu Y, Yi Y, Liu P, Wen W, James M, Wang D, You M. Common human cancer genes discovered by integrated gene-expression analysis. Plos One. 2: e1149. PMID 17989776 DOI: 10.1371/Journal.Pone.0001149  0.365
2007 Liu Y, Vikis HG, Yi Y, Futamura M, Wang Y, You M. Degradation of lung adenoma susceptibility 1, a major candidate mouse lung tumor modifier, is required for cell cycle progression. Cancer Research. 67: 10207-13. PMID 17974961 DOI: 10.1158/0008-5472.Can-07-2574  0.429
2007 Yan Y, Tan Q, Wang Y, Wang D, Jin M, Gordon T, Lubet RA, You M. Enhanced lung tumor development in tobacco smoke-exposed p53 transgenic and Kras2 heterozygous deficient mice. Inhalation Toxicology. 19: 183-7. PMID 17886066 DOI: 10.1080/08958370701496160  0.44
2007 Liu P, Vikis H, Lu Y, Wang D, You M. Large-scale in silico mapping of complex quantitative traits in inbred mice. Plos One. 2: e651. PMID 17653278 DOI: 10.1371/Journal.Pone.0000651  0.331
2007 Yan Y, Cook J, McQuillan J, Zhang G, Hitzman CJ, Wang Y, Wiedmann TS, You M. Chemopreventive effect of aerosolized polyphenon E on lung tumorigenesis in A/J mice. Neoplasia (New York, N.Y.). 9: 401-5. PMID 17534445 DOI: 10.1593/Neo.07160  0.457
2007 Vikis H, Sato M, James M, Wang D, Wang Y, Wang M, Jia D, Liu Y, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, ... ... You M, et al. EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Research. 67: 4665-70. PMID 17510392 DOI: 10.1158/0008-5472.Can-07-0217  0.404
2007 Liu J, Song KH, You MJ, Son DS, Cho SW, Kim DH. The effect of oculo-acupuncture on recovery from ethylene glycol-induced acute renal injury in dogs. The American Journal of Chinese Medicine. 35: 241-50. PMID 17436365 DOI: 10.1142/S0192415X07004783  0.655
2007 Yao R, Yi Y, Grubbs CJ, Lubet RA, You M. Gene expression profiling of chemically induced rat bladder tumors. Neoplasia (New York, N.Y.). 9: 207-21. PMID 17401461 DOI: 10.1593/Neo.06814  0.758
2007 Wang M, Zhang Z, Zhang Z, Vikis H, Yan Y, Wang Y, You M. Fine mapping and candidate gene analyses of pulmonary adenoma resistance 1, a major genetic determinant of mouse lung adenoma resistance. Cancer Research. 67: 2508-16. PMID 17363568 DOI: 10.1158/0008-5472.Can-06-3157  0.42
2007 Wang M, Vikis HG, Wang Y, Jia D, Wang D, Bierut LJ, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, ... ... You M, et al. Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1. Cancer Research. 67: 93-9. PMID 17210687 DOI: 10.1158/0008-5472.Can-06-2723  0.476
2006 Lu Y, Lemon W, Liu PY, Yi Y, Morrison C, Yang P, Sun Z, Szoke J, Gerald WL, Watson M, Govindan R, You M. A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. Plos Medicine. 3: e467. PMID 17194181 DOI: 10.1371/Journal.Pmed.0030467  0.393
2006 Yan Y, Lu Y, Wang M, Vikis H, Yao R, Wang Y, Lubet RA, You M. Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer. Molecular Cancer Research : McR. 4: 971-81. PMID 17189387 DOI: 10.1158/1541-7786.Mcr-06-0086  0.787
2006 Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, Yang Q, Bennett C, Harada Y, Stankunas K, Wang CY, He X, MacDougald OA, You M, Williams BO, et al. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell. 126: 955-68. PMID 16959574 DOI: 10.1016/J.Cell.2006.06.055  0.322
2006 Liu P, Wang Y, Vikis H, Maciag A, Wang D, Lu Y, Liu Y, You M. Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. Nature Genetics. 38: 888-95. PMID 16862160 DOI: 10.1038/Ng1849  0.491
2006 Zhang Z, Wang Y, Yao R, Li J, Lubet RA, You M. p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer. Molecular Cancer Research : McR. 4: 401-10. PMID 16778087 DOI: 10.1158/1541-7786.Mcr-06-0028  0.743
