| Year |
Citation |
Score |
| 2024 |
Cai L, Gao Y, DeBerardinis R, Chen T, Winslow M, Xiao G, Rudin C, Oliver T, Minna J, Xie Y. A Lung Cancer Mouse Model Database. Biorxiv : the Preprint Server For Biology. PMID 38464291 DOI: 10.1101/2024.02.28.582577 |
0.397 |
|
| 2024 |
Nabet BY, Hamidi H, Lee MC, Banchereau R, Morris S, Adler L, Gayevskiy V, Elhossiny AM, Srivastava MK, Patil NS, Smith KA, Jesudason R, Chan C, Chang PS, Fernandez M, ... ... Minna JD, et al. Immune heterogeneity in small-cell lung cancer and vulnerability to immune checkpoint blockade. Cancer Cell. PMID 38366589 DOI: 10.1016/j.ccell.2024.01.010 |
0.307 |
|
| 2024 |
Eglenen-Polat B, Kowash RR, Huang HC, Siteni S, Zhu M, Chen K, Bender ME, Mender I, Stastny V, Drapkin BJ, Raj P, Minna JD, Xu L, Shay JW, Akbay EA. A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer. Nature Communications. 15: 672. PMID 38253555 DOI: 10.1038/s41467-024-44861-8 |
0.339 |
|
| 2024 |
Kim C, Wang XD, Liu Z, Hao J, Wang S, Li P, Zi Z, Ding Q, Jang S, Kim J, Luo Y, Huffman KE, Pal Choudhuri S, Del Rio S, Cai L, ... ... Minna JD, et al. Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors. Science Advances. 10: eadh2579. PMID 38241363 DOI: 10.1126/sciadv.adh2579 |
0.355 |
|
| 2024 |
Chen H, Drapkin BJ, Minna JD. Proteomics: A new dimension to decode small cell lung cancer. Cell. 187: 14-16. PMID 38181738 DOI: 10.1016/j.cell.2023.11.042 |
0.433 |
|
| 2024 |
Ng J, Cai L, Girard L, Prall OWJ, Rajan N, Khoo C, Batrouney A, Byrne DJ, Boyd DK, Kersbergen AJ, Christie M, Minna JD, Burr ML, Sutherland KD. Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. OF1-OF13. PMID 38180245 DOI: 10.1158/1078-0432.CCR-23-2360 |
0.424 |
|
| 2023 |
Sunaga N, Kaira K, Shimizu K, Tanaka I, Miura Y, Nakazawa S, Ohtaki Y, Kawabata-Iwakawa R, Sato M, Girard L, Minna JD, Hisada T. The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β-catenin signaling in lung cancer. Thoracic Cancer. PMID 38014454 DOI: 10.1111/1759-7714.15169 |
0.357 |
|
| 2023 |
Zhu M, Kim J, Deng Q, Ricciuti B, Alessi JV, Eglenen-Polat B, Bender ME, Huang HC, Kowash RR, Cuevas I, Bennett ZT, Gao J, Minna JD, Castrillon DH, Awad MM, et al. Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden. Cancer Cell. PMID 37774698 DOI: 10.1016/j.ccell.2023.09.006 |
0.315 |
|
| 2023 |
Malchers F, Nogova L, van Attekum MH, Maas L, Brägelmann J, Bartenhagen C, Girard L, Bosco G, Dahmen I, Michels S, Weeden CE, Scheel AH, Meder L, Golfmann K, Schuldt P, ... ... Minna JD, et al. Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer. The Journal of Clinical Investigation. PMID 37606995 DOI: 10.1172/JCI170217 |
0.382 |
|
| 2023 |
Kawabe N, Matsuoka K, Komeda K, Muraki N, Takaba M, Togami Y, Ito Y, Yamada M, Sunaga N, Girard L, Minna JD, Cai L, Xie Y, Tanaka I, Morise M, et al. Silencing of induces epithelial‑to‑mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth. Oncology Letters. 26: 391. PMID 37600329 DOI: 10.3892/ol.2023.13977 |
0.452 |
|
| 2023 |
Martin-Vega A, Earnest S, Augustyn A, Wichaidit C, Gazdar A, Girard L, Peyton M, Kollipara RK, Minna JD, Johnson JE, Cobb MH. ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers. Biorxiv : the Preprint Server For Biology. PMID 37398419 DOI: 10.1101/2023.06.15.545148 |
0.414 |
|
| 2023 |
Kwok HH, Li H, Yang J, Deng J, Lee NC, Au TW, Sit AK, Hsin MK, Ma SK, Cheung LW, Girard L, Fujimoto J, Wistuba II, Gao B, Minna JD, et al. Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma. Cancer Communications (London, England). PMID 37272226 DOI: 10.1002/cac2.12449 |
0.326 |
|
| 2023 |
Cai L, DeBerardinis RJ, Xie Y, Minna JD, Xiao G. A Comparative Study of Neuroendocrine Heterogeneity in Small Cell Lung Cancer and Neuroblastoma. Molecular Cancer Research : McR. OF1-OF13. PMID 37255415 DOI: 10.1158/1541-7786.MCR-23-0002 |
0.432 |
|
| 2023 |
Cai L, DeBerardinis RJ, Xie Y, Minna JD, Xiao G. A comparative study of neuroendocrine heterogeneity in small cell lung cancer and neuroblastoma. Molecular Cancer Research : McR. PMID 37171983 DOI: 10.1158/1541-7786.MCR-23-0002 |
0.426 |
|
| 2023 |
Iyengar P, Gandhi AY, Granados J, Guo T, Gupta A, Yu J, Llano EM, Zhang F, Gao A, Kandathil A, Williams D, Gao B, Girard L, Malladi VS, Shelton JM, ... ... Minna JD, et al. Tumor loss-of-function mutations in STK11/LKB1 induce cachexia. Jci Insight. 8. PMID 37092555 DOI: 10.1172/jci.insight.165419 |
0.351 |
|
| 2023 |
Huffman KE, Li LS, Carstens R, Park H, Girard L, Avila K, Wei S, Kollipara R, Timmons B, Sudderth J, Bendris N, Kim J, Villalobos P, Fujimoto J, Schmid S, ... ... Minna JD, et al. Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers. Frontiers in Oncology. 13: 1025443. PMID 37035141 DOI: 10.3389/fonc.2023.1025443 |
0.435 |
|
| 2023 |
Kim J, Minna JD. Moving toward precision medicine with lung cancer organoids. Cell Reports. Medicine. 4: 100952. PMID 36812886 DOI: 10.1016/j.xcrm.2023.100952 |
0.335 |
|
| 2023 |
Wang S, Rong R, Yang DM, Fujimoto J, Bishop JA, Yan S, Cai L, Behrens C, Berry LD, Wilhelm C, Aisner D, Sholl L, Johnson BE, Kwiatkowski DJ, Wistuba II, ... ... Minna J, et al. Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer. The Journal of Clinical Investigation. 133. PMID 36647832 DOI: 10.1172/JCI160330 |
0.316 |
|
| 2022 |
Asaithamby A, Shay JW, Minna JD. Cellular senescence and lung cancer prognosis. Translational Lung Cancer Research. 11: 1982-1987. PMID 36386455 DOI: 10.21037/tlcr-22-678 |
0.41 |
|
| 2022 |
Bartolacci C, Andreani C, Vale G, Berto S, Melegari M, Crouch AC, Baluya DL, Kemble G, Hodges K, Starrett J, Politi K, Starnes SL, Lorenzini D, Raso MG, Solis Soto LM, ... ... Minna JD, et al. Author Correction: Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer. Nature Communications. 13: 4640. PMID 35941179 DOI: 10.1038/s41467-022-32459-x |
0.352 |
|
| 2022 |
Han JH, Kim YK, Kim H, Lee J, Oh MJ, Kim SB, Kim M, Kim KH, Yoon HJ, Lee MS, Minna JD, White MA, Kim HS. Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells. Cancer Communications (London, England). PMID 35838183 DOI: 10.1002/cac2.12332 |
0.325 |
|
| 2022 |
Voth Park J, Chandra R, Cai L, Ganguly D, Li H, Toombs JE, Girard L, Brekken RA, Minna JD. Tumor cells modulate macrophage phenotype in a novel in vitro co-culture model of the non-small cell lung cancer tumor microenvironment. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 35798240 DOI: 10.1016/j.jtho.2022.06.011 |
0.332 |
|
| 2022 |
Li H, Liu Z, Liu L, Zhang H, Han C, Girard L, Park H, Zhang A, Dong C, Ye J, Rayford A, Peyton M, Li X, Avila K, Cao X, ... ... Minna JD, et al. AXL targeting restores PD-1 blockade sensitivity of mutant NSCLC through expansion of TCF1 CD8 T cells. Cell Reports. Medicine. 3: 100554. PMID 35492873 DOI: 10.1016/j.xcrm.2022.100554 |
0.326 |
|
| 2022 |
Kim Y, Lee S, Cho S, Park J, Chae D, Park T, Minna JD, Kim HH. High-throughput functional evaluation of human cancer-associated mutations using base editors. Nature Biotechnology. PMID 35411116 DOI: 10.1038/s41587-022-01276-4 |
0.302 |
|
| 2022 |
Osborne JK, Minna JD. Lung Cancer Cell of Origin: Controversy and Clinical Translational Implications. Cancer Research. 82: 972-973. PMID 35288734 DOI: 10.1158/0008-5472.CAN-22-0301 |
0.404 |
|
| 2022 |
Shukla SP, Zhang H, Fang B, Minna JD, Gomika Udugamasooriya D. Unbiased peptoid cell screen identifies a peptoid targeting newly appeared cell surface vimentin on tumor transformed early lung cancer cells. Bioorganic & Medicinal Chemistry. 58: 116673. PMID 35189561 DOI: 10.1016/j.bmc.2022.116673 |
0.398 |
|
| 2021 |
Chandra R, Karalis JD, Liu C, Murimwa GZ, Voth Park J, Heid CA, Reznik SI, Huang E, Minna JD, Brekken RA. The Colorectal Cancer Tumor Microenvironment and Its Impact on Liver and Lung Metastasis. Cancers. 13. PMID 34944826 DOI: 10.3390/cancers13246206 |
0.349 |
|
| 2021 |
Rolfo C, Meshulami N, Russo A, Krammer F, Garcia-Sastre A, Mack PC, Gomez JE, Bhardwaj N, Benyounes A, Sirera R, Moore A, Rohs N, Henschke CI, Yankelevitz D, King J, ... ... Minna JD, et al. Lung Cancer and SARS-CoV-2 infection: Identifying important knowledge gaps for investigation. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 34774792 DOI: 10.1016/j.jtho.2021.11.001 |
0.37 |
|
| 2021 |
Cai L, Xiao G, Gerber D, Minna JD, Xie Y. Lung Cancer Computational Biology and Resources. Cold Spring Harbor Perspectives in Medicine. PMID 34751162 DOI: 10.1101/cshperspect.a038273 |
0.367 |
|
| 2021 |
Galan-Cobo A, Stellrecht CM, Yilmaz E, Yang C, Qian Y, Qu X, Akhter I, Ayres ML, Fan Y, Tong P, Diao L, Ding J, Giri U, Gudikote J, Nilsson M, ... ... Minna JD, et al. Enhanced vulnerability of LKB1-deficient NSCLC to disruption of ATP pools and redox homeostasis by 8-Cl-Ado. Molecular Cancer Research : McR. PMID 34654720 DOI: 10.1158/1541-7786.MCR-21-0448 |
0.351 |
|
| 2021 |
Pozo K, Kollipara RK, Kelenis DP, Rodarte KE, Ullrich MS, Zhang X, Minna JD, Johnson JE. ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer. Iscience. 24: 102953. PMID 34466783 DOI: 10.1016/j.isci.2021.102953 |
0.333 |
|
| 2021 |
Rashdan S, Iyengar P, Minna JD, Gerber DE. Narrative review: molecular and genetic profiling of oligometastatic non-small cell lung cancer. Translational Lung Cancer Research. 10: 3351-3368. PMID 34430372 DOI: 10.21037/tlcr-21-448 |
0.399 |
|
| 2021 |
von Itzstein MS, Drapkin BJ, Minna JD. How lung cancer cells change identity. Elife. 10. PMID 34346867 DOI: 10.7554/eLife.71610 |
0.399 |
|
| 2021 |
Stewart CA, Gay CM, Ramkumar K, Cargill KR, Cardnell RJ, Nilsson MB, Heeke S, Park EM, Kundu ST, Diao L, Wang Q, Shen L, Xi Y, Zhang B, Della Corte CM, ... ... Minna JD, et al. Lung cancer models reveal SARS-CoV-2-induced EMT contributes to COVID-19 pathophysiology. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 34274504 DOI: 10.1016/j.jtho.2021.07.002 |
0.351 |
|
| 2021 |
von Itzstein MS, Gerber DE, Minna JD. Contemporary Lung Cancer Screening and the Promise of Blood-Based Biomarkers. Cancer Research. 81: 3441-3443. PMID 34252039 DOI: 10.1158/0008-5472.CAN-21-0706 |
0.379 |
|
| 2021 |
Drapkin BJ, Minna JD. A rational targeted therapy for platinum-resistant small-cell lung cancer. Cancer Cell. 39: 453-456. PMID 33848475 DOI: 10.1016/j.ccell.2021.03.003 |
0.348 |
|
| 2021 |
Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, ... ... Minna JD, et al. Single-Cell Expression Landscape of SARS-CoV-2 Receptor and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients. Cancers. 13. PMID 33809063 DOI: 10.3390/cancers13061250 |
0.411 |
|
| 2021 |
Cai L, Liu H, Huang F, Fujimoto J, Girard L, Chen J, Li Y, Zhang YA, Deb D, Stastny V, Pozo K, Kuo CS, Jia G, Yang C, Zou W, ... ... Minna JD, et al. Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer. Communications Biology. 4: 314. PMID 33750914 DOI: 10.1038/s42003-021-01842-7 |
0.405 |
|
| 2021 |
Yuan G, Flores NM, Hausmann S, Lofgren SM, Kharchenko V, Angulo-Ibanez M, Sengupta D, Lu X, Czaban I, Azhibek D, Vicent S, Fischle W, Jaremko M, Fang B, Wistuba II, ... ... Minna JD, et al. Elevated NSD3 histone methylation activity drives squamous cell lung cancer. Nature. PMID 33536620 DOI: 10.1038/s41586-020-03170-y |
0.335 |
|
| 2021 |
Zhu M, Huang Y, Bender ME, Girard L, Kollipara R, Eglenen-Polat B, Naito Y, Savage TK, Huffman KE, Koyama S, Kumanogoh A, Minna JD, Johnson JE, Akbay EA. Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis. Cancer Research. PMID 33495232 DOI: 10.1158/0008-5472.CAN-20-2808 |
0.353 |
|
| 2021 |
Gay CM, Stewart CA, Park EM, Diao L, Groves SM, Heeke S, Nabet BY, Fujimoto J, Solis LM, Lu W, Xi Y, Cardnell RJ, Wang Q, Fabbri G, Cargill KR, ... ... Minna J, et al. Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities. Cancer Cell. PMID 33482121 DOI: 10.1016/j.ccell.2020.12.014 |
0.305 |
|
| 2021 |
Patel S, Herynk M, Cascone T, Saigal B, Nilsson M, Tran H, Ramachandran S, Minna J, Wistuba I, Heymach J. P71.02 Estrogen Promotes Resistance to Bevacizumab Treatment in Non-Small Cell Lung Cancer (NSCLC) Xenograft Models Journal of Thoracic Oncology. 16: S564-S565. DOI: 10.1016/J.JTHO.2021.01.1018 |
0.391 |
|
| 2020 |
Zhang X, Zhang R, Chen H, Wang L, Ren C, Pataer A, Wu S, Meng QH, Ha MJ, Morris J, Xi Y, Wang J, Zhang J, Gibbons DL, Heymach JV, ... ... Minna J, et al. KRT-232 and navitoclax enhance trametinib's anti-Cancer activity in non-small cell lung cancer patient-derived xenografts with KRAS mutations. American Journal of Cancer Research. 10: 4464-4475. PMID 33415011 |
0.355 |
|
| 2020 |
Thomas PL, Madubata CJ, Aldrich MC, Lee MM, Owonikoko TK, Minna JD, Rudin CM, Sage J, Lovly CM. A Call to Action: Dismantling Racial Injustices in Preclinical Research and Clinical Care of Black Patients Living with Small Cell Lung Cancer. Cancer Discovery. PMID 33318034 DOI: 10.1158/2159-8290.CD-20-1592 |
0.323 |
|
| 2020 |
Kim J, Lee HM, Cai F, Ko B, Yang C, Lieu EL, Muhammad N, Rhyne S, Li K, Haloul M, Gu W, Faubert B, Kaushik AK, Cai L, Kasiri S, ... ... Minna JD, et al. The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer. Nature Metabolism. PMID 33257855 DOI: 10.1038/s42255-020-00316-0 |
0.32 |
|
| 2020 |
Tlemsani C, Pongor L, Elloumi F, Girard L, Huffman KE, Roper N, Varma S, Luna A, Rajapakse VN, Sebastian R, Kohn KW, Krushkal J, Aladjem MI, Teicher BA, Meltzer PS, ... ... Minna JD, et al. SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures. Cell Reports. 33: 108296. PMID 33086069 DOI: 10.1016/j.celrep.2020.108296 |
0.409 |
|
| 2020 |
Huang F, Huffman K, Wang Z, Wang X, Li K, Cai F, Yang C, Cai L, Shih TS, Zacharias LG, Chung AS, Yang Q, Chalishazar MD, Ireland AS, Stewart CA, ... ... Minna J, et al. Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small cell lung cancer. The Journal of Clinical Investigation. PMID 33079728 DOI: 10.1172/JCI139929 |
0.314 |
|
| 2020 |
Sato M, Shay JW, Minna JD. Immortalized normal human lung epithelial cell models for studying lung cancer biology. Respiratory Investigation. PMID 32586780 DOI: 10.1016/J.Resinv.2020.04.005 |
0.418 |
|
| 2020 |
Stewart CA, Gay CM, Ramkumar K, Cargill KR, Cardnell RJ, Nilsson MB, Heeke S, Park EM, Kundu ST, Diao L, Wang Q, Shen L, Xi Y, Maria Della Corte C, Fan Y, ... ... Minna JD, et al. SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models. Biorxiv : the Preprint Server For Biology. PMID 32577652 DOI: 10.1101/2020.05.28.122291 |
0.3 |
|
| 2020 |
Hight SK, Mootz A, Kollipara RK, McMillan E, Yenerall P, Otaki Y, Li LS, Avila K, Peyton M, Rodriguez-Canales J, Mino B, Villalobos P, Girard L, Dospoy P, Larsen J, ... ... Minna JD, et al. An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis. Neoplasia (New York, N.Y.). 22: 294-310. PMID 32512502 DOI: 10.1016/j.neo.2020.04.005 |
0.389 |
|
| 2020 |
Luo SY, Kwok HH, Yang PC, Ip MS, Minna JD, Lam DC. Expression of large tumour suppressor (LATS) kinases modulates chemotherapy response in advanced non-small cell lung cancer. Translational Lung Cancer Research. 9: 294-305. PMID 32420069 DOI: 10.21037/tlcr.2020.03.26 |
0.358 |
|
| 2020 |
Poirier JT, George J, Owonikoko TK, Berns A, Brambilla E, Byers LA, Carbone D, Chen HJ, Christensen CL, Dive C, Farago AF, Govindan R, Hann C, Hellmann MD, Horn L, ... ... Minna J, et al. New approaches to small cell lung cancer therapy : from the laboratory to the clinic. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 32018053 DOI: 10.1016/J.Jtho.2020.01.016 |
0.416 |
|
| 2020 |
Mender I, Batten K, Peyton M, Vemula A, Cornelius C, Girard L, Gao B, Minna JD, Shay JW. SLC43A3 is a Biomarker of Sensitivity to the Telomeric DNA Damage Mediator 6-Thio-2'-Deoxyguanosine. Cancer Research. PMID 31948943 DOI: 10.1158/0008-5472.Can-19-2257 |
0.305 |
|
| 2020 |
Wang S, Rong R, Yang DM, Fujimoto J, Yan S, Cai L, Yang L, Luo D, Behrens C, Parra ER, Yao B, Xu L, Wang T, Zhan X, Wistuba II, ... Minna J, et al. Computational staining of pathology images to study the tumor microenvironment in lung cancer. Cancer Research. PMID 31915129 DOI: 10.1158/0008-5472.Can-19-1629 |
0.343 |
|
| 2020 |
Li R, Salehi-Rad R, Momcilovic M, Ong S, Lim R, Huang ZL, Tran L, Jing Z, Paul M, Teitell M, Minna J, Shackelford D, Kostyantyn K, Liu B, Dubinett S. Abstract 1016: Inhibition of chemokine-induced myeloid cells potentiates the anti-PD-1 response in KRAS/LKB1 mutant non-small cell lung cancer Immunology. DOI: 10.1158/1538-7445.Am2020-1016 |
0.342 |
|
| 2020 |
Flaming J, Chandra R, Girard L, Ganguly D, Toombs J, Minna J, Brekken R. 746 Non small-cell lung cancer cells and cancer-associated fibroblasts drive macrophage polarization in a novel co-culture model Journal For Immunotherapy of Cancer. 8: A793-A794. DOI: 10.1136/jitc-2020-sitc2020.0746 |
0.304 |
|
| 2020 |
Flaming J, Girard L, Brekken R, Minna J. B31 Development of Multicell-Type Organoid Cultures for Preclinical Studies of Immunotherapeutics for Lung Cancer Journal of Thoracic Oncology. 15: S36. DOI: 10.1016/j.jtho.2019.12.096 |
0.325 |
|
| 2020 |
Yenerall P, Das A, Wang S, Kollipara R, Li H, Shan Li L, Villalobos P, Flaming J, Huffman K, Timmons B, Gilbreath C, Sonavane R, Rodriguez-Canales J, Moran C, Behrens C, ... ... Minna J, et al. A17 Inhibition of RUVBL1/2 ATPase Activity Drives Immune Infiltration and Radiosensitizes Non-Small Cell Lung Cancer Journal of Thoracic Oncology. 15: S17-S18. DOI: 10.1016/J.Jtho.2019.12.046 |
0.339 |
|
| 2019 |
Yenerall P, Das AK, Wang S, Kollipara RK, Li LS, Villalobos P, Flaming J, Lin YF, Huffman K, Timmons BC, Gilbreath C, Sonavane R, Kinch LN, Rodriguez-Canales J, Moran C, ... ... Minna JD, et al. RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer. Cell Chemical Biology. PMID 31883965 DOI: 10.1016/J.Chembiol.2019.12.005 |
0.394 |
|
| 2019 |
Zi Z, Zhang Y, Zhang P, Ding Q, Chu M, Chen Y, Minna JD, Yu Y. A Proteomic Connectivity Map for Characterizing the Tumor Adaptive Response to Small Molecule Chemical Perturbagens. Acs Chemical Biology. PMID 31846293 DOI: 10.1021/Acschembio.9B00694 |
0.344 |
|
| 2019 |
Shimada Y, Kudo Y, Maehara S, Matsubayashi J, Otaki Y, Kajiwara N, Ohira T, Minna JD, Ikeda N. UCHL1 has prognostic relevance and is a therapeutic target for high-grade neuroendocrine lung cancers. Cancer Science. PMID 31845438 DOI: 10.1111/cas.14284 |
0.432 |
|
| 2019 |
Mulshine JL, Ujhazy P, Antman M, Burgess CM, Kuzmin I, Bunn PA, Johnson BE, Roth JA, Pass HI, Ross SM, Aldige CR, Wistuba II, Minna JD. From clinical specimens to human cancer preclinical models-a journey the NCI-cell line database-25 years later. Journal of Cellular Biochemistry. PMID 31803961 DOI: 10.1002/jcb.29564 |
0.337 |
|
| 2019 |
Wang S, Wang T, Yang L, Yang DM, Fujimoto J, Yi F, Luo X, Yang Y, Yao B, Lin S, Moran C, Kalhor N, Weissferdt A, Minna J, Xie Y, et al. ConvPath: A software tool for lung adenocarcinoma digital pathological image analysis aided by a convolutional neural network. Ebiomedicine. PMID 31767541 DOI: 10.1016/J.Ebiom.2019.10.033 |
0.317 |
|
| 2019 |
Raymond AC, Gao B, Girard L, Minna JD, Gomika Udugamasooriya D. Unbiased peptoid combinatorial cell screen identifies plectin protein as a potential biomarker for lung cancer stem cells. Scientific Reports. 9: 14954. PMID 31628412 DOI: 10.1038/s41598-019-51004-3 |
0.442 |
|
| 2019 |
Chen PH, Cai L, Huffman K, Yang C, Kim J, Faubert B, Boroughs L, Ko B, Sudderth J, McMillan EA, Girard L, Chen D, Peyton M, Shields MD, Yao B, ... ... Minna JD, et al. Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells. Molecular Cell. PMID 31564558 DOI: 10.1016/J.Molcel.2019.08.028 |
0.343 |
|
| 2019 |
Cai L, Lin S, Girard L, Zhou Y, Yang L, Ci B, Zhou Q, Luo D, Yao B, Tang H, Allen J, Huffman K, Gazdar A, Heymach J, Wistuba I, ... ... Minna J, et al. Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer. Oncogene. PMID 31501522 DOI: 10.1038/S41388-019-1000-6 |
0.342 |
|
| 2019 |
Wang XD, Hu R, Ding Q, Savage TK, Huffman KE, Williams N, Cobb MH, Minna JD, Johnson JE, Yu Y. Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells. Nature Communications. 10: 3201. PMID 31324758 DOI: 10.1038/S41467-019-11153-5 |
0.39 |
|
| 2019 |
Faubert B, DeBerardinis RJ, Minna JD. AIF: an acquired metabolic liability in lung cancer. Cell Research. PMID 31267018 DOI: 10.1038/s41422-019-0197-9 |
