Year |
Citation |
Score |
2019 |
Maniero C, Scudieri P, Haris Shaikh L, Zhao W, Gurnell M, Galietta LJV, Brown MJ. ANO4 (Anoctamin 4) Is a Novel Marker of Zona Glomerulosa That Regulates Stimulated Aldosterone Secretion. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 31564164 DOI: 10.1161/Hypertensionaha.119.13287 |
0.728 |
|
2018 |
Williams B, MacDonald TM, Morant SV, Webb DJ, Sever P, McInnes GT, Ford I, Cruickshank JK, Caulfield MJ, Padmanabhan S, Mackenzie IS, Salsbury J, Brown MJ. Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies. The Lancet. Diabetes & Endocrinology. PMID 29655877 DOI: 10.1016/S2213-8587(18)30071-8 |
0.304 |
|
2017 |
Brown MJ. Rapid Diagnosis of Primary Aldosteronism: Oxymoron or One Small Step? Hypertension (Dallas, Tex. : 1979). PMID 28652464 DOI: 10.1161/Hypertensionaha.117.09199 |
0.31 |
|
2017 |
Maniero C, Garg S, Zhao W, Johnson TI, Zhou J, Gurnell M, Brown MJ. NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone. Hypertension (Dallas, Tex. : 1979). PMID 28584012 DOI: 10.1161/Hypertensionaha.117.09231 |
0.326 |
|
2017 |
Teo AE, Garg S, Johnson TI, Zhao W, Zhou J, Gomez-Sanchez CE, Gurnell M, Brown MJ. Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin). Hypertension (Dallas, Tex. : 1979). PMID 28416583 DOI: 10.1161/Hypertensionaha.117.09156 |
0.342 |
|
2016 |
Bogman K, Schwab D, Delporte ML, Palermo G, Amrein K, Mohr S, De Vera Mudry MC, Brown MJ, Ferber P. Preclinical and Early Clinical Profile of a Highly Selective and Potent Oral Inhibitor of Aldosterone Synthase (CYP11B2). Hypertension (Dallas, Tex. : 1979). PMID 27872236 DOI: 10.1161/Hypertensionaha.116.07716 |
0.317 |
|
2016 |
Zhou J, Lam B, Neogi S, Yeo G, Azizan E, Brown M. ISH ADA-04 TRANSCRIPTOME PATHWAY ANALYSIS OF AUTONOMOUS AND PHYSIOLOGICAL ALDOSTERONE-PRODUCING HUMAN TISSUE. Journal of Hypertension. 34: e40. PMID 27643206 DOI: 10.1097/01.Hjh.0000499958.18632.E9 |
0.321 |
|
2016 |
Zhou J, Lam BY, Neogi SG, Yeo GS, Teo AE, Maniero C, Azizan EA, Brown MJ. [OP.3A.01] THE COMPARISON OF THE TRANSCRIPTOME PROFILE OF THE AUTONOMOUS AND THE PHYSIOLOGICAL ALDOSTERONE-PRODUCING TISSUE, THE ALDOSTERONE-PRODUCING ADENOMA AND THE ZONA GLOMERULOSA. Journal of Hypertension. 34: e26. PMID 27508643 DOI: 10.1097/01.Hjh.0000491398.48468.Bf |
0.315 |
|
2016 |
Petruzzelli M, Taylor KP, Koo B, Brown MJ. Telling Tails: Very High Plasma Renin Levels Prompt the Diagnosis of Renal Artery Stenosis, Despite Initial Negative Imaging. Hypertension. PMID 27217414 DOI: 10.1161/Hypertensionaha.116.07433 |
0.327 |
|
2016 |
Xie CB, Haris Shaikh L, Garg S, Tanriver G, Teo AE, Zhou J, Maniero C, Zhao W, Kang S, Silverman RB, Azizan EA, Brown MJ. Regulation of aldosterone secretion by Cav1.3. Scientific Reports. 6: 24697. PMID 27098837 DOI: 10.1038/Srep24697 |
0.305 |
|
2016 |
Azizan EA, Brown MJ. Novel genetic determinants of adrenal aldosterone regulation. Current Opinion in Endocrinology, Diabetes, and Obesity. PMID 26992195 DOI: 10.1097/Med.0000000000000255 |
0.334 |
|
2016 |
Teo AED, Garg S, Haris Shaikh L, Zhou J, Karet Frankl FE, Gurnell M, Happerfield L, Marker A, Bienz M, Azizan EAB, Brown MJ. Effect of somatic CTNNB1 mutations on adrenocortical cell de-differentiation in adenoma presenting in early pregnancy or menopause Annales D'Endocrinologie. 77: 161-162. DOI: 10.1016/J.Ando.2016.04.022 |
0.331 |
|
2015 |
Brown MJ, Williams B, Morant SV, Webb DJ, Caulfield MJ, Cruickshank JK, Ford I, McInnes G, Sever P, Salsbury J, Mackenzie IS, Padmanabhan S, MacDonald TM. Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial. The Lancet. Diabetes & Endocrinology. PMID 26489809 DOI: 10.1016/S2213-8587(15)00377-0 |