2006 Lubet RA, Christov K, You M, Yao R, Steele VE, End DW, Juliana MM, Grubbs CJ. Effects of the farnesyl transferase inhibitor R115777 (Zarnestra) on mammary carcinogenesis: prevention, therapy, and role of HaRas mutations. Molecular Cancer Therapeutics. 5: 1073-8. PMID 16648579 DOI: 10.1158/1535-7163.Mct-05-0398  0.735
2006 Wang Y, Yao R, Maciag A, Grubbs CJ, Lubet RA, You M. Organ-specific expression profiles of rat mammary gland, liver, and lung tissues treated with targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide. Molecular Cancer Therapeutics. 5: 1060-72. PMID 16648578 DOI: 10.1158/1535-7163.Mct-05-0322  0.714
2006 Yan Y, Wang Y, Tan Q, Hara Y, Yun TK, Lubet RA, You M. Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. Neoplasia (New York, N.Y.). 8: 52-8. PMID 16533426 DOI: 10.1593/Neo.05652  0.471
2006 Lu Y, Yao R, Yan Y, Wang Y, Hara Y, Lubet RA, You M. A gene expression signature that can predict green tea exposure and chemopreventive efficacy of lung cancer in mice. Cancer Research. 66: 1956-63. PMID 16488994 DOI: 10.1158/0008-5472.Can-05-3158  0.784
2006 Clark J, You M. Chemoprevention of lung cancer by tea. Molecular Nutrition & Food Research. 50: 144-51. PMID 16425282 DOI: 10.1002/Mnfr.200500135  0.45
2006 Yao R, Wang Y, Lu Y, Lemon WJ, End DW, Grubbs CJ, Lubet RA, You M. Efficacy of the farnesyltransferase inhibitor R115777 in a rat mammary tumor model: role of Ha-ras mutations and use of microarray analysis in identifying potential targets. Carcinogenesis. 27: 1420-31. PMID 16403772 DOI: 10.1093/Carcin/Bgi341  0.747
2006 Wang Y, Zhang Z, Yao R, Jia D, Wang D, Lubet RA, You M. Prevention of lung cancer progression by bexarotene in mouse models. Oncogene. 25: 1320-9. PMID 16247446 DOI: 10.1038/Sj.Onc.1209180  0.791
2006 Wang Y, Zhang Z, Lubet RA, You M. A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice. Oncogene. 25: 1277-80. PMID 16247444 DOI: 10.1038/Sj.Onc.1209182  0.487
2005 Yan Y, Wang Y, Tan Q, Lubet RA, You M. Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. Neoplasia (New York, N.Y.). 7: 1053-7. PMID 16354587 DOI: 10.1593/Neo.05532  0.496
2005 Zhang Z, Yao R, Li J, Wang Y, Boone CW, Lubet RA, You M. Induction of invasive mouse skin carcinomas in transgenic mice with mutations in both H-ras and p53. Molecular Cancer Research : McR. 3: 563-74. PMID 16254190 DOI: 10.1158/1541-7786.Mcr-05-0144  0.741
2005 Wang D, You M. Five loci, SLT1 to SLT5, controlling the susceptibility to spontaneously occurring lung cancer in mice. Cancer Research. 65: 8158-65. PMID 16166290 DOI: 10.1158/0008-5472.Can-05-1508  0.406
2005 Liu J, Song KH, Lee SE, Lee JY, Lee JI, Hayasaki M, You MJ, Kim DH. Serological and molecular survey of Dirofilaria immitis infection in stray cats in Gyunggi province, South Korea. Veterinary Parasitology. 130: 125-9. PMID 15893079 DOI: 10.1016/j.vetpar.2005.03.026  0.656
2005 Wang Y, Zhang Z, Lubet R, You M. Tobacco smoke-induced lung tumorigenesis in mutant A/J mice with alterations in K-ras, p53, or Ink4a/Arf. Oncogene. 24: 3042-9. PMID 15846305 DOI: 10.1038/Sj.Onc.1208390  0.41
2005 Wang M, Wang Y, You M, Devereux TR. Analysis of the Par2 modifier of pulmonary adenoma formation in mice. Experimental Lung Research. 31: 193-204. PMID 15828125 DOI: 10.1080/01902140490495598  0.422
2005 Yao R, Wang Y, D'Agostini F, Izzotti A, Lubet RA, You M, De Flora S. K-ras mutations in lung tumors from p53 mutant mice exposed to cigarette smoke. Experimental Lung Research. 31: 271-81. PMID 15824025 DOI: 10.1080/0190214059090386  0.752
