| Year |
Citation |
Score |
| 2024 |
Hebert JD, Xu H, Tang YJ, Ruiz PA, Detrick C, Wang J, Hughes NW, Donosa O, Andrejka L, Karmakar S, Aboiralor I, Cong L, Sage J, Petrov DA, Winslow MM. Modeling the genomic complexity of human cancer using Cas12a mice. Biorxiv : the Preprint Server For Biology. PMID 38496463 DOI: 10.1101/2024.03.07.583774 |
0.32 |
|
| 2024 |
Oser MG, MacPherson D, Oliver TG, Sage J, Park KS. Genetically-engineered mouse models of small cell lung cancer: the next generation. Oncogene. PMID 38191672 DOI: 10.1038/s41388-023-02929-7 |
0.323 |
|
| 2023 |
Ko JH, Lambert KE, Bhattacharya D, Lee MC, Colon CI, Hauser H, Sage J. Small cell lung cancer plasticity enables NFIB-independent metastasis. Cancer Research. PMID 37963187 DOI: 10.1158/0008-5472.CAN-23-1079 |
0.346 |
|
| 2023 |
Hammond T, Sage J. Monitoring the Cell Cycle of Tumor Cells in Mouse Models of Human Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 37460156 DOI: 10.1101/cshperspect.a041383 |
0.352 |
|
| 2023 |
Pearsall SM, Williamson SC, Humphrey S, Hughes E, Morgan D, García Marqués FJ, Awanis G, Carroll R, Burks L, Shue YT, Bermudez A, Frese KK, Galvin M, Carter M, Priest L, ... ... Sage J, et al. Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 37455012 DOI: 10.1016/j.jtho.2023.07.012 |
0.332 |
|
| 2023 |
Sivakumar S, Moore JA, Montesion M, Sharaf R, Lin DI, Colon CI, Fleischmann Z, Ebot EM, Newberg JY, Mills JM, Hegde PS, Pan Q, Dowlati A, Frampton GM, Sage J, et al. Integrative analysis of a large real-world cohort of small cell lung cancer identifies distinct genetic subtypes and insights into histological transformation. Cancer Discovery. PMID 37062002 DOI: 10.1158/2159-8290.CD-22-0620 |
0.313 |
|
| 2023 |
Lee MC, Cai H, Murray CW, Li C, Shue YT, Andrejka L, He AL, Holzem AME, Drainas AP, Ko JH, Coles GL, Kong C, Zhu S, Zhu C, Wang J, ... ... Sage J, et al. A multiplexed in vivo approach to identify driver genes in small cell lung cancer. Cell Reports. 42: 111990. PMID 36640300 DOI: 10.1016/j.celrep.2023.111990 |
0.37 |
|
| 2022 |
Kim JW, Ko JH, Sage J. DLL3 regulates Notch signaling in small cell lung cancer. Iscience. 25: 105603. PMID 36483011 DOI: 10.1016/j.isci.2022.105603 |
0.378 |
|
| 2022 |
Rovira-Clavé X, Drainas AP, Jiang S, Bai Y, Baron M, Zhu B, Dallas AE, Lee MC, Chu TP, Holzem A, Ayyagari R, Bhattacharya D, McCaffrey EF, Greenwald NF, Markovic M, ... ... Sage J, et al. Spatial epitope barcoding reveals clonal tumor patch behaviors. Cancer Cell. PMID 36240778 DOI: 10.1016/j.ccell.2022.09.014 |
0.345 |
|
| 2022 |
Shue YT, Drainas AP, Li NY, Pearsall SM, Morgan D, Sinnott-Armstrong N, Hipkins SQ, Coles GL, Lim JS, Oro AE, Simpson KL, Dive C, Sage J. A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs. Nature Communications. 13: 2690. PMID 35577801 DOI: 10.1038/s41467-022-30416-2 |
0.314 |
|
| 2022 |
Armstrong N, Storey CM, Noll SE, Margulis K, Soe MH, Xu H, Yeh B, Fishbein L, Kebebew E, Howitt BE, Zare RN, Sage J, Annes JP. SDHB knockout and succinate accumulation are insufficient for tumorigenesis but dual SDHB/NF1 loss yields SDHx-like pheochromocytomas. Cell Reports. 38: 110453. PMID 35235785 DOI: 10.1016/j.celrep.2022.110453 |
0.303 |
|
| 2021 |
Doan A, Arand J, Gong D, Drainas AP, Shue YT, Lee MC, Zhang S, Walter DM, Chaikovsky AC, Feldser DM, Vogel H, Dow LE, Skotheim JM, Sage J. RB depletion is required for the continuous growth of tumors initiated by loss of RB. Plos Genetics. 17: e1009941. PMID 34879057 DOI: 10.1371/journal.pgen.1009941 |
0.382 |
|
| 2021 |
Sengupta D, Zeng L, Li Y, Hausmann S, Ghosh D, Yuan G, Nguyen TN, Lyu R, Caporicci M, Morales Benitez A, Coles GL, Kharchenko V, Czaban I, Azhibek D, Fischle W, ... ... Sage J, et al. NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis. Molecular Cell. PMID 34555356 DOI: 10.1016/j.molcel.2021.08.034 |
0.696 |
|
| 2020 |
Tammela T, Sage J. Investigating Tumor Heterogeneity in Mouse Models. Annual Review of Cancer Biology. 4: 99-119. PMID 34164589 DOI: 10.1146/annurev-cancerbio-030419-033413 |
0.364 |
|
| 2020 |
Ko J, Winslow MM, Sage J. Mechanisms of small cell lung cancer metastasis. Embo Molecular Medicine. e13122. PMID 33296145 DOI: 10.15252/emmm.202013122 |
0.343 |
|
| 2020 |
Rubin SM, Sage J, Skotheim JM. Integrating Old and New Paradigms of G1/S Control. Molecular Cell. PMID 32946743 DOI: 10.1016/J.Molcel.2020.08.020 |
0.38 |
|
| 2020 |
Ferone G, Lee MC, Sage J, Berns A. Cells of origin of lung cancers: lessons from mouse studies. Genes & Development. 34: 1017-1032. PMID 32747478 DOI: 10.1101/Gad.338228.120 |
0.435 |
|
| 2020 |
Coles GL, Cristea S, Webber JT, Levin RS, Moss SM, He A, Sangodkar J, Hwang YC, Arand J, Drainas AP, Mooney NA, Demeter J, Spradlin JN, Mauch B, Le V, ... ... Sage J, et al. Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells. Cancer Cell. PMID 32531271 DOI: 10.1016/J.Ccell.2020.05.003 |
0.416 |
|
| 2020 |
Wang Z, Hausmann S, Lyu R, Li TM, Lofgren SM, Flores NM, Fuentes ME, Caporicci M, Yang Z, Meiners MJ, Cheek MA, Howard SA, Zhang L, Elias JE, Kim MP, ... ... Sage J, et al. SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy. Cancer Cell. PMID 32442403 DOI: 10.1016/J.Ccell.2020.04.014 |
0.671 |
|
| 2020 |
Riess JW, Jahchan NS, Das M, Zach Koontz M, Kunz PL, Wakelee HA, Schatzberg A, Sage J, Neal JW. A PHASE IIA STUDY REPOSITIONING DESIPRAMINE IN SMALL CELL LUNG CANCER AND OTHER HIGH-GRADE NEUROENDOCRINE TUMORS. Cancer Treatment and Research Communications. 23: 100174. PMID 32413603 DOI: 10.1016/J.Ctarc.2020.100174 |
