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Wendy V. Gilbert - Publications

Affiliations: 
2008-2017 Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
 2017- Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
translational control of gene expression
Website:
https://medicine.yale.edu/profile/wendy-gilbert/
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Schaening-Burgos C, LeBlanc H, Fagre C, Li GW, Gilbert WV. RluA is the major mRNA pseudouridine synthase in Escherichia coli. Plos Genetics. 20: e1011100. PMID 39241085 DOI: 10.1371/journal.pgen.1011100  0.515
2024 Gilbert WV. Recent developments, opportunities, and challenges in the study of mRNA pseudouridylation. Rna (New York, N.Y.). PMID 38531650 DOI: 10.1261/rna.079975.124  0.487
2024 Lewis CJT, Xie L, Bhandarkar S, Jin D, Abdallah KS, Draycott AS, Chen Y, Thoreen CC, Gilbert WV. Quantitative profiling of human translation initiation reveals regulatory elements that potently affect endogenous and therapeutically modified mRNAs. Biorxiv : the Preprint Server For Biology. PMID 38463950 DOI: 10.1101/2024.02.28.582532  0.518
2024 Fagre C, Gilbert W. Beyond reader proteins: RNA binding proteins and RNA modifications in conversation to regulate gene expression. Wiley Interdisciplinary Reviews. Rna. 15: e1834. PMID 38444048 DOI: 10.1002/wrna.1834  0.33
2023 Draycott AS, Schaening-Burgos C, Rojas-Duran MF, Gilbert WV. D-Seq: Genome-wide detection of dihydrouridine modifications in RNA. Methods in Enzymology. 692: 3-22. PMID 37925185 DOI: 10.1016/bs.mie.2023.09.001  0.345
2023 Devarkar SC, Vetick M, Balaji S, Lomakin IB, Yang L, Jin D, Gilbert WV, Chen S, Xiong Y. Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses. Cell Reports. 42: 113156. PMID 37733586 DOI: 10.1016/j.celrep.2023.113156  0.304
2023 Gilbert WV, Nachtergaele S. mRNA Regulation by RNA Modifications. Annual Review of Biochemistry. PMID 37018844 DOI: 10.1146/annurev-biochem-052521-035949  0.517
2022 Lewis CJT, Niederer RO, Neupane R, Gilbert WV. Optimized protocol for quantifying 5' UTR-mediated translation initiation in S. cerevisiae using direct analysis of ribosome targeting. Star Protocols. 3: 101862. PMID 36595943 DOI: 10.1016/j.xpro.2022.101862  0.387
2022 Draycott AS, Schaening-Burgos C, Rojas-Duran MF, Wilson L, Schärfen L, Neugebauer KM, Nachtergaele S, Gilbert WV. Transcriptome-wide mapping reveals a diverse dihydrouridine landscape including mRNA. Plos Biology. 20: e3001622. PMID 35609439 DOI: 10.1371/journal.pbio.3001622  0.407
2022 Martinez NM, Su A, Burns MC, Nussbacher JK, Schaening C, Sathe S, Yeo GW, Gilbert WV. Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing. Molecular Cell. PMID 35051350 DOI: 10.1016/j.molcel.2021.12.023  0.584
2022 Niederer RO, Rojas-Duran MF, Zinshteyn B, Gilbert WV. Direct analysis of ribosome targeting illuminates thousand-fold regulation of translation initiation. Cell Systems. PMID 35041803 DOI: 10.1016/j.cels.2021.12.002  0.58
2021 Martinez NM, Schaening-Burgos C, Gilbert WV. Pseudouridine site assignment by high-throughput in vitro RNA pseudouridylation and sequencing. Methods in Enzymology. 658: 277-310. PMID 34517951 DOI: 10.1016/bs.mie.2021.06.026  0.34
2021 Wang YJ, Gilbert WV. Quantitative Comparisons of Translation Activity by Ribosome Profiling with Internal Standards. Methods in Molecular Biology (Clifton, N.J.). 2252: 127-149. PMID 33765273 DOI: 10.1007/978-1-0716-1150-0_5  0.373