2005 Wang M, Wang Y, You M. Identification of genetic polymorphisms through comparative DNA sequence analysis on the K-ras gene: implications for lung tumor susceptibility. Experimental Lung Research. 31: 165-77. PMID 15824019 DOI: 10.1080/01902140490495543  0.429
2005 Lubet R, Wang Y, Zhang Z, You M. Mouse models incorporating alterations in the major tumor suppressor genes P53 and P16: their use in screening for potential carcinogens, developing further relevant mouse models, and screening for potential chemopreventive and chemotherapetutic agents. Experimental Lung Research. 31: 117-33. PMID 15765922 DOI: 10.1080/01902140490495499  0.393
2005 De Flora S, Izzotti A, D'Agostini F, Bennicelli C, You M, Lubet RA, Balansky RM. Induction and modulation of lung tumors: genomic and transcriptional alterations in cigarette smoke-exposed mice. Experimental Lung Research. 31: 19-35. PMID 15765917 DOI: 10.1080/01902140490494986  0.407
2005 Crist KA, Zhang Z, You M, Gunning WT, Conran PB, Steele VE, Lubet RA. Characterization of rat ovarian adenocarcinomas developed in response to direct instillation of 7,12-dimethylbenz[a]anthracene (DMBA) coated suture. Carcinogenesis. 26: 951-7. PMID 15695234 DOI: 10.1093/Carcin/Bgi039  0.405
2005 Wang M, Futamura M, Wang Y, You M. Pas1c1 is a candidate for the mouse pulmonary adenoma susceptibility 1 locus. Oncogene. 24: 1958-63. PMID 15688036 DOI: 10.1038/Sj.Onc.1208295  0.334
2005 Tommasi S, Dammann R, Zhang Z, Wang Y, Liu L, Tsark WM, Wilczynski SP, Li J, You M, Pfeifer GP. Tumor susceptibility of Rassf1a knockout mice. Cancer Research. 65: 92-8. PMID 15665283  0.359
2004 Izzotti A, Cartiglia C, Longobardi M, Bagnasco M, Merello A, You M, Lubet RA, Flora SD. Gene Expression in the Lung of p53 Mutant Mice Exposed to Cigarette Smoke Cancer Research. 64: 8566-8572. PMID 15574763 DOI: 10.1158/0008-5472.Can-04-1420  0.407
2004 Yao R, Lemon WJ, Wang Y, Grubbs CJ, Lubet RA, You M. Altered gene expression profile in mouse bladder cancers induced by hydroxybutyl(butyl)nitrosamine. Neoplasia (New York, N.Y.). 6: 569-77. PMID 15548366 DOI: 10.1593/Neo.04223  0.744
2004 Bonner AE, Wang Y, You M. Gene expression profiling of mouse teratocarcinomas uncovers epigenetic changes associated with the transformation of mouse embryonic stem cells. Neoplasia (New York, N.Y.). 6: 490-502. PMID 15548357 DOI: 10.1593/Neo.04124  0.417
2004 Yao R, Wang Y, Lemon WJ, Lubet RA, You M. Budesonide exerts its chemopreventive efficacy during mouse lung tumorigenesis by modulating gene expressions. Oncogene. 23: 7746-52. PMID 15361829 DOI: 10.1038/Sj.Onc.1207985  0.792
2004 Yan Y, Wang M, Lemon WJ, You M. Single nucleotide polymorphism (SNP) analysis of mouse quantitative trait loci for identification of candidate genes. Journal of Medical Genetics. 41. PMID 15342708 DOI: 10.1136/Jmg.2004.020016  0.413
2004 Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Wiest JS, Fain P, Schwartz AG, You M, Franklin W, Klein C, Gazdar A, Rothschild H, Mandal D, Coons T, et al. A major lung cancer susceptibility locus maps to chromosome 6q23-25. American Journal of Human Genetics. 75: 460-74. PMID 15272417 DOI: 10.1086/423857  0.405
2004 Lubet RA, Zhang Z, Wang Y, You M. Chemoprevention of lung cancer in transgenic mice. Chest. 125: 144S-7S. PMID 15136469 DOI: 10.1378/Chest.125.5_Suppl.144S  0.435
2004 Garbow JR, Zhang Z, You M. Detection of Primary Lung Tumors in Rodents by Magnetic Resonance Imaging Cancer Research. 64: 2740-2742. PMID 15087388 DOI: 10.1158/0008-5472.Can-03-3258  0.401
2004 Meyer AM, Dwyer-Nield LD, Hurteau GJ, Keith RL, O'Leary E, You M, Bonventre JV, Nemenoff RA, Malkinson AM. Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2. Carcinogenesis. 25: 1517-24. PMID 15033900 DOI: 10.1093/Carcin/Bgh150  0.484