0.431 |
|
| 2020 |
Poirier JT, George J, Owonikoko TK, Berns A, Brambilla E, Byers LA, Carbone D, Chen HJ, Christensen CL, Dive C, Farago AF, Govindan R, Hann C, Hellmann MD, Horn L, ... ... Sage J, et al. New approaches to small cell lung cancer therapy : from the laboratory to the clinic. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 32018053 DOI: 10.1016/J.Jtho.2020.01.016 |
0.401 |
|
| 2020 |
Cristea S, Coles GL, Hornburg D, Gershkovitz M, Arand J, Cao S, Sen T, Williamson SC, Kim JW, Drainas AP, He A, Le Cam L, Byers LA, Snyder MP, Contrepois K, ... Sage J, et al. The MEK5-ERK5 kinase axis controls lipid metabolism in small cell lung cancer. Cancer Research. PMID 31969375 DOI: 10.1158/0008-5472.Can-19-1027 |
0.385 |
|
| 2020 |
Sage J. Abstract IA05: Signaling networks in small-cell lung cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Ia05 |
0.387 |
|
| 2020 |
Qu F, Pasca A, Kong C, Winslow M, Sage J. B23 Unraveling the Mechanisms of Small-Cell Lung Cancer Brain Metastasis Journal of Thoracic Oncology. 15. DOI: 10.1016/J.Jtho.2019.12.089 |
0.356 |
|
| 2019 |
Yang D, Qu F, Cai H, Chuang CH, Lim JS, Jahchan N, Grüner BM, S Kuo C, Kong C, Oudin MJ, Winslow MM, Sage J. Axon-like protrusions promote small cell lung cancer migration and metastasis. Elife. 8. PMID 31833833 DOI: 10.7554/Elife.50616 |
0.392 |
|
| 2019 |
Wooten DJ, Groves SM, Tyson DR, Liu Q, Lim JS, Albert R, Lopez CF, Sage J, Quaranta V. Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers. Plos Computational Biology. 15: e1007343. PMID 31671086 DOI: 10.1371/Journal.Pcbi.1007343 |
0.442 |
|
| 2019 |
Hsu J, Arand J, Chaikovsky A, Mooney NA, Demeter J, Brison CM, Oliverio R, Vogel H, Rubin SM, Jackson PK, Sage J. E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family. Nature Communications. 10: 2939. PMID 31270324 DOI: 10.1038/S41467-019-10901-X |
0.427 |
|
| 2019 |
Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, et al. Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nature Reviews. Cancer. PMID 31175338 DOI: 10.1038/S41568-019-0164-2 |
0.373 |
|
| 2019 |
Marshall AE, Roes MV, Passos DT, DeWeerd MC, Chaikovsky AC, Sage J, Howlett CJ, Dick FA. deletion in RB-pathway disrupted cells results in DNA damage and cancer progression. Molecular and Cellular Biology. PMID 31138663 DOI: 10.1128/Mcb.00105-19 |
0.424 |
|
| 2019 |
Rubin SM, Sage J. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets. Nature. 569: 343-344. PMID 31076732 DOI: 10.1038/D41586-019-01319-Y |
0.347 |
|
| 2019 |
Topacio BR, Zatulovskiy E, Cristea S, Xie S, Tambo CS, Rubin SM, Sage J, Kõivomägi M, Skotheim JM. Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein's C-Terminal Helix. Molecular Cell. PMID 30982746 DOI: 10.1016/J.Molcel.2019.03.020 |
0.36 |
|
| 2019 |
Kastenhuber ER, Craig J, Ramsey J, Sullivan KM, Sage J, de Oliveira S, Riehle KJ, Scott JD, Gordan JD, Bardeesy N, Abou-Alfa GK. Road map for fibrolamellar carcinoma: progress and goals of a diversified approach. Journal of Hepatocellular Carcinoma. 6: 41-48. PMID 30951568 DOI: 10.2147/Jhc.S194764 |
0.328 |
|
| 2019 |
Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, et al. Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nature Reviews. Cancer. PMID 30926931 DOI: 10.1038/S41568-019-0133-9 |
0.433 |
|
| 2019 |
Kim J, Sage J. Taking SCLC on a Bad LSD(1) Trip One NOTCH Further. Trends in Molecular Medicine. PMID 30852141 DOI: 10.1016/J.Molmed.2019.02.009 |
0.41 |
|
| 2019 |
Sen T, Rodriguez BL, Chen L, Della Corte C, Morikawa N, Fujimoto J, Cristea S, Nguyen T, Diao L, Li L, Fan Y, Yang Y, Wang J, Glisson BS, Wistuba II, ... Sage J, et al. Targeting DNA damage response promotes anti-tumor immunity through STING-mediated T-cell activation in small cell lung cancer. Cancer Discovery. PMID 30777870 DOI: 10.1158/2159-8290.Cd-18-1020 |
0.39 |
|
| 2019 |
Yang D, Qu F, Cai H, Chuang C, Lim JS, Jahchan N, Grüner BM, Kuo CS, Kong C, Oudin MJ, Winslow MM, Sage J. Author response: Axon-like protrusions promote small cell lung cancer migration and metastasis Elife. DOI: 10.7554/Elife.50616.Sa2 |
0.359 |
|
| 2019 |
Sen T, Rodriguez BL, Chen L, Morikawa N, Fujimoto J, Diao L, Fan Y, Wang J, Glisson BS, Wistuba I, Sage J, Heymach JV, Gibbons DL, Byers LA. Abstract A153: Targeting DNA damage response upregulates PD-L1 level and promotes antitumor immunity in small-cell lung cancer Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A153 |
0.34 |
|
| 2019 |
Lechler C, Dong S, Manmadhan S, Rösner T, Kohnke-Ertel B, Steiger K, Mogler C, Sage J, Schmid R, Ehmer U. THU-458-Identification of relevant oncogenes in RAS-activated primary liver cancer using a targeted screening approach Journal of Hepatology. 70: e361. DOI: 10.1016/S0618-8278(19)30705-4 |
0.307 |
|
| 2018 |
Yang D, Denny SK, Greenside PG, Chaikovsky AC, Brady JJ, Ouadah Y, Granja JM, Jahchan NS, Lim JS, Kwok S, Kong CS, Berghoff AS, Schmitt A, Reinhardt HC, Park KS, ... ... Sage J, et al. Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin. Cancer Discovery. PMID 30228179 DOI: 10.1158/2159-8290.Cd-17-0987 |
0.445 |
|
| 2018 |
Ponath P, Menezes DL, Pan C, Chen B, Oyasu M, Strachan D, LeBlanc H, Sun H, Wang XT, Rangan V, Deshpande S, Cristea S, Park KS, Sage J, Cardarelli PM. A novel, fully human anti-fucosyl-GM1 antibody demonstrates potent in vitro and in vivo antitumor activity in preclinical models of small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30021910 DOI: 10.1158/1078-0432.Ccr-18-0018 |