0.316 |
|
2015 |
Williams B, MacDonald TM, Morant S, Webb DJ, Sever P, McInnes G, Ford I, Cruickshank JK, Caulfield MJ, Salsbury J, Mackenzie I, Padmanabhan S, Brown MJ. Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial. Lancet (London, England). PMID 26414968 DOI: 10.1016/S0140-6736(15)00257-3 |
0.322 |
|
2015 |
Teo AE, Garg S, Haris Shaikh L, Zhou J, Karet Frankl FE, Gurnell M, Happerfield L, Marker A, Bienz M, Azizan EA, Brown MJ. Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations. The New England Journal of Medicine. PMID 26397949 DOI: 10.1056/Nejmoa1504869 |
0.725 |
|
2015 |
Maniero C, Zhou J, Shaikh LH, Azizan EA, McFarlane I, Neogi S, Scudieri P, Galietta LJ, Brown MJ. Role of ANO4 in regulation of aldosterone secretion in the zona glomerulosa of the human adrenal gland. Lancet (London, England). 385: S62. PMID 26312884 DOI: 10.1016/S0140-6736(15)60377-4 |
0.334 |
|
2015 |
Williams B, MacDonald TM, Caulfield M, Cruickshank JK, McInnes G, Sever P, Webb DJ, Salsbury J, Morant S, Ford I, Brown MJ. Prevention And Treatment of Hypertension With Algorithm-based therapy (PATHWAY) number 2: protocol for a randomised crossover trial to determine optimal treatment for drug-resistant hypertension. Bmj Open. 5: e008951. PMID 26253568 DOI: 10.1136/Bmjopen-2015-008951 |
0.315 |
|
2015 |
MacDonald TM, Williams B, Caulfield M, Cruickshank JK, McInnes G, Sever P, Webb DJ, Mackenzie IS, Salsbury J, Morant S, Ford I, Brown MJ. Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1): a randomised double-blind controlled trial. Bmj Open. 5: e007645. PMID 26253566 DOI: 10.1136/Bmjopen-2015-007645 |
0.3 |
|
2015 |
Shaikh LH, Zhou J, Teo AE, Garg S, Neogi SG, Figg N, Yeo GS, Yu H, Maguire JJ, Zhao W, Bennett MR, Azizan EA, Davenport AP, McKenzie G, Brown MJ. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. The Journal of Clinical Endocrinology and Metabolism. 100: E836-44. PMID 25915569 DOI: 10.1210/Jc.2015-1734 |
0.446 |
|
2015 |
Zhou J, Shaikh LH, Neogi SG, McFarlane I, Zhao W, Figg N, Brighton CA, Maniero C, Teo AE, Azizan EA, Brown MJ. DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretion. Hypertension. 65: 1103-10. PMID 25776071 DOI: 10.1161/Hyp.0000000000000025 |
0.303 |
|
2014 |
Brown MJ. Resistant hypertension: resistance to treatment or resistance to taking treatment? Heart (British Cardiac Society). 100: 821-2. PMID 24694796 DOI: 10.1136/Heartjnl-2014-305540 |
0.301 |
|
2014 |
Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, ... ... Brown M, et al. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics. 94: 349-60. PMID 24560520 DOI: 10.1016/J.Ajhg.2013.12.016 |
0.319 |
|
2014 |
Brown MJ. Ins and outs of aldosterone-producing adenomas of the adrenal: from channelopathy to common curable cause of hypertension. Hypertension. 63: 24-6. PMID 24082060 DOI: 10.1161/Hypertensionaha.113.01833 |
0.344 |
|
2013 |
Azizan EA, Poulsen H, Tuluc P, Zhou J, Clausen MV, Lieb A, Maniero C, Garg S, Bochukova EG, Zhao W, Shaikh LH, Brighton CA, Teo AE, Davenport AP, Dekkers T, ... ... Brown MJ, et al. Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nature Genetics. 45: 1055-60. PMID 23913004 DOI: 10.1038/Ng.2716 |
0.45 |
|
2013 |
Bramham K, Nelson-Piercy C, Brown MJ, Chappell LC. Postpartum management of hypertension. Bmj (Clinical Research Ed.). 346: f894. PMID 23440270 DOI: 10.1136/Bmj.F894 |
0.315 |
|
2013 |