0.351 |
|
| 2019 |
Cai L, Luo D, Yao B, Yang DM, Lin S, Girard L, DeBerardinis RJ, Minna JD, Xie Y, Xiao G. Systematic Analysis of Gene Expression in Lung Adenocarcinoma and Squamous Cell Carcinoma with a Case Study of and . Cancers. 11. PMID 31242643 DOI: 10.3390/Cancers11060886 |
0.422 |
|
| 2019 |
Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, et al. Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nature Reviews. Cancer. PMID 31175338 DOI: 10.1038/S41568-019-0164-2 |
0.356 |
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| 2019 |
Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, ... ... Minna JD, et al. Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells. Nature. PMID 31043737 DOI: 10.1038/S41586-019-1133-3 |
0.32 |
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| 2019 |
Galan-Cobo A, Sitthideatphaiboon P, Qu X, Poteete A, Pisegna MA, Tong P, Chen PH, Boroughs LK, Rodriguez MLM, Zhang W, Parlati F, Wang J, Gandhi V, Skoulidis F, DeBerardinis RJ, ... Minna JD, et al. LKB1 and KEAP1/NRF2 pathways cooperatively promote metabolic reprogramming with enhanced glutamine dependence in KRAS-mutant lung adenocarcinoma. Cancer Research. PMID 31040157 DOI: 10.1158/0008-5472.Can-18-3527 |
0.31 |
|
| 2019 |
Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, et al. Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nature Reviews. Cancer. PMID 30926931 DOI: 10.1038/S41568-019-0133-9 |
0.39 |
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| 2019 |
Gazdar AF, Minna JD. Small cell lung cancers made from scratch. The Journal of Experimental Medicine. 216: 476-478. PMID 30760489 DOI: 10.1084/jem.20182216 |
0.345 |
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| 2019 |
Li R, Salehi-Rad R, Ong S, Momcilovic M, Liu B, Lim R, Tran L, Huang Z, Jing Z, Paul M, Krysan K, Park S, Minna J, Teitell M, Shackelford D, et al. Abstract 2710: Depletion of CXCR2-dependent myeloid-derived suppressor cells (MDSCs) overcomes anti-PD-1 resistance in a murine model of LKB1-deficient non-small cell lung cancer (NSCLC) with high mutational load Cancer Research. 79: 2710-2710. DOI: 10.1158/1538-7445.Am2019-2710 |
0.312 |
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| 2019 |
Goto D, Kizuki M, Uwatoko N, Kawai K, Koike M, Nakashima M, Miyazawa A, Tanaka I, Hase T, Morise M, Hasegawa Y, Minna J, Sato M. P2.03-23 UHRF1 as a Potential Therapeutic Target for KRAS Mutated Non-Small Cell Lung Cancer Journal of Thoracic Oncology. 14: S692. DOI: 10.1016/j.jtho.2019.08.1470 |
0.392 |
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| 2018 |
Cai L, Lin S, Girard L, Zhou Y, Yang L, Ci B, Zhou Q, Luo D, Yao B, Tang H, Allen J, Huffman K, Gazdar A, Heymach J, Wistuba I, ... ... Minna J, et al. LCE: an open web portal to explore gene expression and clinical associations in lung cancer. Oncogene. PMID 30532070 DOI: 10.1038/S41388-018-0588-2 |
0.371 |
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| 2018 |
Updegraff BL, Zhou X, Guo Y, Padanad MS, Chen PH, Yang C, Sudderth J, Rodriguez-Tirado C, Girard L, Minna JD, Mishra P, DeBerardinis RJ, O'Donnell KA. Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism. Cell Reports. 25: 2223-2233.e6. PMID 30463017 DOI: 10.1016/j.celrep.2018.10.100 |
0.419 |
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| 2018 |
Yan X, Zhang X, Wang L, Zhang R, Pu X, Wu S, Li L, Tong P, Wang J, Meng Q, Jensen VB, Girard L, Minna JD, Roth JA, Swisher SG, et al. Inhibition of thioredoxin/thioredoxin reductase induces synthetic lethality in lung cancers with compromised glutathione homeostasis. Cancer Research. PMID 30401714 DOI: 10.1158/0008-5472.CAN-18-1938 |
0.457 |
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| 2018 |
Ruder D, Papadimitrakopoulou V, Shien K, Behrens C, Kalhor N, Chen H, Shen L, Lee JJ, Hong WK, Tang X, Girard L, Minna JD, Diao L, Wang J, Mino B, et al. Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of -altered non-small cell lung cancer. Oncotarget. 9: 33995-34008. PMID 30338041 DOI: 10.18632/oncotarget.26129 |
0.46 |
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| 2018 |
Xie Y, Lu W, Wang S, Tang X, Tang H, Zhou Y, Moran C, Behrens C, Roth JA, Zhou Q, Johnson DH, Swisher SG, Heymach JV, Papadimitrakopoulou VA, Xiao G, ... Minna JD, et al. Validation of the 12-gene predictive signature for Adjuvant Chemotherapy Response in Lung Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30287547 DOI: 10.1158/1078-0432.Ccr-17-2543 |
0.379 |
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| 2018 |
Pozo K, Kelenis DP, Minna JD, Johnson JE. Different Originating Cells Underlie Intertumoral Heterogeneity in Lung Neuroendocrine Tumors. Cancer Discovery. 8: 1216-1218. PMID 30279195 DOI: 10.1158/2159-8290.Cd-18-0979 |
0.402 |
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| 2018 |
Hiramitsu S, Ishikawa T, Lee WR, Khan T, Crumbley C, Khwaja N, Zamanian F, Asghari A, Sen M, Zhang Y, Hawse JR, Minna JD, Umetani M. Estrogen Receptor Beta-Mediated Modulation of Lung Cancer Cell Proliferation by 27-Hydroxycholesterol. Frontiers in Endocrinology. 9: 470. PMID 30190703 DOI: 10.3389/Fendo.2018.00470 |
0.423 |
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| 2018 |
Nichols BA, Oswald NW, McMillan EA, McGlynn K, Yan J, Kim MS, Saha J, Mallipeddi PL, LaDuke SA, Villalobos PA, Rodriguez-Canales J, Wistuba II, Posner BA, Davis AJ, Minna JD, et al. HORMAD1 is a negative prognostic indicator in lung adenocarcinoma and specifies resistance to oxidative and genotoxic stress. Cancer Research. PMID 30185546 DOI: 10.1158/0008-5472.Can-18-1377 |
0.366 |
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| 2018 |
Pozo K, Minna JD, Johnson JE. Corrigendum: Identifying a missing lineage driver in a subset of lung neuroendocrine tumors. Genes & Development. 32: 1266. PMID 30181362 DOI: 10.1101/Gad.319129.118 |
0.314 |
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| 2018 |
Huang F, Ni M, Chalishazar MD, Huffman KE, Kim J, Cai L, Shi X, Cai F, Zacharias LG, Ireland AS, Li K, Gu W, Kaushik AK, Liu X, Gazdar AF, ... ... Minna JD, et al. Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers. Cell Metabolism. PMID 30043754 DOI: 10.1016/J.Cmet.2018.06.005 |
0.368 |
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| 2018 |
Du L, Zhao Z, Suraokar M, Shelton SS, Ma X, Hsiao TH, Minna JD, Wistuba I, Pertsemlidis A. LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer. Oncotarget. 9: 29601-29618. PMID 30038707 DOI: 10.18632/Oncotarget.25642 |
0.466 |
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| 2018 |
Mender I, LaRanger R, Luitel K, Peyton M, Girard L, Lai TP, Batten K, Cornelius C, Dalvi MP, Ramirez M, Du W, Wu LF, Altschuler SJ, Brekken R, Martinez ED, ... Minna JD, et al. Telomerase-Mediated Strategy for Overcoming Non-Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance. Neoplasia (New York, N.Y.). 20: 826-837. PMID 30015158 DOI: 10.1016/J.Neo.2018.06.002 |
0.408 |
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| 2018 |
Pozo K, Minna JD, Johnson JE. Identifying a missing lineage driver in a subset of lung neuroendocrine tumors. Genes & Development. 32: 865-867. PMID 29967289 DOI: 10.1101/Gad.316943.118 |
0.382 |
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| 2018 |
McMillan EA, Ryu MJ, Diep CH, Mendiratta S, Clemenceau JR, Vaden RM, Kim JH, Motoyaji T, Covington KR, Peyton M, Huffman K, Wu X, Girard L, Sung Y, Chen PH, ... ... Minna JD, et al. Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer. Cell. PMID 29681454 DOI: 10.1016/J.Cell.2018.03.028 |
0.302 |
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| 2018 |
Tanaka I, Sato M, Kato T, Goto D, Kakumu T, Miyazawa A, Yogo N, Hase T, Morise M, Sekido Y, Girard L, Minna JD, Byers LA, Heymach JV, Coombes KR, et al. eIF2β, a Subunit of Translation-Initiation Factor EIF2, Is a Potential Therapeutic Target for Non-Small Cell Lung Cancer. Cancer Science. PMID 29624814 DOI: 10.1111/cas.13602 |
0.458 |
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| 2018 |
Zhang W, Girard L, Zhang YA, Haruki T, Papari-Zareei M, Stastny V, Ghayee HK, Pacak K, Oliver TG, Minna JD, Gazdar AF. Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes. Translational Lung Cancer Research. 7: 32-49. PMID 29535911 DOI: 10.21037/Tlcr.2018.02.02 |
0.435 |
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| 2018 |
Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, ... Minna JD, et al. Silencing the Snail-dependent RNA splice regulator ESRP1 drives malignant transformation of human pulmonary epithelial cells. Cancer Research. PMID 29431637 DOI: 10.1158/0008-5472.Can-17-0315 |
0.346 |
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| 2018 |
He M, Liu S, Gallolu Kankanamalage S, Borromeo MD, Girard L, Gazdar AF, Minna JD, Johnson JE, Cobb MH. The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors. Translational Oncology. 11: 292-299. PMID 29413762 DOI: 10.1016/J.Tranon.2018.01.004 |
0.424 |
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| 2018 |
Shimada Y, Okano T, Yenerall P, Huffman K, Timmons B, Gao B, Deb D, Ikeda N, Minna JD. Exosomes secreted from mesenchymal NSCLC cells to promote invasiveness and metastatic capability of recipient cells through UCHL1. Journal of Clinical Oncology. 36: e24008-e24008. DOI: 10.1200/Jco.2018.36.15_Suppl.E24008 |
0.32 |
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| 2018 |
Minna JD, McMillan E, Girard L, Peyton M, Huffman K, Deb D, Yenerall P, Das A, Li L, Dalvi M, Gao B, Xie Y, Yu Y, Hight S, Vaden R, et al. Abstract IA12: Developing precision medicine-based new lung cancer therapeutics Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-Ia12 |
0.358 |
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| 2018 |
Yanagawa J, Fung E, Lee M, Wallace WD, Fishbein MC, Paul M, Krysan K, Minna JD, Guo R, Elashoff D, Lee JM, Dubinett SM. Abstract B20: Premalignant lung lesions demonstrate enhanced PD-L1 upregulation in response to interferon-gamma exposure Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B20 |
0.328 |
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| 2018 |
Pozo K, Kollipara RK, Minna JD, Gazdar AF, Johnson JE. Abstract B09: Evaluating transcription factor networks as targets for the treatment of small cell lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B09 |
0.318 |
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| 2018 |
Paul MK, Dutta S, Bisht B, Ramin S, Pagano P, Bitan G, Minna JD, Dubinett SM. Abstract 2015: Exosomes secreted by highly migratory premalignant lung epithelial cells promote epithelial mesenchymal transition and migration Cancer Research. 78: 2015-2015. DOI: 10.1158/1538-7445.Am2018-2015 |
0.337 |
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| 2018 |
Goto D, Tanaka I, Sato M, Kato T, Miyazawa A, Hase T, Morise M, Sekido Y, Girard L, Minna J, Byers L, Heymach J, Coombes K, Kondo M, Hasegawa Y. P1.03-13 eIF2β, A Subunit of Translation-Initiation Factor EIF2, as a Potential Therapeutic Target for Non-Small Cell Lung Cancer Journal of Thoracic Oncology. 13: S516-S517. DOI: 10.1016/J.JTHO.2018.08.694 |
0.38 |
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| 2018 |
Otaki Y, Yenerall P, Gao B, Peyton M, Avila K, Girard L, Li L, Das A, Huffman K, Timmons B, Park H, Deb D, Minna J. P3.03-14 Downregulation of FOXM1 Inhibits Tumor Proliferation, Colony Formation and Spheroid Formation of Non-Small Cell Lung Cancer Journal of Thoracic Oncology. 13: S915-S916. DOI: 10.1016/J.Jtho.2018.08.1691 |
0.403 |
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| 2017 |
Shimada Y, Minna JD. Exosome mediated phenotypic changes in lung cancer pathophysiology. Translational Cancer Research. 6: S1040-S1042. PMID 30613485 DOI: 10.21037/tcr.2017.07.09 |
0.385 |
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| 2017 |
Aisner DL, Sholl LM, Berry L, Rossi M, Chen H, Fujimoto J, Moreira AL, Ramalingam S, Villaruz LC, Otterson GA, Haura EB, Politi K, Glisson BS, Cetnar J, Garon E, ... ... Minna JD, et al. The Impact of Smoking and TP53 mutations in lung adenocarcinoma patients with targetable mutations - the Lung Cancer Mutation Consortium (LCMC2). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29217530 DOI: 10.1158/1078-0432.Ccr-17-2289 |
0.355 |
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| 2017 |
Gazdar AF, Bunn PA, Minna JD. Small-cell lung cancer: what we know, what we need to know and the path forward. Nature Reviews. Cancer. 17: 765. PMID 29123245 DOI: 10.1038/nrc.2017.106 |
0.388 |
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| 2017 |
Gazdar AF, Bunn PA, Minna JD. Small-cell lung cancer: what we know, what we need to know and the path forward. Nature Reviews. Cancer. 17: 725-737. PMID 29077690 DOI: 10.1038/nrc.2017.87 |
0.404 |
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| 2017 |
Pagano PC, Tran LM, Bendris N, O'Byrne S, Tse HT, Sharma S, Hoech JW, Park SJ, Liclican EL, Jing Z, Li R, Krysan K, Paul MK, Fontebasso Y, Larsen JE, ... ... Minna JD, et al. Identification of a human airway epithelial cell subpopulation with altered biophysical, molecular, and metastatic properties. Cancer Prevention Research (Philadelphia, Pa.). PMID 28754664 DOI: 10.1158/1940-6207.Capr-16-0335 |
0.362 |
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| 2017 |
Zhao X, Huffman KE, Fujimoto J, Canales JR, Girard L, Nie G, Heymach JV, Wistuba II, Minna JD, Yu Y. Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer. Journal of the American Society For Mass Spectrometry. PMID 28752479 DOI: 10.1007/S13361-017-1706-Z |
0.308 |
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| 2017 |
Goodwin J, Neugent ML, Lee SY, Choe JH, Choi H, Jenkins DMR, Ruthenborg RJ, Robinson MW, Jeong JY, Wake M, Abe H, Takeda N, Endo H, Inoue M, Xuan Z, ... ... Minna JD, et al. The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition. Nature Communications. 8: 15503. PMID 28548087 DOI: 10.1038/Ncomms15503 |
0.402 |
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| 2017 |
Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, ... ... Minna JD, et al. CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells. Nature. PMID 28538732 DOI: 10.1038/Nature22359 |
0.357 |
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| 2017 |
Dalvi MP, Wang L, Zhong R, Kollipara RK, Park H, Bayo J, Yenerall P, Zhou Y, Timmons BC, Rodriguez-Canales J, Behrens C, Mino B, Villalobos P, Parra ER, Suraokar M, ... ... Minna JD, et al. Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors. Cell Reports. 19: 1669-1684. PMID 28538184 DOI: 10.1016/J.Celrep.2017.04.077 |
0.33 |
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| 2017 |
Sen T, Tong P, Stewart CA, Cristea S, Valliani A, Shames DS, Redwood A, Fan Y, Li L, Glisson BS, Minna J, Sage J, Gibbons DL, Piwnica-Worms H, Heymach J, et al. CHK1 inhibition in small cell lung cancer produces single-agent activity in biomarker-defined disease subsets and combination activity with cisplatin or olaparib. Cancer Research. PMID 28490518 DOI: 10.1158/0008-5472.Can-16-3409 |
0.367 |
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| 2017 |
Zhang Y, Zhang L, Li R, Chang DW, Ye Y, Minna JD, Roth JA, Han B, Wu X. Genetic variations in cancer-related significantly mutated genes and lung cancer susceptibility. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 28383694 DOI: 10.1093/Annonc/Mdx161 |
0.353 |
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| 2017 |
Deb D, Rajaram S, Larsen JE, Dospoy PP, Marullo R, Li LS, Avila K, Cerchietti L, Xue F, Minna J, Altschuler SJ, Wu LF. Combination therapy targeting BCL6 and phospho-STAT3 defeats intra-tumor heterogeneity in a subset of non-small cell lung cancers. Cancer Research. PMID 28377453 DOI: 10.1158/0008-5472.Can-15-3052 |
0.392 |
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| 2017 |
Tang H, Wang S, Xiao G, Schiller J, Papadimitrakopoulou V, Minna J, Wistuba II, Xie Y. Comprehensive evaluation of published gene expression prognostic signatures for biomarker-based lung cancer clinical studies. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 28200038 DOI: 10.1093/Annonc/Mdw683 |
0.337 |
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| 2017 |
Kakumu T, Sato M, Goto D, Kato T, Yogo N, Hase T, Morise M, Fukui T, Yokoi K, Sekido Y, Girard L, Minna JD, Byers LA, Heymach JV, Coombes KR, et al. Identification of Proteasomal Catalytic Subunit PSMA6 as a Therapeutic Target for Lung Cancer. Cancer Science. PMID 28165654 DOI: 10.1111/cas.13185 |
0.457 |
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| 2017 |
Pelosof L, Ahn C, Gao A, Horn L, Madrigales A, Cox J, McGavic D, Minna JD, Gazdar AF, Schiller J. Proportion of Never-Smoker Non-Small Cell Lung Cancer Patients at Three Diverse Institutions. Journal of the National Cancer Institute. 109. PMID 28132018 DOI: 10.1093/jnci/djw295 |
0.366 |
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| 2017 |
Tagal V, Wei S, Zhang W, Brekken RA, Posner BA, Peyton M, Girard L, Hwang T, Wheeler DA, Minna JD, White MA, Gazdar AF, Roth MG. SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers. Nature Communications. 8: 14098. PMID 28102363 DOI: 10.1038/Ncomms14098 |
0.397 |
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| 2017 |
Shimada Y, Yenerall P, Avila K, Park H, Timmons B, Huffman K, Gao B, Deb D, Dalvi M, Minna JD. Abstract 907: Uptake of lung cancer exosomes induces migratory and invasive phenotypic changes in lung epithelial cells in an oncogene context dependent manner Cancer Research. 77: 907-907. DOI: 10.1158/1538-7445.Am2017-907 |
0.444 |
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| 2017 |
Deb D, Rajaram S, Larsen JE, Dospoy PP, Marullo R, Li L, Avila K, Cerchietti L, Minna JD, Wu LF, Altschuler SJ. Abstract 3950: A novel combination therapy targeting BCL6 and phospho-STAT3 defeats intratumor heterogeneity in a subset of non-small cell lung cancers Cancer Research. 77: 3950-3950. DOI: 10.1158/1538-7445.Am2017-3950 |
0.41 |
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| 2017 |
Zhang L, Zhang Y, Li R, Chang DW, Ye Y, Minna JD, Roth JA, Han B, Wu X. Abstract 1275: Genetic variations in cancer-related significantly mutated genes and lung cancer susceptibility Epidemiology. 77: 1275-1275. DOI: 10.1158/1538-7445.Am2017-1275 |
0.367 |
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| 2017 |
Shimada Y, Yenerall P, Huffman K, Avila K, Park H, Timmons B, Gao B, Deb D, Ikeda N, Minna J. MA 15.13 The Transfer of Exogenous UCHL-1 via Mesenchymal Lung Cancer Exosomes to Mediate Phenotypic Alterations of Recipients Journal of Thoracic Oncology. 12: S1865-S1866. DOI: 10.1016/J.Jtho.2017.09.594 |
0.368 |
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| 2017 |
Sato M, Kakumu T, Goto D, Kato T, Yogo N, Hase T, Morise M, Fukui T, Yokoi K, Sekido Y, Girard L, Minna J, Byers L, Heymach J, Coombes K, et al. P3.03-013 Identification of Proteosomal Catalytic Subunit PSMA6 as a Therapeutic Target for Lung Cancer through a Pooled shRNA Screen Journal of Thoracic Oncology. 12: S2277-S2278. DOI: 10.1016/j.jtho.2017.09.1639 |
0.322 |
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| 2017 |
Haruki T, Papari-Zareei M, Zhang W, Zhang Y, Stastny V, Minna J, Gazdar A. P1.15-005 Relationship Between MYC Family Status and Sensitivity to Aurora Kinase Inhibitors in Neuroendocrine and Other Lung Cancer Cell Lines Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2017.09.1041 |
0.351 |
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| 2017 |
Gao B, Peyton M, Huang C, Park H, Girard L, Sorrelle N, Dayoub A, Brekken R, Gazdar A, Minna J. 3D Spheroid/Organoid Models of Lung Cancer to Study Lung Cancer Pathogenesis and Testing of New Therapeutics Journal of Thoracic Oncology. 12: S1544. DOI: 10.1016/J.JTHO.2017.06.053 |
0.376 |
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| 2017 |
Zhou X, Updegraff B, Guo Y, Peyton M, Girard L, Larsen J, Xie X, Zhou Y, Hwang T, Xie Y, Rodriguez-Canales J, Villalobos P, Behrens C, Wistuba I, Minna J, et al. Dissecting the Role of PCDH7, an Oncogenic Cell Surface Receptor, in Non–Small Cell Lung Cancer Journal of Thoracic Oncology. 12: S1542. DOI: 10.1016/J.Jtho.2017.06.044 |