0.419 |
|
| 2018 |
Chaikovsky AC, Sage J. BEYOND THE CELL CYCLE: ENHANCING THE IMMUNE SURVEILLANCE OF TUMORS VIA CDK4/6 INHIBITION. Molecular Cancer Research : McR. PMID 29934327 DOI: 10.1158/1541-7786.Mcr-18-0201 |
0.429 |
|
| 2018 |
Dick FA, Goodrich DW, Sage J, Dyson NJ. Non-canonical functions of the RB protein in cancer. Nature Reviews. Cancer. PMID 29692417 DOI: 10.1038/S41568-018-0008-5 |
0.437 |
|
| 2018 |
Shue YT, Lim JS, Sage J. Tumor heterogeneity in small cell lung cancer defined and investigated in pre-clinical mouse models. Translational Lung Cancer Research. 7: 21-31. PMID 29535910 DOI: 10.21037/Tlcr.2018.01.15 |
0.429 |
|
| 2018 |
Oliverio R, Sage J. [Dual tumor suppressive and oncogenic roles for Notch signaling in small cell lung cancer]. Medecine Sciences : M/S. 34: 24-26. PMID 29384090 DOI: 10.1051/Medsci/20183401007 |
0.458 |
|
| 2018 |
Sunshine JC, Jahchan NS, Sage J, Choi J. Are there multiple cells of origin of Merkel cell carcinoma? Oncogene. PMID 29321666 DOI: 10.1038/S41388-017-0073-3 |
0.399 |
|
| 2018 |
Yang D, Winslow MM, Sage J. Abstract IA07: Influence of cancer initiation on tumor progression in SCLC Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-Ia07 |
0.47 |
|
| 2018 |
Lim JS, Yang D, Shue YT, Winslow M, Sage J. Abstract IA12: Intra- and intertumoral heterogeneity and response to therapy in mouse models of SCLC Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-Ia12 |
0.498 |
|
| 2018 |
Sen T, Chen L, Rodriguez BL, Li L, Li Y, Fan Y, Glisson B, Wang J, Piwnica-Worms H, Sage J, Heymach JV, Gibbons DL, Byers LA. Abstract A108: DNA damage repair targeting upregulates PD-L1 level and potentiates the effect of PD-L1 blockade in small cell lung cancer Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A108 |
0.36 |
|
| 2018 |
Rösner T, Lechler C, Birgit K, Steiger K, Mogler C, Saur D, Sage J, Schmid R, Ehmer U. KRAS-dependent AKT signaling drives hepatocyte proliferation to promote tumor development in a genetic model of liver cancer Journal of Hepatology. 68: S689. DOI: 10.1016/S0168-8278(18)31639-8 |
0.399 |
|
| 2017 |
Zingone A, Brown D, Bowman ED, Vidal O, Sage J, Neal J, Ryan BM. Relationship between anti-depressant use and lung cancer survival. Cancer Treatment and Research Communications. 10: 33-39. PMID 28944316 DOI: 10.1016/J.Ctarc.2017.01.001 |
0.327 |
|
| 2017 |
Guan Y, Xu D, Garfin PM, Ehmer U, Hurwitz M, Enns G, Michie S, Wu M, Zheng M, Nishimura T, Sage J, Peltz G. Human hepatic organoids for the analysis of human genetic diseases. Jci Insight. 2. PMID 28878125 DOI: 10.1172/Jci.Insight.94954 |
0.3 |
|
| 2017 |
Mello SS, Sinow C, Raj N, Mazur PK, Bieging-Rolett K, Broz DK, Imam JFC, Vogel H, Wood LD, Sage J, Hirose T, Nakagawa S, Rinn J, Attardi LD. Neat1 is a p53-inducible lincRNA essential for transformation suppression. Genes & Development. PMID 28698299 DOI: 10.1101/Gad.284661.116 |
0.784 |
|
| 2017 |
Li LX, Fan LX, Zhou JX, Grantham JJ, Calvet JP, Sage J, Li X. Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease. The Journal of Clinical Investigation. PMID 28604386 DOI: 10.1172/Jci90921 |
0.354 |
|
| 2017 |
Szczepny A, Rogers S, Jayasekara WSN, Park K, McCloy RA, Cochrane CR, Ganju V, Cooper WA, Sage J, Peacock CD, Cain JE, Burgess A, Watkins DN. The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer. Oncogene. PMID 28581526 DOI: 10.1038/Onc.2017.173 |
0.473 |
|
| 2017 |
Sen T, Tong P, Stewart CA, Cristea S, Valliani A, Shames DS, Redwood A, Fan Y, Li L, Glisson BS, Minna J, Sage J, Gibbons DL, Piwnica-Worms H, Heymach J, et al. CHK1 inhibition in small cell lung cancer produces single-agent activity in biomarker-defined disease subsets and combination activity with cisplatin or olaparib. Cancer Research. PMID 28490518 DOI: 10.1158/0008-5472.Can-16-3409 |
0.42 |
|
| 2017 |
Lim JS, Ibaseta A, Fischer MM, Cancilla B, O'Young G, Cristea S, Luca VC, Yang D, Jahchan NS, Hamard C, Antoine M, Wislez M, Kong C, Cain J, Liu YW, ... ... Sage J, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. PMID 28489825 DOI: 10.1038/Nature22323 |
0.468 |
|
| 2017 |
Arand J, Sage J. G1 cyclins protect pluripotency. Nature Cell Biology. 19: 149-150. PMID 28248303 DOI: 10.1038/Ncb3480 |
0.354 |
|
| 2017 |
Vallejo A, Perurena N, Guruceaga E, Mazur PK, Martinez-Canarias S, Zandueta C, Valencia K, Arricibita A, Gwinn D, Sayles LC, Chuang CH, Guembe L, Bailey P, Chang DK, Biankin A, ... ... Sage J, et al. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nature Communications. 8: 14294. PMID 28220783 DOI: 10.1038/Ncomms14294 |
0.723 |
|
| 2017 |
Gardner EE, Lok BH, Schneeberger VE, Desmeules P, Miles LA, Arnold PK, Ni A, Khodos I, de Stanchina E, Nguyen T, Sage J, Campbell JE, Ribich S, Rekhtman N, Dowlati A, et al. Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis. Cancer Cell. 31: 286-299. PMID 28196596 DOI: 10.1016/J.Ccell.2017.01.006 |
0.449 |
|
| 2017 |
Sen T, Chen L, Rodriguez BL, Yang Y, Fan YH, Stewart CA, Glisson B, Piwnica-Worms H, Sage J, Heymach JV, Gibbons DL, Byers LA. Abstract B72: Combining immune checkpoint inhibition and DNA damage repair (DDR) targeted therapy in small cell lung cancer (SCLC) Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-B72 |
0.346 |
|
| 2016 |
Mazur PK, Gozani O, Sage J, Reynoird N. Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase. Translational Cancer Research. 5: 330-333. PMID 30713830 DOI: 10.21037/Tcr.2016.06.26 |
0.641 |