Alvarez-Madrazo S, Mackenzie SM, Davies E, Fraser R, Lee WK, Brown M, Caulfield MJ, Dominiczak AF, Farrall M, Lathrop M, Hedner T, Melander O, Munroe PB, Samani N, Stewart PM, et al. Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension. Hypertension. 61: 232-9. PMID 23150505 DOI: 10.1161/Hypertensionaha.112.200741 |
0.315 |
|
2011 |
Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, ... ... Brown MJ, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 478: 103-9. PMID 21909115 DOI: 10.1038/Nature10405 |
0.316 |
|
2011 |
Brown MJ. The choice of diuretic in hypertension: saving the baby from the bathwater. Heart (British Cardiac Society). 97: 1547-51. PMID 21900583 DOI: 10.1136/Heartjnl-2011-300710 |
0.311 |
|
2011 |
Brown MJ. Personalised medicine for hypertension. Bmj (Clinical Research Ed.). 343: d4697. PMID 21798973 DOI: 10.1136/Bmj.D4697 |
0.364 |
|
2011 |
Burton TJ, Azizan EA, Brown MJ. Investigating the function of an aldosterone response pathway in primary human adrenocortical cells obtained from Conn's and phaeochromocytoma patients. European Journal of Pharmacology. 657: 184-9. PMID 21300056 DOI: 10.1016/J.Ejphar.2011.01.051 |
0.309 |
|
2011 |
Brown MJ, McInnes GT, Papst CC, Zhang J, MacDonald TM. Aliskiren and the calcium channel blocker amlodipine combination as an initial treatment strategy for hypertension control (ACCELERATE): a randomised, parallel-group trial. Lancet. 377: 312-20. PMID 21236483 DOI: 10.1016/S0140-6736(10)62003-X |
0.314 |
|
2009 |
Mackenzie IS, McEniery CM, Dhakam Z, Brown MJ, Cockcroft JR, Wilkinson IB. Comparison of the effects of antihypertensive agents on central blood pressure and arterial stiffness in isolated systolic hypertension. Hypertension. 54: 409-13. PMID 19487582 DOI: 10.1161/Hypertensionaha.109.133801 |
0.315 |
|
2009 |
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, ... ... Brown M, et al. Genome-wide association study identifies eight loci associated with blood pressure. Nature Genetics. 41: 666-76. PMID 19430483 DOI: 10.1038/Ng.361 |
0.309 |
|
2009 |
Burton TJ, Cope G, Wang J, Sim JC, Azizan EA, O'Shaughnessy KM, Brown MJ. Expression of the epithelial Na(+) channel and other components of an aldosterone response pathway in human adrenocortical cells. European Journal of Pharmacology. 613: 176-81. PMID 19371736 DOI: 10.1016/J.Ejphar.2009.04.005 |
0.31 |
|
2009 |
Newhouse S, Farrall M, Wallace C, Hoti M, Burke B, Howard P, Onipinla A, Lee K, Shaw-Hawkins S, Dobson R, Brown M, Samani NJ, Dominiczak AF, Connell JM, Lathrop GM, et al. Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion. Plos One. 4: e5003. PMID 19347040 DOI: 10.1371/Journal.Pone.0005003 |
0.327 |
|
2009 |
Org E, Eyheramendy S, Juhanson P, Gieger C, Lichtner P, Klopp N, Veldre G, Döring A, Viigimaa M, Sõber S, Tomberg K, Eckstein G, Kelgo P, Rebane T, ... ... Brown M, et al. Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations. Human Molecular Genetics. 18: 2288-96. PMID 19304780 DOI: 10.1093/Hmg/Ddp135 |
0.322 |
|
2009 |
Mackenzie IS, Brown MJ. Molecular and clinical investigations in patients with low-renin hypertension. Clinical and Experimental Nephrology. 13: 1-8. PMID 18704622 DOI: 10.1007/S10157-008-0071-4 |
0.325 |
|
2008 |
Myint KS, Watts M, Appleton DS, Lomas DJ, Jamieson N, Taylor KP, Coghill S, Brown MJ. Primary hyperaldosteronism due to adrenal microadenoma: a curable cause of refractory hypertension. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 9: 103-6. PMID 18584586 DOI: 10.3317/Jraas.2008.015 |
0.341 |
|