0.379 |
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| 2017 |
Zhao X, Huffman K, Fujimoto J, Canales J, Girard L, Guangjun N, Heymach J, Wistuba I, Minna J, Yu Y. Quantitative Proteomic Analysis of Core-Needle Biopsy of Lung Cancer Journal of Thoracic Oncology. 12: S1540-S1541. DOI: 10.1016/J.Jtho.2017.06.040 |
0.369 |
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| 2016 |
Gao B, Huang C, Kernstine K, Pelekanou V, Kluger Y, Jiang T, Peters-Hall JR, Coquelin M, Girard L, Zhang W, Huffman K, Oliver D, Kinose F, Haura E, Teer JK, ... ... Minna JD, et al. Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions. Oncotarget. PMID 28052041 DOI: 10.18632/Oncotarget.14366 |
0.352 |
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| 2016 |
Zhou X, Updegraff BL, Guo Y, Peyton M, Girard L, Larsen JE, Xie XJ, Zhou Y, Hwang TH, Xie Y, Rodriguez-Canales J, Villalobos P, Behrens C, Wistuba II, Minna J, et al. PROTOCADHERIN 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis. Cancer Research. PMID 27821484 DOI: 10.1158/0008-5472.Can-16-1267-T |
0.417 |
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| 2016 |
Kim J, McMillan E, Kim HS, Venkateswaran N, Makkar G, Rodriguez-Canales J, Villalobos P, Neggers JE, Mendiratta S, Wei S, Landesman Y, Senapedis W, Baloglu E, Chow CB, Frink RE, ... ... Minna JD, et al. XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer. Nature. PMID 27680702 DOI: 10.1038/nature19771 |
0.433 |
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| 2016 |
Yan Y, Liu L, Xiong H, Miller JB, Zhou K, Kos P, Huffman KE, Elkassih S, Norman JW, Carstens R, Kim J, Minna JD, Siegwart DJ. Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27621434 DOI: 10.1073/Pnas.1606886113 |
0.331 |
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| 2016 |
Frankel AE, Liu X, Minna JD. Developing EZH2-Targeted Therapy for Lung Cancer. Cancer Discovery. 6: 949-52. PMID 27587466 DOI: 10.1158/2159-8290.Cd-16-0800 |
0.378 |
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| 2016 |
Larsen JE, Nathan V, Osborne JK, Farrow RK, Deb D, Sullivan JP, Dospoy PD, Augustyn A, Hight SK, Sato M, Girard L, Behrens C, Wistuba II, Gazdar AF, Hayward NK, ... Minna JD, et al. ZEB1 drives epithelial-to-mesenchymal transition in lung cancer. The Journal of Clinical Investigation. PMID 27500490 DOI: 10.1172/JCI76725 |
0.374 |
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| 2016 |
Padanad MS, Konstantinidou G, Venkateswaran N, Melegari M, Rindhe S, Mitsche M, Yang C, Batten K, Huffman KE, Liu J, Tang X, Rodriguez-Canales J, Kalhor N, Shay JW, Minna JD, et al. Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis. Cell Reports. PMID 27477280 DOI: 10.1016/J.Celrep.2016.07.009 |
0.313 |
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| 2016 |
Borromeo MD, Savage TK, Kollipara RK, He M, Augustyn A, Osborne JK, Girard L, Minna JD, Gazdar AF, Cobb MH, Johnson JE. ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs. Cell Reports. PMID 27452466 DOI: 10.1016/J.Celrep.2016.06.081 |
0.309 |
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| 2016 |
Minna JD, Johnson JE. Opening a Chromatin Gate to Metastasis. Cell. 166: 275-276. PMID 27419866 DOI: 10.1016/J.Cell.2016.06.031 |
0.315 |
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| 2016 |
Girard L, Rodriguez-Canales J, Behrens C, Thompson DM, Botros IW, Tang H, Xie Y, Rekhtman N, Travis WD, Wistuba II, Minna JD, Gazdar AF. An Expression Signature as an Aid to the Histologic Classification of Non-Small Cell Lung Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27354471 DOI: 10.1158/1078-0432.CCR-15-2900 |
0.393 |
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| 2016 |
Kumar RT, Liu S, Minna JD, Prasad S. Monitoring drug induced apoptosis and treatment sensitivity in non-small cell lung carcinoma using Dielectrophoresis. Biochimica Et Biophysica Acta. PMID 27262539 DOI: 10.1016/j.bbagen.2016.05.039 |
0.301 |
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| 2016 |
Gazdar AF, Minna JD. Developing New, Rational Therapies for Recalcitrant Small Cell Lung Cancer. Journal of the National Cancer Institute. 108. PMID 27247352 DOI: 10.1093/jnci/djw119 |
0.386 |
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| 2016 |
Frink RE, Peyton M, Schiller JH, Gazdar AF, Shay JW, Minna JD. Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner. Oncotarget. PMID 27192120 DOI: 10.18632/Oncotarget.9335 |
0.322 |
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| 2016 |
Desai TJ, Toombs JE, Minna JD, Brekken RA, Udugamasooriya DG. Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1. Oncotarget. PMID 27120792 DOI: 10.18632/oncotarget.8929 |
0.357 |
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| 2016 |
Regan E, Sibley RC, Cenik BK, Silva A, Girard L, Minna JD, Dellinger MT. Identification of Gene Expression Differences between Lymphangiogenic and Non-Lymphangiogenic Non-Small Cell Lung Cancer Cell Lines. Plos One. 11: e0150963. PMID 26950548 DOI: 10.1371/journal.pone.0150963 |
0.373 |
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| 2016 |
Bunn PA, Minna J, Augustyn A, Gazdar A, Ouadah Y, Krasnow MA, Berns A, Brambilla E, Rekhtman N, Massion PP, Niederst M, Peifer M, Yokota J, Govindan R, Poirier J, et al. Small Cell Lung Cancer: Can recent advances in biology and molecular biology be translated into improved outcomes? Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26829312 DOI: 10.1016/J.Jtho.2016.01.012 |
0.362 |
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| 2016 |
Young JH, Peyton M, Kim HS, McMillan E, Minna JD, White MA, Marcotte EM. Computational Discovery of Pathway-Level Genetic Vulnerabilities in Non-Small-Cell Lung Cancer. Bioinformatics (Oxford, England). PMID 26755624 DOI: 10.1093/Bioinformatics/Btw010 |
0.43 |
|
| 2016 |
Hu R, Huffman KE, Chu M, Zhang Y, Minna JD, Yu Y. Quantitative Secretomic Analysis Identifies Extracellular Protein Factors that Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer. Journal of Proteome Research. PMID 26736068 DOI: 10.1021/Acs.Jproteome.5B00819 |
0.408 |
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| 2016 |
Padanad MS, Konstantinidou G, Yang C, Melegari M, Venkateswaran N, Batten K, Huffman KE, Shay JW, Minna JD, DeBerardinis RJ, Scaglioni PP. Abstract B22: Acyl-CoA synthetase long-chain family member 3 dependent lipid homeostasis is required for mutant KRAS driven lung cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-B22 |
0.44 |
|
| 2016 |
DeNicola GM, Chen P, Mullarky E, Chio C, Asara JM, Minna JD, Tuveson DA, DeBerardinis RJ, Cantley LC. Abstract B04: NRF2 regulates serine biosynthesis in pancreatic ductal adenocarcinoma Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B04 |
0.312 |
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| 2016 |
Parra ER, Tong P, Kadara H, Papadimitrakopoulou V, Izzo J, Rodriguez-Canales J, Behrens C, Minna JD, Wang J, Wistuba II, Heymach JV, Skoulidis F. Abstract 532: Impact of APOBEC mutagenesis on the immune microenvironment of lung adenocarcinoma (LUAC) Cancer Research. 76: 532-532. DOI: 10.1158/1538-7445.Am2016-532 |
0.308 |
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| 2015 |
Zhang YA, Ma X, Sathe A, Fujimoto J, Wistuba II, Lam S, Yatabe Y, Wang YW, Stastny V, Gao B, Larsen JE, Girard L, Liu X, Song K, Behrens C, ... ... Minna JD, et al. Validation of SCT Methylation As a Hallmark Biomarker for Lung Cancers. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26725182 DOI: 10.1016/J.Jtho.2015.11.004 |
0.387 |
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| 2015 |
Gazdar AF, Hirsch FR, Minna JD. From Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung Cancers. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26723239 DOI: 10.1016/j.jtho.2015.10.009 |
0.361 |
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| 2015 |
Riquelme E, Behrens C, Lin HY, Simon GR, Papadimitrakopoulou VA, Izzo J, Moran C, Kalhor N, Lee JJ, Minna JD, Wistuba II. Modulation of EZH2 expression by MEK-ERK or PI3K-AKT signaling in lung cancer is dictated by different KRAS oncogene mutations. Cancer Research. PMID 26676756 DOI: 10.1158/0008-5472.CAN-15-1141 |
0.376 |
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| 2015 |
Li H, Hu J, Wu S, Wang L, Cao X, Zhang X, Dai B, Cao M, Shao R, Zhang R, Majidi M, Ji L, Heymach JV, Wang M, Pan S, ... Minna J, et al. Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells. Oncotarget. PMID 26657290 DOI: 10.18632/oncotarget.6516 |
0.438 |
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| 2015 |
Ferrarotto R, Goonatilake R, Yoo SY, Tong P, Giri U, Peng S, Minna JD, Girard L, Wang Y, Wang L, Li L, Diao L, Peng DH, Gibbons DL, Glisson BS, et al. Epithelial-Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor-Mediated Apoptosis in Non-Small Cell Lung Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26597303 DOI: 10.1158/1078-0432.Ccr-14-2890 |
0.41 |
|
| 2015 |
Lou TF, Sethuraman D, Dospoy P, Srivastva P, Kim HS, Kim J, Ma X, Chen PH, Huffman KE, Frink RE, Larsen JE, Lewis CM, Um SW, Kim DH, Ahn JM, ... ... Minna JD, et al. Cancer-specific production of N-acetylaspartate via NAT8L overexpression in non-small cell lung cancer and its potential as a circulating biomarker. Cancer Prevention Research (Philadelphia, Pa.). PMID 26511490 DOI: 10.1158/1940-6207.Capr-14-0287 |
0.454 |
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| 2015 |
Matharage JM, Minna JD, Brekken RA, Udugamasooriya DG. Unbiased Selection of Peptide-Peptoid Hybrids Specific for Lung Cancer Compared to Normal Lung Epithelial Cells. Acs Chemical Biology. 10: 2891-9. PMID 26509598 DOI: 10.1021/acschembio.5b00592 |
0.36 |
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| 2015 |
DeNicola GM, Chen PH, Mullarky E, Sudderth JA, Hu Z, Wu D, Tang H, Xie Y, Asara JM, Huffman KE, Wistuba II, Minna JD, DeBerardinis RJ, Cantley LC. NRF2 regulates serine biosynthesis in non-small cell lung cancer. Nature Genetics. PMID 26482881 DOI: 10.1038/Ng.3421 |
0.388 |
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| 2015 |
Wei Q, Chen ZH, Wang L, Zhang T, Duan L, Behrens C, Wistuba II, Minna JD, Gao B, Luo JH, Liu ZP. LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells. Oncogene. PMID 26364604 DOI: 10.1038/onc.2015.328 |
0.471 |
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| 2015 |
Elkin SR, Bendris N, Reis C, Zhou Y, Xie Y, Huffman KE, Minna JD, Schmid SL. A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells. Cancer Research. PMID 26359453 DOI: 10.1158/0008-5472.Can-15-0939 |
0.378 |
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| 2015 |
Kim J, Sato M, Choi JW, Kim HW, Yeh BI, Larsen JE, Minna JD, Cha JH, Jeong Y. Nuclear Receptor Expression and Function in Human Lung Cancer Pathogenesis. Plos One. 10: e0134842. PMID 26244663 DOI: 10.1371/journal.pone.0134842 |
0.398 |
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| 2015 |
Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Rodriguez Canales J, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, ... ... Minna JD, et al. Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities. Cancer Discovery. PMID 26069186 DOI: 10.1158/2159-8290.Cd-14-1236 |
0.361 |
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| 2015 |
Pietanza MC, Byers LA, Minna JD, Rudin CM. Small cell lung cancer: will recent progress lead to improved outcomes? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2244-55. PMID 25979931 DOI: 10.1158/1078-0432.CCR-14-2958 |
0.32 |
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| 2015 |
Cardnell RJ, Behrens C, Diao L, Fan Y, Tang X, Tong P, Minna JD, Mills GB, Heymach JV, Wistuba II, Wang J, Byers LA. An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25878335 DOI: 10.1158/1078-0432.Ccr-14-3286 |
0.348 |
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| 2015 |
Sholl LM, Aisner DL, Varella-Garcia M, Berry LD, Dias-Santagata D, Wistuba II, Chen H, Fujimoto J, Kugler K, Franklin WA, Iafrate AJ, Ladanyi M, Kris MG, Johnson BE, Bunn PA, ... Minna JD, et al. Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 768-77. PMID 25738220 DOI: 10.1097/JTO.0000000000000516 |
0.35 |
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| 2015 |
Tian H, Lu JY, Shao C, Huffman KE, Carstens RM, Larsen JE, Girard L, Liu H, Rodriguez-Canales J, Frenkel EP, Wistuba II, Minna JD, Hofmann SL. Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5. Molecular Cancer Research : McR. 13: 784-94. PMID 25573953 DOI: 10.1158/1541-7786.Mcr-14-0608 |
0.343 |
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| 2015 |
Villaruz LC, Socinski MA, Abberbock S, Berry LD, Johnson BE, Kwiatkowski DJ, Iafrate AJ, Varella-Garcia M, Franklin WA, Camidge DR, Sequist LV, Haura EB, Ladanyi M, Kurland BF, Kugler K, ... Minna JD, et al. Clinicopathologic features and outcomes of patients with lung adenocarcinomas harboring BRAF mutations in the Lung Cancer Mutation Consortium. Cancer. 121: 448-56. PMID 25273224 DOI: 10.1002/Cncr.29042 |
0.354 |
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| 2015 |
Pelosof LC, Ahn C, Madrigales A, Cox J, Minna JD, Schiller JH. Rate of never smokers in non small cell lung cancer (NSCLC) patients. Journal of Clinical Oncology. 33: e19007-e19007. DOI: 10.1200/JCO.2015.33.15_SUPPL.E19007 |
0.404 |
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| 2015 |
Park SJ, Walser TC, Tran LM, Perdomo C, Wang T, Hong L, Pagano PC, Liclican EL, Larsen JE, Krysan K, Fishbein MC, Minna JD, Lenburg ME, Avrum S, Dubinett S. Abstract B22: The role of e-cigarette exposure on pulmonary epithelial cell transformation Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-B22 |
0.317 |
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| 2015 |
Skoulidis F, Byers L, Diao L, Papadimitrakopoulou V, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Rodriguez-Canales J, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, ... ... Minna JD, et al. Abstract 968: Co-occurring genomic alterations define major subsets ofKRAS-mutant lung adenocarcinoma (LUAC) with distinct biology and therapeutic vulnerabilities Cancer Research. 75: 968-968. DOI: 10.1158/1538-7445.Am2015-968 |
0.316 |
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| 2015 |
Yenerall PM, Kollipara R, Carstens R, Huffman K, Girard L, Rodriguez J, Wistuba I, Mangelsdorf D, Minna J, Kittler R. Abstract 4779: RUVBL1 and RUBVL2 are chromatin remodelers that represent prognostic and novel therapeutic targets for a subset of non-small cell lung cancers (NSCLCs) Cancer Research. 75: 4779-4779. DOI: 10.1158/1538-7445.Am2015-4779 |
0.42 |
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| 2015 |
Boroughs LK, Chen P, Cai L, Rodriguez M, Zhang W, Huffman KE, Byers LA, Girard L, Gazdar AF, Heymach JV, White MA, Minna JD, Emberley E, Pan A, Parlati F, et al. Abstract 4710: Evaluation of the glutaminase inhibitor CB-839 in non-small cell lung cancer Cancer Research. 75: 4710-4710. DOI: 10.1158/1538-7445.Am2015-4710 |
0.406 |
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| 2015 |
Tian H, Qi X, Huffman K, Minna J, Hofmann SL. Abstract 3562: Protein palmitoylation in breast cancer: DHHC5 palmitoyltransferase as a potential therapeutic target Cancer Research. 75: 3562-3562. DOI: 10.1158/1538-7445.Am2015-3562 |
0.323 |
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| 2015 |
Zhang W, Yao Y, Zhou Y, Ma X, Yan J, Wang T, Girard L, Minna J, Xiao G, Xie Y, Gazdar A. Abstract 2965: Identification of SMARCA4/BRG1 mutation types in NSCLC cell lines and tumors Cancer Research. 75: 2965-2965. DOI: 10.1158/1538-7445.Am2015-2965 |
0.382 |
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| 2015 |
Mukherjee S, Glisson BS, Minna JD, Cardnell RJ, Girard L, Gazdar A, Diao L, Wang J, Byers LA. Abstract 2961: Characterization of methylation profiles reveals distinct epigenomic patterns in SCLC and NSCLC Cancer Research. 75: 2961-2961. DOI: 10.1158/1538-7445.Am2015-2961 |
0.389 |
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| 2014 |
Lin SH, Wang J, Saintigny P, Wu CC, Giri U, Zhang J, Menju T, Diao L, Byers L, Weinstein JN, Coombes KR, Girard L, Komaki R, Wistuba II, Date H, ... Minna JD, et al. Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition. Bmc Genomics. 15: 1079. PMID 25486910 DOI: 10.1186/1471-2164-15-1079 |
0.536 |
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| 2014 |
Augustyn A, Borromeo M, Wang T, Fujimoto J, Shao C, Dospoy PD, Lee V, Tan C, Sullivan JP, Larsen JE, Girard L, Behrens C, Wistuba II, Xie Y, Cobb MH, ... ... Minna JD, et al. ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers. Proceedings of the National Academy of Sciences of the United States of America. 111: 14788-93. PMID 25267614 DOI: 10.1073/Pnas.1410419111 |
0.46 |
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| 2014 |
Gao W, Wang M, Wang L, Lu H, Wu S, Dai B, Ou Z, Zhang L, Heymach JV, Gold KA, Minna J, Roth JA, Hofstetter WL, Swisher SG, Fang B. Selective antitumor activity of ibrutinib in EGFR-mutant non-small cell lung cancer cells. Journal of the National Cancer Institute. 106. PMID 25214559 DOI: 10.1093/jnci/dju204 |
0.336 |
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| 2014 |
Pu X, Wang L, Chang JY, Hildebrandt MA, Ye Y, Lu C, Skinner HD, Niu N, Jenkins GD, Komaki R, Minna JD, Roth JA, Weinshilboum RM, Wu X. Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer. Clinical Pharmacology and Therapeutics. 96: 609-15. PMID 25054431 DOI: 10.1038/Clpt.2014.154 |
0.322 |
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| 2014 |
Luo SY, Sit KY, Sihoe AD, Suen WS, Au WK, Tang X, Ma ES, Chan WK, Wistuba II, Minna JD, Tsao GS, Lam DC. Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas. Lung Cancer (Amsterdam, Netherlands). 85: 282-92. PMID 24976335 DOI: 10.1016/j.lungcan.2014.05.025 |
0.414 |
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| 2014 |
Taguchi A, Taylor AD, Rodriguez J, CeliktaÅŸ M, Liu H, Ma X, Zhang Q, Wong CH, Chin A, Girard L, Behrens C, Lam WL, Lam S, Minna JD, Wistuba II, et al. A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets. Cancer Research. 74: 4694-705. PMID 24970476 DOI: 10.1158/0008-5472.CAN-13-3725 |
0.337 |
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| 2014 |
Shao C, Sullivan JP, Girard L, Augustyn A, Yenerall P, Rodriguez-Canales J, Liu H, Behrens C, Shay JW, Wistuba II, Minna JD. Essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells is associated with the STAT3 pathway. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4154-66. PMID 24907115 DOI: 10.1158/1078-0432.Ccr-13-3292 |
0.384 |
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| 2014 |
Riquelme E, Suraokar M, Behrens C, Lin HY, Girard L, Nilsson MB, Simon G, Wang J, Coombes KR, Lee JJ, Hong WK, Heymach J, Minna JD, Wistuba II. VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3849-61. PMID 24850841 DOI: 10.1158/1078-0432.Ccr-13-1916 |
0.396 |
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| 2014 |
Kris MG, Johnson BE, Berry LD, Kwiatkowski DJ, Iafrate AJ, Wistuba II, Varella-Garcia M, Franklin WA, Aronson SL, Su PF, Shyr Y, Camidge DR, Sequist LV, Glisson BS, Khuri FR, ... ... Minna JD, et al. Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. Jama. 311: 1998-2006. PMID 24846037 DOI: 10.1001/Jama.2014.3741 |
0.331 |
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| 2014 |
Kaisani A, Delgado O, Fasciani G, Kim SB, Wright WE, Minna JD, Shay JW. Branching morphogenesis of immortalized human bronchial epithelial cells in three-dimensional culture. Differentiation; Research in Biological Diversity. 87: 119-26. PMID 24830354 DOI: 10.1016/J.Diff.2014.02.003 |
0.317 |
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| 2014 |
Li X, Xu Z, Du W, Zhang Z, Wei Y, Wang H, Zhu Z, Qin L, Wang L, Niu Q, Zhao X, Girard L, Gong Y, Ma Z, Sun B, ... ... Minna JD, et al. Aiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells. Cancer Cell. 25: 575-89. PMID 24823637 DOI: 10.1016/j.ccr.2014.03.020 |
