Year |
Citation |
Score |
2016 |
Hein AL, Seshacharyulu P, Rachagani S, Sheinin YM, Ouellette MM, Ponnusamy MP, Mumby MC, Batra SK, Yan Y. PR55α subunit of protein phosphatase 2A supports the tumorigenic and metastatic potential of pancreatic cancer cells by sustaining hyperactive oncogenic signaling. Cancer Research. PMID 26893480 DOI: 10.1158/0008-5472.Can-15-2119 |
0.346 |
|
2013 |
Wlodarchak N, Guo F, Satyshur KA, Jiang L, Jeffrey PD, Sun T, Stanevich V, Mumby MC, Xing Y. Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Research. 23: 931-46. PMID 23752926 DOI: 10.1038/Cr.2013.77 |
0.404 |
|
2010 |
Jayadeva G, Kurimchak A, Garriga J, Sotillo E, Davis AJ, Haines DS, Mumby M, Graña X. B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation. The Journal of Biological Chemistry. 285: 29863-73. PMID 20663872 DOI: 10.1074/Jbc.M110.162354 |
0.489 |
|
2008 |
Davis AJ, Yan Z, Martinez B, Mumby MC. Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit. The Journal of Biological Chemistry. 283: 16104-14. PMID 18397887 DOI: 10.1074/Jbc.M710313200 |
0.486 |
|
2007 |
Tsao CC, Nica AF, Kurinna SM, Jiffar T, Mumby M, Ruvolo PP. Mitochondrial protein phosphatase 2A regulates cell death induced by simulated ischemia in kidney NRK-52E cells. Cell Cycle (Georgetown, Tex.). 6: 2377-85. PMID 17700073 DOI: 10.4161/Cc.6.19.4737 |
0.338 |
|
2007 |
Mumby M. PP2A: Unveiling a Reluctant Tumor Suppressor Cell. 130: 21-24. PMID 17632053 DOI: 10.1016/J.Cell.2007.06.034 |
0.345 |
|
2007 |
Bielinski VA, Mumby MC. Functional analysis of the PP2A subfamily of protein phosphatases in regulating Drosophila S6 kinase. Experimental Cell Research. 313: 3117-26. PMID 17570358 DOI: 10.1016/J.Yexcr.2007.05.008 |
0.519 |
|
2007 |
Mumby M. The 3D structure of protein phosphatase 2A: new insights into a ubiquitous regulator of cell signaling. Acs Chemical Biology. 2: 99-103. PMID 17313179 DOI: 10.1021/Cb700021Z |
0.391 |
|
2007 |
Fraser I, Liu W, Rebres R, Roach T, Zavzavadjian J, Santat L, Liu J, Wall E, Mumby M. The use of RNA interference to analyze protein phosphatase function in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 365: 261-86. PMID 17200568 DOI: 10.1385/1-59745-267-X:261 |
0.362 |
|
2007 |
Liu W, Silverstein AM, Shu H, Martinez B, Mumby MC. A functional genomics analysis of the B56 isoforms of Drosophila protein phosphatase 2A. Molecular & Cellular Proteomics : McP. 6: 319-32. PMID 17121811 DOI: 10.1074/Mcp.M600272-Mcp200 |
0.444 |
|
2006 |
Emrick MA, Lee T, Starkey PJ, Mumby MC, Resing KA, Ahn NG. The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity. Proceedings of the National Academy of Sciences of the United States of America. 103: 18101-6. PMID 17114285 DOI: 10.1073/pnas.0608849103 |
0.36 |
|
2006 |
Tang Z, Shu H, Qi W, Mahmood NA, Mumby MC, Yu H. PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Developmental Cell. 10: 575-85. PMID 16580887 DOI: 10.1016/J.Devcel.2006.03.010 |
0.55 |
|
2006 |
Esplin ED, Ramos P, Martinez B, Tomlinson GE, Mumby MC, Evans GA. The glycine 90 to aspartate alteration in the Abeta subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function. Genes, Chromosomes & Cancer. 45: 182-90. PMID 16276521 DOI: 10.1002/Gcc.20284 |
0.306 |
|
2004 |
Shu H, Chen S, Bi Q, Mumby M, Brekken DL. Identification of Phosphoproteins and Their Phosphorylation Sites in the WEHI-231 B Lymphoma Cell Line Molecular & Cellular Proteomics. 3: 279-286. PMID 14729942 DOI: 10.1074/Mcp.D300003-Mcp200 |