2008 |
Dhakam Z, Yasmin, McEniery CM, Burton T, Brown MJ, Wilkinson IB. A comparison of atenolol and nebivolol in isolated systolic hypertension. Journal of Hypertension. 26: 351-6. PMID 18192850 DOI: 10.1097/Hjh.0B013E3282F283C9 |
0.31 |
|
2008 |
Brown MJ, Toal CB. Formulation of long-acting nifedipine tablets influences the heart rate and sympathetic nervous system response in hypertensive patients. British Journal of Clinical Pharmacology. 65: 646-52. PMID 18093252 DOI: 10.1111/J.1365-2125.2007.03082.X |
0.333 |
|
2008 |
Brown MJ, Hood SJ, Ashby MJ, Taylor KP. Response to letter regarding article, "the spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio" Circulation. 117: e152. DOI: 10.1161/Circulationaha.107.744250 |
0.307 |
|
2007 |
Mir FA, Brown MJ, Appleton DS. Lessons in the diagnosis and management of Conn's syndrome. Clinical Medicine (London, England). 7: 530-1. PMID 17990731 DOI: 10.7861/Clinmedicine.7-5-530 |
0.307 |
|
2007 |
Hood SJ, Taylor KP, Ashby MJ, Brown MJ. The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. Circulation. 116: 268-75. PMID 17606839 DOI: 10.1161/Circulationaha.107.690396 |
0.327 |
|
2007 |
Brown MJ. Renin: friend or foe? Heart (British Cardiac Society). 93: 1026-33. PMID 17488768 DOI: 10.1136/Hrt.2006.107706 |
0.339 |
|
2007 |
Burton TJ, O'Shaughnessy KM, Brown MJ. The epithelial Na+ channel as a determinant of blood pressure Current Hypertension Reviews. 3: 45-49. DOI: 10.2174/157340207779815491 |
0.352 |
|
2006 |
Brown MJ. Hypertension and ethnic group. Bmj (Clinical Research Ed.). 332: 833-6. PMID 16601044 DOI: 10.1136/Bmj.332.7545.833 |
0.308 |
|
2006 |
Padmanabhan S, Wallace C, Munroe PB, Dobson R, Brown M, Samani N, Clayton D, Farrall M, Webster J, Lathrop M, Caulfield M, Dominiczak AF, Connell JM. Chromosome 2p shows significant linkage to antihypertensive response in the British Genetics of Hypertension Study. Hypertension. 47: 603-8. PMID 16391175 DOI: 10.1161/01.Hyp.0000197947.62601.9D |
0.338 |
|
2005 |
Mackenzie IS, Maki-Petaja KM, McEniery CM, Bao YP, Wallace SM, Cheriyan J, Monteith S, Brown MJ, Wilkinson IB. Aldehyde dehydrogenase 2 plays a role in the bioactivation of nitroglycerin in humans. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1891-5. PMID 16051882 DOI: 10.1161/01.Atv.0000179599.71086.89 |
0.309 |
|
2005 |
Newhouse SJ, Wallace C, Dobson R, Mein C, Pembroke J, Farrall M, Clayton D, Brown M, Samani N, Dominiczak A, Connell JM, Webster J, Lathrop GM, Caulfield M, Munroe PB. Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. Human Molecular Genetics. 14: 1805-14. PMID 15888480 DOI: 10.1093/Hmg/Ddi187 |
0.318 |
|
2005 |
Hood S, Cannon J, Foo R, Brown M. Prevalence of primary hyperaldosteronism assessed by aldosterone/renin ratio and spironolactone testing Clinical Medicine. 5: 55-60. PMID 15745200 DOI: 10.7861/Clinmedicine.5-1-55 |
0.346 |
|
2004 |
Brown MJ, Coltart J, Gunewardena K, Ritter JM, Auton TR, Glover JF. Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects. Clinical Science (London, England : 1979). 107: 167-73. PMID 15040783 DOI: 10.1042/Cs20030381 |
0.315 |
|
2004 |
Williams B, Poulter NR, Brown MJ, Davis M, McInnes GT, Potter JF, Sever PS, Thom SM. British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary. Bmj (Clinical Research Ed.). 328: 634-40. PMID 15016698 DOI: 10.1136/Bmj.328.7440.634 |
0.307 |
|
2003 |
Brown MJ, Cruickshank JK, Dominiczak AF, MacGregor GA, Poulter NR, Russell GI, Thom S, Williams B. Better blood pressure control: how to combine drugs Journal of Human Hypertension. 17: 81-86. PMID 12574784 DOI: 10.1038/Sj.Jhh.1001511 |