0.408 |
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| 2014 |
Delgado O, Batten KG, Richardson JA, Xie XJ, Gazdar AF, Kaisani AA, Girard L, Behrens C, Suraokar M, Fasciani G, Wright WE, Story MD, Wistuba II, Minna JD, Shay JW. Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1610-22. PMID 24486591 DOI: 10.1158/1078-0432.Ccr-13-2589 |
0.376 |
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| 2014 |
Song SY, DAS AK, Minna JD. Comparison between concurrent and sequential chemoradiation for non-small cell lung cancer in vitro. Oncology Letters. 7: 307-310. PMID 24396437 DOI: 10.3892/ol.2013.1707 |
0.375 |
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| 2014 |
Mayba O, Gnad F, Peyton M, Zhang F, Walter K, Du P, Huntley MA, Jiang Z, Liu J, Haverty PM, Gentleman RC, Li R, Minna JD, Li Y, Shames DS, et al. Integrative analysis of two cell lines derived from a non-small-lung cancer patient--a panomics approach. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 75-86. PMID 24297535 |
0.371 |
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| 2014 |
Grant JL, Fishbein MC, Hong LS, Krysan K, Minna JD, Shay JW, Walser TC, Dubinett SM. A novel molecular pathway for Snail-dependent, SPARC-mediated invasion in non-small cell lung cancer pathogenesis. Cancer Prevention Research (Philadelphia, Pa.). 7: 150-60. PMID 24253315 DOI: 10.1158/1940-6207.Capr-13-0263 |
0.326 |
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| 2014 |
Du L, Zhao Z, Ma X, Hsiao TH, Chen Y, Young E, Suraokar M, Wistuba I, Minna JD, Pertsemlidis A. miR-93-directed downregulation of DAB2 defines a novel oncogenic pathway in lung cancer. Oncogene. 33: 4307-15. PMID 24037530 DOI: 10.1038/Onc.2013.381 |
0.368 |
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| 2014 |
Chen P, Cai L, Kim HS, Britt R, Xiao G, White MA, Minna JD, DeBerardinis RJ. Metabolic diversity in human non-small cell lung cancer Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P13 |
0.391 |
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| 2014 |
Park SJ, Walser TC, Perdomo C, Wang T, Hong L, Pagano PC, Liclican EL, Krysan K, Larsen JE, Fishbein MC, Minna JD, Lenburg ME, Spira A, Dubinett SM. Abstract 932: The impact of e-cigarette exposure on pulmonary epithelium gene expression and transformation Cancer Research. 74: 932-932. DOI: 10.1158/1538-7445.Am2014-932 |
0.333 |
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| 2014 |
Tagal V, Wei S, Zhang W, Posner BA, Minna JD, Gazdar AF, Roth MG. Abstract 573: BRG1-inactivating mutations as potential predictive markers for Aurora kinase A-targeted therapies in non-small cell lung cancers (NSCLCs) Cancer Research. 74: 573-573. DOI: 10.1158/1538-7445.Am2014-573 |
0.411 |
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| 2014 |
Zhao Z, Ma X, Yu X, Hsiao T, Chen Y, Suraokar M, Wistuba I, Minna JD, Pertsemlidis A, Du L. Abstract 466: LMO1 is a novel oncogene in neuroendocrine lung cancer Cancer Research. 74: 466-466. DOI: 10.1158/1538-7445.Am2014-466 |
0.46 |
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| 2014 |
Tian H, Lu J, Shao C, Huffman K, Carstens R, Minna JD, Hofmann SL. Abstract 4619: Protein palmitoylation in non-small cell lung cancer (NSCLC): DHHC5 palmitoyltransferase as a potential therapeutic target Cancer Research. 74: 4619-4619. DOI: 10.1158/1538-7445.Am2014-4619 |
0.392 |
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| 2014 |
Pozo K, Hillmann A, Augustyn A, Singh T, Plattner F, Minna J, Chen H, Cote GJ, Bibb JA, Nwariaku FE. Abstract 3923: Molecular characterization of an animal model for neuroendocrine thyroid cancer Cancer Research. 74: 3923-3923. DOI: 10.1158/1538-7445.Am2014-3923 |
0.32 |
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| 2014 |
Zhang Y, Ma X, Fujimoto J, Wistuba I, Lam S, Stastny V, Gao B, Larsen J, Liu X, Minna JD, Zhang MQ, Gazdar AF. Abstract 1855: SCT methylation is a potential cancer biomarker for lung cancer Cancer Research. 74: 1855-1855. DOI: 10.1158/1538-7445.Am2014-1855 |
0.443 |
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| 2014 |
Larsen JE, Davis CF, Huffman K, Girard L, Wheeler DA, Gibbs RA, Minna JD. Abstract 1525: Exome sequencing to identify permissive mutations representing acquired vulnerabilities in lung cancer Cancer Research. 74: 1525-1525. DOI: 10.1158/1538-7445.Am2014-1525 |
0.376 |
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| 2014 |
Minna JD, Gazdar A, Augustyn A, Britt R, Carstens R, Dospoy P, Gao B, Girard L, Hight S, Huffman K, Larsen J, Peyton M, Shao C, Mangelsdorf D, Brekken R, et al. Abstract IA21: Developing a new functional classification of lung cancer based on tumor acquired vulnerabilities. Clinical Cancer Research. 20: IA21-IA21. DOI: 10.1158/1078-0432.14Aacriaslc-Ia21 |
0.483 |
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| 2014 |
Taguchi A, Taylor AD, Rodriguez J, Celiktas M, Liu H, Ma X, Zhang Q, Wong C, Chin A, Girard L, Behrens C, Lam W, Lam S, Minna JD, Wistuba II, et al. Abstract B24: A systematic search for cancer/testis antigens in lung cancer identifies VCX/Y genes expanding the repertoire of potential immunotherapeutic targets. Clinical Cancer Research. 20: B24-B24. DOI: 10.1158/1078-0432.14AACRIASLC-B24 |
0.359 |
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| 2014 |
Pagano PC, Sharma S, O'Byrne S, Tse HT, Park SJ, Liclican EL, Krysan K, Walser TC, Larsen JE, Minna JD, Gimzewski JK, Carlo DD, Dubinett SM. Abstract B15: Cell motility and deformability in the pathogenesis of lung cancer. Clinical Cancer Research. 20: B15-B15. DOI: 10.1158/1078-0432.14Aacriaslc-B15 |
0.429 |
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| 2014 |
Larsen JE, Govindan R, Minna JD. Molecular Basis of Lung Cancer The Molecular Basis of Cancer: Fourth Edition. DOI: 10.1016/B978-1-4557-4066-6.00032-9 |
0.384 |
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| 2013 |
Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, ... ... Minna JD, et al. Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Cell. 155: 552-66. PMID 24243015 DOI: 10.1016/J.Cell.2013.09.041 |
0.384 |
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| 2013 |
Cooper WA, Lam DC, O'Toole SA, Minna JD. Molecular biology of lung cancer. Journal of Thoracic Disease. 5: S479-90. PMID 24163741 DOI: 10.3978/j.issn.2072-1439.2013.08.03 |
0.421 |
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| 2013 |
Meng J, Majidi M, Fang B, Ji L, Bekele BN, Minna JD, Roth JA. The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner. Plos One. 8: e77067. PMID 24146957 DOI: 10.1371/journal.pone.0077067 |
0.394 |
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| 2013 |
Lu H, Wang L, Gao W, Meng J, Dai B, Wu S, Minna J, Roth JA, Hofstetter WL, Swisher SG, Fang B. IGFBP2/FAK pathway is causally associated with dasatinib resistance in non-small cell lung cancer cells. Molecular Cancer Therapeutics. 12: 2864-73. PMID 24130049 DOI: 10.1158/1535-7163.MCT-13-0233 |
0.416 |
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| 2013 |
Cardnell RJ, Feng Y, Diao L, Fan YH, Masrorpour F, Wang J, Shen Y, Mills GB, Minna JD, Heymach JV, Byers LA. Proteomic markers of DNA repair and PI3K pathway activation predict response to the PARP inhibitor BMN 673 in small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6322-8. PMID 24077350 DOI: 10.1158/1078-0432.Ccr-13-1975 |
0.334 |
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| 2013 |
Osborne JK, Larsen JE, Gonzales JX, Shames DS, Sato M, Wistuba II, Girard L, Minna JD, Cobb MH. NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition. Oncogenesis. 2: e63. PMID 23958853 DOI: 10.1038/oncsis.2013.24 |
0.348 |
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| 2013 |
Dai B, Yoo SY, Bartholomeusz G, Graham RA, Majidi M, Yan S, Meng J, Ji L, Coombes K, Minna JD, Fang B, Roth JA. KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancer. Cancer Research. 73: 5532-43. PMID 23824739 DOI: 10.1158/0008-5472.CAN-13-0712 |
0.324 |
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| 2013 |
Osborne JK, Larsen JE, Shields MD, Gonzales JX, Shames DS, Sato M, Kulkarni A, Wistuba II, Girard L, Minna JD, Cobb MH. NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM. Proceedings of the National Academy of Sciences of the United States of America. 110: 6524-9. PMID 23553831 DOI: 10.1073/pnas.1303932110 |
0.385 |
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| 2013 |
Sato M, Larsen JE, Lee W, Sun H, Shames DS, Dalvi MP, Ramirez RD, Tang H, DiMaio JM, Gao B, Xie Y, Wistuba II, Gazdar AF, Shay JW, Minna JD. Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations. Molecular Cancer Research : McR. 11: 638-50. PMID 23449933 DOI: 10.1158/1541-7786.Mcr-12-0634-T |
0.348 |
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| 2013 |
Tang H, Xiao G, Behrens C, Schiller J, Allen J, Chow CW, Suraokar M, Corvalan A, Mao J, White MA, Wistuba II, Minna JD, Xie Y. A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1577-86. PMID 23357979 DOI: 10.1158/1078-0432.Ccr-12-2321 |
0.378 |
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| 2013 |
Yoshida K, Sato M, Hase T, Elshazley M, Yamashita R, Usami N, Taniguchi T, Yokoi K, Nakamura S, Kondo M, Girard L, Minna JD, Hasegawa Y. TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival. Cancer Science. 104: 171-7. PMID 23173913 DOI: 10.1111/cas.12068 |
0.472 |
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| 2013 |
Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, ... ... Minna JD, et al. An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 279-90. PMID 23091115 DOI: 10.1158/1078-0432.Ccr-12-1558 |
0.354 |
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| 2013 |
Sunaga N, Kaira K, Imai H, Shimizu K, Nakano T, Shames DS, Girard L, Soh J, Sato M, Iwasaki Y, Ishizuka T, Gazdar AF, Minna JD, Mori M. Oncogenic KRAS-induced epiregulin overexpression contributes to aggressive phenotype and is a promising therapeutic target in non-small-cell lung cancer. Oncogene. 32: 4034-42. PMID 22964644 DOI: 10.1038/onc.2012.402 |
0.37 |
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| 2013 |
Cooper WA, Lam DCL, O'Toole SA, Minna JD. Molecular biology of lung cancer Journal of Thoracic Disease. 5: S479-S490. DOI: 10.3978/j.issn.2072-1439.2013.08.03 |
0.421 |
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| 2013 |
Kris MG, Oxnard GR, Johnson BE, Berry LD, Chen H, Kwiatkowski DJ, Iafrate AJ, Wistuba II, Franklin WA, Aisner D, Sequist LV, Khuri FR, Garon EB, Pao W, Rudin CM, ... ... Minna JD, et al. Incidence, characteristics, and survival of patients with EGFR-mutant lung cancers with EGFR T790M at diagnosis identified in the lung cancer mutation consortium (LCMC). Journal of Clinical Oncology. 31: 8085-8085. DOI: 10.1200/Jco.2013.31.15_Suppl.8085 |
0.311 |
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| 2013 |
Johnson BE, Kris MG, Berry LD, Kwiatkowski DJ, Iafrate AJ, Varella-Garcia M, Wistuba II, Franklin WA, Ladanyi M, Su P, Sequist LV, Khuri FR, Garon EB, Pao W, Rudin CM, ... ... Minna JD, et al. A multicenter effort to identify driver mutations and employ targeted therapy in patients with lung adenocarcinomas: The Lung Cancer Mutation Consortium (LCMC). Journal of Clinical Oncology. 31: 8019-8019. DOI: 10.1200/Jco.2013.31.15_Suppl.8019 |
0.322 |
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| 2013 |
Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, Brabander JD, Komurov K, Posner BA, ... ... Minna JD, et al. Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C16 |
0.413 |
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| 2013 |
Girard L, Peyton M, Wistuba I, Xie Y, Greer R, Suraokar MB, Behrens C, Xiao G, Heymach J, Wheeler DA, Davis CF, Huffman K, Shames DS, Coombes KR, Gazdar AF, ... ... Minna JD, et al. Abstract 5589: Molecular signatures of in vitro drug response in lung cancer. Cancer Research. 73: 5589-5589. DOI: 10.1158/1538-7445.Am2013-5589 |
0.382 |
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| 2013 |
Deb D, Rajaram S, Larsen J, Minna J, Wu L, Altschuler S. Abstract 5226: Understanding single cell variability in oncogene induced pathway aberration in lung cancer. Cancer Research. 73: 5226-5226. DOI: 10.1158/1538-7445.Am2013-5226 |
0.338 |
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| 2013 |
Pu X, Skinner HD, Ye Y, Hildebrandt MA, Chang JY, Lu C, Komaki R, Minna JD, Roth JA, Wu X. Abstract 4582: Genome-wide association study of toxicity following definitive radiotherapy in non-small cell lung cancer patients. Epidemiology. 73: 4582-4582. DOI: 10.1158/1538-7445.Am2013-4582 |
0.388 |
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| 2013 |
Pu X, Wang L, Hildebrandt MA, Ye Y, Chang JY, Lu C, Skinner HD, Niu N, Jenkins GD, Komaki R, Minna JD, Roth JA, Weinshilboum RM, Wu X. Abstract 3626: Inflammation-related genetic variants predict radiation-induced toxicity following definitive radiotherapy for non-small cell lung cancer. Cancer Research. 73: 3626-3626. DOI: 10.1158/1538-7445.Am2013-3626 |
0.306 |
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| 2013 |
Cardnell RJ, Feng Y, Diao L, Fan YH, Wang J, Shin Y, Minna JD, Heymach JV, Byers LA. Abstract 2489: Proteomic profiling identifies PI3K and DNA repair pathways as potential markers of response to PARP inhibitor BMN673 in SCLC. Cancer Research. 73: 2489-2489. DOI: 10.1158/1538-7445.Am2013-2489 |
0.308 |
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| 2013 |
Carstens R, Huffman K, Wei S, Girard L, Xie Y, Hofmann S, Wistuba I, Fuqua S, Posner B, Gazdar AF, Kliewer S, O'Malley B, Mangelsdorf D, Minna JD. Abstract 1474: An RNAi-based functional classification of lung cancer reveals recurring subgroups strongly correlated with EMT status. Cancer Research. 73: 1474-1474. DOI: 10.1158/1538-7445.Am2013-1474 |
0.413 |
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| 2013 |
Li R, Walser TC, Krysan K, Shackelford D, Larsen JE, Minna JD, Dubinett SM. Abstract C296: The contribution of LKB1/STK11-mediated CXCL8 dysregulation to lung carcinogenesis. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C296 |
0.435 |
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| 2013 |
Augustyn A, Borromeo M, Wang T, Shao C, Dospoy P, Huffman K, Carstens R, Girard L, Behrens C, Wistuba I, Xie Y, Johnson J, Gazdar A, Minna J. Abstract A24: Targeted synthetic lethal screens to identify acquired vulnerabilities in a novel class of ASCL1-dependent neuroendocrine non-small cell lung cancers Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A24 |
0.463 |
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| 2012 |
Liu J, Lee W, Jiang Z, Chen Z, Jhunjhunwala S, Haverty PM, Gnad F, Guan Y, Gilbert HN, Stinson J, Klijn C, Guillory J, Bhatt D, Vartanian S, Walter K, ... ... Minna JD, et al. Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events. Genome Research. 22: 2315-27. PMID 23033341 DOI: 10.1101/Gr.140988.112 |
0.437 |
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| 2012 |
Byers LA, Wang J, Nilsson MB, Fujimoto J, Saintigny P, Yordy J, Giri U, Peyton M, Fan YH, Diao L, Masrorpour F, Shen L, Liu W, Duchemann B, Tumula P, ... ... Minna JD, et al. Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1. Cancer Discovery. 2: 798-811. PMID 22961666 DOI: 10.1158/2159-8290.Cd-12-0112 |
0.361 |
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| 2012 |
Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, Bergbower EA, Guan Y, Shin J, Guillory J, Rivers CS, Foo CK, Bhatt D, Stinson J, Gnad F, ... ... Minna JD, et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nature Genetics. 44: 1111-6. PMID 22941189 DOI: 10.1038/Ng.2405 |
0.409 |
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| 2012 |
Saintigny P, Peng S, Zhang L, Sen B, Wistuba II, Lippman SM, Girard L, Minna JD, Heymach JV, Johnson FM. Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion. Molecular Cancer Therapeutics. 11: 2021-32. PMID 22807579 DOI: 10.1158/1535-7163.Mct-12-0030 |
0.422 |
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| 2012 |
Du L, Subauste MC, DeSevo C, Zhao Z, Baker M, Borkowski R, Schageman JJ, Greer R, Yang CR, Suraokar M, Wistuba II, Gazdar AF, Minna JD, Pertsemlidis A. miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. Plos One. 7: e39167. PMID 22723956 DOI: 10.1371/Journal.Pone.0039167 |
0.365 |
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| 2012 |
Jeong Y, Xie Y, Lee W, Bookout AL, Girard L, Raso G, Behrens C, Wistuba II, Gadzar AF, Minna JD, Mangelsdorf DJ. Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer. Molecular Endocrinology (Baltimore, Md.). 26: 1443-54. PMID 22700587 DOI: 10.1210/me.2011-1382 |
0.425 |
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| 2012 |
James MA, Wen W, Wang Y, Byers LA, Heymach JV, Coombes KR, Girard L, Minna J, You M. Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus. Plos One. 7: e36116. PMID 22675468 DOI: 10.1371/Journal.Pone.0036116 |
0.445 |
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| 2012 |
Lockwood WW, Wilson IM, Coe BP, Chari R, Pikor LA, Thu KL, Solis LM, Nunez MI, Behrens C, Yee J, English J, Murray N, Tsao MS, Minna JD, Gazdar AF, et al. Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development. Plos One. 7: e37775. PMID 22629454 DOI: 10.1371/journal.pone.0037775 |
0.384 |
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| 2012 |
Liu X, Guo W, Wu S, Wang L, Wang J, Dai B, Kim ES, Heymach JV, Wang M, Girard L, Minna J, Roth JA, Swisher SG, Fang B. Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells. Biochemical Pharmacology. 83: 1456-64. PMID 22387047 DOI: 10.1016/j.bcp.2012.02.010 |
0.41 |
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| 2012 |
Xie Y, Minna JD. A lung cancer molecular prognostic test ready for prime time. Lancet (London, England). 379: 785-7. PMID 22386017 DOI: 10.1016/S0140-6736(12)60154-8 |
0.346 |
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| 2012 |
Ihle NT, Byers LA, Kim ES, Saintigny P, Lee JJ, Blumenschein GR, Tsao A, Liu S, Larsen JE, Wang J, Diao L, Coombes KR, Chen L, Zhang S, Abdelmelek MF, ... ... Minna JD, et al. Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. Journal of the National Cancer Institute. 104: 228-39. PMID 22247021 DOI: 10.1093/jnci/djr523 |
0.321 |
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| 2012 |
Varella-Garcia M, Berry LD, Su P, Franklin WA, Iafrate AJ, Ladanyi M, Camidge DR, Garon EB, Haura EB, Horn L, Khuri FR, Pao W, Rudin CM, Shaw AT, Schiller JH, ... ... Minna JD, et al. ALK and MET genes in advanced lung adenocarcinomas: The Lung Cancer Mutation Consortium experience. Journal of Clinical Oncology. 30: 7589-7589. DOI: 10.1200/Jco.2012.30.15_Suppl.7589 |
0.356 |
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| 2012 |
Byers LA, Nilsson MB, Masrorpour F, Wang J, Diao L, Bhardwaj V, Welsh J, Girard L, Coombes KR, Weinstein JN, Lippman SM, Glisson BS, Minna JD, Heymach J. Investigation of PARP1 as a therapeutic target in small cell lung cancer. Journal of Clinical Oncology. 30: 7096-7096. DOI: 10.1200/Jco.2012.30.15_Suppl.7096 |
0.364 |
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| 2012 |
Du L, DeSevo C, Robert B, Michael B, Gazdar AF, Minna JD, Pertsemlidis A. Abstract B7: microRNA regulation of cell viability and drug sensitivity in lung cancer Cancer Research. 72: B7-B7. DOI: 10.1158/1538-7445.Nonrna12-B7 |
0.313 |
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| 2012 |
Liu X, Zhang W, Girard L, Gao B, Larsen J, Wistuba II, Frenkel E, Toombs J, Brekken R, Minna J, Gazdar A. Abstract LB-85: Ectopic expression of eukaryotic translation elongation factor eEF1A2 is a hallmark for human lung cancer and is associated with poor prognosis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-85 |
0.45 |
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| 2012 |
Jeong Y, Kim J, Sato M, Lee W, Kurie JM, Minna JD, Mangelsdorf DJ. Abstract LB-521: Expression profile of nuclear receptor superfamily in a lung cancer pathogenesis model Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-521 |