0.493 |
|
2003 |
Silverstein AM, Mumby MC. Analysis of protein phosphatase function in Drosophila cells using RNA interference. Methods in Enzymology. 366: 361-72. PMID 14674261 DOI: 10.1016/S0076-6879(03)66027-1 |
0.43 |
|
2003 |
Brich J, Shie F, Howell BW, Li R, Tus K, Wakeland EK, Jin L, Mumby M, Churchill G, Herz J, Cooper JA. Genetic Modulation of Tau Phosphorylation in the Mouse The Journal of Neuroscience. 23: 187-192. DOI: 10.1523/Jneurosci.23-01-00187.2003 |
0.332 |
|
2002 |
Ruvolo PP, Clark W, Mumby M, Gao F, May WS. A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function. The Journal of Biological Chemistry. 277: 22847-52. PMID 11929874 DOI: 10.1074/Jbc.M201830200 |
0.405 |
|
2002 |
Silverstein AM, Barrow CA, Davis AJ, Mumby MC. Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits. Proceedings of the National Academy of Sciences of the United States of America. 99: 4221-6. PMID 11904383 DOI: 10.1073/Pnas.072071699 |
0.504 |
|
2001 |
Mumby M. A new role for protein methylation: switching partners at the phosphatase ball. Science Signaling. 2001. PMID 11752649 DOI: 10.1126/Stke.2001.79.Pe1 |
0.373 |
|
2000 |
Price NE, Mumby MC. Effects of regulatory subunits on the kinetics of protein phosphatase 2A. Biochemistry. 39: 11312-8. PMID 10985776 DOI: 10.1021/Bi0008478 |
0.395 |
|
2000 |
Yan Z, Fedorov SA, Mumby MC, Williams RS. PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells. Molecular and Cellular Biology. 20: 1021-9. PMID 10629059 DOI: 10.1128/Mcb.20.3.1021-1029.2000 |
0.432 |
|
1999 |
Price NE, Wadzinski B, Mumby MC. An anchoring factor targets protein phosphatase 2A to brain microtubules. Brain Research. Molecular Brain Research. 73: 68-77. PMID 10581399 DOI: 10.1016/S0169-328X(99)00237-5 |
0.447 |
|
1999 |
Hiesberger T, Trommsdorff M, Howell BW, Goffinet A, Mumby MC, Cooper JA, Herz J. Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Neuron. 24: 481-9. PMID 10571241 DOI: 10.1016/S0896-6273(00)80861-2 |
0.36 |
|
1999 |
Yan Y, Mumby MC. Distinct roles for PP1 and PP2A in phosphorylation of the retinoblastoma protein. PP2a regulates the activities of G(1) cyclin-dependent kinases. The Journal of Biological Chemistry. 274: 31917-24. PMID 10542219 DOI: 10.1074/Jbc.274.45.31917 |
0.499 |
|
1999 |
Sontag E, Nunbhakdi-Craig V, Lee G, Brandt R, Kamibayashi C, Kuret J, White CL, Mumby MC, Bloom GS. Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies. The Journal of Biological Chemistry. 274: 25490-8. PMID 10464280 DOI: 10.1074/Jbc.274.36.25490 |
0.378 |
|
1999 |
Price NE, Mumby MC. Brain protein serine/threonine phosphatases. Current Opinion in Neurobiology. 9: 336-42. PMID 10395578 DOI: 10.1016/S0959-4388(99)80049-X |
0.376 |
|
1998 |
Mateer SC, Fedorov SA, Mumby MC. Identification of structural elements involved in the interaction of simian virus 40 small tumor antigen with protein phosphatase 2A. The Journal of Biological Chemistry. 273: 35339-46. PMID 9857076 DOI: 10.1074/Jbc.273.52.35339 |
0.334 |
|
1998 |
Deng X, Ito T, Carr B, Mumby M, May WS. Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A. Journal of Biological Chemistry. 273: 34157-34163. PMID 9852076 DOI: 10.1074/Jbc.273.51.34157 |
0.458 |
|
1998 |