|
| 2016 |
Hubner EK, Lechler C, Kohnke-Ertel B, Zmoos AF, Sage J, Schmid RM, Ehmer U. An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes. The Journal of Gene Medicine. PMID 28009940 DOI: 10.1002/Jgm.2940 |
0.321 |
|
| 2016 |
Lázaro S, Pérez-Crespo M, Belén Enguita A, Hernández P, Martínez-Palacio J, Oteo M, Sage J, Paramio JM, Santos M. Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation. Oncotarget. PMID 27966456 DOI: 10.18632/Oncotarget.13875 |
0.427 |
|
| 2016 |
Hsu J, Sage J. Novel Functions for the Transcription Factor E2F4 in Development and Disease. Cell Cycle (Georgetown, Tex.). 0. PMID 27753528 DOI: 10.1080/15384101.2016.1234551 |
0.409 |
|
| 2016 |
Flores NM, Oviedo NJ, Sage J. ESSENTIAL ROLE FOR THE PLANARIAN INTESTINAL GATA TRANSCRIPTION FACTOR IN STEM CELLS AND REGENERATION. Developmental Biology. PMID 27542689 DOI: 10.1016/J.Ydbio.2016.08.015 |
0.349 |
|
| 2016 |
Denny SK, Yang D, Chuang CH, Brady JJ, Lim JS, Grüner BM, Chiou SH, Schep AN, Baral J, Hamard C, Antoine M, Wislez M, Kong CS, Connolly AJ, Park KS, ... Sage J, et al. Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility. Cell. PMID 27374332 DOI: 10.1016/J.Cell.2016.05.052 |
0.453 |
|
| 2016 |
Jahchan NS, Lim JS, Bola B, Morris K, Seitz G, Tran KQ, Xu L, Trapani F, Morrow CJ, Cristea S, Coles GL, Yang D, Vaka D, Kareta MS, George J, ... ... Sage J, et al. Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer. Cell Reports. PMID 27373157 DOI: 10.1016/J.Celrep.2016.06.021 |
0.719 |
|
| 2016 |
Weiskopf K, Jahchan NS, Schnorr PJ, Cristea S, Ring AM, Maute RL, Volkmer AK, Volkmer JP, Liu J, Lim JS, Yang D, Seitz G, Nguyen T, Wu D, Jude K, ... ... Sage J, et al. CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. The Journal of Clinical Investigation. PMID 27294525 DOI: 10.1172/Jci81603 |
0.344 |
|
| 2016 |
Cristea S, Sage J. Is the Canonical RAF/MEK/ERK Signaling Pathway a Therapeutic Target in SCLC? Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 27133774 DOI: 10.1016/J.Jtho.2016.04.018 |
0.443 |
|
| 2016 |
Krampitz GW, George BM, Willingham SB, Volkmer JP, Weiskopf K, Jahchan N, Newman AM, Sahoo D, Zemek AJ, Yanovsky RL, Nguyen JK, Schnorr PJ, Mazur PK, Sage J, Longacre TA, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035983 DOI: 10.1073/Pnas.1600007113 |
0.71 |
|
| 2016 |
Reynoird N, Mazur PK, Stellfeld T, Flores NM, Lofgren SM, Carlson SM, Brambilla E, Hainaut P, Kaznowska EB, Arrowsmith CH, Khatri P, Stresemann C, Gozani O, Sage J. Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer. Genes & Development. PMID 26988419 DOI: 10.1101/Gad.275529.115 |
0.711 |
|
| 2016 |
Garfin PM, Nguyen T, Sage J. Loss of Pten Disrupts the Thymic Epithelium and Alters Thymic Function. Plos One. 11: e0149430. PMID 26914657 DOI: 10.1371/Journal.Pone.0149430 |
0.366 |
|
| 2016 |
Bunn PA, Minna J, Augustyn A, Gazdar A, Ouadah Y, Krasnow MA, Berns A, Brambilla E, Rekhtman N, Massion PP, Niederst M, Peifer M, Yokota J, Govindan R, Poirier J, ... ... Sage J, et al. Small Cell Lung Cancer: Can recent advances in biology and molecular biology be translated into improved outcomes? Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26829312 DOI: 10.1016/J.Jtho.2016.01.012 |
0.366 |
|
| 2016 |
Lim JS, Ibaseta A, Yang D, Jahchan NS, Sage J. Abstract A37: Tumor heterogeneity in SCLC: A role for endogenous Notch signaling Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-A37 |
0.485 |
|
| 2016 |
Sen T, Tong P, Stewart CA, Cristea S, Hong-Fan Y, Glisson BS, Gibbons DL, Sage J, Wang J, Byers LA. Abstract PR10: Exploiting the G2-M cell cycle checkpoint dependency in small cell lung cancer (SCLC) using pharmacological inhibitors of CHK1 and WEE1 Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Pr10 |
0.475 |
|
| 2016 |
Kareta MS, O'Brien M, Wernig M, Sage J. Abstract PR06: Sox2 functions as a critical oncogene in Rb loss initiated tumors Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Pr06 |
0.447 |
|
| 2016 |
Mazur PK, Reynoird N, Stellfeld T, Flores NM, Lofgren SM, Carlson SM, Brambilla E, Hainaut P, Kaznowska EB, Arrowsmith CH, Khatri P, Stresemann C, Gozani O, Sage J. Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A44 |
0.651 |
|
| 2016 |
Vallejo A, Perurena N, Guruceaga E, Mazur PK, Martinez-Canarias S, Zandueta C, Gwinn D, Sayles LC, Chuang C, Andersen JB, Bozec A, Sweet-Cordero A, Sage J, Lecanda F, Vicent S. An integrative cross-tumors approach identifies FOSL1 as an oncogene dependency in KRAS-driven lung cancer Journal of Thoracic Oncology. 11: S51. DOI: 10.1016/J.Jtho.2015.12.084 |
0.667 |
|
| 2016 |
Kim D, Dunn CT, Sage J, Park K. Validation of L-Myc as a viable therapeutic target in small cell lung cancer Journal of Thoracic Oncology. 11: S28-S29. DOI: 10.1016/J.Jtho.2015.12.047 |
0.467 |
|
| 2015 |
Mazur PK, Sage J. Pancreatic cancer takes its Toll. The Journal of Experimental Medicine. 212: 1988. PMID 26573583 DOI: 10.1084/Jem.21212Insight1 |
0.657 |
|
| 2015 |
Kareta MS, Sage J, Wernig M. Crosstalk between stem cell and cell cycle machineries. Current Opinion in Cell Biology. 37: 68-74. PMID 26520682 DOI: 10.1016/J.Ceb.2015.10.001 |
0.364 |
|
| 2015 |
Ehmer U, Sage J. Control of proliferation and cancer growth by the Hippo signaling pathway. Molecular Cancer Research : McR. PMID 26432795 DOI: 10.1158/1541-7786.Mcr-15-0305 |
0.438 |
|
| 2015 |
Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, ... ... Sage J, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nature Medicine. PMID 26390243 DOI: 10.1038/Nm.3952 |