2004 Wang M, Devereux TR, Vikis HG, McCulloch SD, Holliday W, Anna C, Wang Y, Bebenek K, Kunkel TA, Guan K, You M. Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia. Cancer Research. 64: 1924-31. PMID 15026325 DOI: 10.1158/0008-5472.Can-03-3080  0.485
2004 Zhang Z, Wang Y, Yao R, Li J, Yan Y, La Regina M, Lemon WL, Grubbs CJ, Lubet RA, You M. Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models. Oncogene. 23: 3841-50. PMID 15021904 DOI: 10.1038/Sj.Onc.1207496  0.802
2004 Han SY, Iliopoulos D, Druck T, Guler G, Grubbs CJ, Pereira M, Zhang Z, You M, Lubet RA, Fong LY, Huebner K. CpG methylation in the Fhit regulatory region: relation to Fhit expression in murine tumors. Oncogene. 23: 3990-8. PMID 15007387 DOI: 10.1038/Sj.Onc.1207526  0.35
2004 Wang Y, Zhang Z, Yan Y, Lemon WJ, LaRegina M, Morrison C, Lubet R, You M. A chemically induced model for squamous cell carcinoma of the lung in mice: histopathology and strain susceptibility. Cancer Research. 64: 1647-54. PMID 14996723 DOI: 10.1158/0008-5472.Can-03-3273  0.447
2004 Herzog CR, Bodon N, Pittman B, Maronpot RR, Massey TE, Anderson MW, You M, Devereux TR. Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression. Oncogene. 23: 3033-9. PMID 14755239 DOI: 10.1038/Sj.Onc.1207431  0.451
2004 Bonner AE, Lemon WJ, Devereux TR, Lubet RA, You M. Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas. Oncogene. 23: 1166-76. PMID 14647414 DOI: 10.1038/Sj.Onc.1207234  0.482
2003 Bernert H, Sekikawa K, Radcliffe RA, Iraqi F, You M, Malkinson AM. Tnfa and Il-10 deficiencies have contrasting effects on lung tumor susceptibility: gender-dependent modulation of IL-10 haploinsufficiency. Molecular Carcinogenesis. 38: 117-23. PMID 14587096 DOI: 10.1002/Mc.10151  0.425
2003 Zhang Z, Futamura M, Vikis HG, Wang M, Li J, Wang Y, Guan KL, You M. Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 12642-7. PMID 14583591 DOI: 10.1073/Pnas.2133947100  0.489
2003 Li J, Zhang Z, Dai Z, Popkie AP, Plass C, Morrison C, Wang Y, You M. RASSF1A promoter methylation and Kras2 mutations in non small cell lung cancer. Neoplasia (New York, N.Y.). 5: 362-6. PMID 14511407 DOI: 10.1016/S1476-5586(03)80029-5  0.333
2003 Zhang Z, Wang Y, Lantry LE, Kastens E, Liu G, Hamilton AD, Sebti SM, Lubet RA, You M. Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf. Oncogene. 22: 6257-65. PMID 13679864 DOI: 10.1038/Sj.Onc.1206630  0.473
2003 Wang Y, Zhang Z, Kastens E, Lubet RA, You M. Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice. Cancer Research. 63: 4389-95. PMID 12907609  0.365
2003 Wang M, Lemon WJ, Liu G, Wang Y, Iraqi FA, Malkinson AM, You M. Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. Cancer Research. 63: 3317-24. PMID 12810665  0.335
2003 Bonner AE, Lemon WJ, You M. Gene expression signatures identify novel regulatory pathways during murine lung development: implications for lung tumorigenesis Journal of Medical Genetics. 40: 408-417. PMID 12807961 DOI: 10.1136/Jmg.40.6.408  0.463
2003 Lemon WJ, Swinton CH, Wang M, Berbari N, Wang Y, You M. Single nucleotide polymorphism (SNP) analysis of mouse pulmonary adenoma susceptibility loci 1–4 for identification of candidate genes Journal of Medical Genetics. 40. PMID 12676909 DOI: 10.1136/Jmg.40.4.E36  0.454
2003 Yao R, Wang Y, Lubet RA, You M. Differential gene expression in chemically induced mouse lung adenomas. Neoplasia (New York, N.Y.). 5: 41-52. PMID 12659669 DOI: 10.1016/S1476-5586(03)80016-7  0.784