0.385 |
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| 2012 |
Carstens R, Huffman K, Girard L, Posner B, Erickson H, Wistuba I, Gazdar A, Kliewer S, Fuqua S, O'Malley B, Mangelsdorf D, Minna JD. Abstract 5757: A new functional classification of lung and breast cancers based on siRNA mediated knockdown of 48 NRs and 72 CoRegulators Cancer Research. 72: 5757-5757. DOI: 10.1158/1538-7445.Am2012-5757 |
0.414 |
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| 2012 |
Bhardwaj V, Likhacheva A, Byers LABA, Diao L, Allen PK, Minna JD, Ihle NT, Powis G, Das AK, Girard L, Peyton M, Yordy J, Liao Z, Ang KK, Story M, et al. Abstract 3454: Establishing role of KRAS mutation on NSCLC radio-sensitivity Cancer Research. 72: 3454-3454. DOI: 10.1158/1538-7445.Am2012-3454 |
0.375 |
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| 2012 |
Zhang W, Yao Y, Yan J, Zhang Y, Rios J, Girard L, Pertsemlidis A, Wakeland W, Xie Y, Solis LM, Wistuba II, Hanash SM, Minna JD, Gazdar AF. Abstract 2998: BRG1 (SMARCA4) protein loss has profound effects on the transcriptome of non-small cell lung cancer (NSCLC) cell lines Cancer Research. 72: 2998-2998. DOI: 10.1158/1538-7445.Am2012-2998 |
0.391 |
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| 2012 |
Gao B, Huang C, Girard L, Gazdar AF, Shay JW, Minna JD. Abstract 2342: Identification of oncogenes and tumor suppressor genes using immortalized lung bronchial epithelial cells and small airway epithelial cells Cancer Research. 72: 2342-2342. DOI: 10.1158/1538-7445.Am2012-2342 |
0.398 |
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| 2012 |
Riquelme EM, Berhens C, Suraokar M, Chow CC, Kadara H, Wistuba II, Girard L, Minna JD. Abstract 1714:EZH2HighandmiR-101Lowexpressions are associated with chemoresistance and shorter survival in patients with lung adenocarcinoma who received adjuvant chemotherapy Cancer Research. 72: 1714-1714. DOI: 10.1158/1538-7445.Am2012-1714 |
0.34 |
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| 2012 |
Augustyn A, Tan C, Sullivan JP, Huffman K, Girard L, Borromeo M, Johnson J, Wistuba I, Xie Y, Minna JD. Abstract 1309: The lineage-specific transcription factor ASCL1 defines a subtype of non-small cell lung cancer with poor prognosis Cancer Research. 72: 1309-1309. DOI: 10.1158/1538-7445.Am2012-1309 |
0.42 |
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| 2012 |
Minna JD, Shao C, Das A, Desevo C, Dospoy P, Gao B, Greer R, Hight S, Huffman K, Larsen J, Peyton M, Shields M, Sullivan JP, Sullivan L, Gerber D, et al. Abstract IA3: Lung cancer stem cells, acquired vulnerabilities, and molecular portraits: Translation to the clinic Clinical Cancer Research. 18: IA3-IA3. DOI: 10.1158/1078-0432.12Aacriaslc-Ia3 |
0.47 |
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| 2012 |
Augustyn A, Minna J, Tan C, Sullivan J, Borromeo M, Girard L, Johnson J, Behrens C, Wistuba I, Xie Y. Abstract B42: The lineage-specific transcription factor ASCL1 defines a subtype of neuroendocrine non-small cell lung cancers with poor prognosis and points to potential therapeutic targets Clinical Cancer Research. 18: B42-B42. DOI: 10.1158/1078-0432.12AACRIASLC-B42 |
0.363 |
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| 2012 |
Shao C, Sullivan JP, Girard L, Sullivan LA, Augustyn A, Xie Y, Behrens C, Wistuba I, Minna JD. Abstract A46: Identification of ALDH1A3 as an important biomarker and therapeutic target for non-small cell lung cancer (NSCLC) cancer stem cells (CSCs) Clinical Cancer Research. 18: A46-A46. DOI: 10.1158/1078-0432.12AACRIASLC-A46 |
0.386 |
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| 2012 |
Grant JL, Walser TC, Minna JD, Shay JW, Dubinett SM. Abstract A15: Snail upregulation of SPARC leads to increased invasion in models of both early-and late-stage NSCLC Clinical Cancer Research. 18: A15-A15. DOI: 10.1158/1078-0432.12Aacriaslc-A15 |
0.429 |
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| 2012 |
Gregory KB, Coombes KR, Momin A, Girard L, Byers LA, Lin S, Peyton M, Heymach JV, Minna JD, Baladandayuthapani V. Latent feature decompositions for integrative analysis of diverse high-throughput genomic data Proceedings - Ieee International Workshop On Genomic Signal Processing and Statistics. 130-134. DOI: 10.1109/GENSIPS.2012.6507746 |
0.307 |
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| 2012 |
Rudin C, Durinck S, Stawiski E, Poirier J, Modrusan Z, Bergbower E, Illei P, Varella-Garcia M, Minna J, Seshagiri S. 552 Comprehensive Genomic Profiling of Small Cell Lung Cancer Reveals SOX2 Amplification and MYCL1 Rearrangements European Journal of Cancer. 48: 170. DOI: 10.1016/S0959-8049(12)72349-3 |
0.418 |
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| 2011 |
Kris MG, Johnson BE, Kwiatkowski DJ, Iafrate AJ, Wistuba II, Aronson SL, Engelman JA, Shyr Y, Khuri FR, Rudin CM, Garon EB, Pao W, Schiller JH, Haura EB, Shirai K, ... ... Minna JD, et al. Identification of driver mutations in tumor specimens from 1,000 patients with lung adenocarcinoma: The NCI's Lung Cancer Mutation Consortium (LCMC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: CRA7506. PMID 28020340 DOI: 10.1200/jco.2011.29.15_suppl.cra7506 |
0.344 |
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| 2011 |
Kris MG, Johnson BE, Kwiatkowski DJ, Iafrate AJ, Wistuba II, Aronson SL, Engelman JA, Shyr Y, Khuri FR, Rudin CM, Garon EB, Pao W, Schiller JH, Haura EB, Shirai K, ... ... Minna JD, et al. Identification of driver mutations in tumor specimens from 1,000 patients with lung adenocarcinoma: The NCI's Lung Cancer Mutation Consortium (LCMC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: CRA7506. PMID 27937162 DOI: 10.1200/jco.2011.29.18_suppl.cra7506 |
0.323 |
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| 2011 |
Larsen JE, Cascone T, Gerber DE, Heymach JV, Minna JD. Targeted therapies for lung cancer: clinical experience and novel agents. Cancer Journal (Sudbury, Mass.). 17: 512-27. PMID 22157296 DOI: 10.1097/PPO.0b013e31823e701a |
0.384 |
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| 2011 |
Larsen JE, Minna JD. Molecular biology of lung cancer: clinical implications. Clinics in Chest Medicine. 32: 703-40. PMID 22054881 DOI: 10.1016/j.ccm.2011.08.003 |
0.399 |
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| 2011 |
Greer RM, Peyton M, Larsen JE, Girard L, Xie Y, Gazdar AF, Harran P, Wang L, Brekken RA, Wang X, Minna JD. SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner Cancer Research. 71: 7640-7648. PMID 22049529 DOI: 10.1158/0008-5472.Can-10-3947 |
0.328 |
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| 2011 |
Shay JW, Cucinotta FA, Sulzman FM, Coleman CN, Minna JD. From mice and men to earth and space: joint NASA-NCI workshop on lung cancer risk resulting from space and terrestrial radiation. Cancer Research. 71: 6926-9. PMID 21900398 DOI: 10.1158/0008-5472.Can-11-2546 |
0.33 |
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| 2011 |
Moussalli MJ, Wu Y, Zuo X, Yang XL, Wistuba II, Raso MG, Morris JS, Bowser JL, Minna JD, Lotan R, Shureiqi I. Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion. Cancer Prevention Research (Philadelphia, Pa.). 4: 1961-72. PMID 21881028 DOI: 10.1158/1940-6207.Capr-10-0280 |
0.366 |
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| 2011 |
Delgado O, Kaisani AA, Spinola M, Xie XJ, Batten KG, Minna JD, Wright WE, Shay JW. Multipotent capacity of immortalized human bronchial epithelial cells. Plos One. 6: e22023. PMID 21760947 DOI: 10.1371/Journal.Pone.0022023 |
0.361 |
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| 2011 |
Xie Y, Xiao G, Coombes KR, Behrens C, Solis LM, Raso G, Girard L, Erickson HS, Roth J, Heymach JV, Moran C, Danenberg K, Minna JD, Wistuba II. Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5705-14. PMID 21742808 DOI: 10.1158/1078-0432.Ccr-11-0196 |
0.419 |
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| 2011 |
Yang F, Tang X, Riquelme E, Behrens C, Nilsson MB, Giri U, Varella-Garcia M, Byers LA, Lin HY, Wang J, Raso MG, Girard L, Coombes K, Lee JJ, Herbst RS, ... Minna JD, et al. Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy. Cancer Research. 71: 5512-21. PMID 21724587 DOI: 10.1158/0008-5472.Can-10-2614 |
0.329 |
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| 2011 |
Hase T, Sato M, Yoshida K, Girard L, Takeyama Y, Horio M, Elshazley M, Oguri T, Sekido Y, Shames DS, Gazdar AF, Minna JD, Kondo M, Hasegawa Y. Pivotal role of epithelial cell adhesion molecule in the survival of lung cancer cells. Cancer Science. 102: 1493-500. PMID 21535318 DOI: 10.1111/j.1349-7006.2011.01973.x |
0.441 |
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| 2011 |
Gomperts BN, Spira A, Massion PP, Walser TC, Wistuba II, Minna JD, Dubinett SM. Evolving concepts in lung carcinogenesis. Seminars in Respiratory and Critical Care Medicine. 32: 32-43. PMID 21500122 DOI: 10.1055/S-0031-1272867 |
0.412 |
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| 2011 |
Wu X, Ye Y, Rosell R, Amos CI, Stewart DJ, Hildebrandt MA, Roth JA, Minna JD, Gu J, Lin J, Buch SC, Nukui T, Ramirez Serrano JL, Taron M, Cassidy A, et al. Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy. Journal of the National Cancer Institute. 103: 817-25. PMID 21483023 DOI: 10.1093/Jnci/Djr075 |
0.376 |
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| 2011 |
Sunaga N, Shames DS, Girard L, Peyton M, Larsen JE, Imai H, Soh J, Sato M, Yanagitani N, Kaira K, Xie Y, Gazdar AF, Mori M, Minna JD. Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy. Molecular Cancer Therapeutics. 10: 336-46. PMID 21306997 DOI: 10.1158/1535-7163.MCT-10-0750 |
0.412 |
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| 2011 |
Kadara H, Behrens C, Yuan P, Solis L, Liu D, Gu X, Minna JD, Lee JJ, Kim E, Hong WK, Wistuba II, Lotan R. A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1490-501. PMID 21163870 DOI: 10.1158/1078-0432.Ccr-10-2703 |
0.403 |
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| 2011 |
Keith RL, Wilson DO, Bunn PA, Miller YE, Blatchford PJ, Jackson MK, Kittelson JK, Franklin WA, Hirsch FR, Minna J, Mao J, Massion P. Abstract PL04-02: Oral iloprost for the chemoprevention of lung cancer: A multicenter, SPORE-initiated trial Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-Pl04-02 |
0.31 |
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| 2011 |
Yao Y, Zhang Y, Taguchi A, Zhang W, Valencia I, Shames D, Wistuba I, Zhou Q, Hanash S, Thu K, Huntsman D, Lam W, Minna J, Gazdar A. Abstract LB-130: Abnormal expression of SWI/SNF chromatin remodeling complex genes in lung cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-130 |
0.433 |
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| 2011 |
Du L, Subauste MC, Baker M, DeSevo C, Borkowski R, Zhong S, Schageman JJ, Greer R, Yang C, Girard L, Gazdar AF, Wistuba II, Minna JD, Pertsemlidis A. Abstract 4709: miR-337-3p and its targets STAT3 and RAP1A modulate paclitaxel sensitivity in non-small cell lung cancers (NSCLCs) Cellular and Molecular Biology. 71: 4709-4709. DOI: 10.1158/1538-7445.Am2011-4709 |
0.333 |
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| 2011 |
Frink RE, Girard L, Wright WE, Shay JW, Minna JD. Abstract 4513: Predicting response of non-small cell lung cancer to the telomerase inhibitor imetelstat Cancer Research. 71: 4513-4513. DOI: 10.1158/1538-7445.Am2011-4513 |
0.361 |
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| 2011 |
Borkowski R, Du L, Minna JD, Gazdar AF, Pertsemlidis A. Abstract 3958: A miRNA inhibitor screen for synthetic lethal interactions in KRAS-driven NSCLC Cancer Research. 71: 3958-3958. DOI: 10.1158/1538-7445.Am2011-3958 |
0.324 |
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| 2011 |
Konstantinidou G, Torti F, Batten K, Minna JD, Shay JW, Scaglioni PP. Abstract 3850: CDKN2a deficiency exposes a requirement for RhoA in maintenance of non-small cell lung cancer Cancer Research. 71: 3850-3850. DOI: 10.1158/1538-7445.Am2011-3850 |
0.376 |
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| 2011 |
Jeong Y, Xie Y, Xiao G, Girard L, Lee W, Behrens C, Wistuba II, Minna JD, Mangelsdorf DJ. Abstract 354: Nuclear receptor expression atlas: A theragnostic targets for lung cancer patients Cancer Research. 71: 354-354. DOI: 10.1158/1538-7445.Am2011-354 |
0.438 |
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| 2011 |
Larsen JE, Sato M, Sullivan JP, Girard L, Shay JW, Minna JD. Abstract 3419: Defining the role of ZEB1 in the molecular pathogenesis of lung cancer Cancer Research. 71: 3419-3419. DOI: 10.1158/1538-7445.Am2011-3419 |
0.473 |
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| 2011 |
Yao Y, Wu Z, Wu H, Wang J, Girard L, Minna J, Gazdar A, Zhou Q. Abstract 3165: Profiling of circulating tumor-associated autoantibodies for lung adenocarcinoma detection Cancer Research. 71: 3165-3165. DOI: 10.1158/1538-7445.Am2011-3165 |
0.424 |
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| 2011 |
Johnson B, Kris M, Kwiatkowski D, Wistuba I, Engelman J, Pao W, Rudin C, Berry L, Minna J, Bunn P. 9018 POSTER DISCUSSION Identification of Driver Mutations in Tumour Specimens From 1000 Patients With Lung Adenocarcinoma for the Lung Cancer Mutation Consortium (LCMC) European Journal of Cancer. 47: S597. DOI: 10.1016/S0959-8049(11)72330-9 |
0.349 |
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| 2011 |
Wilson IM, Lockwood WW, Coe BP, Chari R, Pikor LA, Thu KL, Yee J, English J, Murray N, Tsao M, Minna JD, Gazdar AF, MacAulay CE, Lam S, Lam WL. Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development Cancer Genetics. 204: 475. DOI: 10.1016/J.CANCERGEN.2011.08.014 |
0.369 |
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| 2010 |
Jeong Y, Xie Y, Xiao G, Behrens C, Girard L, Wistuba II, Minna JD, Mangelsdorf DJ. Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer. Plos Medicine. 7: e1000378. PMID 21179495 DOI: 10.1371/Journal.Pmed.1000378 |
0.384 |
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| 2010 |
Gerber DE, Minna JD. ALK inhibition for non-small cell lung cancer: from discovery to therapy in record time. Cancer Cell. 18: 548-51. PMID 21156280 DOI: 10.1016/j.ccr.2010.11.033 |
0.43 |
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| 2010 |
Meng J, Dai B, Fang B, Bekele BN, Bornmann WG, Sun D, Peng Z, Herbst RS, Papadimitrakopoulou V, Minna JD, Peyton M, Roth JA. Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo. Plos One. 5: e14124. PMID 21124782 DOI: 10.1371/Journal.Pone.0014124 |
0.402 |
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| 2010 |
Nanjundan M, Byers LA, Carey MS, Siwak DR, Raso MG, Diao L, Wang J, Coombes KR, Roth JA, Mills GB, Wistuba II, Minna JD, Heymach JV. Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: 1894-904. PMID 21124077 DOI: 10.1097/Jto.0B013E3181F2A266 |
0.351 |
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| 2010 |
Sullivan JP, Spinola M, Dodge M, Raso MG, Behrens C, Gao B, Schuster K, Shao C, Larsen JE, Sullivan LA, Honorio S, Xie Y, Scaglioni PP, DiMaio JM, Gazdar AF, ... ... Minna JD, et al. Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling. Cancer Research. 70: 9937-48. PMID 21118965 DOI: 10.1158/0008-5472.Can-10-0881 |
0.44 |
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| 2010 |
Patz EF, Caporaso NE, Dubinett SM, Massion PP, Hirsch FR, Minna JD, Gatsonis C, Duan F, Adams A, Apgar C, Medina RM, Aberle DR. National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of specimens for validation of lung cancer biomarkers. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: 1502-6. PMID 20871260 DOI: 10.1097/Jto.0B013E3181F1C634 |
0.374 |
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| 2010 |
Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, ... ... Minna JD, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/Nbt0910-904 |
0.314 |
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| 2010 |
Xie Y, Minna JD. Non-small-cell lung cancer mRNA expression signature predicting response to adjuvant chemotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 4404-7. PMID 20823415 DOI: 10.1200/JCO.2010.31.0144 |
0.375 |
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| 2010 |
Das AK, Bell MH, Nirodi CS, Story MD, Minna JD. Radiogenomics predicting tumor responses to radiotherapy in lung cancer. Seminars in Radiation Oncology. 20: 149-55. PMID 20685577 DOI: 10.1016/j.semradonc.2010.01.002 |
0.398 |
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| 2010 |
Gazdar AF, Girard L, Lockwood WW, Lam WL, Minna JD. Lung cancer cell lines as tools for biomedical discovery and research Journal of the National Cancer Institute. 102: 1310-1321. PMID 20679594 DOI: 10.1093/jnci/djq279 |
0.444 |
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| 2010 |
Lockwood WW, Chari R, Coe BP, Thu KL, Garnis C, Malloff CA, Campbell J, Williams AC, Hwang D, Zhu CQ, Buys TP, Yee J, English JC, Macaulay C, Tsao MS, ... ... Minna JD, et al. Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. Plos Medicine. 7: e1000315. PMID 20668658 DOI: 10.1371/Journal.Pmed.1000315 |
0.452 |
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| 2010 |
Cai D, Shames DS, Raso MG, Xie Y, Kim YH, Pollack JR, Girard L, Sullivan JP, Gao B, Peyton M, Nanjundan M, Byers L, Heymach J, Mills G, Gazdar AF, ... ... Minna JD, et al. Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. Cancer Research. 70: 6477-85. PMID 20663904 DOI: 10.1158/0008-5472.Can-10-0005 |
0.464 |
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| 2010 |
Du L, Schageman JJ, Irnov, Girard L, Hammond SM, Minna JD, Gazdar AF, Pertsemlidis A. MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs. Journal of Experimental & Clinical Cancer Research : Cr. 29: 75. PMID 20624269 DOI: 10.1186/1756-9966-29-75 |
0.325 |
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| 2010 |
Sullivan JP, Minna JD. Tumor oncogenotypes and lung cancer stem cell identity. Cell Stem Cell. 7: 2-4. PMID 20621039 DOI: 10.1016/j.stem.2010.06.005 |
0.365 |
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| 2010 |
Solis LM, Behrens C, Dong W, Suraokar M, Ozburn NC, Moran CA, Corvalan AH, Biswal S, Swisher SG, Bekele BN, Minna JD, Stewart DJ, Wistuba II. Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3743-53. PMID 20534738 DOI: 10.1158/1078-0432.Ccr-09-3352 |
0.411 |
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| 2010 |
Benedettini E, Sholl LM, Peyton M, Reilly J, Ware C, Davis L, Vena N, Bailey D, Yeap BY, Fiorentino M, Ligon AH, Pan BS, Richon V, Minna JD, Gazdar AF, et al. Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis. The American Journal of Pathology. 177: 415-23. PMID 20489150 DOI: 10.2353/ajpath.2010.090863 |
0.333 |
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| 2010 |
Takeyama Y, Sato M, Horio M, Hase T, Yoshida K, Yokoyama T, Nakashima H, Hashimoto N, Sekido Y, Gazdar AF, Minna JD, Kondo M, Hasegawa Y. Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells. Cancer Letters. 296: 216-24. PMID 20452118 DOI: 10.1016/j.canlet.2010.04.008 |
0.4 |
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| 2010 |
Liu P, Yang P, Wu X, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, ... Minna J, et al. A second genetic variant on chromosome 15q24-25.1 associates with lung cancer. Cancer Research. 70: 3128-35. PMID 20395203 DOI: 10.1158/0008-5472.Can-09-3583 |
0.309 |
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| 2010 |
Imai H, Sunaga N, Shimizu Y, Kakegawa S, Shimizu K, Sano T, Ishizuka T, Oyama T, Saito R, Minna JD, Mori M. Clinicopathological and therapeutic significance of CXCL12 expression in lung cancer. International Journal of Immunopathology and Pharmacology. 23: 153-64. PMID 20378003 DOI: 10.1177/039463201002300114 |
0.47 |
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| 2010 |
Spinola M, Falvella FS, Colombo F, Sullivan JP, Shames DS, Girard L, Spessotto P, Minna JD, Dragani TA. MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment. Molecular Cancer. 9: 62. PMID 20236515 DOI: 10.1186/1476-4598-9-62 |