0.778 |
|
| 2015 |
George J, Lim JS, Jang SJ, Cun Y, Ozretić L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, ... ... Sage J, et al. Comprehensive genomic profiles of small cell lung cancer. Nature. 524: 47-53. PMID 26168399 DOI: 10.1038/Nature14664 |
0.453 |
|
| 2015 |
Gazdar AF, Savage TK, Johnson JE, Berns A, Sage J, Linnoila RI, MacPherson D, McFadden DG, Farago A, Jacks T, Travis WD, Brambilla E. The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 553-64. PMID 25675280 DOI: 10.1097/Jto.0000000000000459 |
0.61 |
|
| 2015 |
Kareta MS, Gorges LL, Hafeez S, Benayoun BA, Marro S, Zmoos AF, Cecchini MJ, Spacek D, Batista LF, O'Brien M, Ng YH, Ang CE, Vaka D, Artandi SE, Dick FA, ... ... Sage J, et al. Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis. Cell Stem Cell. 16: 39-50. PMID 25467916 DOI: 10.1016/J.Stem.2014.10.019 |
0.463 |
|
| 2015 |
Xu L, Hazard FK, Zmoos AF, Jahchan N, Chaib H, Garfin PM, Rangaswami A, Snyder MP, Sage J. Genomic analysis of fibrolamellar hepatocellular carcinoma. Human Molecular Genetics. 24: 50-63. PMID 25122662 DOI: 10.1093/Hmg/Ddu418 |
0.394 |
|
| 2015 |
Reynoird N, Mazur P, Sage J, Gozani O. SMYD3 links lysine methylation of MAP3K2 to ras-driven lung cancer European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa4256 |
0.693 |
|
| 2015 |
Mazur PK, Reynoird N, Khatri P, Butte AJ, Wilkinson A, Garcia B, Liu S, Vermeulen M, Jansen PWTC, Tummino PJ, Kruger RG, Aller GSV, Barbash O, Huddleston M, Gozani O, ... Sage J, et al. Abstract A23: SMYD3 links methylation of MAP3K2 to Ras-driven tumors Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A23 |
0.707 |
|
| 2015 |
Zingone A, Brown D, Bowman E, Vidal O, Neal J, Sage J, Ryan BM. Abstract LB-182: Improved survival among lung cancer patients taking antidepressants Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-182 |
0.395 |
|
| 2015 |
George J, Lim JS, Peifer M, Sage J, Thomas R. Abstract LB-168: Comprehensive genomic characterization of small cell lung cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-168 |
0.47 |
|
| 2015 |
Lechler C, Hubner E, Kohnke-Ertel B, Sage J, Schmid R, Ehmer U. Metastasis development in a novel mouse model of advanced liver cancer Zeitschrift FüR Gastroenterologie. 53. DOI: 10.1055/S-0034-1397184 |
0.34 |
|
| 2015 |
Krampitz GW, Willingham SB, Volkmer JP, Weiskopf KA, George BM, Sage J, Visser BC, Poultsides GA, Norton JA, Weissman IL. Identification of Tumorigenic Cells and Therapeutic Targets in Pancreatic Neuroendocrine Cancers Journal of the American College of Surgeons. 221: S59-S60. DOI: 10.1016/J.Jamcollsurg.2015.07.130 |
0.403 |
|
| 2014 |
Bremner R, Sage J. Cancer: The origin of human retinoblastoma. Nature. 514: 312-3. PMID 25252972 DOI: 10.1038/Nature13748 |
0.447 |
|
| 2014 |
Santos M, Martínez-Fernández M, Dueñas M, García-Escudero R, Alfaya B, Villacampa F, Saiz-Ladera C, Costa C, Oteo M, Duarte J, Martínez V, Gómez-Rodriguez MJ, Martín ML, Fernández M, Viatour P, ... ... Sage J, et al. In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer. Cancer Research. 74: 6565-77. PMID 25252918 DOI: 10.1158/0008-5472.Can-14-1218 |
0.47 |
|
| 2014 |
Ehmer U, Zmoos AF, Auerbach RK, Vaka D, Butte AJ, Kay MA, Sage J. Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo. Cell Reports. 8: 371-81. PMID 25017070 DOI: 10.1016/J.Celrep.2014.06.025 |
0.432 |
|
| 2014 |
Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, ... Sage J, et al. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 510: 283-7. PMID 24847881 DOI: 10.1038/Nature13320 |
0.688 |
|
| 2014 |
Ntziachristos P, Lim JS, Sage J, Aifantis I. From fly wings to targeted cancer therapies: a centennial for notch signaling. Cancer Cell. 25: 318-34. PMID 24651013 DOI: 10.1016/J.Ccr.2014.02.018 |
0.434 |
|
| 2014 |
Gocke CB, Wang Q, McMillan R, Penchev V, Sage J, Khavari PA, Matsui W. Inhibiting Oncogenic RAS in Multiple Myeloma By Targeting Scaffold-ERK Interactions Blood. 124: 2089-2089. DOI: 10.1182/Blood.V124.21.2089.2089 |
0.36 |
|
| 2014 |
Garfin PM, Min D, Weinber KI, Sage J. Abstract B76: Manipulating tumor suppressors to improve thymus function following hematopoietic stem cell transplantation Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-B76 |
0.445 |
|
| 2014 |
Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos A, Vaka D, Tran KQt, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, ... ... Sage J, et al. Abstract 4610: A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors Cancer Research. 74: 4610-4610. DOI: 10.1158/1538-7445.Am2014-4610 |
0.723 |
|
| 2014 |
Weiskopf K, Schnorr PJ, Jahchan N, Ring AM, Maute RL, Volkmer AK, Volkmer J, Garcia KC, Sage J, Weissman IL. Abstract 3629: Overcoming macrophage immunosuppression in small cell lung cancer with high-affinity SIRPa variants Cancer Research. 74: 3629-3629. DOI: 10.1158/1538-7445.Am2014-3629 |
0.37 |
|
| 2013 |
Rubin SM, Sage J. Defining a new vision for the retinoblastoma gene: report from the 3rd International Rb Meeting. Cell Division. 8: 13. PMID 24257515 DOI: 10.1186/1747-1028-8-13 |
0.446 |
|
| 2013 |
Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos AF, Vaka D, Tran KQ, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, ... ... Sage J, et al. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discovery. 3: 1364-77. PMID 24078773 DOI: 10.1158/2159-8290.Cd-13-0183 |
0.716 |
|
| 2013 |