0.308 |
|
2001 |
Foo R, O'Shaughnessy KM, Brown MJ. Hyperaldosteronism: recent concepts, diagnosis, and management. Postgraduate Medical Journal. 77: 639-44. PMID 11571370 DOI: 10.1136/Pmj.77.912.639 |
0.352 |
|
2001 |
Brown MJ. Matching the right drug to the right patient in essential hypertension Heart. 86: 113-120. PMID 11410577 DOI: 10.1136/Heart.86.1.113 |
0.303 |
|
2000 |
Brown MJ, Sharma P, Stevens PA. Association between diastolic blood pressure and variants of the endothelin-1 and endothelin-2 genes Journal of Cardiovascular Pharmacology. 35. PMID 10976780 DOI: 10.1097/00005344-200000002-00010 |
0.308 |
|
2000 |
Brown MJ, Palmer CR, Castaigne A, de Leeuw PW, Mancia G, Rosenthal T, Ruilope LM. Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). Lancet. 356: 366-72. PMID 10972368 DOI: 10.1016/S0140-6736(00)02527-7 |
0.324 |
|
2000 |
Brown MJ, Castaigne A, de Leeuw PW, Mancia G, Palmer CR, Rosenthal T, Ruilope LM. Influence of diabetes and type of hypertension on response to antihypertensive treatment. Hypertension. 35: 1038-42. PMID 10818061 DOI: 10.1161/01.Hyp.35.5.1038 |
0.303 |
|
2000 |
Brown MJ, Haydock S. Pathoaetiology, epidemiology and diagnosis of hypertension. Drugs. 59: 1-12. PMID 10678592 DOI: 10.2165/00003495-200059002-00001 |
0.32 |
|
1999 |
Sharma P, Hingorani A, Jia H, Hopper R, Brown MJ. Quantitative association between a newly identified molecular variant in the endothelin-2 gene and human essential hypertension. Journal of Hypertension. 17: 1281-1287. PMID 10489105 DOI: 10.1097/00004872-199917090-00007 |
0.33 |
|
1999 |
Jia H, Hingorani AD, Sharma P, Hopper R, Dickerson C, Trutwein D, Lloyd DD, Brown MJ. Association of the Gsα Gene With Essential Hypertension and Response to β-Blockade Hypertension. 34: 8-14. PMID 10406816 DOI: 10.1161/01.Hyp.34.1.8 |
0.337 |
|
1999 |
Dickerson JE, Hingorani AD, Ashby MJ, Palmer CR, Brown MJ. Optimisation of antihypertensive treatment by crossover rotation of four major classes. Lancet. 353: 2008-13. PMID 10376615 DOI: 10.1016/S0140-6736(98)07614-4 |
0.306 |
|
1997 |
Brown MJ. Science, medicine, and the future : Hypertension Bmj. 314: 1258-1258. PMID 9154032 DOI: 10.1136/Bmj.314.7089.1258 |
0.326 |
|
1997 |
Medina R, Cardona-Sanclemente LE, Born GV, Brown MJ. Effect of captopril and losartan on blood pressure and accumulation of LDL and fibrinogen by aortic wall and other tissues in normotensive and hypertensive rats. Journal of Cardiovascular Pharmacology. 29: 125-9. PMID 9007681 DOI: 10.1097/00005344-199701000-00019 |
0.325 |
|
1996 |
Hingorani AD, Sharma P, Jia H, Hopper R, Brown MJ. Blood pressure and the M235T polymorphism of the angiotensinogen gene. Hypertension. 28: 907-911. PMID 8901843 DOI: 10.1161/01.Hyp.28.5.907 |
0.318 |
|
1996 |
Brown MJ. The causes of essential hypertension British Journal of Clinical Pharmacology. 42: 21-27. PMID 8807140 DOI: 10.1046/J.1365-2125.1996.03785.X |
0.338 |
|
1995 |
Stevens PA, Brown MJ. Genetic variability of the ET-1 and the ETA receptor genes in essential hypertension. Journal of Cardiovascular Pharmacology. 25. DOI: 10.1097/00005344-199506263-00004 |
0.3 |
|
1995 |
Hingorani AD, Jia H, Stevens PA, Hopper R, Dickerson JEC, Brown MJ. Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition. Journal of Hypertension. 13: 1602-1609. DOI: 10.1097/00004872-199512000-00027 |
0.301 |
|
1990 |