0.375 |
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| 2010 |
Yuan P, Kadara H, Behrens C, Tang X, Woods D, Solis LM, Huang J, Spinola M, Dong W, Yin G, Fujimoto J, Kim E, Xie Y, Girard L, Moran C, ... ... Minna JD, et al. Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. Plos One. 5: e9112. PMID 20161759 DOI: 10.1371/Journal.Pone.0009112 |
0.433 |
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| 2010 |
Xu L, Nilsson MB, Saintigny P, Cascone T, Herynk MH, Du Z, Nikolinakos PG, Yang Y, Prudkin L, Liu D, Lee JJ, Johnson FM, Wong KK, Girard L, Gazdar AF, ... Minna JD, et al. Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells. Oncogene. 29: 2616-27. PMID 20154724 DOI: 10.1038/Onc.2010.16 |
0.33 |
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| 2010 |
Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, et al. Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 517-24. PMID 20142248 DOI: 10.1158/1055-9965.Epi-09-0791 |
0.332 |
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| 2010 |
Sullivan JP, Minna JD, Shay JW. Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy. Cancer Metastasis Reviews. 29: 61-72. PMID 20094757 DOI: 10.1007/S10555-010-9216-5 |
0.348 |
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| 2010 |
Gazdar AF, Gao B, Minna JD. Lung cancer cell lines: Useless artifacts or invaluable tools for medical science? Lung Cancer (Amsterdam, Netherlands). 68: 309-18. PMID 20079948 DOI: 10.1016/j.lungcan.2009.12.005 |
0.347 |
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| 2010 |
Kohno T, Otsuka A, Girard L, Sato M, Iwakawa R, Ogiwara H, Sanchez-Cespedes M, Minna JD, Yokota J. A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene. Genes, Chromosomes & Cancer. 49: 342-52. PMID 20073072 DOI: 10.1002/gcc.20746 |
0.454 |
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| 2010 |
Pleasance ED, Stephens PJ, O'Meara S, McBride DJ, Meynert A, Jones D, Lin ML, Beare D, Lau KW, Greenman C, Varela I, Nik-Zainal S, Davies HR, Ordoñez GR, Mudie LJ, ... ... Minna JD, et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature. 463: 184-90. PMID 20016488 DOI: 10.1038/Nature08629 |
0.318 |
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| 2010 |
Colombo F, Spinola M, Falvella FS, Sullivan JP, Shames DS, Girard L, Spessotto P, Minna JD, Dragani TA. MFSD2A is a novel lung tumour suppressor gene whose expression is modulated by a 5’-region polymorphism Bmc Proceedings. 4. DOI: 10.1186/1753-6561-4-S2-P55 |
0.302 |
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| 2010 |
Walser TC, Krysan K, Gardner BK, Hong L, Fishbein MC, Goodglick L, Ooi A, Gomperts BN, Larsen JE, Minna JD, Dubinett SM. Abstract CN12-03: The inflammation-EMT-cancer initiating cell axis in the pathogenesis of lung cancer: Breaking ground in the pursuit of targeted chemoprevention Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn12-03 |
0.429 |
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| 2010 |
Hazra S, Gardner BK, Krysan K, Walser TC, Larsen JE, Pertsemlidis A, Shay JW, Minna JD, Spira A, Dubinett SM. Abstract A31: The role of microRNA 125a‐3P in the pathogenesis of lung cancer Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-A31 |
0.392 |
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| 2010 |
Grant JL, Walser TC, Yanagawa J, Lee G, Minna JD, Prasad S, Hazra S, Dubinett SM. Abstract 5592: Lovastatin and low dose celecoxib decrease proliferation and inflammation in a cellular model of lung pre-malignancy Cancer Research. 70: 5592-5592. DOI: 10.1158/1538-7445.Am10-5592 |
0.358 |
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| 2010 |
Yuan P, Kadara H, Behrens C, Tang X, Woods D, Solis LM, Huang J, Spinola M, Dong W, Yin G, Fujimoto J, Kim E, Xie Y, Girard L, Moran C, ... ... Minna JD, et al. Abstract 5166: Sex determining region Y-box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung Cancer Research. 70: 5166-5166. DOI: 10.1158/1538-7445.Am10-5166 |
0.437 |
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| 2010 |
Frink RE, Peyton M, Sullivan JP, Wright WE, Schiller J, Shay JW, Minna JD. Abstract 3577: Sensitivity and resistance of non-small cell lung cancer to the telomerase inhibitor imetelstat Cancer Research. 70: 3577-3577. DOI: 10.1158/1538-7445.Am10-3577 |
0.36 |
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| 2010 |
Greer RM, Peyton M, Girard L, Xie Y, Gazdar AF, Harran P, Wang L, Brekken RA, Wang X, Minna JD. Abstract 3479: SMAC mimetic (JP1201) sensitizes non small cell lung cancers (NSCLCs) to multiple chemotherapy agents and erlotinib in an IAP dependent but TNFα independent manner Cancer Research. 70: 3479-3479. DOI: 10.1158/1538-7445.Am10-3479 |
0.337 |
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| 2010 |
Gao B, Huang C, Sullivan J, Raso G, Wistuba I, Shay J, Minna J. Abstract 3230: Immortalization of human small airway epithelial cells as a model for studying lung tumor transformation Cancer Research. 70: 3230-3230. DOI: 10.1158/1538-7445.Am10-3230 |
0.425 |
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| 2010 |
Larsen JE, Sato M, Sullivan JP, Girard L, Xie Y, Shay JW, Minna JD. Abstract 2362: Defining the role of ZEB1 in the molecular pathogenesis of lung cancer Cancer Research. 70: 2362-2362. DOI: 10.1158/1538-7445.Am10-2362 |
0.41 |
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| 2010 |
Zhang W, Valencia I, Yan J, Chari R, Girard L, Soh J, Tam K, Xie Y, Lam W, Minna J, Gazdar A. Abstract 1133: Inactivation of BRG1 in non-small cell lung cancer (NSCLC) cell lines Cancer Research. 70: 1133-1133. DOI: 10.1158/1538-7445.Am10-1133 |
0.369 |
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| 2010 |
Valencia I, Soh J, Yan J, Zhang W, Girard L, Tam K, Xie Y, Minna J, Gazdar A. Abstract 1121: LKB1 mutation correlates with a unique gene expression profile in NSCLC Cancer Research. 70: 1121-1121. DOI: 10.1158/1538-7445.Am10-1121 |
0.307 |
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| 2010 |
Wang J, Lin S, Yordy J, Byers L, Diao L, Weinstein J, Coombes K, Minna J, Heymach J. 609 Integrative analysis of DNA methylation and gene expression identifies a DNA methylation signature associated with erlotinib resistance in EGFR wild type non-small cell lung cancer cells Ejc Supplements. 8: 191. DOI: 10.1016/S1359-6349(10)72316-8 |
0.349 |
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| 2010 |
Byers L, Wang J, Diao L, Yordy J, Girard L, Story M, Coombes K, Weinstein J, Minna J, Heymach J. 37 An epithelial to mesenchymal transition (EMT) gene expression signature identifies Axl as an EMT marker in non-small cell lung cancer (NSCLC) and head and neck cancer (HNC) lines and predicts response to erlotinib Ejc Supplements. 8: 21. DOI: 10.1016/S1359-6349(10)71742-0 |
0.418 |
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| 2009 |
Kim YH, Kwei KA, Girard L, Salari K, Kao J, Pacyna-Gengelbach M, Wang P, Hernandez-Boussard T, Gazdar AF, Petersen I, Minna JD, Pollack JR. Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer. Oncogene. 29: 1421-30. PMID 19966867 DOI: 10.1038/Onc.2009.437 |
0.481 |
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| 2009 |
Rudin C, Minna J. Cancer stem cells. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: S1079-81. PMID 19861925 DOI: 10.1097/01.Jto.0000361758.17413.7C |
0.387 |
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| 2009 |
Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, ... ... Minna JD, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nature Genetics. 41: 1238-42. PMID 19801978 DOI: 10.1038/Ng.465 |
0.399 |
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| 2009 |
Liu Y, Liu P, Wen W, James MA, Wang Y, Bailey-Wilson JE, Amos CI, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Schwartz AG, Gazdar A, ... ... Minna J, et al. Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. Cancer Research. 69: 7844-50. PMID 19789337 DOI: 10.1158/0008-5472.Can-09-1833 |
0.457 |
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| 2009 |
Ramos AH, Dutt A, Mermel C, Perner S, Cho J, Lafargue CJ, Johnson LA, Stiedl AC, Tanaka KE, Bass AJ, Barretina J, Weir BA, Beroukhim R, Thomas RK, Minna JD, et al. Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Cancer Biology & Therapy. 8: 2042-50. PMID 19755855 DOI: 10.4161/Cbt.8.21.9764 |
0.396 |
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| 2009 |
Blanco R, Iwakawa R, Tang M, Kohno T, Angulo B, Pio R, Montuenga LM, Minna JD, Yokota J, Sanchez-Cespedes M. A gene-alteration profile of human lung cancer cell lines. Human Mutation. 30: 1199-206. PMID 19472407 DOI: 10.1002/humu.21028 |
0.472 |
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| 2009 |
Sos ML, Michel K, Zander T, Weiss J, Frommolt P, Peifer M, Li D, Ullrich R, Koker M, Fischer F, Shimamura T, Rauh D, Mermel C, Fischer S, Stückrath I, ... ... Minna JD, et al. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. The Journal of Clinical Investigation. 119: 1727-40. PMID 19451690 DOI: 10.1172/Jci37127 |
0.374 |
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| 2009 |
Ivanova MM, Mazhawidza W, Dougherty SM, Minna JD, Klinge CM. Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Molecular and Cellular Endocrinology. 305: 12-21. PMID 19433257 DOI: 10.1016/J.Mce.2009.01.021 |
0.302 |
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| 2009 |
Choi K, Ahn YH, Gibbons DL, Tran HT, Creighton CJ, Girard L, Minna JD, Qin FX, Kurie JM. Distinct biological roles for the notch ligands Jagged-1 and Jagged-2. The Journal of Biological Chemistry. 284: 17766-74. PMID 19398556 DOI: 10.1074/Jbc.M109.003111 |
0.307 |
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| 2009 |
Gazdar AF, Minna JD. Multifocal lung cancers--clonality vs field cancerization and does it matter? Journal of the National Cancer Institute. 101: 541-3. PMID 19351914 DOI: 10.1093/jnci/djp059 |
0.355 |
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| 2009 |
Sos ML, Koker M, Weir BA, Heynck S, Rabinovsky R, Zander T, Seeger JM, Weiss J, Fischer F, Frommolt P, Michel K, Peifer M, Mermel C, Girard L, Peyton M, ... ... Minna JD, et al. PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. Cancer Research. 69: 3256-61. PMID 19351834 DOI: 10.1158/0008-5472.Can-08-4055 |
0.32 |
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| 2009 |
Gandhi J, Zhang J, Xie Y, Soh J, Shigematsu H, Zhang W, Yamamoto H, Peyton M, Girard L, Lockwood WW, Lam WL, Varella-Garcia M, Minna JD, Gazdar AF. Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. Plos One. 4: e4576. PMID 19238210 DOI: 10.1371/Journal.Pone.0004576 |
0.335 |
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| 2009 |
Dowell J, Minna JD. Small-cell lung cancer: translational research enroute to therapeutic advances. Oncology (Williston Park, N.Y.). 22: 1493, 1495. PMID 19227570 |
0.401 |
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| 2009 |
Zhang W, Peyton M, Xie Y, Soh J, Minna JD, Gazdar AF, Frenkel EP. Histone deacetylase inhibitor romidepsin enhances anti-tumor effect of erlotinib in non-small cell lung cancer (NSCLC) cell lines. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 161-6. PMID 19179890 DOI: 10.1097/Jto.0B013E318194Fae7 |
0.364 |
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| 2009 |
Gazdar AF, Minna JD. Deregulated EGFR signaling during lung cancer progression: mutations, amplicons, and autocrine loops. Cancer Prevention Research (Philadelphia, Pa.). 1: 156-60. PMID 19138950 DOI: 10.1158/1940-6207.CAPR-08-0080 |
0.35 |
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| 2009 |
Kubo T, Yamamoto H, Lockwood WW, Valencia I, Soh J, Peyton M, Jida M, Otani H, Fujii T, Ouchida M, Takigawa N, Kiura K, Shimizu K, Date H, Minna JD, et al. MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors. International Journal of Cancer. 124: 1778-84. PMID 19117057 DOI: 10.1002/ijc.24150 |
0.338 |
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| 2009 |
Bell M, Das A, Xie Y, Peyton M, Girard L, Story M, Nirodi C, Gazdar A, Minna J. Defining Tumor mRNA Expression Signatures Predicting Response of Lung Cancers to Radiation Therapy International Journal of Radiation Oncology*Biology*Physics. 75: S558. DOI: 10.1016/J.IJROBP.2009.07.1275 |
0.314 |
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| 2008 |
Deus HF, Stanislaus R, Behrens C, Wistuba II, Minna JD, Garner HR, Swisher SG, Roth JA, Correa AM, Broom B, Coombes K, Almeida JS. Data driven semantic integration of translational lung cancer research at MDAnderson Cancer Center. Amia ... Annual Symposium Proceedings / Amia Symposium. Amia Symposium. 927. PMID 18999102 |
0.317 |
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| 2008 |
Castro-Rivera E, Ran S, Brekken RA, Minna JD. Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells. Cancer Research. 68: 8295-303. PMID 18922901 DOI: 10.1158/0008-5472.Can-07-6601 |
0.326 |
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| 2008 |
Shivapurkar N, Stastny V, Okumura N, Girard L, Xie Y, Prinsen C, Thunnissen FB, Wistuba II, Czerniak B, Frenkel E, Roth JA, Liloglou T, Xinarianos G, Field JK, Minna JD, et al. Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. Cancer Research. 68: 7448-56. PMID 18794132 DOI: 10.1158/0008-5472.Can-08-0565 |
0.417 |
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| 2008 |
Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, ... ... Minna J, et al. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. Journal of the National Cancer Institute. 100: 1326-30. PMID 18780872 DOI: 10.1093/Jnci/Djn268 |
0.358 |
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| 2008 |
Yamamoto H, Shigematsu H, Nomura M, Lockwood WW, Sato M, Okumura N, Soh J, Suzuki M, Wistuba II, Fong KM, Lee H, Toyooka S, Date H, Lam WL, Minna JD, et al. PIK3CA mutations and copy number gains in human lung cancers. Cancer Research. 68: 6913-21. PMID 18757405 DOI: 10.1158/0008-5472.CAN-07-5084 |
0.412 |
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| 2008 |
Xie Y, Minna JD. Predicting the future for people with lung cancer. Nature Medicine. 14: 812-3. PMID 18685594 DOI: 10.1038/nm0808-812 |
0.347 |
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| 2008 |
Einhorn LH, Bonomi P, Bunn PA, Camidge DR, Carbone DP, Choy H, Dubinett SM, Gandara DR, Gaspar LE, Govindan R, Johnson DH, Minna JD, Scagliotti G, West HJ, Herbst RS. Summary report 7th Annual Targeted Therapies of the Treatment of Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 545-55. PMID 18449013 DOI: 10.1097/Jto.0B013E318170627F |
0.32 |
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| 2008 |
Shivapurkar N, Stastny V, Xie Y, Prinsen C, Frenkel E, Czerniak B, Thunnissen FB, Minna JD, Gazdar AF. Differential methylation of a short CpG-rich sequence within exon 1 of TCF21 gene: a promising cancer biomarker assay. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 995-1000. PMID 18398044 DOI: 10.1158/1055-9965.Epi-07-2808 |
0.453 |
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| 2008 |
Lockwood WW, Chari R, Coe BP, Girard L, Macaulay C, Lam S, Gazdar AF, Minna JD, Lam WL. DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers. Oncogene. 27: 4615-24. PMID 18391978 DOI: 10.1038/onc.2008.98 |
0.375 |
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| 2008 |
Kwei KA, Kim YH, Girard L, Kao J, Pacyna-Gengelbach M, Salari K, Lee J, Choi YL, Sato M, Wang P, Hernandez-Boussard T, Gazdar AF, Petersen I, Minna JD, Pollack JR. Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer. Oncogene. 27: 3635-40. PMID 18212743 DOI: 10.1038/Sj.Onc.1211012 |
0.471 |
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| 2008 |
Jagadeeswaran R, Surawska H, Krishnaswamy S, Janamanchi V, Mackinnon AC, Seiwert TY, Loganathan S, Kanteti R, Reichman T, Nallasura V, Schwartz S, Faoro L, Wang YC, Girard L, Tretiakova MS, ... ... Minna J, et al. Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion. Cancer Research. 68: 132-42. PMID 18172305 DOI: 10.1158/0008-5472.Can-07-1998 |
0.425 |
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| 2008 |
Prudkin L, Behrens C, Liu DD, Zhou X, Ozburn NC, Bekele BN, Minna JD, Moran C, Roth JA, Ji L, Wistuba II. Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 41-7. PMID 18172250 DOI: 10.1158/1078-0432.CCR-07-1252 |
0.423 |
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| 2008 |
Walser T, Yanagawa J, Luo J, Liu M, Goodglick L, Hong L, Fishbein M, Shay J, Minna J, Dubinett S. Abstract PR-11: Snail-induced and EMT-mediated early lung cancer development: Promotion of invasion and expansion of stem cell populations Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Pr-11 |
0.314 |
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| 2008 |
Hazra S, Krysan K, Walser T, Gardner B, Lee G, Shay J, Minna J, Horvath S, Dubinett S. Abstract A136: A systems approach to the preclinical evaluation of targeted chemoprevention for lung cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-A136 |
0.406 |
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| 2007 |
Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, ... ... Minna JD, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 450: 893-8. PMID 17982442 DOI: 10.1038/Nature06358 |
0.378 |
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| 2007 |
Jayachandran G, Sazaki J, Nishizaki M, Xu K, Girard L, Minna JD, Roth JA, Ji L. Fragile histidine triad-mediated tumor suppression of lung cancer by targeting multiple components of the Ras/Rho GTPase molecular switch. Cancer Research. 67: 10379-88. PMID 17974981 DOI: 10.1158/0008-5472.CAN-07-0677 |
0.311 |
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| 2007 |
Sun S, Schiller JH, Spinola M, Minna JD. New molecularly targeted therapies for lung cancer. The Journal of Clinical Investigation. 117: 2740-50. PMID 17909619 DOI: 10.1172/JCI31809 |
0.342 |
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| 2007 |
Gorlov IP, Meyer P, Liloglou T, Myles J, Boettger MB, Cassidy A, Girard L, Minna JD, Fischer R, Duffy S, Spitz MR, Haeussinger K, Kammerer S, Cantor C, Dierkesmann R, et al. Seizure 6-like (SEZ6L) gene and risk for lung cancer. Cancer Research. 67: 8406-11. PMID 17804757 DOI: 10.1158/0008-5472.Can-06-4784 |
0.414 |
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| 2007 |
Ohtani S, Iwamaru A, Deng W, Ueda K, Wu G, Jayachandran G, Kondo S, Atkinson EN, Minna JD, Roth JA, Ji L. Tumor suppressor 101F6 and ascorbate synergistically and selectively inhibit non-small cell lung cancer growth by caspase-independent apoptosis and autophagy. Cancer Research. 67: 6293-303. PMID 17616688 DOI: 10.1158/0008-5472.CAN-06-3884 |
0.38 |
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| 2007 |
Bey EA, Bentle MS, Reinicke KE, Dong Y, Yang CR, Girard L, Minna JD, Bornmann WG, Gao J, Boothman DA. An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone Proceedings of the National Academy of Sciences of the United States of America. 104: 11832-11837. PMID 17609380 DOI: 10.1073/Pnas.0702176104 |
0.323 |
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| 2007 |
Vikis H, Sato M, James M, Wang D, Wang Y, Wang M, Jia D, Liu Y, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, ... ... Minna J, et al. EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Research. 67: 4665-70. PMID 17510392 DOI: 10.1158/0008-5472.Can-07-0217 |
0.346 |
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| 2007 |
Lin J, Sun T, Ji L, Deng W, Roth J, Minna J, Arlinghaus R. Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1. Oncogene. 26: 6989-96. PMID 17486070 DOI: 10.1038/Sj.Onc.1210500 |
0.391 |
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| 2007 |
Whitehurst AW, Bodemann BO, Cardenas J, Ferguson D, Girard L, Peyton M, Minna JD, Michnoff C, Hao W, Roth MG, Xie XJ, White MA. Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature. 446: 815-9. PMID 17429401 DOI: 10.1038/nature05697 |
0.397 |
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| 2007 |