2003 Li J, Zhang Z, Dai Z, Plass C, Morrison C, Wang Y, Wiest JS, Anderson MW, You M. LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer. Oncogene. 22: 1243-6. PMID 12606951 DOI: 10.1038/Sj.Onc.1206192  0.465
2003 Christov K, Ikui A, Shilkaitis A, Green A, Yao R, You M, Grubbs C, Steele V, Lubet R, Weinstein IB. Cell proliferation, apoptosis, and expression of cyclin D1 and cyclin E as potential biomarkers in tamoxifen-treated mammary tumors. Breast Cancer Research and Treatment. 77: 253-64. PMID 12602925 DOI: 10.1023/A:1021804121171  0.735
2003 De Flora S, Balansky RM, D'Agostini F, Izzotti A, Camoirano A, Bennicelli C, Zhang Z, Wang Y, Lubet RA, You M. Molecular alterations and lung tumors in p53 mutant mice exposed to cigarette smoke. Cancer Research. 63: 793-800. PMID 12591728  0.337
2002 Herzog CR, Devereux TR, Pittman B, You M. Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesis. Cancer Research. 62: 6424-9. PMID 12438228  0.319
2002 Wang D, Lemon WJ, You M. Linkage disequilibrium mapping of novel lung tumor susceptibility quantitative trait loci in mice. Oncogene. 21: 6858-65. PMID 12360413 DOI: 10.1038/Sj.Onc.1205886  0.442
2002 Lemon WJ, Bernert H, Sun H, Wang Y, You M. Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays Journal of Medical Genetics. 39: 644-655. PMID 12205107 DOI: 10.1136/Jmg.39.9.644  0.469
2002 Zhang Z, Wang Y, Herzog CR, Liu G, Lee HW, DePinho RA, You M. A strong candidate gene for the Papg1 locus on mouse chromosome 4 affecting lung tumor progression. Oncogene. 21: 5960-6. PMID 12185599 DOI: 10.1038/Sj.Onc.1205725  0.534
2002 Yao R, Wang Y, Lubet RA, You M. Differentially expressed genes associated with mouse lung tumor progression. Oncogene. 21: 5814-21. PMID 12173053 DOI: 10.1038/Sj.Onc.1205422  0.779
2002 McDoniels-Silvers AL, Stoner GD, Lubet RA, You M. Differential expression of critical cellular genes in human lung adenocarcinomas and squamous cell carcinomas in comparison to normal lung tissues. Neoplasia (New York, N.Y.). 4: 141-50. PMID 11896569 DOI: 10.1038/Sj.Neo.7900217  0.43
2002 Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM. Corrigendum to “Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells” Cancer Letters. 180: 223. DOI: 10.1016/S0304-3835(02)00016-2  0.364
2001 Yao R, Wang Y, You M. Chromosome mapping and sequence variation of the murine Ras effector gene Nore1. Cytogenetics and Cell Genetics. 95: 126-8. PMID 11978988 DOI: 10.1159/000057035  0.693
2001 Wang Y, Hu L, Yao R, Wang M, Crist KA, Grubbs CJ, Johanning GL, Lubet RA, You M. Altered gene expression profile in chemically induced rat mammary adenocarcinomas and its modulation by an aromatase inhibitor. Oncogene. 20: 7710-21. PMID 11753649 DOI: 10.1038/Sj.Onc.1204941  0.753
2001 Zhang Z, Wang Y, Vikis HG, Johnson L, Liu G, Li J, Anderson MW, Sills RC, Hong HL, Devereux TR, Jacks T, Guan KL, You M. Wildtype Kras2 can inhibit lung carcinogenesis in mice. Nature Genetics. 29: 25-33. PMID 11528387 DOI: 10.1038/Ng721  0.523
2001 Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM. Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells. Cancer Letters. 168: 165-72. PMID 11403921 DOI: 10.1016/S0304-3835(01)00480-3  0.394
2001 Herzog CR, Crist KA, Sabourin CLK, Kelloff GJ, Boone CW, Stoner GD, You M. Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas Molecular Carcinogenesis. 30: 159-168. PMID 11301476 DOI: 10.1002/Mc.1024  0.436
2001 McDoniels-Silvers AL, Herzog CR, Tyson FL, Malkinson AM, You M. Inactivation of both Rb and p53 pathways in mouse lung epithelial cell lines. Experimental Lung Research. 27: 297-318. PMID 11293330 DOI: 10.1080/019021401300054064  0.374