Griswold-Prenner I, Kamibayashi C, Maruoka EM, Mumby MC, Derynck R. Physical and functional interactions between type I transforming growth factor beta receptors and Balpha, a WD-40 repeat subunit of phosphatase 2A. Molecular and Cellular Biology. 18: 6595-604. PMID 9774674 DOI: 10.1128/Mcb.18.11.6595 |
0.35 |
|
1998 |
Molloy SS, Thomas L, Kamibayashi C, Mumby MC, Thomas G. Regulation of endosome sorting by a specific PP2A isoform. The Journal of Cell Biology. 142: 1399-411. PMID 9744873 DOI: 10.1083/Jcb.142.6.1399 |
0.454 |
|
1998 |
Galadari S, Kishikawa K, Kamibayashi C, Mumby MC, Hannun YA. Purification and characterization of ceramide-activated protein phosphatases. Biochemistry. 37: 11232-8. PMID 9698369 DOI: 10.1021/bi980911 |
0.385 |
|
1997 |
Yan Y, Shay JW, Wright WE, Mumby MC. Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation. The Journal of Biological Chemistry. 272: 15220-6. PMID 9182545 DOI: 10.1074/Jbc.272.24.15220 |
0.389 |
|
1997 |
Zhu T, Matsuzawa S, Mizuno Y, Kamibayashi C, Mumby MC, Andjelkovic N, Hemmings BA, Onoé K, Kikuchi K. The interconversion of protein phosphatase 2A between PP2A1 and PP2A0 during retinoic acid-induced granulocytic differentiation and a modification on the catalytic subunit in S phase of HL-60 cells. Archives of Biochemistry and Biophysics. 339: 210-7. PMID 9056251 DOI: 10.1006/Abbi.1996.9835 |
0.41 |
|
1996 |
Sontag E, Nunbhakdi-Craig V, Lee G, Bloom GS, Mumby MC. Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A. Neuron. 17: 1201-7. PMID 8982166 DOI: 10.1016/S0896-6273(00)80250-0 |
0.432 |
|
1996 |
Tehrani MA, Mumby MC, Kamibayashi C. Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle. The Journal of Biological Chemistry. 271: 5164-70. PMID 8617797 DOI: 10.1074/Jbc.271.9.5164 |
0.385 |
|
1995 |
Mumby M. Regulation by tumour antigens defines a role for PP2A in signal transduction. Seminars in Cancer Biology. 6: 229-237. PMID 8541518 DOI: 10.1006/Scbi.1995.0030 |
0.38 |
|
1995 |
Sontag E, Nunbhakdi-Craig V, Bloom GS, Mumby MC. A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle. The Journal of Cell Biology. 128: 1131-44. PMID 7896877 DOI: 10.1083/Jcb.128.6.1131 |
0.425 |
|
1995 |
Omay SB, Ogasawara H, Toyoda H, Nakai K, Shima H, Nagao M, Mumby MC, Shiku H, Nishikawa M. Translocation of protein phosphatase 1 catalytic subunits during 1,25-dihydroxyvitamin D3-induced monocytic differentiation of HL-60 cells. Cancer Research. 55: 774-80. PMID 7850788 DOI: 10.11501/3100096 |
0.41 |
|
1994 |
Ruediger R, Hentz M, Fait J, Mumby M, Walter G. Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens. Journal of Virology. 68: 123-129. PMID 8254721 DOI: 10.1128/Jvi.68.1.123-129.1994 |
0.4 |
|
1994 |
Sim AT, Ratcliffe E, Mumby MC, Villa-Moruzzi E, Rostas JA. Differential activities of protein phosphatase types 1 and 2A in cytosolic and particulate fractions from rat forebrain. Journal of Neurochemistry. 62: 1552-9. PMID 8133283 DOI: 10.1046/J.1471-4159.1994.62041552.X |
0.379 |
|
1994 |
Nishikawa M, Omay SB, Toyoda H, Tawara I, Shima H, Nagao M, Hemmings BA, Mumby MC, Deguchi K. Expression of the catalytic and regulatory subunits of protein phosphatase type 2A may be differentially modulated during retinoic acid-induced granulocytic differentiation of HL-60 cells. Cancer Research. 54: 4879-84. PMID 8069853 |
0.327 |
|
1994 |
Frost JA, Alberts AS, Sontag E, Guan K, Mumby MC, Feramisco JR. Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity. Molecular and Cellular Biology. 14: 6244-52. PMID 8065356 DOI: 10.1128/Mcb.14.9.6244 |