Coyle YM, Minahjuddin AT, Hynan LS, Minna JD. An ecological study of the association of metal air pollutants with lung cancer incidence in Texas. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 1: 654-61. PMID 17409932 |
0.3 |
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| 2007 |
Sato M, Shames DS, Gazdar AF, Minna JD. A translational view of the molecular pathogenesis of lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 2: 327-43. PMID 17409807 DOI: 10.1097/01.JTO.0000263718.69320.4c |
0.464 |
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| 2007 |
Matsumoto S, Iwakawa R, Takahashi K, Kohno T, Nakanishi Y, Matsuno Y, Suzuki K, Nakamoto M, Shimizu E, Minna JD, Yokota J. Prevalence and specificity of LKB1 genetic alterations in lung cancers. Oncogene. 26: 5911-8. PMID 17384680 DOI: 10.1038/sj.onc.1210418 |
0.451 |
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| 2007 |
Deng WG, Kawashima H, Wu G, Jayachandran G, Xu K, Minna JD, Roth JA, Ji L. Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells. Cancer Research. 67: 709-17. PMID 17234782 DOI: 10.1158/0008-5472.CAN-06-3463 |
0.415 |
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| 2007 |
Wang M, Vikis HG, Wang Y, Jia D, Wang D, Bierut LJ, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, ... ... Minna J, et al. Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1. Cancer Research. 67: 93-9. PMID 17210687 DOI: 10.1158/0008-5472.Can-06-2723 |
0.368 |
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| 2007 |
Sato N, Fukui T, Taniguchi T, Yokoyama T, Kondo M, Nagasaka T, Goto Y, Gao W, Ueda Y, Yokoi K, Minna JD, Osada H, Kondo Y, Sekido Y. RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line. International Journal of Cancer. Journal International Du Cancer. 120: 543-51. PMID 17096327 DOI: 10.1002/ijc.22328 |
0.448 |
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| 2007 |
Khatlani TS, Wislez M, Sun M, Srinivas H, Iwanaga K, Ma L, Hanna AE, Liu D, Girard L, Kim YH, Pollack JR, Minna JD, Wistuba II, Kurie JM. c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells. Oncogene. 26: 2658-66. PMID 17057737 DOI: 10.1038/Sj.Onc.1210050 |
0.357 |
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| 2007 |
Takahashi K, Kohno T, Ajima R, Sasaki H, Minna JD, Fujiwara T, Tanaka N, Yokota J. Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer. International Journal of Oncology. 28: 321-8. PMID 16391785 |
0.474 |
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| 2007 |
Minna JD, Girard L, Sato M, Peyton M, Lee W, Shames D, Honorio S, Xie Y, Xie X, Lam D, Lockwood W, Lam W, Wang Y, Lam S, Kim E, et al. M10-01: Molecular pathogenesis of lung cancer with translation to the clinic Journal of Thoracic Oncology. 2: S178-S179. DOI: 10.1097/01.Jto.0000282957.22684.90 |
0.322 |
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| 2006 |
Lam DC, Girard L, Suen WS, Chung LP, Tin VP, Lam WK, Minna JD, Wong MP. Establishment and expression profiling of new lung cancer cell lines from Chinese smokers and lifetime never-smokers. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 1: 932-42. PMID 17409975 DOI: 10.1097/01243894-200611000-00003 |
0.419 |
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| 2006 |
Sekine I, Minna JD, Nishio K, Tamura T, Saijo N. A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with lung cancer Journal of Thoracic Oncology. 1: 31-37. PMID 17409824 DOI: 10.1097/01243894-200601000-00008 |
0.343 |
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| 2006 |
Suzuki M, Shigematsu H, Shames DS, Sunaga N, Takahashi T, Shivapurkar N, Iizasa T, Minna JD, Fujisawa T, Gazdar AF. Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers. Annals of Surgical Oncology. 14: 1397-404. PMID 17195088 DOI: 10.1245/s10434-006-9089-6 |
0.332 |
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| 2006 |
Shames DS, Girard L, Gao B, Sato M, Lewis CM, Shivapurkar N, Jiang A, Perou CM, Kim YH, Pollack JR, Fong KM, Lam CL, Wong M, Shyr Y, Nanda R, ... ... Minna JD, et al. A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. Plos Medicine. 3: e486. PMID 17194187 DOI: 10.1371/Journal.Pmed.0030486 |
0.413 |
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| 2006 |
Helfrich BA, Raben D, Varella-Garcia M, Gustafson D, Chan DC, Bemis L, Coldren C, Barón A, Zeng C, Franklin WA, Hirsch FR, Gazdar A, Minna J, Bunn PA. Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 7117-25. PMID 17145836 DOI: 10.1158/1078-0432.Ccr-06-0760 |
0.317 |
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| 2006 |
Ueda K, Kawashima H, Ohtani S, Deng WG, Ravoori M, Bankson J, Gao B, Girard L, Minna JD, Roth JA, Kundra V, Ji L. The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells. Cancer Research. 66: 9682-90. PMID 17018626 DOI: 10.1158/0008-5472.Can-06-1483 |
0.408 |
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| 2006 |
Das AK, Sato M, Story MD, Peyton M, Graves R, Redpath S, Girard L, Gazdar AF, Shay JW, Minna JD, Nirodi CS. Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation. Cancer Research. 66: 9601-8. PMID 17018617 DOI: 10.1158/0008-5472.Can-06-2627 |
0.32 |
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| 2006 |
Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, Yang G, Li Y, Yao W, Vaddi K, Gazdar AF, ... ... Minna JD, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 10: 39-50. PMID 16843264 DOI: 10.1016/j.ccr.2006.05.024 |
0.342 |
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| 2006 |
Coe BP, Lockwood WW, Girard L, Chari R, Macaulay C, Lam S, Gazdar AF, Minna JD, Lam WL. Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer. British Journal of Cancer. 94: 1927-35. PMID 16705311 DOI: 10.1038/sj.bjc.6603167 |
0.464 |
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| 2006 |
Suzuki M, Shigematsu H, Iizasa T, Hiroshima K, Nakatani Y, Minna JD, Gazdar AF, Fujisawa T. Exclusive mutation in epidermal growth factor receptor gene, HER-2, and KRAS, and synchronous methylation of nonsmall cell lung cancer. Cancer. 106: 2200-7. PMID 16598760 DOI: 10.1002/cncr.21853 |
0.427 |
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| 2006 |
Dowell JE, Minna JD. EGFR mutations and molecularly targeted therapy: a new era in the treatment of lung cancer. Nature Clinical Practice. Oncology. 3: 170-1. PMID 16596125 DOI: 10.1038/NCPONC0476 |
0.331 |
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| 2006 |
Tam IY, Chung LP, Suen WS, Wang E, Wong MC, Ho KK, Lam WK, Chiu SW, Girard L, Minna JD, Gazdar AF, Wong MP. Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1647-53. PMID 16533793 DOI: 10.1158/1078-0432.CCR-05-1981 |
0.347 |
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| 2006 |
Witta SE, Gemmill RM, Hirsch FR, Coldren CD, Hedman K, Ravdel L, Helfrich B, Dziadziuszko R, Chan DC, Sugita M, Chan Z, Baron A, Franklin W, Drabkin HA, Girard L, ... ... Minna JD, et al. Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. Cancer Research. 66: 944-50. PMID 16424029 DOI: 10.1158/0008-5472.Can-05-1988 |
0.327 |
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| 2006 |
Agirre X, Román-Gómez J, Vázquez I, Jiménez-Velasco A, Garate L, Montiel-Duarte C, Artieda P, Cordeu L, Lahortiga I, Calasanz MJ, Heiniger A, Torres A, Minna JD, Prósper F. Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and chronic myeloid leukemia. International Journal of Cancer. 118: 1945-53. PMID 16287063 DOI: 10.1002/ijc.21584 |
0.316 |
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| 2006 |
Heller G, Fong KM, Girard L, Seidl S, End-Pfützenreuter A, Lang G, Gazdar AF, Minna JD, Zielinski CC, Zöchbauer-Müller S. Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas. Oncogene. 25: 959-68. PMID 16205641 DOI: 10.1038/sj.onc.1209115 |
0.437 |
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| 2006 |
Tomizawa Y, Iijima H, Sunaga N, Sato K, Takise A, Otani Y, Tanaka S, Suga T, Saito R, Ishizuka T, Dobashi K, Minna JD, Nakajima T, Mori M. Clinicopathologic significance of the mutations of the epidermal growth factor receptor gene in patients with non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 6816-22. PMID 16203769 DOI: 10.1158/1078-0432.CCR-05-0441 |
0.369 |
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| 2006 |
Garnis C, Lockwood WW, Vucic E, Ge Y, Girard L, Minna JD, Gazdar AF, Lam S, MacAulay C, Lam WL. High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. International Journal of Cancer. 118: 1556-64. PMID 16187286 DOI: 10.1002/Ijc.21491 |
0.306 |
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| 2006 |
Iijima H, Tomizawa Y, Iwasaki Y, Sato K, Sunaga N, Dobashi K, Saito R, Nakajima T, Minna JD, Mori M. Genetic and epigenetic inactivation of LTF gene at 3p21.3 in lung cancers. International Journal of Cancer. 118: 797-801. PMID 16152584 DOI: 10.1002/ijc.21462 |
0.477 |
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| 2006 |
Coe BP, Lee EH, Chi B, Girard L, Minna JD, Gazdar AF, Lam S, MacAulay C, Lam WL. Gain of a region on 7p22.3, containing MAD1L1, is the most frequent event in small-cell lung cancer cell lines. Genes, Chromosomes & Cancer. 45: 11-9. PMID 16130125 DOI: 10.1002/gcc.20260 |
0.413 |
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| 2006 |
Lam DC, Girard L, Suen W, Chung L, Tin VP, Lam W, Minna JD, Wong MP. Establishment and Expression Profiling of New Lung Cancer Cell Lines from Chinese Smokers and Lifetime Never-Smokers Journal of Thoracic Oncology. 1: 932-942. DOI: 10.1016/S1556-0864(15)31624-5 |
0.377 |
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| 2006 |
Sekine I, Minna JD, Nishio K, Tamura T, Saijo N. A Literature Review of Molecular Markers Predictive of Clinical Response to Cytotoxic Chemotherapy in Patients with Lung Cancer Journal of Thoracic Oncology. 1: 31-37. DOI: 10.1016/S1556-0864(15)31510-0 |
0.315 |
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| 2005 |
Ji L, Kawashima H, Lu C, Kurie J, Chada S, Minna JD, Roth JA. Synergistic inhibition of EGFR tyrosine kinase and tumor cell growth in non-small cell lung cancer (NSCLC) by combination treatment with FUS1-nanoparticles and gefitinib. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7081. PMID 27944549 DOI: 10.1200/Jco.2005.23.16_Suppl.7081 |
0.374 |
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| 2005 |
Weir B, LaFramboise T, Lin M, Beroukhim R, Garraway L, Beheshti J, Lee J, Janne P, Li C, Sellers W, Naoki K, Richards W, Sugarbaker D, Chen F, Rubin M, ... ... Minna J, et al. High resolution SNP arrays identify amplified regions in lung cancer Cancer Biology and Therapy. 4. PMID 16710933 DOI: 10.4161/cbt.4.8.2003 |
0.319 |
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| 2005 |
Ji L, Minna JD, Roth JA. 3p21.3 tumor suppressor cluster: prospects for translational applications. Future Oncology (London, England). 1: 79-92. PMID 16555978 DOI: 10.1517/14796694.1.1.79 |
0.301 |
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| 2005 |
Fujimoto N, Wislez M, Zhang J, Iwanaga K, Dackor J, Hanna AE, Kalyankrishna S, Cody DD, Price RE, Sato M, Shay JW, Minna JD, Peyton M, Tang X, Massarelli E, et al. High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor. Cancer Research. 65: 11478-85. PMID 16357156 DOI: 10.1158/0008-5472.Can-05-1977 |
0.365 |
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| 2005 |
Dowell JE, Minna JD. The impact of epidermal-growth-factor-receptor mutations in response to lung-cancer therapy. Nature Clinical Practice. Oncology. 1: 2-3. PMID 16264773 DOI: 10.1038/ncponc0007 |
0.309 |
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| 2005 |
Suzuki M, Shigematsu H, Shames DS, Sunaga N, Takahashi T, Shivapurkar N, Iizasa T, Frenkel EP, Minna JD, Fujisawa T, Gazdar AF. DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers. British Journal of Cancer. 93: 1029-37. PMID 16234815 DOI: 10.1038/Sj.Bjc.6602837 |
0.301 |
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| 2005 |
Sato M, Takahashi K, Nagayama K, Arai Y, Ito N, Okada M, Minna JD, Yokota J, Kohno T. Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer. Genes, Chromosomes & Cancer. 44: 405-14. PMID 16114034 DOI: 10.1002/gcc.20253 |
0.383 |
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| 2005 |
Minna JD, Peyton MJ, Gazdar AF. Gefitinib versus cetuximab in lung cancer: round one. Journal of the National Cancer Institute. 97: 1168-9. PMID 16106015 DOI: 10.1093/jnci/dji247 |
0.406 |
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| 2005 |
Zhao X, Weir BA, LaFramboise T, Lin M, Beroukhim R, Garraway L, Beheshti J, Lee JC, Naoki K, Richards WG, Sugarbaker D, Chen F, Rubin MA, Jänne PA, Girard L, ... Minna J, et al. Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Research. 65: 5561-70. PMID 15994928 DOI: 10.1158/0008-5472.Can-04-4603 |
0.334 |
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| 2005 |
Minna JD, Dowell J. Erlotinib hydrochloride. Nature Reviews. Drug Discovery. S14-5. PMID 15962526 DOI: 10.1038/nrd1612 |
0.363 |
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| 2005 |
Zöchbauer-Müller S, Fong KM, Geradts J, Xu X, Seidl S, End-Pfützenreuter A, Lang G, Heller G, Zielinski CC, Gazdar AF, Minna JD. Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation. Oncogene. 24: 6249-55. PMID 15940253 DOI: 10.1038/sj.onc.1208775 |
0.447 |
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| 2005 |
Shigematsu H, Takahashi T, Nomura M, Majmudar K, Suzuki M, Lee H, Wistuba II, Fong KM, Toyooka S, Shimizu N, Fujisawa T, Minna JD, Gazdar AF. Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. Cancer Research. 65: 1642-6. PMID 15753357 DOI: 10.1158/0008-5472.CAN-04-4235 |
0.358 |
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| 2005 |
Shigematsu H, Lin L, Takahashi T, Nomura M, Suzuki M, Wistuba II, Fong KM, Lee H, Toyooka S, Shimizu N, Fujisawa T, Feng Z, Roth JA, Herz J, Minna JD, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. Journal of the National Cancer Institute. 97: 339-46. PMID 15741570 DOI: 10.1093/Jnci/Dji055 |
0.368 |
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| 2005 |
Sekine I, Sato M, Sunaga N, Toyooka S, Peyton M, Parsons R, Wang W, Gazdar AF, Minna JD. The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer. Oncogene. 24: 2735-8. PMID 15735765 DOI: 10.1038/Sj.Onc.1207694 |
0.477 |
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| 2005 |
Dowell JE, Minna JD. Chasing mutations in the epidermal growth factor in lung cancer. The New England Journal of Medicine. 352: 830-2. PMID 15728818 DOI: 10.1056/NEJME058033 |
0.34 |
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| 2005 |
Kishimoto M, Kohno T, Okudela K, Otsuka A, Sasaki H, Tanabe C, Sakiyama T, Hirama C, Kitabayashi I, Minna JD, Takenoshita S, Yokota J. Mutations and deletions of the CBP gene in human lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 512-9. PMID 15701835 |
0.38 |
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| 2005 |
Amann J, Kalyankrishna S, Massion PP, Ohm JE, Girard L, Shigematsu H, Peyton M, Juroske D, Huang Y, Stuart Salmon J, Kim YH, Pollack JR, Yanagisawa K, Gazdar A, Minna JD, et al. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. Cancer Research. 65: 226-35. PMID 15665299 |
0.314 |
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| 2005 |
Shigematsu H, Nomura M, Suzuki M, Lee H, Wistuba I, Fong K, Toyooka S, Shimizu N, Minna J, Gazdar A. O-011 Gene mutations indicate different pathways to lung cancers innever and ever smokers Lung Cancer. 49: S7-S8. DOI: 10.1016/S0169-5002(05)80143-6 |
0.342 |
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| 2004 |
Ramirez RD, Sheridan S, Girard L, Sato M, Kim Y, Pollack J, Peyton M, Zou Y, Kurie JM, Dimaio JM, Milchgrub S, Smith AL, Souza RF, Gilbey L, Zhang X, ... ... Minna JD, et al. Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Research. 64: 9027-34. PMID 15604268 DOI: 10.1158/0008-5472.Can-04-3703 |
0.416 |
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| 2004 |
Ito I, Ji L, Tanaka F, Saito Y, Gopalan B, Branch CD, Xu K, Atkinson EN, Bekele BN, Stephens LC, Minna JD, Roth JA, Ramesh R. Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo. Cancer Gene Therapy. 11: 733-9. PMID 15486560 DOI: 10.1038/sj.cgt.7700756 |
0.42 |
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| 2004 |
Gazdar AF, Shigematsu H, Herz J, Minna JD. Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers? Trends in Molecular Medicine. 10: 481-6. PMID 15464447 DOI: 10.1016/J.Molmed.2004.08.008 |
0.326 |
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| 2004 |
Li J, Wang F, Haraldson K, Protopopov A, Duh FM, Geil L, Kuzmin I, Minna JD, Stanbridge E, Braga E, Kashuba VI, Klein G, Lerman MI, Zabarovsky ER. Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C. Cancer Research. 64: 6438-43. PMID 15374952 DOI: 10.1158/0008-5472.Can-03-3869 |
0.319 |
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| 2004 |
Nishizaki M, Sasaki J, Fang B, Atkinson EN, Minna JD, Roth JA, Ji L. Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells. Cancer Research. 64: 5745-52. PMID 15313915 DOI: 10.1158/0008-5472.CAN-04-0195 |
0.367 |
|
| 2004 |
Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Wiest JS, Fain P, Schwartz AG, You M, Franklin W, Klein C, Gazdar A, Rothschild H, Mandal D, Coons T, ... ... Minna J, et al. A major lung cancer susceptibility locus maps to chromosome 6q23-25. American Journal of Human Genetics. 75: 460-74. PMID 15272417 DOI: 10.1086/423857 |
0.343 |
|
| 2004 |
Li J, Wang F, Protopopov A, Malyukova A, Kashuba V, Minna JD, Lerman MI, Klein G, Zabarovsky E. Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene. Oncogene. 23: 5941-9. PMID 15208682 DOI: 10.1038/Sj.Onc.1207789 |
0.341 |
|
| 2004 |
Senchenko VN, Liu J, Loginov W, Bazov I, Angeloni D, Seryogin Y, Ermilova V, Kazubskaya T, Garkavtseva R, Zabarovska VI, Kashuba VI, Kisselev LL, Minna JD, Lerman MI, Klein G, et al. Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung and breast carcinomas. Oncogene. 23: 5719-28. PMID 15208675 DOI: 10.1038/Sj.Onc.1207760 |
0.311 |
|
| 2004 |
Sunaga N, Miyajima K, Suzuki M, Sato M, White MA, Ramirez RD, Shay JW, Gazdar AF, Minna JD. Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer Cancer Research. 64: 4277-4285. PMID 15205342 DOI: 10.1158/0008-5472.Can-03-3941 |
0.454 |
|
| 2004 |
Minna JD, Gazdar AF, Sprang SR, Herz J. Cancer. A bull's eye for targeted lung cancer therapy. Science (New York, N.Y.). 304: 1458-61. PMID 15178790 DOI: 10.1126/Science.1099578 |
0.377 |
|
| 2004 |
Wolff NC, Randle DE, Egorin MJ, Minna JD, Ilaria RL. Imatinib mesylate efficiently achieves therapeutic intratumor concentrations in vivo but has limited activity in a xenograft model of small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3528-34. PMID 15161712 DOI: 10.1158/1078-0432.CCR-0957-03 |
0.396 |
|
| 2004 |
Suzuki M, Sunaga N, Shames DS, Toyooka S, Gazdar AF, Minna JD. RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells. Cancer Research. 64: 3137-43. PMID 15126351 DOI: 10.1158/0008-5472.CAN-03-3046 |
0.333 |
|
| 2004 |
Uno F, Sasaki J, Nishizaki M, Carboni G, Xu K, Atkinson EN, Kondo M, Minna JD, Roth JA, Ji L. Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells. Cancer Research. 64: 2969-76. PMID 15126327 |
0.395 |
|
| 2004 |
Toyooka S, Suzuki M, Tsuda T, Toyooka KO, Maruyama R, Tsukuda K, Fukuyama Y, Iizasa T, Fujisawa T, Shimizu N, Minna JD, Gazdar AF. Dose effect of smoking on aberrant methylation in non-small cell lung cancers. International Journal of Cancer. 110: 462-4. PMID 15095316 DOI: 10.1002/ijc.20125 |
0.335 |
|
| 2004 |
Jänne PA, Li C, Zhao X, Girard L, Chen TH, Minna J, Christiani DC, Johnson BE, Meyerson M. High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines. Oncogene. 23: 2716-26. PMID 15048096 DOI: 10.1038/Sj.Onc.1207329 |
0.351 |
|
| 2004 |
Zöchbauer-Müller S, Wistuba II, Minna JD, Gazdar AF. Fragile histidine triad (FHIT) gene abnormalities in lung cancer. Clinical Lung Cancer. 2: 141-5. PMID 14731325 DOI: 10.3816/CLC.2000.N.027 |
0.445 |
|
| 2004 |