2001 Wang Y, You M, Wang Y. Alternative splicing of the K-ras gene in mouse tissues and cell lines. Experimental Lung Research. 27: 255-267. PMID 11293328 DOI: 10.1080/019021401300054028  0.323
2001 Zhang Z, Lin L, Liu G, Wang M, Hill J, Wang Y, You M, Devereux TR. Fine mapping and characterization of candidate lung tumor resistance genes for the Par2 locus on mouse chromosome 18. Experimental Lung Research. 26: 627-39. PMID 11195460 DOI: 10.1080/01902140150216710  0.454
2001 Lin L, Wang Y, Bergman G, Kelloff GJ, Lubet RA, You M. Detection of differentially expressed genes in mouse lung adenocarcinomas Experimental Lung Research. 27: 217-229. DOI: 10.1080/019021401300053966  0.442
2001 Jacoby RF, Cole CE, Lubet RA, You M. Effects of the nonspecific COX1 and COX2 inhibitor piroxicam and the ornithine decarboxylase inhibitor difluoromethylornithine (DFMO) on development of intestinal tumors in mice bearing germline alterations in the MSH2 or APC genes Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80594-X  0.399
2000 Lantry LE, Zhang Z, Crist KA, Wang Y, Hara M, Zeeck A, Lubet RA, You M. Chemopreventive efficacy of promising farnesyltransferase inhibitors Experimental Lung Research. 26: 773-790. PMID 11195470 DOI: 10.1080/01902140150216819  0.494
2000 Yao R, Rioux N, Castonguay A, You M. Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis. Experimental Lung Research. 26: 731-42. PMID 11195467 DOI: 10.1080/01902140150216783  0.768
2000 Liu J, Gu P, Bergman G, Kelloff GJ, Boone CW, You M, Wang Y. Detection of genetic alterations in mouse lung adenocarcinomas by two-dimensional gel electrophoresis. Experimental Lung Research. 26: 651-8. PMID 11195462 DOI: 10.1080/01902140150216738  0.769
2000 Lubet RA, Zhang Z, Wiseman RW, You M. Use of p53 transgenic mice in the development of cancer models for multiple purposes Experimental Lung Research. 26: 581-593. PMID 11195457 DOI: 10.1080/01902140150216684  0.492
2000 Lantry LE, Zhang Z, Yao R, Crist KA, Wang Y, Ohkanda J, Hamilton AD, Sebti SM, Lubet RA, You M. Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis. 21: 113-6. PMID 10607742 DOI: 10.1093/Carcin/21.1.113  0.77
1999 Herzog CR, Noh S, Lantry LE, Guan KL, You M. Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesis. Molecular Carcinogenesis. 25: 92-8. PMID 10365910 DOI: 10.1002/(Sici)1098-2744(199906)25:2<92::Aid-Mc3>3.0.Co;2-2  0.496
1999 Lantry LE, Zhang Z, Crist KA, Wang Y, Kelloff GJ, Lubet RA, You M. 5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model Carcinogenesis. 20: 343-346. PMID 10069475 DOI: 10.1093/Carcin/20.2.343  0.474
1999 You M, Bergman G. Preclinical and clinical models of lung cancer chemoprevention. Hematology/Oncology Clinics of North America. 12: 1037-53. PMID 9888020 DOI: 10.1016/S0889-8588(05)70040-X  0.424
1998 Festing MF, Lin L, Devereux TR, Gao F, Yang A, Anna CH, White CM, Malkinson AM, You M. At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice. Genomics. 53: 129-36. PMID 9790761 DOI: 10.1006/Geno.1998.5450  0.418
1998 Liu Q, Wang Y, Crist KA, Wang ZY, Lou YR, Huang MT, Conney AH, You M. Effect of green tea on p53 mutation distribution in ultraviolet B radiation-induced mouse skin tumors Carcinogenesis. 19: 1257-1262. PMID 9683186 DOI: 10.1093/Carcin/19.7.1257  0.413
1998 Sabourin CL, Wang QS, Ralston SL, Evans J, Coate J, Herzog CR, Jones SL, Weghorst CM, Kelloff GJ, Lubet RA, You M, Stoner GD. Expression of cell cycle proteins in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumors. Experimental Lung Research. 24: 499-521. PMID 9659580 DOI: 10.3109/01902149809087383  0.491