2020 Borchardt EK, Martinez NM, Gilbert WV. Regulation and Function of RNA Pseudouridylation in Human Cells. Annual Review of Genetics. PMID 32870730 DOI: 10.1146/annurev-genet-112618-043830  0.308
2020 Wells JN, Buschauer R, Mackens-Kiani T, Best K, Kratzat H, Berninghausen O, Becker T, Gilbert W, Cheng J, Beckmann R. Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biology. 18: e3000780. PMID 32687489 DOI: 10.1371/Journal.Pbio.3000780  0.494
2020 Wells JN, Buschauer R, Mackens-Kiani T, Best K, Kratzat H, Berninghausen O, Becker T, Gilbert W, Cheng J, Beckmann R. Cryo-EM data collection, refinement, and validation statistics. Plos Biology. DOI: 10.1371/Journal.Pbio.3000780.S012  0.323
2019 Carlile TM, Martinez NM, Schaening C, Su A, Bell TA, Zinshteyn B, Gilbert WV. mRNA structure determines modification by pseudouridine synthase 1. Nature Chemical Biology. PMID 31477916 DOI: 10.1038/s41589-019-0353-z  0.487
2018 Martinez NM, Gilbert WV. Pre-mRNA modifications and their role in nuclear processing. Quantitative Biology (Beijing, China). 6: 210-227. PMID 30533247 DOI: 10.1007/s40484-018-0147-4  0.382
2018 Wang YJ, Vaidyanathan PP, Rojas-Duran MF, Udeshi ND, Bartoli KM, Carr SA, Gilbert WV. Lso2 is a conserved ribosome-bound protein required for translational recovery in yeast. Plos Biology. 16: e2005903. PMID 30208026 DOI: 10.1371/Journal.Pbio.2005903  0.55
2017 Zinshteyn B, Rojas Duran MF, Gilbert WV. Translation initiation factor eIF4G1 preferentially binds yeast transcript leaders containing conserved oligo-uridine motifs. Rna (New York, N.Y.). PMID 28546148 DOI: 10.1261/Rna.062059.117  0.668
2016 Thompson MK, Gilbert WV. mRNA length-sensing in eukaryotic translation: reconsidering the "closed loop" and its implications for translational control. Current Genetics. PMID 28028558 DOI: 10.1007/S00294-016-0674-3  0.676
2016 Cattie DJ, Richardson CE, Reddy KC, Ness-Cohn EM, Droste R, Thompson MK, Gilbert WV, Kim DH. Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans. Plos Genetics. 12: e1006326. PMID 27690135 DOI: 10.1371/Journal.Pgen.1006326  0.449
2016 Stanley SE, Gable DL, Wagner CL, Carlile TM, Hanumanthu VS, Podlevsky JD, Khalil SE, DeZern AE, Rojas-Duran MF, Applegate CD, Alder JK, Parry EM, Gilbert WV, Armanios M. Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema. Science Translational Medicine. 8: 351ra107. PMID 27510903 DOI: 10.1126/Scitranslmed.Aaf7837  0.357
2016 Gould GM, Paggi JM, Guo Y, Phizicky DV, Zinshteyn B, Wang ET, Gilbert WV, Gifford DK, Burge CB. Identification of new branch points and unconventional introns in Saccharomyces cerevisiae. Rna (New York, N.Y.). PMID 27473169 DOI: 10.1261/Rna.057216.116  0.527
2016 Gilbert WV, Bell TA, Schaening C. Messenger RNA modifications: Form, distribution, and function. Science (New York, N.Y.). 352: 1408-12. PMID 27313037 DOI: 10.1126/Science.Aad8711  0.479
2016 Thompson MK, Rojas-Duran MF, Gangaramani P, Gilbert WV. The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs. Elife. 5. PMID 27117520 DOI: 10.7554/Elife.11154  0.664
2016 Thompson MK, Rojas-Duran MF, Gangaramani P, Gilbert WV. Author response: The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs Elife. DOI: 10.7554/Elife.11154.033  0.653
2015 Carlile TM, Rojas-Duran MF, Gilbert WV. Transcriptome-Wide Identification of Pseudouridine Modifications Using Pseudo-seq. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 112: 4.25.1-4.25.24. PMID 26423590 DOI: 10.1002/0471142727.Mb0425S112  0.45