Sathyanarayana UG, Toyooka S, Padar A, Takahashi T, Brambilla E, Minna JD, Gazdar AF. Epigenetic inactivation of laminin-5-encoding genes in lung cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2665-72. PMID 12855645 |
0.458 |
|
| 2003 |
Uchiyama M, Usami N, Kondo M, Mori S, Ito M, Ito G, Yoshioka H, Imaizumi M, Ueda Y, Takahashi M, Minna JD, Shimokata K, Sekido Y. Loss of heterozygosity of chromosome 12p does not correlate with KRAS mutation in non-small cell lung cancer. International Journal of Cancer. Journal International Du Cancer. 107: 962-9. PMID 14601056 DOI: 10.1002/ijc.11493 |
0.368 |
|
| 2003 |
Yamagata N, Shyr Y, Yanagisawa K, Edgerton M, Dang TP, Gonzalez A, Nadaf S, Larsen P, Roberts JR, Nesbitt JC, Jensen R, Levy S, Moore JH, Minna JD, Carbone DP. A training-testing approach to the molecular classification of resected non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4695-704. PMID 14581339 |
0.405 |
|
| 2003 |
Sato M, Girard L, Sekine I, Sunaga N, Ramirez RD, Kamibayashi C, Minna JD. Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer. Oncogene. 22: 7243-6. PMID 14562054 DOI: 10.1038/sj.onc.1206977 |
0.471 |
|
| 2003 |
Minna JD, Kurie JM, Jacks T. A big step in the study of small cell lung cancer. Cancer Cell. 4: 163-6. PMID 14522249 DOI: 10.1016/S1535-6108(03)00221-6 |
0.412 |
|
| 2003 |
Fong KM, Sekido Y, Gazdar AF, Minna JD. Lung cancer. 9: Molecular biology of lung cancer: clinical implications. Thorax. 58: 892-900. PMID 14514947 DOI: 10.1136/thorax.58.10.892 |
0.418 |
|
| 2003 |
Virmani A, Rathi A, Heda S, Sugio K, Lewis C, Tonk V, Takahashi T, Roth JA, Minna JD, Euhus DM, Gazdar AF. Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers. International Journal of Cancer. Journal International Du Cancer. 107: 341-5. PMID 14506731 DOI: 10.1002/ijc.11393 |
0.358 |
|
| 2003 |
Agathanggelou A, Bièche I, Ahmed-Choudhury J, Nicke B, Dammann R, Baksh S, Gao B, Minna JD, Downward J, Maher ER, Latif F. Identification of novel gene expression targets for the Ras association domain family 1 (RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma. Cancer Research. 63: 5344-51. PMID 14500366 |
0.423 |
|
| 2003 |
Sasaki S, Kitagawa Y, Sekido Y, Minna JD, Kuwano H, Yokota J, Kohno T. Molecular processes of chromosome 9p21 deletions in human cancers. Oncogene. 22: 3792-8. PMID 12802286 DOI: 10.1038/sj.onc.1206589 |
0.386 |
|
| 2003 |
Virmani A, Rathi A, Sugio K, Sathyanarayana UG, Toyooka S, Kischel FC, Tonk V, Padar A, Takahashi T, Roth JA, Euhus DM, Minna JD, Gazdar AF. Aberrant methylation of TMS1 in small cell, non small cell lung cancer and breast cancer. International Journal of Cancer. Journal International Du Cancer. 106: 198-204. PMID 12800194 DOI: 10.1002/ijc.11206 |
0.389 |
|
| 2003 |
Agathanggelou A, Dallol A, Zöchbauer-Müller S, Morrissey C, Honorio S, Hesson L, Martinsson T, Fong KM, Kuo MJ, Yuen PW, Maher ER, Minna JD, Latif F. Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers. Oncogene. 22: 1580-8. PMID 12629521 DOI: 10.1038/sj.onc.1206243 |
0.323 |
|
| 2003 |
Hesson L, Dallol A, Minna JD, Maher ER, Latif F. NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers. Oncogene. 22: 947-54. PMID 12584574 DOI: 10.1038/sj.onc.1206191 |
0.337 |
|
| 2003 |
Carboni GL, Gao B, Nishizaki M, Xu K, Minna JD, Roth JA, Ji L. CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity. Oncogene. 22: 615-26. PMID 12555074 DOI: 10.1038/sj.onc.1206134 |
0.322 |
|
| 2003 |
Toyooka S, Maruyama R, Toyooka KO, McLerran D, Feng Z, Fukuyama Y, Virmani AK, Zochbauer-Muller S, Tsukuda K, Sugio K, Shimizu N, Shimizu K, Lee H, Chen CY, Fong KM, ... ... Minna JD, et al. Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. International Journal of Cancer. Journal International Du Cancer. 103: 153-60. PMID 12455028 DOI: 10.1002/Ijc.10787 |
0.305 |
|
| 2003 |
Zöchbauer-Müller S, Minna JD, Gazdar AF. Aberrant DNA methylation in lung cancer: biological and clinical implications. The Oncologist. 7: 451-7. PMID 12401908 DOI: 10.1634/THEONCOLOGIST.7-5-451 |
0.4 |
|
| 2003 |
Toyooka S, Fukuyama Y, Wistuba II, Tockman MS, Minna JD, Gazdar AF. Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2292-7. PMID 12114433 |
0.433 |
|
| 2003 |
Minna JD, Fong K, Zöchbauer-Müller S, Gazdar AF. Molecular pathogenesis of lung cancer and potential translational applications. Cancer Journal (Sudbury, Mass.). S41-6. PMID 12075701 |
0.431 |
|
| 2003 |
Toyooka S, Shivapurkar N, Toyooka KO, Miyajima K, Suzuki M, Redd J, Pass HI, Roth JA, Minna JD, Gazdar AF. P-309 Aberrant methylation of the tumor necrosis factor related apoptosis inducing ligand decoy receptor genes in malignant mesothelioma and lung cancer Lung Cancer. 41: S170. DOI: 10.1016/S0169-5002(03)92277-X |
0.334 |
|
| 2003 |
Morrissey C, Toyooka S, Fong K, Dallol A, Latif F, Gazdar A, Minna JD. P-299 Epigenetic inactivation of the candidate tumor suppressor gene SLIT-2 in SCLC and NSCLC lung cancers Lung Cancer. 41: S167. DOI: 10.1016/S0169-5002(03)92267-7 |
0.417 |
|
| 2003 |
Sunaga N, Miyajima K, Suzuki M, Sato M, White MA, Gazdar AF, Minna JD. P-295 Dramatically different roles for caveolin-1 in the development of Non-Small Cell Lung Cancer (NSCLC) vs. Small Cell Lung Cancer (SCLC) Lung Cancer. 41: S166. DOI: 10.1016/S0169-5002(03)92263-X |
0.44 |
|
| 2003 |
Shigematsu H, Suzuki M, Miyajima K, Takahashi T, Sathyanarayana UG, Brambilla EM, Minna JD, Gazdar AF. P-290 Aberrant promoter hypermethylation of RUNX3 in non-small cell lung cancer confers adverse prognosis Lung Cancer. 41: S165. DOI: 10.1016/S0169-5002(03)92258-6 |
0.432 |
|
| 2003 |
Lam DC, Wong MP, Lam W, Chung L, Chiu S, Chau W, Ho K, Minna JD. O-305 Quantitative comparison of expression of nicotinic acetylcholine receptor (nAChR) subunits between non-small cell lung cancers (NSCLCs) arising in life-time never-smokers and smokers in chinese patients Lung Cancer. 41: S89. DOI: 10.1016/S0169-5002(03)91963-5 |
0.3 |
|
| 2003 |
Castro-Rivera E, Ran S, Thrope P, Minna J. O-302 Semaphorin-3B and VEGF165 exert antagonistic effects on the survival and apoptosis of non-small lung cancer cells Lung Cancer. 41: S88. DOI: 10.1016/S0169-5002(03)91960-X |
0.327 |
|
| 2003 |
Sathyanarayana UG, Shigematsu H, Suzuki M, Padar A, Miyajima K, Takahashi T, Ramirez R, Minna JD, Gazdar AF. O-175 Frequent loss of expression of tumor invasion genes integrin, TIMP4 and LN5 in lung cancer via epigenetic and non-epigenetic mechanisms Lung Cancer. 41: S52-S53. DOI: 10.1016/S0169-5002(03)91833-2 |
0.352 |
|
| 2003 |
Wistuba II, Valencia I, Madariaga J, Girard L, Minna J, Gazdar AF. E-90. Molecular pathology of small cell lung cancer Lung Cancer. 41: S109. DOI: 10.1016/S0169-5002(03)90497-1 |
0.395 |
|
| 2003 |
Roth JA, Minna JD, Ji LX, Ramesh R. E-63. New gene targets for lung cancer therapy Lung Cancer. 41: S79. DOI: 10.1016/S0169-5002(03)90470-3 |
0.337 |
|
| 2003 |
Gazdar AF, Minna JD. E-30. The hallmarks of lung cancer Lung Cancer. 41: S39. DOI: 10.1016/S0169-5002(03)90437-5 |
0.358 |
|
| 2002 |
Zhang H, Spitz MR, Tomlinson GE, Schabath MB, Minna JD, Wu X. Modification of lung cancer susceptibility by green tea extract as measured by the comet assay Cancer Detection and Prevention. 26: 411-418. PMID 12507225 DOI: 10.1016/S0361-090X(02)00127-7 |
0.335 |
|
| 2002 |
Shivapurkar N, Reddy J, Matta H, Sathyanarayana UG, Huang CX, Toyooka S, Minna JD, Chaudhary PM, Gazdar AF. Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification. Oncogene. 21: 8510-4. PMID 12466971 DOI: 10.1038/sj.onc.1205941 |
0.359 |
|
| 2002 |
Brose MS, Volpe P, Feldman M, Kumar M, Rishi I, Gerrero R, Einhorn E, Herlyn M, Minna J, Nicholson A, Roth JA, Albelda SM, Davies H, Cox C, Brignell G, et al. BRAF and RAS mutations in human lung cancer and melanoma. Cancer Research. 62: 6997-7000. PMID 12460918 |
0.319 |
|
| 2002 |
Zhu Y, Spitz MR, Strom S, Tomlinson GE, Amos CI, Minna JD, Wu X. A case-control analysis of lymphocytic chromosome 9 aberrations in lung cancer. International Journal of Cancer. Journal International Du Cancer. 102: 536-40. PMID 12432559 DOI: 10.1002/Ijc.10762 |
0.322 |
|
| 2002 |
Dallol A, Da Silva NF, Viacava P, Minna JD, Bieche I, Maher ER, Latif F. SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers. Cancer Research. 62: 5874-80. PMID 12384551 |
0.316 |
|
| 2002 |
Zabarovsky ER, Lerman MI, Minna JD. Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers. Oncogene. 21: 6915-35. PMID 12362274 DOI: 10.1038/sj.onc.1205835 |
0.436 |
|
| 2002 |
Nishioka M, Kohno T, Tani M, Yanaihara N, Tomizawa Y, Otsuka A, Sasaki S, Kobayashi K, Niki T, Maeshima A, Sekido Y, Minna JD, Sone S, Yokota J. MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 99: 12269-74. PMID 12209013 DOI: 10.1073/pnas.192445899 |
0.476 |
|
| 2002 |
Shivapurkar N, Toyooka S, Eby MT, Huang CX, Sathyanarayana UG, Cunningham HT, Reddy JL, Brambilla E, Takahashi T, Minna JD, Chaudhary PM, Gazdar AF. Differential inactivation of caspase-8 in lung cancers. Cancer Biology & Therapy. 1: 65-9. PMID 12170765 DOI: 10.4161/cbt.1.1.45 |
0.369 |
|
| 2002 |
Sato M, Horio Y, Sekido Y, Minna JD, Shimokata K, Hasegawa Y. The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines. Oncogene. 21: 4822-9. PMID 12101420 DOI: 10.1038/sj.onc.1205581 |
0.442 |
|
| 2002 |
Minna JD, Roth JA, Gazdar AF. Focus on lung cancer. Cancer Cell. 1: 49-52. PMID 12086887 DOI: 10.1016/S1535-6108(02)00027-2 |
0.396 |
|
| 2002 |
Dallol A, Forgacs E, Martinez A, Sekido Y, Walker R, Kishida T, Rabbitts P, Maher ER, Minna JD, Latif F. Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers. Oncogene. 21: 3020-8. PMID 12082532 DOI: 10.1038/sj.onc.1205421 |
0.353 |
|
| 2002 |
Ji L, Nishizaki M, Gao B, Burbee D, Kondo M, Kamibayashi C, Xu K, Yen N, Atkinson EN, Fang B, Lerman MI, Roth JA, Minna JD. Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo. Cancer Research. 62: 2715-20. PMID 11980673 |
0.308 |
|
| 2002 |
Moinova HR, Chen WD, Shen L, Smiraglia D, Olechnowicz J, Ravi L, Kasturi L, Myeroff L, Plass C, Parsons R, Minna J, Willson JK, Green SB, Issa JP, Markowitz SD. HLTF gene silencing in human colon cancer. Proceedings of the National Academy of Sciences of the United States of America. 99: 4562-7. PMID 11904375 DOI: 10.1073/Pnas.062459899 |
0.355 |
|
| 2002 |
Fong KM, Minna JD. Molecular biology of lung cancer: clinical implications. Clinics in Chest Medicine. 23: 83-101. PMID 11901922 DOI: 10.1016/s0272-5231(03)00062-5 |
0.322 |
|
| 2002 |
Zochbauer-Muller S, Gazdar AF, Minna JD. Molecular pathogenesis of lung cancer. Annual Review of Physiology. 64: 681-708. PMID 11826285 DOI: 10.1146/ANNUREV.PHYSIOL.64.081501.155828 |
0.417 |
|
| 2001 |
Sekido Y, Fong KM, Minna JD. Molecular genetics of lung cancer. Annual Review of Medicine. 54: 73-87. PMID 12471176 DOI: 10.1146/ANNUREV.MED.54.101601.152202 |
0.463 |
|
| 2001 |
Tomizawa Y, Sekido Y, Kondo M, Gao B, Yokota J, Roche J, Drabkin H, Lerman MI, Gazdar AF, Minna JD. Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B. Proceedings of the National Academy of Sciences of the United States of America. 98: 13954-9. PMID 11717452 DOI: 10.1073/Pnas.231490898 |
0.464 |
|
| 2001 |
Kondo M, Ji L, Kamibayashi C, Tomizawa Y, Randle D, Sekido Y, Yokota J, Kashuba V, Zabarovsky E, Kuzmin I, Lerman M, Roth J, Minna JD. Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells Oncogene. 20: 6258-6262. PMID 11593436 DOI: 10.1038/sj.onc.1204832 |
0.459 |
|
| 2001 |
Shigemitsu K, Sekido Y, Usami N, Mori S, Sato M, Horio Y, Hasegawa Y, Bader SA, Gazdar AF, Minna JD, Hida T, Yoshioka H, Imaizumi M, Ueda Y, Takahashi M, et al. Genetic alteration of the beta-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion. Oncogene. 20: 4249-57. PMID 11464291 DOI: 10.1038/sj.onc.1204557 |
0.391 |
|
| 2001 |
Forgacs E, Zöchbauer-Müller S, Oláh E, Minna JD. Molecular genetic abnormalities in the pathogenesis of human lung cancer. Pathology Oncology Research : Por. 7: 6-13. PMID 11349214 DOI: 10.1007/BF03032598 |
0.432 |
|
| 2001 |
Burbee DG, Forgacs E, Zöchbauer-Müller S, Shivakumar L, Fong K, Gao B, Randle D, Kondo M, Virmani A, Bader S, Sekido Y, Latif F, Milchgrub S, Toyooka S, Gazdar AF, ... ... Minna JD, et al. Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. Journal of the National Cancer Institute. 93: 691-9. PMID 11333291 DOI: 10.1093/JNCI/93.9.691 |
0.361 |
|
| 2001 |
Forgacs E, Wren JD, Kamibayashi C, Kondo M, Xu XL, Markowitz S, Tomlinson GE, Muller CY, Gazdar AF, Garner HR, Minna JD. Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers. Oncogene. 20: 1005-9. PMID 11314036 DOI: 10.1038/Sj.Onc.1204211 |
0.382 |
|
| 2001 |
Agathanggelou A, Honorio S, Macartney DP, Martinez A, Dallol A, Rader J, Fullwood P, Chauhan A, Walker R, Shaw JA, Hosoe S, Lerman MI, Minna JD, Maher ER, Latif F. Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. Oncogene. 20: 1509-18. PMID 11313894 DOI: 10.1038/sj.onc.1204175 |
0.309 |
|
| 2001 |
Ramesh R, Saeki T, Templeton NS, Ji L, Stephens LC, Ito I, Wilson DR, Wu Z, Branch CD, Minna JD, Roth JA. Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 337-50. PMID 11273776 DOI: 10.1006/mthe.2001.0266 |
0.358 |
|
| 2000 |
Dang TP, Gazdar AF, Virmani AK, Sepetavec T, Hande KR, Minna JD, Roberts JR, Carbone DP. Chromosome 19 translocation, overexpression of Notch3, and human lung cancer. Journal of the National Cancer Institute. 92: 1355-7. PMID 10944559 DOI: 10.1093/JNCI/92.16.1355 |
0.346 |
|
| 2000 |
Virmani AK, Rathi A, Zöchbauer-Müller S, Sacchi N, Fukuyama Y, Bryant D, Maitra A, Heda S, Fong KM, Thunnissen F, Minna JD, Gazdar AF. Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas. Journal of the National Cancer Institute. 92: 1303-7. PMID 10944551 DOI: 10.1093/JNCI/92.16.1303 |
0.339 |
|
| 2000 |
Sato M, Sekido Y, Horio Y, Takahashi M, Saito H, Minna JD, Shimokata K, Hasegawa Y. Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancer. Japanese Journal of Cancer Research : Gann. 91: 504-9. PMID 10835495 DOI: 10.1111/j.1349-7006.2000.tb00974.x |
0.468 |
|
| 2000 |
Geradts J, Fong KM, Zimmerman PV, Minna JD. Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features. British Journal of Cancer. 82: 1191-7. PMID 10735505 DOI: 10.1054/bjoc.1999.1062 |
0.344 |
|
| 2000 |
Hamada K, Kohno T, Takahashi M, Yamazaki M, Yamazaki M, Tashiro H, Sugawara C, Ohwada S, Sekido Y, Minna JD, Yokota J. Two regions of homozygous deletion clusters at chromosome band 9p21 in human lung cancer. Genes, Chromosomes & Cancer. 27: 308-18. PMID 10679921 DOI: 10.1002/(SICI)1098-2264(200003)27:3<308::AID-GCC12>3.0.CO;2-W |
0.313 |
|
| 2000 |
Zöchbauer-Müller S, Fong K, Virmani A, Geradts J, Gazdar A, Minna J. Frequent occurance of aberrant promoter methylation of either RARβ, TIMP-3, p16, MGMT, FHIT, DAPK, Ecad, p14 or GSTP1 in resected non-small cell lung cancers Lung Cancer. 29: 207. DOI: 10.1016/S0169-5002(00)80708-4 |
0.361 |
|
| 2000 |
Dang T, Gazdar A, Virmani A, Sepetavec T, Hande K, Minna J, Roberts J, Carbone D. Balanced translocations involving chromosome 19 p in human lung cancer associated with overexpression of Notch3 Lung Cancer. 29: 178. DOI: 10.1016/S0169-5002(00)80597-8 |
0.343 |
|
| 1999 |
Fong KM, Sekido Y, Minna JD. Molecular pathogenesis of lung cancer. The Journal of Thoracic and Cardiovascular Surgery. 118: 1136-52. PMID 10595998 DOI: 10.1016/S0022-5223(99)70121-2 |
0.401 |
|
| 1999 |
Park IW, Wistuba II, Maitra A, Milchgrub S, Virmani AK, Minna JD, Gazdar AF. Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer. Journal of the National Cancer Institute. 91: 1863-8. PMID 10547393 DOI: 10.1093/JNCI/91.21.1863 |
0.37 |
|
| 1999 |
Wang SS, Virmani A, Gazdar AF, Minna JD, Evans GA. Refined mapping of two regions of loss of heterozygosity on chromosome band 11q23 in lung cancer. Genes, Chromosomes & Cancer. 25: 154-9. PMID 10337999 DOI: 10.1002/(Sici)1098-2264(199906)25:2<154::Aid-Gcc11>3.0.Co;2-W |
0.396 |
|
| 1999 |
Gazdar AF, Minna JD. Molecular detection of early lung cancer. Journal of the National Cancer Institute. 91: 299-301. PMID 10050857 DOI: 10.1093/JNCI/91.4.299 |
0.356 |
|
| 1998 |
Sundaresan V, Chung G, Heppell-Parton A, Xiong J, Grundy C, Roberts I, James L, Cahn A, Bench A, Douglas J, Minna J, Sekido Y, Lerman M, Latif F, Bergh J, et al. Homozygous deletions at 3p12 in breast and lung cancer. Oncogene. 17: 1723-9. PMID 9796701 DOI: 10.1038/sj.onc.1202103 |
0.32 |
|
| 1998 |
Forgacs E, Biesterveld EJ, Sekido Y, Fong K, Muneer S, Wistuba II, Milchgrub S, Brezinschek R, Virmani A, Gazdar AF, Minna JD. Mutation analysis of the PTEN/MMAC1 gene in lung cancer. Oncogene. 17: 1557-65. PMID 9794233 DOI: 10.1038/sj.onc.1202070 |
0.452 |
|
| 1998 |
Wang SS, Esplin ED, Li JL, Huang L, Gazdar AF, Minna JD, Evans GA. Alterations of the PPP2R1B Gene in Human Lung and Colon Cancer Science. 282: 284-287. PMID 9765152 DOI: 10.1126/Science.282.5387.284 |
0.362 |
|
| 1998 |
Oh Y, Proctor ML, Fan YH, Su LK, Hong WK, Fong KM, Sekido YS, Gazdar AF, Minna JD, Mao L. TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer. Oncogene. 17: 1141-8. PMID 9764824 DOI: 10.1038/sj.onc.1202029 |
0.457 |
|
| 1998 |
Sekido Y, Fong KM, Minna JD. Progress in understanding the molecular pathogenesis of human lung cancer. Biochimica Et Biophysica Acta. 1378: F21-59. PMID 9739759 DOI: 10.1016/S0304-419X(98)00010-9 |
0.416 |
|
| 1998 |
Sekido Y, Ahmadian M, Wistuba II, Latif F, Bader S, Wei MH, Duh FM, Gazdar AF, Lerman MI, Minna JD. Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene. Oncogene. 16: 3151-7. PMID 9671394 DOI: 10.1038/sj.onc.1201858 |
0.361 |
|
| 1998 |
Virmani AK, Fong KM, Kodagoda D, McIntire D, Hung J, Tonk V, Minna JD, Gazdar AF. Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types. Genes, Chromosomes & Cancer. 21: 308-19. PMID 9559342 DOI: 10.1002/(SICI)1098-2264(199804)21:4<308::AID-GCC4>3.0.CO;2-2 |
0.333 |
|
| 1997 |
Ong ST, Fong KM, Bader SA, Minna JD, Le Beau MM, McKeithan TW, Rassool FV. Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines. Genes, Chromosomes & Cancer. 20: 16-23. PMID 9290949 DOI: 10.1002/(SICI)1098-2264(199709)20:1<16::AID-GCC3>3.0.CO;2-C |
0.367 |
|
| 1997 |
Bansal A, Ramirez RD, Minna JD. Mutation analysis of the coding sequences of MEK-1 and MEK-2 genes in human lung cancer cell lines. Oncogene. 14: 1231-4. PMID 9121773 DOI: 10.1038/sj.onc.1200947 |
0.373 |
|
| 1997 |
Latif F, Duh FM, Bader S, Sekido Y, Li H, Geil L, Zbar B, Minna JD, Lerman MI. The human homolog of the rodent immediate early response genes, PC4 and TIS7, resides in the lung cancer tumor suppressor gene region on chromosome 3p21. Human Genetics. 99: 334-41. PMID 9050919 DOI: 10.1007/s004390050368 |
0.4 |
|
| 1997 |
Fong M, Smith P, Zimmerman P, Minna J. 605 Allele loss at 5Q and 17Q are independent prognostic indicators in resected non small cell lung cancer Lung Cancer. 18: 156. DOI: 10.1016/S0169-5002(97)89985-0 |
0.322 |
|
| 1997 |
Fong K, Biesterveld E, Virmani A, Wistuba I, Sekido Y, Bader S, Ahmadian M, Ong S, Rassool F, Zimmerman P, Giaccone G, Gazdar A, Minna J. 542 Abnormalities of FHIT and the FRA3B fragile site at 3p14.2 in lung cancer and associated preneoplastic lesions Lung Cancer. 18: 139. DOI: 10.1016/S0169-5002(97)89922-9 |
0.307 |
|
| 1997 |
Minna JD. Molecular pathogenesis of lung cancer and the potential translational application of these results to the clinic Lung Cancer. 18: 73-74. DOI: 10.1016/S0169-5002(97)83903-7 |
0.345 |
|
| 1996 |
Shaw GL, Gazdar AF, Phelps R, Steinberg SM, Linnoila RI, Johnson BE, Oie HK, Russell EK, Ghosh BC, Pass HI, Minna JD, Mulshine JL, Ihde DC. Correlation of in vitro drug sensitivity testing results with response to chemotherapy and survival: comparison of non-small cell lung cancer and small cell lung cancer. Journal of Cellular Biochemistry. Supplement. 24: 173-85. PMID 8806100 DOI: 10.1002/JCB.240630513 |
0.325 |
|
| 1996 |
Sekido Y, Bader S, Latif F, Chen JY, Duh FM, Wei MH, Albanesi JP, Lee CC, Lerman MI, Minna JD. Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns. Proceedings of the National Academy of Sciences of the United States of America. 93: 4120-5. PMID 8633026 DOI: 10.1073/pnas.93.9.4120 |
0.351 |
|
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