1998 Lin L, Festing MF, Devereux TR, Crist KA, Christiansen SC, Wang Y, Yang A, Svenson K, Paigen B, Malkinson AM, You M. Additional evidence that the K-ras protooncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene. Experimental Lung Research. 24: 481-97. PMID 9659579 DOI: 10.3109/01902149809087382  0.426
1998 Oreffo VI, Robinson S, You M, Wu MC, Malkinson AM. Decreased expression of the adenomatous polyposis coli (Apc) and mutated in colorectal cancer (Mcc) genes in mouse lung neoplasia. Molecular Carcinogenesis. 21: 37-49. PMID 9473770 DOI: 10.1002/(Sici)1098-2744(199801)21:1<37::Aid-Mc6>3.0.Co;2-M  0.495
1997 Crist KA, Wang Y, Lubet RA, Steele VE, Kelloff GJ, You M. Effect of early vs. late administration of 4-hydroxyphenylretinamide (4-HPR) on N-methyl-N-nitrosourea (MNU)-induced mammary tumorigenesis. Journal of Cellular Biochemistry. Supplement. 27: 92-9. PMID 9591198 DOI: 10.1002/(Sici)1097-4644(1997)27+<92::Aid-Jcb15>3.0.Co;2-N  0.379
1997 Lantry LE, Zhang Z, Gao F, Crist KA, Wang Y, Kelloff GJ, Lubet RA, You M. Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung Journal of Cellular Biochemistry. 67: 20-25. PMID 9591189 DOI: 10.1002/(Sici)1097-4644(1997)27+<20::Aid-Jcb6>3.0.Co;2-3  0.435
1997 Devereux TR, Anna CH, Patel AC, White CM, Festing MF, You M. Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genes. Carcinogenesis. 18: 1751-5. PMID 9328171 DOI: 10.1093/Carcin/18.9.1751  0.504
1997 Matzinger SA, Chen B, Wang Y, Crist KA, Stoner GD, Kelloff GJ, Lubet RA, You M. Tissue-specific expression of the K-ras allele from the A/J parent in (A/J x TSG-p53) F1 mice Gene. 188: 261-269. PMID 9133601 DOI: 10.1016/S0378-1119(96)00821-9  0.417
1997 Herzog CR, You M. Sequence variation and chromosomal mapping of the murine Cdkn2a tumor suppressor gene Mammalian Genome. 8: 65-66. PMID 9021155 DOI: 10.1007/S003359900352  0.313
1997 Gerhäuser C, You M, Liu J, Moriarty RM, Hawthorne M, Mehta RG, Moon RC, Pezzuto JM. Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes. Cancer Research. 57: 272-8. PMID 9000567  0.707
1997 Boone CW, You M. Progress in cancer chemoprevention: Biomarkers and cohorts Journal of Cellular Biochemistry. 67. DOI: 10.1002/(Sici)1097-4644(1997)28/29+3.0.Co;2-G  0.313
1997 Herzog CR, Lubet RA, You M. Genetic alterations in mouse lung tumors: Implications for cancer chemoprevention Journal of Cellular Biochemistry. 67: 49-63. DOI: 10.1002/(Sici)1097-4644(1997)28/29+<49::Aid-Jcb6>3.0.Co;2-W  0.538
1997 Hu L, Lin L, Crist KA, Kelloff GJ, Steele VE, Lubet RA, You M, Wang Y. Detection of differentially expressed genes in Methylnitrosourea-induced rat mammary adenocarcinomas Journal of Cellular Biochemistry. 67: 117-124. DOI: 10.1002/(Sici)1097-4644(1997)28/29+<117::Aid-Jcb13>3.0.Co;2-E  0.36
1997 Boone CW, You M. Progress in cancer chemoprevention: Agents Journal of Cellular Biochemistry. 67. DOI: 10.1002/(Sici)1097-4644(1997)27+3.0.Co;2-B  0.306
1996 Liu J, Wang Y, Gu P, Patrick J, Crist KA, Sabourin CL, Stoner GD, Mitchell MF, Fanning JD, Kim K, Goldblatt PJ, Kelloff GJ, Boone CW, You M. Detection of genomic alterations in human cervical cancer by two-dimensional gel electrophoresis. Journal of Cellular Biochemistry. Supplement. 25: 41-8. PMID 9027597 DOI: 10.1002/(Sici)1097-4644(1996)25+<41::Aid-Jcb6>3.0.Co;2-2  0.701
1996 Crist KA, Fuller RD, Chaudhuri B, Chaudhuri P, You M. Brief communication, P53 accumulation in N-methyl-N-nitrosourea-induced rat mammary tumors. Toxicologic Pathology. 24: 370-5. PMID 8736394 DOI: 10.1177/019262339602400314  0.386