Davenport AP, Ashby MJ, Easton P, Ella S, Bedford J, Dickerson C, Nunez DJ, Capper SJ, Brown MJ. A sensitive radioimmunoassay measuring endothelin-like immunoreactivity in human plasma: Comparison of levels in patients with essential hypertension and normotensive control subjects Clinical Science. 78: 261-264. PMID 2156645 DOI: 10.1042/Cs0780261 |
0.331 |
|
1988 |
Morice A, Pepke-Zaba J, Loysen E, Lapworth R, Ashby M, Higenbottam T, Brown M. Low dose infusion of atrial natriuretic peptide causes salt and water excretion in normal man. Clinical Science. 74: 359-363. PMID 2965631 DOI: 10.1042/Cs0740359 |
0.326 |
|
1986 |
Barnes PJ, Brown MJ, Dollery CT, Fuller RW, Heavey DJ, Ind PW. Histamine is released from skin by substance P but does not act as the final vasodilator in the axon reflex. British Journal of Pharmacology. 88: 741-5. PMID 2427144 DOI: 10.1111/J.1476-5381.1986.Tb16246.X |
0.457 |
|
1985 |
Ind PW, Barnes PJ, Brown MJ, Dollery CT. Plasma histamine concentration during propranolol induced bronchoconstriction. Thorax. 40: 903-9. PMID 4095670 DOI: 10.1136/Thx.40.12.903 |
0.486 |
|
1985 |
Struthers AD, Brown MJ, Adams EF, Dollery CT. The plasma noradrenaline and growth hormone response to alpha-methyldopa and clonidine in hypertensive subjects. British Journal of Clinical Pharmacology. 19: 311-7. PMID 3986086 DOI: 10.1111/J.1365-2125.1985.Tb02649.X |
0.483 |
|
1985 |
Brown MJ, Struthers AD, Silvio LD, Yeo T, Ghatei M, Burrin JM. Metabolic and haemodynamic effects of alpha 2-adrenoceptor stimulation and antagonism in man. Clinical Science. 68. PMID 2857610 DOI: 10.1042/Cs068S137 |
0.313 |
|
1985 |
Brown MJ, Struthers AD, Silvio Ld. Peripheral alpha 2 adrenoceptor stimulation contributes to the sympatholytic effect of guanfacine in humans. Journal of Cardiovascular Pharmacology. 7. PMID 2414580 DOI: 10.1097/00005344-198500076-00027 |
0.327 |
|
1985 |
Brown MJ, Causon RC, Barnes VF, Brennan P, Barnes G, Greenberg G. Urinary Catecholamines in Essential Hypertension: Results of 24-hour Urine Catecholamine Analyses from Patients in the Medical Research Council Trial for Mild Hypertension and from Matched Controls Qjm: An International Journal of Medicine. 57: 637-651. DOI: 10.1093/Oxfordjournals.Qjmed.A067908 |
0.332 |
|
1984 |
Conway EL, Brown MJ, Dollery CT. No evidence for involvement of endogenous opioid peptides in effects of clonidine on blood pressure, heart rate and plasma norepinephrine in anesthetized rats. The Journal of Pharmacology and Experimental Therapeutics. 229: 803-8. PMID 6726658 |
0.42 |
|
1984 |
Murphy MB, Brown MJ, Dollery CT. Evidence for a peripheral component in the sympatholytic actions of clonidine and guanfacine in man. European Journal of Clinical Pharmacology. 27: 23-7. PMID 6386488 DOI: 10.1007/BF00553149 |
0.406 |
|
1984 |
Scriven AJ, Brown MJ, Murphy MB, Dollery CT. Changes in blood pressure and plasma catecholamines caused by tyramine and cold exposure. Journal of Cardiovascular Pharmacology. 6: 954-60. PMID 6209506 DOI: 10.1097/00005344-198409000-00033 |
0.515 |
|
1984 |
Conway EL, Brown MJ, Dollery CT. Studies on the pharmacology of central opioid-induced increases in plasma catecholamines in conscious rats. Neuropharmacology. 23: 1291-6. PMID 6152020 |
0.39 |
|
1984 |
Brown MJ, Harland D, Murphy MB, Struthers AD. Effect of Centrally Acting α-Adrenergic Agonists on Sympathetic Nervous System Function in Humans Hypertension. 6: 57-62. PMID 6150000 DOI: 10.1161/01.Hyp.6.5_Pt_2.Ii57 |
0.308 |
|
1984 |
Brown MJ, Dollery CT. Adrenaline and hypertension. Clinical and Experimental Hypertension. Part a, Theory and Practice. 6: 539-49. PMID 6141856 DOI: 10.3109/10641968409062582 |