0.411 |
|
1993 |
Mumby MC, Walter G. Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiological Reviews. 73: 673-99. PMID 8415923 |
0.355 |
|
1993 |
Walter G, Mumby M. Protein serine/threonine phosphatases and cell transformation. Biochimica Et Biophysica Acta. 1155: 207-226. PMID 8395218 DOI: 10.1016/0304-419X(93)90005-W |
0.383 |
|
1993 |
Alberts AS, Deng T, Lin A, Meinkoth JL, Schönthal A, Mumby MC, Karin M, Feramisco JR. Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements. Molecular and Cellular Biology. 13: 2104-12. PMID 8384305 DOI: 10.1128/Mcb.13.4.2104 |
0.405 |
|
1993 |
Alberts AS, Thorburn AM, Shenolikar S, Mumby MC, Feramisco JR. Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. Proceedings of the National Academy of Sciences of the United States of America. 90: 388-92. PMID 8380637 DOI: 10.1073/Pnas.90.2.388 |
0.478 |
|
1993 |
Sontag E, Fedorov S, Kamibayashi C, Robbins D, Cobb M, Mumby M. The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. Cell. 75: 887-97. PMID 8252625 DOI: 10.1016/0092-8674(93)90533-V |
0.474 |
|
1992 |
Nomura M, Stull JT, Kamm KE, Mumby MC. Site-specific dephosphorylation of smooth muscle myosin light chain kinase by protein phosphatases 1 and 2A. Biochemistry. 31: 11915-20. PMID 1332778 DOI: 10.1021/Bi00162A034 |
0.444 |
|
1992 |
Kamibayashi C, Lickteig RL, Estes R, Walter G, Mumby MC. Expression of the A subunit of protein phosphatase 2A and characterization of its interactions with the catalytic and regulatory subunits. The Journal of Biological Chemistry. 267: 21864-72. PMID 1328247 |
0.314 |
|
1992 |
Kubota Y, Nomura M, Kamm KE, Mumby MC, Stull JT. GTP gamma S-dependent regulation of smooth muscle contractile elements. The American Journal of Physiology. 262: C405-10. PMID 1311501 DOI: 10.1152/Ajpcell.1992.262.2.C405 |
0.363 |
|
1991 |
Lee TH, Solomon MJ, Mumby MC, Kirschner MW. INH, a negative regulator of MPF, is a form of protein phosphatase 2A. Cell. 64: 415-23. PMID 1846321 DOI: 10.1016/0092-8674(91)90649-J |
0.509 |
|
1991 |
Yang SI, Lickteig RL, Estes R, Rundell K, Walter G, Mumby MC. Control of protein phosphatase 2A by simian virus 40 small-t antigen. Molecular and Cellular Biology. 11: 1988-95. PMID 1706474 DOI: 10.1128/Mcb.11.4.1988 |
0.429 |
|
1991 |
Mumby MC, Walter G. Protein phosphatases and DNA tumor viruses: transformation through the back door? Cell Regulation. 2: 589-98. PMID 1663787 |
0.328 |
|
1991 |
Ruediger R, Hood JEVW, Mumby M, Walter G. Constant expression and activity of protein phosphatase 2A in synchronized cells. Molecular and Cellular Biology. 11: 4282-4285. PMID 1649390 DOI: 10.1128/Mcb.11.8.4282 |
0.464 |
|
1991 |
Kamibayashi C, Estes R, Slaughter C, Mumby MC. Subunit interactions control protein phosphatase 2A. Effects of limited proteolysis, N-ethylmaleimide, and heparin on the interaction of the B subunit. The Journal of Biological Chemistry. 266: 13251-60. PMID 1649186 |
0.354 |
|
1990 |
Fernandez A, Brautigan DL, Mumby M, Lamb NJC. Protein phosphatase type-1, not type-2A, modulates actin microfilament integrity and myosin light chain phosphorylation in living nonmuscle cells Journal of Cell Biology. 111: 103-112. PMID 2164027 DOI: 10.1083/Jcb.111.1.103 |
0.309 |
|
1990 |