Garfin PM, Min D, Bryson JL, Serwold T, Edris B, Blackburn CC, Richie ER, Weinberg KI, Manley NR, Sage J, Viatour P. Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. The Journal of Experimental Medicine. 210: 1087-97. PMID 23669396 DOI: 10.1084/Jem.20121716 |
0.369 |
|
| 2013 |
Attardi LD, Sage J. RB goes mitochondrial Genes and Development. 27: 975-979. PMID 23651852 DOI: 10.1101/Gad.219451.113 |
0.664 |
|
| 2013 |
Jameson KL, Mazur PK, Zehnder AM, Zhang J, Zarnegar B, Sage J, Khavari PA. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors. Nature Medicine. 19: 626-30. PMID 23603816 DOI: 10.1038/Nm.3165 |
0.68 |
|
| 2012 |
Conklin JF, Baker J, Sage J. The RB family is required for the self-renewal and survival of human embryonic stem cells. Nature Communications. 3: 1244. PMID 23212373 DOI: 10.1038/Ncomms2254 |
0.398 |
|
| 2012 |
Shin MK, Sage J, Lambert PF. Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer. Cancer Research. 72: 5418-27. PMID 22942253 DOI: 10.1158/0008-5472.Can-12-2083 |
0.331 |
|
| 2012 |
Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, ... ... Sage J, et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nature Genetics. 44: 1104-10. PMID 22941188 DOI: 10.1038/Ng.2396 |
0.407 |
|
| 2012 |
Sage J. The retinoblastoma tumor suppressor and stem cell biology. Genes & Development. 26: 1409-20. PMID 22751497 DOI: 10.1101/Gad.193730.112 |
0.398 |
|
| 2012 |
Van Aller GS, Reynoird N, Barbash O, Huddleston M, Liu S, Zmoos AF, McDevitt P, Sinnamon R, Le B, Mas G, Annan R, Sage J, Garcia BA, Tummino PJ, Gozani O, et al. Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Epigenetics. 7: 340-3. PMID 22419068 DOI: 10.4161/Epi.19506 |
0.363 |
|
| 2012 |
Sage J, Cleary ML. Genomics: The path to retinoblastoma. Nature. 481: 269-70. PMID 22258599 DOI: 10.1038/481269A |
0.405 |
|
| 2012 |
Garfin PM, Viatour P, Min D, Bryson J, Weinberg KI, Manley NR, Sage J. RB Controls Size, Cellularity, and T Cell Output of the Mouse Thymus Blood. 120: 835-835. DOI: 10.1182/Blood.V120.21.835.835 |
0.423 |
|
| 2012 |
Mazur PK, Lubeseder-Martellato C, Grüner BM, Sipos B, Angelis MHd, Sage J, Schmid RM, Siveke JT. Abstract A55: Dual role of the Notch ligand Delta-1 in pancreatic carcinogenesis and metastasis. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A55 |
0.745 |
|
| 2012 |
Sage J, Attardi L, van Dyke T. Roles of p53 and pRB tumor suppressor networks in human cancer: Insight from studies in the engineered mouse Genetically Engineered Mice For Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing. 293-308. DOI: 10.1007/978-0-387-69805-2_14 |
0.606 |
|
| 2011 |
Chen H, Gu X, Liu Y, Wang J, Wirt SE, Bottino R, Schorle H, Sage J, Kim SK. PDGF signalling controls age-dependent proliferation in pancreatic β-cells. Nature. 478: 349-55. PMID 21993628 DOI: 10.1038/Nature10502 |
0.316 |
|
| 2011 |
Park KS, Martelotto LG, Peifer M, Sos ML, Karnezis AN, Mahjoub MR, Bernard K, Conklin JF, Szczepny A, Yuan J, Guo R, Ospina B, Falzon J, Bennett S, Brown TJ, ... ... Sage J, et al. A crucial requirement for Hedgehog signaling in small cell lung cancer. Nature Medicine. 17: 1504-8. PMID 21983857 DOI: 10.1038/Nm.2473 |
0.455 |
|
| 2011 |
Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Kelly-Spratt K, Wong CH, Zhang Q, Chin A, Park KS, Goodman G, Gazdar AF, Sage J, Dinulescu DM, Kucherlapati R, et al. Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell. 20: 289-99. PMID 21907921 DOI: 10.1016/J.Ccr.2011.08.007 |
0.544 |
|
| 2011 |
Viatour P, Sage J. Newly identified aspects of tumor suppression by RB. Disease Models & Mechanisms. 4: 581-5. PMID 21878458 DOI: 10.1242/Dmm.008060 |
0.472 |
|
| 2011 |
Viatour P, Ehmer U, Saddic LA, Dorrell C, Andersen JB, Lin C, Zmoos AF, Mazur PK, Schaffer BE, Ostermeier A, Vogel H, Sylvester KG, Thorgeirsson SS, Grompe M, Sage J. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. The Journal of Experimental Medicine. 208: 1963-76. PMID 21875955 DOI: 10.1084/Jem.20110198 |
0.674 |
|
| 2011 |
McEvoy J, Flores-Otero J, Zhang J, Nemeth K, Brennan R, Bradley C, Krafcik F, Rodriguez-Galindo C, Wilson M, Xiong S, Lozano G, Sage J, Fu L, Louhibi L, Trimarchi J, et al. Coexpression of normally incompatible developmental pathways in retinoblastoma genesis. Cancer Cell. 20: 260-75. PMID 21840489 DOI: 10.1016/J.Ccr.2011.07.005 |
0.425 |
|
| 2011 |
Park KS, Liang MC, Raiser DM, Zamponi R, Roach RR, Curtis SJ, Walton Z, Schaffer BE, Roake CM, Zmoos AF, Kriegel C, Wong KK, Sage J, Kim CF. Characterization of the cell of origin for small cell lung cancer. Cell Cycle (Georgetown, Tex.). 10: 2806-15. PMID 21822053 DOI: 10.4161/Cc.10.16.17012 |
0.687 |
|
| 2011 |
Redwood AB, Perkins SM, Vanderwaal RP, Feng Z, Biehl KJ, Gonzalez-Suarez I, Morgado-Palacin L, Shi W, Sage J, Roti-Roti JL, Stewart CL, Zhang J, Gonzalo S. A dual role for A-type lamins in DNA double-strand break repair. Cell Cycle (Georgetown, Tex.). 10: 2549-60. PMID 21701264 DOI: 10.4161/Cc.10.15.16531 |
0.354 |
|
| 2011 |
Manley NR, Richie ER, Blackburn CC, Condie BG, Sage J. Structure and function of the thymic microenvironment. Frontiers in Bioscience (Landmark Edition). 16: 2461-77. PMID 21622189 DOI: 10.2741/3866 |
0.31 |
|
| 2011 |
Saddic LA, Wirt S, Vogel H, Felsher DW, Sage J. Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma. Plos One. 6: e19758. PMID 21573126 DOI: 10.1371/Journal.Pone.0019758 |
0.435 |
|
| 2011 |
Bourgo RJ, Ehmer U, Sage J, Knudsen ES. RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo. Molecular Biology of the Cell. 22: 931-9. PMID 21289097 DOI: 10.1091/Mbc.E10-11-0895 |