0.397 |
|
1984 |
Murphy MB, Brown MJ, Dollery CT. Location of vascular alpha 2-adrenoceptors in man. British Journal of Clinical Pharmacology. 18: 955-8. PMID 6099135 DOI: 10.1111/J.1365-2125.1984.Tb02570.X |
0.463 |
|
1984 |
Murphy MB, Brown MJ, Scriven AJ, Heavey DJ, Dollery CT. Nifedipine and alpha adrenoceptor antagonism. Clinical Pharmacology and Therapeutics. 36: 745-9. PMID 6094077 DOI: 10.1038/Clpt.1984.252 |
0.472 |
|
1984 |
Heavey DJ, Ind PW, Miyatake A, Brown MJ, Macdermot J, Dollery CT. Histamine released locally after intradermal antigen challenge in man. British Journal of Clinical Pharmacology. 18: 915-9. PMID 6085003 DOI: 10.1111/j.1365-2125.1984.tb02564.x |
0.399 |
|
1984 |
Brown MJ, Causon RC, Barnes V, Barnes G, Greenberg G, Brennan P, Miall WE. 4 Adrenaline and Hypertension in Man Journal of Hypertension. 2: 554-555. DOI: 10.1097/00004872-198410000-00020 |
0.304 |
|
1983 |
Scriven AJ, Dollery CT, Murphy MB, Macquin I, Brown MJ. Blood pressure and plasma norepinephrine concentrations after endogenous norepinephrine release by tyramine. Clinical Pharmacology and Therapeutics. 33: 710-6. PMID 6851403 DOI: 10.1038/Clpt.1983.97 |
0.492 |
|
1983 |
Murphy MB, Brown MJ, Causon RC, Dollery CT. The effects of pentolinium on sympathetic activity in hypertensives and normotensive controls. International Journal of Clinical Pharmacology Research. 3: 227-32. PMID 6678820 |
0.459 |
|
1983 |
Dollery CT, Brown MJ, Davies DS, Lewis PJ, Strolin-Benedetti M. Oral absorption and concentration-effect relationship of tyramine with and without cimoxatone, a type-A specific inhibitor of monoamine oxidase. Clinical Pharmacology and Therapeutics. 34: 651-62. PMID 6627826 DOI: 10.1038/Clpt.1983.228 |
0.472 |
|
1983 |
Conway EL, Brown MJ, Dollery CT. Plasma catecholamine and cardiovascular responses to morphine and D-ala2-d-leu5-enkephalin in conscious rats. Archives Internationales De Pharmacodynamie Et De ThéRapie. 265: 244-58. PMID 6360061 |
0.415 |
|
1983 |
Ind PW, Miyatake A, Brown MJ, Dollery CT. Do human mast cells possess functional beta adrenoceptors in vivo? Agents and Actions. Supplements. 13: 245-54. PMID 6191554 |
0.358 |
|
1983 |
Ind PW, Barnes PJ, Brown MJ, Causon R, Dollery CT. Measurement of plasma histamine in asthma. Clinical Allergy. 13: 61-7. PMID 6187498 |
0.354 |
|
1982 |
Murphy MB, Scriven AJ, Brown MJ, Causon R, Dollery CT. The effects of nifedipine and hydralazine induced hypotension on sympathetic activity. European Journal of Clinical Pharmacology. 23: 479-82. PMID 7160415 DOI: 10.1007/Bf00637492 |
0.503 |
|
1982 |
Watkins J, Dargie HJ, Brown MJ, Krikler DM, Dollery CT. Effects of histamine type 2 receptor stimulation on myocardial function in normal subjects. British Heart Journal. 47: 539-45. PMID 7082501 DOI: 10.1136/Hrt.47.6.539 |
0.485 |
|
1982 |
Ind PW, Brown MJ, Lhoste FJ, Macquin I, Dollery CT. Concentration effect relationships of infused histamine in normal volunteers. Agents and Actions. 12: 12-6. PMID 7080947 |
0.414 |
|
1982 |
Brown MJ, Lhoste FJ, Zamboulis C, Ind PW, Jenner DA, Dollery CT. Estimation of sympathetic activity in essential hypertension. Clinical Pharmacology and Therapeutics. 31: 16-22. PMID 7053299 DOI: 10.1038/Clpt.1982.3 |
0.499 |
|
1982 |
Brown MJ, MacQuin I, Murphy M, Dollery C. Sustained Increase in Sympathetic Activity Due to Neuronal Uptake of Adrenaline: Mechanism for Stress-Induced Hypertension and Arrhythmias? Clinical Science. 62: 32P-32P. DOI: 10.1042/Cs062032Pa |