1996 Herzog CR, Chen B, Wang Y, Schut HA, You M. Loss of heterozygosity on chromosomes 1, 11, 12, and 14 in hybrid mouse lung adenocarcinomas. Molecular Carcinogenesis. 16: 83-90. PMID 8645430 DOI: 10.1002/(Sici)1098-2744(199606)16:2<83::Aid-Mc4>3.0.Co;2-O  0.37
1995 Mehta RG, Liu J, Constantinou A, Thomas CF, Hawthorne M, You M, Gerhüser C, Pezzuto JM, Moon RC, Moriarty RM. Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. Carcinogenesis. 16: 399-404. PMID 7859373 DOI: 10.1093/Carcin/16.2.399  0.707
1995 Matzinger SA, Crist KA, Stoner GD, Anderson MW, Pereira MA, Steele VE, Kelloff GJ, Lubet RA, You M. K-ras mutations in lung tumors from A/J and A/J x TSG-p53 F1 mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothiocyanate. Carcinogenesis. 16: 2487-92. PMID 7586156 DOI: 10.1093/Carcin/16.10.2487  0.472
1994 Chen B, Johanson L, Wiest JS, Anderson MW, You M. The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 91: 1589-1593. PMID 8108449 DOI: 10.1073/Pnas.91.4.1589  0.407
1994 Chen B, You L, Wang Y, Stoner GD, You M. Allele-specific activation and expression of the K-ras gene in hybrid mouse lung tumors induced by chemical carcinogens. Carcinogenesis. 15: 2031-5. PMID 7923598 DOI: 10.1093/Carcin/15.9.2031  0.466
1994 Matzinger SA, Gunning WT, You M, Castonguay A. Ki-ras mutations in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-initiated and butylated hydroxytoluene-promoted lung tumors in A/J mice. Molecular Carcinogenesis. 11: 42-8. PMID 7916989 DOI: 10.1002/Mc.2940110108  0.494
1993 You M, Wang Y, Nash B, Stoner GD. K-ras mutations in benzotrichloride-induced lung tumors of A/J mice. Carcinogenesis. 14: 1247-9. PMID 8508514 DOI: 10.1093/Carcin/14.6.1247  0.465
1993 Chen B, Liu L, Castonguay A, Maronpot RR, Anderson MW, You M. Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors. Carcinogenesis. 14: 1603-8. PMID 8353844 DOI: 10.1093/Carcin/14.8.1603  0.455
1993 Herzog CR, Schut HA, Maronpot RR, You M. ras mutations in 2-amino-3-methylimidazo-[4,5-f]quinoline-induced tumors in the CDF1 mouse. Molecular Carcinogenesis. 8: 202-7. PMID 8216739 DOI: 10.1002/Mc.2940080311  0.452
1992 Anderson MW, Reynolds SH, You M, Maronpot RM. Role of proto-oncogene activation in carcinogenesis. Environmental Health Perspectives. 98: 13-24. PMID 1486840 DOI: 10.1289/Ehp.929813  0.455
1992 You M, Wang Y, Lineen AM, Gunning WT, Stoner GD, Anderson MW. Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine. Carcinogenesis. 13: 1583-6. PMID 1394843 DOI: 10.1093/Carcin/13.9.1583  0.471
1992 You M, Wang Y, Stoner G, You L, Maronpot R, Reynolds SH, Anderson M. Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids. Proceedings of the National Academy of Sciences of the United States of America. 89: 5804-8. PMID 1352876 DOI: 10.1073/Pnas.89.13.5804  0.471
1991 Anderson MW, You M, Reynolds SH. Proto-oncogene activation in rodent and human tumors. Advances in Experimental Medicine and Biology. 283: 235-43. PMID 2068988 DOI: 10.1007/978-1-4684-5877-0_23  0.389
1991 You M, Wang Y, Lineen A, Stoner GD, You LA, Maronpot RR, Anderson MW. Activation of protooncogenes in mouse lung tumors. Experimental Lung Research. 17: 389-400. PMID 2050038 DOI: 10.3109/01902149109064426  0.502
1989 You M, Candrian U, Maronpot RR, Stoner GD, Anderson MW. Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse Proceedings of the National Academy of Sciences of the United States of America. 86: 3070-3074. PMID 2654935 DOI: 10.1073/Pnas.86.9.3070  0.488
1986 Stoner GD, You M, Morgan MA, Superczynski MJ. Lung tumor induction in strain A mice with benzotrichloride Cancer Letters. 33: 167-173. PMID 3791187 DOI: 10.1016/0304-3835(86)90021-2  0.449
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