Walter G, Ruediger R, Slaughter CA, Mumby M. Association of protein phosphatase 2A with polyoma virus medium tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 87: 2521-2525. PMID 2157202 DOI: 10.1073/Pnas.87.7.2521 |
0.402 |
|
1989 |
Scott CW, Mumby MC. Autophosphorylation of rat liver type II cAMP-dependent protein kinase. Molecular Endocrinology (Baltimore, Md.). 3: 1815-22. PMID 2558304 DOI: 10.1210/Mend-3-11-1815 |
0.404 |
|
1988 |
Mumby MC, Scott CW. cAMP-dependent protein kinase regulatory subunit phosphorylation in intact cells. Methods in Enzymology. 159: 139-46. PMID 3412178 DOI: 10.1016/0076-6879(88)59014-6 |
0.467 |
|
1987 |
Green DD, Yang SI, Mumby MC. Molecular cloning and sequence analysis of the catalytic subunit of bovine type 2A protein phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 84: 4880-4. PMID 3037526 DOI: 10.1073/Pnas.84.14.4880 |
0.348 |
|
1987 |
Johnson GL, Brautigan DL, Shriner C, Jaspers S, Arino J, Mole JE, Miller TB, Mumby MC. Sequence homologies between type 1 and type 2A protein phosphatases. Molecular Endocrinology (Baltimore, Md.). 1: 745-8. PMID 2856400 DOI: 10.1210/Mend-1-10-745 |
0.334 |
|
1986 |
Lawrence JC, Hiken JF, Inkster M, Scott CW, Mumby MC. Insulin stimulates the generation of an adipocyte phosphoprotein that is isolated with a monoclonal antibody against the regulatory subunit of bovine heart cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 83: 3649-53. PMID 2424009 DOI: 10.1073/Pnas.83.11.3649 |
0.388 |
|
1985 |
Scott CW, Mumby MC. Phosphorylation of type II regulatory subunit of cAMP-dependent protein kinase in intact smooth muscle. The Journal of Biological Chemistry. 260: 2274-80. PMID 2982813 |
0.336 |
|
1984 |
Scott CW, Mumby MC. Regulation of the phosphorylation state of the type II regulatory subunit of cAMP dependent protein kinase in vivo Federation Proceedings. 43: no. 3083. |
0.355 |
|
1982 |
Doherty PJ, Tsao J, Schimmer BP, Mumby MC, Beavo JA. Alteration of the regulatory subunit of type 1 cAMP-dependent protein kinase in mutant Y1 adrenal cells resistant to 8-bromoadenosine 3':5'-monophosphate. The Journal of Biological Chemistry. 257: 5877-83. PMID 6279618 |
0.344 |
|
1980 |
Mumby M, Traugh JA. Multiple forms of phosphoprotein phosphatase from rabbit reticulocytes Bba - Enzymology. 611: 342-350. PMID 6243990 DOI: 10.1016/0005-2744(80)90070-4 |
0.56 |
|
1979 |
Mumby M, Traugh JA. Dephosphorylation of translational initiation factors and 40S ribosomal subunits by phosphoprotein phosphatases from rabbit reticulocytes Biochemistry. 18: 4548-4556. PMID 227442 DOI: 10.1021/Bi00588A015 |
0.579 |
|
1979 |
Mumby M, Traugh JA. [47] Dephosphorylation of translational components of phosphoprotein phosphatases from reticulocytes Methods in Enzymology. 60: 522-534. DOI: 10.1016/S0076-6879(79)60049-6 |
0.547 |
|
1975 |
Lightfoot HN, Mumby M, Traugh JA. Dephosphorylation of 40S ribosomal subunits by phosphoprotein phosphatase activity from rabbit reticulocytes Biochemical and Biophysical Research Communications. 66: 1141-1146. PMID 172072 DOI: 10.1016/0006-291X(75)90477-5 |
0.634 |
|
1973 |
Trauch JA, Mumby M, Traut RR. Phosphorylation of ribosomal proteins by substrate-specific protein kinases from rabbit reticulocytes. Proceedings of the National Academy of Sciences of the United States of America. 70: 373-6. PMID 4346887 DOI: 10.1073/Pnas.70.2.373 |
0.498 |
|
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