2015 Berchowitz LE, Kabachinski G, Walker MR, Carlile TM, Gilbert WV, Schwartz TU, Amon A. Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis. Cell. PMID 26411291 DOI: 10.1016/J.Cell.2015.08.060  0.455
2015 Carlile TM, Rojas-Duran MF, Gilbert WV. Pseudo-Seq: Genome-Wide Detection of Pseudouridine Modifications in RNA. Methods in Enzymology. 560: 219-45. PMID 26253973 DOI: 10.1016/Bs.Mie.2015.03.011  0.48
2015 Saha A, Mitchell JA, Nishida Y, Hildreth JE, Ariberre JA, Gilbert WV, Garfinkel DJ. A trans-dominant form of Gag restricts Ty1 retrotransposition and mediates copy number control. Journal of Virology. 89: 3922-38. PMID 25609815 DOI: 10.1128/Jvi.03060-14  0.325
2014 Carlile TM, Rojas-Duran MF, Zinshteyn B, Shin H, Bartoli KM, Gilbert WV. Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells. Nature. 515: 143-6. PMID 25192136 DOI: 10.1038/Nature13802  0.518
2014 Vaidyanathan PP, Zinshteyn B, Thompson MK, Gilbert WV. Protein kinase A regulates gene-specific translational adaptation in differentiating yeast. Rna (New York, N.Y.). 20: 912-22. PMID 24759091 DOI: 10.1261/Rna.044552.114  0.553
2013 Zinshteyn B, Gilbert WV. Loss of a conserved tRNA anticodon modification perturbs cellular signaling. Plos Genetics. 9: e1003675. PMID 23935536 DOI: 10.1371/Journal.Pgen.1003675  0.522
2013 Arribere JA, Gilbert WV. Roles for transcript leaders in translation and mRNA decay revealed by transcript leader sequencing. Genome Research. 23: 977-87. PMID 23580730 DOI: 10.1101/Gr.150342.112  0.637
2012 Rojas-Duran MF, Gilbert WV. Alternative transcription start site selection leads to large differences in translation activity in yeast. Rna (New York, N.Y.). 18: 2299-305. PMID 23105001 DOI: 10.1261/Rna.035865.112  0.655
2011 Arribere JA, Doudna JA, Gilbert WV. Reconsidering movement of eukaryotic mRNAs between polysomes and P bodies. Molecular Cell. 44: 745-58. PMID 22152478 DOI: 10.1016/J.Molcel.2011.09.019  0.675
2011 Gilbert WV. Functional specialization of ribosomes? Trends in Biochemical Sciences. 36: 127-32. PMID 21242088 DOI: 10.1016/J.Tibs.2010.12.002  0.613
2010 Gilbert WV. Alternative ways to think about cellular internal ribosome entry. The Journal of Biological Chemistry. 285: 29033-8. PMID 20576611 DOI: 10.1074/Jbc.R110.150532  0.657
2010 Clarkson BK, Gilbert WV, Doudna JA. Functional overlap between eIF4G isoforms in Saccharomyces cerevisiae. Plos One. 5: e9114. PMID 20161741 DOI: 10.1371/Journal.Pone.0009114  0.717
2009 Coyle SM, Gilbert WV, Doudna JA. Direct link between RACK1 function and localization at the ribosome in vivo. Molecular and Cellular Biology. 29: 1626-34. PMID 19114558 DOI: 10.1128/Mcb.01718-08  0.642
2007 Gilbert WV, Zhou K, Butler TK, Doudna JA. Cap-independent translation is required for starvation-induced differentiation in yeast. Science (New York, N.Y.). 317: 1224-7. PMID 17761883 DOI: 10.1126/Science.1144467  0.711
2004 Gilbert W, Guthrie C. The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA. Molecular Cell. 13: 201-12. PMID 14759366 DOI: 10.1016/S1097-2765(04)00030-9  0.76
2001 Gilbert W, Siebel CW, Guthrie C. Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. Rna (New York, N.Y.). 7: 302-13. PMID 11233987 DOI: 10.1017/S1355838201002369  0.644
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