0.445 |
|
1981 |
Brown MJ, Jenner DA, Allison DJ, Dollery CT. Variations in individual organ release of noradrenaline measured by an improved radioenzymatic technique; limitations of peripheral venous measurements in the assessment of sympathetic nervous activity. Clinical Science (London, England : 1979). 61: 585-90. PMID 7285504 DOI: 10.1042/Cs0610585 |
0.482 |
|
1981 |
Miyamori I, Brown MJ, Dollery CT. Single-dose captopril administration in DOCA/salt rats: reduction of hypotensive effect by indomethacin. Clinical and Experimental Hypertension. 2: 935-45. PMID 7004806 DOI: 10.3109/10641968009037152 |
0.428 |
|
1981 |
Brown MJ, Dollery CT. A specific radioenzymatic assay for dihydroxyphenylalanine (DOPA). Plasma dopa may be the precursor of urine free dopamine. British Journal of Clinical Pharmacology. 11: 79-83. PMID 6783056 |
0.383 |
|
1981 |
Barnes PJ, Brown MJ, Silverman M, Dollery CT. Circulating catecholamines in exercise and hyperventilation induced asthma. Thorax. 36: 435-40. PMID 6274054 DOI: 10.1136/Thx.36.6.435 |
0.449 |
|
1981 |
Brown MJ, Allison DJ, Jenner DA, Lewis PJ, Dollery CT. Increased sensitivity and accuracy of phaeochromocytoma diagnosis achieved by use of plasma-adrenaline estimations and a pentolinium-suppression test. Lancet (London, England). 1: 174-7. PMID 6109856 DOI: 10.1016/S0140-6736(81)90058-1 |
0.487 |
|
1980 |
Brown MJ, Ind PW, Barnes PJ, Jenner DA, Dollery CT. A sensitive and specific radiometric method for the measurement of plasma histamine in normal individuals. Analytical Biochemistry. 109: 142-6. PMID 7469011 DOI: 10.1016/0003-2697(80)90022-6 |
0.46 |
|
1980 |
Brown MJ, Dollery CT, Fitzgerald GA, Watkins J, Zamboulis C. No evidence for antagonism of clonidine by naloxone in man [proceedings]. British Journal of Clinical Pharmacology. 9: 302P. PMID 7362753 |
0.343 |
|
1980 |
Rossor MN, Watkins J, Brown MJ, Reid JL, Dollery CT. Plasma levodopa, dopamine and therapeutic response following levodopa therapy of Parkinsonian patients. Journal of the Neurological Sciences. 46: 385-92. PMID 6991646 DOI: 10.1016/0022-510X(80)90063-5 |
0.386 |
|
1980 |
Watkins J, FitzGerald G, Zamboulis C, Brown MJ, Dollery CT. Absence of opiate and histamine H2 receptor-mediated effects of clonidine. Clinical Pharmacology and Therapeutics. 28: 605-10. PMID 6254720 DOI: 10.1038/Clpt.1980.210 |
0.485 |
|
1980 |
Karliner JS, Barnes P, Brown M, Dollery C. Chronic heart failure in the guinea pig increases cardiac alpha 1- and beta-adrenoceptors. European Journal of Pharmacology. 67: 115-8. PMID 6252020 DOI: 10.1016/0014-2999(80)90017-5 |
0.448 |
|
1980 |
Barnes P, FitzGerald G, Brown M, Dollery C. Nocturnal asthma and changes in circulating epinephrine, histamine, and cortisol. The New England Journal of Medicine. 303: 263-7. PMID 6247655 DOI: 10.1056/Nejm198007313030506 |
0.413 |
|
1980 |
Brown MJ, Lewis PJ, Dollery CT. Diagnosis of small phaeochromocytomas. Lancet (London, England). 1: 1185-6. PMID 6104000 DOI: 10.1016/S0140-6736(80)91638-4 |
0.401 |
|
1980 |
Miyamori I, FitzGerald GA, Brown MJ, Lewis PJ. Prostacyclin stimulates the renin angiotensin aldosterone system in man. The Journal of Clinical Endocrinology and Metabolism. 49: 943-4. PMID 389942 DOI: 10.1210/Jcem-49-6-943 |
0.323 |
|
1980 |
Barnes PJ, Brown MJ, Silverman M, Dollery CT. Catecholamines in Exercise and Hyperventilation-Induced Asthma Clinical Science. 58: 4P-4P. DOI: 10.1042/Cs058004Pb |
0.402 |
|
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