0.355 |
|
| 2011 |
Mazur PK, Lubeseder-Martellato C, Grüner BM, Kaznowska E, Sipos B, Angelis MHd, Schmid RM, Sage J, Siveke JT. Abstract PR16: Important bidirectional function in the Notch-Delta signaling in pancreatic carcinogenesis and metastasis Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-Pr16 |
0.754 |
|
| 2011 |
Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Sage J, Kemp CJ, Varmus HE, Hanash SM. Abstract 3166: Lung cancer bio-signatures in plasma based on the analysis of mouse models Cancer Research. 71: 3166-3166. DOI: 10.1158/1538-7445.Am2011-3166 |
0.551 |
|
| 2011 |
Shin MK, Pitot HC, Sage J, Lambert PF. Abstract 2100: Role of pocket proteins in HPV-associated head and neck squamous cell carcinomas Cancer Research. 71: 2100-2100. DOI: 10.1158/1538-7445.Am2011-2100 |
0.307 |
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| 2010 |
Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, Viatour P, Vogel H, Chang HY, Meissner A, Sage J. G1 arrest and differentiation can occur independently of Rb family function. The Journal of Cell Biology. 191: 809-25. PMID 21059851 DOI: 10.1083/Jcb.201003048 |
0.399 |
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| 2010 |
Saddic LA, West LE, Aslanian A, Yates JR, Rubin SM, Gozani O, Sage J. Methylation of the retinoblastoma tumor suppressor by SMYD2. The Journal of Biological Chemistry. 285: 37733-40. PMID 20870719 DOI: 10.1074/Jbc.M110.137612 |
0.412 |
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| 2010 |
Pajcini KV, Corbel SY, Sage J, Pomerantz JH, Blau HM. Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle. Cell Stem Cell. 7: 198-213. PMID 20682446 DOI: 10.1016/J.Stem.2010.05.022 |
0.331 |
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| 2010 |
Burkhart DL, Wirt SE, Zmoos AF, Kareta MS, Sage J. Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions. Plos Genetics. 6: e1001003. PMID 20585628 DOI: 10.1371/Journal.Pgen.1001003 |
0.784 |
|
| 2010 |
Sage J, Straight AF. RB's original CIN? Genes & Development. 24: 1329-33. PMID 20551167 DOI: 10.1101/Gad.1948010 |
0.373 |
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| 2010 |
Schaffer BE, Park KS, Yiu G, Conklin JF, Lin C, Burkhart DL, Karnezis AN, Sweet-Cordero EA, Sage J. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer Research. 70: 3877-83. PMID 20406986 DOI: 10.1158/0008-5472.CAN-09-4228 |
0.775 |
|
| 2010 |
Burkhart DL, Sage J. Complex transcriptional regulatory networks around the retinoblastoma tumor suppressor gene Cell Cycle. 9: 1663-1664. PMID 20404509 DOI: 10.4161/Cc.9.9.11593 |
0.733 |
|
| 2010 |
Wirt SE, Sage J. p107 in the public eye: an Rb understudy and more. Cell Division. 5: 9. PMID 20359370 DOI: 10.1186/1747-1028-5-9 |
0.442 |
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| 2010 |
Burkhart DL, Ngai LK, Roake CM, Viatour P, Thangavel C, Ho VM, Knudsen ES, Sage J. Regulation of RB transcription in vivo by RB family members. Molecular and Cellular Biology. 30: 1729-45. PMID 20100864 DOI: 10.1128/Mcb.00952-09 |
0.794 |
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| 2010 |
Wirt SE, Sage J. P107 in the public eye: An Rb understudy and more Cell Division. 5. DOI: 10.1186/1747-1028-5-9 |
0.332 |
|
| 2010 |
Park K, Sage J. Abstract 5755: Molecular mechanisms of small cell lung carcinoma development using preclinical mouse models Cancer Research. 70: 5755-5755. DOI: 10.1158/1538-7445.Am10-5755 |
0.522 |
|
| 2009 |
Conklin JF, Sage J. Keeping an eye on retinoblastoma control of human embryonic stem cells Journal of Cellular Biochemistry. 108: 1023-1030. PMID 19760644 DOI: 10.1002/Jcb.22342 |
0.386 |
|
| 2009 |
Gonzalez-Suarez I, Redwood AB, Perkins SM, Vermolen B, Lichtensztejin D, Grotsky DA, Morgado-Palacin L, Gapud EJ, Sleckman BP, Sullivan T, Sage J, Stewart CL, Mai S, Gonzalo S. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. The Embo Journal. 28: 2414-27. PMID 19629036 DOI: 10.1038/Emboj.2009.196 |
0.311 |
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| 2009 |
Lin PS, McPherson LA, Chen AY, Sage J, Ford JM. The role of the retinoblastoma/E2F1 tumor suppressor pathway in the lesion recognition step of nucleotide excision repair Dna Repair. 8: 795-802. PMID 19376752 DOI: 10.1016/J.Dnarep.2009.03.003 |
0.419 |
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| 2009 |
Ho VM, Schaffer BE, Karnezis AN, Park KS, Sage J. The retinoblastoma gene Rb and its family member p130 suppress lung adenocarcinoma induced by oncogenic K-Ras. Oncogene. 28: 1393-9. PMID 19151761 DOI: 10.1038/Onc.2008.491 |
0.444 |
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| 2008 |
Viatour P, Somervaille TC, Venkatasubrahmanyam S, Kogan S, McLaughlin ME, Weissman IL, Butte AJ, Passegué E, Sage J. Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell. 3: 416-28. PMID 18940733 DOI: 10.1016/J.Stem.2008.07.009 |
0.403 |
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| 2008 |
Burkhart DL, Viatour P, Ho VM, Sage J. GFP reporter mice for the retinoblastoma-related cell cycle regulator p107. Cell Cycle (Georgetown, Tex.). 7: 2544-52. PMID 18719374 DOI: 10.4161/Cc.7.16.6441 |
0.774 |
|
| 2008 |
Burkhart DL, Sage J. Cellular mechanisms of tumour suppression by the retinoblastoma gene Nature Reviews Cancer. 8: 671-682. PMID 18650841 DOI: 10.1038/Nrc2399 |
0.77 |
|
| 2007 |
