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Alan W. Lau, Ph.D. - Publications

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Gasser JA, Inuzuka H, Lau AW, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Molecular Cell. 56: 595-607. PMID 25458846 DOI: 10.1016/J.Molcel.2014.09.023  0.337
2014 Dai X, Liu P, Lau AW, Liu Y, Inuzuka H. Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesis. Cancer Medicine. 3: 1211-24. PMID 25116380 DOI: 10.1002/Cam4.298  0.389
2013 Fukushima H, Ogura K, Wan L, Lu Y, Li V, Gao D, Liu P, Lau AW, Wu T, Kirschner MW, Inuzuka H, Wei W. SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression. Cell Reports. 4: 803-16. PMID 23972993 DOI: 10.1016/J.Celrep.2013.07.031  0.394
2013 Lau AW, Inuzuka H, Fukushima H, Wan L, Liu P, Gao D, Sun Y, Wei W. Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. Cell Research. 23: 947-61. PMID 23670162 DOI: 10.1038/Cr.2013.67  0.405
2012 Inuzuka H, Gao D, Finley LW, Yang W, Wan L, Fukushima H, Chin YR, Zhai B, Shaik S, Lau AW, Wang Z, Gygi SP, Nakayama K, Teruya-Feldstein J, Toker A, et al. Acetylation-dependent regulation of Skp2 function. Cell. 150: 179-93. PMID 22770219 DOI: 10.1016/J.Cell.2012.05.038  0.417
2012 Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W. SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction. Cell Reports. 1: 434-43. PMID 22708077 DOI: 10.1016/J.Celrep.2012.04.002  0.455
2012 Lau AW, Fukushima H, Wei W. The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis. Frontiers in Bioscience (Landmark Edition). 17: 2197-212. PMID 22652772 DOI: 10.2741/4045  0.358
2012 Min SH, Lau AW, Lee TH, Inuzuka H, Wei S, Huang P, Shaik S, Lee DY, Finn G, Balastik M, Chen CH, Luo M, Tron AE, Decaprio JA, Zhou XZ, et al. Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase. Molecular Cell. 46: 771-83. PMID 22608923 DOI: 10.1016/J.Molcel.2012.04.012  0.431
2011 Erickson-Johnson MR, Chou MM, Evers BR, Roth CW, Seys AR, Jin L, Ye Y, Lau AW, Wang X, Oliveira AM. Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 1427-33. PMID 21826056 DOI: 10.1038/Labinvest.2011.118  0.676
2011 Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W. Mcl-1 ubiquitination and destruction. Oncotarget. 2: 239-44. PMID 21608150 DOI: 10.18632/Oncotarget.242  0.38
2011 Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, et al. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. Nature. 471: 104-9. PMID 21368833 DOI: 10.1038/Nature09732  0.366
2010 Lau AW, Pringle LM, Quick L, Riquelme DN, Ye Y, Oliveira AM, Chou MM. TRE17/ubiquitin-specific protease 6 (USP6) oncogene translocated in aneurysmal bone cyst blocks osteoblastic maturation via an autocrine mechanism involving bone morphogenetic protein dysregulation. The Journal of Biological Chemistry. 285: 37111-20. PMID 20864534 DOI: 10.1074/Jbc.M110.175133  0.618
2010 Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, et al. Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction. Molecular Cell. 39: 797-808. PMID 20832730 DOI: 10.1016/J.Molcel.2010.08.016  0.423
2010 Ye Y, Pringle LM, Lau AW, Riquelme DN, Wang H, Jiang T, Lev D, Welman A, Blobel GA, Oliveira AM, Chou MM. TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB. Oncogene. 29: 3619-29. PMID 20418905 DOI: 10.1038/Onc.2010.116  0.62
2010 Kadauke S, Lamonica JM, Lau A, Chou M, Blobel G. A Potential Epigenetic Bookmarking Function for the Hematopoietic Transcription Factor GATA-1. Blood. 116: 2601-2601. DOI: 10.1182/Blood.V116.21.2601.2601  0.672
2009 Blobel GA, Kadauke S, Wang E, Lau AW, Zuber J, Chou MM, Vakoc CR. A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit. Molecular Cell. 36: 970-83. PMID 20064463 DOI: 10.1016/J.Molcel.2009.12.001  0.651
2008 Lau AW, Chou MM. The adaptor complex AP-2 regulates post-endocytic trafficking through the non-clathrin Arf6-dependent endocytic pathway. Journal of Cell Science. 121: 4008-17. PMID 19033387 DOI: 10.1242/Jcs.033522  0.641
2005 Shen C, Ye Y, Robertson SE, Lau AW, Mak DO, Chou MM. Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6. The Journal of Biological Chemistry. 280: 35967-73. PMID 16127172 DOI: 10.1074/Jbc.M505220200  0.696
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