Kotake Y, Cao R, Viatour P, Sage J, Zhang Y, Xiong Y. pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene. Genes & Development. 21: 49-54. PMID 17210787 DOI: 10.1101/Gad.1499407 |
0.417 |
|
| 2007 |
Sage J. Hope in sight for retinoblastoma. Nature Medicine. 13: 30-1. PMID 17206131 DOI: 10.1038/Nm0107-30 |
0.379 |
|
| 2006 |
Haigis K, Sage J, Glickman J, Shafer S, Jacks T. The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium. The Journal of Biological Chemistry. 281: 638-47. PMID 16258171 DOI: 10.1074/Jbc.M509053200 |
0.755 |
|
| 2005 |
Sebastian T, Malik R, Thomas S, Sage J, Johnson PF. C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence. The Embo Journal. 24: 3301-12. PMID 16107878 DOI: 10.1038/Sj.Emboj.7600789 |
0.399 |
|
| 2005 |
Sage J. Making young tumors old: a new weapon against cancer? Science of Aging Knowledge Environment : Sage Ke. 2005: pe25. PMID 16107660 DOI: 10.1126/Sageke.2005.33.Pe25 |
0.428 |
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| 2004 |
MacPherson D, Sage J, Kim T, Ho D, McLaughlin ME, Jacks T. Cell type-specific effects of Rb deletion in the murine retina. Genes & Development. 18: 1681-94. PMID 15231717 DOI: 10.1101/Gad.1203304 |
0.64 |
|
| 2004 |
Sage J. Cyclin C makes an entry into the cell cycle. Developmental Cell. 6: 607-8. PMID 15130482 DOI: 10.1016/S1534-5807(04)00137-6 |
0.372 |
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| 2004 |
Mayhew CN, Perkin LM, Zhang X, Sage J, Jacks T, Knudsen ES. Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents. Oncogene. 23: 4107-20. PMID 15064736 DOI: 10.1038/Sj.Onc.1207503 |
0.68 |
|
| 2004 |
Bosco EE, Mayhew CN, Hennigan RF, Sage J, Jacks T, Knudsen ES. RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult Nucleic Acids Research. 32: 25-34. PMID 14704340 DOI: 10.1093/Nar/Gkg919 |
0.623 |
|
| 2003 |
Balsitis SJ, Sage J, Duensing S, Münger K, Jacks T, Lambert PF. Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Molecular and Cellular Biology. 23: 9094-103. PMID 14645521 DOI: 10.1128/Mcb.23.24.9094-9103.2003 |
0.625 |
|
| 2003 |
Ihrie RA, Reczek E, Horner JS, Khachatrian L, Sage J, Jacks T, Attardi LD. Perp Is a Mediator of p53-Dependent Apoptosis in Diverse Cell Types Current Biology. 13: 1985-1990. PMID 14614825 DOI: 10.1016/J.Cub.2003.10.055 |
0.752 |
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| 2003 |
Sage J, Miller AL, Pérez-Mancera PA, Wysocki JM, Jacks T. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature. 424: 223-8. PMID 12853964 DOI: 10.1038/Nature01764 |
0.686 |
|
| 2003 |
MacPherson D, Sage J, Crowley D, Trumpp A, Bronson RT, Jacks T. Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system Molecular and Cellular Biology. 23: 1044-1053. PMID 12529408 DOI: 10.1128/Mcb.23.3.1044-1053.2003 |
0.632 |
|
| 2002 |
Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps MP, Rose DW, Rosenfeld MG, Glass CK. An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 109: 169-80. PMID 12007404 DOI: 10.1016/S0092-8674(02)00714-6 |
0.656 |
|
| 2002 |
de Vries A, Flores ER, Miranda B, Hsieh HM, van Oostrom CT, Sage J, Jacks T. Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function. Proceedings of the National Academy of Sciences of the United States of America. 99: 2948-53. PMID 11867759 DOI: 10.1073/Pnas.052713099 |
0.677 |
|
| 2000 |
Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, Jacks T. Targeted disruption of the three Rb-related genes leads to loss of G1 control and immortalization Genes and Development. 14: 3037-3050. PMID 11114892 DOI: 10.1101/Gad.843200 |
0.795 |
|
| 2000 |
Lilienbaum A, Sage J, Mémet S, Rassoulzadegan M, Cuzin F, Israël A. NF-kappa B is developmentally regulated during spermatogenesis in mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 219: 333-40. PMID 11066090 DOI: 10.1002/1097-0177(2000)9999:9999<::Aid-Dvdy1064>3.0.Co;2-D |
0.315 |
|
| 2000 |
Zhang Y, Griffith EC, Sage J, Jacks T, Liu JO. Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1. Proceedings of the National Academy of Sciences of the United States of America. 97: 6427-32. PMID 10841547 DOI: 10.1073/Pnas.97.12.6427 |
0.692 |
|
| 1999 |
Sage J, Martin L, Meuwissen R, Heyting C, Cuzin F, Rassoulzadegan M. Temporal and spatial control of the Sycp1 gene transcription in the mouse meiosis: regulatory elements active in the male are not sufficient for expression in the female gonad Mechanisms of Development. 80: 29-39. PMID 10096061 DOI: 10.1016/S0925-4773(98)00191-9 |
0.312 |
|
| 1998 |
Sage J, Martin L, Rassoulzadegan M, Cuzin F. Germ cell-specific enhancer activity of a repeated element in a variable region of the mouse genome Gene. 221: 85-92. PMID 9852953 DOI: 10.1016/S0378-1119(98)00420-X |
0.338 |
|
| 1997 |
Grandjean V, Sage J, Ranc F, Cuzin F, Rassoulzadegan M. Stage-specific signals in germ line differentiation: control of Sertoli cell phagocytic activity by spermatogenic cells. Developmental Biology. 184: 165-174. PMID 9142992 DOI: 10.1006/Dbio.1997.8518 |
0.393 |
|
| 1996 |
Aperlo C, Boulukos KE, Sage J, Cuzin F, Pognonec P. Complete Sequencing of the Murine USF Gene and Comparison of Its Genomic Organization to That of mFIP/USF2 Genomics. 37: 337-344. PMID 8938446 DOI: 10.1006/Geno.1996.0568 |
0.331 |
|
| 1993 |
Rassoulzadegan M, Paquis-Flucklinger V, Bertino B, Sage J, Jasin M, Miyagawa K, Heyningen Vv, Besmer P, Cuzin F. Transmeiotic differentiation of male germ cells in culture Cell. 75: 997-1006. PMID 7504588 DOI: 10.1016/0092-8674(93)90543-Y |
0.418 |
|
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